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Test your basic knowledge |
USMLE Pathophys
Start Test
Study First
Subjects
:
health-sciences
,
usmle
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. 3
What oncogene is a/w MEN 2a/b
abruptio placentae
whats the V/Q at the apex of the lung
solitarius nucleus
2. HTN; XY will be a girl - XX will lack secondary sex char.
brain tumor a/w von hipple - linadu syndrome
17 alpha hydroxylase deficiency
chief cells
what inhibits prolactin secretion
3. Placenta attached to myometrium
3 tumors of MEN 2a
21 hydroxylase deficiency
plenta accreta
strawberry tongue
4. Antitoxin - penicillin - DPT vaccine
sulfonylureas MofA
antibody against philadelphia chromosome
diphtheria treatment
most common testicular tumor
5. Complete
hydatidiform mole with crazy high hCG
brain tumor with psammona bodies
erythema nodosum
oligodendrioglia
6. Tay Sachs
palisading nuclei - locally invasive
GM2 ganglioside accumulation
psammoma bodies
melanoma tumor marker
7. Gauchers
most common primary cardiac tumor in kiddos
ventral posterior nucleus - medial part
beta glucocerebrosidase
Shigella
8. Damaged in Guillian Barre
schwann cells
erythema nodosum
whats the V/Q at the apex of the lung
3 tumors of MEN 2b
9. Achondroplasia
21 hydroxylase deficiency
blood supply for thalamus
polyhydramnios
FGFR3 mutation
10. Kawasaki
most common breast tumor in women under 25
vasculitis of infants and children - involving coronary arteries
brain tumor with fried egg appearance
rate limiting step in carb digestion
11. ITP
barbituates withdrawal
anti - platelet antibodies
subluxation of lens
brain tumor with perivascular pseudorosettes
12. Serous cystadenocarcinoma
which nerve lifts the eyelid?
alpha 1 anti - trypsin
ovarian tumor with psammoma bodies
metformin side effect
13. Inhibits osteoclastic activity
Yolk sac tumor produces...
inheritance pattern for all MENs
Bisphosphonates MofA
found in hairless skin
14. Rhabdomyoma
Galactocerebrosidase deficiency
most common primary cardiac tumor in kiddos
sumatriptan
failure of endodermal development
15. Legionella
What thyroid pathology has an extremely tender thyroid gland
alpha L iduronidase
silver stain of gram negative rods
abruptio placentae
16. Visceral sensory
palisading nuclei - locally invasive
cells destroyed in MS
solitarius nucleus
pseudopalisading necrosis
17. Papillary CA of thyroid
optically clear nuclei (orphan annie)
most common breast mass in pre - menopausal women
metformin side effect
resembles an onion in cross section
18. Medullary thyroid - pheochromocytoma - oral/intestinal ganglionueromatosis
3 tumors of MEN 2b
hallmark sign of COPD
cells destroyed in Guillain Barre
tumor composed of cytotrophoblasts and syncytiotrophoblasts
19. H. Influenza
cells destroyed in MS
5 alpha reductase deficiency
cancer arising from parafollicular C cells
gram + bacteria that requires NAD and hemin for growth
20. PNH
honey crusted lesions common around nose/lips
hemosiderinurea and thrombosis
fusion inhibitors
medial geniculate nucleus
21. Ovarian bengin tumor...looks like bladder
brenner tumor
UMN signs
catalase negative
supraoptic nucleus of hypothalamus
22. Second most common type of thyroid cancer
medial geniculate nucleus
PGI2 (prostacyclin))
lisch nodules
follicular
23. Closes K+ channel on B cells causing depolarization and thus calcium influx which causes insulin release
rate limiting step in carb digestion
ventral posterior nucleus - lateral part
sulfonylureas MofA
most common breast mass in pre - menopausal women
24. Benign - contains Reinke crystals - usually androgen producing
eczema/recurrent infections/thrombocytopenia
MPTP exposure causes depletion of what NT?
leydig cell tumor
which nerve lifts the eyelid?
25. Cowdry type A inclusions
oligohydramnios
Where does the dorsal column decussate?
most common first line agent for septic shock
intranuclear inclusions seen in herpes simplex encephalitis
26. Ach
parietal cells
H. flu
basal nucleus of Meynert
D cells
27. 6- mecaptopurine (metabolized by xanthine oxidase)
diphtheria treatment
bocks PRPP synthetase to block purine synthesis
lysosomal storage disease a/w renal disease
MPTP exposure causes depletion of what NT?
28. Oligodendrogila
looks like fried eggs under histologic staining
cells destroyed in MS
What causes coronary vasospasm as a SE?
spike and dome on microscope
29. Lymphoma
30. Dubin Johnson
treatment of malignant hyperthermia
grossly black liver
blocks ADP receptors to inhibit platelet aggregation
ovarian tumor with psammoma bodies
31. Primary biliary cirrhosis
most common first line agent for septic shock
which nerve lifts the eyelid?
anti - mitochondrial antibodies
Where does the lateral corticospinal decussate?
32. Meissner
found in hairless skin
LT C4 D4 E4
benzos antidote
most common first line agent for septic shock
33. Naloxone/naltrexone
opioids antidote
Lateral geniculate nucleus
What anti - hypertensive drug has the side effect of first dose orthostatic hypotension
defective tyrosine kinase
34. Niacin
LMN signs
hippocampus
mitral valve prolapse - liver diseae - berry aneurysm
SE: facial flushing
35. Meningioma
deficiency of mannose phosphorylation
looks like fried eggs under histologic staining
may lead to multiple personalities
brain tumor with psammona bodies
36. NF 1
what meds treat malaria
pigmented iris hamartomas - neural tumors
shown to slow progression of diabetic neuropathy
whats the V/Q at the apex of the lung
37. Vaginal carcinoma: spindle shaped tumor cells that are desmin positive
failure of endodermal development
21 hydroxylase deficiency
sarcoma botyroides
vasculitis a/w Hep B
38. Decreased follicles & estrogen with increased FSH & LH
which nerve lifts the eyelid?
hemangioblastomas of retina/cerebellum/medulla
erythema nodosum
What are the hormone changes seen in menopause
39. ADPKD
mitral valve prolapse - liver diseae - berry aneurysm
probenecid
3 tumors of MEN 2b
locus ceruleus
40. Inhibits platelet aggregation - promotes vasodilation and decreases uterine tone
G cells
PGI2 (prostacyclin))
ovarian tumor with elevate hCG
defective tyrosine kinase
41. Autosomal dominant
inheritance pattern for all MENs
order of nerve blockade
palisading nuclei - locally invasive
17 alpha hydroxylase deficiency
42. Prevents incorporation into host DNA
lewy body composition
Lateral geniculate nucleus
Lewy bodies composition
nucleoside reverse transcriptase inhibitors
43. Anti - TNF antibody - use for RA but watch out for latent TB!
infliximab
What oncogene is a/w MEN 2a/b
what nerve innervates the muscles of mastication?
mildly decreased UDPGT
44. Oligodendrioma
what inhibits prolactin secretion
palisading nuclei - locally invasive
brain tumor with fried egg appearance
Lateral geniculate nucleus
45. Auditory (Medial for Music)
whats the V/Q at the base of the lung
medial geniculate nucleus
glycine
oligohydramnios
46. Anxiety - seizures - delirium - life threatening CV collapse
P450 Inhibitors
oligodendrioglia
barbituates withdrawal
What hormones share a common alpha subunit
47. Fabrys
pseudopalisading necrosis
chief cells
alpha galacosidase A
locus ceruleus
48. Medulla
3 tumors of MEN 2b
MofA Levothyroxine
Where does the dorsal column decussate?
most common gyno malignancy
49. Ach
basal nucleus of Meynert
inheritance pattern for all MENs
SICK PEG
Schiller Duval bodies
50. Choriocarcinoma
tumor composed of cytotrophoblasts and syncytiotrophoblasts
H. flu
brain tumor a/w von hipple - linadu syndrome
SE: facial flushing