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Test your basic knowledge |
Bio Engineering
Start Test
Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. ____ binds to anti- thrombin III (thrombin inhibitor) and increases its potency 1000- fold.
Permanent - replicate
Heparin
Collagenase
Collagenase/Remodelling
2. The fatigue limit is value of applied stress below which a material will not fail no matter the number of ____ applied.
labile cells
Endothelial cells
hypoxin - angiogenesis
cycles
3. You're working on a square polymeric implant of 5cm length and 2mm thick. You've been asked to suggest a precise way to fabricate it - what would you suggest?
Water - oxygen - metal
Compression molding
Positive Feedback
Phagocytosis
4. Polyethylene oxide grafting to biomaterials was developed to prevent coagulation by interfering with/preventing ___ ___.
Protein Absorption
in cytoplasm
Plasticizers
Water - oxygen - metal
5. Disfunction of _____ (cells) producing collagenase during the _____ phase of wound healing may form Keloid scars.
Proteases
stress
Stable cells
macrophages - proliferation
6. The process of calibration establishes a quantitative relationship between ____ __ ___ _____ and the direct output of the intstrument (for example time/volume in GPC).
standards of known properties
angiogenesis
Plasticizers
Stable cells
7. ____ is the process by which cells involved in inflammation internalize and destroy foreign material.
Intermolecular bonding - molecular weight
Phagocytosis
Thermoplastics
mast cells
8. The two types of white blood cells:
phagocytosis
neutrophils - macrophages
Water - oxygen - metal
photoactive polymers
9. Are polymer additives used to lower glass transition temperature temperature.
Permanent cells
Macrophages
glassy to rubbery
Plasticizers
10. Is directed cell migration in response to a concentration gradient of soluble molecules.
Chemotaxis
negative feedback
Polymers - cross linking of polymers
glassy to rubbery
11. The calculation of a polymer's molecular weight (weight average and number number average) is based upon values for ____ and ___.
Positive Feedback
Number of polymers - molecular weight of polymer
Thermoplastics
Intermolecular bonding - molecular weight
12. Type of fiber drawing that controls details of a polymer by etching on a microscopic level; thus - controlling mechanical properties as well
Higher
Permanent cells
micromachining
stress
13. ____ describes the ability of a device to function appropriately in the presence of blood.
angiogenesis
Hemocompatibility
Number of polymers - molecular weight of polymer
labile cells
14. High conductivity - isotropic - crystalline
Permanent cells
Negative Feedback
Metals
Positive Feedback
15. List two chemical characteristics of polymers:
Intermolecular bonding - molecular weight
Higher
Macrophages
Polydesperity index
16. GPC separates molecules on the basis of size by their passage over a column packed with a porous matrix. ___ molecules pass through the column more quickly.
Large
heparin
Lower
Stable cells
17. Thrombin activates several upstream factors.
Large
micromachining
hypoxin - angiogenesis
Positive Feedback
18. ____ grafts are derived from the other humans.
Allogeneic
autologous
hypoxin - angiogenesis
Have to be in a clean room free of dust and biocontamination - expensive
19. Activates tissue factors aka endothelial damage
free radical
Chemotaxis
micromachining
Damage to cell membranes
20. Process that makes long fibers (fiber drawing) by forcing a fluid through an oriface.
Collagenase
neutrophils - macrophages
Regeneration/Repair
Extrusion
21. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure.
Higher
low
stress
Damage to cell membranes
22. Higher Molecular weight degrades slower than ____ MW
fibrinogen - factor XIII
labile cells
Metals
Lower
23. Vascular endothelial growth factor is produced in response to ___ and stimulates ___.
Extrusion
Negative Feedback
Protein Absorption
hypoxin - angiogenesis
24. Thrombin also activates protein C-- which deactivates earlier factors in the cascade is known as ___ ___.
Thrombin
Protein Absorption
binding
Negative Feedback
25. Neutrophils remove bacteria/damaged cell debris from a wound site through the process of ___.
Calibration
Permanent cells
Plastic
phagocytosis
26. What types of wound healing results from injury with inflammation?
Large
labile cells
Regeneration/Repair
Proteases
27. Collagen ____ is responsible for the gradual gain in mechanical properties of wounded tissue between roughly 4 and 52 weeks post- injury.
neutrophils - macrophages
cross - linking
autologous
Plasticizers
28. Deformation that cannot be recovered once the load is removed from the material is ____ deformation.
micromachining
Plastic
Thrombin
Water - oxygen - metal
29. Addition polymerization is commonly initiated by ___ - atoms that have an unpaired electron.
free radical
Plastic
Permanent - replicate
labile cells
30. Process of producing new blood vessels due to a lack on oxygen and thus inducing VEGF.
angiogenesis
Allogeneic
Amide
heparin
31. Cells that proliferate slowly over time (aka liver)
in cytoplasm
Stable cells
micromachining
Thrombin
32. Cardiac bypass surgery in which a vein from a patient's leg is transplanted to the patient's heart is an example of the us of ____ tissue.
autologous
macrophages - proliferation
heparin
Allogeneic
33. Relative to free radical polymerization - condensation polymerization generally produces polymer of relatively ____ molecular weight.
low
Plasticizers
binding
heparin
34. This cleaves into fibrinogen which creates fibrin (a sticky enzyme that allows blood to clot)
Regeneration/Repair
mast cells
Thrombin
Macrophages
35. Keloid scars form due to disfunction of ____.
neutrophils - macrophages
photoactive polymers
Collagenase/Remodelling
Chemotaxis
36. This type of feedback creates
negative feedback
Thermoplastics
phagocytosis
Hemophilia
37. Foreign body giants cells are produced by fusion of ___.
Free Radical
Negative Feedback
Stable cells
Macrophages
38. The glass transition temperature of a poymer at which a polymer transforms from a ____ state to a ___ state.
neutrophils - macrophages
Protein Absorption
Water
glassy to rubbery
39. _____ establishes a quantitative relationship between measured output values from an instrument and known standards of what is being measured.
neutrophils - macrophages
Calibration
Number of polymers - molecular weight of polymer
standards of known properties
40. A condensation polymerization results with an ester bond between two reactants and this comes off as a result
Stress
Phagocytosis
Water
Free Radical
41. Condition in which patients can literally bleed to death.
Intermolecular bonding - molecular weight
Hemophilia
Plasticizers
Collagenase
42. Cell found in the lining of the blood vessels that release heparin and are a part of the negative feedback system.
mast cells
Collagenase/Remodelling
free radical
Plasticizers
43. Two things needed in the end product of the creation of a scab
Polymers - cross linking of polymers
Have to be in a clean room free of dust and biocontamination - expensive
Hemocompatibility
Stable cells
44. Cells that don't proliferate (neurons)
Thrombin
low
Permanent cells
neutrophils - macrophages
45. The formation of rust due to corrosion in the body is due to the reaction between these 3 things ____ - ____ - and ____ .
Water - oxygen - metal
Lower
negative feedback
scars
46. The trigger for activation of enzymes (anything but endothelial cells!)
Chemotaxis
scars
binding
Thrombin
47. Where are the tissue factors found when they're inactivated
in cytoplasm
Have to be in a clean room free of dust and biocontamination - expensive
Compression molding
Polymers - cross linking of polymers
48. A molecular pathway in which the product of each reaction catalyzes the subsequent reaction.
Enzyme cascade
Phagocytosis
neutrophils - macrophages
Water - oxygen - metal
49. Resulting from the build up of too much collagen at the surface of injury during the granulation tissue stage of proliferation
Water
hypoxin - angiogenesis
stress
scars
50. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure
Hemocompatibility
Stress
Number of polymers - molecular weight of polymer
Damage to cell membranes