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Biochemistry

Instructions:
  • Answer 50 questions in 15 minutes.
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  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Name as many x- linked recessive disorders as you can

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2. Describe robertsonian translocation






3. What does a mischarge tRNA do






4. What is the energy source for translocation






5. What is the source of energy in the fasting state between meals






6. What apolipoprotiens are on VLDL






7. FAP is due to deletion On what gene On what chromosome






8. Patients with chronic granulomatous disease are at increased risk of infection From which kind of organisms






9. How many ATP are created by aerobic metobolism of glucose in muslce via what shuttle






10. What does desmin stain for






11. In which single strand DNA repair mechanism do specific endonucleases release the oligonucTIDE containing bases and DNA poly and ligase fill and reseal - and what disease occures when this is mutated






12. What two pathways is carbomoyl phosphate involved in - and what enzyme deficiency leads to a build of carbamoyl phosphate leading to what element in pyrimidine synthesis






13. What is NADPH used for






14. What causes B12 def






15. What is the activated carrier for phosphoryl






16. What is the TX for pyruvate dehydrogenase deficiency






17. What is kartageners syndrome






18. Milder form of type I with nl blood lactate levels - dz and enzyme

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19. What does a northern blot use as its sample






20. What is a missense mutation






21. What does fomepizole do






22. What is the RDE of gluconeogenesis






23. What is NADPH's role inside RBCs






24. Wgat substances directly inhibit mitochondrial ATPase - causing an inc in proton gradient - no ATP because pump is stopped






25. Describe the pathophys of the aorta in a pt with marfans - and the eyes






26. What does GFAP stain for






27. Of the four possible fates for pyruvate - which one can replenish TCA cycle or be used in gluconeogenesis






28. How does patients present with ADPKD






29. Which enzyme involved in RNA synthesis does not require a template






30. What co - factors are required for the pyruvated dehydrogenase complex






31. Which antifungal drugs work on microtubules






32. What are the products for glycolysis






33. What does NADPH oxidase deficiency result in and why






34. Where do you find elastin and What does it do






35. Synthesis of vit B3 requires what other vitamin






36. What is the hardy weinber heterozygote prevalence






37. Which RNA poly opens DNA at promotor site






38. What is the energy source for tRNA actication (charging)






39. What are cyclin - CDK complexes






40. metaphse chromosomes are stained - ordered and numbered according to morphology - size - arm length ratio - banding pattern






41. What initiates protein synthesis






42. Adenosine deaminase deficiency is an important cause of what immunodeficiency?






43. What is the amino acid precuror for creatine - urea and nitric oxide






44. characterize autosomal recessive inheritance






45. peripheral neuropathy - developmental delay - optic atrophy - glopoid cells






46. What is the RDE of ketogenesis






47. central and peripheral demyelination with ataxia and dementia






48. What causes biotin def






49. How are the many staggered tropocollagen molecules reinforced






50. What are the 3 AR forms of homocystinuria