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Test your basic knowledge |
Bio Engineering
Start Test
Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. The formation of rust due to corrosion in the body is due to the reaction between these 3 things ____ - ____ - and ____ .
Intermolecular bonding - molecular weight
heparin
Water - oxygen - metal
stress
2. Enzymes (proteins) are not activated only when they are in contact with this type of cells
Macrophages
Stress
Endothelial cells
glassy to rubbery
3. Process of producing new blood vessels due to a lack on oxygen and thus inducing VEGF.
angiogenesis
Chemotaxis
Macrophages
macrophages - proliferation
4. ____ binds to anti- thrombin III (thrombin inhibitor) and increases its potency 1000- fold.
cross - linking
Heparin
labile cells
Extrusion
5. ____- are polymers that can be repeatedly softened by heating and hardened by cooling.
Thermoplastics
Large
macrophages - proliferation
free radical
6. The trigger for activation of enzymes (anything but endothelial cells!)
binding
Calibration
Proteases
Phagocytosis
7. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure.
stress
Negative Feedback
Collagenase/Remodelling
Enzyme cascade
8. Cardiac bypass surgery in which a vein from a patient's leg is transplanted to the patient's heart is an example of the us of ____ tissue.
Mast - Collagen
autologous
hypoxin - angiogenesis
Polydesperity index
9. Two things needed in the end product of the creation of a scab
Protein Absorption
Polymers - cross linking of polymers
Lower
Calibration
10. Collagen ____ is responsible for the gradual gain in mechanical properties of wounded tissue between roughly 4 and 52 weeks post- injury.
cross - linking
Regeneration/Repair
stress
Number of polymers - molecular weight of polymer
11. The process of calibration establishes a quantitative relationship between ____ __ ___ _____ and the direct output of the intstrument (for example time/volume in GPC).
standards of known properties
angiogenesis
Proteases
in cytoplasm
12. The fibrous capsule surrounding a permanent implant is primarily composed of ___ cells and ____ (matrix).
Proteases
Allogeneic
Mast - Collagen
binding
13. Cells that don't proliferate (neurons)
Intermolecular bonding - molecular weight
hypoxin - angiogenesis
Permanent cells
Collagenase/Remodelling
14. A molecular pathway in which the product of each reaction catalyzes the subsequent reaction.
Large
Enzyme cascade
Higher
neutrophils - macrophages
15. Thrombin also activates protein C-- which deactivates earlier factors in the cascade is known as ___ ___.
binding
Water
Amide
Negative Feedback
16. ______ Molecular weight degrades slower than lower MW
Intermolecular bonding - molecular weight
Metals
phagocytosis
Higher
17. A ____ implant is designed to elicit specific - intended to host responses.
Bioactive
chemotaxis
alloys - passivation
Water - oxygen - metal
18. Activates tissue factors aka endothelial damage
Bioactive
Large
Damage to cell membranes
Enzyme cascade
19. Deformation that cannot be recovered once the load is removed from the material is ____ deformation.
Plastic
free radical
heparin
Higher
20. Is directed cell migration in response to a concentration gradient of soluble molecules.
Endothelial cells
Free Radical
Chemotaxis
labile cells
21. The glass transition temperature of a poymer at which a polymer transforms from a ____ state to a ___ state.
glassy to rubbery
Have to be in a clean room free of dust and biocontamination - expensive
Polymers - cross linking of polymers
Thrombin
22. ____ grafts are derived from the other humans.
Phagocytosis
Heparin
scars
Allogeneic
23. Process that makes long fibers (fiber drawing) by forcing a fluid through an oriface.
micromachining
Extrusion
in cytoplasm
Stress
24. Thrombin activates several upstream factors.
Positive Feedback
fibrinogen - factor XIII
binding
micromachining
25. ____ is the process by which cells involved in inflammation internalize and destroy foreign material.
Phagocytosis
Plasticizers
Thrombin
Negative Feedback
26. This cleaves into fibrinogen which creates fibrin (a sticky enzyme that allows blood to clot)
chemotaxis
Compression molding
Plastic
Thrombin
27. Rather than randomly moving - moves in a directed cell migration manner for specific functions.
heparin
Heparin
chemotaxis
standards of known properties
28. The calculation of a polymer's molecular weight (weight average and number number average) is based upon values for ____ and ___.
Water
Number of polymers - molecular weight of polymer
Collagenase
standards of known properties
29. GPC separates molecules on the basis of size by their passage over a column packed with a porous matrix. ___ molecules pass through the column more quickly.
autologous
Damage to cell membranes
Plasticizers
Large
30. Higher Molecular weight degrades slower than ____ MW
Lower
Permanent - replicate
Extrusion
glassy to rubbery
31. Foreign body giants cells are produced by fusion of ___.
glassy to rubbery
Macrophages
Number of polymers - molecular weight of polymer
Plasticizers
32. Classify the following polymers into appropriate families based on their bond structure i.e. the polymer is an example of poly ____.
Compression molding
Amide
Chemotaxis
Hemophilia
33. ____ are enzymes responsible for protein degradation.
Macrophages
Stable cells
Proteases
glassy to rubbery
34. The fatigue limit is value of applied stress below which a material will not fail no matter the number of ____ applied.
Plasticizers
cycles
Endothelial cells
Hemocompatibility
35. You're working on a square polymeric implant of 5cm length and 2mm thick. You've been asked to suggest a precise way to fabricate it - what would you suggest?
Have to be in a clean room free of dust and biocontamination - expensive
Stress
Stable cells
Compression molding
36. High conductivity - isotropic - crystalline
chemotaxis
fibrinogen - factor XIII
Metals
standards of known properties
37. Condition in which patients can literally bleed to death.
Hemophilia
Extrusion
Permanent - replicate
cross - linking
38. Damaged cells at the site of injury (mast cells) release ___ (glycosaminoglycan).
in cytoplasm
micromachining
scars
heparin
39. Where are the tissue factors found when they're inactivated
Phagocytosis
Compression molding
neutrophils - macrophages
in cytoplasm
40. Cells that proliferate slowly over time (aka liver)
Water - oxygen - metal
Stable cells
Chemotaxis
angiogenesis
41. What type of materials are used for photolithography? (substrate is a silicon wafer - built up material is some _____ ____ )
Endothelial cells
photoactive polymers
low
Extrusion
42. Resulting from the build up of too much collagen at the surface of injury during the granulation tissue stage of proliferation
phagocytosis
low
scars
Thermoplastics
43. Cells that proliferate rapidly (fibroblasts)
labile cells
Calibration
Permanent cells
negative feedback
44. Are polymer additives used to lower glass transition temperature temperature.
Water
heparin
Plasticizers
low
45. Type of fiber drawing that controls details of a polymer by etching on a microscopic level; thus - controlling mechanical properties as well
Large
micromachining
Plastic
Positive Feedback
46. No healing of damage neurons is the result of ____ cells that are not able to ____.
Allogeneic
Thermoplastics
Free Radical
Permanent - replicate
47. Mast cells release this
micromachining
heparin
Regeneration/Repair
Free Radical
48. Which of polyermization (condensation/free radical) would you choose to obtain a polymer of high molecular weight?
Free Radical
mast cells
Thermoplastics
Large
49. List two chemical characteristics of polymers:
Intermolecular bonding - molecular weight
Polymers - cross linking of polymers
Number of polymers - molecular weight of polymer
Phagocytosis
50. ____ describes the ability of a device to function appropriately in the presence of blood.
low
Bioactive
Hemocompatibility
Macrophages
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