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Test your basic knowledge |
Bio Engineering
Start Test
Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. ______ Molecular weight degrades slower than lower MW
Damage to cell membranes
Higher
Compression molding
heparin
2. The glass transition temperature of a poymer at which a polymer transforms from a ____ state to a ___ state.
standards of known properties
glassy to rubbery
heparin
Enzyme cascade
3. Rather than randomly moving - moves in a directed cell migration manner for specific functions.
chemotaxis
mast cells
Permanent cells
Regeneration/Repair
4. The fatigue limit is the ___ below which the material can withstand an infinite number of cycles without failure.
stress
heparin
standards of known properties
Proteases
5. ____ describes the ability of a device to function appropriately in the presence of blood.
Hemocompatibility
Collagenase/Remodelling
binding
Extrusion
6. During granulation stage of proliferation - growth factors that produce this ____(answer)_____ that function in degrading fibrin and replacing it with collagen.
standards of known properties
Metals
Proteases
Polydesperity index
7. The process of calibration establishes a quantitative relationship between ____ __ ___ _____ and the direct output of the intstrument (for example time/volume in GPC).
standards of known properties
Enzyme cascade
Number of polymers - molecular weight of polymer
Heparin
8. This type of feedback creates
glassy to rubbery
Allogeneic
negative feedback
Chemotaxis
9. Resulting from the build up of too much collagen at the surface of injury during the granulation tissue stage of proliferation
micromachining
scars
chemotaxis
stress
10. ____ are enzymes responsible for protein degradation.
Macrophages
Proteases
Stress
Permanent - replicate
11. ____ binds to anti- thrombin III (thrombin inhibitor) and increases its potency 1000- fold.
Heparin
Chemotaxis
Metals
Number of polymers - molecular weight of polymer
12. Thrombin also activates protein C-- which deactivates earlier factors in the cascade is known as ___ ___.
Permanent - replicate
fibrinogen - factor XIII
Plastic
Negative Feedback
13. Essentially all metallic biomaterials are ____ - comprised of two or more metals. One of these metals is selected for its ability to support _____ - the formation of a stable oxide layer that resists further corrosion.
macrophages - proliferation
photoactive polymers
alloys - passivation
negative feedback
14. Classify the following polymers into appropriate families based on their bond structure i.e. the polymer is an example of poly ____.
Mast - Collagen
binding
Amide
glassy to rubbery
15. Type of fiber drawing that controls details of a polymer by etching on a microscopic level; thus - controlling mechanical properties as well
Proteases
Permanent cells
micromachining
Compression molding
16. Damaged cells at the site of injury (mast cells) release ___ (glycosaminoglycan).
Proteases
chemotaxis
heparin
labile cells
17. The fibrous capsule surrounding a permanent implant is primarily composed of ___ cells and ____ (matrix).
Lower
in cytoplasm
Amide
Mast - Collagen
18. ____ is a measurement that characterizes the breadth of the distribution of a polymer's molecular weight.
Polydesperity index
angiogenesis
Polymers - cross linking of polymers
in cytoplasm
19. Process that makes long fibers (fiber drawing) by forcing a fluid through an oriface.
Have to be in a clean room free of dust and biocontamination - expensive
Calibration
Extrusion
Number of polymers - molecular weight of polymer
20. Deformation that cannot be recovered once the load is removed from the material is ____ deformation.
chemotaxis
neutrophils - macrophages
Plastic
Thrombin
21. Cells that proliferate slowly over time (aka liver)
Stable cells
Lower
micromachining
Metals
22. Keloid scars forms because disfuntion of
Heparin
Collagenase
Hemocompatibility
Water - oxygen - metal
23. The fatigue limit is value of applied stress below which a material will not fail no matter the number of ____ applied.
Macrophages
heparin
Number of polymers - molecular weight of polymer
cycles
24. The trigger for activation of enzymes (anything but endothelial cells!)
Water - oxygen - metal
stress
Bioactive
binding
25. A condensation polymerization results with an ester bond between two reactants and this comes off as a result
Phagocytosis
Mast - Collagen
Thrombin
Water
26. Process of producing new blood vessels due to a lack on oxygen and thus inducing VEGF.
Number of polymers - molecular weight of polymer
Compression molding
angiogenesis
Have to be in a clean room free of dust and biocontamination - expensive
27. Activates tissue factors aka endothelial damage
Hemocompatibility
cycles
Positive Feedback
Damage to cell membranes
28. Cells that don't proliferate (neurons)
Compression molding
Permanent cells
Permanent - replicate
Damage to cell membranes
29. Cell found in the lining of the blood vessels that release heparin and are a part of the negative feedback system.
mast cells
micromachining
Extrusion
Water - oxygen - metal
30. A ____ implant is designed to elicit specific - intended to host responses.
Higher
Bioactive
Chemotaxis
Large
31. _____ establishes a quantitative relationship between measured output values from an instrument and known standards of what is being measured.
Permanent - replicate
Plastic
Protein Absorption
Calibration
32. Cells that proliferate rapidly (fibroblasts)
phagocytosis
in cytoplasm
labile cells
binding
33. Higher Molecular weight degrades slower than ____ MW
Heparin
Lower
Calibration
Have to be in a clean room free of dust and biocontamination - expensive
34. Foreign body giants cells are produced by fusion of ___.
macrophages - proliferation
Phagocytosis
heparin
Macrophages
35. The formation of rust due to corrosion in the body is due to the reaction between these 3 things ____ - ____ - and ____ .
Free Radical
Water - oxygen - metal
Water
alloys - passivation
36. ____ is the process by which cells involved in inflammation internalize and destroy foreign material.
Phagocytosis
stress
Permanent cells
heparin
37. Which of polyermization (condensation/free radical) would you choose to obtain a polymer of high molecular weight?
Free Radical
Damage to cell membranes
Plastic
cycles
38. Collagen ____ is responsible for the gradual gain in mechanical properties of wounded tissue between roughly 4 and 52 weeks post- injury.
Lower
Large
Chemotaxis
cross - linking
39. Thrombin activates several upstream factors.
Thrombin
micromachining
Positive Feedback
Number of polymers - molecular weight of polymer
40. Addition polymerization is commonly initiated by ___ - atoms that have an unpaired electron.
Water
free radical
Metals
Plastic
41. ____ grafts are derived from the other humans.
Allogeneic
Stress
Thermoplastics
Enzyme cascade
42. Vascular endothelial growth factor is produced in response to ___ and stimulates ___.
hypoxin - angiogenesis
Extrusion
cycles
Lower
43. The two types of white blood cells:
Chemotaxis
neutrophils - macrophages
labile cells
autologous
44. GPC separates molecules on the basis of size by their passage over a column packed with a porous matrix. ___ molecules pass through the column more quickly.
Water - oxygen - metal
Large
Permanent cells
neutrophils - macrophages
45. High conductivity - isotropic - crystalline
Polydesperity index
Negative Feedback
Metals
Bioactive
46. This cleaves into fibrinogen which creates fibrin (a sticky enzyme that allows blood to clot)
Thrombin
Enzyme cascade
macrophages - proliferation
Number of polymers - molecular weight of polymer
47. Relative to free radical polymerization - condensation polymerization generally produces polymer of relatively ____ molecular weight.
low
standards of known properties
Free Radical
Intermolecular bonding - molecular weight
48. ____- are polymers that can be repeatedly softened by heating and hardened by cooling.
Chemotaxis
Protein Absorption
autologous
Thermoplastics
49. Condition in which patients can literally bleed to death.
Hemophilia
Stress
Polymers - cross linking of polymers
Hemocompatibility
50. Drawback of micromaching
Free Radical
Permanent - replicate
Thermoplastics
Have to be in a clean room free of dust and biocontamination - expensive