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Test your basic knowledge |
Bio Engineering
Start Test
Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Polyethylene oxide grafting to biomaterials was developed to prevent coagulation by interfering with/preventing ___ ___.
Stress
Collagenase/Remodelling
hypoxin - angiogenesis
Protein Absorption
2. Neutrophils remove bacteria/damaged cell debris from a wound site through the process of ___.
Mast - Collagen
binding
phagocytosis
autologous
3. ______ Molecular weight degrades slower than lower MW
Higher
Endothelial cells
Mast - Collagen
Phagocytosis
4. You're working on a square polymeric implant of 5cm length and 2mm thick. You've been asked to suggest a precise way to fabricate it - what would you suggest?
Compression molding
Number of polymers - molecular weight of polymer
cross - linking
neutrophils - macrophages
5. Rather than randomly moving - moves in a directed cell migration manner for specific functions.
in cytoplasm
Permanent - replicate
Free Radical
chemotaxis
6. Process that makes long fibers (fiber drawing) by forcing a fluid through an oriface.
Extrusion
Compression molding
micromachining
negative feedback
7. A ____ implant is designed to elicit specific - intended to host responses.
Bioactive
Collagenase/Remodelling
Free Radical
Stress
8. Process of producing new blood vessels due to a lack on oxygen and thus inducing VEGF.
Have to be in a clean room free of dust and biocontamination - expensive
angiogenesis
Positive Feedback
Calibration
9. Drawback of micromaching
Have to be in a clean room free of dust and biocontamination - expensive
macrophages - proliferation
cross - linking
Damage to cell membranes
10. GPC separates molecules on the basis of size by their passage over a column packed with a porous matrix. ___ molecules pass through the column more quickly.
Large
Negative Feedback
alloys - passivation
Plasticizers
11. This cleaves into fibrinogen which creates fibrin (a sticky enzyme that allows blood to clot)
chemotaxis
Thrombin
cycles
Enzyme cascade
12. _____ establishes a quantitative relationship between measured output values from an instrument and known standards of what is being measured.
Calibration
angiogenesis
negative feedback
labile cells
13. Resulting from the build up of too much collagen at the surface of injury during the granulation tissue stage of proliferation
Plastic
scars
macrophages - proliferation
Heparin
14. Foreign body giants cells are produced by fusion of ___.
Protein Absorption
Collagenase/Remodelling
Permanent - replicate
Macrophages
15. ____ is the process by which cells involved in inflammation internalize and destroy foreign material.
standards of known properties
Macrophages
Thrombin
Phagocytosis
16. ____- are polymers that can be repeatedly softened by heating and hardened by cooling.
angiogenesis
hypoxin - angiogenesis
Thermoplastics
autologous
17. The process of calibration establishes a quantitative relationship between ____ __ ___ _____ and the direct output of the intstrument (for example time/volume in GPC).
micromachining
Positive Feedback
standards of known properties
macrophages - proliferation
18. Condition in which patients can literally bleed to death.
alloys - passivation
Hemophilia
low
Endothelial cells
19. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure
heparin
Permanent cells
micromachining
Stress
20. Is directed cell migration in response to a concentration gradient of soluble molecules.
Water - oxygen - metal
Chemotaxis
phagocytosis
binding
21. ____ are enzymes responsible for protein degradation.
Proteases
chemotaxis
Allogeneic
Free Radical
22. This type of feedback creates
negative feedback
neutrophils - macrophages
Regeneration/Repair
Allogeneic
23. Cells that proliferate slowly over time (aka liver)
Stable cells
Plasticizers
heparin
alloys - passivation
24. The calculation of a polymer's molecular weight (weight average and number number average) is based upon values for ____ and ___.
Number of polymers - molecular weight of polymer
Extrusion
Positive Feedback
low
25. Cell found in the lining of the blood vessels that release heparin and are a part of the negative feedback system.
micromachining
Protein Absorption
mast cells
in cytoplasm
26. Cells that proliferate rapidly (fibroblasts)
chemotaxis
labile cells
Positive Feedback
Free Radical
27. Thrombin also activates protein C-- which deactivates earlier factors in the cascade is known as ___ ___.
Hemocompatibility
heparin
alloys - passivation
Negative Feedback
28. Thrombin activates several upstream factors.
Positive Feedback
Collagenase
Bioactive
Stable cells
29. Which of polyermization (condensation/free radical) would you choose to obtain a polymer of high molecular weight?
cross - linking
Collagenase/Remodelling
Free Radical
Heparin
30. What types of wound healing results from injury with inflammation?
Water
Regeneration/Repair
Stress
heparin
31. No healing of damage neurons is the result of ____ cells that are not able to ____.
Permanent - replicate
cross - linking
free radical
Large
32. Mast cells release this
heparin
photoactive polymers
Metals
Compression molding
33. In order to produce a blood clot - thrombin cleaves/activates ____ and ____.
stress
Water - oxygen - metal
fibrinogen - factor XIII
Permanent - replicate
34. A molecular pathway in which the product of each reaction catalyzes the subsequent reaction.
Enzyme cascade
Thermoplastics
standards of known properties
scars
35. During granulation stage of proliferation - growth factors that produce this ____(answer)_____ that function in degrading fibrin and replacing it with collagen.
Stable cells
Thrombin
Macrophages
Proteases
36. Disfunction of _____ (cells) producing collagenase during the _____ phase of wound healing may form Keloid scars.
Collagenase
Proteases
macrophages - proliferation
Stress
37. Keloid scars forms because disfuntion of
cross - linking
Thermoplastics
Metals
Collagenase
38. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure.
Permanent cells
Plasticizers
low
stress
39. Are polymer additives used to lower glass transition temperature temperature.
Plasticizers
Regeneration/Repair
alloys - passivation
Calibration
40. ____ describes the ability of a device to function appropriately in the presence of blood.
autologous
Hemocompatibility
Proteases
Number of polymers - molecular weight of polymer
41. Type of fiber drawing that controls details of a polymer by etching on a microscopic level; thus - controlling mechanical properties as well
Mast - Collagen
Polydesperity index
micromachining
Amide
42. Vascular endothelial growth factor is produced in response to ___ and stimulates ___.
Permanent - replicate
autologous
Thermoplastics
hypoxin - angiogenesis
43. The fibrous capsule surrounding a permanent implant is primarily composed of ___ cells and ____ (matrix).
Mast - Collagen
standards of known properties
Compression molding
in cytoplasm
44. ____ binds to anti- thrombin III (thrombin inhibitor) and increases its potency 1000- fold.
Heparin
Lower
Hemophilia
binding
45. The trigger for activation of enzymes (anything but endothelial cells!)
Permanent - replicate
Stress
scars
binding
46. Two things needed in the end product of the creation of a scab
negative feedback
Polymers - cross linking of polymers
cross - linking
Phagocytosis
47. Cardiac bypass surgery in which a vein from a patient's leg is transplanted to the patient's heart is an example of the us of ____ tissue.
Phagocytosis
autologous
Chemotaxis
labile cells
48. Cells that don't proliferate (neurons)
Water
Collagenase/Remodelling
cross - linking
Permanent cells
49. The glass transition temperature of a poymer at which a polymer transforms from a ____ state to a ___ state.
heparin
Collagenase/Remodelling
heparin
glassy to rubbery
50. Relative to free radical polymerization - condensation polymerization generally produces polymer of relatively ____ molecular weight.
binding
Amide
low
Extrusion