Test your basic knowledge |

Biochemistry

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What does the primary transcript combine with to form the spliceosome






2. Who typically has lactase def






3. How does ethanol induce hypoglycemia






4. What is the function of folic acid






5. bilateral acoustic schwannomas - juvenile cataracts






6. deletion of VHL gene on chromosome 3 leading to hemangioblastomas of retina/cerebellum/medulla bilateral RCC - dz and overexpression product






7. What enzyme catalyzes the rxn from pyrvuate to Acetyl - CoA and what inhibits it






8. What inhibits the carnitine shuttle






9. What are the two transgenic strategies in mice






10. What is the order of severity for the different types of mutations






11. What does vit E def cause






12. What metabolic rxns occur in both the cytoplasm and mitochondria






13. What are the 3 AR forms of homocystinuria






14. What is the fxn of vit D






15. What is NADPH used for






16. In prokaryotes - What does makes the different types of RNA






17. What happens on the oxidative arm of the HMP shunt and What is the key enzyme






18. recurrent pulmonary infxns in CF are due to what organisms






19. What are cyclins






20. What is the activated carrier for methyl groups






21. What happens at the smooth ER






22. What is the breakdown product of epi






23. fibrillin defect leading to connective tissue disorder affecting skeleton - heart - and eyes






24. Why enzyme breaks down elastin and what enzyme inhibits it






25. What does a northern blot use as its sample






26. What ribosomes do eukaryotes have






27. What does lactase deficiency cause






28. Which type of chromatin is condensed - transcriptionally inactive - sterically inaccessible?






29. What is the energy source in the fed state right after a meal






30. This is the site where negative regulators bind






31. Which bond is stronger AT or CG and why? What is the laboratory consequence of this?






32. Fluorescent DNA or RNA probe binds to specific gene of interest - used for specific localization of genes and direct visualization of anomalies - like microdeletions - at molecular level






33. What occurs to oxaloacetate in starvation and DKA






34. What order kinetics does EtOH dehydrogenase have






35. What is the source of energy in the fasting state between meals






36. What is the treatment for orotic aciduria






37. What defects characterize DiGeorge syndrome






38. What metabolic rxns occur in the cytoplasm






39. What can vit B3 be used to treat






40. What does a pyruvate dehydrogenase deficiency lead to and What are the findings






41. What does the golgi add to serine and threonine residues






42. What does DNA ligase do






43. Of the four possible fates for pyruvate - which one carries amino groups to liver from muscle






44. Why is albinism inheritnace varialbe due to...






45. How does ouabain work






46. How do odd chain fatty acids participate in gluconeogenesis






47. What do DNA topoisomerases do






48. Inhibition of thymidilate synthase and and DHFR lead to decrease In what substance






49. What is the RDE of TCA cycle






50. characterize autosomal domint inheritance