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Bio Engineering
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Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Vascular endothelial growth factor is produced in response to ___ and stimulates ___.
hypoxin - angiogenesis
Regeneration/Repair
Polydesperity index
Polymers - cross linking of polymers
2. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure.
macrophages - proliferation
glassy to rubbery
Number of polymers - molecular weight of polymer
stress
3. No healing of damage neurons is the result of ____ cells that are not able to ____.
binding
Polymers - cross linking of polymers
Permanent - replicate
angiogenesis
4. List two chemical characteristics of polymers:
Thermoplastics
Intermolecular bonding - molecular weight
Stable cells
Bioactive
5. What types of wound healing results from injury with inflammation?
Compression molding
labile cells
Regeneration/Repair
Polymers - cross linking of polymers
6. High conductivity - isotropic - crystalline
mast cells
heparin
Metals
hypoxin - angiogenesis
7. Deformation that cannot be recovered once the load is removed from the material is ____ deformation.
autologous
Chemotaxis
heparin
Plastic
8. Are polymer additives used to lower glass transition temperature temperature.
cross - linking
Plasticizers
Macrophages
stress
9. Process that makes long fibers (fiber drawing) by forcing a fluid through an oriface.
Extrusion
Negative Feedback
Polydesperity index
micromachining
10. Where are the tissue factors found when they're inactivated
Thrombin
Water
in cytoplasm
Proteases
11. Addition polymerization is commonly initiated by ___ - atoms that have an unpaired electron.
cycles
Large
free radical
Macrophages
12. The glass transition temperature of a poymer at which a polymer transforms from a ____ state to a ___ state.
hypoxin - angiogenesis
glassy to rubbery
Lower
Hemophilia
13. Is directed cell migration in response to a concentration gradient of soluble molecules.
Chemotaxis
free radical
Enzyme cascade
labile cells
14. _____ establishes a quantitative relationship between measured output values from an instrument and known standards of what is being measured.
Calibration
Proteases
negative feedback
in cytoplasm
15. Keloid scars forms because disfuntion of
Collagenase
Amide
Intermolecular bonding - molecular weight
Macrophages
16. Which of polyermization (condensation/free radical) would you choose to obtain a polymer of high molecular weight?
Compression molding
Extrusion
Free Radical
negative feedback
17. Process of producing new blood vessels due to a lack on oxygen and thus inducing VEGF.
angiogenesis
Plastic
Heparin
photoactive polymers
18. Foreign body giants cells are produced by fusion of ___.
Heparin
negative feedback
Number of polymers - molecular weight of polymer
Macrophages
19. ____ describes the ability of a device to function appropriately in the presence of blood.
negative feedback
cross - linking
low
Hemocompatibility
20. Rather than randomly moving - moves in a directed cell migration manner for specific functions.
Negative Feedback
Positive Feedback
Heparin
chemotaxis
21. What type of materials are used for photolithography? (substrate is a silicon wafer - built up material is some _____ ____ )
Bioactive
Permanent - replicate
mast cells
photoactive polymers
22. The process of calibration establishes a quantitative relationship between ____ __ ___ _____ and the direct output of the intstrument (for example time/volume in GPC).
micromachining
heparin
standards of known properties
Large
23. Collagen ____ is responsible for the gradual gain in mechanical properties of wounded tissue between roughly 4 and 52 weeks post- injury.
Plasticizers
cross - linking
Protein Absorption
Thrombin
24. ____ binds to anti- thrombin III (thrombin inhibitor) and increases its potency 1000- fold.
Heparin
Collagenase
Hemophilia
Macrophages
25. Cells that proliferate slowly over time (aka liver)
heparin
Plasticizers
Stable cells
binding
26. Relative to free radical polymerization - condensation polymerization generally produces polymer of relatively ____ molecular weight.
mast cells
Phagocytosis
low
cross - linking
27. Damaged cells at the site of injury (mast cells) release ___ (glycosaminoglycan).
hypoxin - angiogenesis
Protein Absorption
chemotaxis
heparin
28. During granulation stage of proliferation - growth factors that produce this ____(answer)_____ that function in degrading fibrin and replacing it with collagen.
Stable cells
scars
Proteases
Number of polymers - molecular weight of polymer
29. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure
Endothelial cells
Stress
phagocytosis
standards of known properties
30. A ____ implant is designed to elicit specific - intended to host responses.
glassy to rubbery
Bioactive
low
Thrombin
31. Thrombin also activates protein C-- which deactivates earlier factors in the cascade is known as ___ ___.
Negative Feedback
labile cells
Extrusion
Plastic
32. Cells that don't proliferate (neurons)
Regeneration/Repair
Permanent cells
cross - linking
autologous
33. The fatigue limit is value of applied stress below which a material will not fail no matter the number of ____ applied.
glassy to rubbery
cycles
photoactive polymers
in cytoplasm
34. Type of fiber drawing that controls details of a polymer by etching on a microscopic level; thus - controlling mechanical properties as well
Polymers - cross linking of polymers
Calibration
Plasticizers
micromachining
35. The calculation of a polymer's molecular weight (weight average and number number average) is based upon values for ____ and ___.
Negative Feedback
Intermolecular bonding - molecular weight
Proteases
Number of polymers - molecular weight of polymer
36. Cells that proliferate rapidly (fibroblasts)
heparin
Have to be in a clean room free of dust and biocontamination - expensive
labile cells
neutrophils - macrophages
37. Higher Molecular weight degrades slower than ____ MW
Hemophilia
Lower
Amide
Negative Feedback
38. In order to produce a blood clot - thrombin cleaves/activates ____ and ____.
Permanent - replicate
photoactive polymers
binding
fibrinogen - factor XIII
39. The fibrous capsule surrounding a permanent implant is primarily composed of ___ cells and ____ (matrix).
Negative Feedback
Hemophilia
labile cells
Mast - Collagen
40. Drawback of micromaching
Have to be in a clean room free of dust and biocontamination - expensive
Collagenase/Remodelling
phagocytosis
Polydesperity index
41. Neutrophils remove bacteria/damaged cell debris from a wound site through the process of ___.
phagocytosis
chemotaxis
stress
hypoxin - angiogenesis
42. A molecular pathway in which the product of each reaction catalyzes the subsequent reaction.
heparin
Macrophages
angiogenesis
Enzyme cascade
43. Cardiac bypass surgery in which a vein from a patient's leg is transplanted to the patient's heart is an example of the us of ____ tissue.
chemotaxis
autologous
Calibration
Enzyme cascade
44. You're working on a square polymeric implant of 5cm length and 2mm thick. You've been asked to suggest a precise way to fabricate it - what would you suggest?
Negative Feedback
Stress
Compression molding
Thrombin
45. Thrombin activates several upstream factors.
Protein Absorption
Stable cells
Free Radical
Positive Feedback
46. Disfunction of _____ (cells) producing collagenase during the _____ phase of wound healing may form Keloid scars.
Positive Feedback
Thermoplastics
heparin
macrophages - proliferation
47. Mast cells release this
low
macrophages - proliferation
negative feedback
heparin
48. Activates tissue factors aka endothelial damage
Stress
Damage to cell membranes
scars
Polydesperity index
49. ____- are polymers that can be repeatedly softened by heating and hardened by cooling.
Macrophages
Stress
Thermoplastics
Hemocompatibility
50. The two types of white blood cells:
Lower
in cytoplasm
neutrophils - macrophages
Permanent - replicate
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