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Test your basic knowledge |
Bio Engineering
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Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Activates tissue factors aka endothelial damage
hypoxin - angiogenesis
Water
Damage to cell membranes
Number of polymers - molecular weight of polymer
2. Keloid scars form due to disfunction of ____.
Endothelial cells
Polymers - cross linking of polymers
Collagenase/Remodelling
Damage to cell membranes
3. Condition in which patients can literally bleed to death.
Hemophilia
hypoxin - angiogenesis
Water
Positive Feedback
4. Essentially all metallic biomaterials are ____ - comprised of two or more metals. One of these metals is selected for its ability to support _____ - the formation of a stable oxide layer that resists further corrosion.
Regeneration/Repair
alloys - passivation
Thrombin
Proteases
5. Enzymes (proteins) are not activated only when they are in contact with this type of cells
cross - linking
Endothelial cells
standards of known properties
Proteases
6. ____ binds to anti- thrombin III (thrombin inhibitor) and increases its potency 1000- fold.
Heparin
Collagenase
stress
alloys - passivation
7. Cells that proliferate slowly over time (aka liver)
Stable cells
neutrophils - macrophages
Damage to cell membranes
macrophages - proliferation
8. Collagen ____ is responsible for the gradual gain in mechanical properties of wounded tissue between roughly 4 and 52 weeks post- injury.
cross - linking
Macrophages
Hemocompatibility
Permanent - replicate
9. The fibrous capsule surrounding a permanent implant is primarily composed of ___ cells and ____ (matrix).
standards of known properties
scars
fibrinogen - factor XIII
Mast - Collagen
10. Keloid scars forms because disfuntion of
photoactive polymers
heparin
Collagenase
standards of known properties
11. ______ Molecular weight degrades slower than lower MW
Higher
Water - oxygen - metal
Number of polymers - molecular weight of polymer
chemotaxis
12. Two things needed in the end product of the creation of a scab
autologous
Lower
Polymers - cross linking of polymers
Polydesperity index
13. The formation of rust due to corrosion in the body is due to the reaction between these 3 things ____ - ____ - and ____ .
hypoxin - angiogenesis
Water - oxygen - metal
photoactive polymers
Positive Feedback
14. What type of materials are used for photolithography? (substrate is a silicon wafer - built up material is some _____ ____ )
photoactive polymers
macrophages - proliferation
standards of known properties
Endothelial cells
15. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure
Allogeneic
Stress
alloys - passivation
Amide
16. List two chemical characteristics of polymers:
Metals
Permanent - replicate
mast cells
Intermolecular bonding - molecular weight
17. ____ grafts are derived from the other humans.
Allogeneic
scars
angiogenesis
Collagenase
18. Drawback of micromaching
Plastic
fibrinogen - factor XIII
Heparin
Have to be in a clean room free of dust and biocontamination - expensive
19. Classify the following polymers into appropriate families based on their bond structure i.e. the polymer is an example of poly ____.
Bioactive
photoactive polymers
Amide
Number of polymers - molecular weight of polymer
20. Rather than randomly moving - moves in a directed cell migration manner for specific functions.
Compression molding
chemotaxis
fibrinogen - factor XIII
standards of known properties
21. Damaged cells at the site of injury (mast cells) release ___ (glycosaminoglycan).
Thrombin
scars
heparin
autologous
22. This cleaves into fibrinogen which creates fibrin (a sticky enzyme that allows blood to clot)
heparin
Allogeneic
Calibration
Thrombin
23. Process that makes long fibers (fiber drawing) by forcing a fluid through an oriface.
Plasticizers
Polydesperity index
Hemocompatibility
Extrusion
24. Cells that proliferate rapidly (fibroblasts)
Mast - Collagen
Water
Metals
labile cells
25. ____ are enzymes responsible for protein degradation.
Extrusion
Proteases
neutrophils - macrophages
macrophages - proliferation
26. A condensation polymerization results with an ester bond between two reactants and this comes off as a result
Permanent cells
hypoxin - angiogenesis
Have to be in a clean room free of dust and biocontamination - expensive
Water
27. The process of calibration establishes a quantitative relationship between ____ __ ___ _____ and the direct output of the intstrument (for example time/volume in GPC).
free radical
negative feedback
standards of known properties
scars
28. Addition polymerization is commonly initiated by ___ - atoms that have an unpaired electron.
Permanent cells
Plasticizers
angiogenesis
free radical
29. The glass transition temperature of a poymer at which a polymer transforms from a ____ state to a ___ state.
Protein Absorption
Proteases
Calibration
glassy to rubbery
30. The calculation of a polymer's molecular weight (weight average and number number average) is based upon values for ____ and ___.
Number of polymers - molecular weight of polymer
Calibration
Plastic
stress
31. The two types of white blood cells:
neutrophils - macrophages
Negative Feedback
Plasticizers
Lower
32. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure.
neutrophils - macrophages
stress
low
in cytoplasm
33. High conductivity - isotropic - crystalline
Polymers - cross linking of polymers
Metals
Lower
Stress
34. Enzyme that really gets the polmerization going!
Thrombin
Collagenase/Remodelling
Negative Feedback
chemotaxis
35. Vascular endothelial growth factor is produced in response to ___ and stimulates ___.
Intermolecular bonding - molecular weight
hypoxin - angiogenesis
Allogeneic
Hemophilia
36. Disfunction of _____ (cells) producing collagenase during the _____ phase of wound healing may form Keloid scars.
Thrombin
fibrinogen - factor XIII
macrophages - proliferation
Calibration
37. The fatigue limit is value of applied stress below which a material will not fail no matter the number of ____ applied.
Mast - Collagen
cycles
autologous
Regeneration/Repair
38. ____- are polymers that can be repeatedly softened by heating and hardened by cooling.
Thermoplastics
Protein Absorption
Plastic
Have to be in a clean room free of dust and biocontamination - expensive
39. Resulting from the build up of too much collagen at the surface of injury during the granulation tissue stage of proliferation
stress
scars
Permanent cells
Phagocytosis
40. Cells that don't proliferate (neurons)
Proteases
Permanent cells
Mast - Collagen
Allogeneic
41. ____ describes the ability of a device to function appropriately in the presence of blood.
Amide
Hemocompatibility
Water - oxygen - metal
Heparin
42. Polyethylene oxide grafting to biomaterials was developed to prevent coagulation by interfering with/preventing ___ ___.
Number of polymers - molecular weight of polymer
macrophages - proliferation
Large
Protein Absorption
43. GPC separates molecules on the basis of size by their passage over a column packed with a porous matrix. ___ molecules pass through the column more quickly.
Number of polymers - molecular weight of polymer
Collagenase
phagocytosis
Large
44. What types of wound healing results from injury with inflammation?
Macrophages
heparin
Regeneration/Repair
hypoxin - angiogenesis
45. This type of feedback creates
angiogenesis
Protein Absorption
negative feedback
Mast - Collagen
46. No healing of damage neurons is the result of ____ cells that are not able to ____.
Permanent cells
labile cells
Permanent - replicate
Damage to cell membranes
47. Thrombin also activates protein C-- which deactivates earlier factors in the cascade is known as ___ ___.
Negative Feedback
Number of polymers - molecular weight of polymer
Calibration
cross - linking
48. Process of producing new blood vessels due to a lack on oxygen and thus inducing VEGF.
phagocytosis
angiogenesis
Hemocompatibility
Collagenase
49. The trigger for activation of enzymes (anything but endothelial cells!)
Higher
Intermolecular bonding - molecular weight
binding
Damage to cell membranes
50. Cardiac bypass surgery in which a vein from a patient's leg is transplanted to the patient's heart is an example of the us of ____ tissue.
autologous
cross - linking
Water
binding
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