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Test your basic knowledge |
Bio Engineering
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Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
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study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Higher Molecular weight degrades slower than ____ MW
Extrusion
low
Collagenase
Lower
2. You're working on a square polymeric implant of 5cm length and 2mm thick. You've been asked to suggest a precise way to fabricate it - what would you suggest?
Compression molding
Proteases
Hemophilia
Negative Feedback
3. In order to produce a blood clot - thrombin cleaves/activates ____ and ____.
mast cells
standards of known properties
fibrinogen - factor XIII
labile cells
4. ____ describes the ability of a device to function appropriately in the presence of blood.
Free Radical
Macrophages
chemotaxis
Hemocompatibility
5. _____ establishes a quantitative relationship between measured output values from an instrument and known standards of what is being measured.
Positive Feedback
Calibration
negative feedback
Lower
6. Is directed cell migration in response to a concentration gradient of soluble molecules.
Phagocytosis
Chemotaxis
Permanent - replicate
Macrophages
7. The calculation of a polymer's molecular weight (weight average and number number average) is based upon values for ____ and ___.
Chemotaxis
Number of polymers - molecular weight of polymer
Free Radical
Amide
8. What types of wound healing results from injury with inflammation?
Water
free radical
Damage to cell membranes
Regeneration/Repair
9. Keloid scars forms because disfuntion of
Phagocytosis
Collagenase
Thrombin
micromachining
10. Mast cells release this
hypoxin - angiogenesis
scars
heparin
photoactive polymers
11. ____ are enzymes responsible for protein degradation.
Allogeneic
Chemotaxis
Lower
Proteases
12. Vascular endothelial growth factor is produced in response to ___ and stimulates ___.
labile cells
Allogeneic
hypoxin - angiogenesis
photoactive polymers
13. What type of materials are used for photolithography? (substrate is a silicon wafer - built up material is some _____ ____ )
photoactive polymers
Regeneration/Repair
Lower
heparin
14. Disfunction of _____ (cells) producing collagenase during the _____ phase of wound healing may form Keloid scars.
Regeneration/Repair
macrophages - proliferation
mast cells
Damage to cell membranes
15. Polyethylene oxide grafting to biomaterials was developed to prevent coagulation by interfering with/preventing ___ ___.
Stable cells
Heparin
Protein Absorption
Damage to cell membranes
16. The fibrous capsule surrounding a permanent implant is primarily composed of ___ cells and ____ (matrix).
Metals
Thrombin
Mast - Collagen
cross - linking
17. ____- are polymers that can be repeatedly softened by heating and hardened by cooling.
Mast - Collagen
Thermoplastics
Plastic
Free Radical
18. Thrombin activates several upstream factors.
hypoxin - angiogenesis
binding
Positive Feedback
Endothelial cells
19. Neutrophils remove bacteria/damaged cell debris from a wound site through the process of ___.
binding
macrophages - proliferation
phagocytosis
Protein Absorption
20. ____ is the process by which cells involved in inflammation internalize and destroy foreign material.
Collagenase/Remodelling
standards of known properties
Chemotaxis
Phagocytosis
21. Enzymes (proteins) are not activated only when they are in contact with this type of cells
Thermoplastics
Endothelial cells
Negative Feedback
Hemophilia
22. The formation of rust due to corrosion in the body is due to the reaction between these 3 things ____ - ____ - and ____ .
Permanent - replicate
low
Water - oxygen - metal
glassy to rubbery
23. The process of calibration establishes a quantitative relationship between ____ __ ___ _____ and the direct output of the intstrument (for example time/volume in GPC).
binding
Phagocytosis
Lower
standards of known properties
24. Cells that proliferate rapidly (fibroblasts)
Permanent - replicate
Phagocytosis
labile cells
Proteases
25. GPC separates molecules on the basis of size by their passage over a column packed with a porous matrix. ___ molecules pass through the column more quickly.
Collagenase
Protein Absorption
Regeneration/Repair
Large
26. Resulting from the build up of too much collagen at the surface of injury during the granulation tissue stage of proliferation
Stable cells
negative feedback
scars
autologous
27. The glass transition temperature of a poymer at which a polymer transforms from a ____ state to a ___ state.
photoactive polymers
glassy to rubbery
heparin
free radical
28. Enzyme that really gets the polmerization going!
Protein Absorption
phagocytosis
Allogeneic
Thrombin
29. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure
Extrusion
Free Radical
Stress
photoactive polymers
30. Type of fiber drawing that controls details of a polymer by etching on a microscopic level; thus - controlling mechanical properties as well
Mast - Collagen
Endothelial cells
micromachining
Collagenase/Remodelling
31. Rather than randomly moving - moves in a directed cell migration manner for specific functions.
Damage to cell membranes
Calibration
chemotaxis
Heparin
32. Cardiac bypass surgery in which a vein from a patient's leg is transplanted to the patient's heart is an example of the us of ____ tissue.
low
autologous
Thrombin
Amide
33. ______ Molecular weight degrades slower than lower MW
free radical
Higher
Amide
Thrombin
34. This type of feedback creates
negative feedback
Mast - Collagen
Thermoplastics
stress
35. No healing of damage neurons is the result of ____ cells that are not able to ____.
Permanent - replicate
chemotaxis
low
Positive Feedback
36. Process of producing new blood vessels due to a lack on oxygen and thus inducing VEGF.
Proteases
angiogenesis
Heparin
Mast - Collagen
37. Thrombin also activates protein C-- which deactivates earlier factors in the cascade is known as ___ ___.
Negative Feedback
neutrophils - macrophages
autologous
Higher
38. Activates tissue factors aka endothelial damage
Damage to cell membranes
Large
alloys - passivation
angiogenesis
39. ____ grafts are derived from the other humans.
Metals
scars
Allogeneic
glassy to rubbery
40. Cell found in the lining of the blood vessels that release heparin and are a part of the negative feedback system.
mast cells
Regeneration/Repair
Enzyme cascade
Thermoplastics
41. Which of polyermization (condensation/free radical) would you choose to obtain a polymer of high molecular weight?
Heparin
Proteases
angiogenesis
Free Radical
42. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure.
Thermoplastics
Intermolecular bonding - molecular weight
Mast - Collagen
stress
43. Drawback of micromaching
Have to be in a clean room free of dust and biocontamination - expensive
Enzyme cascade
chemotaxis
heparin
44. Process that makes long fibers (fiber drawing) by forcing a fluid through an oriface.
Extrusion
chemotaxis
Permanent - replicate
Intermolecular bonding - molecular weight
45. Damaged cells at the site of injury (mast cells) release ___ (glycosaminoglycan).
Collagenase
hypoxin - angiogenesis
Polydesperity index
heparin
46. Foreign body giants cells are produced by fusion of ___.
stress
Permanent - replicate
Macrophages
Mast - Collagen
47. A ____ implant is designed to elicit specific - intended to host responses.
cross - linking
neutrophils - macrophages
Permanent cells
Bioactive
48. The fatigue limit is value of applied stress below which a material will not fail no matter the number of ____ applied.
cycles
Permanent cells
Polymers - cross linking of polymers
Macrophages
49. This cleaves into fibrinogen which creates fibrin (a sticky enzyme that allows blood to clot)
Permanent - replicate
scars
stress
Thrombin
50. ____ is a measurement that characterizes the breadth of the distribution of a polymer's molecular weight.
Polydesperity index
Hemocompatibility
Enzyme cascade
neutrophils - macrophages
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