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Test your basic knowledge |
Bio Engineering
Start Test
Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Activates tissue factors aka endothelial damage
micromachining
Damage to cell membranes
Enzyme cascade
neutrophils - macrophages
2. Where are the tissue factors found when they're inactivated
Compression molding
in cytoplasm
Large
low
3. You're working on a square polymeric implant of 5cm length and 2mm thick. You've been asked to suggest a precise way to fabricate it - what would you suggest?
heparin
Compression molding
free radical
Heparin
4. ____- are polymers that can be repeatedly softened by heating and hardened by cooling.
standards of known properties
in cytoplasm
Proteases
Thermoplastics
5. The two types of white blood cells:
Stable cells
Protein Absorption
neutrophils - macrophages
Polymers - cross linking of polymers
6. Collagen ____ is responsible for the gradual gain in mechanical properties of wounded tissue between roughly 4 and 52 weeks post- injury.
Intermolecular bonding - molecular weight
low
cross - linking
Regeneration/Repair
7. What types of wound healing results from injury with inflammation?
Regeneration/Repair
Phagocytosis
Bioactive
Positive Feedback
8. Are polymer additives used to lower glass transition temperature temperature.
Negative Feedback
Bioactive
Plasticizers
Positive Feedback
9. Thrombin activates several upstream factors.
Polymers - cross linking of polymers
Proteases
chemotaxis
Positive Feedback
10. Higher Molecular weight degrades slower than ____ MW
autologous
Thrombin
Lower
Phagocytosis
11. Drawback of micromaching
Have to be in a clean room free of dust and biocontamination - expensive
Polymers - cross linking of polymers
Enzyme cascade
Allogeneic
12. ______ Molecular weight degrades slower than lower MW
Hemocompatibility
Permanent - replicate
Higher
Have to be in a clean room free of dust and biocontamination - expensive
13. Disfunction of _____ (cells) producing collagenase during the _____ phase of wound healing may form Keloid scars.
scars
Phagocytosis
stress
macrophages - proliferation
14. Cardiac bypass surgery in which a vein from a patient's leg is transplanted to the patient's heart is an example of the us of ____ tissue.
Calibration
Negative Feedback
autologous
Water
15. High conductivity - isotropic - crystalline
Metals
Protein Absorption
cross - linking
alloys - passivation
16. Addition polymerization is commonly initiated by ___ - atoms that have an unpaired electron.
Heparin
Lower
Proteases
free radical
17. No healing of damage neurons is the result of ____ cells that are not able to ____.
angiogenesis
heparin
Water
Permanent - replicate
18. Neutrophils remove bacteria/damaged cell debris from a wound site through the process of ___.
Bioactive
phagocytosis
Damage to cell membranes
mast cells
19. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure
Stress
mast cells
alloys - passivation
fibrinogen - factor XIII
20. Process that makes long fibers (fiber drawing) by forcing a fluid through an oriface.
Number of polymers - molecular weight of polymer
Have to be in a clean room free of dust and biocontamination - expensive
Phagocytosis
Extrusion
21. In order to produce a blood clot - thrombin cleaves/activates ____ and ____.
chemotaxis
heparin
fibrinogen - factor XIII
Thermoplastics
22. This cleaves into fibrinogen which creates fibrin (a sticky enzyme that allows blood to clot)
Phagocytosis
Collagenase
Thrombin
Extrusion
23. Cells that don't proliferate (neurons)
Permanent cells
Free Radical
Thrombin
low
24. ____ are enzymes responsible for protein degradation.
Proteases
Permanent cells
autologous
Free Radical
25. Cells that proliferate rapidly (fibroblasts)
Extrusion
Chemotaxis
labile cells
hypoxin - angiogenesis
26. Keloid scars form due to disfunction of ____.
Regeneration/Repair
micromachining
Collagenase/Remodelling
Plasticizers
27. Essentially all metallic biomaterials are ____ - comprised of two or more metals. One of these metals is selected for its ability to support _____ - the formation of a stable oxide layer that resists further corrosion.
Damage to cell membranes
alloys - passivation
Amide
Protein Absorption
28. Classify the following polymers into appropriate families based on their bond structure i.e. the polymer is an example of poly ____.
Chemotaxis
Damage to cell membranes
Amide
Heparin
29. GPC separates molecules on the basis of size by their passage over a column packed with a porous matrix. ___ molecules pass through the column more quickly.
chemotaxis
Stable cells
Enzyme cascade
Large
30. Polyethylene oxide grafting to biomaterials was developed to prevent coagulation by interfering with/preventing ___ ___.
cross - linking
Protein Absorption
Permanent - replicate
hypoxin - angiogenesis
31. The trigger for activation of enzymes (anything but endothelial cells!)
binding
Macrophages
glassy to rubbery
Lower
32. Is directed cell migration in response to a concentration gradient of soluble molecules.
Chemotaxis
Extrusion
Compression molding
Number of polymers - molecular weight of polymer
33. Cell found in the lining of the blood vessels that release heparin and are a part of the negative feedback system.
Allogeneic
Permanent - replicate
labile cells
mast cells
34. Damaged cells at the site of injury (mast cells) release ___ (glycosaminoglycan).
heparin
angiogenesis
Collagenase
Hemocompatibility
35. Mast cells release this
Regeneration/Repair
Higher
heparin
Large
36. Condition in which patients can literally bleed to death.
Hemophilia
Positive Feedback
Extrusion
macrophages - proliferation
37. ____ describes the ability of a device to function appropriately in the presence of blood.
Large
Polydesperity index
Thermoplastics
Hemocompatibility
38. ____ is the process by which cells involved in inflammation internalize and destroy foreign material.
Phagocytosis
micromachining
scars
Compression molding
39. _____ establishes a quantitative relationship between measured output values from an instrument and known standards of what is being measured.
Proteases
Phagocytosis
Calibration
Protein Absorption
40. Process of producing new blood vessels due to a lack on oxygen and thus inducing VEGF.
Permanent - replicate
angiogenesis
Collagenase/Remodelling
Negative Feedback
41. Two things needed in the end product of the creation of a scab
Thermoplastics
Water - oxygen - metal
cycles
Polymers - cross linking of polymers
42. The calculation of a polymer's molecular weight (weight average and number number average) is based upon values for ____ and ___.
Damage to cell membranes
Thrombin
Lower
Number of polymers - molecular weight of polymer
43. The fibrous capsule surrounding a permanent implant is primarily composed of ___ cells and ____ (matrix).
neutrophils - macrophages
Mast - Collagen
labile cells
Polydesperity index
44. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure.
Have to be in a clean room free of dust and biocontamination - expensive
cross - linking
stress
scars
45. ____ binds to anti- thrombin III (thrombin inhibitor) and increases its potency 1000- fold.
Heparin
glassy to rubbery
Metals
Permanent - replicate
46. The process of calibration establishes a quantitative relationship between ____ __ ___ _____ and the direct output of the intstrument (for example time/volume in GPC).
Large
Collagenase
standards of known properties
Thrombin
47. Deformation that cannot be recovered once the load is removed from the material is ____ deformation.
Collagenase
Permanent - replicate
Thrombin
Plastic
48. The glass transition temperature of a poymer at which a polymer transforms from a ____ state to a ___ state.
glassy to rubbery
Negative Feedback
heparin
autologous
49. During granulation stage of proliferation - growth factors that produce this ____(answer)_____ that function in degrading fibrin and replacing it with collagen.
Plastic
Proteases
Phagocytosis
Compression molding
50. A ____ implant is designed to elicit specific - intended to host responses.
labile cells
Bioactive
Extrusion
Compression molding