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Test your basic knowledge |
Bio Engineering
Start Test
Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. A molecular pathway in which the product of each reaction catalyzes the subsequent reaction.
macrophages - proliferation
Enzyme cascade
fibrinogen - factor XIII
alloys - passivation
2. Foreign body giants cells are produced by fusion of ___.
micromachining
Macrophages
Negative Feedback
Collagenase
3. _____ establishes a quantitative relationship between measured output values from an instrument and known standards of what is being measured.
Positive Feedback
Polymers - cross linking of polymers
Calibration
chemotaxis
4. ____ is a measurement that characterizes the breadth of the distribution of a polymer's molecular weight.
Large
heparin
mast cells
Polydesperity index
5. The process of calibration establishes a quantitative relationship between ____ __ ___ _____ and the direct output of the intstrument (for example time/volume in GPC).
stress
Chemotaxis
Thrombin
standards of known properties
6. Activates tissue factors aka endothelial damage
Thrombin
alloys - passivation
free radical
Damage to cell membranes
7. Classify the following polymers into appropriate families based on their bond structure i.e. the polymer is an example of poly ____.
Amide
Collagenase
labile cells
micromachining
8. ____ grafts are derived from the other humans.
Polydesperity index
Allogeneic
Macrophages
neutrophils - macrophages
9. During granulation stage of proliferation - growth factors that produce this ____(answer)_____ that function in degrading fibrin and replacing it with collagen.
glassy to rubbery
Large
Chemotaxis
Proteases
10. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure.
Collagenase
stress
micromachining
Lower
11. The two types of white blood cells:
Calibration
Water - oxygen - metal
neutrophils - macrophages
Extrusion
12. Relative to free radical polymerization - condensation polymerization generally produces polymer of relatively ____ molecular weight.
standards of known properties
low
Chemotaxis
Plasticizers
13. Keloid scars form due to disfunction of ____.
Have to be in a clean room free of dust and biocontamination - expensive
Collagenase/Remodelling
micromachining
neutrophils - macrophages
14. Higher Molecular weight degrades slower than ____ MW
chemotaxis
Lower
standards of known properties
Collagenase/Remodelling
15. This type of feedback creates
cycles
negative feedback
glassy to rubbery
Hemocompatibility
16. Polyethylene oxide grafting to biomaterials was developed to prevent coagulation by interfering with/preventing ___ ___.
Protein Absorption
Polydesperity index
Polymers - cross linking of polymers
glassy to rubbery
17. The fibrous capsule surrounding a permanent implant is primarily composed of ___ cells and ____ (matrix).
Mast - Collagen
photoactive polymers
Bioactive
Number of polymers - molecular weight of polymer
18. Vascular endothelial growth factor is produced in response to ___ and stimulates ___.
Collagenase
Intermolecular bonding - molecular weight
hypoxin - angiogenesis
Plasticizers
19. Thrombin activates several upstream factors.
alloys - passivation
Permanent - replicate
cycles
Positive Feedback
20. List two chemical characteristics of polymers:
macrophages - proliferation
Enzyme cascade
Intermolecular bonding - molecular weight
Polymers - cross linking of polymers
21. Which of polyermization (condensation/free radical) would you choose to obtain a polymer of high molecular weight?
Intermolecular bonding - molecular weight
Free Radical
micromachining
Hemocompatibility
22. This cleaves into fibrinogen which creates fibrin (a sticky enzyme that allows blood to clot)
Metals
Thrombin
Heparin
cross - linking
23. Keloid scars forms because disfuntion of
Collagenase
photoactive polymers
Thrombin
Have to be in a clean room free of dust and biocontamination - expensive
24. No healing of damage neurons is the result of ____ cells that are not able to ____.
Damage to cell membranes
negative feedback
Permanent - replicate
scars
25. Essentially all metallic biomaterials are ____ - comprised of two or more metals. One of these metals is selected for its ability to support _____ - the formation of a stable oxide layer that resists further corrosion.
Collagenase/Remodelling
Metals
alloys - passivation
Positive Feedback
26. A ____ implant is designed to elicit specific - intended to host responses.
Mast - Collagen
Hemophilia
standards of known properties
Bioactive
27. Thrombin also activates protein C-- which deactivates earlier factors in the cascade is known as ___ ___.
Metals
Hemocompatibility
Negative Feedback
Plasticizers
28. Cell found in the lining of the blood vessels that release heparin and are a part of the negative feedback system.
Polydesperity index
mast cells
Permanent cells
Proteases
29. Disfunction of _____ (cells) producing collagenase during the _____ phase of wound healing may form Keloid scars.
Negative Feedback
Thermoplastics
Stress
macrophages - proliferation
30. ____- are polymers that can be repeatedly softened by heating and hardened by cooling.
Endothelial cells
micromachining
cycles
Thermoplastics
31. A condensation polymerization results with an ester bond between two reactants and this comes off as a result
Free Radical
hypoxin - angiogenesis
Water
cycles
32. Condition in which patients can literally bleed to death.
free radical
Amide
Hemophilia
standards of known properties
33. Deformation that cannot be recovered once the load is removed from the material is ____ deformation.
Mast - Collagen
Plastic
heparin
Large
34. Neutrophils remove bacteria/damaged cell debris from a wound site through the process of ___.
scars
phagocytosis
Proteases
Collagenase/Remodelling
35. Are polymer additives used to lower glass transition temperature temperature.
free radical
Chemotaxis
Thrombin
Plasticizers
36. Addition polymerization is commonly initiated by ___ - atoms that have an unpaired electron.
glassy to rubbery
Extrusion
Stress
free radical
37. The trigger for activation of enzymes (anything but endothelial cells!)
Lower
Damage to cell membranes
binding
Large
38. Cardiac bypass surgery in which a vein from a patient's leg is transplanted to the patient's heart is an example of the us of ____ tissue.
standards of known properties
autologous
Have to be in a clean room free of dust and biocontamination - expensive
Macrophages
39. The calculation of a polymer's molecular weight (weight average and number number average) is based upon values for ____ and ___.
Stress
photoactive polymers
Number of polymers - molecular weight of polymer
Thermoplastics
40. What types of wound healing results from injury with inflammation?
Regeneration/Repair
Hemophilia
fibrinogen - factor XIII
Negative Feedback
41. The glass transition temperature of a poymer at which a polymer transforms from a ____ state to a ___ state.
Thermoplastics
glassy to rubbery
Heparin
Allogeneic
42. Process of producing new blood vessels due to a lack on oxygen and thus inducing VEGF.
Stable cells
Number of polymers - molecular weight of polymer
heparin
angiogenesis
43. Enzymes (proteins) are not activated only when they are in contact with this type of cells
Proteases
Endothelial cells
Proteases
Polymers - cross linking of polymers
44. ____ describes the ability of a device to function appropriately in the presence of blood.
Hemocompatibility
neutrophils - macrophages
Higher
Calibration
45. Rather than randomly moving - moves in a directed cell migration manner for specific functions.
Extrusion
Enzyme cascade
Endothelial cells
chemotaxis
46. You're working on a square polymeric implant of 5cm length and 2mm thick. You've been asked to suggest a precise way to fabricate it - what would you suggest?
Mast - Collagen
Compression molding
angiogenesis
micromachining
47. Drawback of micromaching
micromachining
Permanent - replicate
in cytoplasm
Have to be in a clean room free of dust and biocontamination - expensive
48. Is directed cell migration in response to a concentration gradient of soluble molecules.
Chemotaxis
Thermoplastics
hypoxin - angiogenesis
Extrusion
49. Damaged cells at the site of injury (mast cells) release ___ (glycosaminoglycan).
Permanent cells
Collagenase/Remodelling
heparin
fibrinogen - factor XIII
50. The fatigue limit is value of applied stress below which a material will not fail no matter the number of ____ applied.
cycles
fibrinogen - factor XIII
Number of polymers - molecular weight of polymer
micromachining