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Test your basic knowledge |
Bio Engineering
Start Test
Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Classify the following polymers into appropriate families based on their bond structure i.e. the polymer is an example of poly ____.
negative feedback
Amide
Stress
Heparin
2. The calculation of a polymer's molecular weight (weight average and number number average) is based upon values for ____ and ___.
Positive Feedback
neutrophils - macrophages
Stable cells
Number of polymers - molecular weight of polymer
3. The formation of rust due to corrosion in the body is due to the reaction between these 3 things ____ - ____ - and ____ .
Water - oxygen - metal
Protein Absorption
Allogeneic
heparin
4. During granulation stage of proliferation - growth factors that produce this ____(answer)_____ that function in degrading fibrin and replacing it with collagen.
free radical
autologous
phagocytosis
Proteases
5. Which of polyermization (condensation/free radical) would you choose to obtain a polymer of high molecular weight?
Proteases
Free Radical
Phagocytosis
Hemophilia
6. The trigger for activation of enzymes (anything but endothelial cells!)
Metals
binding
Permanent - replicate
Hemophilia
7. Where are the tissue factors found when they're inactivated
Thrombin
in cytoplasm
Hemocompatibility
phagocytosis
8. Drawback of micromaching
Macrophages
Thrombin
Permanent - replicate
Have to be in a clean room free of dust and biocontamination - expensive
9. Type of fiber drawing that controls details of a polymer by etching on a microscopic level; thus - controlling mechanical properties as well
in cytoplasm
micromachining
stress
Enzyme cascade
10. Disfunction of _____ (cells) producing collagenase during the _____ phase of wound healing may form Keloid scars.
Bioactive
macrophages - proliferation
micromachining
Water - oxygen - metal
11. Cells that proliferate slowly over time (aka liver)
Stable cells
Mast - Collagen
Metals
Higher
12. ____ is a measurement that characterizes the breadth of the distribution of a polymer's molecular weight.
Hemophilia
labile cells
Heparin
Polydesperity index
13. This cleaves into fibrinogen which creates fibrin (a sticky enzyme that allows blood to clot)
Thrombin
cycles
Water - oxygen - metal
hypoxin - angiogenesis
14. Thrombin also activates protein C-- which deactivates earlier factors in the cascade is known as ___ ___.
Permanent - replicate
Proteases
Negative Feedback
Plasticizers
15. ______ Molecular weight degrades slower than lower MW
Hemocompatibility
autologous
Macrophages
Higher
16. The fibrous capsule surrounding a permanent implant is primarily composed of ___ cells and ____ (matrix).
Negative Feedback
Mast - Collagen
Protein Absorption
low
17. No healing of damage neurons is the result of ____ cells that are not able to ____.
Hemocompatibility
Water - oxygen - metal
Enzyme cascade
Permanent - replicate
18. Are polymer additives used to lower glass transition temperature temperature.
Thrombin
hypoxin - angiogenesis
heparin
Plasticizers
19. ____ binds to anti- thrombin III (thrombin inhibitor) and increases its potency 1000- fold.
Heparin
Collagenase/Remodelling
glassy to rubbery
Have to be in a clean room free of dust and biocontamination - expensive
20. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure
photoactive polymers
Damage to cell membranes
Stress
Water
21. In order to produce a blood clot - thrombin cleaves/activates ____ and ____.
heparin
Permanent cells
fibrinogen - factor XIII
Number of polymers - molecular weight of polymer
22. The fatigue limit is value of applied stress below which a material will not fail no matter the number of ____ applied.
stress
Calibration
cycles
Free Radical
23. Resulting from the build up of too much collagen at the surface of injury during the granulation tissue stage of proliferation
Polymers - cross linking of polymers
macrophages - proliferation
Compression molding
scars
24. List two chemical characteristics of polymers:
Permanent cells
Collagenase/Remodelling
Intermolecular bonding - molecular weight
Polymers - cross linking of polymers
25. Activates tissue factors aka endothelial damage
Hemophilia
Compression molding
Negative Feedback
Damage to cell membranes
26. The glass transition temperature of a poymer at which a polymer transforms from a ____ state to a ___ state.
Extrusion
Proteases
glassy to rubbery
Hemocompatibility
27. GPC separates molecules on the basis of size by their passage over a column packed with a porous matrix. ___ molecules pass through the column more quickly.
Large
Higher
labile cells
Allogeneic
28. Deformation that cannot be recovered once the load is removed from the material is ____ deformation.
alloys - passivation
Protein Absorption
Stable cells
Plastic
29. Collagen ____ is responsible for the gradual gain in mechanical properties of wounded tissue between roughly 4 and 52 weeks post- injury.
cross - linking
Extrusion
binding
angiogenesis
30. Condition in which patients can literally bleed to death.
alloys - passivation
Higher
micromachining
Hemophilia
31. Cells that proliferate rapidly (fibroblasts)
binding
Have to be in a clean room free of dust and biocontamination - expensive
labile cells
Regeneration/Repair
32. High conductivity - isotropic - crystalline
Thermoplastics
Metals
Lower
phagocytosis
33. ____ are enzymes responsible for protein degradation.
Proteases
Heparin
Free Radical
Calibration
34. Process that makes long fibers (fiber drawing) by forcing a fluid through an oriface.
Extrusion
Thermoplastics
Proteases
Negative Feedback
35. The process of calibration establishes a quantitative relationship between ____ __ ___ _____ and the direct output of the intstrument (for example time/volume in GPC).
standards of known properties
Lower
Permanent - replicate
stress
36. Essentially all metallic biomaterials are ____ - comprised of two or more metals. One of these metals is selected for its ability to support _____ - the formation of a stable oxide layer that resists further corrosion.
Protein Absorption
Positive Feedback
Thrombin
alloys - passivation
37. Polyethylene oxide grafting to biomaterials was developed to prevent coagulation by interfering with/preventing ___ ___.
Chemotaxis
micromachining
Stable cells
Protein Absorption
38. You're working on a square polymeric implant of 5cm length and 2mm thick. You've been asked to suggest a precise way to fabricate it - what would you suggest?
heparin
Compression molding
Water
Heparin
39. Enzymes (proteins) are not activated only when they are in contact with this type of cells
Polymers - cross linking of polymers
scars
Negative Feedback
Endothelial cells
40. Is directed cell migration in response to a concentration gradient of soluble molecules.
binding
Water - oxygen - metal
labile cells
Chemotaxis
41. Foreign body giants cells are produced by fusion of ___.
Macrophages
micromachining
Damage to cell membranes
Water
42. The two types of white blood cells:
photoactive polymers
Enzyme cascade
Plasticizers
neutrophils - macrophages
43. Relative to free radical polymerization - condensation polymerization generally produces polymer of relatively ____ molecular weight.
low
Chemotaxis
free radical
alloys - passivation
44. Enzyme that really gets the polmerization going!
phagocytosis
cycles
Compression molding
Thrombin
45. _____ establishes a quantitative relationship between measured output values from an instrument and known standards of what is being measured.
Amide
Calibration
hypoxin - angiogenesis
Extrusion
46. Two things needed in the end product of the creation of a scab
chemotaxis
Mast - Collagen
Polymers - cross linking of polymers
alloys - passivation
47. Addition polymerization is commonly initiated by ___ - atoms that have an unpaired electron.
Calibration
phagocytosis
Proteases
free radical
48. A ____ implant is designed to elicit specific - intended to host responses.
Bioactive
Amide
Enzyme cascade
heparin
49. A molecular pathway in which the product of each reaction catalyzes the subsequent reaction.
micromachining
Enzyme cascade
Polydesperity index
Negative Feedback
50. Rather than randomly moving - moves in a directed cell migration manner for specific functions.
glassy to rubbery
chemotaxis
Endothelial cells
Stable cells