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Test your basic knowledge |
Bio Engineering
Start Test
Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. You're working on a square polymeric implant of 5cm length and 2mm thick. You've been asked to suggest a precise way to fabricate it - what would you suggest?
heparin
Damage to cell membranes
Endothelial cells
Compression molding
2. Damaged cells at the site of injury (mast cells) release ___ (glycosaminoglycan).
Permanent - replicate
heparin
Allogeneic
Number of polymers - molecular weight of polymer
3. A ____ implant is designed to elicit specific - intended to host responses.
Calibration
Macrophages
alloys - passivation
Bioactive
4. In order to produce a blood clot - thrombin cleaves/activates ____ and ____.
Polymers - cross linking of polymers
Plasticizers
fibrinogen - factor XIII
hypoxin - angiogenesis
5. Enzymes (proteins) are not activated only when they are in contact with this type of cells
Water - oxygen - metal
Metals
Thrombin
Endothelial cells
6. Process of producing new blood vessels due to a lack on oxygen and thus inducing VEGF.
Protein Absorption
angiogenesis
Phagocytosis
Amide
7. Type of fiber drawing that controls details of a polymer by etching on a microscopic level; thus - controlling mechanical properties as well
micromachining
Hemocompatibility
Enzyme cascade
Endothelial cells
8. High conductivity - isotropic - crystalline
free radical
Polydesperity index
Metals
Proteases
9. ____ binds to anti- thrombin III (thrombin inhibitor) and increases its potency 1000- fold.
Chemotaxis
Water - oxygen - metal
Higher
Heparin
10. Keloid scars forms because disfuntion of
Collagenase
mast cells
Stable cells
Large
11. GPC separates molecules on the basis of size by their passage over a column packed with a porous matrix. ___ molecules pass through the column more quickly.
cycles
Large
Phagocytosis
in cytoplasm
12. Resulting from the build up of too much collagen at the surface of injury during the granulation tissue stage of proliferation
heparin
Large
photoactive polymers
scars
13. The two types of white blood cells:
Thermoplastics
Plastic
neutrophils - macrophages
photoactive polymers
14. Process that makes long fibers (fiber drawing) by forcing a fluid through an oriface.
Extrusion
cycles
Proteases
Thrombin
15. ____ is the process by which cells involved in inflammation internalize and destroy foreign material.
low
Phagocytosis
Heparin
micromachining
16. Are polymer additives used to lower glass transition temperature temperature.
Thermoplastics
Have to be in a clean room free of dust and biocontamination - expensive
Plasticizers
Enzyme cascade
17. ____ describes the ability of a device to function appropriately in the presence of blood.
Bioactive
Hemocompatibility
Phagocytosis
Stable cells
18. This cleaves into fibrinogen which creates fibrin (a sticky enzyme that allows blood to clot)
Thrombin
Allogeneic
scars
Polymers - cross linking of polymers
19. What type of materials are used for photolithography? (substrate is a silicon wafer - built up material is some _____ ____ )
photoactive polymers
Compression molding
Water - oxygen - metal
Polydesperity index
20. Polyethylene oxide grafting to biomaterials was developed to prevent coagulation by interfering with/preventing ___ ___.
heparin
Protein Absorption
mast cells
Plastic
21. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure
Plasticizers
Stress
Extrusion
Endothelial cells
22. Collagen ____ is responsible for the gradual gain in mechanical properties of wounded tissue between roughly 4 and 52 weeks post- injury.
cross - linking
autologous
labile cells
Collagenase/Remodelling
23. Thrombin also activates protein C-- which deactivates earlier factors in the cascade is known as ___ ___.
Negative Feedback
Protein Absorption
Water - oxygen - metal
autologous
24. ____ grafts are derived from the other humans.
Thrombin
negative feedback
Allogeneic
Endothelial cells
25. Disfunction of _____ (cells) producing collagenase during the _____ phase of wound healing may form Keloid scars.
labile cells
Stable cells
Chemotaxis
macrophages - proliferation
26. A molecular pathway in which the product of each reaction catalyzes the subsequent reaction.
Enzyme cascade
Negative Feedback
Lower
phagocytosis
27. Cells that don't proliferate (neurons)
Positive Feedback
Thrombin
Proteases
Permanent cells
28. This type of feedback creates
negative feedback
Bioactive
Thermoplastics
Lower
29. Condition in which patients can literally bleed to death.
Stable cells
Amide
scars
Hemophilia
30. Cardiac bypass surgery in which a vein from a patient's leg is transplanted to the patient's heart is an example of the us of ____ tissue.
autologous
phagocytosis
free radical
Regeneration/Repair
31. _____ establishes a quantitative relationship between measured output values from an instrument and known standards of what is being measured.
cycles
glassy to rubbery
Calibration
Macrophages
32. Where are the tissue factors found when they're inactivated
Phagocytosis
in cytoplasm
Proteases
standards of known properties
33. The fatigue limit is value of applied stress below which a material will not fail no matter the number of ____ applied.
Stress
Mast - Collagen
Bioactive
cycles
34. The trigger for activation of enzymes (anything but endothelial cells!)
binding
standards of known properties
cycles
Intermolecular bonding - molecular weight
35. Thrombin activates several upstream factors.
Phagocytosis
Positive Feedback
low
Bioactive
36. Cells that proliferate slowly over time (aka liver)
Thermoplastics
binding
autologous
Stable cells
37. Classify the following polymers into appropriate families based on their bond structure i.e. the polymer is an example of poly ____.
heparin
Heparin
heparin
Amide
38. Two things needed in the end product of the creation of a scab
Thermoplastics
labile cells
heparin
Polymers - cross linking of polymers
39. Neutrophils remove bacteria/damaged cell debris from a wound site through the process of ___.
phagocytosis
cycles
mast cells
Mast - Collagen
40. Cells that proliferate rapidly (fibroblasts)
photoactive polymers
Plastic
Stable cells
labile cells
41. Deformation that cannot be recovered once the load is removed from the material is ____ deformation.
labile cells
Plastic
Water
Chemotaxis
42. The formation of rust due to corrosion in the body is due to the reaction between these 3 things ____ - ____ - and ____ .
photoactive polymers
Water - oxygen - metal
Mast - Collagen
Stress
43. ____ are enzymes responsible for protein degradation.
Bioactive
Proteases
labile cells
stress
44. The fibrous capsule surrounding a permanent implant is primarily composed of ___ cells and ____ (matrix).
labile cells
Mast - Collagen
standards of known properties
Damage to cell membranes
45. List two chemical characteristics of polymers:
scars
photoactive polymers
Intermolecular bonding - molecular weight
in cytoplasm
46. Foreign body giants cells are produced by fusion of ___.
Macrophages
Collagenase
Bioactive
neutrophils - macrophages
47. The process of calibration establishes a quantitative relationship between ____ __ ___ _____ and the direct output of the intstrument (for example time/volume in GPC).
Free Radical
Regeneration/Repair
standards of known properties
photoactive polymers
48. The glass transition temperature of a poymer at which a polymer transforms from a ____ state to a ___ state.
Water
glassy to rubbery
angiogenesis
micromachining
49. During granulation stage of proliferation - growth factors that produce this ____(answer)_____ that function in degrading fibrin and replacing it with collagen.
free radical
macrophages - proliferation
Higher
Proteases
50. Keloid scars form due to disfunction of ____.
Proteases
Collagenase/Remodelling
Polymers - cross linking of polymers
Protein Absorption