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Test your basic knowledge |
Bio Engineering
Start Test
Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. ____ are enzymes responsible for protein degradation.
Number of polymers - molecular weight of polymer
stress
Proteases
Thermoplastics
2. Classify the following polymers into appropriate families based on their bond structure i.e. the polymer is an example of poly ____.
Amide
Metals
free radical
Water
3. Drawback of micromaching
Stable cells
Heparin
Thrombin
Have to be in a clean room free of dust and biocontamination - expensive
4. ____ is a measurement that characterizes the breadth of the distribution of a polymer's molecular weight.
Hemocompatibility
macrophages - proliferation
Intermolecular bonding - molecular weight
Polydesperity index
5. Keloid scars forms because disfuntion of
micromachining
Endothelial cells
Large
Collagenase
6. The glass transition temperature of a poymer at which a polymer transforms from a ____ state to a ___ state.
glassy to rubbery
alloys - passivation
Collagenase
Polymers - cross linking of polymers
7. The formation of rust due to corrosion in the body is due to the reaction between these 3 things ____ - ____ - and ____ .
Stable cells
cycles
Number of polymers - molecular weight of polymer
Water - oxygen - metal
8. During granulation stage of proliferation - growth factors that produce this ____(answer)_____ that function in degrading fibrin and replacing it with collagen.
Proteases
fibrinogen - factor XIII
heparin
Stress
9. A ____ implant is designed to elicit specific - intended to host responses.
angiogenesis
Bioactive
low
Hemophilia
10. Condition in which patients can literally bleed to death.
Collagenase/Remodelling
Hemophilia
cycles
phagocytosis
11. Is directed cell migration in response to a concentration gradient of soluble molecules.
in cytoplasm
cross - linking
Macrophages
Chemotaxis
12. Foreign body giants cells are produced by fusion of ___.
Chemotaxis
Macrophages
Intermolecular bonding - molecular weight
neutrophils - macrophages
13. The calculation of a polymer's molecular weight (weight average and number number average) is based upon values for ____ and ___.
Water - oxygen - metal
Chemotaxis
Intermolecular bonding - molecular weight
Number of polymers - molecular weight of polymer
14. Resulting from the build up of too much collagen at the surface of injury during the granulation tissue stage of proliferation
Higher
scars
neutrophils - macrophages
heparin
15. Relative to free radical polymerization - condensation polymerization generally produces polymer of relatively ____ molecular weight.
low
Stress
Damage to cell membranes
Hemocompatibility
16. A molecular pathway in which the product of each reaction catalyzes the subsequent reaction.
negative feedback
Mast - Collagen
Thrombin
Enzyme cascade
17. Cells that proliferate slowly over time (aka liver)
Stable cells
autologous
Damage to cell membranes
Thermoplastics
18. Enzymes (proteins) are not activated only when they are in contact with this type of cells
Enzyme cascade
Hemophilia
Endothelial cells
Calibration
19. Thrombin also activates protein C-- which deactivates earlier factors in the cascade is known as ___ ___.
Proteases
Protein Absorption
Heparin
Negative Feedback
20. Type of fiber drawing that controls details of a polymer by etching on a microscopic level; thus - controlling mechanical properties as well
chemotaxis
low
Macrophages
micromachining
21. List two chemical characteristics of polymers:
Collagenase/Remodelling
Intermolecular bonding - molecular weight
Hemophilia
Large
22. Polyethylene oxide grafting to biomaterials was developed to prevent coagulation by interfering with/preventing ___ ___.
scars
labile cells
Protein Absorption
negative feedback
23. ____ grafts are derived from the other humans.
low
Allogeneic
Water
fibrinogen - factor XIII
24. The trigger for activation of enzymes (anything but endothelial cells!)
binding
Have to be in a clean room free of dust and biocontamination - expensive
heparin
Collagenase
25. The fibrous capsule surrounding a permanent implant is primarily composed of ___ cells and ____ (matrix).
glassy to rubbery
heparin
Mast - Collagen
angiogenesis
26. Addition polymerization is commonly initiated by ___ - atoms that have an unpaired electron.
Protein Absorption
autologous
free radical
Extrusion
27. ______ Molecular weight degrades slower than lower MW
Positive Feedback
Plastic
Higher
Permanent cells
28. No healing of damage neurons is the result of ____ cells that are not able to ____.
Lower
macrophages - proliferation
Plastic
Permanent - replicate
29. The two types of white blood cells:
Macrophages
Free Radical
neutrophils - macrophages
hypoxin - angiogenesis
30. You're working on a square polymeric implant of 5cm length and 2mm thick. You've been asked to suggest a precise way to fabricate it - what would you suggest?
Have to be in a clean room free of dust and biocontamination - expensive
Compression molding
Proteases
micromachining
31. This cleaves into fibrinogen which creates fibrin (a sticky enzyme that allows blood to clot)
cross - linking
macrophages - proliferation
Positive Feedback
Thrombin
32. What types of wound healing results from injury with inflammation?
Thermoplastics
Chemotaxis
Regeneration/Repair
Mast - Collagen
33. ____ describes the ability of a device to function appropriately in the presence of blood.
Hemocompatibility
Hemophilia
Stable cells
Permanent cells
34. Essentially all metallic biomaterials are ____ - comprised of two or more metals. One of these metals is selected for its ability to support _____ - the formation of a stable oxide layer that resists further corrosion.
alloys - passivation
Regeneration/Repair
Damage to cell membranes
Water
35. Enzyme that really gets the polmerization going!
in cytoplasm
angiogenesis
Extrusion
Thrombin
36. Disfunction of _____ (cells) producing collagenase during the _____ phase of wound healing may form Keloid scars.
Stable cells
macrophages - proliferation
Calibration
Macrophages
37. Are polymer additives used to lower glass transition temperature temperature.
Plasticizers
Collagenase
Negative Feedback
standards of known properties
38. ____ binds to anti- thrombin III (thrombin inhibitor) and increases its potency 1000- fold.
Heparin
Polydesperity index
Compression molding
free radical
39. Cells that don't proliferate (neurons)
Permanent cells
Hemophilia
angiogenesis
scars
40. Where are the tissue factors found when they're inactivated
Collagenase/Remodelling
Collagenase
cycles
in cytoplasm
41. In order to produce a blood clot - thrombin cleaves/activates ____ and ____.
standards of known properties
fibrinogen - factor XIII
macrophages - proliferation
free radical
42. Cardiac bypass surgery in which a vein from a patient's leg is transplanted to the patient's heart is an example of the us of ____ tissue.
cycles
heparin
autologous
Polymers - cross linking of polymers
43. Activates tissue factors aka endothelial damage
Stress
Damage to cell membranes
Proteases
Permanent cells
44. Rather than randomly moving - moves in a directed cell migration manner for specific functions.
Mast - Collagen
glassy to rubbery
chemotaxis
negative feedback
45. A condensation polymerization results with an ester bond between two reactants and this comes off as a result
Plastic
phagocytosis
negative feedback
Water
46. Cells that proliferate rapidly (fibroblasts)
binding
cycles
labile cells
micromachining
47. Vascular endothelial growth factor is produced in response to ___ and stimulates ___.
hypoxin - angiogenesis
negative feedback
Polydesperity index
heparin
48. Mast cells release this
labile cells
Hemocompatibility
free radical
heparin
49. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure
Protein Absorption
Stress
Bioactive
Thrombin
50. _____ establishes a quantitative relationship between measured output values from an instrument and known standards of what is being measured.
Plastic
cycles
Phagocytosis
Calibration