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Test your basic knowledge |
Bio Engineering
Start Test
Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Cell found in the lining of the blood vessels that release heparin and are a part of the negative feedback system.
Collagenase
Thermoplastics
Polymers - cross linking of polymers
mast cells
2. Cells that proliferate rapidly (fibroblasts)
Bioactive
Thrombin
Negative Feedback
labile cells
3. Polyethylene oxide grafting to biomaterials was developed to prevent coagulation by interfering with/preventing ___ ___.
Endothelial cells
chemotaxis
Polymers - cross linking of polymers
Protein Absorption
4. Foreign body giants cells are produced by fusion of ___.
Hemophilia
Macrophages
labile cells
mast cells
5. The process of calibration establishes a quantitative relationship between ____ __ ___ _____ and the direct output of the intstrument (for example time/volume in GPC).
Heparin
standards of known properties
Collagenase
heparin
6. The trigger for activation of enzymes (anything but endothelial cells!)
binding
Thrombin
Damage to cell membranes
Polymers - cross linking of polymers
7. In order to produce a blood clot - thrombin cleaves/activates ____ and ____.
binding
Endothelial cells
fibrinogen - factor XIII
neutrophils - macrophages
8. _____ establishes a quantitative relationship between measured output values from an instrument and known standards of what is being measured.
Mast - Collagen
Calibration
Intermolecular bonding - molecular weight
alloys - passivation
9. Neutrophils remove bacteria/damaged cell debris from a wound site through the process of ___.
phagocytosis
Endothelial cells
Lower
Free Radical
10. During granulation stage of proliferation - growth factors that produce this ____(answer)_____ that function in degrading fibrin and replacing it with collagen.
Macrophages
Water
Lower
Proteases
11. Process of producing new blood vessels due to a lack on oxygen and thus inducing VEGF.
angiogenesis
Have to be in a clean room free of dust and biocontamination - expensive
cycles
labile cells
12. The calculation of a polymer's molecular weight (weight average and number number average) is based upon values for ____ and ___.
standards of known properties
Collagenase/Remodelling
angiogenesis
Number of polymers - molecular weight of polymer
13. Drawback of micromaching
Thrombin
Have to be in a clean room free of dust and biocontamination - expensive
in cytoplasm
Endothelial cells
14. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure
Stress
Positive Feedback
Hemophilia
Permanent - replicate
15. Is directed cell migration in response to a concentration gradient of soluble molecules.
Stress
Compression molding
scars
Chemotaxis
16. Cells that proliferate slowly over time (aka liver)
Stable cells
Calibration
negative feedback
Negative Feedback
17. Relative to free radical polymerization - condensation polymerization generally produces polymer of relatively ____ molecular weight.
Polymers - cross linking of polymers
low
fibrinogen - factor XIII
alloys - passivation
18. Cardiac bypass surgery in which a vein from a patient's leg is transplanted to the patient's heart is an example of the us of ____ tissue.
autologous
Collagenase/Remodelling
alloys - passivation
mast cells
19. Cells that don't proliferate (neurons)
Permanent cells
Thermoplastics
Large
Stable cells
20. Keloid scars form due to disfunction of ____.
Heparin
macrophages - proliferation
mast cells
Collagenase/Remodelling
21. ______ Molecular weight degrades slower than lower MW
Heparin
Number of polymers - molecular weight of polymer
Lower
Higher
22. Condition in which patients can literally bleed to death.
Polymers - cross linking of polymers
Thrombin
Hemophilia
Macrophages
23. ____ are enzymes responsible for protein degradation.
Permanent cells
Extrusion
Higher
Proteases
24. The fatigue limit is value of applied stress below which a material will not fail no matter the number of ____ applied.
cycles
Hemophilia
Intermolecular bonding - molecular weight
Polydesperity index
25. Where are the tissue factors found when they're inactivated
macrophages - proliferation
Compression molding
in cytoplasm
Thrombin
26. Resulting from the build up of too much collagen at the surface of injury during the granulation tissue stage of proliferation
Polymers - cross linking of polymers
scars
Phagocytosis
Protein Absorption
27. This type of feedback creates
cross - linking
Stable cells
Number of polymers - molecular weight of polymer
negative feedback
28. Collagen ____ is responsible for the gradual gain in mechanical properties of wounded tissue between roughly 4 and 52 weeks post- injury.
free radical
Water
labile cells
cross - linking
29. Damaged cells at the site of injury (mast cells) release ___ (glycosaminoglycan).
Endothelial cells
Macrophages
Chemotaxis
heparin
30. This cleaves into fibrinogen which creates fibrin (a sticky enzyme that allows blood to clot)
Extrusion
Permanent - replicate
Thrombin
labile cells
31. The formation of rust due to corrosion in the body is due to the reaction between these 3 things ____ - ____ - and ____ .
Water - oxygen - metal
low
Lower
Thermoplastics
32. What types of wound healing results from injury with inflammation?
Regeneration/Repair
Metals
Thermoplastics
macrophages - proliferation
33. ____- are polymers that can be repeatedly softened by heating and hardened by cooling.
labile cells
Stable cells
Damage to cell membranes
Thermoplastics
34. List two chemical characteristics of polymers:
Number of polymers - molecular weight of polymer
Stress
macrophages - proliferation
Intermolecular bonding - molecular weight
35. Process that makes long fibers (fiber drawing) by forcing a fluid through an oriface.
Extrusion
Calibration
Chemotaxis
Protein Absorption
36. ____ describes the ability of a device to function appropriately in the presence of blood.
Enzyme cascade
alloys - passivation
Thermoplastics
Hemocompatibility
37. ____ is the process by which cells involved in inflammation internalize and destroy foreign material.
Permanent cells
Phagocytosis
Enzyme cascade
Intermolecular bonding - molecular weight
38. GPC separates molecules on the basis of size by their passage over a column packed with a porous matrix. ___ molecules pass through the column more quickly.
Large
Bioactive
Stress
Collagenase
39. Addition polymerization is commonly initiated by ___ - atoms that have an unpaired electron.
glassy to rubbery
Stable cells
Hemophilia
free radical
40. Are polymer additives used to lower glass transition temperature temperature.
Large
Plasticizers
Water
Higher
41. The two types of white blood cells:
neutrophils - macrophages
Chemotaxis
negative feedback
Mast - Collagen
42. Deformation that cannot be recovered once the load is removed from the material is ____ deformation.
Hemophilia
Chemotaxis
Bioactive
Plastic
43. Disfunction of _____ (cells) producing collagenase during the _____ phase of wound healing may form Keloid scars.
macrophages - proliferation
Permanent - replicate
Number of polymers - molecular weight of polymer
Amide
44. Essentially all metallic biomaterials are ____ - comprised of two or more metals. One of these metals is selected for its ability to support _____ - the formation of a stable oxide layer that resists further corrosion.
Phagocytosis
Polydesperity index
alloys - passivation
heparin
45. You're working on a square polymeric implant of 5cm length and 2mm thick. You've been asked to suggest a precise way to fabricate it - what would you suggest?
Collagenase
Collagenase/Remodelling
stress
Compression molding
46. Type of fiber drawing that controls details of a polymer by etching on a microscopic level; thus - controlling mechanical properties as well
Collagenase/Remodelling
Thrombin
micromachining
Hemophilia
47. The fibrous capsule surrounding a permanent implant is primarily composed of ___ cells and ____ (matrix).
Enzyme cascade
fibrinogen - factor XIII
Mast - Collagen
Collagenase
48. Thrombin activates several upstream factors.
Thrombin
Positive Feedback
alloys - passivation
Phagocytosis
49. A ____ implant is designed to elicit specific - intended to host responses.
Metals
Thrombin
Free Radical
Bioactive
50. Classify the following polymers into appropriate families based on their bond structure i.e. the polymer is an example of poly ____.
Endothelial cells
Stable cells
Amide
fibrinogen - factor XIII