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Test your basic knowledge |
Bio Engineering
Start Test
Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. The trigger for activation of enzymes (anything but endothelial cells!)
binding
Proteases
autologous
Water - oxygen - metal
2. Is directed cell migration in response to a concentration gradient of soluble molecules.
neutrophils - macrophages
Bioactive
Collagenase
Chemotaxis
3. High conductivity - isotropic - crystalline
Polymers - cross linking of polymers
Higher
alloys - passivation
Metals
4. Process that makes long fibers (fiber drawing) by forcing a fluid through an oriface.
phagocytosis
free radical
stress
Extrusion
5. Addition polymerization is commonly initiated by ___ - atoms that have an unpaired electron.
Mast - Collagen
cycles
free radical
Thrombin
6. This cleaves into fibrinogen which creates fibrin (a sticky enzyme that allows blood to clot)
Thrombin
Polymers - cross linking of polymers
micromachining
standards of known properties
7. ____ is a measurement that characterizes the breadth of the distribution of a polymer's molecular weight.
Polydesperity index
standards of known properties
Permanent - replicate
Hemophilia
8. During granulation stage of proliferation - growth factors that produce this ____(answer)_____ that function in degrading fibrin and replacing it with collagen.
Polydesperity index
Proteases
Chemotaxis
Thermoplastics
9. Cells that proliferate slowly over time (aka liver)
Positive Feedback
Endothelial cells
Stable cells
Permanent cells
10. You're working on a square polymeric implant of 5cm length and 2mm thick. You've been asked to suggest a precise way to fabricate it - what would you suggest?
autologous
Permanent - replicate
Compression molding
Thrombin
11. The fatigue limit is value of applied stress below which a material will not fail no matter the number of ____ applied.
cycles
Heparin
low
Endothelial cells
12. Essentially all metallic biomaterials are ____ - comprised of two or more metals. One of these metals is selected for its ability to support _____ - the formation of a stable oxide layer that resists further corrosion.
photoactive polymers
Damage to cell membranes
alloys - passivation
in cytoplasm
13. List two chemical characteristics of polymers:
Phagocytosis
Intermolecular bonding - molecular weight
Compression molding
phagocytosis
14. _____ establishes a quantitative relationship between measured output values from an instrument and known standards of what is being measured.
Macrophages
alloys - passivation
glassy to rubbery
Calibration
15. The formation of rust due to corrosion in the body is due to the reaction between these 3 things ____ - ____ - and ____ .
Extrusion
fibrinogen - factor XIII
Water - oxygen - metal
Water
16. The calculation of a polymer's molecular weight (weight average and number number average) is based upon values for ____ and ___.
in cytoplasm
alloys - passivation
Number of polymers - molecular weight of polymer
Enzyme cascade
17. Two things needed in the end product of the creation of a scab
Hemocompatibility
Polymers - cross linking of polymers
heparin
Free Radical
18. Thrombin activates several upstream factors.
Positive Feedback
Large
Intermolecular bonding - molecular weight
Bioactive
19. The fibrous capsule surrounding a permanent implant is primarily composed of ___ cells and ____ (matrix).
Mast - Collagen
Collagenase
fibrinogen - factor XIII
Stable cells
20. Polyethylene oxide grafting to biomaterials was developed to prevent coagulation by interfering with/preventing ___ ___.
Metals
chemotaxis
autologous
Protein Absorption
21. Which of polyermization (condensation/free radical) would you choose to obtain a polymer of high molecular weight?
Thermoplastics
Chemotaxis
autologous
Free Radical
22. No healing of damage neurons is the result of ____ cells that are not able to ____.
Amide
Higher
Permanent - replicate
cycles
23. The process of calibration establishes a quantitative relationship between ____ __ ___ _____ and the direct output of the intstrument (for example time/volume in GPC).
Negative Feedback
Plastic
standards of known properties
Have to be in a clean room free of dust and biocontamination - expensive
24. Thrombin also activates protein C-- which deactivates earlier factors in the cascade is known as ___ ___.
cycles
heparin
Negative Feedback
Thrombin
25. Drawback of micromaching
mast cells
Polydesperity index
Have to be in a clean room free of dust and biocontamination - expensive
Macrophages
26. Where are the tissue factors found when they're inactivated
Number of polymers - molecular weight of polymer
Regeneration/Repair
in cytoplasm
Phagocytosis
27. Keloid scars form due to disfunction of ____.
Number of polymers - molecular weight of polymer
negative feedback
Collagenase/Remodelling
micromachining
28. Foreign body giants cells are produced by fusion of ___.
macrophages - proliferation
Thrombin
labile cells
Macrophages
29. Deformation that cannot be recovered once the load is removed from the material is ____ deformation.
Thrombin
in cytoplasm
Proteases
Plastic
30. Collagen ____ is responsible for the gradual gain in mechanical properties of wounded tissue between roughly 4 and 52 weeks post- injury.
cross - linking
glassy to rubbery
Stable cells
Bioactive
31. Neutrophils remove bacteria/damaged cell debris from a wound site through the process of ___.
stress
Water
phagocytosis
macrophages - proliferation
32. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure.
Metals
chemotaxis
stress
Water
33. Are polymer additives used to lower glass transition temperature temperature.
Permanent cells
in cytoplasm
Stress
Plasticizers
34. GPC separates molecules on the basis of size by their passage over a column packed with a porous matrix. ___ molecules pass through the column more quickly.
micromachining
Calibration
Thermoplastics
Large
35. A ____ implant is designed to elicit specific - intended to host responses.
Bioactive
Enzyme cascade
Thermoplastics
Polymers - cross linking of polymers
36. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure
Large
autologous
Macrophages
Stress
37. Relative to free radical polymerization - condensation polymerization generally produces polymer of relatively ____ molecular weight.
Protein Absorption
Mast - Collagen
Collagenase
low
38. Condition in which patients can literally bleed to death.
angiogenesis
cycles
Number of polymers - molecular weight of polymer
Hemophilia
39. Classify the following polymers into appropriate families based on their bond structure i.e. the polymer is an example of poly ____.
heparin
Amide
glassy to rubbery
cross - linking
40. ____ are enzymes responsible for protein degradation.
Proteases
Have to be in a clean room free of dust and biocontamination - expensive
Damage to cell membranes
Negative Feedback
41. This type of feedback creates
binding
negative feedback
Bioactive
Protein Absorption
42. Higher Molecular weight degrades slower than ____ MW
Enzyme cascade
Lower
Thrombin
Collagenase
43. Disfunction of _____ (cells) producing collagenase during the _____ phase of wound healing may form Keloid scars.
macrophages - proliferation
hypoxin - angiogenesis
Enzyme cascade
Hemocompatibility
44. Cardiac bypass surgery in which a vein from a patient's leg is transplanted to the patient's heart is an example of the us of ____ tissue.
Permanent - replicate
cross - linking
heparin
autologous
45. A molecular pathway in which the product of each reaction catalyzes the subsequent reaction.
Calibration
Water
in cytoplasm
Enzyme cascade
46. Mast cells release this
hypoxin - angiogenesis
chemotaxis
heparin
photoactive polymers
47. What types of wound healing results from injury with inflammation?
Enzyme cascade
photoactive polymers
Regeneration/Repair
mast cells
48. Cells that proliferate rapidly (fibroblasts)
labile cells
Stress
Proteases
Permanent cells
49. Enzymes (proteins) are not activated only when they are in contact with this type of cells
Stress
Negative Feedback
Endothelial cells
Collagenase/Remodelling
50. ____ grafts are derived from the other humans.
Allogeneic
Positive Feedback
Calibration
Proteases