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Test your basic knowledge |
Bio Engineering
Start Test
Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Mast cells release this
Lower
heparin
scars
Positive Feedback
2. Thrombin activates several upstream factors.
Number of polymers - molecular weight of polymer
Positive Feedback
cycles
Compression molding
3. Process of producing new blood vessels due to a lack on oxygen and thus inducing VEGF.
mast cells
angiogenesis
phagocytosis
Thermoplastics
4. Addition polymerization is commonly initiated by ___ - atoms that have an unpaired electron.
Chemotaxis
free radical
chemotaxis
Large
5. Cells that don't proliferate (neurons)
Permanent cells
fibrinogen - factor XIII
Negative Feedback
Thrombin
6. This cleaves into fibrinogen which creates fibrin (a sticky enzyme that allows blood to clot)
micromachining
Water
Thrombin
Proteases
7. Two things needed in the end product of the creation of a scab
Polymers - cross linking of polymers
Bioactive
Macrophages
cycles
8. Is directed cell migration in response to a concentration gradient of soluble molecules.
phagocytosis
Phagocytosis
Positive Feedback
Chemotaxis
9. Disfunction of _____ (cells) producing collagenase during the _____ phase of wound healing may form Keloid scars.
macrophages - proliferation
cross - linking
Allogeneic
binding
10. Condition in which patients can literally bleed to death.
alloys - passivation
Metals
Collagenase
Hemophilia
11. ____- are polymers that can be repeatedly softened by heating and hardened by cooling.
neutrophils - macrophages
Thermoplastics
standards of known properties
Heparin
12. During granulation stage of proliferation - growth factors that produce this ____(answer)_____ that function in degrading fibrin and replacing it with collagen.
Proteases
Have to be in a clean room free of dust and biocontamination - expensive
Damage to cell membranes
standards of known properties
13. ____ grafts are derived from the other humans.
Extrusion
Water - oxygen - metal
Allogeneic
Plasticizers
14. Foreign body giants cells are produced by fusion of ___.
cycles
Macrophages
Thrombin
Proteases
15. You're working on a square polymeric implant of 5cm length and 2mm thick. You've been asked to suggest a precise way to fabricate it - what would you suggest?
Thrombin
Compression molding
Number of polymers - molecular weight of polymer
Have to be in a clean room free of dust and biocontamination - expensive
16. ____ binds to anti- thrombin III (thrombin inhibitor) and increases its potency 1000- fold.
Allogeneic
Thrombin
Heparin
standards of known properties
17. What types of wound healing results from injury with inflammation?
micromachining
Number of polymers - molecular weight of polymer
scars
Regeneration/Repair
18. A molecular pathway in which the product of each reaction catalyzes the subsequent reaction.
Enzyme cascade
Free Radical
Thrombin
Permanent cells
19. Deformation that cannot be recovered once the load is removed from the material is ____ deformation.
phagocytosis
alloys - passivation
stress
Plastic
20. Process that makes long fibers (fiber drawing) by forcing a fluid through an oriface.
scars
phagocytosis
Permanent - replicate
Extrusion
21. Neutrophils remove bacteria/damaged cell debris from a wound site through the process of ___.
cross - linking
Large
Polydesperity index
phagocytosis
22. ____ describes the ability of a device to function appropriately in the presence of blood.
Hemocompatibility
Positive Feedback
autologous
Bioactive
23. ____ are enzymes responsible for protein degradation.
Negative Feedback
phagocytosis
Proteases
Metals
24. Enzymes (proteins) are not activated only when they are in contact with this type of cells
Hemocompatibility
cross - linking
neutrophils - macrophages
Endothelial cells
25. Polyethylene oxide grafting to biomaterials was developed to prevent coagulation by interfering with/preventing ___ ___.
Negative Feedback
Protein Absorption
phagocytosis
Amide
26. Keloid scars forms because disfuntion of
Proteases
Mast - Collagen
Collagenase
Damage to cell membranes
27. The trigger for activation of enzymes (anything but endothelial cells!)
standards of known properties
binding
Plastic
Bioactive
28. In order to produce a blood clot - thrombin cleaves/activates ____ and ____.
Metals
Plasticizers
fibrinogen - factor XIII
Heparin
29. Higher Molecular weight degrades slower than ____ MW
Water - oxygen - metal
Metals
Lower
Plastic
30. Thrombin also activates protein C-- which deactivates earlier factors in the cascade is known as ___ ___.
Calibration
Compression molding
Negative Feedback
Hemophilia
31. Enzyme that really gets the polmerization going!
Chemotaxis
Number of polymers - molecular weight of polymer
binding
Thrombin
32. List two chemical characteristics of polymers:
Bioactive
Intermolecular bonding - molecular weight
Collagenase/Remodelling
Hemocompatibility
33. Damaged cells at the site of injury (mast cells) release ___ (glycosaminoglycan).
photoactive polymers
negative feedback
heparin
Macrophages
34. Are polymer additives used to lower glass transition temperature temperature.
Plasticizers
Higher
Plastic
Negative Feedback
35. The formation of rust due to corrosion in the body is due to the reaction between these 3 things ____ - ____ - and ____ .
Polydesperity index
Collagenase
Lower
Water - oxygen - metal
36. Essentially all metallic biomaterials are ____ - comprised of two or more metals. One of these metals is selected for its ability to support _____ - the formation of a stable oxide layer that resists further corrosion.
Chemotaxis
Polydesperity index
alloys - passivation
Plastic
37. ____ is the process by which cells involved in inflammation internalize and destroy foreign material.
Proteases
Phagocytosis
macrophages - proliferation
alloys - passivation
38. A ____ implant is designed to elicit specific - intended to host responses.
Higher
Bioactive
macrophages - proliferation
Intermolecular bonding - molecular weight
39. Rather than randomly moving - moves in a directed cell migration manner for specific functions.
Positive Feedback
chemotaxis
in cytoplasm
Plasticizers
40. Cells that proliferate rapidly (fibroblasts)
mast cells
labile cells
Hemocompatibility
Water
41. Where are the tissue factors found when they're inactivated
Lower
in cytoplasm
mast cells
Water
42. Drawback of micromaching
Mast - Collagen
negative feedback
Have to be in a clean room free of dust and biocontamination - expensive
Endothelial cells
43. ______ Molecular weight degrades slower than lower MW
Higher
Polydesperity index
chemotaxis
Regeneration/Repair
44. Relative to free radical polymerization - condensation polymerization generally produces polymer of relatively ____ molecular weight.
Damage to cell membranes
low
Plasticizers
Large
45. Cells that proliferate slowly over time (aka liver)
Macrophages
Plasticizers
Stable cells
Water - oxygen - metal
46. The calculation of a polymer's molecular weight (weight average and number number average) is based upon values for ____ and ___.
Metals
Stable cells
Number of polymers - molecular weight of polymer
alloys - passivation
47. The fatigue limit is value of applied stress below which a material will not fail no matter the number of ____ applied.
neutrophils - macrophages
Collagenase
Proteases
cycles
48. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure.
angiogenesis
stress
Calibration
hypoxin - angiogenesis
49. GPC separates molecules on the basis of size by their passage over a column packed with a porous matrix. ___ molecules pass through the column more quickly.
Extrusion
Number of polymers - molecular weight of polymer
Heparin
Large
50. No healing of damage neurons is the result of ____ cells that are not able to ____.
Permanent - replicate
negative feedback
Water - oxygen - metal
photoactive polymers