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Test your basic knowledge |
Bio Engineering
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Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. _____ establishes a quantitative relationship between measured output values from an instrument and known standards of what is being measured.
Calibration
Plasticizers
Positive Feedback
Free Radical
2. ____ binds to anti- thrombin III (thrombin inhibitor) and increases its potency 1000- fold.
Lower
photoactive polymers
Heparin
Mast - Collagen
3. Essentially all metallic biomaterials are ____ - comprised of two or more metals. One of these metals is selected for its ability to support _____ - the formation of a stable oxide layer that resists further corrosion.
Regeneration/Repair
Collagenase/Remodelling
Large
alloys - passivation
4. GPC separates molecules on the basis of size by their passage over a column packed with a porous matrix. ___ molecules pass through the column more quickly.
Large
Positive Feedback
fibrinogen - factor XIII
Permanent cells
5. A molecular pathway in which the product of each reaction catalyzes the subsequent reaction.
Plastic
Bioactive
Enzyme cascade
Thermoplastics
6. Which of polyermization (condensation/free radical) would you choose to obtain a polymer of high molecular weight?
photoactive polymers
Macrophages
Thermoplastics
Free Radical
7. Enzyme that really gets the polmerization going!
glassy to rubbery
Protein Absorption
neutrophils - macrophages
Thrombin
8. You're working on a square polymeric implant of 5cm length and 2mm thick. You've been asked to suggest a precise way to fabricate it - what would you suggest?
Compression molding
cross - linking
Intermolecular bonding - molecular weight
heparin
9. A ____ implant is designed to elicit specific - intended to host responses.
Water
Extrusion
Chemotaxis
Bioactive
10. Is directed cell migration in response to a concentration gradient of soluble molecules.
Chemotaxis
Thrombin
Number of polymers - molecular weight of polymer
Water - oxygen - metal
11. ____ is a measurement that characterizes the breadth of the distribution of a polymer's molecular weight.
low
Regeneration/Repair
Endothelial cells
Polydesperity index
12. Damaged cells at the site of injury (mast cells) release ___ (glycosaminoglycan).
Intermolecular bonding - molecular weight
heparin
Stress
Metals
13. What type of materials are used for photolithography? (substrate is a silicon wafer - built up material is some _____ ____ )
photoactive polymers
micromachining
phagocytosis
low
14. The formation of rust due to corrosion in the body is due to the reaction between these 3 things ____ - ____ - and ____ .
micromachining
in cytoplasm
Water - oxygen - metal
Have to be in a clean room free of dust and biocontamination - expensive
15. Two things needed in the end product of the creation of a scab
chemotaxis
Proteases
Polymers - cross linking of polymers
heparin
16. The glass transition temperature of a poymer at which a polymer transforms from a ____ state to a ___ state.
Heparin
Have to be in a clean room free of dust and biocontamination - expensive
glassy to rubbery
Regeneration/Repair
17. The fatigue limit is value of applied stress below which a material will not fail no matter the number of ____ applied.
Bioactive
cycles
Number of polymers - molecular weight of polymer
glassy to rubbery
18. What types of wound healing results from injury with inflammation?
Proteases
Extrusion
Amide
Regeneration/Repair
19. ______ Molecular weight degrades slower than lower MW
Higher
Metals
Negative Feedback
Amide
20. Thrombin also activates protein C-- which deactivates earlier factors in the cascade is known as ___ ___.
Negative Feedback
Collagenase/Remodelling
Chemotaxis
Collagenase
21. ____ is the process by which cells involved in inflammation internalize and destroy foreign material.
chemotaxis
Phagocytosis
Thrombin
Mast - Collagen
22. Addition polymerization is commonly initiated by ___ - atoms that have an unpaired electron.
Phagocytosis
Have to be in a clean room free of dust and biocontamination - expensive
free radical
Metals
23. Collagen ____ is responsible for the gradual gain in mechanical properties of wounded tissue between roughly 4 and 52 weeks post- injury.
cross - linking
cycles
mast cells
Permanent - replicate
24. Enzymes (proteins) are not activated only when they are in contact with this type of cells
binding
photoactive polymers
Endothelial cells
neutrophils - macrophages
25. ____ are enzymes responsible for protein degradation.
low
Amide
Proteases
Polymers - cross linking of polymers
26. The process of calibration establishes a quantitative relationship between ____ __ ___ _____ and the direct output of the intstrument (for example time/volume in GPC).
Amide
Phagocytosis
standards of known properties
Stress
27. Resulting from the build up of too much collagen at the surface of injury during the granulation tissue stage of proliferation
scars
Thrombin
hypoxin - angiogenesis
angiogenesis
28. Drawback of micromaching
Large
Have to be in a clean room free of dust and biocontamination - expensive
heparin
Proteases
29. Cardiac bypass surgery in which a vein from a patient's leg is transplanted to the patient's heart is an example of the us of ____ tissue.
autologous
Protein Absorption
micromachining
Positive Feedback
30. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure.
Proteases
stress
Permanent - replicate
macrophages - proliferation
31. Are polymer additives used to lower glass transition temperature temperature.
Phagocytosis
Plasticizers
Bioactive
Water
32. The fibrous capsule surrounding a permanent implant is primarily composed of ___ cells and ____ (matrix).
Mast - Collagen
standards of known properties
Heparin
Damage to cell membranes
33. Thrombin activates several upstream factors.
Positive Feedback
chemotaxis
angiogenesis
Calibration
34. Keloid scars forms because disfuntion of
photoactive polymers
Water - oxygen - metal
Endothelial cells
Collagenase
35. Type of fiber drawing that controls details of a polymer by etching on a microscopic level; thus - controlling mechanical properties as well
fibrinogen - factor XIII
micromachining
Positive Feedback
Macrophages
36. A condensation polymerization results with an ester bond between two reactants and this comes off as a result
neutrophils - macrophages
Metals
hypoxin - angiogenesis
Water
37. Cells that proliferate rapidly (fibroblasts)
labile cells
negative feedback
Permanent - replicate
Stable cells
38. Keloid scars form due to disfunction of ____.
fibrinogen - factor XIII
Thrombin
Mast - Collagen
Collagenase/Remodelling
39. Mast cells release this
angiogenesis
Proteases
heparin
Large
40. ____- are polymers that can be repeatedly softened by heating and hardened by cooling.
Permanent - replicate
mast cells
Thermoplastics
photoactive polymers
41. Cells that proliferate slowly over time (aka liver)
Metals
Allogeneic
Endothelial cells
Stable cells
42. This type of feedback creates
negative feedback
Regeneration/Repair
heparin
alloys - passivation
43. During granulation stage of proliferation - growth factors that produce this ____(answer)_____ that function in degrading fibrin and replacing it with collagen.
labile cells
stress
Proteases
Hemocompatibility
44. Relative to free radical polymerization - condensation polymerization generally produces polymer of relatively ____ molecular weight.
Chemotaxis
hypoxin - angiogenesis
low
photoactive polymers
45. The calculation of a polymer's molecular weight (weight average and number number average) is based upon values for ____ and ___.
negative feedback
Intermolecular bonding - molecular weight
Number of polymers - molecular weight of polymer
Higher
46. ____ grafts are derived from the other humans.
Allogeneic
negative feedback
Compression molding
scars
47. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure
binding
micromachining
Stress
Macrophages
48. Disfunction of _____ (cells) producing collagenase during the _____ phase of wound healing may form Keloid scars.
Chemotaxis
Proteases
Enzyme cascade
macrophages - proliferation
49. This cleaves into fibrinogen which creates fibrin (a sticky enzyme that allows blood to clot)
Regeneration/Repair
mast cells
Metals
Thrombin
50. Cells that don't proliferate (neurons)
scars
Compression molding
Hemophilia
Permanent cells
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