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Test your basic knowledge |
Bio Engineering
Start Test
Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Rather than randomly moving - moves in a directed cell migration manner for specific functions.
chemotaxis
Thrombin
Lower
photoactive polymers
2. The process of calibration establishes a quantitative relationship between ____ __ ___ _____ and the direct output of the intstrument (for example time/volume in GPC).
standards of known properties
Permanent - replicate
low
Chemotaxis
3. Two things needed in the end product of the creation of a scab
Hemophilia
Polymers - cross linking of polymers
Stress
micromachining
4. A condensation polymerization results with an ester bond between two reactants and this comes off as a result
Stable cells
Water
Calibration
Amide
5. The trigger for activation of enzymes (anything but endothelial cells!)
binding
autologous
photoactive polymers
Thrombin
6. Where are the tissue factors found when they're inactivated
Polymers - cross linking of polymers
free radical
cycles
in cytoplasm
7. The glass transition temperature of a poymer at which a polymer transforms from a ____ state to a ___ state.
Hemocompatibility
Proteases
glassy to rubbery
low
8. Cells that don't proliferate (neurons)
Plastic
Positive Feedback
Permanent cells
Heparin
9. Resulting from the build up of too much collagen at the surface of injury during the granulation tissue stage of proliferation
Intermolecular bonding - molecular weight
Hemocompatibility
scars
Metals
10. Keloid scars form due to disfunction of ____.
Chemotaxis
Stress
autologous
Collagenase/Remodelling
11. Process of producing new blood vessels due to a lack on oxygen and thus inducing VEGF.
Higher
autologous
angiogenesis
Free Radical
12. The fibrous capsule surrounding a permanent implant is primarily composed of ___ cells and ____ (matrix).
Plastic
Mast - Collagen
Amide
fibrinogen - factor XIII
13. What type of materials are used for photolithography? (substrate is a silicon wafer - built up material is some _____ ____ )
standards of known properties
Metals
Stable cells
photoactive polymers
14. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure
Thermoplastics
glassy to rubbery
Stress
Permanent - replicate
15. ____ grafts are derived from the other humans.
neutrophils - macrophages
Stable cells
Allogeneic
photoactive polymers
16. Classify the following polymers into appropriate families based on their bond structure i.e. the polymer is an example of poly ____.
phagocytosis
standards of known properties
Amide
Water
17. Disfunction of _____ (cells) producing collagenase during the _____ phase of wound healing may form Keloid scars.
macrophages - proliferation
Stable cells
labile cells
Thrombin
18. This type of feedback creates
autologous
fibrinogen - factor XIII
cycles
negative feedback
19. Thrombin activates several upstream factors.
Damage to cell membranes
Stress
phagocytosis
Positive Feedback
20. A molecular pathway in which the product of each reaction catalyzes the subsequent reaction.
Polydesperity index
Thrombin
Bioactive
Enzyme cascade
21. What types of wound healing results from injury with inflammation?
Thrombin
Regeneration/Repair
Hemophilia
Damage to cell membranes
22. In order to produce a blood clot - thrombin cleaves/activates ____ and ____.
Negative Feedback
Heparin
fibrinogen - factor XIII
Collagenase
23. Activates tissue factors aka endothelial damage
Number of polymers - molecular weight of polymer
Intermolecular bonding - molecular weight
Negative Feedback
Damage to cell membranes
24. High conductivity - isotropic - crystalline
Positive Feedback
Metals
stress
fibrinogen - factor XIII
25. ____ binds to anti- thrombin III (thrombin inhibitor) and increases its potency 1000- fold.
Permanent cells
labile cells
negative feedback
Heparin
26. ____ describes the ability of a device to function appropriately in the presence of blood.
Endothelial cells
Hemocompatibility
Compression molding
Plasticizers
27. The fatigue limit is value of applied stress below which a material will not fail no matter the number of ____ applied.
cycles
autologous
Plasticizers
Stress
28. Damaged cells at the site of injury (mast cells) release ___ (glycosaminoglycan).
heparin
scars
Large
Higher
29. Essentially all metallic biomaterials are ____ - comprised of two or more metals. One of these metals is selected for its ability to support _____ - the formation of a stable oxide layer that resists further corrosion.
Endothelial cells
labile cells
Chemotaxis
alloys - passivation
30. List two chemical characteristics of polymers:
cross - linking
Intermolecular bonding - molecular weight
Mast - Collagen
micromachining
31. Is directed cell migration in response to a concentration gradient of soluble molecules.
Chemotaxis
alloys - passivation
low
Number of polymers - molecular weight of polymer
32. Collagen ____ is responsible for the gradual gain in mechanical properties of wounded tissue between roughly 4 and 52 weeks post- injury.
cross - linking
in cytoplasm
Positive Feedback
Thrombin
33. Keloid scars forms because disfuntion of
cycles
micromachining
Positive Feedback
Collagenase
34. You're working on a square polymeric implant of 5cm length and 2mm thick. You've been asked to suggest a precise way to fabricate it - what would you suggest?
scars
Plasticizers
Compression molding
phagocytosis
35. Thrombin also activates protein C-- which deactivates earlier factors in the cascade is known as ___ ___.
Negative Feedback
hypoxin - angiogenesis
Macrophages
Have to be in a clean room free of dust and biocontamination - expensive
36. Enzyme that really gets the polmerization going!
stress
heparin
Thrombin
Extrusion
37. Deformation that cannot be recovered once the load is removed from the material is ____ deformation.
Bioactive
Hemocompatibility
micromachining
Plastic
38. Drawback of micromaching
Plastic
Endothelial cells
Have to be in a clean room free of dust and biocontamination - expensive
stress
39. ____- are polymers that can be repeatedly softened by heating and hardened by cooling.
Enzyme cascade
Thermoplastics
phagocytosis
Mast - Collagen
40. ____ is a measurement that characterizes the breadth of the distribution of a polymer's molecular weight.
Hemocompatibility
Intermolecular bonding - molecular weight
Polydesperity index
Phagocytosis
41. Are polymer additives used to lower glass transition temperature temperature.
Stress
negative feedback
free radical
Plasticizers
42. GPC separates molecules on the basis of size by their passage over a column packed with a porous matrix. ___ molecules pass through the column more quickly.
Stable cells
Endothelial cells
Large
Allogeneic
43. Process that makes long fibers (fiber drawing) by forcing a fluid through an oriface.
cross - linking
Extrusion
Proteases
Stress
44. Vascular endothelial growth factor is produced in response to ___ and stimulates ___.
Stress
hypoxin - angiogenesis
Proteases
Free Radical
45. Foreign body giants cells are produced by fusion of ___.
Collagenase
Proteases
scars
Macrophages
46. A ____ implant is designed to elicit specific - intended to host responses.
Thrombin
Positive Feedback
Bioactive
Water
47. The two types of white blood cells:
neutrophils - macrophages
Plastic
in cytoplasm
Proteases
48. ____ are enzymes responsible for protein degradation.
glassy to rubbery
Collagenase
micromachining
Proteases
49. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure.
Collagenase
stress
Number of polymers - molecular weight of polymer
Mast - Collagen
50. Cells that proliferate slowly over time (aka liver)
Mast - Collagen
hypoxin - angiogenesis
Proteases
Stable cells