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Test your basic knowledge |
Bio Engineering
Start Test
Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Cells that proliferate slowly over time (aka liver)
stress
Have to be in a clean room free of dust and biocontamination - expensive
Collagenase/Remodelling
Stable cells
2. Which of polyermization (condensation/free radical) would you choose to obtain a polymer of high molecular weight?
Metals
cross - linking
Have to be in a clean room free of dust and biocontamination - expensive
Free Radical
3. Deformation that cannot be recovered once the load is removed from the material is ____ deformation.
Phagocytosis
stress
Plastic
cycles
4. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure
binding
Stress
angiogenesis
Allogeneic
5. You're working on a square polymeric implant of 5cm length and 2mm thick. You've been asked to suggest a precise way to fabricate it - what would you suggest?
Water - oxygen - metal
Amide
alloys - passivation
Compression molding
6. Cells that don't proliferate (neurons)
neutrophils - macrophages
Thrombin
Permanent cells
Heparin
7. Disfunction of _____ (cells) producing collagenase during the _____ phase of wound healing may form Keloid scars.
Damage to cell membranes
macrophages - proliferation
Water
Plasticizers
8. Classify the following polymers into appropriate families based on their bond structure i.e. the polymer is an example of poly ____.
alloys - passivation
Amide
Calibration
Phagocytosis
9. Addition polymerization is commonly initiated by ___ - atoms that have an unpaired electron.
Damage to cell membranes
Mast - Collagen
Large
free radical
10. ____- are polymers that can be repeatedly softened by heating and hardened by cooling.
hypoxin - angiogenesis
Water - oxygen - metal
Thermoplastics
Plastic
11. Vascular endothelial growth factor is produced in response to ___ and stimulates ___.
Positive Feedback
Macrophages
hypoxin - angiogenesis
glassy to rubbery
12. The glass transition temperature of a poymer at which a polymer transforms from a ____ state to a ___ state.
Phagocytosis
Collagenase/Remodelling
Water
glassy to rubbery
13. Condition in which patients can literally bleed to death.
Permanent - replicate
Enzyme cascade
Proteases
Hemophilia
14. GPC separates molecules on the basis of size by their passage over a column packed with a porous matrix. ___ molecules pass through the column more quickly.
chemotaxis
binding
Large
Lower
15. Cells that proliferate rapidly (fibroblasts)
labile cells
Macrophages
macrophages - proliferation
cross - linking
16. ____ are enzymes responsible for protein degradation.
Allogeneic
Intermolecular bonding - molecular weight
Stable cells
Proteases
17. Polyethylene oxide grafting to biomaterials was developed to prevent coagulation by interfering with/preventing ___ ___.
in cytoplasm
micromachining
Permanent - replicate
Protein Absorption
18. The calculation of a polymer's molecular weight (weight average and number number average) is based upon values for ____ and ___.
standards of known properties
phagocytosis
Number of polymers - molecular weight of polymer
Mast - Collagen
19. ____ is a measurement that characterizes the breadth of the distribution of a polymer's molecular weight.
stress
Mast - Collagen
Collagenase/Remodelling
Polydesperity index
20. Cell found in the lining of the blood vessels that release heparin and are a part of the negative feedback system.
Thermoplastics
Allogeneic
mast cells
Hemophilia
21. Relative to free radical polymerization - condensation polymerization generally produces polymer of relatively ____ molecular weight.
scars
Heparin
Hemophilia
low
22. Thrombin activates several upstream factors.
Hemophilia
Positive Feedback
Proteases
Collagenase
23. The process of calibration establishes a quantitative relationship between ____ __ ___ _____ and the direct output of the intstrument (for example time/volume in GPC).
Higher
standards of known properties
Thrombin
hypoxin - angiogenesis
24. Resulting from the build up of too much collagen at the surface of injury during the granulation tissue stage of proliferation
Lower
Damage to cell membranes
scars
Endothelial cells
25. Thrombin also activates protein C-- which deactivates earlier factors in the cascade is known as ___ ___.
Negative Feedback
Permanent cells
Metals
Mast - Collagen
26. Are polymer additives used to lower glass transition temperature temperature.
Thrombin
hypoxin - angiogenesis
Plasticizers
heparin
27. High conductivity - isotropic - crystalline
stress
Higher
Metals
chemotaxis
28. Neutrophils remove bacteria/damaged cell debris from a wound site through the process of ___.
Number of polymers - molecular weight of polymer
phagocytosis
Free Radical
Thrombin
29. List two chemical characteristics of polymers:
Collagenase
Enzyme cascade
scars
Intermolecular bonding - molecular weight
30. Two things needed in the end product of the creation of a scab
Polymers - cross linking of polymers
angiogenesis
Positive Feedback
Plastic
31. Where are the tissue factors found when they're inactivated
autologous
Polydesperity index
in cytoplasm
Water
32. Enzymes (proteins) are not activated only when they are in contact with this type of cells
chemotaxis
Endothelial cells
mast cells
Water - oxygen - metal
33. Cardiac bypass surgery in which a vein from a patient's leg is transplanted to the patient's heart is an example of the us of ____ tissue.
autologous
Regeneration/Repair
Collagenase/Remodelling
Mast - Collagen
34. Mast cells release this
cycles
Lower
Metals
heparin
35. The fibrous capsule surrounding a permanent implant is primarily composed of ___ cells and ____ (matrix).
macrophages - proliferation
Mast - Collagen
Polymers - cross linking of polymers
Large
36. During granulation stage of proliferation - growth factors that produce this ____(answer)_____ that function in degrading fibrin and replacing it with collagen.
Stable cells
Proteases
Regeneration/Repair
heparin
37. What types of wound healing results from injury with inflammation?
Protein Absorption
Regeneration/Repair
Negative Feedback
Intermolecular bonding - molecular weight
38. A condensation polymerization results with an ester bond between two reactants and this comes off as a result
Polymers - cross linking of polymers
micromachining
Water
Number of polymers - molecular weight of polymer
39. A ____ implant is designed to elicit specific - intended to host responses.
heparin
autologous
Bioactive
cycles
40. ____ describes the ability of a device to function appropriately in the presence of blood.
hypoxin - angiogenesis
heparin
Hemocompatibility
stress
41. The formation of rust due to corrosion in the body is due to the reaction between these 3 things ____ - ____ - and ____ .
Water - oxygen - metal
Proteases
Stress
Bioactive
42. Process that makes long fibers (fiber drawing) by forcing a fluid through an oriface.
Extrusion
Higher
cross - linking
glassy to rubbery
43. Collagen ____ is responsible for the gradual gain in mechanical properties of wounded tissue between roughly 4 and 52 weeks post- injury.
cross - linking
photoactive polymers
Thrombin
Bioactive
44. Damaged cells at the site of injury (mast cells) release ___ (glycosaminoglycan).
Compression molding
heparin
glassy to rubbery
Polymers - cross linking of polymers
45. Keloid scars form due to disfunction of ____.
negative feedback
Higher
Stress
Collagenase/Remodelling
46. In order to produce a blood clot - thrombin cleaves/activates ____ and ____.
Have to be in a clean room free of dust and biocontamination - expensive
fibrinogen - factor XIII
Plasticizers
Thermoplastics
47. Type of fiber drawing that controls details of a polymer by etching on a microscopic level; thus - controlling mechanical properties as well
Hemophilia
Proteases
micromachining
Proteases
48. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure.
Negative Feedback
stress
Protein Absorption
Permanent cells
49. ____ binds to anti- thrombin III (thrombin inhibitor) and increases its potency 1000- fold.
negative feedback
stress
Heparin
in cytoplasm
50. Process of producing new blood vessels due to a lack on oxygen and thus inducing VEGF.
Free Radical
scars
angiogenesis
hypoxin - angiogenesis