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Test your basic knowledge |
Bio Engineering
Start Test
Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. The fatigue limit is value of applied stress below which a material will not fail no matter the number of ____ applied.
low
Number of polymers - molecular weight of polymer
Plastic
cycles
2. Higher Molecular weight degrades slower than ____ MW
Intermolecular bonding - molecular weight
Regeneration/Repair
Lower
cycles
3. Collagen ____ is responsible for the gradual gain in mechanical properties of wounded tissue between roughly 4 and 52 weeks post- injury.
scars
low
cross - linking
Extrusion
4. Two things needed in the end product of the creation of a scab
Protein Absorption
Macrophages
Polymers - cross linking of polymers
Plastic
5. Essentially all metallic biomaterials are ____ - comprised of two or more metals. One of these metals is selected for its ability to support _____ - the formation of a stable oxide layer that resists further corrosion.
alloys - passivation
Plasticizers
Heparin
Compression molding
6. The fibrous capsule surrounding a permanent implant is primarily composed of ___ cells and ____ (matrix).
Damage to cell membranes
Mast - Collagen
Regeneration/Repair
Polymers - cross linking of polymers
7. The calculation of a polymer's molecular weight (weight average and number number average) is based upon values for ____ and ___.
free radical
Endothelial cells
Number of polymers - molecular weight of polymer
Hemocompatibility
8. Relative to free radical polymerization - condensation polymerization generally produces polymer of relatively ____ molecular weight.
Metals
standards of known properties
low
stress
9. Is directed cell migration in response to a concentration gradient of soluble molecules.
Chemotaxis
in cytoplasm
free radical
Higher
10. Activates tissue factors aka endothelial damage
free radical
Collagenase/Remodelling
Higher
Damage to cell membranes
11. Mast cells release this
low
Plasticizers
heparin
Large
12. Cell found in the lining of the blood vessels that release heparin and are a part of the negative feedback system.
mast cells
Phagocytosis
Negative Feedback
photoactive polymers
13. Cells that don't proliferate (neurons)
Metals
Collagenase/Remodelling
Permanent cells
Intermolecular bonding - molecular weight
14. List two chemical characteristics of polymers:
Number of polymers - molecular weight of polymer
Chemotaxis
angiogenesis
Intermolecular bonding - molecular weight
15. Keloid scars form due to disfunction of ____.
Polydesperity index
Collagenase/Remodelling
Permanent - replicate
Extrusion
16. A condensation polymerization results with an ester bond between two reactants and this comes off as a result
binding
Water
Number of polymers - molecular weight of polymer
mast cells
17. What types of wound healing results from injury with inflammation?
standards of known properties
angiogenesis
Regeneration/Repair
heparin
18. A molecular pathway in which the product of each reaction catalyzes the subsequent reaction.
Thrombin
Enzyme cascade
Allogeneic
Polydesperity index
19. Enzymes (proteins) are not activated only when they are in contact with this type of cells
cross - linking
Endothelial cells
Chemotaxis
Water - oxygen - metal
20. Process of producing new blood vessels due to a lack on oxygen and thus inducing VEGF.
angiogenesis
chemotaxis
Phagocytosis
in cytoplasm
21. The trigger for activation of enzymes (anything but endothelial cells!)
Amide
Intermolecular bonding - molecular weight
binding
phagocytosis
22. During granulation stage of proliferation - growth factors that produce this ____(answer)_____ that function in degrading fibrin and replacing it with collagen.
angiogenesis
hypoxin - angiogenesis
Proteases
negative feedback
23. ____ are enzymes responsible for protein degradation.
Higher
cycles
Proteases
Phagocytosis
24. ____ is a measurement that characterizes the breadth of the distribution of a polymer's molecular weight.
Have to be in a clean room free of dust and biocontamination - expensive
Amide
Polymers - cross linking of polymers
Polydesperity index
25. This type of feedback creates
standards of known properties
Lower
Thrombin
negative feedback
26. You're working on a square polymeric implant of 5cm length and 2mm thick. You've been asked to suggest a precise way to fabricate it - what would you suggest?
heparin
Compression molding
Chemotaxis
Enzyme cascade
27. Process that makes long fibers (fiber drawing) by forcing a fluid through an oriface.
Extrusion
hypoxin - angiogenesis
heparin
Polymers - cross linking of polymers
28. Are polymer additives used to lower glass transition temperature temperature.
Phagocytosis
Calibration
Plasticizers
Bioactive
29. Foreign body giants cells are produced by fusion of ___.
Polydesperity index
neutrophils - macrophages
Macrophages
low
30. Cells that proliferate rapidly (fibroblasts)
labile cells
Bioactive
Chemotaxis
low
31. Type of fiber drawing that controls details of a polymer by etching on a microscopic level; thus - controlling mechanical properties as well
Mast - Collagen
Amide
labile cells
micromachining
32. ____- are polymers that can be repeatedly softened by heating and hardened by cooling.
Stable cells
Thermoplastics
fibrinogen - factor XIII
autologous
33. ____ binds to anti- thrombin III (thrombin inhibitor) and increases its potency 1000- fold.
Intermolecular bonding - molecular weight
Permanent cells
Heparin
negative feedback
34. Polyethylene oxide grafting to biomaterials was developed to prevent coagulation by interfering with/preventing ___ ___.
Protein Absorption
Compression molding
Bioactive
autologous
35. No healing of damage neurons is the result of ____ cells that are not able to ____.
Permanent cells
Positive Feedback
scars
Permanent - replicate
36. Disfunction of _____ (cells) producing collagenase during the _____ phase of wound healing may form Keloid scars.
macrophages - proliferation
binding
heparin
in cytoplasm
37. Vascular endothelial growth factor is produced in response to ___ and stimulates ___.
Hemocompatibility
standards of known properties
Mast - Collagen
hypoxin - angiogenesis
38. Which of polyermization (condensation/free radical) would you choose to obtain a polymer of high molecular weight?
chemotaxis
Free Radical
Protein Absorption
Compression molding
39. Enzyme that really gets the polmerization going!
Phagocytosis
Have to be in a clean room free of dust and biocontamination - expensive
fibrinogen - factor XIII
Thrombin
40. This cleaves into fibrinogen which creates fibrin (a sticky enzyme that allows blood to clot)
Amide
Large
Collagenase
Thrombin
41. GPC separates molecules on the basis of size by their passage over a column packed with a porous matrix. ___ molecules pass through the column more quickly.
Large
Calibration
Water
Regeneration/Repair
42. Rather than randomly moving - moves in a directed cell migration manner for specific functions.
Extrusion
chemotaxis
Bioactive
scars
43. ____ grafts are derived from the other humans.
Stable cells
Allogeneic
Heparin
Endothelial cells
44. Resulting from the build up of too much collagen at the surface of injury during the granulation tissue stage of proliferation
Enzyme cascade
scars
low
mast cells
45. ____ is the process by which cells involved in inflammation internalize and destroy foreign material.
Permanent - replicate
heparin
Phagocytosis
heparin
46. Cells that proliferate slowly over time (aka liver)
Permanent - replicate
Stress
Heparin
Stable cells
47. Damaged cells at the site of injury (mast cells) release ___ (glycosaminoglycan).
heparin
Plasticizers
Calibration
Thrombin
48. In order to produce a blood clot - thrombin cleaves/activates ____ and ____.
Lower
Calibration
autologous
fibrinogen - factor XIII
49. ______ Molecular weight degrades slower than lower MW
Protein Absorption
labile cells
Higher
Lower
50. What type of materials are used for photolithography? (substrate is a silicon wafer - built up material is some _____ ____ )
heparin
labile cells
photoactive polymers
Polymers - cross linking of polymers