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Test your basic knowledge |
Bio Engineering
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Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Essentially all metallic biomaterials are ____ - comprised of two or more metals. One of these metals is selected for its ability to support _____ - the formation of a stable oxide layer that resists further corrosion.
Proteases
cross - linking
Number of polymers - molecular weight of polymer
alloys - passivation
2. The fibrous capsule surrounding a permanent implant is primarily composed of ___ cells and ____ (matrix).
Compression molding
stress
Plastic
Mast - Collagen
3. ____ is the process by which cells involved in inflammation internalize and destroy foreign material.
Thrombin
Phagocytosis
Regeneration/Repair
Macrophages
4. ____ binds to anti- thrombin III (thrombin inhibitor) and increases its potency 1000- fold.
Amide
Water
Proteases
Heparin
5. Damaged cells at the site of injury (mast cells) release ___ (glycosaminoglycan).
Polydesperity index
heparin
fibrinogen - factor XIII
Plasticizers
6. The trigger for activation of enzymes (anything but endothelial cells!)
binding
low
Collagenase
Stable cells
7. Cell found in the lining of the blood vessels that release heparin and are a part of the negative feedback system.
Amide
stress
Negative Feedback
mast cells
8. Cells that proliferate rapidly (fibroblasts)
Have to be in a clean room free of dust and biocontamination - expensive
Hemocompatibility
labile cells
Plasticizers
9. The calculation of a polymer's molecular weight (weight average and number number average) is based upon values for ____ and ___.
Enzyme cascade
Number of polymers - molecular weight of polymer
Higher
stress
10. Condition in which patients can literally bleed to death.
low
mast cells
Hemophilia
Bioactive
11. GPC separates molecules on the basis of size by their passage over a column packed with a porous matrix. ___ molecules pass through the column more quickly.
Large
Phagocytosis
Permanent cells
Collagenase/Remodelling
12. Activates tissue factors aka endothelial damage
neutrophils - macrophages
Have to be in a clean room free of dust and biocontamination - expensive
Damage to cell membranes
glassy to rubbery
13. Enzymes (proteins) are not activated only when they are in contact with this type of cells
standards of known properties
Phagocytosis
Endothelial cells
Higher
14. The process of calibration establishes a quantitative relationship between ____ __ ___ _____ and the direct output of the intstrument (for example time/volume in GPC).
standards of known properties
Proteases
micromachining
glassy to rubbery
15. High conductivity - isotropic - crystalline
Hemophilia
Thrombin
Amide
Metals
16. No healing of damage neurons is the result of ____ cells that are not able to ____.
Intermolecular bonding - molecular weight
Permanent - replicate
hypoxin - angiogenesis
labile cells
17. You're working on a square polymeric implant of 5cm length and 2mm thick. You've been asked to suggest a precise way to fabricate it - what would you suggest?
Compression molding
Water
Chemotaxis
cycles
18. Relative to free radical polymerization - condensation polymerization generally produces polymer of relatively ____ molecular weight.
Extrusion
Damage to cell membranes
Chemotaxis
low
19. ____ grafts are derived from the other humans.
standards of known properties
angiogenesis
Allogeneic
Macrophages
20. Cardiac bypass surgery in which a vein from a patient's leg is transplanted to the patient's heart is an example of the us of ____ tissue.
labile cells
glassy to rubbery
Stable cells
autologous
21. Resulting from the build up of too much collagen at the surface of injury during the granulation tissue stage of proliferation
hypoxin - angiogenesis
Thrombin
Intermolecular bonding - molecular weight
scars
22. Cells that proliferate slowly over time (aka liver)
Enzyme cascade
Water - oxygen - metal
Stable cells
Permanent cells
23. Classify the following polymers into appropriate families based on their bond structure i.e. the polymer is an example of poly ____.
Water
Regeneration/Repair
Amide
macrophages - proliferation
24. Two things needed in the end product of the creation of a scab
Polymers - cross linking of polymers
Allogeneic
Water
Regeneration/Repair
25. Enzyme that really gets the polmerization going!
alloys - passivation
Higher
phagocytosis
Thrombin
26. A condensation polymerization results with an ester bond between two reactants and this comes off as a result
Water
Bioactive
Heparin
in cytoplasm
27. Foreign body giants cells are produced by fusion of ___.
binding
Macrophages
Heparin
Thermoplastics
28. Process of producing new blood vessels due to a lack on oxygen and thus inducing VEGF.
angiogenesis
Stress
Polymers - cross linking of polymers
Enzyme cascade
29. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure
Protein Absorption
Extrusion
Stress
glassy to rubbery
30. Cells that don't proliferate (neurons)
cross - linking
fibrinogen - factor XIII
Polymers - cross linking of polymers
Permanent cells
31. In order to produce a blood clot - thrombin cleaves/activates ____ and ____.
fibrinogen - factor XIII
neutrophils - macrophages
photoactive polymers
Hemocompatibility
32. The two types of white blood cells:
neutrophils - macrophages
stress
Higher
chemotaxis
33. The glass transition temperature of a poymer at which a polymer transforms from a ____ state to a ___ state.
stress
cross - linking
Thrombin
glassy to rubbery
34. ______ Molecular weight degrades slower than lower MW
Higher
Water
macrophages - proliferation
cross - linking
35. Type of fiber drawing that controls details of a polymer by etching on a microscopic level; thus - controlling mechanical properties as well
micromachining
Collagenase
Phagocytosis
cross - linking
36. Thrombin activates several upstream factors.
alloys - passivation
Positive Feedback
Higher
glassy to rubbery
37. Keloid scars form due to disfunction of ____.
Higher
stress
Collagenase/Remodelling
Stable cells
38. The formation of rust due to corrosion in the body is due to the reaction between these 3 things ____ - ____ - and ____ .
Water - oxygen - metal
Thermoplastics
low
Enzyme cascade
39. Addition polymerization is commonly initiated by ___ - atoms that have an unpaired electron.
low
heparin
Compression molding
free radical
40. ____ are enzymes responsible for protein degradation.
Proteases
heparin
Permanent - replicate
Enzyme cascade
41. This type of feedback creates
Positive Feedback
fibrinogen - factor XIII
negative feedback
alloys - passivation
42. Process that makes long fibers (fiber drawing) by forcing a fluid through an oriface.
alloys - passivation
Polymers - cross linking of polymers
Extrusion
Intermolecular bonding - molecular weight
43. Which of polyermization (condensation/free radical) would you choose to obtain a polymer of high molecular weight?
Free Radical
Macrophages
neutrophils - macrophages
heparin
44. Collagen ____ is responsible for the gradual gain in mechanical properties of wounded tissue between roughly 4 and 52 weeks post- injury.
cross - linking
scars
in cytoplasm
Water
45. A molecular pathway in which the product of each reaction catalyzes the subsequent reaction.
Negative Feedback
Enzyme cascade
Polymers - cross linking of polymers
Lower
46. Is directed cell migration in response to a concentration gradient of soluble molecules.
heparin
Chemotaxis
Proteases
Hemocompatibility
47. _____ establishes a quantitative relationship between measured output values from an instrument and known standards of what is being measured.
micromachining
Stable cells
Calibration
Hemocompatibility
48. What type of materials are used for photolithography? (substrate is a silicon wafer - built up material is some _____ ____ )
photoactive polymers
heparin
Chemotaxis
binding
49. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure.
Lower
stress
Collagenase/Remodelling
Phagocytosis
50. Thrombin also activates protein C-- which deactivates earlier factors in the cascade is known as ___ ___.
Plasticizers
Allogeneic
Negative Feedback
Damage to cell membranes
Sorry!:) No result found.
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