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Biochemistry

Instructions:
  • Answer 50 questions in 15 minutes.
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  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What are cyclins






2. What is the origin of replication






3. What is the trinucleotide repeat in fragile X






4. What makes up a nucleoside






5. What do the single stranded binding proteins do






6. What substance in egg whites binds biotin






7. What leads to the deletion of the dystrophin gene in duchenne's muscular dystrophy






8. What does the mutation in the gene cause in protein synthesis






9. What test is used for B12 def






10. Where are the secretory proteins made and N- linked oligosaccharide addtions put on proteins






11. Which kind of osteogenesis imperfecta is fata in utero or in neonatal period






12. Of the four possible fates for pyruvate - which one can replenish TCA cycle or be used in gluconeogenesis






13. What is the result of vit B5 def






14. How doe NADH electrons from glycolysis and the TCA cycle enter the mitochondiria






15. How does abetalipoproteinemia present and What is the defect






16. What inhibits the carnitine shuttle






17. What is codominance and give an example






18. Gene imprinting implies that How many alleles are active at a single locus






19. cell signaling defect of fibroblast growth factor (FGF) receptor 3 - results in dwarfism - short limbs - head/trunk nl size - associated with advanced paternal age






20. What does the golgi add to serine and threonine residues






21. What are the findings in Lesch - Nyhan






22. What substance inside the cell reduces glutatione






23. What is the activated carrier for electrons






24. What is the RDE of the HMP shunt






25. Where is vit B12 found






26. What are the two transgenic strategies in mice






27. How do cardia glycosides work






28. How do odd chain fatty acids participate in gluconeogenesis






29. Which enzyme involved in RNA synthesis does not require a template






30. What is I cell disease






31. What kind of RNA is transported out of the nucleus






32. What is the name is fxn of vit B3






33. What lab procedure is used to amplify desired fragment of DNA and What are the 3 steps






34. What does a phosphatase do






35. What is used to diagnose muscular dystrophies






36. What are the physical findings of fragile x syndrome






37. How do microtubules grow and collapse






38. What is the initial transcript called and What is the capped and tailed transcript called






39. deletion of VHL gene on chromosome 3 leading to hemangioblastomas of retina/cerebellum/medulla bilateral RCC - dz and overexpression product






40. What is the amino acid precuror for creatine - urea and nitric oxide






41. recurrent pulmonary infxns in CF are due to what organisms






42. progressive neurodegeneration - developmental delay - cherry red spot on macula - lysosomes with onion skin - NO hepatosplenomegaly






43. Describe robertsonian translocation






44. What is NAD+ generally used for






45. What does universal genetic code refer to and What are some exception






46. An inability to convert orotic acid to UMP would be caused by a deficiency either of which two enzymes

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47. What does apoA 1 do






48. Where is glucose 6 phosphatase found and What does it do






49. What lab technique is use to profile gene expression levels of thousands of genes simultaneously to study certain diseases and treatments






50. What enzyme catalyzes the rxn from pyrvuate to Acetyl - CoA and what inhibits it