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Biochemistry

Instructions:
  • Answer 50 questions in 15 minutes.
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  • Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What causes B12 def






2. Mild Hurlurs + aggressive behavior no corneal clouding






3. What is pleiotropy and given an example






4. What are ketone bodies made from - where are they metabolized and how are they excreted






5. nucleotide repeat for fragile x






6. What are the glucogenic essential amino acids






7. What trinucleotide repeat in Huntingtons and what chromosome is it found on...






8. What is the Name and fxn of vit B5






9. What shuttle is used in fatty acid degredation and What does it move and From where to where






10. How do tetracyclines work






11. What is uniparental disomy






12. What are the mRNA stop codons






13. An inability to convert orotic acid to UMP would be caused by a deficiency either of which two enzymes

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14. In which structures do you find microtubules






15. What is a missense mutation






16. What fxn does glucokinase serve in the liver






17. Describe the location and fxn of the Na/K ATPase






18. In what cell is collagen synthesis initiated






19. In addition to fructose and galactose - what sugards should be excluded from the diets of patients with disorders of fructose or galactose metabolism






20. Broadly - What can cause fat - soluble vitamin deficiencies






21. Where are FADH2 electrons transferred to...






22. What inhibits the carnitine shuttle






23. How does ouabain work






24. Type IV BM






25. In prokaryotes - What does makes the different types of RNA






26. What is mosaicism and give an example






27. What is loss of heterozygosity and give an example






28. What are the two possible causes of albinism






29. What are pyrimidines made from






30. What is the results of vit B1 def






31. What does the mutation in the gene cause in protein synthesis






32. Outside the fibroblast What part of procollagen is cleaved and What is it transformed into






33. What does DNA poly I do?






34. Which direction does dynein go






35. FAP is due to deletion On what gene On what chromosome






36. cytoskeletal elements associated with vimenentin - desmin - cytokeratin - glial fibrillary acid protiens (GFAP) - neurofilaments






37. What inhibits pyruvate kinase






38. Inhibition of thymidilate synthase and and DHFR lead to decrease In what substance






39. What substance inside the cell serves to oxidize glutatione






40. What is the activated carrier for Acyl






41. Which tumor suppresors inhibit G1 to S progression - where mutations result in unrestrained growth






42. What does apoE do






43. What does NADPH oxidase deficiency result in and why






44. What part of the pre mRNA contains the actual genetic information coding for protein






45. NADPH are used In what 4 things






46. energy malnutrition resulting in tissues and muscle wasting - loss of subQ fat - variable edema






47. How many rings do pyrimidines have






48. How do fluoroquinolones work






49. What two pathways is carbomoyl phosphate involved in - and what enzyme deficiency leads to a build of carbamoyl phosphate leading to what element in pyrimidine synthesis






50. What causes Edwards syndrome and What is it







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