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Test your basic knowledge |
Bio Engineering
Start Test
Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Mast cells release this
heparin
macrophages - proliferation
labile cells
Polymers - cross linking of polymers
2. Relative to free radical polymerization - condensation polymerization generally produces polymer of relatively ____ molecular weight.
standards of known properties
Extrusion
chemotaxis
low
3. The trigger for activation of enzymes (anything but endothelial cells!)
Mast - Collagen
phagocytosis
alloys - passivation
binding
4. ____ binds to anti- thrombin III (thrombin inhibitor) and increases its potency 1000- fold.
Bioactive
Proteases
alloys - passivation
Heparin
5. Activates tissue factors aka endothelial damage
mast cells
Damage to cell membranes
Collagenase/Remodelling
Extrusion
6. Drawback of micromaching
angiogenesis
cycles
Heparin
Have to be in a clean room free of dust and biocontamination - expensive
7. Thrombin also activates protein C-- which deactivates earlier factors in the cascade is known as ___ ___.
Negative Feedback
Protein Absorption
Phagocytosis
Stress
8. Deformation that cannot be recovered once the load is removed from the material is ____ deformation.
Heparin
Plastic
angiogenesis
macrophages - proliferation
9. Resulting from the build up of too much collagen at the surface of injury during the granulation tissue stage of proliferation
scars
Plastic
Macrophages
macrophages - proliferation
10. What type of materials are used for photolithography? (substrate is a silicon wafer - built up material is some _____ ____ )
Higher
photoactive polymers
Regeneration/Repair
Free Radical
11. Classify the following polymers into appropriate families based on their bond structure i.e. the polymer is an example of poly ____.
labile cells
Amide
Hemocompatibility
Endothelial cells
12. Thrombin activates several upstream factors.
Positive Feedback
Stable cells
Polydesperity index
Permanent - replicate
13. Where are the tissue factors found when they're inactivated
Hemocompatibility
Hemophilia
in cytoplasm
Metals
14. Keloid scars form due to disfunction of ____.
Collagenase/Remodelling
chemotaxis
cross - linking
micromachining
15. In order to produce a blood clot - thrombin cleaves/activates ____ and ____.
Mast - Collagen
Extrusion
Chemotaxis
fibrinogen - factor XIII
16. Two things needed in the end product of the creation of a scab
Polymers - cross linking of polymers
glassy to rubbery
Allogeneic
standards of known properties
17. Enzyme that really gets the polmerization going!
Collagenase
Thrombin
neutrophils - macrophages
Compression molding
18. The formation of rust due to corrosion in the body is due to the reaction between these 3 things ____ - ____ - and ____ .
Bioactive
Polydesperity index
negative feedback
Water - oxygen - metal
19. Are polymer additives used to lower glass transition temperature temperature.
Intermolecular bonding - molecular weight
Plasticizers
Phagocytosis
free radical
20. The glass transition temperature of a poymer at which a polymer transforms from a ____ state to a ___ state.
glassy to rubbery
heparin
Thrombin
Damage to cell membranes
21. ____ describes the ability of a device to function appropriately in the presence of blood.
Enzyme cascade
Number of polymers - molecular weight of polymer
Calibration
Hemocompatibility
22. Is directed cell migration in response to a concentration gradient of soluble molecules.
Chemotaxis
neutrophils - macrophages
Intermolecular bonding - molecular weight
Phagocytosis
23. Cardiac bypass surgery in which a vein from a patient's leg is transplanted to the patient's heart is an example of the us of ____ tissue.
heparin
Compression molding
hypoxin - angiogenesis
autologous
24. Disfunction of _____ (cells) producing collagenase during the _____ phase of wound healing may form Keloid scars.
phagocytosis
labile cells
macrophages - proliferation
Plastic
25. ____ is the process by which cells involved in inflammation internalize and destroy foreign material.
stress
Phagocytosis
binding
Stable cells
26. Polyethylene oxide grafting to biomaterials was developed to prevent coagulation by interfering with/preventing ___ ___.
in cytoplasm
Enzyme cascade
Protein Absorption
Polydesperity index
27. Collagen ____ is responsible for the gradual gain in mechanical properties of wounded tissue between roughly 4 and 52 weeks post- injury.
Mast - Collagen
negative feedback
cross - linking
Allogeneic
28. GPC separates molecules on the basis of size by their passage over a column packed with a porous matrix. ___ molecules pass through the column more quickly.
Polymers - cross linking of polymers
fibrinogen - factor XIII
Enzyme cascade
Large
29. The process of calibration establishes a quantitative relationship between ____ __ ___ _____ and the direct output of the intstrument (for example time/volume in GPC).
Have to be in a clean room free of dust and biocontamination - expensive
standards of known properties
Amide
Proteases
30. During granulation stage of proliferation - growth factors that produce this ____(answer)_____ that function in degrading fibrin and replacing it with collagen.
Have to be in a clean room free of dust and biocontamination - expensive
Proteases
Enzyme cascade
Allogeneic
31. Cell found in the lining of the blood vessels that release heparin and are a part of the negative feedback system.
Hemocompatibility
Intermolecular bonding - molecular weight
Polydesperity index
mast cells
32. List two chemical characteristics of polymers:
Free Radical
binding
in cytoplasm
Intermolecular bonding - molecular weight
33. Rather than randomly moving - moves in a directed cell migration manner for specific functions.
chemotaxis
autologous
Intermolecular bonding - molecular weight
Number of polymers - molecular weight of polymer
34. Process of producing new blood vessels due to a lack on oxygen and thus inducing VEGF.
Thrombin
Large
angiogenesis
Stable cells
35. _____ establishes a quantitative relationship between measured output values from an instrument and known standards of what is being measured.
Proteases
Collagenase
Calibration
angiogenesis
36. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure.
glassy to rubbery
Thermoplastics
stress
cycles
37. Foreign body giants cells are produced by fusion of ___.
Macrophages
Phagocytosis
Water - oxygen - metal
binding
38. The two types of white blood cells:
Plastic
neutrophils - macrophages
standards of known properties
heparin
39. ____ is a measurement that characterizes the breadth of the distribution of a polymer's molecular weight.
Permanent cells
in cytoplasm
Polydesperity index
binding
40. This cleaves into fibrinogen which creates fibrin (a sticky enzyme that allows blood to clot)
Calibration
Water - oxygen - metal
Thrombin
Permanent cells
41. ____ grafts are derived from the other humans.
Polydesperity index
Polymers - cross linking of polymers
Allogeneic
Hemocompatibility
42. ______ Molecular weight degrades slower than lower MW
Free Radical
Have to be in a clean room free of dust and biocontamination - expensive
Water
Higher
43. A molecular pathway in which the product of each reaction catalyzes the subsequent reaction.
Enzyme cascade
Free Radical
scars
autologous
44. The fatigue limit is value of applied stress below which a material will not fail no matter the number of ____ applied.
Collagenase/Remodelling
neutrophils - macrophages
hypoxin - angiogenesis
cycles
45. No healing of damage neurons is the result of ____ cells that are not able to ____.
Stress
Damage to cell membranes
Permanent - replicate
Stable cells
46. ____ are enzymes responsible for protein degradation.
micromachining
binding
Mast - Collagen
Proteases
47. Keloid scars forms because disfuntion of
Chemotaxis
Heparin
Collagenase
Large
48. You're working on a square polymeric implant of 5cm length and 2mm thick. You've been asked to suggest a precise way to fabricate it - what would you suggest?
Compression molding
autologous
Amide
Hemocompatibility
49. Essentially all metallic biomaterials are ____ - comprised of two or more metals. One of these metals is selected for its ability to support _____ - the formation of a stable oxide layer that resists further corrosion.
alloys - passivation
Water
micromachining
Lower
50. The calculation of a polymer's molecular weight (weight average and number number average) is based upon values for ____ and ___.
cross - linking
Hemocompatibility
Amide
Number of polymers - molecular weight of polymer