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Test your basic knowledge |
Bio Engineering
Start Test
Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Cells that proliferate slowly over time (aka liver)
Stable cells
Plasticizers
angiogenesis
neutrophils - macrophages
2. The fibrous capsule surrounding a permanent implant is primarily composed of ___ cells and ____ (matrix).
Collagenase
Mast - Collagen
Higher
alloys - passivation
3. ____ is the process by which cells involved in inflammation internalize and destroy foreign material.
Lower
Large
Endothelial cells
Phagocytosis
4. Mast cells release this
Bioactive
Phagocytosis
heparin
Enzyme cascade
5. Enzyme that really gets the polmerization going!
cross - linking
Free Radical
Phagocytosis
Thrombin
6. The glass transition temperature of a poymer at which a polymer transforms from a ____ state to a ___ state.
Collagenase
Lower
fibrinogen - factor XIII
glassy to rubbery
7. Process of producing new blood vessels due to a lack on oxygen and thus inducing VEGF.
glassy to rubbery
angiogenesis
Thrombin
cycles
8. Rather than randomly moving - moves in a directed cell migration manner for specific functions.
chemotaxis
Extrusion
Plasticizers
Proteases
9. List two chemical characteristics of polymers:
Intermolecular bonding - molecular weight
Plasticizers
autologous
Endothelial cells
10. The two types of white blood cells:
Enzyme cascade
Proteases
Amide
neutrophils - macrophages
11. Addition polymerization is commonly initiated by ___ - atoms that have an unpaired electron.
Metals
Enzyme cascade
Higher
free radical
12. Enzymes (proteins) are not activated only when they are in contact with this type of cells
Endothelial cells
Polydesperity index
Allogeneic
scars
13. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure.
stress
in cytoplasm
standards of known properties
Free Radical
14. Cells that proliferate rapidly (fibroblasts)
neutrophils - macrophages
free radical
labile cells
glassy to rubbery
15. Process that makes long fibers (fiber drawing) by forcing a fluid through an oriface.
Macrophages
Positive Feedback
Higher
Extrusion
16. Higher Molecular weight degrades slower than ____ MW
Lower
heparin
Regeneration/Repair
Plasticizers
17. Condition in which patients can literally bleed to death.
Hemophilia
mast cells
Macrophages
Stress
18. Drawback of micromaching
Allogeneic
Polydesperity index
Proteases
Have to be in a clean room free of dust and biocontamination - expensive
19. Two things needed in the end product of the creation of a scab
Extrusion
macrophages - proliferation
Number of polymers - molecular weight of polymer
Polymers - cross linking of polymers
20. ____ describes the ability of a device to function appropriately in the presence of blood.
alloys - passivation
chemotaxis
Hemocompatibility
Number of polymers - molecular weight of polymer
21. ____ grafts are derived from the other humans.
binding
Plasticizers
fibrinogen - factor XIII
Allogeneic
22. The trigger for activation of enzymes (anything but endothelial cells!)
Plasticizers
Higher
Number of polymers - molecular weight of polymer
binding
23. No healing of damage neurons is the result of ____ cells that are not able to ____.
Endothelial cells
stress
Damage to cell membranes
Permanent - replicate
24. Damaged cells at the site of injury (mast cells) release ___ (glycosaminoglycan).
heparin
Permanent cells
mast cells
glassy to rubbery
25. Keloid scars form due to disfunction of ____.
Stable cells
Large
Collagenase/Remodelling
Collagenase
26. Where are the tissue factors found when they're inactivated
in cytoplasm
Bioactive
Mast - Collagen
negative feedback
27. Polyethylene oxide grafting to biomaterials was developed to prevent coagulation by interfering with/preventing ___ ___.
chemotaxis
cycles
Stable cells
Protein Absorption
28. What type of materials are used for photolithography? (substrate is a silicon wafer - built up material is some _____ ____ )
photoactive polymers
Calibration
labile cells
Amide
29. In order to produce a blood clot - thrombin cleaves/activates ____ and ____.
Permanent cells
Allogeneic
autologous
fibrinogen - factor XIII
30. ____- are polymers that can be repeatedly softened by heating and hardened by cooling.
Compression molding
Thermoplastics
Negative Feedback
in cytoplasm
31. This cleaves into fibrinogen which creates fibrin (a sticky enzyme that allows blood to clot)
Free Radical
Thrombin
Stress
Large
32. Disfunction of _____ (cells) producing collagenase during the _____ phase of wound healing may form Keloid scars.
Lower
micromachining
Damage to cell membranes
macrophages - proliferation
33. The calculation of a polymer's molecular weight (weight average and number number average) is based upon values for ____ and ___.
Polydesperity index
Number of polymers - molecular weight of polymer
Stable cells
Metals
34. A ____ implant is designed to elicit specific - intended to host responses.
Bioactive
labile cells
micromachining
scars
35. ____ binds to anti- thrombin III (thrombin inhibitor) and increases its potency 1000- fold.
Macrophages
Thrombin
Heparin
Thrombin
36. The formation of rust due to corrosion in the body is due to the reaction between these 3 things ____ - ____ - and ____ .
Hemophilia
Water - oxygen - metal
hypoxin - angiogenesis
labile cells
37. Essentially all metallic biomaterials are ____ - comprised of two or more metals. One of these metals is selected for its ability to support _____ - the formation of a stable oxide layer that resists further corrosion.
low
Extrusion
Mast - Collagen
alloys - passivation
38. This type of feedback creates
negative feedback
Extrusion
mast cells
Free Radical
39. Type of fiber drawing that controls details of a polymer by etching on a microscopic level; thus - controlling mechanical properties as well
fibrinogen - factor XIII
micromachining
cross - linking
Polydesperity index
40. Classify the following polymers into appropriate families based on their bond structure i.e. the polymer is an example of poly ____.
Endothelial cells
Permanent - replicate
Amide
Regeneration/Repair
41. _____ establishes a quantitative relationship between measured output values from an instrument and known standards of what is being measured.
heparin
Mast - Collagen
cross - linking
Calibration
42. Foreign body giants cells are produced by fusion of ___.
Macrophages
Permanent - replicate
Endothelial cells
Heparin
43. Resulting from the build up of too much collagen at the surface of injury during the granulation tissue stage of proliferation
scars
Macrophages
Positive Feedback
Mast - Collagen
44. What types of wound healing results from injury with inflammation?
Polydesperity index
stress
Intermolecular bonding - molecular weight
Regeneration/Repair
45. Which of polyermization (condensation/free radical) would you choose to obtain a polymer of high molecular weight?
Free Radical
hypoxin - angiogenesis
photoactive polymers
Hemocompatibility
46. ____ are enzymes responsible for protein degradation.
binding
hypoxin - angiogenesis
Proteases
Thermoplastics
47. Vascular endothelial growth factor is produced in response to ___ and stimulates ___.
Thrombin
labile cells
hypoxin - angiogenesis
chemotaxis
48. Are polymer additives used to lower glass transition temperature temperature.
Hemocompatibility
Bioactive
Thrombin
Plasticizers
49. You're working on a square polymeric implant of 5cm length and 2mm thick. You've been asked to suggest a precise way to fabricate it - what would you suggest?
chemotaxis
Compression molding
phagocytosis
autologous
50. Thrombin activates several upstream factors.
micromachining
Positive Feedback
negative feedback
Macrophages