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Test your basic knowledge |
Bio Engineering
Start Test
Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Higher Molecular weight degrades slower than ____ MW
negative feedback
Lower
Endothelial cells
heparin
2. Cell found in the lining of the blood vessels that release heparin and are a part of the negative feedback system.
mast cells
Proteases
Have to be in a clean room free of dust and biocontamination - expensive
Positive Feedback
3. Cells that proliferate slowly over time (aka liver)
Stable cells
Enzyme cascade
Thrombin
Thrombin
4. The trigger for activation of enzymes (anything but endothelial cells!)
cross - linking
Higher
cycles
binding
5. Condition in which patients can literally bleed to death.
Intermolecular bonding - molecular weight
Water - oxygen - metal
Bioactive
Hemophilia
6. Activates tissue factors aka endothelial damage
Proteases
Damage to cell membranes
Bioactive
Thermoplastics
7. ____ binds to anti- thrombin III (thrombin inhibitor) and increases its potency 1000- fold.
Heparin
Proteases
Polydesperity index
Thrombin
8. List two chemical characteristics of polymers:
Intermolecular bonding - molecular weight
Enzyme cascade
free radical
Plastic
9. You're working on a square polymeric implant of 5cm length and 2mm thick. You've been asked to suggest a precise way to fabricate it - what would you suggest?
in cytoplasm
Compression molding
Water
Lower
10. Process that makes long fibers (fiber drawing) by forcing a fluid through an oriface.
Extrusion
standards of known properties
fibrinogen - factor XIII
macrophages - proliferation
11. Are polymer additives used to lower glass transition temperature temperature.
heparin
Endothelial cells
Plasticizers
Allogeneic
12. Addition polymerization is commonly initiated by ___ - atoms that have an unpaired electron.
free radical
low
Damage to cell membranes
Calibration
13. Enzymes (proteins) are not activated only when they are in contact with this type of cells
Endothelial cells
angiogenesis
Phagocytosis
labile cells
14. Relative to free radical polymerization - condensation polymerization generally produces polymer of relatively ____ molecular weight.
Collagenase/Remodelling
Water
Protein Absorption
low
15. During granulation stage of proliferation - growth factors that produce this ____(answer)_____ that function in degrading fibrin and replacing it with collagen.
Proteases
Regeneration/Repair
Damage to cell membranes
micromachining
16. Classify the following polymers into appropriate families based on their bond structure i.e. the polymer is an example of poly ____.
Phagocytosis
Metals
Permanent - replicate
Amide
17. Keloid scars form due to disfunction of ____.
Collagenase/Remodelling
Lower
Macrophages
Enzyme cascade
18. _____ establishes a quantitative relationship between measured output values from an instrument and known standards of what is being measured.
Intermolecular bonding - molecular weight
standards of known properties
Bioactive
Calibration
19. The fatigue limit is value of applied stress below which a material will not fail no matter the number of ____ applied.
cycles
Plastic
Intermolecular bonding - molecular weight
Extrusion
20. Process of producing new blood vessels due to a lack on oxygen and thus inducing VEGF.
photoactive polymers
Hemophilia
angiogenesis
Damage to cell membranes
21. Thrombin also activates protein C-- which deactivates earlier factors in the cascade is known as ___ ___.
Negative Feedback
Mast - Collagen
hypoxin - angiogenesis
macrophages - proliferation
22. A condensation polymerization results with an ester bond between two reactants and this comes off as a result
macrophages - proliferation
Water
phagocytosis
Collagenase
23. This cleaves into fibrinogen which creates fibrin (a sticky enzyme that allows blood to clot)
Chemotaxis
photoactive polymers
Thrombin
scars
24. ____ describes the ability of a device to function appropriately in the presence of blood.
Collagenase/Remodelling
chemotaxis
Negative Feedback
Hemocompatibility
25. The fibrous capsule surrounding a permanent implant is primarily composed of ___ cells and ____ (matrix).
Positive Feedback
Mast - Collagen
Thrombin
standards of known properties
26. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure.
heparin
stress
Damage to cell membranes
micromachining
27. Polyethylene oxide grafting to biomaterials was developed to prevent coagulation by interfering with/preventing ___ ___.
Protein Absorption
mast cells
heparin
Negative Feedback
28. The process of calibration establishes a quantitative relationship between ____ __ ___ _____ and the direct output of the intstrument (for example time/volume in GPC).
Stable cells
heparin
standards of known properties
neutrophils - macrophages
29. Essentially all metallic biomaterials are ____ - comprised of two or more metals. One of these metals is selected for its ability to support _____ - the formation of a stable oxide layer that resists further corrosion.
alloys - passivation
Intermolecular bonding - molecular weight
cycles
Thrombin
30. Rather than randomly moving - moves in a directed cell migration manner for specific functions.
chemotaxis
Permanent cells
heparin
labile cells
31. Resulting from the build up of too much collagen at the surface of injury during the granulation tissue stage of proliferation
neutrophils - macrophages
Plastic
scars
Damage to cell membranes
32. A ____ implant is designed to elicit specific - intended to host responses.
heparin
Endothelial cells
Positive Feedback
Bioactive
33. ____ is the process by which cells involved in inflammation internalize and destroy foreign material.
Phagocytosis
Polymers - cross linking of polymers
Chemotaxis
labile cells
34. Collagen ____ is responsible for the gradual gain in mechanical properties of wounded tissue between roughly 4 and 52 weeks post- injury.
cross - linking
stress
Hemocompatibility
Macrophages
35. Foreign body giants cells are produced by fusion of ___.
Macrophages
scars
Compression molding
Mast - Collagen
36. GPC separates molecules on the basis of size by their passage over a column packed with a porous matrix. ___ molecules pass through the column more quickly.
Bioactive
phagocytosis
autologous
Large
37. Cells that proliferate rapidly (fibroblasts)
macrophages - proliferation
negative feedback
labile cells
Collagenase
38. What types of wound healing results from injury with inflammation?
Enzyme cascade
Metals
stress
Regeneration/Repair
39. Drawback of micromaching
Chemotaxis
Stable cells
Have to be in a clean room free of dust and biocontamination - expensive
Intermolecular bonding - molecular weight
40. Cells that don't proliferate (neurons)
Collagenase
hypoxin - angiogenesis
mast cells
Permanent cells
41. Vascular endothelial growth factor is produced in response to ___ and stimulates ___.
Compression molding
hypoxin - angiogenesis
Negative Feedback
Hemophilia
42. ____ is a measurement that characterizes the breadth of the distribution of a polymer's molecular weight.
scars
low
Allogeneic
Polydesperity index
43. The formation of rust due to corrosion in the body is due to the reaction between these 3 things ____ - ____ - and ____ .
low
glassy to rubbery
Water - oxygen - metal
Positive Feedback
44. This type of feedback creates
Enzyme cascade
negative feedback
Polydesperity index
Hemocompatibility
45. Which of polyermization (condensation/free radical) would you choose to obtain a polymer of high molecular weight?
Permanent cells
Allogeneic
Free Radical
Thrombin
46. Enzyme that really gets the polmerization going!
neutrophils - macrophages
Thrombin
Stable cells
phagocytosis
47. Two things needed in the end product of the creation of a scab
Positive Feedback
free radical
Polymers - cross linking of polymers
Stress
48. Is directed cell migration in response to a concentration gradient of soluble molecules.
Allogeneic
Collagenase/Remodelling
Chemotaxis
heparin
49. Neutrophils remove bacteria/damaged cell debris from a wound site through the process of ___.
autologous
Macrophages
phagocytosis
Heparin
50. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure
binding
Collagenase
Stress
Collagenase/Remodelling