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Test your basic knowledge |
Bio Engineering
Start Test
Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. ____ are enzymes responsible for protein degradation.
Proteases
in cytoplasm
Thrombin
angiogenesis
2. ____ binds to anti- thrombin III (thrombin inhibitor) and increases its potency 1000- fold.
Proteases
phagocytosis
Heparin
autologous
3. Resulting from the build up of too much collagen at the surface of injury during the granulation tissue stage of proliferation
scars
chemotaxis
Plastic
Protein Absorption
4. Keloid scars forms because disfuntion of
Collagenase
Protein Absorption
low
cycles
5. Two things needed in the end product of the creation of a scab
Positive Feedback
cross - linking
stress
Polymers - cross linking of polymers
6. Are polymer additives used to lower glass transition temperature temperature.
Plasticizers
Stress
Positive Feedback
Amide
7. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure
Extrusion
Stress
Metals
phagocytosis
8. Polyethylene oxide grafting to biomaterials was developed to prevent coagulation by interfering with/preventing ___ ___.
Polydesperity index
in cytoplasm
angiogenesis
Protein Absorption
9. What types of wound healing results from injury with inflammation?
heparin
Regeneration/Repair
Large
Amide
10. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure.
stress
phagocytosis
Plasticizers
Plastic
11. A condensation polymerization results with an ester bond between two reactants and this comes off as a result
Number of polymers - molecular weight of polymer
Water
alloys - passivation
Positive Feedback
12. Activates tissue factors aka endothelial damage
Damage to cell membranes
Water
hypoxin - angiogenesis
Thermoplastics
13. This cleaves into fibrinogen which creates fibrin (a sticky enzyme that allows blood to clot)
Have to be in a clean room free of dust and biocontamination - expensive
Proteases
Thrombin
neutrophils - macrophages
14. Cells that proliferate rapidly (fibroblasts)
Proteases
scars
low
labile cells
15. Process of producing new blood vessels due to a lack on oxygen and thus inducing VEGF.
Calibration
angiogenesis
Hemophilia
Have to be in a clean room free of dust and biocontamination - expensive
16. Relative to free radical polymerization - condensation polymerization generally produces polymer of relatively ____ molecular weight.
heparin
Free Radical
low
Compression molding
17. During granulation stage of proliferation - growth factors that produce this ____(answer)_____ that function in degrading fibrin and replacing it with collagen.
Proteases
phagocytosis
Endothelial cells
neutrophils - macrophages
18. List two chemical characteristics of polymers:
Free Radical
Thrombin
Intermolecular bonding - molecular weight
Amide
19. Drawback of micromaching
Have to be in a clean room free of dust and biocontamination - expensive
Heparin
Regeneration/Repair
low
20. Is directed cell migration in response to a concentration gradient of soluble molecules.
stress
macrophages - proliferation
Chemotaxis
Proteases
21. ____ is a measurement that characterizes the breadth of the distribution of a polymer's molecular weight.
mast cells
Water - oxygen - metal
autologous
Polydesperity index
22. Mast cells release this
Number of polymers - molecular weight of polymer
heparin
Thrombin
alloys - passivation
23. A molecular pathway in which the product of each reaction catalyzes the subsequent reaction.
macrophages - proliferation
Enzyme cascade
Positive Feedback
glassy to rubbery
24. What type of materials are used for photolithography? (substrate is a silicon wafer - built up material is some _____ ____ )
photoactive polymers
neutrophils - macrophages
binding
Number of polymers - molecular weight of polymer
25. _____ establishes a quantitative relationship between measured output values from an instrument and known standards of what is being measured.
Calibration
Heparin
mast cells
chemotaxis
26. Enzymes (proteins) are not activated only when they are in contact with this type of cells
Endothelial cells
Compression molding
chemotaxis
Free Radical
27. The fatigue limit is value of applied stress below which a material will not fail no matter the number of ____ applied.
Extrusion
Metals
Damage to cell membranes
cycles
28. This type of feedback creates
negative feedback
Stable cells
Enzyme cascade
Extrusion
29. Which of polyermization (condensation/free radical) would you choose to obtain a polymer of high molecular weight?
hypoxin - angiogenesis
Negative Feedback
photoactive polymers
Free Radical
30. The formation of rust due to corrosion in the body is due to the reaction between these 3 things ____ - ____ - and ____ .
Higher
Polydesperity index
Water - oxygen - metal
glassy to rubbery
31. You're working on a square polymeric implant of 5cm length and 2mm thick. You've been asked to suggest a precise way to fabricate it - what would you suggest?
Compression molding
Phagocytosis
Enzyme cascade
low
32. The glass transition temperature of a poymer at which a polymer transforms from a ____ state to a ___ state.
Allogeneic
glassy to rubbery
Permanent cells
Damage to cell membranes
33. ____- are polymers that can be repeatedly softened by heating and hardened by cooling.
Stable cells
Extrusion
Lower
Thermoplastics
34. Thrombin also activates protein C-- which deactivates earlier factors in the cascade is known as ___ ___.
Have to be in a clean room free of dust and biocontamination - expensive
low
Negative Feedback
Phagocytosis
35. ______ Molecular weight degrades slower than lower MW
Number of polymers - molecular weight of polymer
Higher
Permanent - replicate
negative feedback
36. Collagen ____ is responsible for the gradual gain in mechanical properties of wounded tissue between roughly 4 and 52 weeks post- injury.
Compression molding
Hemocompatibility
cross - linking
Heparin
37. In order to produce a blood clot - thrombin cleaves/activates ____ and ____.
fibrinogen - factor XIII
negative feedback
Chemotaxis
heparin
38. GPC separates molecules on the basis of size by their passage over a column packed with a porous matrix. ___ molecules pass through the column more quickly.
Thrombin
Large
Stable cells
Proteases
39. Addition polymerization is commonly initiated by ___ - atoms that have an unpaired electron.
Plasticizers
Bioactive
Chemotaxis
free radical
40. Enzyme that really gets the polmerization going!
Thrombin
Regeneration/Repair
Negative Feedback
Extrusion
41. Rather than randomly moving - moves in a directed cell migration manner for specific functions.
fibrinogen - factor XIII
Proteases
chemotaxis
Macrophages
42. Foreign body giants cells are produced by fusion of ___.
Chemotaxis
free radical
Macrophages
Heparin
43. ____ describes the ability of a device to function appropriately in the presence of blood.
scars
Hemocompatibility
chemotaxis
Mast - Collagen
44. Essentially all metallic biomaterials are ____ - comprised of two or more metals. One of these metals is selected for its ability to support _____ - the formation of a stable oxide layer that resists further corrosion.
Compression molding
Collagenase/Remodelling
heparin
alloys - passivation
45. Higher Molecular weight degrades slower than ____ MW
Lower
Allogeneic
cycles
Enzyme cascade
46. Vascular endothelial growth factor is produced in response to ___ and stimulates ___.
hypoxin - angiogenesis
Collagenase/Remodelling
labile cells
Metals
47. The trigger for activation of enzymes (anything but endothelial cells!)
mast cells
Phagocytosis
binding
Have to be in a clean room free of dust and biocontamination - expensive
48. Keloid scars form due to disfunction of ____.
Hemocompatibility
Chemotaxis
Proteases
Collagenase/Remodelling
49. Process that makes long fibers (fiber drawing) by forcing a fluid through an oriface.
Have to be in a clean room free of dust and biocontamination - expensive
Water
phagocytosis
Extrusion
50. High conductivity - isotropic - crystalline
Metals
labile cells
in cytoplasm
Calibration