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Test your basic knowledge |
Bio Engineering
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Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
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.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. The glass transition temperature of a poymer at which a polymer transforms from a ____ state to a ___ state.
Endothelial cells
fibrinogen - factor XIII
glassy to rubbery
negative feedback
2. Foreign body giants cells are produced by fusion of ___.
Amide
Enzyme cascade
Macrophages
Heparin
3. The trigger for activation of enzymes (anything but endothelial cells!)
macrophages - proliferation
Negative Feedback
Regeneration/Repair
binding
4. Relative to free radical polymerization - condensation polymerization generally produces polymer of relatively ____ molecular weight.
scars
Collagenase
Large
low
5. Collagen ____ is responsible for the gradual gain in mechanical properties of wounded tissue between roughly 4 and 52 weeks post- injury.
Calibration
Bioactive
labile cells
cross - linking
6. Process of producing new blood vessels due to a lack on oxygen and thus inducing VEGF.
Collagenase/Remodelling
Water - oxygen - metal
angiogenesis
heparin
7. The two types of white blood cells:
neutrophils - macrophages
Damage to cell membranes
Compression molding
chemotaxis
8. Cells that don't proliferate (neurons)
Permanent cells
Extrusion
Higher
Plastic
9. Is directed cell migration in response to a concentration gradient of soluble molecules.
photoactive polymers
Chemotaxis
Plasticizers
Protein Absorption
10. Keloid scars form due to disfunction of ____.
Collagenase/Remodelling
Intermolecular bonding - molecular weight
photoactive polymers
Thermoplastics
11. A molecular pathway in which the product of each reaction catalyzes the subsequent reaction.
neutrophils - macrophages
Enzyme cascade
Water - oxygen - metal
Heparin
12. List two chemical characteristics of polymers:
Number of polymers - molecular weight of polymer
Heparin
Intermolecular bonding - molecular weight
Polydesperity index
13. ____ are enzymes responsible for protein degradation.
Negative Feedback
stress
Mast - Collagen
Proteases
14. Where are the tissue factors found when they're inactivated
in cytoplasm
Polymers - cross linking of polymers
Higher
binding
15. Resulting from the build up of too much collagen at the surface of injury during the granulation tissue stage of proliferation
phagocytosis
Hemophilia
Allogeneic
scars
16. GPC separates molecules on the basis of size by their passage over a column packed with a porous matrix. ___ molecules pass through the column more quickly.
Large
Allogeneic
Chemotaxis
Plastic
17. ______ Molecular weight degrades slower than lower MW
Free Radical
Higher
Thrombin
Endothelial cells
18. Two things needed in the end product of the creation of a scab
Polymers - cross linking of polymers
in cytoplasm
Hemophilia
micromachining
19. The formation of rust due to corrosion in the body is due to the reaction between these 3 things ____ - ____ - and ____ .
stress
Water - oxygen - metal
Higher
Regeneration/Repair
20. This type of feedback creates
scars
negative feedback
stress
labile cells
21. Keloid scars forms because disfuntion of
heparin
Stress
Collagenase
Plasticizers
22. ____ is the process by which cells involved in inflammation internalize and destroy foreign material.
Enzyme cascade
Phagocytosis
Stress
Damage to cell membranes
23. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure
Stress
Large
glassy to rubbery
Free Radical
24. A ____ implant is designed to elicit specific - intended to host responses.
Bioactive
Polymers - cross linking of polymers
stress
Hemocompatibility
25. What type of materials are used for photolithography? (substrate is a silicon wafer - built up material is some _____ ____ )
cycles
photoactive polymers
Stable cells
Water
26. Type of fiber drawing that controls details of a polymer by etching on a microscopic level; thus - controlling mechanical properties as well
Proteases
micromachining
Allogeneic
Mast - Collagen
27. ____ binds to anti- thrombin III (thrombin inhibitor) and increases its potency 1000- fold.
Heparin
Permanent cells
phagocytosis
Number of polymers - molecular weight of polymer
28. Cells that proliferate rapidly (fibroblasts)
angiogenesis
labile cells
negative feedback
Permanent cells
29. Cardiac bypass surgery in which a vein from a patient's leg is transplanted to the patient's heart is an example of the us of ____ tissue.
Protein Absorption
Have to be in a clean room free of dust and biocontamination - expensive
autologous
Proteases
30. No healing of damage neurons is the result of ____ cells that are not able to ____.
Stress
binding
autologous
Permanent - replicate
31. What types of wound healing results from injury with inflammation?
neutrophils - macrophages
alloys - passivation
glassy to rubbery
Regeneration/Repair
32. ____ describes the ability of a device to function appropriately in the presence of blood.
Thrombin
Free Radical
Hemocompatibility
Intermolecular bonding - molecular weight
33. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure.
Thrombin
stress
Plastic
Permanent - replicate
34. Enzyme that really gets the polmerization going!
Thrombin
neutrophils - macrophages
Macrophages
cross - linking
35. Essentially all metallic biomaterials are ____ - comprised of two or more metals. One of these metals is selected for its ability to support _____ - the formation of a stable oxide layer that resists further corrosion.
Large
autologous
alloys - passivation
angiogenesis
36. Polyethylene oxide grafting to biomaterials was developed to prevent coagulation by interfering with/preventing ___ ___.
Protein Absorption
Permanent - replicate
Collagenase/Remodelling
in cytoplasm
37. Damaged cells at the site of injury (mast cells) release ___ (glycosaminoglycan).
low
Permanent - replicate
heparin
Macrophages
38. Condition in which patients can literally bleed to death.
Proteases
Stable cells
Hemophilia
Bioactive
39. Drawback of micromaching
Damage to cell membranes
Have to be in a clean room free of dust and biocontamination - expensive
heparin
Permanent - replicate
40. In order to produce a blood clot - thrombin cleaves/activates ____ and ____.
negative feedback
Phagocytosis
fibrinogen - factor XIII
autologous
41. ____ is a measurement that characterizes the breadth of the distribution of a polymer's molecular weight.
Lower
Chemotaxis
Polydesperity index
Proteases
42. The fatigue limit is value of applied stress below which a material will not fail no matter the number of ____ applied.
fibrinogen - factor XIII
low
autologous
cycles
43. Process that makes long fibers (fiber drawing) by forcing a fluid through an oriface.
fibrinogen - factor XIII
Water - oxygen - metal
Extrusion
autologous
44. Disfunction of _____ (cells) producing collagenase during the _____ phase of wound healing may form Keloid scars.
angiogenesis
Negative Feedback
hypoxin - angiogenesis
macrophages - proliferation
45. _____ establishes a quantitative relationship between measured output values from an instrument and known standards of what is being measured.
Mast - Collagen
Calibration
Proteases
Permanent cells
46. Are polymer additives used to lower glass transition temperature temperature.
photoactive polymers
Plasticizers
heparin
Collagenase/Remodelling
47. Activates tissue factors aka endothelial damage
Calibration
angiogenesis
heparin
Damage to cell membranes
48. Mast cells release this
neutrophils - macrophages
glassy to rubbery
heparin
Bioactive
49. The calculation of a polymer's molecular weight (weight average and number number average) is based upon values for ____ and ___.
Polydesperity index
Polymers - cross linking of polymers
Number of polymers - molecular weight of polymer
Proteases
50. You're working on a square polymeric implant of 5cm length and 2mm thick. You've been asked to suggest a precise way to fabricate it - what would you suggest?
Higher
Polydesperity index
Compression molding
alloys - passivation
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