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Test your basic knowledge |
Bio Engineering
Start Test
Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. ____ binds to anti- thrombin III (thrombin inhibitor) and increases its potency 1000- fold.
Polydesperity index
Intermolecular bonding - molecular weight
Heparin
free radical
2. Collagen ____ is responsible for the gradual gain in mechanical properties of wounded tissue between roughly 4 and 52 weeks post- injury.
Free Radical
low
Thermoplastics
cross - linking
3. Drawback of micromaching
Collagenase
Have to be in a clean room free of dust and biocontamination - expensive
Water - oxygen - metal
Permanent - replicate
4. ____- are polymers that can be repeatedly softened by heating and hardened by cooling.
Thermoplastics
macrophages - proliferation
Regeneration/Repair
Bioactive
5. _____ establishes a quantitative relationship between measured output values from an instrument and known standards of what is being measured.
Plasticizers
Thrombin
Calibration
Permanent - replicate
6. Deformation that cannot be recovered once the load is removed from the material is ____ deformation.
Mast - Collagen
Allogeneic
Plastic
Permanent cells
7. Cardiac bypass surgery in which a vein from a patient's leg is transplanted to the patient's heart is an example of the us of ____ tissue.
Proteases
heparin
photoactive polymers
autologous
8. Higher Molecular weight degrades slower than ____ MW
Polydesperity index
Lower
Mast - Collagen
Positive Feedback
9. Keloid scars forms because disfuntion of
chemotaxis
Bioactive
Collagenase
Metals
10. GPC separates molecules on the basis of size by their passage over a column packed with a porous matrix. ___ molecules pass through the column more quickly.
cycles
Phagocytosis
heparin
Large
11. Mast cells release this
heparin
Proteases
micromachining
Intermolecular bonding - molecular weight
12. Thrombin activates several upstream factors.
alloys - passivation
Water - oxygen - metal
Positive Feedback
labile cells
13. Disfunction of _____ (cells) producing collagenase during the _____ phase of wound healing may form Keloid scars.
macrophages - proliferation
chemotaxis
angiogenesis
Regeneration/Repair
14. ____ are enzymes responsible for protein degradation.
Polymers - cross linking of polymers
Large
photoactive polymers
Proteases
15. In order to produce a blood clot - thrombin cleaves/activates ____ and ____.
Heparin
fibrinogen - factor XIII
Polymers - cross linking of polymers
Mast - Collagen
16. You're working on a square polymeric implant of 5cm length and 2mm thick. You've been asked to suggest a precise way to fabricate it - what would you suggest?
Stable cells
Endothelial cells
Compression molding
Collagenase
17. Cells that proliferate rapidly (fibroblasts)
Damage to cell membranes
labile cells
Mast - Collagen
Hemocompatibility
18. Which of polyermization (condensation/free radical) would you choose to obtain a polymer of high molecular weight?
Stress
Positive Feedback
neutrophils - macrophages
Free Radical
19. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure
Higher
Proteases
Stress
Thrombin
20. Activates tissue factors aka endothelial damage
micromachining
Damage to cell membranes
Regeneration/Repair
Lower
21. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure.
macrophages - proliferation
Enzyme cascade
stress
Higher
22. Cells that proliferate slowly over time (aka liver)
mast cells
Water
Stable cells
negative feedback
23. Enzymes (proteins) are not activated only when they are in contact with this type of cells
Endothelial cells
phagocytosis
Damage to cell membranes
Water - oxygen - metal
24. Keloid scars form due to disfunction of ____.
Collagenase/Remodelling
Stress
mast cells
cycles
25. ____ is the process by which cells involved in inflammation internalize and destroy foreign material.
Phagocytosis
Proteases
Proteases
Plasticizers
26. Rather than randomly moving - moves in a directed cell migration manner for specific functions.
free radical
Protein Absorption
Permanent - replicate
chemotaxis
27. Relative to free radical polymerization - condensation polymerization generally produces polymer of relatively ____ molecular weight.
low
scars
Heparin
stress
28. A condensation polymerization results with an ester bond between two reactants and this comes off as a result
heparin
Bioactive
Water
Have to be in a clean room free of dust and biocontamination - expensive
29. This cleaves into fibrinogen which creates fibrin (a sticky enzyme that allows blood to clot)
Thrombin
Calibration
Water
Endothelial cells
30. Condition in which patients can literally bleed to death.
angiogenesis
Extrusion
Collagenase
Hemophilia
31. Where are the tissue factors found when they're inactivated
phagocytosis
angiogenesis
Enzyme cascade
in cytoplasm
32. Cells that don't proliferate (neurons)
Chemotaxis
micromachining
Metals
Permanent cells
33. What type of materials are used for photolithography? (substrate is a silicon wafer - built up material is some _____ ____ )
Protein Absorption
photoactive polymers
Regeneration/Repair
Bioactive
34. ____ grafts are derived from the other humans.
Permanent - replicate
Permanent cells
Plasticizers
Allogeneic
35. This type of feedback creates
Calibration
negative feedback
alloys - passivation
Have to be in a clean room free of dust and biocontamination - expensive
36. List two chemical characteristics of polymers:
Extrusion
Intermolecular bonding - molecular weight
autologous
Damage to cell membranes
37. Neutrophils remove bacteria/damaged cell debris from a wound site through the process of ___.
free radical
Permanent - replicate
Mast - Collagen
phagocytosis
38. No healing of damage neurons is the result of ____ cells that are not able to ____.
Proteases
Permanent - replicate
Phagocytosis
macrophages - proliferation
39. What types of wound healing results from injury with inflammation?
Hemophilia
Permanent - replicate
Positive Feedback
Regeneration/Repair
40. The process of calibration establishes a quantitative relationship between ____ __ ___ _____ and the direct output of the intstrument (for example time/volume in GPC).
stress
Lower
Free Radical
standards of known properties
41. Damaged cells at the site of injury (mast cells) release ___ (glycosaminoglycan).
Mast - Collagen
photoactive polymers
Plasticizers
heparin
42. A molecular pathway in which the product of each reaction catalyzes the subsequent reaction.
Large
Heparin
scars
Enzyme cascade
43. A ____ implant is designed to elicit specific - intended to host responses.
Bioactive
fibrinogen - factor XIII
Water - oxygen - metal
scars
44. Resulting from the build up of too much collagen at the surface of injury during the granulation tissue stage of proliferation
Enzyme cascade
Free Radical
Compression molding
scars
45. The fatigue limit is value of applied stress below which a material will not fail no matter the number of ____ applied.
Bioactive
cycles
fibrinogen - factor XIII
Macrophages
46. Thrombin also activates protein C-- which deactivates earlier factors in the cascade is known as ___ ___.
hypoxin - angiogenesis
Stress
alloys - passivation
Negative Feedback
47. The formation of rust due to corrosion in the body is due to the reaction between these 3 things ____ - ____ - and ____ .
Water - oxygen - metal
Amide
Positive Feedback
Collagenase/Remodelling
48. During granulation stage of proliferation - growth factors that produce this ____(answer)_____ that function in degrading fibrin and replacing it with collagen.
alloys - passivation
Calibration
Water
Proteases
49. Are polymer additives used to lower glass transition temperature temperature.
Heparin
Number of polymers - molecular weight of polymer
Calibration
Plasticizers
50. ______ Molecular weight degrades slower than lower MW
Plasticizers
Higher
macrophages - proliferation
cross - linking