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Test your basic knowledge |
Bio Engineering
Start Test
Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Collagen ____ is responsible for the gradual gain in mechanical properties of wounded tissue between roughly 4 and 52 weeks post- injury.
cross - linking
Hemophilia
Regeneration/Repair
low
2. During granulation stage of proliferation - growth factors that produce this ____(answer)_____ that function in degrading fibrin and replacing it with collagen.
Proteases
Extrusion
Hemocompatibility
Hemophilia
3. Damaged cells at the site of injury (mast cells) release ___ (glycosaminoglycan).
Amide
heparin
negative feedback
standards of known properties
4. Cells that don't proliferate (neurons)
Number of polymers - molecular weight of polymer
Proteases
Calibration
Permanent cells
5. Foreign body giants cells are produced by fusion of ___.
Macrophages
cycles
Enzyme cascade
Metals
6. Keloid scars forms because disfuntion of
Collagenase
Free Radical
Damage to cell membranes
Negative Feedback
7. Polyethylene oxide grafting to biomaterials was developed to prevent coagulation by interfering with/preventing ___ ___.
Protein Absorption
phagocytosis
Stable cells
Large
8. You're working on a square polymeric implant of 5cm length and 2mm thick. You've been asked to suggest a precise way to fabricate it - what would you suggest?
Free Radical
binding
Compression molding
Hemophilia
9. Neutrophils remove bacteria/damaged cell debris from a wound site through the process of ___.
Higher
Thrombin
phagocytosis
Large
10. Process that makes long fibers (fiber drawing) by forcing a fluid through an oriface.
Allogeneic
Extrusion
Mast - Collagen
labile cells
11. List two chemical characteristics of polymers:
Hemocompatibility
Enzyme cascade
Intermolecular bonding - molecular weight
labile cells
12. Cardiac bypass surgery in which a vein from a patient's leg is transplanted to the patient's heart is an example of the us of ____ tissue.
Thrombin
autologous
Mast - Collagen
Water - oxygen - metal
13. Process of producing new blood vessels due to a lack on oxygen and thus inducing VEGF.
Amide
binding
in cytoplasm
angiogenesis
14. Resulting from the build up of too much collagen at the surface of injury during the granulation tissue stage of proliferation
scars
Thrombin
glassy to rubbery
Macrophages
15. Essentially all metallic biomaterials are ____ - comprised of two or more metals. One of these metals is selected for its ability to support _____ - the formation of a stable oxide layer that resists further corrosion.
Calibration
alloys - passivation
Higher
Heparin
16. This type of feedback creates
Free Radical
scars
Polydesperity index
negative feedback
17. ____ describes the ability of a device to function appropriately in the presence of blood.
Hemocompatibility
Water
autologous
Regeneration/Repair
18. Mast cells release this
Bioactive
heparin
Allogeneic
micromachining
19. Activates tissue factors aka endothelial damage
Collagenase
Damage to cell membranes
Stable cells
Macrophages
20. Two things needed in the end product of the creation of a scab
angiogenesis
Endothelial cells
Hemophilia
Polymers - cross linking of polymers
21. Where are the tissue factors found when they're inactivated
chemotaxis
in cytoplasm
Number of polymers - molecular weight of polymer
fibrinogen - factor XIII
22. This cleaves into fibrinogen which creates fibrin (a sticky enzyme that allows blood to clot)
Have to be in a clean room free of dust and biocontamination - expensive
Permanent - replicate
Protein Absorption
Thrombin
23. In order to produce a blood clot - thrombin cleaves/activates ____ and ____.
Permanent - replicate
Allogeneic
Polydesperity index
fibrinogen - factor XIII
24. A molecular pathway in which the product of each reaction catalyzes the subsequent reaction.
Negative Feedback
Mast - Collagen
standards of known properties
Enzyme cascade
25. A condensation polymerization results with an ester bond between two reactants and this comes off as a result
Compression molding
angiogenesis
Water
Allogeneic
26. Cell found in the lining of the blood vessels that release heparin and are a part of the negative feedback system.
chemotaxis
mast cells
Amide
labile cells
27. Drawback of micromaching
Collagenase/Remodelling
Have to be in a clean room free of dust and biocontamination - expensive
low
Proteases
28. The fibrous capsule surrounding a permanent implant is primarily composed of ___ cells and ____ (matrix).
free radical
negative feedback
Negative Feedback
Mast - Collagen
29. ____ binds to anti- thrombin III (thrombin inhibitor) and increases its potency 1000- fold.
Polymers - cross linking of polymers
Macrophages
stress
Heparin
30. The process of calibration establishes a quantitative relationship between ____ __ ___ _____ and the direct output of the intstrument (for example time/volume in GPC).
Mast - Collagen
standards of known properties
Plastic
heparin
31. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure
Calibration
Stable cells
Stress
Permanent - replicate
32. Rather than randomly moving - moves in a directed cell migration manner for specific functions.
Mast - Collagen
chemotaxis
angiogenesis
Thermoplastics
33. Deformation that cannot be recovered once the load is removed from the material is ____ deformation.
Amide
Thrombin
Plastic
alloys - passivation
34. Addition polymerization is commonly initiated by ___ - atoms that have an unpaired electron.
free radical
chemotaxis
micromachining
Lower
35. Keloid scars form due to disfunction of ____.
Collagenase/Remodelling
Metals
Number of polymers - molecular weight of polymer
Plastic
36. ______ Molecular weight degrades slower than lower MW
Higher
autologous
Water
Polymers - cross linking of polymers
37. High conductivity - isotropic - crystalline
Higher
Hemocompatibility
Metals
alloys - passivation
38. The formation of rust due to corrosion in the body is due to the reaction between these 3 things ____ - ____ - and ____ .
Damage to cell membranes
Water - oxygen - metal
Protein Absorption
Proteases
39. The trigger for activation of enzymes (anything but endothelial cells!)
binding
heparin
phagocytosis
stress
40. ____ is the process by which cells involved in inflammation internalize and destroy foreign material.
fibrinogen - factor XIII
Calibration
Permanent - replicate
Phagocytosis
41. Cells that proliferate rapidly (fibroblasts)
alloys - passivation
labile cells
Collagenase
Water - oxygen - metal
42. ____ are enzymes responsible for protein degradation.
Proteases
Regeneration/Repair
Plastic
photoactive polymers
43. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure.
Plasticizers
stress
Polydesperity index
neutrophils - macrophages
44. What type of materials are used for photolithography? (substrate is a silicon wafer - built up material is some _____ ____ )
Endothelial cells
photoactive polymers
Damage to cell membranes
Polydesperity index
45. Cells that proliferate slowly over time (aka liver)
Extrusion
Bioactive
Stable cells
Protein Absorption
46. A ____ implant is designed to elicit specific - intended to host responses.
Large
Macrophages
Amide
Bioactive
47. ____ is a measurement that characterizes the breadth of the distribution of a polymer's molecular weight.
standards of known properties
cycles
Plasticizers
Polydesperity index
48. Is directed cell migration in response to a concentration gradient of soluble molecules.
Positive Feedback
photoactive polymers
Phagocytosis
Chemotaxis
49. Are polymer additives used to lower glass transition temperature temperature.
Compression molding
Amide
Calibration
Plasticizers
50. ____ grafts are derived from the other humans.
Protein Absorption
labile cells
mast cells
Allogeneic