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Test your basic knowledge |
Bio Engineering
Start Test
Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Deformation that cannot be recovered once the load is removed from the material is ____ deformation.
Allogeneic
Water
Lower
Plastic
2. ____- are polymers that can be repeatedly softened by heating and hardened by cooling.
alloys - passivation
Plastic
angiogenesis
Thermoplastics
3. A ____ implant is designed to elicit specific - intended to host responses.
Bioactive
neutrophils - macrophages
Positive Feedback
macrophages - proliferation
4. Resulting from the build up of too much collagen at the surface of injury during the granulation tissue stage of proliferation
glassy to rubbery
Stress
Number of polymers - molecular weight of polymer
scars
5. Which of polyermization (condensation/free radical) would you choose to obtain a polymer of high molecular weight?
cross - linking
Free Radical
scars
low
6. What type of materials are used for photolithography? (substrate is a silicon wafer - built up material is some _____ ____ )
Collagenase
photoactive polymers
Permanent cells
Plasticizers
7. ____ is a measurement that characterizes the breadth of the distribution of a polymer's molecular weight.
Allogeneic
Heparin
fibrinogen - factor XIII
Polydesperity index
8. A condensation polymerization results with an ester bond between two reactants and this comes off as a result
Collagenase
Water
autologous
Proteases
9. ____ is the process by which cells involved in inflammation internalize and destroy foreign material.
Bioactive
Heparin
Phagocytosis
Plasticizers
10. Collagen ____ is responsible for the gradual gain in mechanical properties of wounded tissue between roughly 4 and 52 weeks post- injury.
autologous
cross - linking
scars
micromachining
11. Thrombin also activates protein C-- which deactivates earlier factors in the cascade is known as ___ ___.
Thrombin
Higher
stress
Negative Feedback
12. Enzyme that really gets the polmerization going!
cycles
neutrophils - macrophages
Collagenase/Remodelling
Thrombin
13. Are polymer additives used to lower glass transition temperature temperature.
Endothelial cells
Plasticizers
Lower
Regeneration/Repair
14. Keloid scars form due to disfunction of ____.
Calibration
Allogeneic
Collagenase/Remodelling
heparin
15. The formation of rust due to corrosion in the body is due to the reaction between these 3 things ____ - ____ - and ____ .
labile cells
Stress
scars
Water - oxygen - metal
16. You're working on a square polymeric implant of 5cm length and 2mm thick. You've been asked to suggest a precise way to fabricate it - what would you suggest?
Compression molding
glassy to rubbery
Stress
Water
17. Mast cells release this
heparin
Macrophages
Compression molding
low
18. ____ are enzymes responsible for protein degradation.
Higher
labile cells
Proteases
Chemotaxis
19. Cells that don't proliferate (neurons)
free radical
heparin
negative feedback
Permanent cells
20. List two chemical characteristics of polymers:
Chemotaxis
heparin
alloys - passivation
Intermolecular bonding - molecular weight
21. Cell found in the lining of the blood vessels that release heparin and are a part of the negative feedback system.
Metals
neutrophils - macrophages
mast cells
photoactive polymers
22. Type of fiber drawing that controls details of a polymer by etching on a microscopic level; thus - controlling mechanical properties as well
Thrombin
micromachining
Collagenase/Remodelling
Thrombin
23. Drawback of micromaching
Proteases
Have to be in a clean room free of dust and biocontamination - expensive
Water
scars
24. Higher Molecular weight degrades slower than ____ MW
Damage to cell membranes
Permanent cells
Metals
Lower
25. The calculation of a polymer's molecular weight (weight average and number number average) is based upon values for ____ and ___.
Number of polymers - molecular weight of polymer
free radical
Metals
Collagenase
26. ____ binds to anti- thrombin III (thrombin inhibitor) and increases its potency 1000- fold.
labile cells
low
Heparin
Water
27. The trigger for activation of enzymes (anything but endothelial cells!)
binding
Lower
mast cells
Number of polymers - molecular weight of polymer
28. Two things needed in the end product of the creation of a scab
Damage to cell membranes
Polymers - cross linking of polymers
Amide
binding
29. Thrombin activates several upstream factors.
Positive Feedback
Hemocompatibility
cycles
Macrophages
30. The process of calibration establishes a quantitative relationship between ____ __ ___ _____ and the direct output of the intstrument (for example time/volume in GPC).
in cytoplasm
standards of known properties
angiogenesis
Hemocompatibility
31. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure.
Chemotaxis
Bioactive
in cytoplasm
stress
32. Process that makes long fibers (fiber drawing) by forcing a fluid through an oriface.
Extrusion
Macrophages
low
Polymers - cross linking of polymers
33. Relative to free radical polymerization - condensation polymerization generally produces polymer of relatively ____ molecular weight.
low
Polydesperity index
Intermolecular bonding - molecular weight
fibrinogen - factor XIII
34. ______ Molecular weight degrades slower than lower MW
low
binding
standards of known properties
Higher
35. What types of wound healing results from injury with inflammation?
Hemocompatibility
Regeneration/Repair
glassy to rubbery
alloys - passivation
36. Disfunction of _____ (cells) producing collagenase during the _____ phase of wound healing may form Keloid scars.
macrophages - proliferation
glassy to rubbery
Collagenase/Remodelling
Compression molding
37. Neutrophils remove bacteria/damaged cell debris from a wound site through the process of ___.
in cytoplasm
angiogenesis
micromachining
phagocytosis
38. In order to produce a blood clot - thrombin cleaves/activates ____ and ____.
glassy to rubbery
Permanent - replicate
Thermoplastics
fibrinogen - factor XIII
39. This cleaves into fibrinogen which creates fibrin (a sticky enzyme that allows blood to clot)
Endothelial cells
Plasticizers
Thrombin
Positive Feedback
40. During granulation stage of proliferation - growth factors that produce this ____(answer)_____ that function in degrading fibrin and replacing it with collagen.
Lower
negative feedback
Proteases
neutrophils - macrophages
41. The fibrous capsule surrounding a permanent implant is primarily composed of ___ cells and ____ (matrix).
Higher
Mast - Collagen
Polymers - cross linking of polymers
neutrophils - macrophages
42. Essentially all metallic biomaterials are ____ - comprised of two or more metals. One of these metals is selected for its ability to support _____ - the formation of a stable oxide layer that resists further corrosion.
fibrinogen - factor XIII
Hemocompatibility
alloys - passivation
Heparin
43. Damaged cells at the site of injury (mast cells) release ___ (glycosaminoglycan).
heparin
Chemotaxis
chemotaxis
Proteases
44. Classify the following polymers into appropriate families based on their bond structure i.e. the polymer is an example of poly ____.
binding
Amide
Lower
stress
45. Rather than randomly moving - moves in a directed cell migration manner for specific functions.
mast cells
Hemocompatibility
scars
chemotaxis
46. Is directed cell migration in response to a concentration gradient of soluble molecules.
Allogeneic
Negative Feedback
Chemotaxis
Number of polymers - molecular weight of polymer
47. Enzymes (proteins) are not activated only when they are in contact with this type of cells
micromachining
neutrophils - macrophages
low
Endothelial cells
48. ____ describes the ability of a device to function appropriately in the presence of blood.
micromachining
Proteases
Hemocompatibility
heparin
49. Where are the tissue factors found when they're inactivated
fibrinogen - factor XIII
in cytoplasm
Thrombin
labile cells
50. Vascular endothelial growth factor is produced in response to ___ and stimulates ___.
Proteases
Hemophilia
Collagenase/Remodelling
hypoxin - angiogenesis