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Test your basic knowledge |
Bio Engineering
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Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Rather than randomly moving - moves in a directed cell migration manner for specific functions.
photoactive polymers
heparin
chemotaxis
Polymers - cross linking of polymers
2. Relative to free radical polymerization - condensation polymerization generally produces polymer of relatively ____ molecular weight.
Compression molding
Plastic
low
Higher
3. Damaged cells at the site of injury (mast cells) release ___ (glycosaminoglycan).
Mast - Collagen
heparin
Hemophilia
Enzyme cascade
4. Condition in which patients can literally bleed to death.
Protein Absorption
photoactive polymers
Hemophilia
Higher
5. Keloid scars form due to disfunction of ____.
Thrombin
Positive Feedback
chemotaxis
Collagenase/Remodelling
6. What types of wound healing results from injury with inflammation?
Proteases
Regeneration/Repair
macrophages - proliferation
low
7. Cells that proliferate rapidly (fibroblasts)
labile cells
Water
Permanent cells
Regeneration/Repair
8. What type of materials are used for photolithography? (substrate is a silicon wafer - built up material is some _____ ____ )
Water - oxygen - metal
photoactive polymers
Negative Feedback
Amide
9. ____- are polymers that can be repeatedly softened by heating and hardened by cooling.
Thermoplastics
micromachining
Free Radical
Protein Absorption
10. A ____ implant is designed to elicit specific - intended to host responses.
Have to be in a clean room free of dust and biocontamination - expensive
Bioactive
glassy to rubbery
Mast - Collagen
11. Process that makes long fibers (fiber drawing) by forcing a fluid through an oriface.
Extrusion
angiogenesis
Phagocytosis
Proteases
12. The two types of white blood cells:
hypoxin - angiogenesis
neutrophils - macrophages
Permanent cells
Higher
13. Drawback of micromaching
Permanent cells
Metals
Hemophilia
Have to be in a clean room free of dust and biocontamination - expensive
14. ____ describes the ability of a device to function appropriately in the presence of blood.
Free Radical
Endothelial cells
photoactive polymers
Hemocompatibility
15. Thrombin also activates protein C-- which deactivates earlier factors in the cascade is known as ___ ___.
Large
Negative Feedback
Stress
scars
16. The process of calibration establishes a quantitative relationship between ____ __ ___ _____ and the direct output of the intstrument (for example time/volume in GPC).
labile cells
Bioactive
Chemotaxis
standards of known properties
17. Cells that proliferate slowly over time (aka liver)
angiogenesis
Stable cells
mast cells
Chemotaxis
18. Addition polymerization is commonly initiated by ___ - atoms that have an unpaired electron.
cross - linking
free radical
negative feedback
Water - oxygen - metal
19. Enzyme that really gets the polmerization going!
Phagocytosis
Lower
fibrinogen - factor XIII
Thrombin
20. Enzymes (proteins) are not activated only when they are in contact with this type of cells
Permanent - replicate
heparin
Lower
Endothelial cells
21. Process of producing new blood vessels due to a lack on oxygen and thus inducing VEGF.
Enzyme cascade
Protein Absorption
angiogenesis
free radical
22. Activates tissue factors aka endothelial damage
heparin
Damage to cell membranes
Higher
cycles
23. A molecular pathway in which the product of each reaction catalyzes the subsequent reaction.
Phagocytosis
Water - oxygen - metal
Enzyme cascade
Heparin
24. ____ binds to anti- thrombin III (thrombin inhibitor) and increases its potency 1000- fold.
Regeneration/Repair
Heparin
Negative Feedback
chemotaxis
25. Vascular endothelial growth factor is produced in response to ___ and stimulates ___.
micromachining
Stable cells
hypoxin - angiogenesis
Large
26. Cardiac bypass surgery in which a vein from a patient's leg is transplanted to the patient's heart is an example of the us of ____ tissue.
Plasticizers
phagocytosis
autologous
Extrusion
27. Cell found in the lining of the blood vessels that release heparin and are a part of the negative feedback system.
Collagenase/Remodelling
mast cells
Regeneration/Repair
Enzyme cascade
28. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure.
heparin
stress
Damage to cell membranes
Proteases
29. In order to produce a blood clot - thrombin cleaves/activates ____ and ____.
fibrinogen - factor XIII
glassy to rubbery
Allogeneic
Thrombin
30. The calculation of a polymer's molecular weight (weight average and number number average) is based upon values for ____ and ___.
Stable cells
Damage to cell membranes
Number of polymers - molecular weight of polymer
Hemocompatibility
31. ____ are enzymes responsible for protein degradation.
Proteases
Negative Feedback
standards of known properties
hypoxin - angiogenesis
32. Keloid scars forms because disfuntion of
labile cells
Macrophages
Collagenase
Extrusion
33. During granulation stage of proliferation - growth factors that produce this ____(answer)_____ that function in degrading fibrin and replacing it with collagen.
Polymers - cross linking of polymers
Proteases
Hemocompatibility
Mast - Collagen
34. Mast cells release this
Thermoplastics
heparin
Bioactive
mast cells
35. GPC separates molecules on the basis of size by their passage over a column packed with a porous matrix. ___ molecules pass through the column more quickly.
Large
in cytoplasm
Amide
Metals
36. The fatigue limit is value of applied stress below which a material will not fail no matter the number of ____ applied.
cycles
Extrusion
Enzyme cascade
Amide
37. Type of fiber drawing that controls details of a polymer by etching on a microscopic level; thus - controlling mechanical properties as well
Collagenase
Metals
micromachining
hypoxin - angiogenesis
38. Foreign body giants cells are produced by fusion of ___.
Calibration
Collagenase/Remodelling
Number of polymers - molecular weight of polymer
Macrophages
39. This type of feedback creates
negative feedback
Positive Feedback
Plastic
Calibration
40. Disfunction of _____ (cells) producing collagenase during the _____ phase of wound healing may form Keloid scars.
Collagenase/Remodelling
macrophages - proliferation
in cytoplasm
micromachining
41. No healing of damage neurons is the result of ____ cells that are not able to ____.
Endothelial cells
fibrinogen - factor XIII
Permanent - replicate
Polydesperity index
42. Is directed cell migration in response to a concentration gradient of soluble molecules.
heparin
Chemotaxis
standards of known properties
negative feedback
43. Which of polyermization (condensation/free radical) would you choose to obtain a polymer of high molecular weight?
Number of polymers - molecular weight of polymer
Mast - Collagen
Free Radical
angiogenesis
44. Essentially all metallic biomaterials are ____ - comprised of two or more metals. One of these metals is selected for its ability to support _____ - the formation of a stable oxide layer that resists further corrosion.
angiogenesis
heparin
neutrophils - macrophages
alloys - passivation
45. List two chemical characteristics of polymers:
Permanent cells
Intermolecular bonding - molecular weight
Compression molding
heparin
46. Thrombin activates several upstream factors.
Mast - Collagen
Free Radical
Collagenase
Positive Feedback
47. Two things needed in the end product of the creation of a scab
Polymers - cross linking of polymers
free radical
Allogeneic
Collagenase
48. You're working on a square polymeric implant of 5cm length and 2mm thick. You've been asked to suggest a precise way to fabricate it - what would you suggest?
Hemophilia
Compression molding
Free Radical
Thermoplastics
49. This cleaves into fibrinogen which creates fibrin (a sticky enzyme that allows blood to clot)
Thrombin
phagocytosis
Regeneration/Repair
neutrophils - macrophages
50. Deformation that cannot be recovered once the load is removed from the material is ____ deformation.
Protein Absorption
Negative Feedback
autologous
Plastic
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