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Test your basic knowledge |
Bio Engineering
Start Test
Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. List two chemical characteristics of polymers:
Water - oxygen - metal
Intermolecular bonding - molecular weight
Phagocytosis
Extrusion
2. Enzymes (proteins) are not activated only when they are in contact with this type of cells
Endothelial cells
Negative Feedback
Polymers - cross linking of polymers
Polydesperity index
3. Addition polymerization is commonly initiated by ___ - atoms that have an unpaired electron.
Metals
free radical
Compression molding
Permanent cells
4. Enzyme that really gets the polmerization going!
Protein Absorption
Allogeneic
Thrombin
Endothelial cells
5. Keloid scars forms because disfuntion of
mast cells
Protein Absorption
hypoxin - angiogenesis
Collagenase
6. Condition in which patients can literally bleed to death.
Metals
Compression molding
low
Hemophilia
7. Drawback of micromaching
standards of known properties
Enzyme cascade
mast cells
Have to be in a clean room free of dust and biocontamination - expensive
8. Polyethylene oxide grafting to biomaterials was developed to prevent coagulation by interfering with/preventing ___ ___.
Chemotaxis
Thrombin
Protein Absorption
Permanent - replicate
9. The two types of white blood cells:
neutrophils - macrophages
scars
Phagocytosis
Chemotaxis
10. Thrombin also activates protein C-- which deactivates earlier factors in the cascade is known as ___ ___.
Negative Feedback
Amide
autologous
Heparin
11. The fibrous capsule surrounding a permanent implant is primarily composed of ___ cells and ____ (matrix).
Positive Feedback
Proteases
Have to be in a clean room free of dust and biocontamination - expensive
Mast - Collagen
12. _____ establishes a quantitative relationship between measured output values from an instrument and known standards of what is being measured.
Permanent cells
Calibration
Enzyme cascade
photoactive polymers
13. The glass transition temperature of a poymer at which a polymer transforms from a ____ state to a ___ state.
Number of polymers - molecular weight of polymer
glassy to rubbery
Proteases
low
14. Process that makes long fibers (fiber drawing) by forcing a fluid through an oriface.
Extrusion
stress
free radical
Stable cells
15. Deformation that cannot be recovered once the load is removed from the material is ____ deformation.
Collagenase
Collagenase/Remodelling
fibrinogen - factor XIII
Plastic
16. Two things needed in the end product of the creation of a scab
glassy to rubbery
Enzyme cascade
Free Radical
Polymers - cross linking of polymers
17. Are polymer additives used to lower glass transition temperature temperature.
Water
Chemotaxis
Extrusion
Plasticizers
18. Relative to free radical polymerization - condensation polymerization generally produces polymer of relatively ____ molecular weight.
Endothelial cells
low
Thrombin
Compression molding
19. No healing of damage neurons is the result of ____ cells that are not able to ____.
binding
alloys - passivation
Permanent - replicate
angiogenesis
20. Neutrophils remove bacteria/damaged cell debris from a wound site through the process of ___.
stress
Endothelial cells
Intermolecular bonding - molecular weight
phagocytosis
21. Foreign body giants cells are produced by fusion of ___.
Macrophages
Water - oxygen - metal
Damage to cell membranes
Enzyme cascade
22. Classify the following polymers into appropriate families based on their bond structure i.e. the polymer is an example of poly ____.
Amide
Mast - Collagen
Regeneration/Repair
Thermoplastics
23. A molecular pathway in which the product of each reaction catalyzes the subsequent reaction.
Enzyme cascade
Endothelial cells
negative feedback
Protein Absorption
24. Keloid scars form due to disfunction of ____.
Collagenase/Remodelling
Damage to cell membranes
Protein Absorption
Extrusion
25. Disfunction of _____ (cells) producing collagenase during the _____ phase of wound healing may form Keloid scars.
macrophages - proliferation
photoactive polymers
Hemocompatibility
Free Radical
26. Where are the tissue factors found when they're inactivated
Amide
in cytoplasm
Large
Enzyme cascade
27. Process of producing new blood vessels due to a lack on oxygen and thus inducing VEGF.
Collagenase/Remodelling
angiogenesis
autologous
low
28. The trigger for activation of enzymes (anything but endothelial cells!)
Compression molding
Hemophilia
binding
Positive Feedback
29. Damaged cells at the site of injury (mast cells) release ___ (glycosaminoglycan).
Phagocytosis
heparin
negative feedback
Free Radical
30. Type of fiber drawing that controls details of a polymer by etching on a microscopic level; thus - controlling mechanical properties as well
Permanent - replicate
Permanent cells
micromachining
Mast - Collagen
31. Which of polyermization (condensation/free radical) would you choose to obtain a polymer of high molecular weight?
Mast - Collagen
Allogeneic
Free Radical
Metals
32. ____ describes the ability of a device to function appropriately in the presence of blood.
Free Radical
Hemocompatibility
Allogeneic
Proteases
33. A ____ implant is designed to elicit specific - intended to host responses.
Bioactive
fibrinogen - factor XIII
Thrombin
Plasticizers
34. The calculation of a polymer's molecular weight (weight average and number number average) is based upon values for ____ and ___.
Chemotaxis
Calibration
Amide
Number of polymers - molecular weight of polymer
35. Essentially all metallic biomaterials are ____ - comprised of two or more metals. One of these metals is selected for its ability to support _____ - the formation of a stable oxide layer that resists further corrosion.
chemotaxis
Proteases
alloys - passivation
Extrusion
36. ____ grafts are derived from the other humans.
fibrinogen - factor XIII
Mast - Collagen
Allogeneic
autologous
37. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure.
phagocytosis
Mast - Collagen
stress
Extrusion
38. In order to produce a blood clot - thrombin cleaves/activates ____ and ____.
Thrombin
neutrophils - macrophages
fibrinogen - factor XIII
Stress
39. The fatigue limit is value of applied stress below which a material will not fail no matter the number of ____ applied.
Collagenase
phagocytosis
cycles
Hemocompatibility
40. You're working on a square polymeric implant of 5cm length and 2mm thick. You've been asked to suggest a precise way to fabricate it - what would you suggest?
Stable cells
Mast - Collagen
glassy to rubbery
Compression molding
41. Higher Molecular weight degrades slower than ____ MW
Lower
Mast - Collagen
in cytoplasm
macrophages - proliferation
42. Cells that proliferate rapidly (fibroblasts)
labile cells
Regeneration/Repair
Extrusion
Number of polymers - molecular weight of polymer
43. GPC separates molecules on the basis of size by their passage over a column packed with a porous matrix. ___ molecules pass through the column more quickly.
Allogeneic
glassy to rubbery
Large
Positive Feedback
44. This type of feedback creates
Proteases
negative feedback
Polydesperity index
phagocytosis
45. Rather than randomly moving - moves in a directed cell migration manner for specific functions.
Regeneration/Repair
Stress
Bioactive
chemotaxis
46. This cleaves into fibrinogen which creates fibrin (a sticky enzyme that allows blood to clot)
Thrombin
Allogeneic
Polydesperity index
chemotaxis
47. What type of materials are used for photolithography? (substrate is a silicon wafer - built up material is some _____ ____ )
angiogenesis
Phagocytosis
Thrombin
photoactive polymers
48. Thrombin activates several upstream factors.
standards of known properties
Positive Feedback
neutrophils - macrophages
Free Radical
49. Activates tissue factors aka endothelial damage
mast cells
Negative Feedback
phagocytosis
Damage to cell membranes
50. Vascular endothelial growth factor is produced in response to ___ and stimulates ___.
heparin
Collagenase/Remodelling
hypoxin - angiogenesis
Macrophages