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Test your basic knowledge |
Bio Engineering
Start Test
Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. This type of feedback creates
Plastic
in cytoplasm
negative feedback
Positive Feedback
2. Deformation that cannot be recovered once the load is removed from the material is ____ deformation.
Lower
Phagocytosis
Plastic
Metals
3. Thrombin activates several upstream factors.
photoactive polymers
Positive Feedback
Polymers - cross linking of polymers
Permanent - replicate
4. Cardiac bypass surgery in which a vein from a patient's leg is transplanted to the patient's heart is an example of the us of ____ tissue.
cross - linking
autologous
Thrombin
Amide
5. ____ describes the ability of a device to function appropriately in the presence of blood.
Hemocompatibility
Bioactive
Amide
Proteases
6. Enzymes (proteins) are not activated only when they are in contact with this type of cells
angiogenesis
Polymers - cross linking of polymers
Plastic
Endothelial cells
7. ____ are enzymes responsible for protein degradation.
Proteases
Heparin
cycles
Water
8. What type of materials are used for photolithography? (substrate is a silicon wafer - built up material is some _____ ____ )
Heparin
stress
Macrophages
photoactive polymers
9. Thrombin also activates protein C-- which deactivates earlier factors in the cascade is known as ___ ___.
Lower
Negative Feedback
stress
Thrombin
10. Cells that don't proliferate (neurons)
Permanent cells
cross - linking
Have to be in a clean room free of dust and biocontamination - expensive
angiogenesis
11. Vascular endothelial growth factor is produced in response to ___ and stimulates ___.
Thrombin
Bioactive
hypoxin - angiogenesis
Endothelial cells
12. Higher Molecular weight degrades slower than ____ MW
Stable cells
labile cells
Lower
Permanent cells
13. Cells that proliferate rapidly (fibroblasts)
labile cells
Plastic
mast cells
Metals
14. Damaged cells at the site of injury (mast cells) release ___ (glycosaminoglycan).
Collagenase
heparin
Phagocytosis
Proteases
15. Essentially all metallic biomaterials are ____ - comprised of two or more metals. One of these metals is selected for its ability to support _____ - the formation of a stable oxide layer that resists further corrosion.
Protein Absorption
alloys - passivation
scars
phagocytosis
16. The fibrous capsule surrounding a permanent implant is primarily composed of ___ cells and ____ (matrix).
Thrombin
negative feedback
Negative Feedback
Mast - Collagen
17. ____ is the process by which cells involved in inflammation internalize and destroy foreign material.
Phagocytosis
Extrusion
heparin
photoactive polymers
18. GPC separates molecules on the basis of size by their passage over a column packed with a porous matrix. ___ molecules pass through the column more quickly.
Large
cross - linking
Negative Feedback
Thrombin
19. High conductivity - isotropic - crystalline
micromachining
heparin
Metals
autologous
20. You're working on a square polymeric implant of 5cm length and 2mm thick. You've been asked to suggest a precise way to fabricate it - what would you suggest?
in cytoplasm
Water
Calibration
Compression molding
21. Classify the following polymers into appropriate families based on their bond structure i.e. the polymer is an example of poly ____.
cross - linking
Amide
Have to be in a clean room free of dust and biocontamination - expensive
alloys - passivation
22. Enzyme that really gets the polmerization going!
macrophages - proliferation
Lower
Water
Thrombin
23. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure.
stress
Mast - Collagen
Compression molding
Water - oxygen - metal
24. Addition polymerization is commonly initiated by ___ - atoms that have an unpaired electron.
alloys - passivation
free radical
Water
micromachining
25. ______ Molecular weight degrades slower than lower MW
Allogeneic
heparin
Higher
Mast - Collagen
26. Cell found in the lining of the blood vessels that release heparin and are a part of the negative feedback system.
mast cells
angiogenesis
in cytoplasm
cycles
27. Keloid scars forms because disfuntion of
Negative Feedback
in cytoplasm
heparin
Collagenase
28. Drawback of micromaching
Have to be in a clean room free of dust and biocontamination - expensive
autologous
Polymers - cross linking of polymers
Compression molding
29. Neutrophils remove bacteria/damaged cell debris from a wound site through the process of ___.
chemotaxis
phagocytosis
Collagenase/Remodelling
Mast - Collagen
30. Condition in which patients can literally bleed to death.
autologous
Hemophilia
Bioactive
chemotaxis
31. The two types of white blood cells:
Free Radical
fibrinogen - factor XIII
neutrophils - macrophages
Polymers - cross linking of polymers
32. The trigger for activation of enzymes (anything but endothelial cells!)
scars
Endothelial cells
low
binding
33. Where are the tissue factors found when they're inactivated
in cytoplasm
Have to be in a clean room free of dust and biocontamination - expensive
photoactive polymers
Regeneration/Repair
34. A condensation polymerization results with an ester bond between two reactants and this comes off as a result
labile cells
Chemotaxis
Allogeneic
Water
35. Type of fiber drawing that controls details of a polymer by etching on a microscopic level; thus - controlling mechanical properties as well
micromachining
Macrophages
Phagocytosis
standards of known properties
36. Which of polyermization (condensation/free radical) would you choose to obtain a polymer of high molecular weight?
Number of polymers - molecular weight of polymer
Free Radical
Polymers - cross linking of polymers
Higher
37. ____ binds to anti- thrombin III (thrombin inhibitor) and increases its potency 1000- fold.
neutrophils - macrophages
Mast - Collagen
Bioactive
Heparin
38. Collagen ____ is responsible for the gradual gain in mechanical properties of wounded tissue between roughly 4 and 52 weeks post- injury.
heparin
Regeneration/Repair
Polydesperity index
cross - linking
39. Resulting from the build up of too much collagen at the surface of injury during the granulation tissue stage of proliferation
Hemophilia
scars
fibrinogen - factor XIII
Protein Absorption
40. What types of wound healing results from injury with inflammation?
Hemophilia
Polymers - cross linking of polymers
Regeneration/Repair
Number of polymers - molecular weight of polymer
41. Cells that proliferate slowly over time (aka liver)
cycles
Metals
Stable cells
Macrophages
42. The fatigue limit is value of applied stress below which a material will not fail no matter the number of ____ applied.
Proteases
micromachining
Collagenase/Remodelling
cycles
43. ____- are polymers that can be repeatedly softened by heating and hardened by cooling.
Collagenase
Plastic
Negative Feedback
Thermoplastics
44. The process of calibration establishes a quantitative relationship between ____ __ ___ _____ and the direct output of the intstrument (for example time/volume in GPC).
glassy to rubbery
standards of known properties
photoactive polymers
cross - linking
45. ____ grafts are derived from the other humans.
cross - linking
Allogeneic
binding
Water - oxygen - metal
46. A ____ implant is designed to elicit specific - intended to host responses.
micromachining
Polymers - cross linking of polymers
cycles
Bioactive
47. The formation of rust due to corrosion in the body is due to the reaction between these 3 things ____ - ____ - and ____ .
Water - oxygen - metal
Heparin
Enzyme cascade
Metals
48. Foreign body giants cells are produced by fusion of ___.
Negative Feedback
Proteases
Macrophages
Enzyme cascade
49. A molecular pathway in which the product of each reaction catalyzes the subsequent reaction.
Enzyme cascade
Hemocompatibility
Metals
Stress
50. In order to produce a blood clot - thrombin cleaves/activates ____ and ____.
Large
macrophages - proliferation
fibrinogen - factor XIII
Calibration