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Test your basic knowledge |
Bio Engineering
Start Test
Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Addition polymerization is commonly initiated by ___ - atoms that have an unpaired electron.
free radical
Metals
Hemophilia
scars
2. No healing of damage neurons is the result of ____ cells that are not able to ____.
Permanent - replicate
Calibration
Protein Absorption
cycles
3. Keloid scars form due to disfunction of ____.
Proteases
Bioactive
Collagenase/Remodelling
neutrophils - macrophages
4. Higher Molecular weight degrades slower than ____ MW
Water
in cytoplasm
low
Lower
5. Two things needed in the end product of the creation of a scab
Damage to cell membranes
Have to be in a clean room free of dust and biocontamination - expensive
hypoxin - angiogenesis
Polymers - cross linking of polymers
6. ____ describes the ability of a device to function appropriately in the presence of blood.
labile cells
macrophages - proliferation
Hemocompatibility
mast cells
7. You're working on a square polymeric implant of 5cm length and 2mm thick. You've been asked to suggest a precise way to fabricate it - what would you suggest?
Calibration
Permanent - replicate
Free Radical
Compression molding
8. Cardiac bypass surgery in which a vein from a patient's leg is transplanted to the patient's heart is an example of the us of ____ tissue.
Proteases
autologous
Hemophilia
Extrusion
9. ____ binds to anti- thrombin III (thrombin inhibitor) and increases its potency 1000- fold.
alloys - passivation
labile cells
Heparin
Large
10. Type of fiber drawing that controls details of a polymer by etching on a microscopic level; thus - controlling mechanical properties as well
Macrophages
mast cells
micromachining
Large
11. ____ grafts are derived from the other humans.
hypoxin - angiogenesis
Allogeneic
Proteases
mast cells
12. Enzymes (proteins) are not activated only when they are in contact with this type of cells
Hemophilia
phagocytosis
Endothelial cells
Phagocytosis
13. Cells that don't proliferate (neurons)
Water
chemotaxis
Permanent cells
Calibration
14. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure
scars
macrophages - proliferation
Stress
Protein Absorption
15. Which of polyermization (condensation/free radical) would you choose to obtain a polymer of high molecular weight?
Calibration
angiogenesis
Endothelial cells
Free Radical
16. The two types of white blood cells:
neutrophils - macrophages
standards of known properties
photoactive polymers
chemotaxis
17. High conductivity - isotropic - crystalline
glassy to rubbery
Lower
Metals
binding
18. ______ Molecular weight degrades slower than lower MW
cycles
Water
Higher
chemotaxis
19. What types of wound healing results from injury with inflammation?
Heparin
heparin
Negative Feedback
Regeneration/Repair
20. Where are the tissue factors found when they're inactivated
low
stress
in cytoplasm
cross - linking
21. Classify the following polymers into appropriate families based on their bond structure i.e. the polymer is an example of poly ____.
free radical
Amide
Proteases
Thrombin
22. Process that makes long fibers (fiber drawing) by forcing a fluid through an oriface.
Extrusion
Positive Feedback
heparin
cross - linking
23. Foreign body giants cells are produced by fusion of ___.
phagocytosis
Have to be in a clean room free of dust and biocontamination - expensive
Proteases
Macrophages
24. Deformation that cannot be recovered once the load is removed from the material is ____ deformation.
Metals
fibrinogen - factor XIII
Allogeneic
Plastic
25. Damaged cells at the site of injury (mast cells) release ___ (glycosaminoglycan).
Thrombin
Number of polymers - molecular weight of polymer
Higher
heparin
26. During granulation stage of proliferation - growth factors that produce this ____(answer)_____ that function in degrading fibrin and replacing it with collagen.
alloys - passivation
Endothelial cells
Proteases
Bioactive
27. List two chemical characteristics of polymers:
Intermolecular bonding - molecular weight
chemotaxis
Calibration
Amide
28. Thrombin also activates protein C-- which deactivates earlier factors in the cascade is known as ___ ___.
Negative Feedback
Thrombin
glassy to rubbery
Damage to cell membranes
29. This type of feedback creates
heparin
negative feedback
Amide
Thermoplastics
30. A condensation polymerization results with an ester bond between two reactants and this comes off as a result
Large
Plasticizers
Permanent - replicate
Water
31. The calculation of a polymer's molecular weight (weight average and number number average) is based upon values for ____ and ___.
Stable cells
Water - oxygen - metal
Number of polymers - molecular weight of polymer
binding
32. ____ are enzymes responsible for protein degradation.
binding
fibrinogen - factor XIII
Proteases
Positive Feedback
33. Condition in which patients can literally bleed to death.
Polydesperity index
scars
Collagenase/Remodelling
Hemophilia
34. Drawback of micromaching
in cytoplasm
Have to be in a clean room free of dust and biocontamination - expensive
Negative Feedback
Collagenase/Remodelling
35. Relative to free radical polymerization - condensation polymerization generally produces polymer of relatively ____ molecular weight.
Intermolecular bonding - molecular weight
Permanent - replicate
Heparin
low
36. Cells that proliferate slowly over time (aka liver)
Mast - Collagen
Have to be in a clean room free of dust and biocontamination - expensive
Stable cells
standards of known properties
37. Essentially all metallic biomaterials are ____ - comprised of two or more metals. One of these metals is selected for its ability to support _____ - the formation of a stable oxide layer that resists further corrosion.
Lower
alloys - passivation
Water
Number of polymers - molecular weight of polymer
38. The fibrous capsule surrounding a permanent implant is primarily composed of ___ cells and ____ (matrix).
Proteases
Large
Mast - Collagen
Calibration
39. ____ is the process by which cells involved in inflammation internalize and destroy foreign material.
Damage to cell membranes
neutrophils - macrophages
Phagocytosis
Negative Feedback
40. Polyethylene oxide grafting to biomaterials was developed to prevent coagulation by interfering with/preventing ___ ___.
heparin
Metals
autologous
Protein Absorption
41. Cells that proliferate rapidly (fibroblasts)
Bioactive
Positive Feedback
Proteases
labile cells
42. Collagen ____ is responsible for the gradual gain in mechanical properties of wounded tissue between roughly 4 and 52 weeks post- injury.
Plasticizers
cross - linking
Lower
free radical
43. In order to produce a blood clot - thrombin cleaves/activates ____ and ____.
Bioactive
fibrinogen - factor XIII
Negative Feedback
Calibration
44. Cell found in the lining of the blood vessels that release heparin and are a part of the negative feedback system.
Damage to cell membranes
Permanent - replicate
mast cells
Extrusion
45. The process of calibration establishes a quantitative relationship between ____ __ ___ _____ and the direct output of the intstrument (for example time/volume in GPC).
Free Radical
standards of known properties
Water - oxygen - metal
Bioactive
46. What type of materials are used for photolithography? (substrate is a silicon wafer - built up material is some _____ ____ )
Thermoplastics
Permanent cells
photoactive polymers
Allogeneic
47. Activates tissue factors aka endothelial damage
chemotaxis
Enzyme cascade
Damage to cell membranes
Thrombin
48. Thrombin activates several upstream factors.
negative feedback
Water
Endothelial cells
Positive Feedback
49. The trigger for activation of enzymes (anything but endothelial cells!)
binding
Water - oxygen - metal
hypoxin - angiogenesis
standards of known properties
50. The glass transition temperature of a poymer at which a polymer transforms from a ____ state to a ___ state.
Regeneration/Repair
Thrombin
glassy to rubbery
phagocytosis