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Test your basic knowledge |
Bio Engineering
Start Test
Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Disfunction of _____ (cells) producing collagenase during the _____ phase of wound healing may form Keloid scars.
in cytoplasm
macrophages - proliferation
Thrombin
Large
2. Essentially all metallic biomaterials are ____ - comprised of two or more metals. One of these metals is selected for its ability to support _____ - the formation of a stable oxide layer that resists further corrosion.
alloys - passivation
Stable cells
Thrombin
Plasticizers
3. Damaged cells at the site of injury (mast cells) release ___ (glycosaminoglycan).
Plasticizers
heparin
Water
Stable cells
4. Two things needed in the end product of the creation of a scab
Water - oxygen - metal
Enzyme cascade
Extrusion
Polymers - cross linking of polymers
5. Addition polymerization is commonly initiated by ___ - atoms that have an unpaired electron.
free radical
heparin
Higher
phagocytosis
6. Keloid scars form due to disfunction of ____.
Intermolecular bonding - molecular weight
Have to be in a clean room free of dust and biocontamination - expensive
Collagenase/Remodelling
Thrombin
7. Thrombin also activates protein C-- which deactivates earlier factors in the cascade is known as ___ ___.
standards of known properties
Protein Absorption
Permanent cells
Negative Feedback
8. You're working on a square polymeric implant of 5cm length and 2mm thick. You've been asked to suggest a precise way to fabricate it - what would you suggest?
angiogenesis
Number of polymers - molecular weight of polymer
Thrombin
Compression molding
9. Enzyme that really gets the polmerization going!
Thrombin
Free Radical
Compression molding
cross - linking
10. A ____ implant is designed to elicit specific - intended to host responses.
Bioactive
Hemocompatibility
heparin
Proteases
11. ______ Molecular weight degrades slower than lower MW
Higher
Proteases
Metals
in cytoplasm
12. Vascular endothelial growth factor is produced in response to ___ and stimulates ___.
Collagenase
scars
phagocytosis
hypoxin - angiogenesis
13. Polyethylene oxide grafting to biomaterials was developed to prevent coagulation by interfering with/preventing ___ ___.
Protein Absorption
free radical
binding
Plastic
14. List two chemical characteristics of polymers:
Intermolecular bonding - molecular weight
labile cells
Collagenase/Remodelling
Allogeneic
15. No healing of damage neurons is the result of ____ cells that are not able to ____.
Positive Feedback
negative feedback
Permanent - replicate
Stress
16. ____ is the process by which cells involved in inflammation internalize and destroy foreign material.
Lower
Extrusion
Metals
Phagocytosis
17. In order to produce a blood clot - thrombin cleaves/activates ____ and ____.
Protein Absorption
free radical
Endothelial cells
fibrinogen - factor XIII
18. This cleaves into fibrinogen which creates fibrin (a sticky enzyme that allows blood to clot)
Thrombin
Allogeneic
Endothelial cells
Water - oxygen - metal
19. Process of producing new blood vessels due to a lack on oxygen and thus inducing VEGF.
angiogenesis
Heparin
Damage to cell membranes
Proteases
20. The two types of white blood cells:
neutrophils - macrophages
Polymers - cross linking of polymers
micromachining
autologous
21. The fibrous capsule surrounding a permanent implant is primarily composed of ___ cells and ____ (matrix).
Chemotaxis
Mast - Collagen
Thermoplastics
Number of polymers - molecular weight of polymer
22. The glass transition temperature of a poymer at which a polymer transforms from a ____ state to a ___ state.
Collagenase/Remodelling
glassy to rubbery
Permanent cells
Hemocompatibility
23. Keloid scars forms because disfuntion of
Compression molding
Collagenase
Polymers - cross linking of polymers
low
24. The calculation of a polymer's molecular weight (weight average and number number average) is based upon values for ____ and ___.
Higher
autologous
Stable cells
Number of polymers - molecular weight of polymer
25. Higher Molecular weight degrades slower than ____ MW
photoactive polymers
Plasticizers
Amide
Lower
26. Collagen ____ is responsible for the gradual gain in mechanical properties of wounded tissue between roughly 4 and 52 weeks post- injury.
cross - linking
Proteases
Hemophilia
Amide
27. Classify the following polymers into appropriate families based on their bond structure i.e. the polymer is an example of poly ____.
Amide
Hemophilia
Intermolecular bonding - molecular weight
stress
28. Process that makes long fibers (fiber drawing) by forcing a fluid through an oriface.
Phagocytosis
Polymers - cross linking of polymers
phagocytosis
Extrusion
29. Enzymes (proteins) are not activated only when they are in contact with this type of cells
Endothelial cells
micromachining
Bioactive
Have to be in a clean room free of dust and biocontamination - expensive
30. ____ binds to anti- thrombin III (thrombin inhibitor) and increases its potency 1000- fold.
Proteases
Polydesperity index
Heparin
macrophages - proliferation
31. Drawback of micromaching
Protein Absorption
Chemotaxis
Thrombin
Have to be in a clean room free of dust and biocontamination - expensive
32. Neutrophils remove bacteria/damaged cell debris from a wound site through the process of ___.
Enzyme cascade
Plasticizers
phagocytosis
Regeneration/Repair
33. Resulting from the build up of too much collagen at the surface of injury during the granulation tissue stage of proliferation
in cytoplasm
heparin
scars
stress
34. High conductivity - isotropic - crystalline
Proteases
Large
negative feedback
Metals
35. Which of polyermization (condensation/free radical) would you choose to obtain a polymer of high molecular weight?
Free Radical
Positive Feedback
Protein Absorption
Proteases
36. _____ establishes a quantitative relationship between measured output values from an instrument and known standards of what is being measured.
Calibration
Have to be in a clean room free of dust and biocontamination - expensive
hypoxin - angiogenesis
neutrophils - macrophages
37. ____- are polymers that can be repeatedly softened by heating and hardened by cooling.
Endothelial cells
Thermoplastics
scars
binding
38. Cells that proliferate slowly over time (aka liver)
Stable cells
Allogeneic
Regeneration/Repair
Thrombin
39. Rather than randomly moving - moves in a directed cell migration manner for specific functions.
Water
chemotaxis
Enzyme cascade
Proteases
40. Thrombin activates several upstream factors.
Extrusion
Positive Feedback
Free Radical
in cytoplasm
41. Activates tissue factors aka endothelial damage
Damage to cell membranes
mast cells
heparin
Water - oxygen - metal
42. ____ are enzymes responsible for protein degradation.
Proteases
stress
micromachining
Heparin
43. A condensation polymerization results with an ester bond between two reactants and this comes off as a result
Hemophilia
Stress
Polymers - cross linking of polymers
Water
44. The process of calibration establishes a quantitative relationship between ____ __ ___ _____ and the direct output of the intstrument (for example time/volume in GPC).
Protein Absorption
standards of known properties
Metals
Number of polymers - molecular weight of polymer
45. Cells that don't proliferate (neurons)
binding
glassy to rubbery
angiogenesis
Permanent cells
46. Cells that proliferate rapidly (fibroblasts)
Have to be in a clean room free of dust and biocontamination - expensive
phagocytosis
labile cells
stress
47. ____ is a measurement that characterizes the breadth of the distribution of a polymer's molecular weight.
Stable cells
autologous
cycles
Polydesperity index
48. Type of fiber drawing that controls details of a polymer by etching on a microscopic level; thus - controlling mechanical properties as well
Stress
Collagenase
Water - oxygen - metal
micromachining
49. The fatigue limit is value of applied stress below which a material will not fail no matter the number of ____ applied.
free radical
Proteases
hypoxin - angiogenesis
cycles
50. What types of wound healing results from injury with inflammation?
phagocytosis
Regeneration/Repair
Protein Absorption
Macrophages