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Bio Engineering
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Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
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study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Thrombin also activates protein C-- which deactivates earlier factors in the cascade is known as ___ ___.
Negative Feedback
Stress
phagocytosis
Endothelial cells
2. Process of producing new blood vessels due to a lack on oxygen and thus inducing VEGF.
angiogenesis
autologous
chemotaxis
alloys - passivation
3. In order to produce a blood clot - thrombin cleaves/activates ____ and ____.
free radical
Extrusion
phagocytosis
fibrinogen - factor XIII
4. Neutrophils remove bacteria/damaged cell debris from a wound site through the process of ___.
Hemocompatibility
Collagenase/Remodelling
Number of polymers - molecular weight of polymer
phagocytosis
5. Thrombin activates several upstream factors.
Positive Feedback
Compression molding
scars
macrophages - proliferation
6. You're working on a square polymeric implant of 5cm length and 2mm thick. You've been asked to suggest a precise way to fabricate it - what would you suggest?
binding
Compression molding
Regeneration/Repair
Large
7. ____ is the process by which cells involved in inflammation internalize and destroy foreign material.
Hemophilia
Large
angiogenesis
Phagocytosis
8. Enzymes (proteins) are not activated only when they are in contact with this type of cells
Permanent - replicate
Endothelial cells
free radical
hypoxin - angiogenesis
9. This type of feedback creates
Enzyme cascade
Thrombin
Amide
negative feedback
10. Vascular endothelial growth factor is produced in response to ___ and stimulates ___.
Thrombin
Proteases
Amide
hypoxin - angiogenesis
11. Enzyme that really gets the polmerization going!
Have to be in a clean room free of dust and biocontamination - expensive
Negative Feedback
Thrombin
Macrophages
12. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure
Stress
Free Radical
low
Damage to cell membranes
13. Foreign body giants cells are produced by fusion of ___.
Macrophages
Endothelial cells
glassy to rubbery
in cytoplasm
14. Higher Molecular weight degrades slower than ____ MW
macrophages - proliferation
Lower
Heparin
low
15. Addition polymerization is commonly initiated by ___ - atoms that have an unpaired electron.
free radical
Metals
stress
cross - linking
16. The trigger for activation of enzymes (anything but endothelial cells!)
Metals
binding
Phagocytosis
Plasticizers
17. During granulation stage of proliferation - growth factors that produce this ____(answer)_____ that function in degrading fibrin and replacing it with collagen.
Metals
Proteases
Large
Damage to cell membranes
18. The calculation of a polymer's molecular weight (weight average and number number average) is based upon values for ____ and ___.
stress
cycles
Water - oxygen - metal
Number of polymers - molecular weight of polymer
19. _____ establishes a quantitative relationship between measured output values from an instrument and known standards of what is being measured.
Calibration
Extrusion
Compression molding
Lower
20. The fibrous capsule surrounding a permanent implant is primarily composed of ___ cells and ____ (matrix).
free radical
Heparin
Mast - Collagen
stress
21. GPC separates molecules on the basis of size by their passage over a column packed with a porous matrix. ___ molecules pass through the column more quickly.
chemotaxis
Large
low
Water - oxygen - metal
22. Two things needed in the end product of the creation of a scab
Phagocytosis
Allogeneic
Polymers - cross linking of polymers
Protein Absorption
23. What types of wound healing results from injury with inflammation?
Stress
Regeneration/Repair
Allogeneic
Polymers - cross linking of polymers
24. Damaged cells at the site of injury (mast cells) release ___ (glycosaminoglycan).
Proteases
low
Collagenase
heparin
25. The two types of white blood cells:
negative feedback
binding
neutrophils - macrophages
labile cells
26. Disfunction of _____ (cells) producing collagenase during the _____ phase of wound healing may form Keloid scars.
hypoxin - angiogenesis
macrophages - proliferation
Damage to cell membranes
Hemophilia
27. Drawback of micromaching
mast cells
low
Have to be in a clean room free of dust and biocontamination - expensive
Enzyme cascade
28. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure.
Large
phagocytosis
Enzyme cascade
stress
29. List two chemical characteristics of polymers:
glassy to rubbery
Regeneration/Repair
Negative Feedback
Intermolecular bonding - molecular weight
30. Deformation that cannot be recovered once the load is removed from the material is ____ deformation.
Plastic
Phagocytosis
Proteases
mast cells
31. Where are the tissue factors found when they're inactivated
Have to be in a clean room free of dust and biocontamination - expensive
in cytoplasm
macrophages - proliferation
Intermolecular bonding - molecular weight
32. Is directed cell migration in response to a concentration gradient of soluble molecules.
Chemotaxis
Polymers - cross linking of polymers
Permanent - replicate
Allogeneic
33. The formation of rust due to corrosion in the body is due to the reaction between these 3 things ____ - ____ - and ____ .
Water - oxygen - metal
phagocytosis
scars
Extrusion
34. Activates tissue factors aka endothelial damage
Higher
macrophages - proliferation
Damage to cell membranes
Lower
35. Classify the following polymers into appropriate families based on their bond structure i.e. the polymer is an example of poly ____.
Number of polymers - molecular weight of polymer
Amide
Phagocytosis
Thrombin
36. Essentially all metallic biomaterials are ____ - comprised of two or more metals. One of these metals is selected for its ability to support _____ - the formation of a stable oxide layer that resists further corrosion.
angiogenesis
Polydesperity index
alloys - passivation
Thrombin
37. A molecular pathway in which the product of each reaction catalyzes the subsequent reaction.
Enzyme cascade
Phagocytosis
Intermolecular bonding - molecular weight
Damage to cell membranes
38. Cell found in the lining of the blood vessels that release heparin and are a part of the negative feedback system.
mast cells
Metals
Thrombin
Negative Feedback
39. Are polymer additives used to lower glass transition temperature temperature.
Negative Feedback
Permanent cells
macrophages - proliferation
Plasticizers
40. No healing of damage neurons is the result of ____ cells that are not able to ____.
Regeneration/Repair
Mast - Collagen
Permanent - replicate
Hemocompatibility
41. The glass transition temperature of a poymer at which a polymer transforms from a ____ state to a ___ state.
Permanent - replicate
glassy to rubbery
Thermoplastics
Thrombin
42. ____ describes the ability of a device to function appropriately in the presence of blood.
Hemocompatibility
micromachining
glassy to rubbery
photoactive polymers
43. Keloid scars form due to disfunction of ____.
mast cells
Collagenase/Remodelling
Have to be in a clean room free of dust and biocontamination - expensive
Collagenase
44. The fatigue limit is value of applied stress below which a material will not fail no matter the number of ____ applied.
cycles
standards of known properties
Phagocytosis
Hemophilia
45. Resulting from the build up of too much collagen at the surface of injury during the granulation tissue stage of proliferation
Lower
stress
scars
cycles
46. Cells that don't proliferate (neurons)
Extrusion
Permanent - replicate
Collagenase
Permanent cells
47. High conductivity - isotropic - crystalline
Permanent - replicate
Metals
Hemocompatibility
in cytoplasm
48. ____ binds to anti- thrombin III (thrombin inhibitor) and increases its potency 1000- fold.
Permanent cells
Heparin
Enzyme cascade
Thrombin
49. Condition in which patients can literally bleed to death.
Plasticizers
Hemophilia
Heparin
Regeneration/Repair
50. Cells that proliferate rapidly (fibroblasts)
Water
labile cells
Endothelial cells
mast cells
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