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Test your basic knowledge |
Bio Engineering
Start Test
Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Where are the tissue factors found when they're inactivated
Phagocytosis
Stress
in cytoplasm
stress
2. Rather than randomly moving - moves in a directed cell migration manner for specific functions.
Thrombin
Metals
Macrophages
chemotaxis
3. Disfunction of _____ (cells) producing collagenase during the _____ phase of wound healing may form Keloid scars.
Permanent - replicate
low
standards of known properties
macrophages - proliferation
4. Is directed cell migration in response to a concentration gradient of soluble molecules.
Thrombin
Chemotaxis
heparin
Hemocompatibility
5. ____ binds to anti- thrombin III (thrombin inhibitor) and increases its potency 1000- fold.
Heparin
in cytoplasm
standards of known properties
phagocytosis
6. Keloid scars form due to disfunction of ____.
Collagenase/Remodelling
Intermolecular bonding - molecular weight
macrophages - proliferation
Chemotaxis
7. Process of producing new blood vessels due to a lack on oxygen and thus inducing VEGF.
Negative Feedback
Water
Mast - Collagen
angiogenesis
8. List two chemical characteristics of polymers:
Phagocytosis
Intermolecular bonding - molecular weight
chemotaxis
Endothelial cells
9. In order to produce a blood clot - thrombin cleaves/activates ____ and ____.
Plastic
fibrinogen - factor XIII
Calibration
low
10. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure
Stress
Permanent cells
Permanent - replicate
fibrinogen - factor XIII
11. The fatigue limit is value of applied stress below which a material will not fail no matter the number of ____ applied.
cross - linking
cycles
Thrombin
Bioactive
12. A molecular pathway in which the product of each reaction catalyzes the subsequent reaction.
glassy to rubbery
Intermolecular bonding - molecular weight
Water
Enzyme cascade
13. The formation of rust due to corrosion in the body is due to the reaction between these 3 things ____ - ____ - and ____ .
Negative Feedback
glassy to rubbery
Water - oxygen - metal
low
14. Thrombin activates several upstream factors.
hypoxin - angiogenesis
Phagocytosis
Positive Feedback
Water - oxygen - metal
15. Collagen ____ is responsible for the gradual gain in mechanical properties of wounded tissue between roughly 4 and 52 weeks post- injury.
phagocytosis
cross - linking
Positive Feedback
angiogenesis
16. A condensation polymerization results with an ester bond between two reactants and this comes off as a result
Water
chemotaxis
Have to be in a clean room free of dust and biocontamination - expensive
negative feedback
17. A ____ implant is designed to elicit specific - intended to host responses.
Bioactive
Plastic
scars
Chemotaxis
18. Keloid scars forms because disfuntion of
labile cells
heparin
autologous
Collagenase
19. The glass transition temperature of a poymer at which a polymer transforms from a ____ state to a ___ state.
Regeneration/Repair
mast cells
glassy to rubbery
Compression molding
20. Drawback of micromaching
Have to be in a clean room free of dust and biocontamination - expensive
Water - oxygen - metal
macrophages - proliferation
Allogeneic
21. You're working on a square polymeric implant of 5cm length and 2mm thick. You've been asked to suggest a precise way to fabricate it - what would you suggest?
standards of known properties
Polymers - cross linking of polymers
Compression molding
Number of polymers - molecular weight of polymer
22. ______ Molecular weight degrades slower than lower MW
heparin
Higher
Bioactive
Thrombin
23. Cells that proliferate slowly over time (aka liver)
Large
Stable cells
micromachining
low
24. Thrombin also activates protein C-- which deactivates earlier factors in the cascade is known as ___ ___.
Thermoplastics
Negative Feedback
stress
cycles
25. Are polymer additives used to lower glass transition temperature temperature.
Heparin
Negative Feedback
Plasticizers
Positive Feedback
26. Classify the following polymers into appropriate families based on their bond structure i.e. the polymer is an example of poly ____.
Higher
Lower
Macrophages
Amide
27. Relative to free radical polymerization - condensation polymerization generally produces polymer of relatively ____ molecular weight.
heparin
low
Lower
Water - oxygen - metal
28. The two types of white blood cells:
neutrophils - macrophages
Negative Feedback
Lower
Endothelial cells
29. Addition polymerization is commonly initiated by ___ - atoms that have an unpaired electron.
Stress
photoactive polymers
chemotaxis
free radical
30. GPC separates molecules on the basis of size by their passage over a column packed with a porous matrix. ___ molecules pass through the column more quickly.
Large
Permanent - replicate
Thrombin
standards of known properties
31. Damaged cells at the site of injury (mast cells) release ___ (glycosaminoglycan).
heparin
Permanent cells
Collagenase
Calibration
32. During granulation stage of proliferation - growth factors that produce this ____(answer)_____ that function in degrading fibrin and replacing it with collagen.
Proteases
Allogeneic
Thermoplastics
Permanent - replicate
33. Which of polyermization (condensation/free radical) would you choose to obtain a polymer of high molecular weight?
Hemophilia
Free Radical
Hemocompatibility
Bioactive
34. This cleaves into fibrinogen which creates fibrin (a sticky enzyme that allows blood to clot)
Amide
Collagenase
Thrombin
Free Radical
35. ____ describes the ability of a device to function appropriately in the presence of blood.
Amide
low
Heparin
Hemocompatibility
36. What types of wound healing results from injury with inflammation?
autologous
Regeneration/Repair
Polydesperity index
Chemotaxis
37. The calculation of a polymer's molecular weight (weight average and number number average) is based upon values for ____ and ___.
Number of polymers - molecular weight of polymer
Stress
Proteases
free radical
38. Cell found in the lining of the blood vessels that release heparin and are a part of the negative feedback system.
Water - oxygen - metal
mast cells
Polymers - cross linking of polymers
chemotaxis
39. Enzymes (proteins) are not activated only when they are in contact with this type of cells
hypoxin - angiogenesis
Enzyme cascade
Endothelial cells
Hemocompatibility
40. No healing of damage neurons is the result of ____ cells that are not able to ____.
Enzyme cascade
Permanent - replicate
Plastic
fibrinogen - factor XIII
41. _____ establishes a quantitative relationship between measured output values from an instrument and known standards of what is being measured.
Water - oxygen - metal
Calibration
Amide
Hemocompatibility
42. Mast cells release this
Permanent cells
Number of polymers - molecular weight of polymer
heparin
free radical
43. Enzyme that really gets the polmerization going!
angiogenesis
labile cells
neutrophils - macrophages
Thrombin
44. What type of materials are used for photolithography? (substrate is a silicon wafer - built up material is some _____ ____ )
angiogenesis
photoactive polymers
Higher
Lower
45. Essentially all metallic biomaterials are ____ - comprised of two or more metals. One of these metals is selected for its ability to support _____ - the formation of a stable oxide layer that resists further corrosion.
hypoxin - angiogenesis
alloys - passivation
Water - oxygen - metal
Chemotaxis
46. ____ is the process by which cells involved in inflammation internalize and destroy foreign material.
photoactive polymers
Phagocytosis
Thrombin
binding
47. Process that makes long fibers (fiber drawing) by forcing a fluid through an oriface.
Thrombin
Extrusion
Higher
Bioactive
48. Cells that don't proliferate (neurons)
Macrophages
Permanent cells
Amide
standards of known properties
49. Polyethylene oxide grafting to biomaterials was developed to prevent coagulation by interfering with/preventing ___ ___.
heparin
Protein Absorption
Damage to cell membranes
Hemophilia
50. Deformation that cannot be recovered once the load is removed from the material is ____ deformation.
Thrombin
Plastic
free radical
Collagenase/Remodelling