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Biochemistry

Instructions:
  • Answer 50 questions in 15 minutes.
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  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What is dominant negative mutation and give an example






2. Which end of the tRNA is the amino acid bound to...






3. Where is fructose 1 -6 bisphosphatase found and What does it do






4. What are the characteristics of angelmans syndrome and How does it occur






5. What is the treatment for cystathionine synthase def






6. What converts dopamine to NE






7. Where are FADH2 electrons transferred to...






8. Where is vit A found in the diet






9. What chromosome is the NF gene on...






10. What are the 2 distinct phases of the HMP shunt and How many ATP are used and produced






11. What is RNAi used for






12. Where are cytosolic and organellar proteins made






13. In which state is FBPase -2 active






14. What is the target of the 3' hydroxyl attack






15. In a marathon Where does energy come from






16. What does the golgi do to sugars in proteoglycans and of selected tyrosine on proteins






17. In eukaryotes - What does RNA poly III make






18. I g fat = ? Kcal






19. If two alleles are present - but the active allele is deleted - what happens






20. Of the four possible fates for pyruvate - which one can replenish TCA cycle or be used in gluconeogenesis






21. Type I bone






22. What does lactase deficiency cause






23. What defects characterize DiGeorge syndrome






24. Why is albinism inheritnace varialbe due to...






25. How does OTC def present






26. This is the site where negative regulators bind






27. What reaction does adenosine deaminase normally catalyze






28. nucleotide repeat for fragile x






29. Why can't even chain fatty acids produce new glucose






30. What inhibits pyruvate kinase






31. What is the energy source in the fed state right after a meal






32. phosphorylation of glucose to yield glucose 6 phosphate serves as the 1st step of what rxns and what enzymes catalyze it






33. Fluorescent DNA or RNA probe binds to specific gene of interest - used for specific localization of genes and direct visualization of anomalies - like microdeletions - at molecular level






34. Giving folate during early pregnancy is important to prevent what birth defects






35. When are glycogen reserves depleted






36. What is the result of vit B5 def






37. What are ketone bodies made from - where are they metabolized and how are they excreted






38. Which tumor suppresors inhibit G1 to S progression - where mutations result in unrestrained growth






39. What is sorbitol - how and why is it made






40. The pyruvate dehydrogenase complex serves In what reaction: products






41. central and peripheral demyelination with ataxia and dementia






42. What is Gowers maneuver






43. CF - is AR deletion In what gene On what chromosome resulting in a deletion inf what?






44. What causes Hartnup's disease






45. bilateral - massive enlargement of of kidneys due to multiple large cysts






46. What causes maple syrup urine disease and What does it lead to...






47. What is incomplete penetrence and give an example






48. What is a frame shift






49. cytoskeletal elements associated with vimenentin - desmin - cytokeratin - glial fibrillary acid protiens (GFAP) - neurofilaments






50. What is proteasomal degredation