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Bio Engineering

Subject : engineering
  • Answer 50 questions in 15 minutes.
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  • Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Process that makes long fibers (fiber drawing) by forcing a fluid through an oriface.

2. Drawback of micromaching

3. Polyethylene oxide grafting to biomaterials was developed to prevent coagulation by interfering with/preventing ___ ___.

4. This cleaves into fibrinogen which creates fibrin (a sticky enzyme that allows blood to clot)

5. Vascular endothelial growth factor is produced in response to ___ and stimulates ___.

6. ____ binds to anti- thrombin III (thrombin inhibitor) and increases its potency 1000- fold.

7. Condition in which patients can literally bleed to death.

8. Collagen ____ is responsible for the gradual gain in mechanical properties of wounded tissue between roughly 4 and 52 weeks post- injury.

9. You're working on a square polymeric implant of 5cm length and 2mm thick. You've been asked to suggest a precise way to fabricate it - what would you suggest?

10. GPC separates molecules on the basis of size by their passage over a column packed with a porous matrix. ___ molecules pass through the column more quickly.

11. ____ are enzymes responsible for protein degradation.

12. No healing of damage neurons is the result of ____ cells that are not able to ____.

13. Activates tissue factors aka endothelial damage

14. What type of materials are used for photolithography? (substrate is a silicon wafer - built up material is some _____ ____ )

15. This type of feedback creates

16. Which of polyermization (condensation/free radical) would you choose to obtain a polymer of high molecular weight?

17. The formation of rust due to corrosion in the body is due to the reaction between these 3 things ____ - ____ - and ____ .

18. The fibrous capsule surrounding a permanent implant is primarily composed of ___ cells and ____ (matrix).

19. Disfunction of _____ (cells) producing collagenase during the _____ phase of wound healing may form Keloid scars.

20. Higher Molecular weight degrades slower than ____ MW

21. Cardiac bypass surgery in which a vein from a patient's leg is transplanted to the patient's heart is an example of the us of ____ tissue.

22. What types of wound healing results from injury with inflammation?

23. Cells that proliferate slowly over time (aka liver)

24. _____ establishes a quantitative relationship between measured output values from an instrument and known standards of what is being measured.

25. Cells that don't proliferate (neurons)

26. Are polymer additives used to lower glass transition temperature temperature.

27. The trigger for activation of enzymes (anything but endothelial cells!)

28. The calculation of a polymer's molecular weight (weight average and number number average) is based upon values for ____ and ___.

29. ____ grafts are derived from the other humans.

30. Essentially all metallic biomaterials are ____ - comprised of two or more metals. One of these metals is selected for its ability to support _____ - the formation of a stable oxide layer that resists further corrosion.

31. List two chemical characteristics of polymers:

32. A ____ implant is designed to elicit specific - intended to host responses.

33. Damaged cells at the site of injury (mast cells) release ___ (glycosaminoglycan).

34. The process of calibration establishes a quantitative relationship between ____ __ ___ _____ and the direct output of the intstrument (for example time/volume in GPC).

35. ______ Molecular weight degrades slower than lower MW

36. Rather than randomly moving - moves in a directed cell migration manner for specific functions.

37. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure

38. The fatigue limit is value of applied stress below which a material will not fail no matter the number of ____ applied.

39. A molecular pathway in which the product of each reaction catalyzes the subsequent reaction.

40. Relative to free radical polymerization - condensation polymerization generally produces polymer of relatively ____ molecular weight.

41. Thrombin also activates protein C-- which deactivates earlier factors in the cascade is known as ___ ___.

42. High conductivity - isotropic - crystalline

43. Thrombin activates several upstream factors.

44. In order to produce a blood clot - thrombin cleaves/activates ____ and ____.

45. Where are the tissue factors found when they're inactivated

46. Cells that proliferate rapidly (fibroblasts)

47. Enzymes (proteins) are not activated only when they are in contact with this type of cells

48. Process of producing new blood vessels due to a lack on oxygen and thus inducing VEGF.

49. Cell found in the lining of the blood vessels that release heparin and are a part of the negative feedback system.

50. Type of fiber drawing that controls details of a polymer by etching on a microscopic level; thus - controlling mechanical properties as well