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Test your basic knowledge |
Bio Engineering
Start Test
Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. The process of calibration establishes a quantitative relationship between ____ __ ___ _____ and the direct output of the intstrument (for example time/volume in GPC).
Enzyme cascade
chemotaxis
standards of known properties
heparin
2. This type of feedback creates
cross - linking
neutrophils - macrophages
negative feedback
Polymers - cross linking of polymers
3. Relative to free radical polymerization - condensation polymerization generally produces polymer of relatively ____ molecular weight.
hypoxin - angiogenesis
Chemotaxis
heparin
low
4. Process that makes long fibers (fiber drawing) by forcing a fluid through an oriface.
Extrusion
Plasticizers
Enzyme cascade
Negative Feedback
5. High conductivity - isotropic - crystalline
Endothelial cells
labile cells
standards of known properties
Metals
6. Activates tissue factors aka endothelial damage
Thermoplastics
chemotaxis
Thrombin
Damage to cell membranes
7. ____ grafts are derived from the other humans.
Plastic
Polydesperity index
cycles
Allogeneic
8. Enzymes (proteins) are not activated only when they are in contact with this type of cells
Proteases
Compression molding
Proteases
Endothelial cells
9. Thrombin activates several upstream factors.
Proteases
Metals
Positive Feedback
Water
10. The fibrous capsule surrounding a permanent implant is primarily composed of ___ cells and ____ (matrix).
heparin
Water
Mast - Collagen
Heparin
11. Keloid scars form due to disfunction of ____.
Collagenase/Remodelling
Plastic
cycles
Macrophages
12. The formation of rust due to corrosion in the body is due to the reaction between these 3 things ____ - ____ - and ____ .
standards of known properties
Endothelial cells
Water - oxygen - metal
Thermoplastics
13. Cells that don't proliferate (neurons)
Negative Feedback
heparin
Higher
Permanent cells
14. Rather than randomly moving - moves in a directed cell migration manner for specific functions.
chemotaxis
heparin
Plastic
autologous
15. Two things needed in the end product of the creation of a scab
Permanent cells
Number of polymers - molecular weight of polymer
Polymers - cross linking of polymers
cross - linking
16. _____ establishes a quantitative relationship between measured output values from an instrument and known standards of what is being measured.
Calibration
cycles
Thrombin
Allogeneic
17. Process of producing new blood vessels due to a lack on oxygen and thus inducing VEGF.
Thrombin
angiogenesis
Endothelial cells
Polymers - cross linking of polymers
18. Classify the following polymers into appropriate families based on their bond structure i.e. the polymer is an example of poly ____.
Intermolecular bonding - molecular weight
Calibration
Amide
Endothelial cells
19. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure.
Positive Feedback
macrophages - proliferation
stress
angiogenesis
20. GPC separates molecules on the basis of size by their passage over a column packed with a porous matrix. ___ molecules pass through the column more quickly.
Plasticizers
Proteases
Regeneration/Repair
Large
21. Addition polymerization is commonly initiated by ___ - atoms that have an unpaired electron.
free radical
Endothelial cells
binding
Proteases
22. You're working on a square polymeric implant of 5cm length and 2mm thick. You've been asked to suggest a precise way to fabricate it - what would you suggest?
Protein Absorption
Bioactive
Compression molding
alloys - passivation
23. A condensation polymerization results with an ester bond between two reactants and this comes off as a result
Have to be in a clean room free of dust and biocontamination - expensive
Polydesperity index
Water
Lower
24. ____ describes the ability of a device to function appropriately in the presence of blood.
glassy to rubbery
labile cells
Hemocompatibility
Free Radical
25. Neutrophils remove bacteria/damaged cell debris from a wound site through the process of ___.
Polymers - cross linking of polymers
Stable cells
angiogenesis
phagocytosis
26. This cleaves into fibrinogen which creates fibrin (a sticky enzyme that allows blood to clot)
Hemophilia
Plasticizers
Proteases
Thrombin
27. The trigger for activation of enzymes (anything but endothelial cells!)
cycles
Collagenase/Remodelling
Extrusion
binding
28. Mast cells release this
Permanent cells
heparin
Free Radical
stress
29. Cells that proliferate slowly over time (aka liver)
Have to be in a clean room free of dust and biocontamination - expensive
Macrophages
Collagenase/Remodelling
Stable cells
30. Where are the tissue factors found when they're inactivated
in cytoplasm
Stress
chemotaxis
heparin
31. Keloid scars forms because disfuntion of
Free Radical
Collagenase
Lower
labile cells
32. Higher Molecular weight degrades slower than ____ MW
Higher
autologous
Lower
Water
33. Collagen ____ is responsible for the gradual gain in mechanical properties of wounded tissue between roughly 4 and 52 weeks post- injury.
alloys - passivation
Stable cells
Permanent - replicate
cross - linking
34. During granulation stage of proliferation - growth factors that produce this ____(answer)_____ that function in degrading fibrin and replacing it with collagen.
phagocytosis
Proteases
Lower
fibrinogen - factor XIII
35. ____- are polymers that can be repeatedly softened by heating and hardened by cooling.
heparin
in cytoplasm
Proteases
Thermoplastics
36. A molecular pathway in which the product of each reaction catalyzes the subsequent reaction.
Collagenase
in cytoplasm
Enzyme cascade
neutrophils - macrophages
37. Type of fiber drawing that controls details of a polymer by etching on a microscopic level; thus - controlling mechanical properties as well
Hemophilia
micromachining
Water - oxygen - metal
low
38. Essentially all metallic biomaterials are ____ - comprised of two or more metals. One of these metals is selected for its ability to support _____ - the formation of a stable oxide layer that resists further corrosion.
Endothelial cells
alloys - passivation
Protein Absorption
Amide
39. Foreign body giants cells are produced by fusion of ___.
Endothelial cells
Have to be in a clean room free of dust and biocontamination - expensive
Phagocytosis
Macrophages
40. ____ binds to anti- thrombin III (thrombin inhibitor) and increases its potency 1000- fold.
chemotaxis
Heparin
hypoxin - angiogenesis
alloys - passivation
41. Disfunction of _____ (cells) producing collagenase during the _____ phase of wound healing may form Keloid scars.
micromachining
heparin
Higher
macrophages - proliferation
42. Resulting from the build up of too much collagen at the surface of injury during the granulation tissue stage of proliferation
Collagenase/Remodelling
scars
Polydesperity index
negative feedback
43. No healing of damage neurons is the result of ____ cells that are not able to ____.
Bioactive
Metals
Thrombin
Permanent - replicate
44. What type of materials are used for photolithography? (substrate is a silicon wafer - built up material is some _____ ____ )
photoactive polymers
chemotaxis
in cytoplasm
Calibration
45. Cells that proliferate rapidly (fibroblasts)
labile cells
micromachining
in cytoplasm
binding
46. Cardiac bypass surgery in which a vein from a patient's leg is transplanted to the patient's heart is an example of the us of ____ tissue.
autologous
Polydesperity index
free radical
hypoxin - angiogenesis
47. Drawback of micromaching
Have to be in a clean room free of dust and biocontamination - expensive
Stable cells
standards of known properties
Lower
48. A ____ implant is designed to elicit specific - intended to host responses.
Positive Feedback
Bioactive
Collagenase
Hemophilia
49. Damaged cells at the site of injury (mast cells) release ___ (glycosaminoglycan).
low
phagocytosis
heparin
mast cells
50. List two chemical characteristics of polymers:
labile cells
Polymers - cross linking of polymers
Intermolecular bonding - molecular weight
fibrinogen - factor XIII