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Test your basic knowledge |
Bio Engineering
Start Test
Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Cells that proliferate rapidly (fibroblasts)
hypoxin - angiogenesis
heparin
Proteases
labile cells
2. Essentially all metallic biomaterials are ____ - comprised of two or more metals. One of these metals is selected for its ability to support _____ - the formation of a stable oxide layer that resists further corrosion.
Permanent - replicate
Endothelial cells
Proteases
alloys - passivation
3. Resulting from the build up of too much collagen at the surface of injury during the granulation tissue stage of proliferation
scars
hypoxin - angiogenesis
Water
Permanent - replicate
4. Disfunction of _____ (cells) producing collagenase during the _____ phase of wound healing may form Keloid scars.
micromachining
Calibration
Positive Feedback
macrophages - proliferation
5. Is directed cell migration in response to a concentration gradient of soluble molecules.
Higher
Permanent - replicate
Positive Feedback
Chemotaxis
6. Two things needed in the end product of the creation of a scab
Collagenase
Polymers - cross linking of polymers
Permanent cells
Thermoplastics
7. ____ binds to anti- thrombin III (thrombin inhibitor) and increases its potency 1000- fold.
Positive Feedback
Heparin
Collagenase/Remodelling
Bioactive
8. Where are the tissue factors found when they're inactivated
in cytoplasm
Calibration
micromachining
low
9. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure
Plastic
Stress
photoactive polymers
Negative Feedback
10. Which of polyermization (condensation/free radical) would you choose to obtain a polymer of high molecular weight?
Free Radical
Stress
Plastic
Number of polymers - molecular weight of polymer
11. Cell found in the lining of the blood vessels that release heparin and are a part of the negative feedback system.
Macrophages
Water
mast cells
Free Radical
12. Process that makes long fibers (fiber drawing) by forcing a fluid through an oriface.
Damage to cell membranes
Extrusion
Negative Feedback
Collagenase
13. You're working on a square polymeric implant of 5cm length and 2mm thick. You've been asked to suggest a precise way to fabricate it - what would you suggest?
heparin
Compression molding
Collagenase/Remodelling
autologous
14. GPC separates molecules on the basis of size by their passage over a column packed with a porous matrix. ___ molecules pass through the column more quickly.
Have to be in a clean room free of dust and biocontamination - expensive
Chemotaxis
Large
Thermoplastics
15. ____ are enzymes responsible for protein degradation.
cross - linking
Proteases
Number of polymers - molecular weight of polymer
Endothelial cells
16. The process of calibration establishes a quantitative relationship between ____ __ ___ _____ and the direct output of the intstrument (for example time/volume in GPC).
standards of known properties
Stress
Positive Feedback
labile cells
17. This cleaves into fibrinogen which creates fibrin (a sticky enzyme that allows blood to clot)
heparin
Thrombin
in cytoplasm
Enzyme cascade
18. Condition in which patients can literally bleed to death.
Hemophilia
hypoxin - angiogenesis
heparin
Hemocompatibility
19. Higher Molecular weight degrades slower than ____ MW
autologous
Macrophages
Lower
Compression molding
20. Cardiac bypass surgery in which a vein from a patient's leg is transplanted to the patient's heart is an example of the us of ____ tissue.
Collagenase
Chemotaxis
autologous
negative feedback
21. A condensation polymerization results with an ester bond between two reactants and this comes off as a result
labile cells
Have to be in a clean room free of dust and biocontamination - expensive
Water
Phagocytosis
22. The fibrous capsule surrounding a permanent implant is primarily composed of ___ cells and ____ (matrix).
binding
Plasticizers
Mast - Collagen
Metals
23. The formation of rust due to corrosion in the body is due to the reaction between these 3 things ____ - ____ - and ____ .
Water - oxygen - metal
Large
fibrinogen - factor XIII
Number of polymers - molecular weight of polymer
24. Neutrophils remove bacteria/damaged cell debris from a wound site through the process of ___.
Enzyme cascade
Protein Absorption
phagocytosis
Stress
25. Collagen ____ is responsible for the gradual gain in mechanical properties of wounded tissue between roughly 4 and 52 weeks post- injury.
Stress
Free Radical
Plasticizers
cross - linking
26. Cells that don't proliferate (neurons)
Polydesperity index
Permanent - replicate
Allogeneic
Permanent cells
27. Keloid scars form due to disfunction of ____.
Collagenase/Remodelling
Permanent cells
standards of known properties
alloys - passivation
28. ____ grafts are derived from the other humans.
standards of known properties
negative feedback
Allogeneic
macrophages - proliferation
29. During granulation stage of proliferation - growth factors that produce this ____(answer)_____ that function in degrading fibrin and replacing it with collagen.
binding
Collagenase
Proteases
Water
30. Keloid scars forms because disfuntion of
Stress
phagocytosis
Plastic
Collagenase
31. Are polymer additives used to lower glass transition temperature temperature.
Plasticizers
heparin
Heparin
Intermolecular bonding - molecular weight
32. _____ establishes a quantitative relationship between measured output values from an instrument and known standards of what is being measured.
low
standards of known properties
Calibration
Stress
33. Deformation that cannot be recovered once the load is removed from the material is ____ deformation.
in cytoplasm
labile cells
photoactive polymers
Plastic
34. Enzymes (proteins) are not activated only when they are in contact with this type of cells
Endothelial cells
Plasticizers
cycles
Number of polymers - molecular weight of polymer
35. ____ describes the ability of a device to function appropriately in the presence of blood.
Allogeneic
micromachining
Hemocompatibility
autologous
36. The two types of white blood cells:
neutrophils - macrophages
Regeneration/Repair
Positive Feedback
cross - linking
37. No healing of damage neurons is the result of ____ cells that are not able to ____.
photoactive polymers
Thrombin
Permanent - replicate
Stable cells
38. Relative to free radical polymerization - condensation polymerization generally produces polymer of relatively ____ molecular weight.
Macrophages
Water
low
Have to be in a clean room free of dust and biocontamination - expensive
39. Cells that proliferate slowly over time (aka liver)
Thermoplastics
Stable cells
Lower
binding
40. The trigger for activation of enzymes (anything but endothelial cells!)
Lower
binding
Stress
Chemotaxis
41. The fatigue limit is value of applied stress below which a material will not fail no matter the number of ____ applied.
cycles
Regeneration/Repair
glassy to rubbery
Thrombin
42. Mast cells release this
Macrophages
Water
Phagocytosis
heparin
43. The glass transition temperature of a poymer at which a polymer transforms from a ____ state to a ___ state.
heparin
Lower
Bioactive
glassy to rubbery
44. Vascular endothelial growth factor is produced in response to ___ and stimulates ___.
standards of known properties
hypoxin - angiogenesis
Polymers - cross linking of polymers
glassy to rubbery
45. Polyethylene oxide grafting to biomaterials was developed to prevent coagulation by interfering with/preventing ___ ___.
Thrombin
macrophages - proliferation
Protein Absorption
Allogeneic
46. Addition polymerization is commonly initiated by ___ - atoms that have an unpaired electron.
free radical
heparin
standards of known properties
negative feedback
47. Thrombin activates several upstream factors.
Hemophilia
Thrombin
low
Positive Feedback
48. ______ Molecular weight degrades slower than lower MW
Higher
cross - linking
macrophages - proliferation
Heparin
49. A ____ implant is designed to elicit specific - intended to host responses.
Protein Absorption
Regeneration/Repair
Permanent - replicate
Bioactive
50. Drawback of micromaching
Have to be in a clean room free of dust and biocontamination - expensive
Thrombin
Regeneration/Repair
Large