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Test your basic knowledge |
Bio Engineering
Start Test
Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Cells that proliferate rapidly (fibroblasts)
labile cells
negative feedback
Water - oxygen - metal
alloys - passivation
2. ____ is a measurement that characterizes the breadth of the distribution of a polymer's molecular weight.
cross - linking
Intermolecular bonding - molecular weight
Polydesperity index
phagocytosis
3. Two things needed in the end product of the creation of a scab
heparin
Chemotaxis
Polymers - cross linking of polymers
Water - oxygen - metal
4. Vascular endothelial growth factor is produced in response to ___ and stimulates ___.
macrophages - proliferation
hypoxin - angiogenesis
Permanent - replicate
Intermolecular bonding - molecular weight
5. Polyethylene oxide grafting to biomaterials was developed to prevent coagulation by interfering with/preventing ___ ___.
low
Heparin
Protein Absorption
heparin
6. Process that makes long fibers (fiber drawing) by forcing a fluid through an oriface.
Chemotaxis
Stable cells
Plasticizers
Extrusion
7. Foreign body giants cells are produced by fusion of ___.
standards of known properties
angiogenesis
cross - linking
Macrophages
8. Classify the following polymers into appropriate families based on their bond structure i.e. the polymer is an example of poly ____.
scars
Amide
Hemophilia
mast cells
9. Damaged cells at the site of injury (mast cells) release ___ (glycosaminoglycan).
standards of known properties
Calibration
heparin
Collagenase/Remodelling
10. Enzymes (proteins) are not activated only when they are in contact with this type of cells
binding
hypoxin - angiogenesis
Endothelial cells
low
11. ____ binds to anti- thrombin III (thrombin inhibitor) and increases its potency 1000- fold.
Heparin
Macrophages
Number of polymers - molecular weight of polymer
Polymers - cross linking of polymers
12. Drawback of micromaching
Have to be in a clean room free of dust and biocontamination - expensive
Polydesperity index
Thrombin
chemotaxis
13. Condition in which patients can literally bleed to death.
Thrombin
Hemophilia
standards of known properties
Thermoplastics
14. Thrombin also activates protein C-- which deactivates earlier factors in the cascade is known as ___ ___.
in cytoplasm
Polymers - cross linking of polymers
standards of known properties
Negative Feedback
15. Activates tissue factors aka endothelial damage
Thrombin
Bioactive
Damage to cell membranes
Amide
16. ____ is the process by which cells involved in inflammation internalize and destroy foreign material.
alloys - passivation
Thermoplastics
Phagocytosis
fibrinogen - factor XIII
17. Is directed cell migration in response to a concentration gradient of soluble molecules.
Proteases
phagocytosis
Amide
Chemotaxis
18. A ____ implant is designed to elicit specific - intended to host responses.
negative feedback
Bioactive
Protein Absorption
binding
19. Essentially all metallic biomaterials are ____ - comprised of two or more metals. One of these metals is selected for its ability to support _____ - the formation of a stable oxide layer that resists further corrosion.
Metals
Thermoplastics
alloys - passivation
Collagenase/Remodelling
20. The glass transition temperature of a poymer at which a polymer transforms from a ____ state to a ___ state.
Macrophages
Free Radical
heparin
glassy to rubbery
21. Thrombin activates several upstream factors.
in cytoplasm
Positive Feedback
Macrophages
Proteases
22. Cells that don't proliferate (neurons)
Free Radical
free radical
Hemocompatibility
Permanent cells
23. The trigger for activation of enzymes (anything but endothelial cells!)
Number of polymers - molecular weight of polymer
Chemotaxis
binding
Stable cells
24. Cells that proliferate slowly over time (aka liver)
Bioactive
negative feedback
Stable cells
Metals
25. GPC separates molecules on the basis of size by their passage over a column packed with a porous matrix. ___ molecules pass through the column more quickly.
macrophages - proliferation
standards of known properties
Proteases
Large
26. During granulation stage of proliferation - growth factors that produce this ____(answer)_____ that function in degrading fibrin and replacing it with collagen.
Phagocytosis
Calibration
scars
Proteases
27. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure.
free radical
macrophages - proliferation
Allogeneic
stress
28. The fatigue limit is value of applied stress below which a material will not fail no matter the number of ____ applied.
cycles
Damage to cell membranes
standards of known properties
Number of polymers - molecular weight of polymer
29. The process of calibration establishes a quantitative relationship between ____ __ ___ _____ and the direct output of the intstrument (for example time/volume in GPC).
Calibration
standards of known properties
Enzyme cascade
Water - oxygen - metal
30. High conductivity - isotropic - crystalline
Metals
Hemocompatibility
Plastic
Polymers - cross linking of polymers
31. Which of polyermization (condensation/free radical) would you choose to obtain a polymer of high molecular weight?
Plastic
Free Radical
Stress
Enzyme cascade
32. Disfunction of _____ (cells) producing collagenase during the _____ phase of wound healing may form Keloid scars.
macrophages - proliferation
Bioactive
fibrinogen - factor XIII
Permanent - replicate
33. ____ are enzymes responsible for protein degradation.
Enzyme cascade
Thermoplastics
Proteases
Permanent cells
34. What types of wound healing results from injury with inflammation?
Amide
hypoxin - angiogenesis
Macrophages
Regeneration/Repair
35. The two types of white blood cells:
neutrophils - macrophages
heparin
stress
labile cells
36. Cell found in the lining of the blood vessels that release heparin and are a part of the negative feedback system.
mast cells
binding
Regeneration/Repair
Polydesperity index
37. The fibrous capsule surrounding a permanent implant is primarily composed of ___ cells and ____ (matrix).
Mast - Collagen
chemotaxis
Polymers - cross linking of polymers
cycles
38. ____ grafts are derived from the other humans.
Allogeneic
Proteases
Permanent cells
Metals
39. You're working on a square polymeric implant of 5cm length and 2mm thick. You've been asked to suggest a precise way to fabricate it - what would you suggest?
Compression molding
heparin
Extrusion
Proteases
40. Higher Molecular weight degrades slower than ____ MW
Bioactive
Permanent - replicate
free radical
Lower
41. Are polymer additives used to lower glass transition temperature temperature.
autologous
Plasticizers
Allogeneic
Permanent - replicate
42. List two chemical characteristics of polymers:
Intermolecular bonding - molecular weight
Protein Absorption
Heparin
Mast - Collagen
43. Neutrophils remove bacteria/damaged cell debris from a wound site through the process of ___.
phagocytosis
Proteases
Thrombin
standards of known properties
44. The formation of rust due to corrosion in the body is due to the reaction between these 3 things ____ - ____ - and ____ .
chemotaxis
Free Radical
Intermolecular bonding - molecular weight
Water - oxygen - metal
45. Collagen ____ is responsible for the gradual gain in mechanical properties of wounded tissue between roughly 4 and 52 weeks post- injury.
cross - linking
Collagenase
cycles
Amide
46. Where are the tissue factors found when they're inactivated
in cytoplasm
Plasticizers
labile cells
Water
47. A condensation polymerization results with an ester bond between two reactants and this comes off as a result
Extrusion
Large
low
Water
48. Deformation that cannot be recovered once the load is removed from the material is ____ deformation.
Regeneration/Repair
Plastic
autologous
Proteases
49. Resulting from the build up of too much collagen at the surface of injury during the granulation tissue stage of proliferation
scars
Hemocompatibility
Stable cells
Collagenase
50. No healing of damage neurons is the result of ____ cells that are not able to ____.
Permanent - replicate
Proteases
micromachining
hypoxin - angiogenesis