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Bio Engineering
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Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Drawback of micromaching
Chemotaxis
Have to be in a clean room free of dust and biocontamination - expensive
Allogeneic
fibrinogen - factor XIII
2. The fatigue limit is value of applied stress below which a material will not fail no matter the number of ____ applied.
cycles
Hemocompatibility
low
autologous
3. Keloid scars forms because disfuntion of
Collagenase
phagocytosis
Intermolecular bonding - molecular weight
Polydesperity index
4. Deformation that cannot be recovered once the load is removed from the material is ____ deformation.
Chemotaxis
autologous
Plastic
Positive Feedback
5. Are polymer additives used to lower glass transition temperature temperature.
chemotaxis
Plasticizers
Regeneration/Repair
Proteases
6. ____ are enzymes responsible for protein degradation.
Proteases
Higher
Negative Feedback
Collagenase
7. Process of producing new blood vessels due to a lack on oxygen and thus inducing VEGF.
Bioactive
angiogenesis
Lower
heparin
8. The calculation of a polymer's molecular weight (weight average and number number average) is based upon values for ____ and ___.
mast cells
Number of polymers - molecular weight of polymer
heparin
Plastic
9. Addition polymerization is commonly initiated by ___ - atoms that have an unpaired electron.
Proteases
Compression molding
free radical
Chemotaxis
10. Where are the tissue factors found when they're inactivated
Collagenase/Remodelling
in cytoplasm
stress
scars
11. Cells that don't proliferate (neurons)
Stress
Permanent cells
Chemotaxis
heparin
12. Condition in which patients can literally bleed to death.
micromachining
Polydesperity index
Hemophilia
Free Radical
13. ____ is the process by which cells involved in inflammation internalize and destroy foreign material.
Endothelial cells
Damage to cell membranes
Calibration
Phagocytosis
14. _____ establishes a quantitative relationship between measured output values from an instrument and known standards of what is being measured.
mast cells
heparin
Mast - Collagen
Calibration
15. Disfunction of _____ (cells) producing collagenase during the _____ phase of wound healing may form Keloid scars.
low
macrophages - proliferation
autologous
Thermoplastics
16. Keloid scars form due to disfunction of ____.
Positive Feedback
Hemophilia
Collagenase/Remodelling
Intermolecular bonding - molecular weight
17. Type of fiber drawing that controls details of a polymer by etching on a microscopic level; thus - controlling mechanical properties as well
Proteases
Number of polymers - molecular weight of polymer
micromachining
Large
18. You're working on a square polymeric implant of 5cm length and 2mm thick. You've been asked to suggest a precise way to fabricate it - what would you suggest?
macrophages - proliferation
Permanent - replicate
negative feedback
Compression molding
19. List two chemical characteristics of polymers:
Positive Feedback
Compression molding
Plastic
Intermolecular bonding - molecular weight
20. ____ grafts are derived from the other humans.
free radical
Stable cells
Allogeneic
neutrophils - macrophages
21. Relative to free radical polymerization - condensation polymerization generally produces polymer of relatively ____ molecular weight.
hypoxin - angiogenesis
mast cells
Heparin
low
22. Higher Molecular weight degrades slower than ____ MW
Macrophages
angiogenesis
Lower
hypoxin - angiogenesis
23. Which of polyermization (condensation/free radical) would you choose to obtain a polymer of high molecular weight?
Free Radical
angiogenesis
Bioactive
Thermoplastics
24. Foreign body giants cells are produced by fusion of ___.
Collagenase
Metals
labile cells
Macrophages
25. Two things needed in the end product of the creation of a scab
Phagocytosis
Negative Feedback
Damage to cell membranes
Polymers - cross linking of polymers
26. Enzyme that really gets the polmerization going!
heparin
low
Allogeneic
Thrombin
27. Mast cells release this
Protein Absorption
Calibration
Hemocompatibility
heparin
28. A ____ implant is designed to elicit specific - intended to host responses.
Bioactive
Intermolecular bonding - molecular weight
Thrombin
macrophages - proliferation
29. Polyethylene oxide grafting to biomaterials was developed to prevent coagulation by interfering with/preventing ___ ___.
Mast - Collagen
glassy to rubbery
Protein Absorption
chemotaxis
30. Rather than randomly moving - moves in a directed cell migration manner for specific functions.
heparin
Damage to cell membranes
autologous
chemotaxis
31. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure
heparin
Hemophilia
Stress
Heparin
32. Enzymes (proteins) are not activated only when they are in contact with this type of cells
phagocytosis
Endothelial cells
Permanent cells
negative feedback
33. This type of feedback creates
Free Radical
negative feedback
Polymers - cross linking of polymers
binding
34. Cardiac bypass surgery in which a vein from a patient's leg is transplanted to the patient's heart is an example of the us of ____ tissue.
neutrophils - macrophages
autologous
micromachining
Number of polymers - molecular weight of polymer
35. The fibrous capsule surrounding a permanent implant is primarily composed of ___ cells and ____ (matrix).
Permanent cells
Mast - Collagen
Water
Metals
36. Resulting from the build up of too much collagen at the surface of injury during the granulation tissue stage of proliferation
chemotaxis
mast cells
Regeneration/Repair
scars
37. High conductivity - isotropic - crystalline
Hemophilia
phagocytosis
Chemotaxis
Metals
38. Is directed cell migration in response to a concentration gradient of soluble molecules.
labile cells
Negative Feedback
Chemotaxis
Permanent - replicate
39. Activates tissue factors aka endothelial damage
heparin
Negative Feedback
Damage to cell membranes
Polydesperity index
40. The two types of white blood cells:
neutrophils - macrophages
Positive Feedback
Chemotaxis
mast cells
41. Essentially all metallic biomaterials are ____ - comprised of two or more metals. One of these metals is selected for its ability to support _____ - the formation of a stable oxide layer that resists further corrosion.
Collagenase/Remodelling
Chemotaxis
alloys - passivation
Have to be in a clean room free of dust and biocontamination - expensive
42. No healing of damage neurons is the result of ____ cells that are not able to ____.
macrophages - proliferation
Permanent - replicate
heparin
cross - linking
43. The glass transition temperature of a poymer at which a polymer transforms from a ____ state to a ___ state.
Thermoplastics
angiogenesis
glassy to rubbery
Macrophages
44. ____ describes the ability of a device to function appropriately in the presence of blood.
Hemocompatibility
chemotaxis
angiogenesis
fibrinogen - factor XIII
45. This cleaves into fibrinogen which creates fibrin (a sticky enzyme that allows blood to clot)
Phagocytosis
Large
Thrombin
Proteases
46. A condensation polymerization results with an ester bond between two reactants and this comes off as a result
Thermoplastics
Water
angiogenesis
Plasticizers
47. Cells that proliferate slowly over time (aka liver)
Negative Feedback
Thrombin
Stable cells
cycles
48. Cell found in the lining of the blood vessels that release heparin and are a part of the negative feedback system.
Negative Feedback
Calibration
Hemophilia
mast cells
49. Thrombin activates several upstream factors.
Number of polymers - molecular weight of polymer
Positive Feedback
Damage to cell membranes
Compression molding
50. ____- are polymers that can be repeatedly softened by heating and hardened by cooling.
Thermoplastics
Number of polymers - molecular weight of polymer
Hemophilia
Water
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