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Biochemistry

Instructions:
  • Answer 50 questions in 15 minutes.
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  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What does apoE do






2. What does the primary transcript combine with to form the spliceosome






3. What is axonemal dynein






4. Wgat substances directly inhibit mitochondrial ATPase - causing an inc in proton gradient - no ATP because pump is stopped






5. What step of uric acid synthesis does xanthine oxidase catalyze






6. What are the findings in Down's syndrome






7. What kind of RNA is transported out of the nucleus






8. Which enzyme involved in RNA synthesis does not require a template






9. ADPKD is associated with What additional conditions






10. What are the results of pancreatic insuff in CF






11. caf






12. Where is EtOH dehydrogenase located






13. energy malnutrition resulting in tissues and muscle wasting - loss of subQ fat - variable edema






14. What is Gowers maneuver






15. What is the name is fxn of vit B3






16. Which cells are rich in smooth ER






17. What are the complications/signs of familial hypercholesterolemia






18. What are the purely ketogenic amino acids






19. What does a phosphatase do






20. Which antihelminthe drugs work on microtubules






21. What is the rate determining enzyme (RDE) of glycolysis






22. What happens in elongation of protein synthesis

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23. In which structures do you find microtubules






24. What does hormone sensitive lipase do






25. How do microtubules grow and collapse






26. Mediates reverse cholesterol transport from periphery to liver - acts as respository for apoC an apoE - secreted from both liver and small intestine






27. Of the four possible fates for pyruvate - which one is a transition from glycolysis to TCA cycle






28. What is loss of heterozygosity and give an example






29. decreases In what substances can cause PKU






30. What is the hardy weinberg allele prevalence






31. What two proteins make up microtubules and how are they arranged






32. What is the activated carrier for Co2






33. elevated LDL due to defective or absent LDL receptor - heterozygotes have cholesterol ~300 - homozygotes ~700






34. What is the rate limiting enzyme in cholesterol synthesis






35. What are uncoupling agents






36. What are pyrimidines made from






37. peripheral neuropathy - developmental delay - optic atrophy - glopoid cells






38. Patients with chronic granulomatous disease are at increased risk of infection From which kind of organisms






39. In the chromatin structure - which histones form the octamer - and which ties the nucleosome beads together in a string?






40. Which carbon bears the triphosphate and the energy source for bond formation

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41. What does PURe As Gold and CUT The Py stand for






42. What are the findings in Lesch - Nyhan






43. What is the composition of urea and where do each part derive from






44. What does DNA ligase do






45. This is the site where negative regulators bind






46. What does the vimentin stain for






47. What are the results of unbalanced translocation






48. CF - is AR deletion In what gene On what chromosome resulting in a deletion inf what?






49. FAP is due to deletion On what gene On what chromosome






50. depression - progressive dementia - choreiform movements - caudate atrophy and dec levels of GABA and ACH in the brain