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Test your basic knowledge |
Bio Engineering
Start Test
Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Collagen ____ is responsible for the gradual gain in mechanical properties of wounded tissue between roughly 4 and 52 weeks post- injury.
Regeneration/Repair
Extrusion
neutrophils - macrophages
cross - linking
2. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure
Stress
Thrombin
standards of known properties
heparin
3. Is directed cell migration in response to a concentration gradient of soluble molecules.
Chemotaxis
micromachining
Damage to cell membranes
Water
4. The process of calibration establishes a quantitative relationship between ____ __ ___ _____ and the direct output of the intstrument (for example time/volume in GPC).
Have to be in a clean room free of dust and biocontamination - expensive
standards of known properties
heparin
Calibration
5. _____ establishes a quantitative relationship between measured output values from an instrument and known standards of what is being measured.
Have to be in a clean room free of dust and biocontamination - expensive
angiogenesis
Calibration
Regeneration/Repair
6. ____- are polymers that can be repeatedly softened by heating and hardened by cooling.
Thermoplastics
in cytoplasm
Hemocompatibility
Protein Absorption
7. Mast cells release this
negative feedback
Proteases
micromachining
heparin
8. ____ are enzymes responsible for protein degradation.
Proteases
Permanent - replicate
Heparin
macrophages - proliferation
9. The calculation of a polymer's molecular weight (weight average and number number average) is based upon values for ____ and ___.
Hemocompatibility
heparin
mast cells
Number of polymers - molecular weight of polymer
10. High conductivity - isotropic - crystalline
Metals
in cytoplasm
mast cells
photoactive polymers
11. Resulting from the build up of too much collagen at the surface of injury during the granulation tissue stage of proliferation
scars
neutrophils - macrophages
photoactive polymers
Intermolecular bonding - molecular weight
12. Addition polymerization is commonly initiated by ___ - atoms that have an unpaired electron.
Permanent - replicate
Have to be in a clean room free of dust and biocontamination - expensive
free radical
Polymers - cross linking of polymers
13. The trigger for activation of enzymes (anything but endothelial cells!)
chemotaxis
Water
binding
labile cells
14. Activates tissue factors aka endothelial damage
Negative Feedback
Permanent - replicate
Damage to cell membranes
low
15. ____ binds to anti- thrombin III (thrombin inhibitor) and increases its potency 1000- fold.
labile cells
fibrinogen - factor XIII
Heparin
Permanent - replicate
16. ____ is the process by which cells involved in inflammation internalize and destroy foreign material.
Water
Phagocytosis
hypoxin - angiogenesis
negative feedback
17. The glass transition temperature of a poymer at which a polymer transforms from a ____ state to a ___ state.
Compression molding
Permanent cells
Have to be in a clean room free of dust and biocontamination - expensive
glassy to rubbery
18. Damaged cells at the site of injury (mast cells) release ___ (glycosaminoglycan).
heparin
Polymers - cross linking of polymers
Damage to cell membranes
Negative Feedback
19. Classify the following polymers into appropriate families based on their bond structure i.e. the polymer is an example of poly ____.
low
Amide
macrophages - proliferation
stress
20. The formation of rust due to corrosion in the body is due to the reaction between these 3 things ____ - ____ - and ____ .
stress
Positive Feedback
Water - oxygen - metal
Higher
21. In order to produce a blood clot - thrombin cleaves/activates ____ and ____.
Polydesperity index
fibrinogen - factor XIII
Regeneration/Repair
Extrusion
22. Keloid scars form due to disfunction of ____.
Collagenase/Remodelling
free radical
glassy to rubbery
Phagocytosis
23. Neutrophils remove bacteria/damaged cell debris from a wound site through the process of ___.
Polydesperity index
Thrombin
low
phagocytosis
24. Type of fiber drawing that controls details of a polymer by etching on a microscopic level; thus - controlling mechanical properties as well
micromachining
glassy to rubbery
autologous
Protein Absorption
25. You're working on a square polymeric implant of 5cm length and 2mm thick. You've been asked to suggest a precise way to fabricate it - what would you suggest?
phagocytosis
Collagenase
alloys - passivation
Compression molding
26. Rather than randomly moving - moves in a directed cell migration manner for specific functions.
Positive Feedback
mast cells
Phagocytosis
chemotaxis
27. Disfunction of _____ (cells) producing collagenase during the _____ phase of wound healing may form Keloid scars.
Collagenase
macrophages - proliferation
Protein Absorption
autologous
28. A molecular pathway in which the product of each reaction catalyzes the subsequent reaction.
Hemocompatibility
Lower
Water
Enzyme cascade
29. Polyethylene oxide grafting to biomaterials was developed to prevent coagulation by interfering with/preventing ___ ___.
Protein Absorption
Enzyme cascade
cross - linking
photoactive polymers
30. The fibrous capsule surrounding a permanent implant is primarily composed of ___ cells and ____ (matrix).
Protein Absorption
labile cells
Bioactive
Mast - Collagen
31. Thrombin activates several upstream factors.
Proteases
Positive Feedback
Number of polymers - molecular weight of polymer
scars
32. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure.
Intermolecular bonding - molecular weight
Regeneration/Repair
Have to be in a clean room free of dust and biocontamination - expensive
stress
33. ____ describes the ability of a device to function appropriately in the presence of blood.
Hemocompatibility
Phagocytosis
cycles
Number of polymers - molecular weight of polymer
34. A condensation polymerization results with an ester bond between two reactants and this comes off as a result
Endothelial cells
Collagenase/Remodelling
Water
Plasticizers
35. This type of feedback creates
Positive Feedback
negative feedback
alloys - passivation
binding
36. List two chemical characteristics of polymers:
Enzyme cascade
cycles
Intermolecular bonding - molecular weight
Calibration
37. Vascular endothelial growth factor is produced in response to ___ and stimulates ___.
fibrinogen - factor XIII
Hemocompatibility
hypoxin - angiogenesis
Water
38. Cells that don't proliferate (neurons)
Permanent cells
Plastic
Allogeneic
Water - oxygen - metal
39. No healing of damage neurons is the result of ____ cells that are not able to ____.
Permanent - replicate
Water - oxygen - metal
heparin
Thermoplastics
40. Essentially all metallic biomaterials are ____ - comprised of two or more metals. One of these metals is selected for its ability to support _____ - the formation of a stable oxide layer that resists further corrosion.
alloys - passivation
Phagocytosis
Enzyme cascade
Plasticizers
41. The fatigue limit is value of applied stress below which a material will not fail no matter the number of ____ applied.
cross - linking
Chemotaxis
cycles
Phagocytosis
42. Higher Molecular weight degrades slower than ____ MW
Lower
alloys - passivation
Extrusion
heparin
43. Deformation that cannot be recovered once the load is removed from the material is ____ deformation.
Calibration
Thermoplastics
Plastic
Lower
44. Foreign body giants cells are produced by fusion of ___.
Macrophages
Large
Amide
hypoxin - angiogenesis
45. Two things needed in the end product of the creation of a scab
Permanent cells
alloys - passivation
Mast - Collagen
Polymers - cross linking of polymers
46. ____ is a measurement that characterizes the breadth of the distribution of a polymer's molecular weight.
Have to be in a clean room free of dust and biocontamination - expensive
Polydesperity index
Macrophages
binding
47. Cell found in the lining of the blood vessels that release heparin and are a part of the negative feedback system.
Intermolecular bonding - molecular weight
scars
mast cells
Plastic
48. What type of materials are used for photolithography? (substrate is a silicon wafer - built up material is some _____ ____ )
Compression molding
Collagenase/Remodelling
photoactive polymers
binding
49. Which of polyermization (condensation/free radical) would you choose to obtain a polymer of high molecular weight?
mast cells
Free Radical
Hemophilia
Amide
50. This cleaves into fibrinogen which creates fibrin (a sticky enzyme that allows blood to clot)
Thrombin
Macrophages
Endothelial cells
Intermolecular bonding - molecular weight