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Biochemistry

Instructions:
  • Answer 50 questions in 15 minutes.
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  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What is the function of Zinc






2. What is pleiotropy and given an example






3. Which aspect of the spliceosome do patients with lupus make antibodies against






4. What happens in vit D def






5. What is the RDE of de novo purine synthesis






6. What is the activated carrier for phosphoryl






7. What two pathways is carbomoyl phosphate involved in - and what enzyme deficiency leads to a build of carbamoyl phosphate leading to what element in pyrimidine synthesis






8. congenital deficiency of homogentisic acid oxidase in the degradative pathway of tyrosine to fumarate leading to dark connective tissue - brown pigmented sclera - urine turns black on standing - dz and worst complication






9. What form of amino acids are found in proteins






10. What substances are uncouling agents






11. Which enzyme involved in RNA synthesis does not require a template






12. Type IV BM






13. What happens in vit D excess






14. What sugar is sorbitol converted to and via what enzyme - and What can happen in cells lacking this enzyme






15. What step of uric acid synthesis does xanthine oxidase catalyze






16. What is the physiologic role of dystrophin






17. Type IV collagen






18. What is the source of energy in the fasting state between meals






19. What substance in egg whites binds biotin






20. When does aspartate enter the urea cycle






21. In eukaryotes - What does RNA poly II make






22. recurrent pulmonary infxns in CF are due to what organisms






23. What substances induce phosphofructokinase






24. What are covalent alterations






25. What enzyme results in classic galactosemia and What is the clinical






26. What does PURe As Gold and CUT The Py stand for






27. What substance inside the cell serves to oxidize glutatione






28. What is the amino acid precursor for histamine






29. In what direction are DNA and RNA synthesized

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30. Acetyl - CoA carboxylase catalyzes what rxn






31. Gene imprinting implies that How many alleles are active at a single locus






32. Of the four possible fates for pyruvate - which one carries amino groups to liver from muscle






33. What lab technique is use to profile gene expression levels of thousands of genes simultaneously to study certain diseases and treatments






34. What produces NADPH






35. Where are the secretory proteins made and N- linked oligosaccharide addtions put on proteins






36. What does a pyruvate dehydrogenase deficiency lead to and What are the findings






37. characterize x linked recessive






38. What are the findings in PKU






39. cell signaling defect of fibroblast growth factor (FGF) receptor 3 - results in dwarfism - short limbs - head/trunk nl size - associated with advanced paternal age






40. What creates the musty body odor in PKU






41. What CETP do






42. What is the TX for CF and What does it do






43. Where is vit B12 found






44. What is dominant negative mutation and give an example






45. What initiates protein synthesis






46. What enzymes metabolize fatty acids and amino acids






47. What regulates whether FBPase -2 or PFK-2 is active






48. How doe NADH electrons from glycolysis and the TCA cycle enter the mitochondiria






49. Milder form of type I with nl blood lactate levels - dz and enzyme

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50. What does the golgi assemble proteoglycans from