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Bio Engineering
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Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
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.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. This cleaves into fibrinogen which creates fibrin (a sticky enzyme that allows blood to clot)
neutrophils - macrophages
Thrombin
Enzyme cascade
alloys - passivation
2. Cells that proliferate rapidly (fibroblasts)
labile cells
Hemocompatibility
Permanent cells
Higher
3. A condensation polymerization results with an ester bond between two reactants and this comes off as a result
Proteases
macrophages - proliferation
Higher
Water
4. Enzyme that really gets the polmerization going!
micromachining
Bioactive
Thrombin
Extrusion
5. ______ Molecular weight degrades slower than lower MW
Higher
Proteases
Polymers - cross linking of polymers
Water - oxygen - metal
6. The glass transition temperature of a poymer at which a polymer transforms from a ____ state to a ___ state.
in cytoplasm
Amide
Plasticizers
glassy to rubbery
7. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure
phagocytosis
Stress
Permanent cells
neutrophils - macrophages
8. No healing of damage neurons is the result of ____ cells that are not able to ____.
Extrusion
Permanent - replicate
Collagenase/Remodelling
Free Radical
9. The formation of rust due to corrosion in the body is due to the reaction between these 3 things ____ - ____ - and ____ .
Collagenase
Water - oxygen - metal
Stable cells
Compression molding
10. Cells that don't proliferate (neurons)
in cytoplasm
hypoxin - angiogenesis
Permanent cells
Water - oxygen - metal
11. Thrombin also activates protein C-- which deactivates earlier factors in the cascade is known as ___ ___.
Amide
Water - oxygen - metal
Collagenase
Negative Feedback
12. Is directed cell migration in response to a concentration gradient of soluble molecules.
Phagocytosis
Chemotaxis
Extrusion
phagocytosis
13. The trigger for activation of enzymes (anything but endothelial cells!)
photoactive polymers
fibrinogen - factor XIII
binding
phagocytosis
14. Drawback of micromaching
Compression molding
scars
cycles
Have to be in a clean room free of dust and biocontamination - expensive
15. ____ describes the ability of a device to function appropriately in the presence of blood.
Damage to cell membranes
low
heparin
Hemocompatibility
16. Rather than randomly moving - moves in a directed cell migration manner for specific functions.
Permanent cells
Proteases
standards of known properties
chemotaxis
17. ____ are enzymes responsible for protein degradation.
Extrusion
scars
Proteases
Regeneration/Repair
18. During granulation stage of proliferation - growth factors that produce this ____(answer)_____ that function in degrading fibrin and replacing it with collagen.
Proteases
Intermolecular bonding - molecular weight
Stress
Have to be in a clean room free of dust and biocontamination - expensive
19. List two chemical characteristics of polymers:
macrophages - proliferation
autologous
binding
Intermolecular bonding - molecular weight
20. What types of wound healing results from injury with inflammation?
Proteases
Enzyme cascade
Regeneration/Repair
Amide
21. Classify the following polymers into appropriate families based on their bond structure i.e. the polymer is an example of poly ____.
stress
Intermolecular bonding - molecular weight
Amide
Proteases
22. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure.
labile cells
Collagenase/Remodelling
stress
negative feedback
23. Resulting from the build up of too much collagen at the surface of injury during the granulation tissue stage of proliferation
Negative Feedback
Higher
scars
angiogenesis
24. Vascular endothelial growth factor is produced in response to ___ and stimulates ___.
labile cells
Thrombin
Polydesperity index
hypoxin - angiogenesis
25. Polyethylene oxide grafting to biomaterials was developed to prevent coagulation by interfering with/preventing ___ ___.
mast cells
Hemocompatibility
Protein Absorption
Stable cells
26. Thrombin activates several upstream factors.
Positive Feedback
Permanent cells
Amide
Protein Absorption
27. The fibrous capsule surrounding a permanent implant is primarily composed of ___ cells and ____ (matrix).
Amide
Mast - Collagen
Free Radical
Regeneration/Repair
28. Damaged cells at the site of injury (mast cells) release ___ (glycosaminoglycan).
heparin
Intermolecular bonding - molecular weight
Water - oxygen - metal
Plastic
29. Two things needed in the end product of the creation of a scab
hypoxin - angiogenesis
Permanent cells
Have to be in a clean room free of dust and biocontamination - expensive
Polymers - cross linking of polymers
30. GPC separates molecules on the basis of size by their passage over a column packed with a porous matrix. ___ molecules pass through the column more quickly.
Collagenase
Large
Hemocompatibility
cross - linking
31. Keloid scars forms because disfuntion of
Collagenase
Positive Feedback
Polymers - cross linking of polymers
angiogenesis
32. The process of calibration establishes a quantitative relationship between ____ __ ___ _____ and the direct output of the intstrument (for example time/volume in GPC).
standards of known properties
Protein Absorption
free radical
Extrusion
33. ____ is a measurement that characterizes the breadth of the distribution of a polymer's molecular weight.
negative feedback
fibrinogen - factor XIII
Polydesperity index
Mast - Collagen
34. ____ grafts are derived from the other humans.
heparin
angiogenesis
Collagenase
Allogeneic
35. Process of producing new blood vessels due to a lack on oxygen and thus inducing VEGF.
angiogenesis
Collagenase/Remodelling
Enzyme cascade
stress
36. Collagen ____ is responsible for the gradual gain in mechanical properties of wounded tissue between roughly 4 and 52 weeks post- injury.
Enzyme cascade
cross - linking
free radical
Thermoplastics
37. Which of polyermization (condensation/free radical) would you choose to obtain a polymer of high molecular weight?
negative feedback
angiogenesis
Free Radical
Intermolecular bonding - molecular weight
38. Condition in which patients can literally bleed to death.
Hemophilia
negative feedback
Damage to cell membranes
micromachining
39. Addition polymerization is commonly initiated by ___ - atoms that have an unpaired electron.
free radical
Amide
low
Lower
40. The two types of white blood cells:
Higher
standards of known properties
neutrophils - macrophages
Water
41. Neutrophils remove bacteria/damaged cell debris from a wound site through the process of ___.
Permanent - replicate
free radical
Macrophages
phagocytosis
42. Cardiac bypass surgery in which a vein from a patient's leg is transplanted to the patient's heart is an example of the us of ____ tissue.
autologous
free radical
Intermolecular bonding - molecular weight
chemotaxis
43. Relative to free radical polymerization - condensation polymerization generally produces polymer of relatively ____ molecular weight.
Lower
low
Proteases
glassy to rubbery
44. Higher Molecular weight degrades slower than ____ MW
Heparin
Lower
standards of known properties
photoactive polymers
45. ____ is the process by which cells involved in inflammation internalize and destroy foreign material.
standards of known properties
macrophages - proliferation
Plasticizers
Phagocytosis
46. This type of feedback creates
Extrusion
negative feedback
Intermolecular bonding - molecular weight
neutrophils - macrophages
47. Where are the tissue factors found when they're inactivated
Polydesperity index
Intermolecular bonding - molecular weight
Macrophages
in cytoplasm
48. The calculation of a polymer's molecular weight (weight average and number number average) is based upon values for ____ and ___.
heparin
Number of polymers - molecular weight of polymer
autologous
Thermoplastics
49. Are polymer additives used to lower glass transition temperature temperature.
Plasticizers
Allogeneic
Stable cells
Water - oxygen - metal
50. Cell found in the lining of the blood vessels that release heparin and are a part of the negative feedback system.
Stable cells
Number of polymers - molecular weight of polymer
mast cells
Hemophilia
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