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Test your basic knowledge |
Bio Engineering
Start Test
Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Disfunction of _____ (cells) producing collagenase during the _____ phase of wound healing may form Keloid scars.
Thrombin
hypoxin - angiogenesis
macrophages - proliferation
Protein Absorption
2. During granulation stage of proliferation - growth factors that produce this ____(answer)_____ that function in degrading fibrin and replacing it with collagen.
low
Proteases
standards of known properties
chemotaxis
3. Collagen ____ is responsible for the gradual gain in mechanical properties of wounded tissue between roughly 4 and 52 weeks post- injury.
Collagenase
cycles
heparin
cross - linking
4. ____ binds to anti- thrombin III (thrombin inhibitor) and increases its potency 1000- fold.
Thrombin
Heparin
Negative Feedback
binding
5. ______ Molecular weight degrades slower than lower MW
Metals
Higher
in cytoplasm
Amide
6. Where are the tissue factors found when they're inactivated
Enzyme cascade
macrophages - proliferation
in cytoplasm
alloys - passivation
7. In order to produce a blood clot - thrombin cleaves/activates ____ and ____.
Higher
Number of polymers - molecular weight of polymer
fibrinogen - factor XIII
Calibration
8. Mast cells release this
Plastic
heparin
stress
Thrombin
9. Enzymes (proteins) are not activated only when they are in contact with this type of cells
Endothelial cells
Enzyme cascade
Hemocompatibility
Proteases
10. Keloid scars forms because disfuntion of
Collagenase
Amide
Extrusion
Metals
11. GPC separates molecules on the basis of size by their passage over a column packed with a porous matrix. ___ molecules pass through the column more quickly.
macrophages - proliferation
Large
chemotaxis
low
12. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure
hypoxin - angiogenesis
Stress
free radical
Thrombin
13. Thrombin also activates protein C-- which deactivates earlier factors in the cascade is known as ___ ___.
Collagenase
Negative Feedback
Protein Absorption
Polymers - cross linking of polymers
14. Condition in which patients can literally bleed to death.
Hemophilia
Collagenase
Chemotaxis
Endothelial cells
15. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure.
micromachining
Large
stress
Plastic
16. Classify the following polymers into appropriate families based on their bond structure i.e. the polymer is an example of poly ____.
Amide
Compression molding
negative feedback
Collagenase/Remodelling
17. Higher Molecular weight degrades slower than ____ MW
Thrombin
glassy to rubbery
Lower
Collagenase/Remodelling
18. Vascular endothelial growth factor is produced in response to ___ and stimulates ___.
heparin
binding
hypoxin - angiogenesis
scars
19. Neutrophils remove bacteria/damaged cell debris from a wound site through the process of ___.
Calibration
phagocytosis
Thrombin
Amide
20. This type of feedback creates
Polydesperity index
Collagenase
negative feedback
in cytoplasm
21. Cardiac bypass surgery in which a vein from a patient's leg is transplanted to the patient's heart is an example of the us of ____ tissue.
Phagocytosis
autologous
chemotaxis
Plastic
22. Cells that proliferate slowly over time (aka liver)
Bioactive
Water
Hemophilia
Stable cells
23. Cells that proliferate rapidly (fibroblasts)
Bioactive
Positive Feedback
labile cells
Thrombin
24. Activates tissue factors aka endothelial damage
binding
Collagenase
Compression molding
Damage to cell membranes
25. Thrombin activates several upstream factors.
Higher
Polymers - cross linking of polymers
Hemocompatibility
Positive Feedback
26. ____ is a measurement that characterizes the breadth of the distribution of a polymer's molecular weight.
Polydesperity index
Metals
Thermoplastics
Extrusion
27. ____ grafts are derived from the other humans.
Allogeneic
chemotaxis
stress
Compression molding
28. The process of calibration establishes a quantitative relationship between ____ __ ___ _____ and the direct output of the intstrument (for example time/volume in GPC).
cycles
Large
Extrusion
standards of known properties
29. Is directed cell migration in response to a concentration gradient of soluble molecules.
Heparin
Chemotaxis
Stable cells
Water
30. A ____ implant is designed to elicit specific - intended to host responses.
Bioactive
heparin
in cytoplasm
phagocytosis
31. Type of fiber drawing that controls details of a polymer by etching on a microscopic level; thus - controlling mechanical properties as well
Compression molding
Regeneration/Repair
Extrusion
micromachining
32. The fatigue limit is value of applied stress below which a material will not fail no matter the number of ____ applied.
Extrusion
cycles
heparin
Allogeneic
33. A molecular pathway in which the product of each reaction catalyzes the subsequent reaction.
Large
Proteases
Collagenase
Enzyme cascade
34. _____ establishes a quantitative relationship between measured output values from an instrument and known standards of what is being measured.
Proteases
Stable cells
cross - linking
Calibration
35. Resulting from the build up of too much collagen at the surface of injury during the granulation tissue stage of proliferation
scars
Number of polymers - molecular weight of polymer
Enzyme cascade
Free Radical
36. List two chemical characteristics of polymers:
Intermolecular bonding - molecular weight
standards of known properties
Endothelial cells
Enzyme cascade
37. ____ are enzymes responsible for protein degradation.
Collagenase
Proteases
Chemotaxis
Stable cells
38. Addition polymerization is commonly initiated by ___ - atoms that have an unpaired electron.
phagocytosis
mast cells
Collagenase/Remodelling
free radical
39. The glass transition temperature of a poymer at which a polymer transforms from a ____ state to a ___ state.
macrophages - proliferation
glassy to rubbery
Mast - Collagen
Lower
40. Relative to free radical polymerization - condensation polymerization generally produces polymer of relatively ____ molecular weight.
Thrombin
Heparin
free radical
low
41. The formation of rust due to corrosion in the body is due to the reaction between these 3 things ____ - ____ - and ____ .
Higher
Water - oxygen - metal
Have to be in a clean room free of dust and biocontamination - expensive
Negative Feedback
42. The fibrous capsule surrounding a permanent implant is primarily composed of ___ cells and ____ (matrix).
heparin
chemotaxis
stress
Mast - Collagen
43. Foreign body giants cells are produced by fusion of ___.
Macrophages
Regeneration/Repair
Higher
cycles
44. Cells that don't proliferate (neurons)
Have to be in a clean room free of dust and biocontamination - expensive
Higher
Stress
Permanent cells
45. Drawback of micromaching
hypoxin - angiogenesis
Endothelial cells
Have to be in a clean room free of dust and biocontamination - expensive
phagocytosis
46. Process of producing new blood vessels due to a lack on oxygen and thus inducing VEGF.
Hemocompatibility
Have to be in a clean room free of dust and biocontamination - expensive
angiogenesis
low
47. This cleaves into fibrinogen which creates fibrin (a sticky enzyme that allows blood to clot)
low
Polymers - cross linking of polymers
Thrombin
cycles
48. Keloid scars form due to disfunction of ____.
Calibration
Collagenase/Remodelling
Permanent cells
Lower
49. Enzyme that really gets the polmerization going!
Thrombin
micromachining
Hemocompatibility
stress
50. What type of materials are used for photolithography? (substrate is a silicon wafer - built up material is some _____ ____ )
Hemocompatibility
photoactive polymers
binding
Permanent - replicate