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Test your basic knowledge |
Bio Engineering
Start Test
Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. You're working on a square polymeric implant of 5cm length and 2mm thick. You've been asked to suggest a precise way to fabricate it - what would you suggest?
Compression molding
phagocytosis
chemotaxis
Positive Feedback
2. Enzymes (proteins) are not activated only when they are in contact with this type of cells
phagocytosis
Thrombin
Endothelial cells
Permanent cells
3. ____- are polymers that can be repeatedly softened by heating and hardened by cooling.
Thermoplastics
Have to be in a clean room free of dust and biocontamination - expensive
stress
mast cells
4. Vascular endothelial growth factor is produced in response to ___ and stimulates ___.
in cytoplasm
cross - linking
Proteases
hypoxin - angiogenesis
5. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure.
alloys - passivation
Heparin
Metals
stress
6. Cardiac bypass surgery in which a vein from a patient's leg is transplanted to the patient's heart is an example of the us of ____ tissue.
autologous
Mast - Collagen
Proteases
Number of polymers - molecular weight of polymer
7. ____ is the process by which cells involved in inflammation internalize and destroy foreign material.
Phagocytosis
angiogenesis
Positive Feedback
Lower
8. Keloid scars forms because disfuntion of
Collagenase
Plastic
Free Radical
Metals
9. Damaged cells at the site of injury (mast cells) release ___ (glycosaminoglycan).
Higher
Proteases
Plastic
heparin
10. During granulation stage of proliferation - growth factors that produce this ____(answer)_____ that function in degrading fibrin and replacing it with collagen.
Proteases
autologous
Collagenase/Remodelling
Higher
11. List two chemical characteristics of polymers:
alloys - passivation
Proteases
Intermolecular bonding - molecular weight
neutrophils - macrophages
12. A ____ implant is designed to elicit specific - intended to host responses.
macrophages - proliferation
Bioactive
Polymers - cross linking of polymers
Stress
13. ____ are enzymes responsible for protein degradation.
Extrusion
Stress
Proteases
chemotaxis
14. Addition polymerization is commonly initiated by ___ - atoms that have an unpaired electron.
Proteases
Damage to cell membranes
Thrombin
free radical
15. Type of fiber drawing that controls details of a polymer by etching on a microscopic level; thus - controlling mechanical properties as well
glassy to rubbery
Enzyme cascade
Hemophilia
micromachining
16. The fatigue limit is value of applied stress below which a material will not fail no matter the number of ____ applied.
Thermoplastics
Proteases
phagocytosis
cycles
17. Keloid scars form due to disfunction of ____.
Higher
Collagenase/Remodelling
low
glassy to rubbery
18. GPC separates molecules on the basis of size by their passage over a column packed with a porous matrix. ___ molecules pass through the column more quickly.
Large
chemotaxis
Proteases
Allogeneic
19. Thrombin also activates protein C-- which deactivates earlier factors in the cascade is known as ___ ___.
photoactive polymers
Positive Feedback
Allogeneic
Negative Feedback
20. ____ is a measurement that characterizes the breadth of the distribution of a polymer's molecular weight.
Polydesperity index
in cytoplasm
autologous
Stress
21. ____ describes the ability of a device to function appropriately in the presence of blood.
Higher
Hemocompatibility
Proteases
Chemotaxis
22. Thrombin activates several upstream factors.
Water - oxygen - metal
Positive Feedback
chemotaxis
free radical
23. Classify the following polymers into appropriate families based on their bond structure i.e. the polymer is an example of poly ____.
Permanent cells
alloys - passivation
Polydesperity index
Amide
24. Deformation that cannot be recovered once the load is removed from the material is ____ deformation.
Plastic
Higher
low
Thrombin
25. Essentially all metallic biomaterials are ____ - comprised of two or more metals. One of these metals is selected for its ability to support _____ - the formation of a stable oxide layer that resists further corrosion.
Macrophages
alloys - passivation
Number of polymers - molecular weight of polymer
Polydesperity index
26. The formation of rust due to corrosion in the body is due to the reaction between these 3 things ____ - ____ - and ____ .
Water - oxygen - metal
scars
Plastic
Compression molding
27. Mast cells release this
heparin
Metals
Hemophilia
stress
28. Foreign body giants cells are produced by fusion of ___.
Metals
glassy to rubbery
Macrophages
Stable cells
29. Resulting from the build up of too much collagen at the surface of injury during the granulation tissue stage of proliferation
stress
macrophages - proliferation
glassy to rubbery
scars
30. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure
Collagenase
Stress
standards of known properties
Thrombin
31. Process that makes long fibers (fiber drawing) by forcing a fluid through an oriface.
Extrusion
Mast - Collagen
Thrombin
Damage to cell membranes
32. ____ binds to anti- thrombin III (thrombin inhibitor) and increases its potency 1000- fold.
Collagenase/Remodelling
Heparin
Water - oxygen - metal
Permanent cells
33. The process of calibration establishes a quantitative relationship between ____ __ ___ _____ and the direct output of the intstrument (for example time/volume in GPC).
cycles
standards of known properties
heparin
Collagenase/Remodelling
34. High conductivity - isotropic - crystalline
Permanent cells
Metals
Thrombin
negative feedback
35. Enzyme that really gets the polmerization going!
mast cells
Thrombin
labile cells
Chemotaxis
36. Collagen ____ is responsible for the gradual gain in mechanical properties of wounded tissue between roughly 4 and 52 weeks post- injury.
standards of known properties
Thrombin
cross - linking
Calibration
37. Activates tissue factors aka endothelial damage
hypoxin - angiogenesis
Free Radical
Mast - Collagen
Damage to cell membranes
38. What types of wound healing results from injury with inflammation?
neutrophils - macrophages
heparin
Regeneration/Repair
Water - oxygen - metal
39. Relative to free radical polymerization - condensation polymerization generally produces polymer of relatively ____ molecular weight.
Heparin
Bioactive
Lower
low
40. Drawback of micromaching
Have to be in a clean room free of dust and biocontamination - expensive
low
Water
heparin
41. The trigger for activation of enzymes (anything but endothelial cells!)
scars
Stress
Thrombin
binding
42. Are polymer additives used to lower glass transition temperature temperature.
hypoxin - angiogenesis
in cytoplasm
Plasticizers
heparin
43. Rather than randomly moving - moves in a directed cell migration manner for specific functions.
chemotaxis
Stable cells
Plasticizers
Collagenase/Remodelling
44. ______ Molecular weight degrades slower than lower MW
Metals
Higher
low
Amide
45. Process of producing new blood vessels due to a lack on oxygen and thus inducing VEGF.
Water - oxygen - metal
angiogenesis
Lower
Calibration
46. ____ grafts are derived from the other humans.
Allogeneic
scars
Enzyme cascade
Water
47. Which of polyermization (condensation/free radical) would you choose to obtain a polymer of high molecular weight?
Free Radical
Plasticizers
alloys - passivation
scars
48. Condition in which patients can literally bleed to death.
phagocytosis
labile cells
Hemophilia
Mast - Collagen
49. No healing of damage neurons is the result of ____ cells that are not able to ____.
Compression molding
Permanent - replicate
Amide
alloys - passivation
50. Disfunction of _____ (cells) producing collagenase during the _____ phase of wound healing may form Keloid scars.
Compression molding
Positive Feedback
cycles
macrophages - proliferation