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Test your basic knowledge |
Bio Engineering
Start Test
Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Vascular endothelial growth factor is produced in response to ___ and stimulates ___.
hypoxin - angiogenesis
fibrinogen - factor XIII
labile cells
Lower
2. No healing of damage neurons is the result of ____ cells that are not able to ____.
Water - oxygen - metal
Collagenase/Remodelling
Chemotaxis
Permanent - replicate
3. Collagen ____ is responsible for the gradual gain in mechanical properties of wounded tissue between roughly 4 and 52 weeks post- injury.
mast cells
heparin
Thrombin
cross - linking
4. ____ binds to anti- thrombin III (thrombin inhibitor) and increases its potency 1000- fold.
Polydesperity index
Phagocytosis
Heparin
low
5. ____ are enzymes responsible for protein degradation.
low
Thermoplastics
Compression molding
Proteases
6. The calculation of a polymer's molecular weight (weight average and number number average) is based upon values for ____ and ___.
Stress
cycles
Water - oxygen - metal
Number of polymers - molecular weight of polymer
7. ____ is a measurement that characterizes the breadth of the distribution of a polymer's molecular weight.
heparin
stress
Polydesperity index
Permanent - replicate
8. Higher Molecular weight degrades slower than ____ MW
Have to be in a clean room free of dust and biocontamination - expensive
free radical
Lower
Collagenase/Remodelling
9. High conductivity - isotropic - crystalline
Higher
scars
Metals
Collagenase/Remodelling
10. This type of feedback creates
Stress
micromachining
negative feedback
Hemophilia
11. Keloid scars forms because disfuntion of
Permanent - replicate
Collagenase
Polydesperity index
Heparin
12. GPC separates molecules on the basis of size by their passage over a column packed with a porous matrix. ___ molecules pass through the column more quickly.
in cytoplasm
Plastic
Extrusion
Large
13. Process of producing new blood vessels due to a lack on oxygen and thus inducing VEGF.
Polymers - cross linking of polymers
Polydesperity index
Amide
angiogenesis
14. Neutrophils remove bacteria/damaged cell debris from a wound site through the process of ___.
Large
Stable cells
photoactive polymers
phagocytosis
15. List two chemical characteristics of polymers:
Permanent - replicate
Collagenase/Remodelling
Thrombin
Intermolecular bonding - molecular weight
16. Cells that proliferate slowly over time (aka liver)
Stable cells
Higher
micromachining
Positive Feedback
17. Thrombin activates several upstream factors.
micromachining
Compression molding
Positive Feedback
Stress
18. A ____ implant is designed to elicit specific - intended to host responses.
glassy to rubbery
Bioactive
free radical
Water
19. The fibrous capsule surrounding a permanent implant is primarily composed of ___ cells and ____ (matrix).
Plastic
Mast - Collagen
hypoxin - angiogenesis
Have to be in a clean room free of dust and biocontamination - expensive
20. Disfunction of _____ (cells) producing collagenase during the _____ phase of wound healing may form Keloid scars.
fibrinogen - factor XIII
macrophages - proliferation
cycles
angiogenesis
21. Which of polyermization (condensation/free radical) would you choose to obtain a polymer of high molecular weight?
Calibration
hypoxin - angiogenesis
Free Radical
Polymers - cross linking of polymers
22. The two types of white blood cells:
Macrophages
Polymers - cross linking of polymers
neutrophils - macrophages
Heparin
23. ____- are polymers that can be repeatedly softened by heating and hardened by cooling.
Proteases
Thermoplastics
Stress
labile cells
24. Type of fiber drawing that controls details of a polymer by etching on a microscopic level; thus - controlling mechanical properties as well
cross - linking
micromachining
heparin
Proteases
25. What types of wound healing results from injury with inflammation?
standards of known properties
Regeneration/Repair
glassy to rubbery
Compression molding
26. The formation of rust due to corrosion in the body is due to the reaction between these 3 things ____ - ____ - and ____ .
Heparin
Permanent cells
Metals
Water - oxygen - metal
27. ____ is the process by which cells involved in inflammation internalize and destroy foreign material.
Have to be in a clean room free of dust and biocontamination - expensive
Water - oxygen - metal
Phagocytosis
standards of known properties
28. ____ describes the ability of a device to function appropriately in the presence of blood.
photoactive polymers
Water
Hemocompatibility
stress
29. Deformation that cannot be recovered once the load is removed from the material is ____ deformation.
Plasticizers
Lower
Plastic
Thrombin
30. This cleaves into fibrinogen which creates fibrin (a sticky enzyme that allows blood to clot)
scars
Polydesperity index
cross - linking
Thrombin
31. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure.
neutrophils - macrophages
Plasticizers
Damage to cell membranes
stress
32. Polyethylene oxide grafting to biomaterials was developed to prevent coagulation by interfering with/preventing ___ ___.
negative feedback
Protein Absorption
Heparin
heparin
33. The fatigue limit is value of applied stress below which a material will not fail no matter the number of ____ applied.
negative feedback
Protein Absorption
labile cells
cycles
34. Activates tissue factors aka endothelial damage
Bioactive
Polydesperity index
Damage to cell membranes
Stable cells
35. Mast cells release this
heparin
cross - linking
macrophages - proliferation
Proteases
36. Cell found in the lining of the blood vessels that release heparin and are a part of the negative feedback system.
mast cells
Water - oxygen - metal
Permanent - replicate
cross - linking
37. Damaged cells at the site of injury (mast cells) release ___ (glycosaminoglycan).
heparin
Bioactive
Thrombin
Water - oxygen - metal
38. Cardiac bypass surgery in which a vein from a patient's leg is transplanted to the patient's heart is an example of the us of ____ tissue.
Thrombin
standards of known properties
autologous
micromachining
39. Cells that don't proliferate (neurons)
Proteases
Number of polymers - molecular weight of polymer
cross - linking
Permanent cells
40. Is directed cell migration in response to a concentration gradient of soluble molecules.
glassy to rubbery
Chemotaxis
Allogeneic
Stress
41. The trigger for activation of enzymes (anything but endothelial cells!)
Allogeneic
Amide
Plastic
binding
42. Condition in which patients can literally bleed to death.
Collagenase
Damage to cell membranes
Compression molding
Hemophilia
43. In order to produce a blood clot - thrombin cleaves/activates ____ and ____.
low
fibrinogen - factor XIII
neutrophils - macrophages
photoactive polymers
44. Rather than randomly moving - moves in a directed cell migration manner for specific functions.
chemotaxis
Regeneration/Repair
Permanent cells
Permanent - replicate
45. ______ Molecular weight degrades slower than lower MW
Mast - Collagen
Higher
Water
Allogeneic
46. Relative to free radical polymerization - condensation polymerization generally produces polymer of relatively ____ molecular weight.
low
Regeneration/Repair
Lower
Amide
47. Process that makes long fibers (fiber drawing) by forcing a fluid through an oriface.
Enzyme cascade
hypoxin - angiogenesis
phagocytosis
Extrusion
48. A molecular pathway in which the product of each reaction catalyzes the subsequent reaction.
Permanent cells
Enzyme cascade
glassy to rubbery
hypoxin - angiogenesis
49. You're working on a square polymeric implant of 5cm length and 2mm thick. You've been asked to suggest a precise way to fabricate it - what would you suggest?
Compression molding
Chemotaxis
Polymers - cross linking of polymers
Collagenase
50. The glass transition temperature of a poymer at which a polymer transforms from a ____ state to a ___ state.
glassy to rubbery
Amide
Metals
Permanent cells