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Test your basic knowledge |
Bio Engineering
Start Test
Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Thrombin activates several upstream factors.
Positive Feedback
angiogenesis
Macrophages
Large
2. Cells that proliferate rapidly (fibroblasts)
Number of polymers - molecular weight of polymer
labile cells
Enzyme cascade
Macrophages
3. Cells that don't proliferate (neurons)
Permanent cells
Thrombin
alloys - passivation
Plastic
4. Cells that proliferate slowly over time (aka liver)
Free Radical
alloys - passivation
Stable cells
Bioactive
5. ____ is the process by which cells involved in inflammation internalize and destroy foreign material.
Stable cells
Phagocytosis
Protein Absorption
Water - oxygen - metal
6. Addition polymerization is commonly initiated by ___ - atoms that have an unpaired electron.
free radical
Mast - Collagen
angiogenesis
in cytoplasm
7. List two chemical characteristics of polymers:
Stress
Amide
labile cells
Intermolecular bonding - molecular weight
8. Process of producing new blood vessels due to a lack on oxygen and thus inducing VEGF.
angiogenesis
Collagenase/Remodelling
Regeneration/Repair
Have to be in a clean room free of dust and biocontamination - expensive
9. The process of calibration establishes a quantitative relationship between ____ __ ___ _____ and the direct output of the intstrument (for example time/volume in GPC).
Intermolecular bonding - molecular weight
standards of known properties
Water
Permanent cells
10. The glass transition temperature of a poymer at which a polymer transforms from a ____ state to a ___ state.
Water - oxygen - metal
glassy to rubbery
Stress
Heparin
11. Process that makes long fibers (fiber drawing) by forcing a fluid through an oriface.
Extrusion
Positive Feedback
Permanent - replicate
Thermoplastics
12. Deformation that cannot be recovered once the load is removed from the material is ____ deformation.
heparin
Plastic
hypoxin - angiogenesis
Heparin
13. A condensation polymerization results with an ester bond between two reactants and this comes off as a result
Stable cells
Water
heparin
Hemocompatibility
14. Relative to free radical polymerization - condensation polymerization generally produces polymer of relatively ____ molecular weight.
hypoxin - angiogenesis
in cytoplasm
low
Hemocompatibility
15. ____ describes the ability of a device to function appropriately in the presence of blood.
Hemocompatibility
Calibration
binding
fibrinogen - factor XIII
16. A ____ implant is designed to elicit specific - intended to host responses.
Bioactive
Phagocytosis
Collagenase
Compression molding
17. Which of polyermization (condensation/free radical) would you choose to obtain a polymer of high molecular weight?
Metals
Protein Absorption
Proteases
Free Radical
18. ____- are polymers that can be repeatedly softened by heating and hardened by cooling.
standards of known properties
Amide
fibrinogen - factor XIII
Thermoplastics
19. A molecular pathway in which the product of each reaction catalyzes the subsequent reaction.
stress
Phagocytosis
Bioactive
Enzyme cascade
20. Polyethylene oxide grafting to biomaterials was developed to prevent coagulation by interfering with/preventing ___ ___.
Compression molding
Protein Absorption
Thrombin
scars
21. Cardiac bypass surgery in which a vein from a patient's leg is transplanted to the patient's heart is an example of the us of ____ tissue.
in cytoplasm
Permanent - replicate
autologous
Protein Absorption
22. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure
Stress
Collagenase
macrophages - proliferation
negative feedback
23. Mast cells release this
Protein Absorption
Plastic
heparin
Have to be in a clean room free of dust and biocontamination - expensive
24. During granulation stage of proliferation - growth factors that produce this ____(answer)_____ that function in degrading fibrin and replacing it with collagen.
Negative Feedback
cycles
Proteases
Hemophilia
25. The calculation of a polymer's molecular weight (weight average and number number average) is based upon values for ____ and ___.
Number of polymers - molecular weight of polymer
stress
Free Radical
in cytoplasm
26. Type of fiber drawing that controls details of a polymer by etching on a microscopic level; thus - controlling mechanical properties as well
micromachining
Macrophages
Stress
Chemotaxis
27. Higher Molecular weight degrades slower than ____ MW
Permanent - replicate
Lower
Amide
Collagenase
28. Vascular endothelial growth factor is produced in response to ___ and stimulates ___.
Hemophilia
Intermolecular bonding - molecular weight
standards of known properties
hypoxin - angiogenesis
29. The formation of rust due to corrosion in the body is due to the reaction between these 3 things ____ - ____ - and ____ .
Permanent cells
Intermolecular bonding - molecular weight
standards of known properties
Water - oxygen - metal
30. Thrombin also activates protein C-- which deactivates earlier factors in the cascade is known as ___ ___.
Protein Absorption
Water - oxygen - metal
Negative Feedback
Thermoplastics
31. Collagen ____ is responsible for the gradual gain in mechanical properties of wounded tissue between roughly 4 and 52 weeks post- injury.
Intermolecular bonding - molecular weight
cross - linking
Damage to cell membranes
Chemotaxis
32. GPC separates molecules on the basis of size by their passage over a column packed with a porous matrix. ___ molecules pass through the column more quickly.
heparin
Water - oxygen - metal
in cytoplasm
Large
33. The fatigue limit is value of applied stress below which a material will not fail no matter the number of ____ applied.
cycles
Thrombin
Number of polymers - molecular weight of polymer
Enzyme cascade
34. Keloid scars form due to disfunction of ____.
free radical
Proteases
Phagocytosis
Collagenase/Remodelling
35. Classify the following polymers into appropriate families based on their bond structure i.e. the polymer is an example of poly ____.
Amide
Permanent - replicate
negative feedback
Lower
36. Keloid scars forms because disfuntion of
Stress
Polydesperity index
glassy to rubbery
Collagenase
37. Resulting from the build up of too much collagen at the surface of injury during the granulation tissue stage of proliferation
binding
scars
Calibration
Mast - Collagen
38. Damaged cells at the site of injury (mast cells) release ___ (glycosaminoglycan).
Collagenase/Remodelling
binding
heparin
Endothelial cells
39. Cell found in the lining of the blood vessels that release heparin and are a part of the negative feedback system.
Thrombin
mast cells
Thermoplastics
Macrophages
40. Enzyme that really gets the polmerization going!
Stress
Collagenase
Thrombin
photoactive polymers
41. What type of materials are used for photolithography? (substrate is a silicon wafer - built up material is some _____ ____ )
Collagenase/Remodelling
scars
stress
photoactive polymers
42. This cleaves into fibrinogen which creates fibrin (a sticky enzyme that allows blood to clot)
Stress
Thrombin
Intermolecular bonding - molecular weight
negative feedback
43. Where are the tissue factors found when they're inactivated
Permanent - replicate
in cytoplasm
macrophages - proliferation
Higher
44. Essentially all metallic biomaterials are ____ - comprised of two or more metals. One of these metals is selected for its ability to support _____ - the formation of a stable oxide layer that resists further corrosion.
alloys - passivation
Chemotaxis
phagocytosis
angiogenesis
45. In order to produce a blood clot - thrombin cleaves/activates ____ and ____.
Proteases
Extrusion
Number of polymers - molecular weight of polymer
fibrinogen - factor XIII
46. What types of wound healing results from injury with inflammation?
cross - linking
Polydesperity index
glassy to rubbery
Regeneration/Repair
47. ____ grafts are derived from the other humans.
angiogenesis
phagocytosis
Allogeneic
Permanent cells
48. Enzymes (proteins) are not activated only when they are in contact with this type of cells
neutrophils - macrophages
Endothelial cells
Stable cells
Proteases
49. You're working on a square polymeric implant of 5cm length and 2mm thick. You've been asked to suggest a precise way to fabricate it - what would you suggest?
Compression molding
stress
Permanent cells
Protein Absorption
50. Two things needed in the end product of the creation of a scab
Polymers - cross linking of polymers
heparin
Higher
Intermolecular bonding - molecular weight