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Bio Engineering
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Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure.
Allogeneic
scars
in cytoplasm
stress
2. The fibrous capsule surrounding a permanent implant is primarily composed of ___ cells and ____ (matrix).
Intermolecular bonding - molecular weight
autologous
Polymers - cross linking of polymers
Mast - Collagen
3. Where are the tissue factors found when they're inactivated
Damage to cell membranes
Compression molding
in cytoplasm
free radical
4. _____ establishes a quantitative relationship between measured output values from an instrument and known standards of what is being measured.
Amide
fibrinogen - factor XIII
Calibration
Regeneration/Repair
5. Process that makes long fibers (fiber drawing) by forcing a fluid through an oriface.
Thermoplastics
Metals
Extrusion
Intermolecular bonding - molecular weight
6. The formation of rust due to corrosion in the body is due to the reaction between these 3 things ____ - ____ - and ____ .
Hemocompatibility
Allogeneic
Positive Feedback
Water - oxygen - metal
7. Condition in which patients can literally bleed to death.
neutrophils - macrophages
Hemophilia
free radical
Positive Feedback
8. GPC separates molecules on the basis of size by their passage over a column packed with a porous matrix. ___ molecules pass through the column more quickly.
stress
Enzyme cascade
mast cells
Large
9. Thrombin also activates protein C-- which deactivates earlier factors in the cascade is known as ___ ___.
Plastic
stress
Negative Feedback
Higher
10. Mast cells release this
Bioactive
heparin
Proteases
Extrusion
11. List two chemical characteristics of polymers:
heparin
Intermolecular bonding - molecular weight
micromachining
angiogenesis
12. Foreign body giants cells are produced by fusion of ___.
Polymers - cross linking of polymers
Polydesperity index
Metals
Macrophages
13. Classify the following polymers into appropriate families based on their bond structure i.e. the polymer is an example of poly ____.
labile cells
Amide
angiogenesis
neutrophils - macrophages
14. High conductivity - isotropic - crystalline
labile cells
scars
autologous
Metals
15. Cells that don't proliferate (neurons)
standards of known properties
Permanent cells
Bioactive
Water
16. Enzyme that really gets the polmerization going!
Thrombin
Chemotaxis
Phagocytosis
cross - linking
17. ____ is the process by which cells involved in inflammation internalize and destroy foreign material.
Phagocytosis
Lower
stress
Negative Feedback
18. Higher Molecular weight degrades slower than ____ MW
stress
Lower
Permanent cells
cycles
19. Deformation that cannot be recovered once the load is removed from the material is ____ deformation.
fibrinogen - factor XIII
Thrombin
micromachining
Plastic
20. Cardiac bypass surgery in which a vein from a patient's leg is transplanted to the patient's heart is an example of the us of ____ tissue.
binding
Enzyme cascade
Collagenase
autologous
21. Activates tissue factors aka endothelial damage
Hemocompatibility
mast cells
Bioactive
Damage to cell membranes
22. The fatigue limit is value of applied stress below which a material will not fail no matter the number of ____ applied.
stress
photoactive polymers
cycles
Stress
23. This cleaves into fibrinogen which creates fibrin (a sticky enzyme that allows blood to clot)
Free Radical
Thrombin
Plastic
photoactive polymers
24. ______ Molecular weight degrades slower than lower MW
Permanent - replicate
Proteases
Higher
in cytoplasm
25. Enzymes (proteins) are not activated only when they are in contact with this type of cells
Endothelial cells
labile cells
Water
negative feedback
26. A condensation polymerization results with an ester bond between two reactants and this comes off as a result
photoactive polymers
Bioactive
Water
Protein Absorption
27. The calculation of a polymer's molecular weight (weight average and number number average) is based upon values for ____ and ___.
Number of polymers - molecular weight of polymer
neutrophils - macrophages
Heparin
Extrusion
28. Which of polyermization (condensation/free radical) would you choose to obtain a polymer of high molecular weight?
Protein Absorption
Free Radical
Heparin
scars
29. What types of wound healing results from injury with inflammation?
Thermoplastics
Regeneration/Repair
angiogenesis
Hemophilia
30. Collagen ____ is responsible for the gradual gain in mechanical properties of wounded tissue between roughly 4 and 52 weeks post- injury.
cross - linking
Proteases
binding
Stable cells
31. Cells that proliferate slowly over time (aka liver)
Damage to cell membranes
Stable cells
Bioactive
Collagenase/Remodelling
32. No healing of damage neurons is the result of ____ cells that are not able to ____.
Stable cells
autologous
Permanent - replicate
Thrombin
33. Addition polymerization is commonly initiated by ___ - atoms that have an unpaired electron.
heparin
Hemophilia
free radical
Protein Absorption
34. Keloid scars forms because disfuntion of
Protein Absorption
Collagenase
mast cells
Plasticizers
35. A ____ implant is designed to elicit specific - intended to host responses.
Enzyme cascade
Permanent cells
Positive Feedback
Bioactive
36. Rather than randomly moving - moves in a directed cell migration manner for specific functions.
hypoxin - angiogenesis
chemotaxis
Hemophilia
angiogenesis
37. Type of fiber drawing that controls details of a polymer by etching on a microscopic level; thus - controlling mechanical properties as well
cycles
Free Radical
micromachining
Negative Feedback
38. Are polymer additives used to lower glass transition temperature temperature.
Plasticizers
Free Radical
Collagenase
Calibration
39. The two types of white blood cells:
Heparin
neutrophils - macrophages
negative feedback
Have to be in a clean room free of dust and biocontamination - expensive
40. Thrombin activates several upstream factors.
alloys - passivation
Positive Feedback
Number of polymers - molecular weight of polymer
Protein Absorption
41. Neutrophils remove bacteria/damaged cell debris from a wound site through the process of ___.
Positive Feedback
Hemophilia
phagocytosis
Thrombin
42. ____- are polymers that can be repeatedly softened by heating and hardened by cooling.
Macrophages
Water
Thermoplastics
cycles
43. What type of materials are used for photolithography? (substrate is a silicon wafer - built up material is some _____ ____ )
fibrinogen - factor XIII
Polymers - cross linking of polymers
photoactive polymers
stress
44. Cell found in the lining of the blood vessels that release heparin and are a part of the negative feedback system.
in cytoplasm
phagocytosis
standards of known properties
mast cells
45. The trigger for activation of enzymes (anything but endothelial cells!)
binding
Chemotaxis
phagocytosis
Collagenase
46. Polyethylene oxide grafting to biomaterials was developed to prevent coagulation by interfering with/preventing ___ ___.
Protein Absorption
Extrusion
Intermolecular bonding - molecular weight
Hemocompatibility
47. Relative to free radical polymerization - condensation polymerization generally produces polymer of relatively ____ molecular weight.
binding
fibrinogen - factor XIII
Proteases
low
48. Drawback of micromaching
phagocytosis
Higher
Have to be in a clean room free of dust and biocontamination - expensive
Plasticizers
49. The glass transition temperature of a poymer at which a polymer transforms from a ____ state to a ___ state.
Phagocytosis
glassy to rubbery
Hemocompatibility
Water - oxygen - metal
50. You're working on a square polymeric implant of 5cm length and 2mm thick. You've been asked to suggest a precise way to fabricate it - what would you suggest?
Thermoplastics
photoactive polymers
Compression molding
fibrinogen - factor XIII
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