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Bio Engineering
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Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. This type of feedback creates
negative feedback
Metals
in cytoplasm
labile cells
2. Higher Molecular weight degrades slower than ____ MW
fibrinogen - factor XIII
Hemophilia
Lower
Regeneration/Repair
3. Keloid scars form due to disfunction of ____.
Collagenase/Remodelling
mast cells
Extrusion
Endothelial cells
4. No healing of damage neurons is the result of ____ cells that are not able to ____.
Permanent - replicate
cycles
chemotaxis
glassy to rubbery
5. Enzyme that really gets the polmerization going!
Number of polymers - molecular weight of polymer
Thrombin
Negative Feedback
Water - oxygen - metal
6. Damaged cells at the site of injury (mast cells) release ___ (glycosaminoglycan).
Large
mast cells
heparin
photoactive polymers
7. GPC separates molecules on the basis of size by their passage over a column packed with a porous matrix. ___ molecules pass through the column more quickly.
Mast - Collagen
Protein Absorption
Water
Large
8. Resulting from the build up of too much collagen at the surface of injury during the granulation tissue stage of proliferation
autologous
Stress
scars
chemotaxis
9. Process of producing new blood vessels due to a lack on oxygen and thus inducing VEGF.
Macrophages
angiogenesis
cycles
cross - linking
10. You're working on a square polymeric implant of 5cm length and 2mm thick. You've been asked to suggest a precise way to fabricate it - what would you suggest?
Compression molding
photoactive polymers
Stable cells
macrophages - proliferation
11. Relative to free radical polymerization - condensation polymerization generally produces polymer of relatively ____ molecular weight.
Number of polymers - molecular weight of polymer
low
autologous
Permanent - replicate
12. Cells that proliferate slowly over time (aka liver)
binding
Collagenase/Remodelling
Stable cells
fibrinogen - factor XIII
13. The two types of white blood cells:
Negative Feedback
Higher
in cytoplasm
neutrophils - macrophages
14. A ____ implant is designed to elicit specific - intended to host responses.
Proteases
standards of known properties
Negative Feedback
Bioactive
15. Classify the following polymers into appropriate families based on their bond structure i.e. the polymer is an example of poly ____.
autologous
Positive Feedback
scars
Amide
16. List two chemical characteristics of polymers:
chemotaxis
Intermolecular bonding - molecular weight
cycles
Proteases
17. Deformation that cannot be recovered once the load is removed from the material is ____ deformation.
Plastic
Proteases
Proteases
Damage to cell membranes
18. Mast cells release this
hypoxin - angiogenesis
heparin
neutrophils - macrophages
Proteases
19. ____- are polymers that can be repeatedly softened by heating and hardened by cooling.
Stable cells
Thrombin
low
Thermoplastics
20. Keloid scars forms because disfuntion of
Regeneration/Repair
Heparin
Thermoplastics
Collagenase
21. Foreign body giants cells are produced by fusion of ___.
Macrophages
Metals
Amide
Mast - Collagen
22. Neutrophils remove bacteria/damaged cell debris from a wound site through the process of ___.
micromachining
Endothelial cells
phagocytosis
Thermoplastics
23. Rather than randomly moving - moves in a directed cell migration manner for specific functions.
chemotaxis
Protein Absorption
Proteases
Stress
24. Vascular endothelial growth factor is produced in response to ___ and stimulates ___.
stress
Stable cells
hypoxin - angiogenesis
Permanent - replicate
25. Which of polyermization (condensation/free radical) would you choose to obtain a polymer of high molecular weight?
Free Radical
alloys - passivation
Chemotaxis
Number of polymers - molecular weight of polymer
26. Process that makes long fibers (fiber drawing) by forcing a fluid through an oriface.
Extrusion
free radical
Thermoplastics
Stable cells
27. Collagen ____ is responsible for the gradual gain in mechanical properties of wounded tissue between roughly 4 and 52 weeks post- injury.
Mast - Collagen
Intermolecular bonding - molecular weight
hypoxin - angiogenesis
cross - linking
28. The calculation of a polymer's molecular weight (weight average and number number average) is based upon values for ____ and ___.
Plasticizers
Number of polymers - molecular weight of polymer
Phagocytosis
Hemocompatibility
29. Cells that don't proliferate (neurons)
glassy to rubbery
standards of known properties
Permanent cells
Free Radical
30. Where are the tissue factors found when they're inactivated
Number of polymers - molecular weight of polymer
Water
in cytoplasm
Heparin
31. In order to produce a blood clot - thrombin cleaves/activates ____ and ____.
heparin
fibrinogen - factor XIII
Plasticizers
Regeneration/Repair
32. Condition in which patients can literally bleed to death.
neutrophils - macrophages
Hemophilia
Macrophages
photoactive polymers
33. This cleaves into fibrinogen which creates fibrin (a sticky enzyme that allows blood to clot)
Plasticizers
Endothelial cells
Mast - Collagen
Thrombin
34. Drawback of micromaching
Enzyme cascade
Have to be in a clean room free of dust and biocontamination - expensive
Amide
labile cells
35. Enzymes (proteins) are not activated only when they are in contact with this type of cells
Endothelial cells
alloys - passivation
Metals
Higher
36. Activates tissue factors aka endothelial damage
cross - linking
Damage to cell membranes
alloys - passivation
Higher
37. The glass transition temperature of a poymer at which a polymer transforms from a ____ state to a ___ state.
Stress
binding
glassy to rubbery
low
38. ______ Molecular weight degrades slower than lower MW
Free Radical
labile cells
Polymers - cross linking of polymers
Higher
39. ____ are enzymes responsible for protein degradation.
Macrophages
Proteases
Protein Absorption
Lower
40. Are polymer additives used to lower glass transition temperature temperature.
Plasticizers
Polydesperity index
autologous
free radical
41. A condensation polymerization results with an ester bond between two reactants and this comes off as a result
Water
Macrophages
angiogenesis
Allogeneic
42. Type of fiber drawing that controls details of a polymer by etching on a microscopic level; thus - controlling mechanical properties as well
micromachining
Thrombin
Bioactive
Lower
43. High conductivity - isotropic - crystalline
Metals
heparin
Stress
Thrombin
44. What types of wound healing results from injury with inflammation?
Regeneration/Repair
Lower
Compression molding
Plasticizers
45. ____ is a measurement that characterizes the breadth of the distribution of a polymer's molecular weight.
Polydesperity index
Higher
scars
Intermolecular bonding - molecular weight
46. ____ is the process by which cells involved in inflammation internalize and destroy foreign material.
Phagocytosis
Stable cells
Damage to cell membranes
Regeneration/Repair
47. Is directed cell migration in response to a concentration gradient of soluble molecules.
Chemotaxis
hypoxin - angiogenesis
Allogeneic
Negative Feedback
48. _____ establishes a quantitative relationship between measured output values from an instrument and known standards of what is being measured.
negative feedback
Calibration
Stress
Thrombin
49. The fibrous capsule surrounding a permanent implant is primarily composed of ___ cells and ____ (matrix).
Mast - Collagen
Amide
Positive Feedback
Stress
50. The process of calibration establishes a quantitative relationship between ____ __ ___ _____ and the direct output of the intstrument (for example time/volume in GPC).
Have to be in a clean room free of dust and biocontamination - expensive
Compression molding
Extrusion
standards of known properties
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