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Test your basic knowledge |
Bio Engineering
Start Test
Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Condition in which patients can literally bleed to death.
Hemophilia
Proteases
fibrinogen - factor XIII
Free Radical
2. ____ grafts are derived from the other humans.
Collagenase/Remodelling
Calibration
Allogeneic
Collagenase
3. Which of polyermization (condensation/free radical) would you choose to obtain a polymer of high molecular weight?
in cytoplasm
Free Radical
Permanent cells
stress
4. Damaged cells at the site of injury (mast cells) release ___ (glycosaminoglycan).
Stress
heparin
phagocytosis
alloys - passivation
5. The process of calibration establishes a quantitative relationship between ____ __ ___ _____ and the direct output of the intstrument (for example time/volume in GPC).
Thermoplastics
Protein Absorption
standards of known properties
Hemocompatibility
6. Essentially all metallic biomaterials are ____ - comprised of two or more metals. One of these metals is selected for its ability to support _____ - the formation of a stable oxide layer that resists further corrosion.
micromachining
cross - linking
phagocytosis
alloys - passivation
7. Higher Molecular weight degrades slower than ____ MW
chemotaxis
Lower
fibrinogen - factor XIII
Polymers - cross linking of polymers
8. _____ establishes a quantitative relationship between measured output values from an instrument and known standards of what is being measured.
stress
Calibration
fibrinogen - factor XIII
Negative Feedback
9. The calculation of a polymer's molecular weight (weight average and number number average) is based upon values for ____ and ___.
Damage to cell membranes
Amide
Number of polymers - molecular weight of polymer
free radical
10. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure
Chemotaxis
Thrombin
Positive Feedback
Stress
11. Classify the following polymers into appropriate families based on their bond structure i.e. the polymer is an example of poly ____.
Allogeneic
Compression molding
Metals
Amide
12. The trigger for activation of enzymes (anything but endothelial cells!)
stress
Intermolecular bonding - molecular weight
binding
free radical
13. Enzyme that really gets the polmerization going!
Proteases
macrophages - proliferation
Thrombin
labile cells
14. Disfunction of _____ (cells) producing collagenase during the _____ phase of wound healing may form Keloid scars.
Permanent cells
Mast - Collagen
macrophages - proliferation
Water - oxygen - metal
15. No healing of damage neurons is the result of ____ cells that are not able to ____.
negative feedback
Lower
Endothelial cells
Permanent - replicate
16. This cleaves into fibrinogen which creates fibrin (a sticky enzyme that allows blood to clot)
cycles
negative feedback
Thrombin
Extrusion
17. Is directed cell migration in response to a concentration gradient of soluble molecules.
Positive Feedback
Chemotaxis
photoactive polymers
autologous
18. The fibrous capsule surrounding a permanent implant is primarily composed of ___ cells and ____ (matrix).
Intermolecular bonding - molecular weight
Collagenase
binding
Mast - Collagen
19. Foreign body giants cells are produced by fusion of ___.
Have to be in a clean room free of dust and biocontamination - expensive
Macrophages
Endothelial cells
stress
20. A molecular pathway in which the product of each reaction catalyzes the subsequent reaction.
phagocytosis
Enzyme cascade
alloys - passivation
Endothelial cells
21. Type of fiber drawing that controls details of a polymer by etching on a microscopic level; thus - controlling mechanical properties as well
micromachining
Proteases
cycles
Higher
22. Cells that proliferate rapidly (fibroblasts)
labile cells
Have to be in a clean room free of dust and biocontamination - expensive
Water - oxygen - metal
Enzyme cascade
23. Cells that don't proliferate (neurons)
Free Radical
Macrophages
Permanent cells
Positive Feedback
24. ____ describes the ability of a device to function appropriately in the presence of blood.
Water
mast cells
Hemocompatibility
Calibration
25. ____ binds to anti- thrombin III (thrombin inhibitor) and increases its potency 1000- fold.
neutrophils - macrophages
Enzyme cascade
Heparin
glassy to rubbery
26. Process that makes long fibers (fiber drawing) by forcing a fluid through an oriface.
Extrusion
neutrophils - macrophages
micromachining
Protein Absorption
27. A ____ implant is designed to elicit specific - intended to host responses.
Positive Feedback
Bioactive
Collagenase/Remodelling
Intermolecular bonding - molecular weight
28. Mast cells release this
Positive Feedback
phagocytosis
heparin
Protein Absorption
29. Cells that proliferate slowly over time (aka liver)
Stable cells
Enzyme cascade
glassy to rubbery
chemotaxis
30. Neutrophils remove bacteria/damaged cell debris from a wound site through the process of ___.
phagocytosis
Chemotaxis
Allogeneic
Heparin
31. The fatigue limit is value of applied stress below which a material will not fail no matter the number of ____ applied.
cycles
Stress
Regeneration/Repair
Allogeneic
32. Polyethylene oxide grafting to biomaterials was developed to prevent coagulation by interfering with/preventing ___ ___.
Number of polymers - molecular weight of polymer
fibrinogen - factor XIII
Regeneration/Repair
Protein Absorption
33. Vascular endothelial growth factor is produced in response to ___ and stimulates ___.
Lower
hypoxin - angiogenesis
alloys - passivation
Endothelial cells
34. Resulting from the build up of too much collagen at the surface of injury during the granulation tissue stage of proliferation
Extrusion
Enzyme cascade
Collagenase
scars
35. List two chemical characteristics of polymers:
Damage to cell membranes
hypoxin - angiogenesis
Intermolecular bonding - molecular weight
standards of known properties
36. ____ are enzymes responsible for protein degradation.
Large
Proteases
negative feedback
Stress
37. Keloid scars form due to disfunction of ____.
Proteases
Polydesperity index
alloys - passivation
Collagenase/Remodelling
38. Thrombin also activates protein C-- which deactivates earlier factors in the cascade is known as ___ ___.
Macrophages
Heparin
Negative Feedback
Positive Feedback
39. High conductivity - isotropic - crystalline
heparin
cross - linking
Metals
Have to be in a clean room free of dust and biocontamination - expensive
40. You're working on a square polymeric implant of 5cm length and 2mm thick. You've been asked to suggest a precise way to fabricate it - what would you suggest?
Heparin
Compression molding
in cytoplasm
Free Radical
41. What types of wound healing results from injury with inflammation?
Large
autologous
Stable cells
Regeneration/Repair
42. The formation of rust due to corrosion in the body is due to the reaction between these 3 things ____ - ____ - and ____ .
low
Water - oxygen - metal
Metals
Heparin
43. Cell found in the lining of the blood vessels that release heparin and are a part of the negative feedback system.
heparin
mast cells
Macrophages
fibrinogen - factor XIII
44. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure.
cross - linking
Polydesperity index
stress
Number of polymers - molecular weight of polymer
45. ____ is the process by which cells involved in inflammation internalize and destroy foreign material.
Large
Phagocytosis
Collagenase
heparin
46. Where are the tissue factors found when they're inactivated
in cytoplasm
Phagocytosis
Hemophilia
fibrinogen - factor XIII
47. The glass transition temperature of a poymer at which a polymer transforms from a ____ state to a ___ state.
Hemophilia
stress
Thrombin
glassy to rubbery
48. GPC separates molecules on the basis of size by their passage over a column packed with a porous matrix. ___ molecules pass through the column more quickly.
Plasticizers
Large
neutrophils - macrophages
Amide
49. What type of materials are used for photolithography? (substrate is a silicon wafer - built up material is some _____ ____ )
Heparin
Extrusion
Number of polymers - molecular weight of polymer
photoactive polymers
50. Enzymes (proteins) are not activated only when they are in contact with this type of cells
Lower
Collagenase/Remodelling
free radical
Endothelial cells