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Test your basic knowledge |
Bio Engineering
Start Test
Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Where are the tissue factors found when they're inactivated
cross - linking
Permanent cells
Phagocytosis
in cytoplasm
2. ____ is the process by which cells involved in inflammation internalize and destroy foreign material.
autologous
Stable cells
Phagocytosis
heparin
3. Thrombin activates several upstream factors.
Stable cells
Positive Feedback
Macrophages
Metals
4. Cells that proliferate slowly over time (aka liver)
Stable cells
low
cross - linking
Proteases
5. Are polymer additives used to lower glass transition temperature temperature.
Proteases
macrophages - proliferation
mast cells
Plasticizers
6. Polyethylene oxide grafting to biomaterials was developed to prevent coagulation by interfering with/preventing ___ ___.
Compression molding
Intermolecular bonding - molecular weight
Protein Absorption
Polymers - cross linking of polymers
7. The process of calibration establishes a quantitative relationship between ____ __ ___ _____ and the direct output of the intstrument (for example time/volume in GPC).
free radical
Extrusion
Large
standards of known properties
8. A condensation polymerization results with an ester bond between two reactants and this comes off as a result
Chemotaxis
Calibration
Intermolecular bonding - molecular weight
Water
9. Cells that don't proliferate (neurons)
autologous
scars
Permanent cells
Free Radical
10. Resulting from the build up of too much collagen at the surface of injury during the granulation tissue stage of proliferation
Damage to cell membranes
Lower
low
scars
11. What type of materials are used for photolithography? (substrate is a silicon wafer - built up material is some _____ ____ )
Proteases
scars
photoactive polymers
Number of polymers - molecular weight of polymer
12. ______ Molecular weight degrades slower than lower MW
Extrusion
Thrombin
Proteases
Higher
13. Collagen ____ is responsible for the gradual gain in mechanical properties of wounded tissue between roughly 4 and 52 weeks post- injury.
binding
Hemophilia
cross - linking
Thrombin
14. What types of wound healing results from injury with inflammation?
hypoxin - angiogenesis
Regeneration/Repair
autologous
Proteases
15. Is directed cell migration in response to a concentration gradient of soluble molecules.
Permanent cells
Plastic
low
Chemotaxis
16. Which of polyermization (condensation/free radical) would you choose to obtain a polymer of high molecular weight?
autologous
angiogenesis
Free Radical
Amide
17. In order to produce a blood clot - thrombin cleaves/activates ____ and ____.
Intermolecular bonding - molecular weight
fibrinogen - factor XIII
Macrophages
Water
18. Neutrophils remove bacteria/damaged cell debris from a wound site through the process of ___.
phagocytosis
stress
Stable cells
Stress
19. Disfunction of _____ (cells) producing collagenase during the _____ phase of wound healing may form Keloid scars.
macrophages - proliferation
photoactive polymers
in cytoplasm
Large
20. Process that makes long fibers (fiber drawing) by forcing a fluid through an oriface.
glassy to rubbery
Extrusion
alloys - passivation
macrophages - proliferation
21. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure
Compression molding
Polymers - cross linking of polymers
Damage to cell membranes
Stress
22. During granulation stage of proliferation - growth factors that produce this ____(answer)_____ that function in degrading fibrin and replacing it with collagen.
Proteases
glassy to rubbery
labile cells
Hemophilia
23. Process of producing new blood vessels due to a lack on oxygen and thus inducing VEGF.
angiogenesis
Amide
Lower
Water - oxygen - metal
24. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure.
Number of polymers - molecular weight of polymer
Compression molding
Extrusion
stress
25. Condition in which patients can literally bleed to death.
Hemophilia
Collagenase
Higher
photoactive polymers
26. Type of fiber drawing that controls details of a polymer by etching on a microscopic level; thus - controlling mechanical properties as well
micromachining
Calibration
glassy to rubbery
free radical
27. A molecular pathway in which the product of each reaction catalyzes the subsequent reaction.
standards of known properties
Water - oxygen - metal
Enzyme cascade
hypoxin - angiogenesis
28. High conductivity - isotropic - crystalline
Endothelial cells
fibrinogen - factor XIII
Metals
stress
29. ____ grafts are derived from the other humans.
Heparin
chemotaxis
Allogeneic
glassy to rubbery
30. Damaged cells at the site of injury (mast cells) release ___ (glycosaminoglycan).
heparin
Lower
Large
glassy to rubbery
31. The calculation of a polymer's molecular weight (weight average and number number average) is based upon values for ____ and ___.
heparin
cycles
Number of polymers - molecular weight of polymer
Allogeneic
32. List two chemical characteristics of polymers:
Polymers - cross linking of polymers
Proteases
Water
Intermolecular bonding - molecular weight
33. _____ establishes a quantitative relationship between measured output values from an instrument and known standards of what is being measured.
Water
Calibration
free radical
cycles
34. The glass transition temperature of a poymer at which a polymer transforms from a ____ state to a ___ state.
glassy to rubbery
Plasticizers
autologous
phagocytosis
35. Enzymes (proteins) are not activated only when they are in contact with this type of cells
Thrombin
mast cells
Damage to cell membranes
Endothelial cells
36. Deformation that cannot be recovered once the load is removed from the material is ____ deformation.
Proteases
binding
cross - linking
Plastic
37. Drawback of micromaching
Endothelial cells
heparin
Have to be in a clean room free of dust and biocontamination - expensive
Phagocytosis
38. No healing of damage neurons is the result of ____ cells that are not able to ____.
standards of known properties
Water
heparin
Permanent - replicate
39. Mast cells release this
Collagenase
Water - oxygen - metal
heparin
Stress
40. The two types of white blood cells:
Extrusion
Amide
mast cells
neutrophils - macrophages
41. Vascular endothelial growth factor is produced in response to ___ and stimulates ___.
Proteases
Hemophilia
hypoxin - angiogenesis
Stable cells
42. This cleaves into fibrinogen which creates fibrin (a sticky enzyme that allows blood to clot)
Thrombin
Allogeneic
Intermolecular bonding - molecular weight
free radical
43. ____- are polymers that can be repeatedly softened by heating and hardened by cooling.
Thermoplastics
Phagocytosis
glassy to rubbery
standards of known properties
44. You're working on a square polymeric implant of 5cm length and 2mm thick. You've been asked to suggest a precise way to fabricate it - what would you suggest?
Compression molding
cross - linking
Stable cells
chemotaxis
45. The fatigue limit is value of applied stress below which a material will not fail no matter the number of ____ applied.
Enzyme cascade
labile cells
alloys - passivation
cycles
46. Foreign body giants cells are produced by fusion of ___.
Chemotaxis
neutrophils - macrophages
Protein Absorption
Macrophages
47. A ____ implant is designed to elicit specific - intended to host responses.
Bioactive
Plastic
Calibration
stress
48. ____ is a measurement that characterizes the breadth of the distribution of a polymer's molecular weight.
Polydesperity index
hypoxin - angiogenesis
Negative Feedback
Large
49. The trigger for activation of enzymes (anything but endothelial cells!)
binding
Bioactive
phagocytosis
autologous
50. Essentially all metallic biomaterials are ____ - comprised of two or more metals. One of these metals is selected for its ability to support _____ - the formation of a stable oxide layer that resists further corrosion.
low
Free Radical
alloys - passivation
standards of known properties