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Test your basic knowledge |
Bio Engineering
Start Test
Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. A molecular pathway in which the product of each reaction catalyzes the subsequent reaction.
Large
Enzyme cascade
Have to be in a clean room free of dust and biocontamination - expensive
standards of known properties
2. Cell found in the lining of the blood vessels that release heparin and are a part of the negative feedback system.
Allogeneic
Calibration
Lower
mast cells
3. Is directed cell migration in response to a concentration gradient of soluble molecules.
phagocytosis
Chemotaxis
Mast - Collagen
micromachining
4. Are polymer additives used to lower glass transition temperature temperature.
Plasticizers
Extrusion
Proteases
Protein Absorption
5. Disfunction of _____ (cells) producing collagenase during the _____ phase of wound healing may form Keloid scars.
Polydesperity index
macrophages - proliferation
Stable cells
standards of known properties
6. The fibrous capsule surrounding a permanent implant is primarily composed of ___ cells and ____ (matrix).
Mast - Collagen
Water - oxygen - metal
scars
autologous
7. Process that makes long fibers (fiber drawing) by forcing a fluid through an oriface.
Protein Absorption
Extrusion
Heparin
heparin
8. Enzymes (proteins) are not activated only when they are in contact with this type of cells
Endothelial cells
Number of polymers - molecular weight of polymer
Higher
macrophages - proliferation
9. A ____ implant is designed to elicit specific - intended to host responses.
Bioactive
Large
stress
fibrinogen - factor XIII
10. GPC separates molecules on the basis of size by their passage over a column packed with a porous matrix. ___ molecules pass through the column more quickly.
Large
Proteases
photoactive polymers
hypoxin - angiogenesis
11. Keloid scars form due to disfunction of ____.
Collagenase/Remodelling
photoactive polymers
macrophages - proliferation
low
12. Collagen ____ is responsible for the gradual gain in mechanical properties of wounded tissue between roughly 4 and 52 weeks post- injury.
cross - linking
Compression molding
macrophages - proliferation
Metals
13. In order to produce a blood clot - thrombin cleaves/activates ____ and ____.
Water - oxygen - metal
free radical
standards of known properties
fibrinogen - factor XIII
14. The calculation of a polymer's molecular weight (weight average and number number average) is based upon values for ____ and ___.
Damage to cell membranes
neutrophils - macrophages
Calibration
Number of polymers - molecular weight of polymer
15. Polyethylene oxide grafting to biomaterials was developed to prevent coagulation by interfering with/preventing ___ ___.
macrophages - proliferation
Thermoplastics
Plasticizers
Protein Absorption
16. Which of polyermization (condensation/free radical) would you choose to obtain a polymer of high molecular weight?
Positive Feedback
cycles
Free Radical
Thermoplastics
17. Condition in which patients can literally bleed to death.
Hemophilia
Collagenase/Remodelling
Negative Feedback
Free Radical
18. Cells that proliferate slowly over time (aka liver)
autologous
Stable cells
Hemophilia
Thrombin
19. ____- are polymers that can be repeatedly softened by heating and hardened by cooling.
free radical
Thermoplastics
Collagenase/Remodelling
Free Radical
20. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure.
Damage to cell membranes
labile cells
stress
chemotaxis
21. ____ describes the ability of a device to function appropriately in the presence of blood.
Water
Permanent - replicate
Hemocompatibility
angiogenesis
22. Addition polymerization is commonly initiated by ___ - atoms that have an unpaired electron.
mast cells
labile cells
Higher
free radical
23. A condensation polymerization results with an ester bond between two reactants and this comes off as a result
Thrombin
Allogeneic
glassy to rubbery
Water
24. Essentially all metallic biomaterials are ____ - comprised of two or more metals. One of these metals is selected for its ability to support _____ - the formation of a stable oxide layer that resists further corrosion.
alloys - passivation
Polydesperity index
photoactive polymers
Stable cells
25. Type of fiber drawing that controls details of a polymer by etching on a microscopic level; thus - controlling mechanical properties as well
micromachining
in cytoplasm
fibrinogen - factor XIII
Plastic
26. ____ binds to anti- thrombin III (thrombin inhibitor) and increases its potency 1000- fold.
Heparin
Positive Feedback
Hemophilia
Regeneration/Repair
27. This cleaves into fibrinogen which creates fibrin (a sticky enzyme that allows blood to clot)
Thrombin
Plasticizers
stress
macrophages - proliferation
28. ____ are enzymes responsible for protein degradation.
Large
binding
Proteases
Polydesperity index
29. Activates tissue factors aka endothelial damage
Damage to cell membranes
Polymers - cross linking of polymers
Enzyme cascade
Collagenase
30. This type of feedback creates
low
Positive Feedback
negative feedback
Regeneration/Repair
31. ____ grafts are derived from the other humans.
macrophages - proliferation
Have to be in a clean room free of dust and biocontamination - expensive
Plasticizers
Allogeneic
32. Resulting from the build up of too much collagen at the surface of injury during the granulation tissue stage of proliferation
Extrusion
Thermoplastics
chemotaxis
scars
33. Thrombin also activates protein C-- which deactivates earlier factors in the cascade is known as ___ ___.
chemotaxis
Thrombin
fibrinogen - factor XIII
Negative Feedback
34. The process of calibration establishes a quantitative relationship between ____ __ ___ _____ and the direct output of the intstrument (for example time/volume in GPC).
Enzyme cascade
Thrombin
Regeneration/Repair
standards of known properties
35. High conductivity - isotropic - crystalline
Metals
heparin
Large
Chemotaxis
36. Damaged cells at the site of injury (mast cells) release ___ (glycosaminoglycan).
free radical
low
heparin
Collagenase
37. ____ is a measurement that characterizes the breadth of the distribution of a polymer's molecular weight.
Bioactive
Endothelial cells
Protein Absorption
Polydesperity index
38. During granulation stage of proliferation - growth factors that produce this ____(answer)_____ that function in degrading fibrin and replacing it with collagen.
Calibration
Positive Feedback
Proteases
negative feedback
39. Thrombin activates several upstream factors.
Amide
Permanent - replicate
Heparin
Positive Feedback
40. No healing of damage neurons is the result of ____ cells that are not able to ____.
Macrophages
Permanent - replicate
Compression molding
Regeneration/Repair
41. You're working on a square polymeric implant of 5cm length and 2mm thick. You've been asked to suggest a precise way to fabricate it - what would you suggest?
Compression molding
Amide
Regeneration/Repair
standards of known properties
42. ______ Molecular weight degrades slower than lower MW
Damage to cell membranes
Lower
cycles
Higher
43. List two chemical characteristics of polymers:
phagocytosis
autologous
Intermolecular bonding - molecular weight
Protein Absorption
44. Classify the following polymers into appropriate families based on their bond structure i.e. the polymer is an example of poly ____.
photoactive polymers
Amide
autologous
Damage to cell membranes
45. Relative to free radical polymerization - condensation polymerization generally produces polymer of relatively ____ molecular weight.
low
Macrophages
cycles
Chemotaxis
46. The formation of rust due to corrosion in the body is due to the reaction between these 3 things ____ - ____ - and ____ .
Mast - Collagen
Water - oxygen - metal
micromachining
mast cells
47. The fatigue limit is value of applied stress below which a material will not fail no matter the number of ____ applied.
Large
cycles
Mast - Collagen
Compression molding
48. The trigger for activation of enzymes (anything but endothelial cells!)
phagocytosis
binding
negative feedback
Positive Feedback
49. Drawback of micromaching
alloys - passivation
Water - oxygen - metal
Amide
Have to be in a clean room free of dust and biocontamination - expensive
50. Cardiac bypass surgery in which a vein from a patient's leg is transplanted to the patient's heart is an example of the us of ____ tissue.
autologous
Macrophages
labile cells
Large