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Biochemistry

Instructions:
  • Answer 50 questions in 15 minutes.
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  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. antbiotic controlled promoter to induciblly manipulate genes at specific developmental points






2. How does patients present with ADPKD






3. What is the treatment for orotic aciduria






4. What kind of branches do glycogen branches have






5. What are covalent alterations






6. What is linkage disequilibrium






7. What is kartageners syndrome






8. What does Alports syndrome cause and why






9. What is maternal PKU






10. How is ammonium transported from muscle to the liver for urea cycle






11. Is there any requirement for homology in NHEJ






12. What is the exception to genetic redundancy






13. What fxn does glucokinase serve in the liver






14. What is NADPH's role inside RBCs






15. What converts NE to epi






16. What is the most abundant protein in the body






17. What converts tyrosine to DOPA






18. What defects characterize velocardiofacial syndrome






19. What does Ehlers Danlos cause and why






20. What are purines made from






21. What defects characterize DiGeorge syndrome






22. What is the breakdown product of epi






23. Which amino acids are elastin rich in






24. recurrent pulmonary infxns in CF are due to what organisms






25. trinucleotide repeat fo myotonic dystrophy






26. What two proteins make up microtubules and how are they arranged






27. What are the fat soluble vitamins and What does their absorption depend on...






28. What is the initial transcript called and What is the capped and tailed transcript called






29. What is dominant negative mutation and give an example






30. Type IV BM






31. What catacholamine step is SAM required for






32. What does a northern blot use as its sample






33. What are cyclins






34. What is the fxn of vit K






35. What is the amino acid precuros for niacin and serotonin/melatonin






36. inc glycogen in muscle but can't break it down - painful muscle cramps - myglobinuria with strenuous exercise - dz and enzyme

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37. In eukaryotes - What does RNA poly I make






38. What is the composition of urea and where do each part derive from






39. What is the activated carrier for Acyl






40. deletion of VHL gene on chromosome 3 leading to hemangioblastomas of retina/cerebellum/medulla bilateral RCC - dz and overexpression product






41. How do cardia glycosides work






42. What lab value can distinguish orotic aciduria from ornithine transcarbamoylase def?






43. What does DNA poly I do?






44. What are possilbe presentation for galactokinase def






45. What is the RDE of ketogenesis






46. What does DNA ligase do






47. metaphse chromosomes are stained - ordered and numbered according to morphology - size - arm length ratio - banding pattern






48. Gene imprinting implies that How many alleles are active at a single locus






49. What is the RDE of fatty acid oxidation






50. In base excision repaire - what recognizes and removes damaged bases and what cuts the DNA to remove the empty sugar