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Test your basic knowledge |
Bio Engineering
Start Test
Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Is directed cell migration in response to a concentration gradient of soluble molecules.
Free Radical
Chemotaxis
Hemophilia
Extrusion
2. Where are the tissue factors found when they're inactivated
chemotaxis
in cytoplasm
Protein Absorption
Permanent - replicate
3. This type of feedback creates
Thrombin
standards of known properties
Heparin
negative feedback
4. Mast cells release this
Higher
Hemophilia
Stress
heparin
5. The trigger for activation of enzymes (anything but endothelial cells!)
Thrombin
photoactive polymers
binding
standards of known properties
6. Activates tissue factors aka endothelial damage
Damage to cell membranes
Extrusion
binding
Plastic
7. GPC separates molecules on the basis of size by their passage over a column packed with a porous matrix. ___ molecules pass through the column more quickly.
Thrombin
Proteases
neutrophils - macrophages
Large
8. Cells that proliferate rapidly (fibroblasts)
labile cells
scars
autologous
Regeneration/Repair
9. ____ describes the ability of a device to function appropriately in the presence of blood.
Hemocompatibility
Bioactive
Allogeneic
Thrombin
10. The fibrous capsule surrounding a permanent implant is primarily composed of ___ cells and ____ (matrix).
Mast - Collagen
Hemophilia
heparin
scars
11. Enzymes (proteins) are not activated only when they are in contact with this type of cells
in cytoplasm
negative feedback
Heparin
Endothelial cells
12. Thrombin also activates protein C-- which deactivates earlier factors in the cascade is known as ___ ___.
Negative Feedback
scars
Collagenase
Phagocytosis
13. Keloid scars forms because disfuntion of
Positive Feedback
Collagenase
Calibration
mast cells
14. Disfunction of _____ (cells) producing collagenase during the _____ phase of wound healing may form Keloid scars.
macrophages - proliferation
Amide
Plasticizers
Polydesperity index
15. The formation of rust due to corrosion in the body is due to the reaction between these 3 things ____ - ____ - and ____ .
mast cells
Thrombin
Water - oxygen - metal
Permanent cells
16. Addition polymerization is commonly initiated by ___ - atoms that have an unpaired electron.
free radical
Polymers - cross linking of polymers
Proteases
photoactive polymers
17. Cell found in the lining of the blood vessels that release heparin and are a part of the negative feedback system.
Negative Feedback
mast cells
low
Permanent - replicate
18. Are polymer additives used to lower glass transition temperature temperature.
mast cells
Free Radical
Plasticizers
Stable cells
19. ____ is a measurement that characterizes the breadth of the distribution of a polymer's molecular weight.
Damage to cell membranes
Thrombin
Allogeneic
Polydesperity index
20. A ____ implant is designed to elicit specific - intended to host responses.
Protein Absorption
Compression molding
in cytoplasm
Bioactive
21. The two types of white blood cells:
heparin
neutrophils - macrophages
Compression molding
cross - linking
22. Foreign body giants cells are produced by fusion of ___.
Macrophages
Lower
in cytoplasm
hypoxin - angiogenesis
23. A condensation polymerization results with an ester bond between two reactants and this comes off as a result
Stress
negative feedback
Water
Hemophilia
24. _____ establishes a quantitative relationship between measured output values from an instrument and known standards of what is being measured.
Thrombin
heparin
Phagocytosis
Calibration
25. This cleaves into fibrinogen which creates fibrin (a sticky enzyme that allows blood to clot)
phagocytosis
Allogeneic
Thrombin
binding
26. ______ Molecular weight degrades slower than lower MW
Higher
cycles
Large
labile cells
27. Thrombin activates several upstream factors.
Number of polymers - molecular weight of polymer
Hemophilia
Polymers - cross linking of polymers
Positive Feedback
28. Classify the following polymers into appropriate families based on their bond structure i.e. the polymer is an example of poly ____.
autologous
cross - linking
Amide
Polydesperity index
29. Deformation that cannot be recovered once the load is removed from the material is ____ deformation.
Plastic
Permanent - replicate
Macrophages
Free Radical
30. Keloid scars form due to disfunction of ____.
heparin
Collagenase/Remodelling
Regeneration/Repair
Stress
31. ____ grafts are derived from the other humans.
Allogeneic
Bioactive
Thrombin
Regeneration/Repair
32. Relative to free radical polymerization - condensation polymerization generally produces polymer of relatively ____ molecular weight.
Number of polymers - molecular weight of polymer
Phagocytosis
low
Amide
33. ____ are enzymes responsible for protein degradation.
stress
macrophages - proliferation
low
Proteases
34. Resulting from the build up of too much collagen at the surface of injury during the granulation tissue stage of proliferation
Calibration
scars
micromachining
cycles
35. Process that makes long fibers (fiber drawing) by forcing a fluid through an oriface.
labile cells
Polydesperity index
Extrusion
Bioactive
36. During granulation stage of proliferation - growth factors that produce this ____(answer)_____ that function in degrading fibrin and replacing it with collagen.
Polymers - cross linking of polymers
Stable cells
Number of polymers - molecular weight of polymer
Proteases
37. What types of wound healing results from injury with inflammation?
Have to be in a clean room free of dust and biocontamination - expensive
Regeneration/Repair
alloys - passivation
stress
38. A molecular pathway in which the product of each reaction catalyzes the subsequent reaction.
Higher
Enzyme cascade
macrophages - proliferation
Compression molding
39. Cells that proliferate slowly over time (aka liver)
Enzyme cascade
Stable cells
Mast - Collagen
Lower
40. Rather than randomly moving - moves in a directed cell migration manner for specific functions.
chemotaxis
angiogenesis
cross - linking
in cytoplasm
41. ____- are polymers that can be repeatedly softened by heating and hardened by cooling.
standards of known properties
scars
fibrinogen - factor XIII
Thermoplastics
42. You're working on a square polymeric implant of 5cm length and 2mm thick. You've been asked to suggest a precise way to fabricate it - what would you suggest?
low
binding
Compression molding
Permanent cells
43. Which of polyermization (condensation/free radical) would you choose to obtain a polymer of high molecular weight?
Heparin
Stress
low
Free Radical
44. List two chemical characteristics of polymers:
negative feedback
Regeneration/Repair
labile cells
Intermolecular bonding - molecular weight
45. Type of fiber drawing that controls details of a polymer by etching on a microscopic level; thus - controlling mechanical properties as well
micromachining
angiogenesis
standards of known properties
Macrophages
46. Damaged cells at the site of injury (mast cells) release ___ (glycosaminoglycan).
Thrombin
heparin
Regeneration/Repair
in cytoplasm
47. Collagen ____ is responsible for the gradual gain in mechanical properties of wounded tissue between roughly 4 and 52 weeks post- injury.
phagocytosis
negative feedback
Protein Absorption
cross - linking
48. Condition in which patients can literally bleed to death.
Large
Thrombin
Hemophilia
Have to be in a clean room free of dust and biocontamination - expensive
49. Essentially all metallic biomaterials are ____ - comprised of two or more metals. One of these metals is selected for its ability to support _____ - the formation of a stable oxide layer that resists further corrosion.
Enzyme cascade
Hemophilia
Damage to cell membranes
alloys - passivation
50. Two things needed in the end product of the creation of a scab
fibrinogen - factor XIII
stress
Endothelial cells
Polymers - cross linking of polymers