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Test your basic knowledge |
Bio Engineering
Start Test
Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 30 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. The fatigue limit is value of applied stress below which a material will not fail no matter the number of ____ applied.
cycles
Have to be in a clean room free of dust and biocontamination - expensive
Free Radical
negative feedback
2. Essentially all metallic biomaterials are ____ - comprised of two or more metals. One of these metals is selected for its ability to support _____ - the formation of a stable oxide layer that resists further corrosion.
alloys - passivation
scars
Free Radical
Stable cells
3. The formation of rust due to corrosion in the body is due to the reaction between these 3 things ____ - ____ - and ____ .
Water - oxygen - metal
Permanent cells
Metals
Negative Feedback
4. Enzyme that really gets the polmerization going!
free radical
autologous
Thrombin
Hemocompatibility
5. Keloid scars form due to disfunction of ____.
Number of polymers - molecular weight of polymer
Metals
Collagenase/Remodelling
Large
6. ____ grafts are derived from the other humans.
Allogeneic
Endothelial cells
Thermoplastics
Negative Feedback
7. Thrombin also activates protein C-- which deactivates earlier factors in the cascade is known as ___ ___.
Stable cells
angiogenesis
Negative Feedback
Permanent - replicate
8. Foreign body giants cells are produced by fusion of ___.
Macrophages
Thermoplastics
alloys - passivation
Phagocytosis
9. A condensation polymerization results with an ester bond between two reactants and this comes off as a result
labile cells
Water
Free Radical
Heparin
10. Keloid scars forms because disfuntion of
Collagenase
Thrombin
Metals
Have to be in a clean room free of dust and biocontamination - expensive
11. Polyethylene oxide grafting to biomaterials was developed to prevent coagulation by interfering with/preventing ___ ___.
Protein Absorption
Collagenase/Remodelling
Damage to cell membranes
Allogeneic
12. Deformation that cannot be recovered once the load is removed from the material is ____ deformation.
Plasticizers
glassy to rubbery
Plastic
Proteases
13. Vascular endothelial growth factor is produced in response to ___ and stimulates ___.
binding
heparin
hypoxin - angiogenesis
standards of known properties
14. Are polymer additives used to lower glass transition temperature temperature.
cross - linking
Lower
Heparin
Plasticizers
15. Neutrophils remove bacteria/damaged cell debris from a wound site through the process of ___.
Water
phagocytosis
Proteases
Stable cells
16. ____ binds to anti- thrombin III (thrombin inhibitor) and increases its potency 1000- fold.
Water
Macrophages
Heparin
Proteases
17. Resulting from the build up of too much collagen at the surface of injury during the granulation tissue stage of proliferation
cycles
scars
glassy to rubbery
Hemocompatibility
18. A molecular pathway in which the product of each reaction catalyzes the subsequent reaction.
Calibration
Proteases
Free Radical
Enzyme cascade
19. Process that makes long fibers (fiber drawing) by forcing a fluid through an oriface.
Thermoplastics
cross - linking
Proteases
Extrusion
20. Type of fiber drawing that controls details of a polymer by etching on a microscopic level; thus - controlling mechanical properties as well
cycles
micromachining
free radical
Thrombin
21. The process of calibration establishes a quantitative relationship between ____ __ ___ _____ and the direct output of the intstrument (for example time/volume in GPC).
Heparin
Intermolecular bonding - molecular weight
standards of known properties
Stable cells
22. GPC separates molecules on the basis of size by their passage over a column packed with a porous matrix. ___ molecules pass through the column more quickly.
Large
negative feedback
Plastic
Free Radical
23. ____ is a measurement that characterizes the breadth of the distribution of a polymer's molecular weight.
Polydesperity index
Water - oxygen - metal
Positive Feedback
Damage to cell membranes
24. The fibrous capsule surrounding a permanent implant is primarily composed of ___ cells and ____ (matrix).
chemotaxis
standards of known properties
photoactive polymers
Mast - Collagen
25. Which of polyermization (condensation/free radical) would you choose to obtain a polymer of high molecular weight?
Heparin
binding
Free Radical
Macrophages
26. In order to produce a blood clot - thrombin cleaves/activates ____ and ____.
macrophages - proliferation
fibrinogen - factor XIII
Number of polymers - molecular weight of polymer
hypoxin - angiogenesis
27. What types of wound healing results from injury with inflammation?
Damage to cell membranes
cross - linking
Proteases
Regeneration/Repair
28. Cells that proliferate rapidly (fibroblasts)
Thermoplastics
Proteases
labile cells
Hemophilia
29. What type of materials are used for photolithography? (substrate is a silicon wafer - built up material is some _____ ____ )
photoactive polymers
Extrusion
alloys - passivation
Macrophages
30. High conductivity - isotropic - crystalline
Endothelial cells
heparin
Metals
Permanent cells
31. Collagen ____ is responsible for the gradual gain in mechanical properties of wounded tissue between roughly 4 and 52 weeks post- injury.
cross - linking
Higher
Phagocytosis
scars
32. Cells that don't proliferate (neurons)
Macrophages
Permanent cells
Polymers - cross linking of polymers
chemotaxis
33. The glass transition temperature of a poymer at which a polymer transforms from a ____ state to a ___ state.
scars
Stress
cycles
glassy to rubbery
34. ____ describes the ability of a device to function appropriately in the presence of blood.
Hemocompatibility
Mast - Collagen
standards of known properties
Phagocytosis
35. List two chemical characteristics of polymers:
Collagenase
Heparin
low
Intermolecular bonding - molecular weight
36. Cells that proliferate slowly over time (aka liver)
Collagenase/Remodelling
Positive Feedback
Water
Stable cells
37. This type of feedback creates
Damage to cell membranes
alloys - passivation
negative feedback
photoactive polymers
38. Two things needed in the end product of the creation of a scab
heparin
Extrusion
Polymers - cross linking of polymers
Allogeneic
39. Where are the tissue factors found when they're inactivated
in cytoplasm
free radical
standards of known properties
angiogenesis
40. ______ Molecular weight degrades slower than lower MW
Higher
Permanent cells
scars
Proteases
41. Cell found in the lining of the blood vessels that release heparin and are a part of the negative feedback system.
Thrombin
chemotaxis
angiogenesis
mast cells
42. Relative to free radical polymerization - condensation polymerization generally produces polymer of relatively ____ molecular weight.
low
Free Radical
chemotaxis
Extrusion
43. A ____ implant is designed to elicit specific - intended to host responses.
Damage to cell membranes
Bioactive
Hemophilia
alloys - passivation
44. Is directed cell migration in response to a concentration gradient of soluble molecules.
Chemotaxis
heparin
photoactive polymers
Free Radical
45. You're working on a square polymeric implant of 5cm length and 2mm thick. You've been asked to suggest a precise way to fabricate it - what would you suggest?
Compression molding
Higher
Water - oxygen - metal
Negative Feedback
46. Condition in which patients can literally bleed to death.
autologous
Amide
heparin
Hemophilia
47. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure
heparin
Stress
Polydesperity index
Polymers - cross linking of polymers
48. Addition polymerization is commonly initiated by ___ - atoms that have an unpaired electron.
Thrombin
free radical
photoactive polymers
negative feedback
49. No healing of damage neurons is the result of ____ cells that are not able to ____.
Regeneration/Repair
Permanent - replicate
Water - oxygen - metal
Calibration
50. Disfunction of _____ (cells) producing collagenase during the _____ phase of wound healing may form Keloid scars.
Metals
Damage to cell membranes
macrophages - proliferation
Regeneration/Repair