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Test your basic knowledge |
Bio Engineering
Start Test
Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Keloid scars forms because disfuntion of
Collagenase
standards of known properties
hypoxin - angiogenesis
Phagocytosis
2. Cells that proliferate slowly over time (aka liver)
Water
Stable cells
Proteases
phagocytosis
3. Classify the following polymers into appropriate families based on their bond structure i.e. the polymer is an example of poly ____.
Amide
Collagenase/Remodelling
heparin
autologous
4. Disfunction of _____ (cells) producing collagenase during the _____ phase of wound healing may form Keloid scars.
Calibration
macrophages - proliferation
negative feedback
Stress
5. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure.
micromachining
stress
Phagocytosis
Thrombin
6. Thrombin also activates protein C-- which deactivates earlier factors in the cascade is known as ___ ___.
Thrombin
phagocytosis
Collagenase
Negative Feedback
7. Are polymer additives used to lower glass transition temperature temperature.
Plasticizers
Bioactive
Large
Lower
8. Cardiac bypass surgery in which a vein from a patient's leg is transplanted to the patient's heart is an example of the us of ____ tissue.
in cytoplasm
autologous
Metals
Protein Absorption
9. Enzyme that really gets the polmerization going!
Compression molding
Thrombin
angiogenesis
cross - linking
10. Neutrophils remove bacteria/damaged cell debris from a wound site through the process of ___.
Proteases
Damage to cell membranes
heparin
phagocytosis
11. ____ is the process by which cells involved in inflammation internalize and destroy foreign material.
Stress
cross - linking
Phagocytosis
in cytoplasm
12. The process of calibration establishes a quantitative relationship between ____ __ ___ _____ and the direct output of the intstrument (for example time/volume in GPC).
Mast - Collagen
Amide
Extrusion
standards of known properties
13. Cells that proliferate rapidly (fibroblasts)
Calibration
Number of polymers - molecular weight of polymer
labile cells
Positive Feedback
14. Deformation that cannot be recovered once the load is removed from the material is ____ deformation.
Plastic
in cytoplasm
Large
Polydesperity index
15. During granulation stage of proliferation - growth factors that produce this ____(answer)_____ that function in degrading fibrin and replacing it with collagen.
Proteases
chemotaxis
in cytoplasm
Water
16. Addition polymerization is commonly initiated by ___ - atoms that have an unpaired electron.
Enzyme cascade
free radical
glassy to rubbery
photoactive polymers
17. The fibrous capsule surrounding a permanent implant is primarily composed of ___ cells and ____ (matrix).
Proteases
Mast - Collagen
Thrombin
Positive Feedback
18. You're working on a square polymeric implant of 5cm length and 2mm thick. You've been asked to suggest a precise way to fabricate it - what would you suggest?
Compression molding
glassy to rubbery
phagocytosis
Water
19. What types of wound healing results from injury with inflammation?
Regeneration/Repair
cycles
standards of known properties
phagocytosis
20. No healing of damage neurons is the result of ____ cells that are not able to ____.
Intermolecular bonding - molecular weight
Collagenase
Stable cells
Permanent - replicate
21. ____- are polymers that can be repeatedly softened by heating and hardened by cooling.
Proteases
Amide
standards of known properties
Thermoplastics
22. Is directed cell migration in response to a concentration gradient of soluble molecules.
Chemotaxis
cycles
stress
Heparin
23. Foreign body giants cells are produced by fusion of ___.
Allogeneic
Water - oxygen - metal
Macrophages
phagocytosis
24. Activates tissue factors aka endothelial damage
Damage to cell membranes
phagocytosis
micromachining
Chemotaxis
25. Resulting from the build up of too much collagen at the surface of injury during the granulation tissue stage of proliferation
heparin
photoactive polymers
scars
phagocytosis
26. ______ Molecular weight degrades slower than lower MW
Extrusion
Higher
Damage to cell membranes
angiogenesis
27. The fatigue limit is value of applied stress below which a material will not fail no matter the number of ____ applied.
Thermoplastics
cycles
hypoxin - angiogenesis
Endothelial cells
28. The trigger for activation of enzymes (anything but endothelial cells!)
Permanent cells
binding
Negative Feedback
macrophages - proliferation
29. Polyethylene oxide grafting to biomaterials was developed to prevent coagulation by interfering with/preventing ___ ___.
Number of polymers - molecular weight of polymer
Permanent cells
Protein Absorption
in cytoplasm
30. ____ grafts are derived from the other humans.
Allogeneic
autologous
Stress
Collagenase
31. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure
Polydesperity index
Metals
Stress
Stable cells
32. Process that makes long fibers (fiber drawing) by forcing a fluid through an oriface.
Extrusion
angiogenesis
Calibration
Thrombin
33. Rather than randomly moving - moves in a directed cell migration manner for specific functions.
Higher
Water - oxygen - metal
Thermoplastics
chemotaxis
34. ____ describes the ability of a device to function appropriately in the presence of blood.
Have to be in a clean room free of dust and biocontamination - expensive
Higher
Negative Feedback
Hemocompatibility
35. Drawback of micromaching
Have to be in a clean room free of dust and biocontamination - expensive
Allogeneic
negative feedback
Protein Absorption
36. List two chemical characteristics of polymers:
angiogenesis
Chemotaxis
Higher
Intermolecular bonding - molecular weight
37. In order to produce a blood clot - thrombin cleaves/activates ____ and ____.
Positive Feedback
fibrinogen - factor XIII
Heparin
Water
38. Higher Molecular weight degrades slower than ____ MW
Mast - Collagen
Lower
scars
Number of polymers - molecular weight of polymer
39. A condensation polymerization results with an ester bond between two reactants and this comes off as a result
Regeneration/Repair
Proteases
Water
Thrombin
40. Damaged cells at the site of injury (mast cells) release ___ (glycosaminoglycan).
chemotaxis
Proteases
heparin
Permanent - replicate
41. Collagen ____ is responsible for the gradual gain in mechanical properties of wounded tissue between roughly 4 and 52 weeks post- injury.
cross - linking
Damage to cell membranes
Mast - Collagen
Lower
42. A ____ implant is designed to elicit specific - intended to host responses.
Water
Hemophilia
Bioactive
Proteases
43. Which of polyermization (condensation/free radical) would you choose to obtain a polymer of high molecular weight?
scars
Polymers - cross linking of polymers
Free Radical
Extrusion
44. Enzymes (proteins) are not activated only when they are in contact with this type of cells
angiogenesis
Amide
Endothelial cells
Collagenase
45. Relative to free radical polymerization - condensation polymerization generally produces polymer of relatively ____ molecular weight.
Intermolecular bonding - molecular weight
Thrombin
micromachining
low
46. This cleaves into fibrinogen which creates fibrin (a sticky enzyme that allows blood to clot)
Allogeneic
Thrombin
Polydesperity index
Hemocompatibility
47. What type of materials are used for photolithography? (substrate is a silicon wafer - built up material is some _____ ____ )
alloys - passivation
binding
photoactive polymers
Amide
48. ____ is a measurement that characterizes the breadth of the distribution of a polymer's molecular weight.
Polydesperity index
Allogeneic
Proteases
Protein Absorption
49. Vascular endothelial growth factor is produced in response to ___ and stimulates ___.
Negative Feedback
Bioactive
micromachining
hypoxin - angiogenesis
50. Where are the tissue factors found when they're inactivated
in cytoplasm
free radical
Allogeneic
autologous