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Test your basic knowledge |
Bio Engineering
Start Test
Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Are polymer additives used to lower glass transition temperature temperature.
heparin
Plasticizers
Thrombin
Stable cells
2. Classify the following polymers into appropriate families based on their bond structure i.e. the polymer is an example of poly ____.
cross - linking
fibrinogen - factor XIII
Amide
Hemophilia
3. The fatigue limit is value of applied stress below which a material will not fail no matter the number of ____ applied.
cycles
Endothelial cells
Regeneration/Repair
Metals
4. Drawback of micromaching
Intermolecular bonding - molecular weight
Have to be in a clean room free of dust and biocontamination - expensive
low
angiogenesis
5. Mast cells release this
Bioactive
Extrusion
Stable cells
heparin
6. Collagen ____ is responsible for the gradual gain in mechanical properties of wounded tissue between roughly 4 and 52 weeks post- injury.
Chemotaxis
mast cells
Negative Feedback
cross - linking
7. This type of feedback creates
phagocytosis
binding
neutrophils - macrophages
negative feedback
8. Process that makes long fibers (fiber drawing) by forcing a fluid through an oriface.
negative feedback
in cytoplasm
Extrusion
Bioactive
9. Enzyme that really gets the polmerization going!
Thermoplastics
Thrombin
Proteases
Phagocytosis
10. Cells that proliferate rapidly (fibroblasts)
Hemophilia
labile cells
micromachining
Collagenase/Remodelling
11. ____ binds to anti- thrombin III (thrombin inhibitor) and increases its potency 1000- fold.
Heparin
alloys - passivation
mast cells
free radical
12. ____ is the process by which cells involved in inflammation internalize and destroy foreign material.
Large
Phagocytosis
Polydesperity index
Proteases
13. The glass transition temperature of a poymer at which a polymer transforms from a ____ state to a ___ state.
phagocytosis
glassy to rubbery
Water - oxygen - metal
heparin
14. Activates tissue factors aka endothelial damage
Collagenase
Damage to cell membranes
stress
chemotaxis
15. The two types of white blood cells:
micromachining
autologous
neutrophils - macrophages
Metals
16. The trigger for activation of enzymes (anything but endothelial cells!)
binding
alloys - passivation
Polymers - cross linking of polymers
Plastic
17. Process of producing new blood vessels due to a lack on oxygen and thus inducing VEGF.
Stress
Collagenase/Remodelling
angiogenesis
Polydesperity index
18. Cardiac bypass surgery in which a vein from a patient's leg is transplanted to the patient's heart is an example of the us of ____ tissue.
free radical
Phagocytosis
in cytoplasm
autologous
19. Thrombin also activates protein C-- which deactivates earlier factors in the cascade is known as ___ ___.
fibrinogen - factor XIII
cycles
Negative Feedback
alloys - passivation
20. In order to produce a blood clot - thrombin cleaves/activates ____ and ____.
Water
Chemotaxis
fibrinogen - factor XIII
Heparin
21. ____ describes the ability of a device to function appropriately in the presence of blood.
macrophages - proliferation
Regeneration/Repair
hypoxin - angiogenesis
Hemocompatibility
22. What types of wound healing results from injury with inflammation?
Regeneration/Repair
Enzyme cascade
Damage to cell membranes
Hemocompatibility
23. Two things needed in the end product of the creation of a scab
Polymers - cross linking of polymers
micromachining
hypoxin - angiogenesis
Intermolecular bonding - molecular weight
24. Type of fiber drawing that controls details of a polymer by etching on a microscopic level; thus - controlling mechanical properties as well
labile cells
micromachining
Collagenase
Have to be in a clean room free of dust and biocontamination - expensive
25. Keloid scars form due to disfunction of ____.
Collagenase/Remodelling
phagocytosis
Higher
free radical
26. The formation of rust due to corrosion in the body is due to the reaction between these 3 things ____ - ____ - and ____ .
Proteases
cycles
Metals
Water - oxygen - metal
27. Thrombin activates several upstream factors.
macrophages - proliferation
fibrinogen - factor XIII
labile cells
Positive Feedback
28. ____ is a measurement that characterizes the breadth of the distribution of a polymer's molecular weight.
fibrinogen - factor XIII
Polydesperity index
Positive Feedback
Amide
29. This cleaves into fibrinogen which creates fibrin (a sticky enzyme that allows blood to clot)
binding
Endothelial cells
Negative Feedback
Thrombin
30. Resulting from the build up of too much collagen at the surface of injury during the granulation tissue stage of proliferation
scars
Proteases
Lower
fibrinogen - factor XIII
31. GPC separates molecules on the basis of size by their passage over a column packed with a porous matrix. ___ molecules pass through the column more quickly.
Thrombin
Large
Amide
Positive Feedback
32. Condition in which patients can literally bleed to death.
Hemophilia
Have to be in a clean room free of dust and biocontamination - expensive
Permanent - replicate
Mast - Collagen
33. Which of polyermization (condensation/free radical) would you choose to obtain a polymer of high molecular weight?
cycles
Free Radical
Enzyme cascade
Permanent - replicate
34. Is directed cell migration in response to a concentration gradient of soluble molecules.
Hemocompatibility
cross - linking
Chemotaxis
heparin
35. The process of calibration establishes a quantitative relationship between ____ __ ___ _____ and the direct output of the intstrument (for example time/volume in GPC).
Heparin
Intermolecular bonding - molecular weight
Polymers - cross linking of polymers
standards of known properties
36. What type of materials are used for photolithography? (substrate is a silicon wafer - built up material is some _____ ____ )
Macrophages
Polydesperity index
Collagenase/Remodelling
photoactive polymers
37. ____- are polymers that can be repeatedly softened by heating and hardened by cooling.
Intermolecular bonding - molecular weight
Stable cells
Thermoplastics
Higher
38. ____ are enzymes responsible for protein degradation.
Proteases
glassy to rubbery
Permanent - replicate
stress
39. Rather than randomly moving - moves in a directed cell migration manner for specific functions.
chemotaxis
Proteases
Damage to cell membranes
Collagenase/Remodelling
40. Enzymes (proteins) are not activated only when they are in contact with this type of cells
Endothelial cells
Hemophilia
Stress
Have to be in a clean room free of dust and biocontamination - expensive
41. The fibrous capsule surrounding a permanent implant is primarily composed of ___ cells and ____ (matrix).
Macrophages
Mast - Collagen
micromachining
labile cells
42. A condensation polymerization results with an ester bond between two reactants and this comes off as a result
mast cells
scars
Extrusion
Water
43. A ____ implant is designed to elicit specific - intended to host responses.
Water - oxygen - metal
Extrusion
Macrophages
Bioactive
44. Essentially all metallic biomaterials are ____ - comprised of two or more metals. One of these metals is selected for its ability to support _____ - the formation of a stable oxide layer that resists further corrosion.
Hemocompatibility
alloys - passivation
Phagocytosis
Allogeneic
45. Cells that proliferate slowly over time (aka liver)
hypoxin - angiogenesis
Stable cells
Proteases
heparin
46. A molecular pathway in which the product of each reaction catalyzes the subsequent reaction.
stress
Enzyme cascade
angiogenesis
mast cells
47. No healing of damage neurons is the result of ____ cells that are not able to ____.
Permanent - replicate
negative feedback
cross - linking
Proteases
48. Disfunction of _____ (cells) producing collagenase during the _____ phase of wound healing may form Keloid scars.
macrophages - proliferation
chemotaxis
cycles
Stable cells
49. Higher Molecular weight degrades slower than ____ MW
glassy to rubbery
Stable cells
Extrusion
Lower
50. _____ establishes a quantitative relationship between measured output values from an instrument and known standards of what is being measured.
micromachining
Calibration
Proteases
free radical