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Test your basic knowledge |
Bio Engineering
Start Test
Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Disfunction of _____ (cells) producing collagenase during the _____ phase of wound healing may form Keloid scars.
macrophages - proliferation
Calibration
free radical
cycles
2. Collagen ____ is responsible for the gradual gain in mechanical properties of wounded tissue between roughly 4 and 52 weeks post- injury.
cross - linking
Plasticizers
macrophages - proliferation
Compression molding
3. In order to produce a blood clot - thrombin cleaves/activates ____ and ____.
Stable cells
stress
fibrinogen - factor XIII
Phagocytosis
4. GPC separates molecules on the basis of size by their passage over a column packed with a porous matrix. ___ molecules pass through the column more quickly.
Heparin
glassy to rubbery
photoactive polymers
Large
5. The glass transition temperature of a poymer at which a polymer transforms from a ____ state to a ___ state.
Endothelial cells
Hemophilia
heparin
glassy to rubbery
6. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure.
Metals
Free Radical
stress
chemotaxis
7. Two things needed in the end product of the creation of a scab
Protein Absorption
Collagenase
mast cells
Polymers - cross linking of polymers
8. Rather than randomly moving - moves in a directed cell migration manner for specific functions.
chemotaxis
Hemocompatibility
Thermoplastics
in cytoplasm
9. Classify the following polymers into appropriate families based on their bond structure i.e. the polymer is an example of poly ____.
mast cells
glassy to rubbery
Amide
Higher
10. ____ is the process by which cells involved in inflammation internalize and destroy foreign material.
heparin
Proteases
Phagocytosis
autologous
11. Foreign body giants cells are produced by fusion of ___.
phagocytosis
negative feedback
Thrombin
Macrophages
12. ____ is a measurement that characterizes the breadth of the distribution of a polymer's molecular weight.
stress
neutrophils - macrophages
Polydesperity index
Extrusion
13. Condition in which patients can literally bleed to death.
Hemophilia
Collagenase/Remodelling
neutrophils - macrophages
negative feedback
14. ____- are polymers that can be repeatedly softened by heating and hardened by cooling.
Number of polymers - molecular weight of polymer
Bioactive
Thermoplastics
Intermolecular bonding - molecular weight
15. The calculation of a polymer's molecular weight (weight average and number number average) is based upon values for ____ and ___.
low
negative feedback
Number of polymers - molecular weight of polymer
Water - oxygen - metal
16. Activates tissue factors aka endothelial damage
Thermoplastics
Proteases
heparin
Damage to cell membranes
17. Deformation that cannot be recovered once the load is removed from the material is ____ deformation.
Plastic
Amide
low
in cytoplasm
18. Addition polymerization is commonly initiated by ___ - atoms that have an unpaired electron.
Higher
Thrombin
scars
free radical
19. Process that makes long fibers (fiber drawing) by forcing a fluid through an oriface.
free radical
Extrusion
binding
Bioactive
20. Essentially all metallic biomaterials are ____ - comprised of two or more metals. One of these metals is selected for its ability to support _____ - the formation of a stable oxide layer that resists further corrosion.
Hemophilia
Chemotaxis
Damage to cell membranes
alloys - passivation
21. ____ grafts are derived from the other humans.
heparin
Allogeneic
Amide
phagocytosis
22. You're working on a square polymeric implant of 5cm length and 2mm thick. You've been asked to suggest a precise way to fabricate it - what would you suggest?
Permanent cells
Compression molding
Proteases
Water - oxygen - metal
23. Is directed cell migration in response to a concentration gradient of soluble molecules.
Chemotaxis
Amide
in cytoplasm
photoactive polymers
24. Drawback of micromaching
Large
labile cells
Have to be in a clean room free of dust and biocontamination - expensive
low
25. A ____ implant is designed to elicit specific - intended to host responses.
in cytoplasm
Damage to cell membranes
Bioactive
scars
26. What type of materials are used for photolithography? (substrate is a silicon wafer - built up material is some _____ ____ )
Number of polymers - molecular weight of polymer
photoactive polymers
Large
Proteases
27. Neutrophils remove bacteria/damaged cell debris from a wound site through the process of ___.
Thrombin
heparin
heparin
phagocytosis
28. Type of fiber drawing that controls details of a polymer by etching on a microscopic level; thus - controlling mechanical properties as well
Intermolecular bonding - molecular weight
micromachining
Large
autologous
29. Are polymer additives used to lower glass transition temperature temperature.
Amide
hypoxin - angiogenesis
Phagocytosis
Plasticizers
30. This type of feedback creates
hypoxin - angiogenesis
negative feedback
glassy to rubbery
Chemotaxis
31. The process of calibration establishes a quantitative relationship between ____ __ ___ _____ and the direct output of the intstrument (for example time/volume in GPC).
Heparin
fibrinogen - factor XIII
cross - linking
standards of known properties
32. Where are the tissue factors found when they're inactivated
in cytoplasm
Hemophilia
Proteases
chemotaxis
33. Damaged cells at the site of injury (mast cells) release ___ (glycosaminoglycan).
Lower
free radical
heparin
Hemocompatibility
34. Resulting from the build up of too much collagen at the surface of injury during the granulation tissue stage of proliferation
Enzyme cascade
Stable cells
Bioactive
scars
35. This cleaves into fibrinogen which creates fibrin (a sticky enzyme that allows blood to clot)
cycles
Collagenase/Remodelling
Thrombin
micromachining
36. List two chemical characteristics of polymers:
Thrombin
Permanent cells
Permanent - replicate
Intermolecular bonding - molecular weight
37. ____ are enzymes responsible for protein degradation.
Damage to cell membranes
angiogenesis
Proteases
Plastic
38. Mast cells release this
macrophages - proliferation
heparin
Hemophilia
Allogeneic
39. What types of wound healing results from injury with inflammation?
Calibration
Thrombin
Regeneration/Repair
Enzyme cascade
40. Cells that proliferate rapidly (fibroblasts)
phagocytosis
Large
labile cells
Higher
41. The two types of white blood cells:
Higher
Water - oxygen - metal
Hemophilia
neutrophils - macrophages
42. Thrombin also activates protein C-- which deactivates earlier factors in the cascade is known as ___ ___.
hypoxin - angiogenesis
Number of polymers - molecular weight of polymer
photoactive polymers
Negative Feedback
43. The trigger for activation of enzymes (anything but endothelial cells!)
stress
free radical
binding
Number of polymers - molecular weight of polymer
44. Which of polyermization (condensation/free radical) would you choose to obtain a polymer of high molecular weight?
autologous
Free Radical
Bioactive
Positive Feedback
45. Enzyme that really gets the polmerization going!
Stress
Proteases
Thrombin
Collagenase
46. A molecular pathway in which the product of each reaction catalyzes the subsequent reaction.
photoactive polymers
Protein Absorption
Enzyme cascade
Chemotaxis
47. Cells that proliferate slowly over time (aka liver)
Stable cells
Large
Proteases
Enzyme cascade
48. ____ binds to anti- thrombin III (thrombin inhibitor) and increases its potency 1000- fold.
Water - oxygen - metal
Phagocytosis
Stress
Heparin
49. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure
neutrophils - macrophages
Stress
Higher
Number of polymers - molecular weight of polymer
50. Polyethylene oxide grafting to biomaterials was developed to prevent coagulation by interfering with/preventing ___ ___.
Protein Absorption
Damage to cell membranes
Intermolecular bonding - molecular weight
cross - linking