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Test your basic knowledge |
Bio Engineering
Start Test
Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Process of producing new blood vessels due to a lack on oxygen and thus inducing VEGF.
Hemophilia
Metals
angiogenesis
Number of polymers - molecular weight of polymer
2. The trigger for activation of enzymes (anything but endothelial cells!)
Damage to cell membranes
binding
in cytoplasm
Extrusion
3. ______ Molecular weight degrades slower than lower MW
low
Bioactive
Higher
Water - oxygen - metal
4. This type of feedback creates
negative feedback
Phagocytosis
Intermolecular bonding - molecular weight
Proteases
5. During granulation stage of proliferation - growth factors that produce this ____(answer)_____ that function in degrading fibrin and replacing it with collagen.
Metals
hypoxin - angiogenesis
Protein Absorption
Proteases
6. Enzyme that really gets the polmerization going!
Permanent cells
scars
Thrombin
Proteases
7. Cells that don't proliferate (neurons)
photoactive polymers
Proteases
Permanent cells
Calibration
8. Two things needed in the end product of the creation of a scab
Polymers - cross linking of polymers
binding
chemotaxis
Thrombin
9. This cleaves into fibrinogen which creates fibrin (a sticky enzyme that allows blood to clot)
photoactive polymers
Proteases
Extrusion
Thrombin
10. Damaged cells at the site of injury (mast cells) release ___ (glycosaminoglycan).
Thrombin
Hemophilia
heparin
Number of polymers - molecular weight of polymer
11. The fatigue limit is value of applied stress below which a material will not fail no matter the number of ____ applied.
Hemophilia
hypoxin - angiogenesis
cycles
Thrombin
12. Enzymes (proteins) are not activated only when they are in contact with this type of cells
Endothelial cells
scars
Polydesperity index
autologous
13. The formation of rust due to corrosion in the body is due to the reaction between these 3 things ____ - ____ - and ____ .
in cytoplasm
Positive Feedback
Lower
Water - oxygen - metal
14. Addition polymerization is commonly initiated by ___ - atoms that have an unpaired electron.
free radical
Have to be in a clean room free of dust and biocontamination - expensive
Collagenase/Remodelling
Polymers - cross linking of polymers
15. Collagen ____ is responsible for the gradual gain in mechanical properties of wounded tissue between roughly 4 and 52 weeks post- injury.
Bioactive
cross - linking
Plasticizers
Large
16. A molecular pathway in which the product of each reaction catalyzes the subsequent reaction.
Free Radical
Polymers - cross linking of polymers
Collagenase
Enzyme cascade
17. The two types of white blood cells:
Enzyme cascade
Compression molding
Heparin
neutrophils - macrophages
18. Resulting from the build up of too much collagen at the surface of injury during the granulation tissue stage of proliferation
binding
glassy to rubbery
scars
photoactive polymers
19. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure
glassy to rubbery
heparin
Stress
cycles
20. List two chemical characteristics of polymers:
standards of known properties
Thermoplastics
Intermolecular bonding - molecular weight
glassy to rubbery
21. Thrombin also activates protein C-- which deactivates earlier factors in the cascade is known as ___ ___.
Polydesperity index
Negative Feedback
neutrophils - macrophages
Thrombin
22. Are polymer additives used to lower glass transition temperature temperature.
Hemophilia
Allogeneic
Plasticizers
Calibration
23. Disfunction of _____ (cells) producing collagenase during the _____ phase of wound healing may form Keloid scars.
Calibration
macrophages - proliferation
Polydesperity index
Positive Feedback
24. Cells that proliferate slowly over time (aka liver)
Stable cells
alloys - passivation
labile cells
Proteases
25. Higher Molecular weight degrades slower than ____ MW
Lower
Number of polymers - molecular weight of polymer
Polymers - cross linking of polymers
low
26. You're working on a square polymeric implant of 5cm length and 2mm thick. You've been asked to suggest a precise way to fabricate it - what would you suggest?
Compression molding
fibrinogen - factor XIII
negative feedback
Phagocytosis
27. Deformation that cannot be recovered once the load is removed from the material is ____ deformation.
Positive Feedback
photoactive polymers
neutrophils - macrophages
Plastic
28. A ____ implant is designed to elicit specific - intended to host responses.
cycles
micromachining
Bioactive
heparin
29. ____ is the process by which cells involved in inflammation internalize and destroy foreign material.
Phagocytosis
Positive Feedback
Water - oxygen - metal
cross - linking
30. The calculation of a polymer's molecular weight (weight average and number number average) is based upon values for ____ and ___.
hypoxin - angiogenesis
Endothelial cells
Number of polymers - molecular weight of polymer
Heparin
31. Mast cells release this
Intermolecular bonding - molecular weight
heparin
binding
standards of known properties
32. ____ binds to anti- thrombin III (thrombin inhibitor) and increases its potency 1000- fold.
Heparin
in cytoplasm
hypoxin - angiogenesis
labile cells
33. Cells that proliferate rapidly (fibroblasts)
alloys - passivation
Number of polymers - molecular weight of polymer
Water - oxygen - metal
labile cells
34. Neutrophils remove bacteria/damaged cell debris from a wound site through the process of ___.
Amide
phagocytosis
Enzyme cascade
heparin
35. Classify the following polymers into appropriate families based on their bond structure i.e. the polymer is an example of poly ____.
Have to be in a clean room free of dust and biocontamination - expensive
low
Metals
Amide
36. Cell found in the lining of the blood vessels that release heparin and are a part of the negative feedback system.
Damage to cell membranes
chemotaxis
Extrusion
mast cells
37. ____- are polymers that can be repeatedly softened by heating and hardened by cooling.
Thermoplastics
Positive Feedback
labile cells
heparin
38. GPC separates molecules on the basis of size by their passage over a column packed with a porous matrix. ___ molecules pass through the column more quickly.
Large
Proteases
Thrombin
scars
39. Relative to free radical polymerization - condensation polymerization generally produces polymer of relatively ____ molecular weight.
angiogenesis
Large
Compression molding
low
40. Process that makes long fibers (fiber drawing) by forcing a fluid through an oriface.
phagocytosis
Thrombin
standards of known properties
Extrusion
41. Condition in which patients can literally bleed to death.
Polymers - cross linking of polymers
heparin
Hemophilia
chemotaxis
42. Rather than randomly moving - moves in a directed cell migration manner for specific functions.
chemotaxis
stress
Water
Number of polymers - molecular weight of polymer
43. Which of polyermization (condensation/free radical) would you choose to obtain a polymer of high molecular weight?
Free Radical
Thermoplastics
Regeneration/Repair
Chemotaxis
44. _____ establishes a quantitative relationship between measured output values from an instrument and known standards of what is being measured.
Thrombin
Calibration
Enzyme cascade
Plasticizers
45. No healing of damage neurons is the result of ____ cells that are not able to ____.
Extrusion
Enzyme cascade
Permanent - replicate
angiogenesis
46. Polyethylene oxide grafting to biomaterials was developed to prevent coagulation by interfering with/preventing ___ ___.
negative feedback
Protein Absorption
low
phagocytosis
47. Type of fiber drawing that controls details of a polymer by etching on a microscopic level; thus - controlling mechanical properties as well
Number of polymers - molecular weight of polymer
micromachining
Polymers - cross linking of polymers
Hemocompatibility
48. ____ is a measurement that characterizes the breadth of the distribution of a polymer's molecular weight.
angiogenesis
Number of polymers - molecular weight of polymer
Polydesperity index
Intermolecular bonding - molecular weight
49. ____ grafts are derived from the other humans.
Allogeneic
glassy to rubbery
Chemotaxis
mast cells
50. The fibrous capsule surrounding a permanent implant is primarily composed of ___ cells and ____ (matrix).
Collagenase
scars
Higher
Mast - Collagen