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Test your basic knowledge |
Bio Engineering
Start Test
Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. The process of calibration establishes a quantitative relationship between ____ __ ___ _____ and the direct output of the intstrument (for example time/volume in GPC).
Compression molding
cross - linking
in cytoplasm
standards of known properties
2. Condition in which patients can literally bleed to death.
stress
macrophages - proliferation
Have to be in a clean room free of dust and biocontamination - expensive
Hemophilia
3. Drawback of micromaching
Hemocompatibility
Bioactive
Have to be in a clean room free of dust and biocontamination - expensive
Collagenase
4. ____ binds to anti- thrombin III (thrombin inhibitor) and increases its potency 1000- fold.
Water - oxygen - metal
photoactive polymers
Heparin
binding
5. During granulation stage of proliferation - growth factors that produce this ____(answer)_____ that function in degrading fibrin and replacing it with collagen.
Endothelial cells
angiogenesis
Proteases
Protein Absorption
6. You're working on a square polymeric implant of 5cm length and 2mm thick. You've been asked to suggest a precise way to fabricate it - what would you suggest?
Collagenase/Remodelling
Compression molding
Damage to cell membranes
low
7. Polyethylene oxide grafting to biomaterials was developed to prevent coagulation by interfering with/preventing ___ ___.
Allogeneic
Protein Absorption
autologous
hypoxin - angiogenesis
8. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure
Proteases
Stress
heparin
Permanent - replicate
9. This type of feedback creates
Phagocytosis
negative feedback
Calibration
Compression molding
10. Type of fiber drawing that controls details of a polymer by etching on a microscopic level; thus - controlling mechanical properties as well
Enzyme cascade
micromachining
heparin
macrophages - proliferation
11. Disfunction of _____ (cells) producing collagenase during the _____ phase of wound healing may form Keloid scars.
Proteases
macrophages - proliferation
Polymers - cross linking of polymers
Protein Absorption
12. The glass transition temperature of a poymer at which a polymer transforms from a ____ state to a ___ state.
Enzyme cascade
Stress
binding
glassy to rubbery
13. No healing of damage neurons is the result of ____ cells that are not able to ____.
autologous
Permanent - replicate
Thrombin
low
14. Thrombin also activates protein C-- which deactivates earlier factors in the cascade is known as ___ ___.
Negative Feedback
alloys - passivation
Bioactive
labile cells
15. Keloid scars form due to disfunction of ____.
Free Radical
Collagenase/Remodelling
Bioactive
Phagocytosis
16. Process that makes long fibers (fiber drawing) by forcing a fluid through an oriface.
Plasticizers
Extrusion
Thrombin
alloys - passivation
17. Neutrophils remove bacteria/damaged cell debris from a wound site through the process of ___.
Endothelial cells
phagocytosis
Enzyme cascade
cross - linking
18. A ____ implant is designed to elicit specific - intended to host responses.
Bioactive
Thrombin
Calibration
Heparin
19. The fatigue limit is value of applied stress below which a material will not fail no matter the number of ____ applied.
Mast - Collagen
Damage to cell membranes
cycles
Plastic
20. Relative to free radical polymerization - condensation polymerization generally produces polymer of relatively ____ molecular weight.
Enzyme cascade
low
in cytoplasm
standards of known properties
21. The two types of white blood cells:
scars
Polydesperity index
neutrophils - macrophages
standards of known properties
22. Rather than randomly moving - moves in a directed cell migration manner for specific functions.
Thrombin
Polydesperity index
chemotaxis
Proteases
23. Keloid scars forms because disfuntion of
Polymers - cross linking of polymers
Intermolecular bonding - molecular weight
Collagenase
standards of known properties
24. Vascular endothelial growth factor is produced in response to ___ and stimulates ___.
hypoxin - angiogenesis
Metals
Chemotaxis
Proteases
25. _____ establishes a quantitative relationship between measured output values from an instrument and known standards of what is being measured.
Hemocompatibility
Enzyme cascade
Calibration
Mast - Collagen
26. ____ is a measurement that characterizes the breadth of the distribution of a polymer's molecular weight.
Bioactive
Allogeneic
Endothelial cells
Polydesperity index
27. Thrombin activates several upstream factors.
Positive Feedback
Bioactive
Number of polymers - molecular weight of polymer
Proteases
28. Cells that proliferate slowly over time (aka liver)
Heparin
micromachining
standards of known properties
Stable cells
29. What types of wound healing results from injury with inflammation?
heparin
Negative Feedback
Regeneration/Repair
Higher
30. Enzymes (proteins) are not activated only when they are in contact with this type of cells
Macrophages
Regeneration/Repair
Endothelial cells
Polydesperity index
31. ____ describes the ability of a device to function appropriately in the presence of blood.
Water
Thrombin
Hemocompatibility
mast cells
32. This cleaves into fibrinogen which creates fibrin (a sticky enzyme that allows blood to clot)
Calibration
Thrombin
Large
Damage to cell membranes
33. Essentially all metallic biomaterials are ____ - comprised of two or more metals. One of these metals is selected for its ability to support _____ - the formation of a stable oxide layer that resists further corrosion.
standards of known properties
Extrusion
alloys - passivation
labile cells
34. High conductivity - isotropic - crystalline
Negative Feedback
Metals
phagocytosis
Collagenase
35. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure.
Water
stress
Free Radical
micromachining
36. The formation of rust due to corrosion in the body is due to the reaction between these 3 things ____ - ____ - and ____ .
Damage to cell membranes
Water - oxygen - metal
hypoxin - angiogenesis
Calibration
37. Higher Molecular weight degrades slower than ____ MW
Lower
Hemocompatibility
Positive Feedback
Large
38. Where are the tissue factors found when they're inactivated
Damage to cell membranes
mast cells
in cytoplasm
Hemophilia
39. Enzyme that really gets the polmerization going!
Extrusion
Thrombin
glassy to rubbery
heparin
40. In order to produce a blood clot - thrombin cleaves/activates ____ and ____.
Hemocompatibility
angiogenesis
fibrinogen - factor XIII
Plasticizers
41. The fibrous capsule surrounding a permanent implant is primarily composed of ___ cells and ____ (matrix).
Stable cells
Mast - Collagen
photoactive polymers
binding
42. Foreign body giants cells are produced by fusion of ___.
Negative Feedback
free radical
Macrophages
Collagenase
43. Cell found in the lining of the blood vessels that release heparin and are a part of the negative feedback system.
Amide
photoactive polymers
mast cells
binding
44. Mast cells release this
cycles
binding
heparin
photoactive polymers
45. What type of materials are used for photolithography? (substrate is a silicon wafer - built up material is some _____ ____ )
Water - oxygen - metal
photoactive polymers
Endothelial cells
Stable cells
46. Cells that proliferate rapidly (fibroblasts)
binding
Polymers - cross linking of polymers
Permanent cells
labile cells
47. List two chemical characteristics of polymers:
photoactive polymers
Phagocytosis
Water - oxygen - metal
Intermolecular bonding - molecular weight
48. ____ are enzymes responsible for protein degradation.
Proteases
Extrusion
cycles
Metals
49. Process of producing new blood vessels due to a lack on oxygen and thus inducing VEGF.
scars
angiogenesis
Stress
Polydesperity index
50. The trigger for activation of enzymes (anything but endothelial cells!)
binding
Calibration
hypoxin - angiogenesis
micromachining