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Test your basic knowledge |
Bio Engineering
Start Test
Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Rather than randomly moving - moves in a directed cell migration manner for specific functions.
Endothelial cells
Amide
chemotaxis
Collagenase/Remodelling
2. ____ is the process by which cells involved in inflammation internalize and destroy foreign material.
alloys - passivation
Hemocompatibility
Phagocytosis
Heparin
3. You're working on a square polymeric implant of 5cm length and 2mm thick. You've been asked to suggest a precise way to fabricate it - what would you suggest?
glassy to rubbery
Stress
Phagocytosis
Compression molding
4. ____ binds to anti- thrombin III (thrombin inhibitor) and increases its potency 1000- fold.
photoactive polymers
angiogenesis
Heparin
stress
5. The calculation of a polymer's molecular weight (weight average and number number average) is based upon values for ____ and ___.
Number of polymers - molecular weight of polymer
low
Positive Feedback
Free Radical
6. Neutrophils remove bacteria/damaged cell debris from a wound site through the process of ___.
Regeneration/Repair
Amide
Stable cells
phagocytosis
7. Cell found in the lining of the blood vessels that release heparin and are a part of the negative feedback system.
mast cells
Plastic
neutrophils - macrophages
negative feedback
8. Which of polyermization (condensation/free radical) would you choose to obtain a polymer of high molecular weight?
Calibration
Free Radical
cycles
Thrombin
9. Vascular endothelial growth factor is produced in response to ___ and stimulates ___.
Thrombin
labile cells
hypoxin - angiogenesis
Large
10. Process that makes long fibers (fiber drawing) by forcing a fluid through an oriface.
Extrusion
Permanent cells
Chemotaxis
Allogeneic
11. What type of materials are used for photolithography? (substrate is a silicon wafer - built up material is some _____ ____ )
Have to be in a clean room free of dust and biocontamination - expensive
Thermoplastics
Endothelial cells
photoactive polymers
12. Thrombin also activates protein C-- which deactivates earlier factors in the cascade is known as ___ ___.
Negative Feedback
labile cells
in cytoplasm
cross - linking
13. What types of wound healing results from injury with inflammation?
Plasticizers
heparin
Regeneration/Repair
negative feedback
14. Cardiac bypass surgery in which a vein from a patient's leg is transplanted to the patient's heart is an example of the us of ____ tissue.
autologous
angiogenesis
hypoxin - angiogenesis
standards of known properties
15. Higher Molecular weight degrades slower than ____ MW
scars
Lower
Proteases
Bioactive
16. ____ are enzymes responsible for protein degradation.
Chemotaxis
phagocytosis
Lower
Proteases
17. The two types of white blood cells:
Plastic
Enzyme cascade
mast cells
neutrophils - macrophages
18. Where are the tissue factors found when they're inactivated
Chemotaxis
in cytoplasm
heparin
Hemocompatibility
19. ______ Molecular weight degrades slower than lower MW
Proteases
Thermoplastics
Higher
Phagocytosis
20. Process of producing new blood vessels due to a lack on oxygen and thus inducing VEGF.
labile cells
angiogenesis
Free Radical
Phagocytosis
21. This type of feedback creates
negative feedback
Permanent - replicate
heparin
Plasticizers
22. ____- are polymers that can be repeatedly softened by heating and hardened by cooling.
Water
Higher
chemotaxis
Thermoplastics
23. Enzymes (proteins) are not activated only when they are in contact with this type of cells
Endothelial cells
Polymers - cross linking of polymers
Permanent cells
Plastic
24. During granulation stage of proliferation - growth factors that produce this ____(answer)_____ that function in degrading fibrin and replacing it with collagen.
Protein Absorption
Regeneration/Repair
Lower
Proteases
25. Keloid scars form due to disfunction of ____.
Negative Feedback
Collagenase/Remodelling
Proteases
Proteases
26. ____ is a measurement that characterizes the breadth of the distribution of a polymer's molecular weight.
Polydesperity index
autologous
Have to be in a clean room free of dust and biocontamination - expensive
hypoxin - angiogenesis
27. Cells that proliferate rapidly (fibroblasts)
low
Thrombin
labile cells
photoactive polymers
28. High conductivity - isotropic - crystalline
stress
Mast - Collagen
Metals
Heparin
29. In order to produce a blood clot - thrombin cleaves/activates ____ and ____.
fibrinogen - factor XIII
Chemotaxis
cycles
Stable cells
30. Relative to free radical polymerization - condensation polymerization generally produces polymer of relatively ____ molecular weight.
Higher
low
Metals
Water - oxygen - metal
31. List two chemical characteristics of polymers:
Intermolecular bonding - molecular weight
Plastic
Thrombin
Chemotaxis
32. ____ grafts are derived from the other humans.
stress
Stress
labile cells
Allogeneic
33. Two things needed in the end product of the creation of a scab
Regeneration/Repair
cross - linking
angiogenesis
Polymers - cross linking of polymers
34. Condition in which patients can literally bleed to death.
Hemophilia
scars
Intermolecular bonding - molecular weight
Hemocompatibility
35. Activates tissue factors aka endothelial damage
Mast - Collagen
Metals
Compression molding
Damage to cell membranes
36. Is directed cell migration in response to a concentration gradient of soluble molecules.
Bioactive
Positive Feedback
Metals
Chemotaxis
37. Classify the following polymers into appropriate families based on their bond structure i.e. the polymer is an example of poly ____.
micromachining
Amide
angiogenesis
Permanent cells
38. A molecular pathway in which the product of each reaction catalyzes the subsequent reaction.
in cytoplasm
Polymers - cross linking of polymers
standards of known properties
Enzyme cascade
39. Collagen ____ is responsible for the gradual gain in mechanical properties of wounded tissue between roughly 4 and 52 weeks post- injury.
cross - linking
alloys - passivation
Intermolecular bonding - molecular weight
hypoxin - angiogenesis
40. Foreign body giants cells are produced by fusion of ___.
Hemocompatibility
Polydesperity index
Macrophages
fibrinogen - factor XIII
41. Essentially all metallic biomaterials are ____ - comprised of two or more metals. One of these metals is selected for its ability to support _____ - the formation of a stable oxide layer that resists further corrosion.
alloys - passivation
neutrophils - macrophages
Lower
Higher
42. This cleaves into fibrinogen which creates fibrin (a sticky enzyme that allows blood to clot)
Thrombin
Collagenase/Remodelling
negative feedback
Number of polymers - molecular weight of polymer
43. Drawback of micromaching
Higher
stress
Have to be in a clean room free of dust and biocontamination - expensive
Collagenase/Remodelling
44. ____ describes the ability of a device to function appropriately in the presence of blood.
Hemocompatibility
Plasticizers
Have to be in a clean room free of dust and biocontamination - expensive
hypoxin - angiogenesis
45. Keloid scars forms because disfuntion of
autologous
Water
Permanent - replicate
Collagenase
46. A condensation polymerization results with an ester bond between two reactants and this comes off as a result
Damage to cell membranes
phagocytosis
Calibration
Water
47. The trigger for activation of enzymes (anything but endothelial cells!)
Polymers - cross linking of polymers
mast cells
binding
Water
48. Disfunction of _____ (cells) producing collagenase during the _____ phase of wound healing may form Keloid scars.
macrophages - proliferation
alloys - passivation
Allogeneic
binding
49. A ____ implant is designed to elicit specific - intended to host responses.
Free Radical
Positive Feedback
Number of polymers - molecular weight of polymer
Bioactive
50. Resulting from the build up of too much collagen at the surface of injury during the granulation tissue stage of proliferation
scars
photoactive polymers
Phagocytosis
hypoxin - angiogenesis