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Test your basic knowledge |
Bio Engineering
Start Test
Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Cell found in the lining of the blood vessels that release heparin and are a part of the negative feedback system.
Damage to cell membranes
Compression molding
mast cells
Macrophages
2. Collagen ____ is responsible for the gradual gain in mechanical properties of wounded tissue between roughly 4 and 52 weeks post- injury.
micromachining
Permanent cells
cross - linking
Allogeneic
3. ____- are polymers that can be repeatedly softened by heating and hardened by cooling.
Endothelial cells
Thermoplastics
micromachining
Proteases
4. Drawback of micromaching
Positive Feedback
Extrusion
Have to be in a clean room free of dust and biocontamination - expensive
Bioactive
5. _____ establishes a quantitative relationship between measured output values from an instrument and known standards of what is being measured.
Negative Feedback
Calibration
Macrophages
Plasticizers
6. ____ are enzymes responsible for protein degradation.
Proteases
glassy to rubbery
Metals
phagocytosis
7. GPC separates molecules on the basis of size by their passage over a column packed with a porous matrix. ___ molecules pass through the column more quickly.
chemotaxis
Permanent cells
Large
free radical
8. Rather than randomly moving - moves in a directed cell migration manner for specific functions.
cycles
Negative Feedback
Stable cells
chemotaxis
9. Damaged cells at the site of injury (mast cells) release ___ (glycosaminoglycan).
hypoxin - angiogenesis
scars
heparin
Allogeneic
10. Which of polyermization (condensation/free radical) would you choose to obtain a polymer of high molecular weight?
Compression molding
Free Radical
Proteases
Water
11. Cells that proliferate slowly over time (aka liver)
Stable cells
photoactive polymers
phagocytosis
Permanent - replicate
12. Foreign body giants cells are produced by fusion of ___.
Water
Macrophages
free radical
Large
13. ____ is a measurement that characterizes the breadth of the distribution of a polymer's molecular weight.
Polydesperity index
Water - oxygen - metal
photoactive polymers
Stress
14. The calculation of a polymer's molecular weight (weight average and number number average) is based upon values for ____ and ___.
labile cells
Calibration
Metals
Number of polymers - molecular weight of polymer
15. Vascular endothelial growth factor is produced in response to ___ and stimulates ___.
Collagenase/Remodelling
stress
Chemotaxis
hypoxin - angiogenesis
16. In order to produce a blood clot - thrombin cleaves/activates ____ and ____.
fibrinogen - factor XIII
standards of known properties
Plasticizers
Heparin
17. Essentially all metallic biomaterials are ____ - comprised of two or more metals. One of these metals is selected for its ability to support _____ - the formation of a stable oxide layer that resists further corrosion.
alloys - passivation
Macrophages
Have to be in a clean room free of dust and biocontamination - expensive
Number of polymers - molecular weight of polymer
18. Process of producing new blood vessels due to a lack on oxygen and thus inducing VEGF.
Bioactive
angiogenesis
Positive Feedback
Macrophages
19. ____ is the process by which cells involved in inflammation internalize and destroy foreign material.
angiogenesis
Bioactive
Metals
Phagocytosis
20. The process of calibration establishes a quantitative relationship between ____ __ ___ _____ and the direct output of the intstrument (for example time/volume in GPC).
Heparin
standards of known properties
phagocytosis
hypoxin - angiogenesis
21. Classify the following polymers into appropriate families based on their bond structure i.e. the polymer is an example of poly ____.
Amide
Number of polymers - molecular weight of polymer
Thrombin
Large
22. A condensation polymerization results with an ester bond between two reactants and this comes off as a result
negative feedback
cross - linking
Water
standards of known properties
23. What type of materials are used for photolithography? (substrate is a silicon wafer - built up material is some _____ ____ )
Heparin
heparin
photoactive polymers
Lower
24. Type of fiber drawing that controls details of a polymer by etching on a microscopic level; thus - controlling mechanical properties as well
Allogeneic
Polymers - cross linking of polymers
micromachining
autologous
25. This type of feedback creates
Chemotaxis
negative feedback
Hemocompatibility
Protein Absorption
26. Disfunction of _____ (cells) producing collagenase during the _____ phase of wound healing may form Keloid scars.
macrophages - proliferation
angiogenesis
Proteases
cycles
27. Cardiac bypass surgery in which a vein from a patient's leg is transplanted to the patient's heart is an example of the us of ____ tissue.
Have to be in a clean room free of dust and biocontamination - expensive
autologous
hypoxin - angiogenesis
Proteases
28. Thrombin also activates protein C-- which deactivates earlier factors in the cascade is known as ___ ___.
Polydesperity index
Enzyme cascade
Collagenase/Remodelling
Negative Feedback
29. Condition in which patients can literally bleed to death.
Hemophilia
cycles
Have to be in a clean room free of dust and biocontamination - expensive
Regeneration/Repair
30. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure
Negative Feedback
Stress
Thrombin
Water - oxygen - metal
31. Where are the tissue factors found when they're inactivated
binding
Bioactive
in cytoplasm
Thermoplastics
32. The two types of white blood cells:
scars
neutrophils - macrophages
Regeneration/Repair
Negative Feedback
33. ____ binds to anti- thrombin III (thrombin inhibitor) and increases its potency 1000- fold.
Permanent cells
Thermoplastics
Heparin
Stable cells
34. Resulting from the build up of too much collagen at the surface of injury during the granulation tissue stage of proliferation
scars
Metals
alloys - passivation
Have to be in a clean room free of dust and biocontamination - expensive
35. Is directed cell migration in response to a concentration gradient of soluble molecules.
Chemotaxis
micromachining
Amide
Stable cells
36. The formation of rust due to corrosion in the body is due to the reaction between these 3 things ____ - ____ - and ____ .
standards of known properties
Water - oxygen - metal
Endothelial cells
neutrophils - macrophages
37. Are polymer additives used to lower glass transition temperature temperature.
Protein Absorption
Plasticizers
Macrophages
stress
38. Cells that proliferate rapidly (fibroblasts)
labile cells
Intermolecular bonding - molecular weight
Thrombin
heparin
39. This cleaves into fibrinogen which creates fibrin (a sticky enzyme that allows blood to clot)
Thrombin
Phagocytosis
Proteases
stress
40. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure.
stress
Polydesperity index
mast cells
Water
41. Relative to free radical polymerization - condensation polymerization generally produces polymer of relatively ____ molecular weight.
Permanent cells
alloys - passivation
low
angiogenesis
42. Enzyme that really gets the polmerization going!
Water - oxygen - metal
standards of known properties
Chemotaxis
Thrombin
43. A ____ implant is designed to elicit specific - intended to host responses.
binding
Bioactive
macrophages - proliferation
Mast - Collagen
44. ______ Molecular weight degrades slower than lower MW
micromachining
Higher
Water
Enzyme cascade
45. No healing of damage neurons is the result of ____ cells that are not able to ____.
neutrophils - macrophages
hypoxin - angiogenesis
Permanent - replicate
Proteases
46. Activates tissue factors aka endothelial damage
Chemotaxis
Endothelial cells
Damage to cell membranes
Negative Feedback
47. The glass transition temperature of a poymer at which a polymer transforms from a ____ state to a ___ state.
fibrinogen - factor XIII
Polymers - cross linking of polymers
Thrombin
glassy to rubbery
48. The fibrous capsule surrounding a permanent implant is primarily composed of ___ cells and ____ (matrix).
Have to be in a clean room free of dust and biocontamination - expensive
Mast - Collagen
Heparin
low
49. Polyethylene oxide grafting to biomaterials was developed to prevent coagulation by interfering with/preventing ___ ___.
Water
Stable cells
Protein Absorption
Large
50. You're working on a square polymeric implant of 5cm length and 2mm thick. You've been asked to suggest a precise way to fabricate it - what would you suggest?
Permanent cells
alloys - passivation
Compression molding
in cytoplasm