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Test your basic knowledge |
Bio Engineering
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Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. The fatigue limit is value of applied stress below which a material will not fail no matter the number of ____ applied.
Higher
Heparin
Allogeneic
cycles
2. Two things needed in the end product of the creation of a scab
Polymers - cross linking of polymers
heparin
in cytoplasm
autologous
3. Cells that don't proliferate (neurons)
Water - oxygen - metal
Permanent cells
phagocytosis
mast cells
4. Classify the following polymers into appropriate families based on their bond structure i.e. the polymer is an example of poly ____.
Amide
Water - oxygen - metal
micromachining
Chemotaxis
5. Cardiac bypass surgery in which a vein from a patient's leg is transplanted to the patient's heart is an example of the us of ____ tissue.
Heparin
autologous
Water
Calibration
6. ____- are polymers that can be repeatedly softened by heating and hardened by cooling.
Proteases
Thermoplastics
Proteases
Stress
7. Cells that proliferate slowly over time (aka liver)
Stable cells
micromachining
fibrinogen - factor XIII
Phagocytosis
8. Resulting from the build up of too much collagen at the surface of injury during the granulation tissue stage of proliferation
scars
low
Negative Feedback
Stable cells
9. During granulation stage of proliferation - growth factors that produce this ____(answer)_____ that function in degrading fibrin and replacing it with collagen.
Permanent - replicate
chemotaxis
Proteases
glassy to rubbery
10. ____ are enzymes responsible for protein degradation.
Thermoplastics
negative feedback
Calibration
Proteases
11. Drawback of micromaching
Hemophilia
Number of polymers - molecular weight of polymer
Proteases
Have to be in a clean room free of dust and biocontamination - expensive
12. ____ describes the ability of a device to function appropriately in the presence of blood.
stress
chemotaxis
Hemocompatibility
Compression molding
13. ____ is the process by which cells involved in inflammation internalize and destroy foreign material.
Compression molding
Phagocytosis
Heparin
Macrophages
14. Essentially all metallic biomaterials are ____ - comprised of two or more metals. One of these metals is selected for its ability to support _____ - the formation of a stable oxide layer that resists further corrosion.
alloys - passivation
heparin
Proteases
macrophages - proliferation
15. Keloid scars forms because disfuntion of
Amide
Collagenase
Mast - Collagen
cycles
16. Vascular endothelial growth factor is produced in response to ___ and stimulates ___.
Amide
hypoxin - angiogenesis
Thermoplastics
Mast - Collagen
17. ____ binds to anti- thrombin III (thrombin inhibitor) and increases its potency 1000- fold.
Heparin
Large
Intermolecular bonding - molecular weight
Allogeneic
18. Deformation that cannot be recovered once the load is removed from the material is ____ deformation.
Higher
Plastic
Polymers - cross linking of polymers
neutrophils - macrophages
19. Neutrophils remove bacteria/damaged cell debris from a wound site through the process of ___.
Positive Feedback
neutrophils - macrophages
phagocytosis
in cytoplasm
20. No healing of damage neurons is the result of ____ cells that are not able to ____.
Collagenase/Remodelling
Plastic
Free Radical
Permanent - replicate
21. The glass transition temperature of a poymer at which a polymer transforms from a ____ state to a ___ state.
micromachining
Thrombin
Free Radical
glassy to rubbery
22. Process of producing new blood vessels due to a lack on oxygen and thus inducing VEGF.
Regeneration/Repair
cycles
Permanent - replicate
angiogenesis
23. What types of wound healing results from injury with inflammation?
low
Collagenase/Remodelling
Regeneration/Repair
Thrombin
24. Process that makes long fibers (fiber drawing) by forcing a fluid through an oriface.
glassy to rubbery
Damage to cell membranes
Extrusion
heparin
25. Thrombin activates several upstream factors.
Positive Feedback
cross - linking
Water
Amide
26. The fibrous capsule surrounding a permanent implant is primarily composed of ___ cells and ____ (matrix).
Mast - Collagen
Polydesperity index
Proteases
alloys - passivation
27. ____ is a measurement that characterizes the breadth of the distribution of a polymer's molecular weight.
Polydesperity index
angiogenesis
Macrophages
Intermolecular bonding - molecular weight
28. Higher Molecular weight degrades slower than ____ MW
Lower
Collagenase
Free Radical
Protein Absorption
29. Type of fiber drawing that controls details of a polymer by etching on a microscopic level; thus - controlling mechanical properties as well
micromachining
Extrusion
Water - oxygen - metal
Proteases
30. A molecular pathway in which the product of each reaction catalyzes the subsequent reaction.
stress
Enzyme cascade
Collagenase/Remodelling
Damage to cell membranes
31. Thrombin also activates protein C-- which deactivates earlier factors in the cascade is known as ___ ___.
Negative Feedback
mast cells
Intermolecular bonding - molecular weight
photoactive polymers
32. Addition polymerization is commonly initiated by ___ - atoms that have an unpaired electron.
Compression molding
free radical
glassy to rubbery
Damage to cell membranes
33. ______ Molecular weight degrades slower than lower MW
Higher
low
free radical
Heparin
34. List two chemical characteristics of polymers:
neutrophils - macrophages
cross - linking
Intermolecular bonding - molecular weight
mast cells
35. This cleaves into fibrinogen which creates fibrin (a sticky enzyme that allows blood to clot)
micromachining
Thrombin
Polymers - cross linking of polymers
Lower
36. The trigger for activation of enzymes (anything but endothelial cells!)
Macrophages
binding
Intermolecular bonding - molecular weight
Large
37. What type of materials are used for photolithography? (substrate is a silicon wafer - built up material is some _____ ____ )
photoactive polymers
Higher
Extrusion
heparin
38. Relative to free radical polymerization - condensation polymerization generally produces polymer of relatively ____ molecular weight.
stress
Extrusion
Plasticizers
low
39. The formation of rust due to corrosion in the body is due to the reaction between these 3 things ____ - ____ - and ____ .
Water - oxygen - metal
Amide
macrophages - proliferation
Negative Feedback
40. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure
Have to be in a clean room free of dust and biocontamination - expensive
Stress
heparin
Enzyme cascade
41. Rather than randomly moving - moves in a directed cell migration manner for specific functions.
Thermoplastics
standards of known properties
chemotaxis
Enzyme cascade
42. Collagen ____ is responsible for the gradual gain in mechanical properties of wounded tissue between roughly 4 and 52 weeks post- injury.
scars
Extrusion
cross - linking
Mast - Collagen
43. The process of calibration establishes a quantitative relationship between ____ __ ___ _____ and the direct output of the intstrument (for example time/volume in GPC).
standards of known properties
alloys - passivation
Large
Collagenase
44. A ____ implant is designed to elicit specific - intended to host responses.
Macrophages
scars
Chemotaxis
Bioactive
45. Cell found in the lining of the blood vessels that release heparin and are a part of the negative feedback system.
cross - linking
mast cells
cycles
Stress
46. Cells that proliferate rapidly (fibroblasts)
cross - linking
Mast - Collagen
Polymers - cross linking of polymers
labile cells
47. You're working on a square polymeric implant of 5cm length and 2mm thick. You've been asked to suggest a precise way to fabricate it - what would you suggest?
Collagenase
Polymers - cross linking of polymers
Compression molding
Number of polymers - molecular weight of polymer
48. Is directed cell migration in response to a concentration gradient of soluble molecules.
Plastic
Hemocompatibility
Chemotaxis
mast cells
49. Condition in which patients can literally bleed to death.
free radical
Amide
hypoxin - angiogenesis
Hemophilia
50. Disfunction of _____ (cells) producing collagenase during the _____ phase of wound healing may form Keloid scars.
Endothelial cells
Protein Absorption
Bioactive
macrophages - proliferation
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