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Test your basic knowledge |
Bio Engineering
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Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
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study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. The formation of rust due to corrosion in the body is due to the reaction between these 3 things ____ - ____ - and ____ .
Water - oxygen - metal
Thermoplastics
Bioactive
Free Radical
2. Thrombin activates several upstream factors.
cycles
Enzyme cascade
Thrombin
Positive Feedback
3. ____- are polymers that can be repeatedly softened by heating and hardened by cooling.
Thermoplastics
Phagocytosis
Extrusion
labile cells
4. Thrombin also activates protein C-- which deactivates earlier factors in the cascade is known as ___ ___.
free radical
Lower
Negative Feedback
Stress
5. This cleaves into fibrinogen which creates fibrin (a sticky enzyme that allows blood to clot)
Water
Thrombin
Chemotaxis
macrophages - proliferation
6. The two types of white blood cells:
Allogeneic
neutrophils - macrophages
glassy to rubbery
Endothelial cells
7. Rather than randomly moving - moves in a directed cell migration manner for specific functions.
Negative Feedback
Thrombin
Free Radical
chemotaxis
8. Are polymer additives used to lower glass transition temperature temperature.
Negative Feedback
Plasticizers
Bioactive
photoactive polymers
9. Condition in which patients can literally bleed to death.
Negative Feedback
negative feedback
Hemophilia
Proteases
10. ____ binds to anti- thrombin III (thrombin inhibitor) and increases its potency 1000- fold.
binding
Heparin
alloys - passivation
free radical
11. No healing of damage neurons is the result of ____ cells that are not able to ____.
glassy to rubbery
Damage to cell membranes
Permanent - replicate
Metals
12. Resulting from the build up of too much collagen at the surface of injury during the granulation tissue stage of proliferation
Chemotaxis
scars
Enzyme cascade
low
13. During granulation stage of proliferation - growth factors that produce this ____(answer)_____ that function in degrading fibrin and replacing it with collagen.
Stable cells
free radical
Proteases
Compression molding
14. GPC separates molecules on the basis of size by their passage over a column packed with a porous matrix. ___ molecules pass through the column more quickly.
glassy to rubbery
angiogenesis
Have to be in a clean room free of dust and biocontamination - expensive
Large
15. A ____ implant is designed to elicit specific - intended to host responses.
Proteases
Bioactive
Lower
Stress
16. ____ is a measurement that characterizes the breadth of the distribution of a polymer's molecular weight.
Polydesperity index
Thermoplastics
binding
Calibration
17. Process of producing new blood vessels due to a lack on oxygen and thus inducing VEGF.
angiogenesis
Hemophilia
low
Stress
18. Foreign body giants cells are produced by fusion of ___.
alloys - passivation
Macrophages
Heparin
Intermolecular bonding - molecular weight
19. Keloid scars forms because disfuntion of
photoactive polymers
heparin
Large
Collagenase
20. Activates tissue factors aka endothelial damage
stress
Damage to cell membranes
Free Radical
Phagocytosis
21. The trigger for activation of enzymes (anything but endothelial cells!)
chemotaxis
binding
Endothelial cells
Regeneration/Repair
22. Vascular endothelial growth factor is produced in response to ___ and stimulates ___.
Extrusion
Protein Absorption
cycles
hypoxin - angiogenesis
23. A condensation polymerization results with an ester bond between two reactants and this comes off as a result
glassy to rubbery
micromachining
Water
Thrombin
24. Essentially all metallic biomaterials are ____ - comprised of two or more metals. One of these metals is selected for its ability to support _____ - the formation of a stable oxide layer that resists further corrosion.
Polydesperity index
Amide
macrophages - proliferation
alloys - passivation
25. Drawback of micromaching
Polydesperity index
Have to be in a clean room free of dust and biocontamination - expensive
cycles
angiogenesis
26. Neutrophils remove bacteria/damaged cell debris from a wound site through the process of ___.
Heparin
phagocytosis
photoactive polymers
free radical
27. Mast cells release this
Hemophilia
hypoxin - angiogenesis
Stress
heparin
28. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure.
heparin
Permanent - replicate
stress
Intermolecular bonding - molecular weight
29. The process of calibration establishes a quantitative relationship between ____ __ ___ _____ and the direct output of the intstrument (for example time/volume in GPC).
Heparin
Damage to cell membranes
standards of known properties
Stress
30. A molecular pathway in which the product of each reaction catalyzes the subsequent reaction.
Collagenase
Positive Feedback
Enzyme cascade
Chemotaxis
31. Two things needed in the end product of the creation of a scab
Negative Feedback
Hemophilia
neutrophils - macrophages
Polymers - cross linking of polymers
32. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure
autologous
Collagenase/Remodelling
Stress
macrophages - proliferation
33. ____ grafts are derived from the other humans.
hypoxin - angiogenesis
fibrinogen - factor XIII
Allogeneic
Plastic
34. Which of polyermization (condensation/free radical) would you choose to obtain a polymer of high molecular weight?
Free Radical
Have to be in a clean room free of dust and biocontamination - expensive
fibrinogen - factor XIII
Large
35. Enzymes (proteins) are not activated only when they are in contact with this type of cells
Endothelial cells
binding
Free Radical
Phagocytosis
36. The fibrous capsule surrounding a permanent implant is primarily composed of ___ cells and ____ (matrix).
hypoxin - angiogenesis
Higher
Mast - Collagen
Macrophages
37. Deformation that cannot be recovered once the load is removed from the material is ____ deformation.
neutrophils - macrophages
Thrombin
Thrombin
Plastic
38. Damaged cells at the site of injury (mast cells) release ___ (glycosaminoglycan).
Enzyme cascade
cycles
free radical
heparin
39. ____ are enzymes responsible for protein degradation.
Intermolecular bonding - molecular weight
photoactive polymers
Compression molding
Proteases
40. Cell found in the lining of the blood vessels that release heparin and are a part of the negative feedback system.
Water
Collagenase/Remodelling
scars
mast cells
41. Addition polymerization is commonly initiated by ___ - atoms that have an unpaired electron.
Large
Have to be in a clean room free of dust and biocontamination - expensive
free radical
Chemotaxis
42. ____ describes the ability of a device to function appropriately in the presence of blood.
Free Radical
Water - oxygen - metal
Intermolecular bonding - molecular weight
Hemocompatibility
43. This type of feedback creates
Collagenase
Thermoplastics
negative feedback
Number of polymers - molecular weight of polymer
44. Collagen ____ is responsible for the gradual gain in mechanical properties of wounded tissue between roughly 4 and 52 weeks post- injury.
Water
cross - linking
Heparin
Stress
45. Classify the following polymers into appropriate families based on their bond structure i.e. the polymer is an example of poly ____.
Have to be in a clean room free of dust and biocontamination - expensive
Plastic
Amide
Stable cells
46. Where are the tissue factors found when they're inactivated
Proteases
Positive Feedback
in cytoplasm
mast cells
47. Polyethylene oxide grafting to biomaterials was developed to prevent coagulation by interfering with/preventing ___ ___.
Stable cells
Protein Absorption
Plasticizers
Permanent - replicate
48. Enzyme that really gets the polmerization going!
free radical
Thrombin
Chemotaxis
Stable cells
49. The calculation of a polymer's molecular weight (weight average and number number average) is based upon values for ____ and ___.
Plastic
Number of polymers - molecular weight of polymer
macrophages - proliferation
Allogeneic
50. Relative to free radical polymerization - condensation polymerization generally produces polymer of relatively ____ molecular weight.
low
fibrinogen - factor XIII
Stress
neutrophils - macrophages
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