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Biochemistry

Instructions:
  • Answer 50 questions in 15 minutes.
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  • Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What does biotin def cause






2. pyruvate carboxylase catalyzes what rxn






3. What are uncoupling agents






4. what findings are associated with marfans






5. What happens in vit B2 def






6. elevated LDL due to defective or absent LDL receptor - heterozygotes have cholesterol ~300 - homozygotes ~700






7. What apolipoprotiens are on VLDL






8. Severe fasting hypoglycemia - inc glycogen storage in liver - inc blood lactate - hepatomegaly - dz and def enzyme






9. What is the RDE of TCA cycle






10. What is incomplete penetrence and give an example






11. What bone disorder has x linked dominant inheritance






12. What is the energy source in the fed state right after a meal






13. characterize x linked recessive






14. Infection with what organism can cause B12 def






15. What are the mRNA stop codons






16. How is ATP used by the cell






17. What other complex is similar to the pyruvate dehydrogenase complex in that it has the same co - factors and generates succinyl - CoA






18. Which carbon bears the triphosphate and the energy source for bond formation

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19. congenital microdeletion of long arm of chromosoe 7 with findings of elfin facies - mental retardation - hypercalcemia - well developed verbal skills - extreme friendliness with strangers - cardiovascular problems






20. What is regeneration of methionine depedent on...






21. For eukaryotes - Where does replication begin?






22. What metabolic rxns occur in the mitochondria






23. What happens in elongation of protein synthesis

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24. What is loss of heterozygosity and give an example






25. What happens in termination of proteins synthesis






26. What happens with dry beriberi






27. Where are cytosolic and organellar proteins made






28. What is mosaicism and give an example






29. cytoskeletal elements in micorvilli - muscle contracting fibers - cytokenesis - adherens jxns






30. What enzyme becomes essential in PKU






31. What enzyme results in classic galactosemia and What is the clinical






32. What is the Name and fxn of vit B5






33. What happens in carnitine def






34. What does the primary transcript combine with to form the spliceosome






35. What 3 amino acids are necessary for purine synthesis






36. How do tetracyclines work






37. delivers hepatic TGs to peripheral tissue - secreted by liver






38. CF - is AR deletion In what gene On what chromosome resulting in a deletion inf what?






39. Name as many x- linked recessive disorders as you can

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40. What order kinetics does EtOH dehydrogenase have






41. What is the function of biotin






42. What causes Hartnup's disease






43. What substances induce phosphofructokinase






44. How does warfarin work






45. What does aminoacyl tRNA synthetase do the AA before and after it binds to tRNA - and what happens if it's the wrong the match






46. What are bite cells and when do you see them






47. How is Lesch Neyhan inherited






48. congenital deficiency of homogentisic acid oxidase in the degradative pathway of tyrosine to fumarate leading to dark connective tissue - brown pigmented sclera - urine turns black on standing - dz and worst complication






49. What does the golgi assemble proteoglycans from






50. What enzyme degrades a small amount of glycogen in lysosomes







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