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Test your basic knowledge |
Bio Engineering
Start Test
Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Two things needed in the end product of the creation of a scab
Polymers - cross linking of polymers
cross - linking
stress
mast cells
2. Damaged cells at the site of injury (mast cells) release ___ (glycosaminoglycan).
Allogeneic
stress
Lower
heparin
3. ____ is the process by which cells involved in inflammation internalize and destroy foreign material.
free radical
Compression molding
Phagocytosis
fibrinogen - factor XIII
4. ____- are polymers that can be repeatedly softened by heating and hardened by cooling.
phagocytosis
Endothelial cells
Proteases
Thermoplastics
5. ______ Molecular weight degrades slower than lower MW
Collagenase/Remodelling
Negative Feedback
Higher
angiogenesis
6. Keloid scars form due to disfunction of ____.
Intermolecular bonding - molecular weight
Collagenase/Remodelling
Protein Absorption
Thrombin
7. The calculation of a polymer's molecular weight (weight average and number number average) is based upon values for ____ and ___.
Proteases
Stable cells
stress
Number of polymers - molecular weight of polymer
8. Addition polymerization is commonly initiated by ___ - atoms that have an unpaired electron.
Allogeneic
mast cells
free radical
angiogenesis
9. Enzymes (proteins) are not activated only when they are in contact with this type of cells
stress
Endothelial cells
Lower
Negative Feedback
10. The trigger for activation of enzymes (anything but endothelial cells!)
Heparin
stress
Endothelial cells
binding
11. No healing of damage neurons is the result of ____ cells that are not able to ____.
Permanent - replicate
Compression molding
Thermoplastics
free radical
12. ____ is a measurement that characterizes the breadth of the distribution of a polymer's molecular weight.
Polydesperity index
phagocytosis
Proteases
Collagenase/Remodelling
13. Activates tissue factors aka endothelial damage
Compression molding
Large
Damage to cell membranes
Protein Absorption
14. In order to produce a blood clot - thrombin cleaves/activates ____ and ____.
fibrinogen - factor XIII
Large
autologous
Bioactive
15. A molecular pathway in which the product of each reaction catalyzes the subsequent reaction.
Calibration
cycles
alloys - passivation
Enzyme cascade
16. Is directed cell migration in response to a concentration gradient of soluble molecules.
cross - linking
Bioactive
in cytoplasm
Chemotaxis
17. List two chemical characteristics of polymers:
Thermoplastics
Polydesperity index
Intermolecular bonding - molecular weight
Polymers - cross linking of polymers
18. Foreign body giants cells are produced by fusion of ___.
Compression molding
Protein Absorption
Higher
Macrophages
19. Which of polyermization (condensation/free radical) would you choose to obtain a polymer of high molecular weight?
Phagocytosis
Polydesperity index
standards of known properties
Free Radical
20. Deformation that cannot be recovered once the load is removed from the material is ____ deformation.
Intermolecular bonding - molecular weight
Water
cycles
Plastic
21. ____ grafts are derived from the other humans.
Hemocompatibility
binding
heparin
Allogeneic
22. Classify the following polymers into appropriate families based on their bond structure i.e. the polymer is an example of poly ____.
cross - linking
Amide
scars
Stable cells
23. Cells that proliferate slowly over time (aka liver)
Stable cells
Water
Proteases
Regeneration/Repair
24. Vascular endothelial growth factor is produced in response to ___ and stimulates ___.
Intermolecular bonding - molecular weight
Plastic
hypoxin - angiogenesis
Stable cells
25. GPC separates molecules on the basis of size by their passage over a column packed with a porous matrix. ___ molecules pass through the column more quickly.
free radical
Heparin
Large
Macrophages
26. Collagen ____ is responsible for the gradual gain in mechanical properties of wounded tissue between roughly 4 and 52 weeks post- injury.
Damage to cell membranes
cross - linking
Endothelial cells
photoactive polymers
27. A ____ implant is designed to elicit specific - intended to host responses.
Macrophages
Hemophilia
Hemocompatibility
Bioactive
28. The fibrous capsule surrounding a permanent implant is primarily composed of ___ cells and ____ (matrix).
free radical
hypoxin - angiogenesis
Mast - Collagen
Compression molding
29. Process that makes long fibers (fiber drawing) by forcing a fluid through an oriface.
Free Radical
chemotaxis
Extrusion
Intermolecular bonding - molecular weight
30. What types of wound healing results from injury with inflammation?
Collagenase
Water
Regeneration/Repair
Permanent - replicate
31. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure.
micromachining
stress
Metals
cross - linking
32. Higher Molecular weight degrades slower than ____ MW
Lower
Positive Feedback
macrophages - proliferation
Regeneration/Repair
33. Essentially all metallic biomaterials are ____ - comprised of two or more metals. One of these metals is selected for its ability to support _____ - the formation of a stable oxide layer that resists further corrosion.
Free Radical
alloys - passivation
Endothelial cells
neutrophils - macrophages
34. Cells that don't proliferate (neurons)
Thrombin
Water - oxygen - metal
Have to be in a clean room free of dust and biocontamination - expensive
Permanent cells
35. The process of calibration establishes a quantitative relationship between ____ __ ___ _____ and the direct output of the intstrument (for example time/volume in GPC).
Lower
Metals
Polymers - cross linking of polymers
standards of known properties
36. You're working on a square polymeric implant of 5cm length and 2mm thick. You've been asked to suggest a precise way to fabricate it - what would you suggest?
angiogenesis
Polymers - cross linking of polymers
Stable cells
Compression molding
37. Cells that proliferate rapidly (fibroblasts)
chemotaxis
cycles
Negative Feedback
labile cells
38. Type of fiber drawing that controls details of a polymer by etching on a microscopic level; thus - controlling mechanical properties as well
negative feedback
micromachining
Number of polymers - molecular weight of polymer
Enzyme cascade
39. Disfunction of _____ (cells) producing collagenase during the _____ phase of wound healing may form Keloid scars.
negative feedback
angiogenesis
macrophages - proliferation
glassy to rubbery
40. Condition in which patients can literally bleed to death.
Mast - Collagen
Hemophilia
autologous
negative feedback
41. ____ are enzymes responsible for protein degradation.
Proteases
alloys - passivation
Stable cells
Large
42. Are polymer additives used to lower glass transition temperature temperature.
Free Radical
Large
Plasticizers
stress
43. Neutrophils remove bacteria/damaged cell debris from a wound site through the process of ___.
phagocytosis
Metals
Damage to cell membranes
in cytoplasm
44. This cleaves into fibrinogen which creates fibrin (a sticky enzyme that allows blood to clot)
Phagocytosis
Thrombin
Collagenase
fibrinogen - factor XIII
45. Polyethylene oxide grafting to biomaterials was developed to prevent coagulation by interfering with/preventing ___ ___.
autologous
Protein Absorption
Stable cells
fibrinogen - factor XIII
46. The formation of rust due to corrosion in the body is due to the reaction between these 3 things ____ - ____ - and ____ .
Plastic
Heparin
Water - oxygen - metal
Have to be in a clean room free of dust and biocontamination - expensive
47. Resulting from the build up of too much collagen at the surface of injury during the granulation tissue stage of proliferation
Polymers - cross linking of polymers
Calibration
angiogenesis
scars
48. Thrombin also activates protein C-- which deactivates earlier factors in the cascade is known as ___ ___.
Protein Absorption
Negative Feedback
phagocytosis
Large
49. Rather than randomly moving - moves in a directed cell migration manner for specific functions.
Collagenase
chemotaxis
Damage to cell membranes
scars
50. A condensation polymerization results with an ester bond between two reactants and this comes off as a result
negative feedback
Water
macrophages - proliferation
standards of known properties