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Test your basic knowledge |
Bio Engineering
Start Test
Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Higher Molecular weight degrades slower than ____ MW
Lower
angiogenesis
Plastic
cycles
2. Where are the tissue factors found when they're inactivated
Collagenase
Heparin
labile cells
in cytoplasm
3. Process of producing new blood vessels due to a lack on oxygen and thus inducing VEGF.
angiogenesis
Damage to cell membranes
Regeneration/Repair
heparin
4. Addition polymerization is commonly initiated by ___ - atoms that have an unpaired electron.
free radical
Stable cells
Collagenase
Plastic
5. ______ Molecular weight degrades slower than lower MW
labile cells
heparin
Proteases
Higher
6. Vascular endothelial growth factor is produced in response to ___ and stimulates ___.
Enzyme cascade
hypoxin - angiogenesis
photoactive polymers
glassy to rubbery
7. Enzyme that really gets the polmerization going!
Thrombin
Proteases
Damage to cell membranes
Plastic
8. Type of fiber drawing that controls details of a polymer by etching on a microscopic level; thus - controlling mechanical properties as well
Stress
micromachining
heparin
mast cells
9. The formation of rust due to corrosion in the body is due to the reaction between these 3 things ____ - ____ - and ____ .
stress
Water - oxygen - metal
chemotaxis
binding
10. The fatigue limit is value of applied stress below which a material will not fail no matter the number of ____ applied.
cycles
Plasticizers
Large
Metals
11. Disfunction of _____ (cells) producing collagenase during the _____ phase of wound healing may form Keloid scars.
micromachining
photoactive polymers
macrophages - proliferation
autologous
12. Thrombin activates several upstream factors.
Mast - Collagen
photoactive polymers
Positive Feedback
phagocytosis
13. Which of polyermization (condensation/free radical) would you choose to obtain a polymer of high molecular weight?
Stress
Damage to cell membranes
Lower
Free Radical
14. Two things needed in the end product of the creation of a scab
Extrusion
cycles
Polymers - cross linking of polymers
Proteases
15. ____ are enzymes responsible for protein degradation.
Damage to cell membranes
Hemocompatibility
free radical
Proteases
16. No healing of damage neurons is the result of ____ cells that are not able to ____.
Permanent - replicate
Lower
Compression molding
Allogeneic
17. The calculation of a polymer's molecular weight (weight average and number number average) is based upon values for ____ and ___.
free radical
binding
Number of polymers - molecular weight of polymer
Bioactive
18. Thrombin also activates protein C-- which deactivates earlier factors in the cascade is known as ___ ___.
heparin
Hemophilia
Damage to cell membranes
Negative Feedback
19. Condition in which patients can literally bleed to death.
Hemophilia
Number of polymers - molecular weight of polymer
Plasticizers
Chemotaxis
20. A ____ implant is designed to elicit specific - intended to host responses.
Bioactive
Polydesperity index
Positive Feedback
heparin
21. List two chemical characteristics of polymers:
Collagenase
Intermolecular bonding - molecular weight
Macrophages
Thermoplastics
22. The two types of white blood cells:
cycles
neutrophils - macrophages
chemotaxis
Permanent cells
23. Cardiac bypass surgery in which a vein from a patient's leg is transplanted to the patient's heart is an example of the us of ____ tissue.
Have to be in a clean room free of dust and biocontamination - expensive
autologous
free radical
Permanent - replicate
24. ____ is a measurement that characterizes the breadth of the distribution of a polymer's molecular weight.
Stress
Calibration
Polydesperity index
Collagenase
25. You're working on a square polymeric implant of 5cm length and 2mm thick. You've been asked to suggest a precise way to fabricate it - what would you suggest?
in cytoplasm
Thrombin
Thermoplastics
Compression molding
26. What type of materials are used for photolithography? (substrate is a silicon wafer - built up material is some _____ ____ )
photoactive polymers
Extrusion
angiogenesis
Enzyme cascade
27. Cell found in the lining of the blood vessels that release heparin and are a part of the negative feedback system.
Regeneration/Repair
Protein Absorption
heparin
mast cells
28. Activates tissue factors aka endothelial damage
binding
Damage to cell membranes
Proteases
cross - linking
29. Essentially all metallic biomaterials are ____ - comprised of two or more metals. One of these metals is selected for its ability to support _____ - the formation of a stable oxide layer that resists further corrosion.
cycles
Positive Feedback
macrophages - proliferation
alloys - passivation
30. High conductivity - isotropic - crystalline
Heparin
Metals
Endothelial cells
Extrusion
31. Polyethylene oxide grafting to biomaterials was developed to prevent coagulation by interfering with/preventing ___ ___.
Stable cells
alloys - passivation
Protein Absorption
Higher
32. A condensation polymerization results with an ester bond between two reactants and this comes off as a result
cross - linking
stress
cycles
Water
33. Deformation that cannot be recovered once the load is removed from the material is ____ deformation.
Stable cells
Hemophilia
Plastic
cross - linking
34. Drawback of micromaching
fibrinogen - factor XIII
Have to be in a clean room free of dust and biocontamination - expensive
Allogeneic
chemotaxis
35. Neutrophils remove bacteria/damaged cell debris from a wound site through the process of ___.
Allogeneic
Intermolecular bonding - molecular weight
chemotaxis
phagocytosis
36. Foreign body giants cells are produced by fusion of ___.
Macrophages
Number of polymers - molecular weight of polymer
negative feedback
Extrusion
37. The glass transition temperature of a poymer at which a polymer transforms from a ____ state to a ___ state.
Endothelial cells
glassy to rubbery
macrophages - proliferation
Water - oxygen - metal
38. Rather than randomly moving - moves in a directed cell migration manner for specific functions.
chemotaxis
standards of known properties
cycles
Proteases
39. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure.
Damage to cell membranes
mast cells
Water - oxygen - metal
stress
40. The fibrous capsule surrounding a permanent implant is primarily composed of ___ cells and ____ (matrix).
Mast - Collagen
Permanent - replicate
Water - oxygen - metal
fibrinogen - factor XIII
41. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure
Mast - Collagen
phagocytosis
Stress
Collagenase
42. During granulation stage of proliferation - growth factors that produce this ____(answer)_____ that function in degrading fibrin and replacing it with collagen.
Regeneration/Repair
negative feedback
Proteases
Plasticizers
43. Collagen ____ is responsible for the gradual gain in mechanical properties of wounded tissue between roughly 4 and 52 weeks post- injury.
Permanent - replicate
Metals
Thrombin
cross - linking
44. GPC separates molecules on the basis of size by their passage over a column packed with a porous matrix. ___ molecules pass through the column more quickly.
Large
Thrombin
Plastic
Bioactive
45. ____ describes the ability of a device to function appropriately in the presence of blood.
Collagenase/Remodelling
Number of polymers - molecular weight of polymer
Hemocompatibility
Plastic
46. Enzymes (proteins) are not activated only when they are in contact with this type of cells
Polymers - cross linking of polymers
Endothelial cells
photoactive polymers
alloys - passivation
47. Damaged cells at the site of injury (mast cells) release ___ (glycosaminoglycan).
heparin
Thrombin
Extrusion
Free Radical
48. ____ binds to anti- thrombin III (thrombin inhibitor) and increases its potency 1000- fold.
Heparin
Lower
Metals
Protein Absorption
49. This type of feedback creates
fibrinogen - factor XIII
negative feedback
alloys - passivation
autologous
50. Are polymer additives used to lower glass transition temperature temperature.
Plasticizers
Hemocompatibility
glassy to rubbery
Damage to cell membranes