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Bio Engineering
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Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
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.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. The fibrous capsule surrounding a permanent implant is primarily composed of ___ cells and ____ (matrix).
Lower
Free Radical
Mast - Collagen
cycles
2. Two things needed in the end product of the creation of a scab
Negative Feedback
Thermoplastics
Polymers - cross linking of polymers
Proteases
3. Mast cells release this
Plastic
Endothelial cells
Stable cells
heparin
4. Are polymer additives used to lower glass transition temperature temperature.
Plasticizers
Thrombin
Hemophilia
Permanent - replicate
5. Process of producing new blood vessels due to a lack on oxygen and thus inducing VEGF.
alloys - passivation
Plasticizers
Hemocompatibility
angiogenesis
6. _____ establishes a quantitative relationship between measured output values from an instrument and known standards of what is being measured.
Have to be in a clean room free of dust and biocontamination - expensive
cycles
binding
Calibration
7. Cardiac bypass surgery in which a vein from a patient's leg is transplanted to the patient's heart is an example of the us of ____ tissue.
autologous
Macrophages
Higher
in cytoplasm
8. A ____ implant is designed to elicit specific - intended to host responses.
heparin
Hemocompatibility
Bioactive
phagocytosis
9. You're working on a square polymeric implant of 5cm length and 2mm thick. You've been asked to suggest a precise way to fabricate it - what would you suggest?
Water
Polydesperity index
standards of known properties
Compression molding
10. The fatigue limit is value of applied stress below which a material will not fail no matter the number of ____ applied.
Damage to cell membranes
Bioactive
Mast - Collagen
cycles
11. This cleaves into fibrinogen which creates fibrin (a sticky enzyme that allows blood to clot)
Thrombin
negative feedback
Extrusion
Damage to cell membranes
12. Cells that don't proliferate (neurons)
Macrophages
Stable cells
Calibration
Permanent cells
13. Disfunction of _____ (cells) producing collagenase during the _____ phase of wound healing may form Keloid scars.
Intermolecular bonding - molecular weight
Damage to cell membranes
Mast - Collagen
macrophages - proliferation
14. Collagen ____ is responsible for the gradual gain in mechanical properties of wounded tissue between roughly 4 and 52 weeks post- injury.
heparin
labile cells
heparin
cross - linking
15. Enzyme that really gets the polmerization going!
chemotaxis
Mast - Collagen
autologous
Thrombin
16. Enzymes (proteins) are not activated only when they are in contact with this type of cells
labile cells
Stress
Metals
Endothelial cells
17. List two chemical characteristics of polymers:
Calibration
Thermoplastics
Intermolecular bonding - molecular weight
Thrombin
18. Addition polymerization is commonly initiated by ___ - atoms that have an unpaired electron.
Polymers - cross linking of polymers
free radical
labile cells
Chemotaxis
19. Rather than randomly moving - moves in a directed cell migration manner for specific functions.
alloys - passivation
Water - oxygen - metal
Phagocytosis
chemotaxis
20. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure
autologous
cycles
Plastic
Stress
21. Polyethylene oxide grafting to biomaterials was developed to prevent coagulation by interfering with/preventing ___ ___.
standards of known properties
Stress
Protein Absorption
heparin
22. Cells that proliferate slowly over time (aka liver)
Number of polymers - molecular weight of polymer
Stable cells
Thrombin
fibrinogen - factor XIII
23. The trigger for activation of enzymes (anything but endothelial cells!)
cycles
free radical
Regeneration/Repair
binding
24. Keloid scars form due to disfunction of ____.
photoactive polymers
Collagenase/Remodelling
Lower
Compression molding
25. Vascular endothelial growth factor is produced in response to ___ and stimulates ___.
Permanent - replicate
hypoxin - angiogenesis
macrophages - proliferation
negative feedback
26. Neutrophils remove bacteria/damaged cell debris from a wound site through the process of ___.
Chemotaxis
Collagenase/Remodelling
Calibration
phagocytosis
27. In order to produce a blood clot - thrombin cleaves/activates ____ and ____.
heparin
free radical
fibrinogen - factor XIII
Permanent - replicate
28. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure.
macrophages - proliferation
phagocytosis
alloys - passivation
stress
29. Cells that proliferate rapidly (fibroblasts)
Proteases
Enzyme cascade
Thrombin
labile cells
30. The glass transition temperature of a poymer at which a polymer transforms from a ____ state to a ___ state.
angiogenesis
Permanent cells
Bioactive
glassy to rubbery
31. ______ Molecular weight degrades slower than lower MW
Phagocytosis
Hemocompatibility
Regeneration/Repair
Higher
32. Deformation that cannot be recovered once the load is removed from the material is ____ deformation.
Plastic
Calibration
Free Radical
Lower
33. Classify the following polymers into appropriate families based on their bond structure i.e. the polymer is an example of poly ____.
Thermoplastics
Amide
Compression molding
autologous
34. ____ is the process by which cells involved in inflammation internalize and destroy foreign material.
Phagocytosis
Endothelial cells
Proteases
Lower
35. ____ is a measurement that characterizes the breadth of the distribution of a polymer's molecular weight.
Chemotaxis
Polydesperity index
Plasticizers
Allogeneic
36. What types of wound healing results from injury with inflammation?
Regeneration/Repair
fibrinogen - factor XIII
free radical
Polydesperity index
37. Resulting from the build up of too much collagen at the surface of injury during the granulation tissue stage of proliferation
Plastic
Proteases
Free Radical
scars
38. Foreign body giants cells are produced by fusion of ___.
Macrophages
Regeneration/Repair
Endothelial cells
labile cells
39. This type of feedback creates
Thrombin
Enzyme cascade
Phagocytosis
negative feedback
40. Condition in which patients can literally bleed to death.
Hemophilia
heparin
Positive Feedback
Permanent cells
41. Type of fiber drawing that controls details of a polymer by etching on a microscopic level; thus - controlling mechanical properties as well
Heparin
Extrusion
micromachining
Chemotaxis
42. The two types of white blood cells:
neutrophils - macrophages
macrophages - proliferation
Collagenase/Remodelling
Water - oxygen - metal
43. Where are the tissue factors found when they're inactivated
Higher
fibrinogen - factor XIII
Allogeneic
in cytoplasm
44. Thrombin also activates protein C-- which deactivates earlier factors in the cascade is known as ___ ___.
Stable cells
Regeneration/Repair
Negative Feedback
Higher
45. Keloid scars forms because disfuntion of
Collagenase
Large
neutrophils - macrophages
Have to be in a clean room free of dust and biocontamination - expensive
46. During granulation stage of proliferation - growth factors that produce this ____(answer)_____ that function in degrading fibrin and replacing it with collagen.
Amide
cycles
Proteases
heparin
47. High conductivity - isotropic - crystalline
Proteases
Metals
autologous
Stable cells
48. Process that makes long fibers (fiber drawing) by forcing a fluid through an oriface.
Extrusion
micromachining
stress
Stable cells
49. No healing of damage neurons is the result of ____ cells that are not able to ____.
Permanent cells
Permanent - replicate
Water
glassy to rubbery
50. The calculation of a polymer's molecular weight (weight average and number number average) is based upon values for ____ and ___.
Macrophages
Number of polymers - molecular weight of polymer
Plasticizers
Hemophilia
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