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Test your basic knowledge |
Bio Engineering
Start Test
Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Cells that don't proliferate (neurons)
Stable cells
Amide
Permanent cells
autologous
2. GPC separates molecules on the basis of size by their passage over a column packed with a porous matrix. ___ molecules pass through the column more quickly.
Polydesperity index
Large
Protein Absorption
Thrombin
3. Vascular endothelial growth factor is produced in response to ___ and stimulates ___.
hypoxin - angiogenesis
fibrinogen - factor XIII
heparin
Allogeneic
4. Thrombin activates several upstream factors.
Positive Feedback
macrophages - proliferation
labile cells
cycles
5. Enzymes (proteins) are not activated only when they are in contact with this type of cells
binding
heparin
alloys - passivation
Endothelial cells
6. No healing of damage neurons is the result of ____ cells that are not able to ____.
scars
Permanent - replicate
Mast - Collagen
Water - oxygen - metal
7. Collagen ____ is responsible for the gradual gain in mechanical properties of wounded tissue between roughly 4 and 52 weeks post- injury.
cross - linking
Chemotaxis
angiogenesis
Thermoplastics
8. ____ describes the ability of a device to function appropriately in the presence of blood.
stress
Hemocompatibility
Lower
Bioactive
9. ____ is a measurement that characterizes the breadth of the distribution of a polymer's molecular weight.
Stress
Collagenase/Remodelling
Polydesperity index
Free Radical
10. Condition in which patients can literally bleed to death.
mast cells
Endothelial cells
Metals
Hemophilia
11. The fibrous capsule surrounding a permanent implant is primarily composed of ___ cells and ____ (matrix).
Mast - Collagen
Bioactive
low
cycles
12. Keloid scars form due to disfunction of ____.
Large
Endothelial cells
Collagenase/Remodelling
Have to be in a clean room free of dust and biocontamination - expensive
13. What types of wound healing results from injury with inflammation?
Have to be in a clean room free of dust and biocontamination - expensive
Regeneration/Repair
Macrophages
Thrombin
14. Deformation that cannot be recovered once the load is removed from the material is ____ deformation.
Hemophilia
Plastic
Negative Feedback
Protein Absorption
15. Enzyme that really gets the polmerization going!
Collagenase
Water
Lower
Thrombin
16. Drawback of micromaching
Have to be in a clean room free of dust and biocontamination - expensive
Hemocompatibility
free radical
Stress
17. The fatigue limit is value of applied stress below which a material will not fail no matter the number of ____ applied.
free radical
Hemophilia
cycles
Negative Feedback
18. Relative to free radical polymerization - condensation polymerization generally produces polymer of relatively ____ molecular weight.
low
Damage to cell membranes
glassy to rubbery
Collagenase/Remodelling
19. Activates tissue factors aka endothelial damage
hypoxin - angiogenesis
Damage to cell membranes
Extrusion
Large
20. Mast cells release this
Intermolecular bonding - molecular weight
Plasticizers
Proteases
heparin
21. List two chemical characteristics of polymers:
Intermolecular bonding - molecular weight
micromachining
Damage to cell membranes
Free Radical
22. Foreign body giants cells are produced by fusion of ___.
Negative Feedback
Macrophages
Hemocompatibility
labile cells
23. Higher Molecular weight degrades slower than ____ MW
Have to be in a clean room free of dust and biocontamination - expensive
Damage to cell membranes
Lower
Heparin
24. The two types of white blood cells:
neutrophils - macrophages
mast cells
Lower
scars
25. This type of feedback creates
Damage to cell membranes
negative feedback
Plasticizers
mast cells
26. The calculation of a polymer's molecular weight (weight average and number number average) is based upon values for ____ and ___.
Number of polymers - molecular weight of polymer
Hemophilia
Regeneration/Repair
alloys - passivation
27. Damaged cells at the site of injury (mast cells) release ___ (glycosaminoglycan).
Phagocytosis
Have to be in a clean room free of dust and biocontamination - expensive
Large
heparin
28. The trigger for activation of enzymes (anything but endothelial cells!)
micromachining
Permanent - replicate
binding
Hemocompatibility
29. A molecular pathway in which the product of each reaction catalyzes the subsequent reaction.
Thrombin
Extrusion
Enzyme cascade
Water - oxygen - metal
30. Cell found in the lining of the blood vessels that release heparin and are a part of the negative feedback system.
Polydesperity index
Thrombin
hypoxin - angiogenesis
mast cells
31. Cells that proliferate slowly over time (aka liver)
Proteases
Water
Permanent - replicate
Stable cells
32. Which of polyermization (condensation/free radical) would you choose to obtain a polymer of high molecular weight?
low
Free Radical
photoactive polymers
Polymers - cross linking of polymers
33. Keloid scars forms because disfuntion of
glassy to rubbery
Collagenase
Polydesperity index
Bioactive
34. The glass transition temperature of a poymer at which a polymer transforms from a ____ state to a ___ state.
neutrophils - macrophages
glassy to rubbery
Damage to cell membranes
Have to be in a clean room free of dust and biocontamination - expensive
35. Type of fiber drawing that controls details of a polymer by etching on a microscopic level; thus - controlling mechanical properties as well
micromachining
Mast - Collagen
binding
Heparin
36. Process that makes long fibers (fiber drawing) by forcing a fluid through an oriface.
Hemocompatibility
Heparin
Thrombin
Extrusion
37. Process of producing new blood vessels due to a lack on oxygen and thus inducing VEGF.
hypoxin - angiogenesis
angiogenesis
Have to be in a clean room free of dust and biocontamination - expensive
Hemophilia
38. Rather than randomly moving - moves in a directed cell migration manner for specific functions.
chemotaxis
alloys - passivation
scars
Protein Absorption
39. Are polymer additives used to lower glass transition temperature temperature.
Plasticizers
Stress
Water - oxygen - metal
autologous
40. What type of materials are used for photolithography? (substrate is a silicon wafer - built up material is some _____ ____ )
photoactive polymers
Polymers - cross linking of polymers
Proteases
Calibration
41. Neutrophils remove bacteria/damaged cell debris from a wound site through the process of ___.
phagocytosis
Allogeneic
Proteases
low
42. ____ are enzymes responsible for protein degradation.
chemotaxis
Allogeneic
Proteases
heparin
43. During granulation stage of proliferation - growth factors that produce this ____(answer)_____ that function in degrading fibrin and replacing it with collagen.
negative feedback
Protein Absorption
Large
Proteases
44. Is directed cell migration in response to a concentration gradient of soluble molecules.
Chemotaxis
phagocytosis
Endothelial cells
Collagenase/Remodelling
45. You're working on a square polymeric implant of 5cm length and 2mm thick. You've been asked to suggest a precise way to fabricate it - what would you suggest?
Proteases
standards of known properties
Compression molding
cross - linking
46. ____ binds to anti- thrombin III (thrombin inhibitor) and increases its potency 1000- fold.
Heparin
scars
Positive Feedback
phagocytosis
47. Cells that proliferate rapidly (fibroblasts)
phagocytosis
Polydesperity index
labile cells
Intermolecular bonding - molecular weight
48. Two things needed in the end product of the creation of a scab
Chemotaxis
scars
fibrinogen - factor XIII
Polymers - cross linking of polymers
49. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure.
stress
Mast - Collagen
Stable cells
labile cells
50. Where are the tissue factors found when they're inactivated
Metals
Proteases
in cytoplasm
autologous