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Biochemistry

Instructions:
  • Answer 50 questions in 15 minutes.
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  • Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Which tumor suppresors inhibit G1 to S progression - where mutations result in unrestrained growth






2. What is the defect in cystinuria






3. What occurs to oxaloacetate in starvation and DKA






4. Very Poor Carbohydrate Metabolism stands for 4 of the glycogen storage diseases - What are thy

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5. What 3 syndromes are associated with vit B1 def






6. What is the function of Zinc






7. What enzyme converts glucose 1 p to UDP glucose






8. How does chloramphenicol work






9. How do odd chain fatty acids participate in gluconeogenesis






10. What is the Name and function of vit B1






11. Which step in the de novo purine and pyrimidine synthesis pathway requires aspartate - glycine - glutamine and THF






12. Describe the location and fxn of the Na/K ATPase






13. What neuroanatomical strutures are injured in wernicke - korsakoff






14. In what direction are DNA and RNA synthesized

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15. What sugar is sorbitol converted to and via what enzyme - and What can happen in cells lacking this enzyme






16. What can vit B3 be used to treat






17. In a marathon Where does energy come from






18. What is the result of vit B5 def






19. What shape does the RNA generate during splicing and why?






20. What is the order of severity for the different types of mutations






21. Type I bone






22. protein malnutrition resulting in skin lesions - edema and liver malfxn






23. What are uncoupling agents






24. What is the exception to genetic redundancy






25. What ribosomes do eukaryotes have






26. In eukaryotes - What does RNA poly II make






27. What CETP do






28. CF - is AR deletion In what gene On what chromosome resulting in a deletion inf what?






29. What liberates glucose from glucose 6 P






30. Of the four possible fates for pyruvate - which one can replenish TCA cycle or be used in gluconeogenesis






31. What are the teratogenic effects of vit A and What test must be ordered before starting a woman on isotreitinoin for severe acne






32. What are the purely ketogenic amino acids






33. fibrillin defect leading to connective tissue disorder affecting skeleton - heart - and eyes






34. What is pleiotropy and given an example






35. What does the golgi add to serine and threonine residues






36. What are the 3 AR forms of homocystinuria






37. What is mosaicism and give an example






38. What enzyme catalyzes the rxn from pyrvuate to Acetyl - CoA and what inhibits it






39. What is the RDE of the HMP shunt






40. What enzyme becomes essential in PKU






41. What is maternal PKU






42. 90% of ADPKD cases are due to a mutation In what gene






43. What induces pyruvate kinase






44. What happens in vit K def






45. What is imprinting and give an example

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46. What happens in carnitine def






47. Type II collagen






48. What feedback inhibits hexokinase






49. What does biotin def cause






50. What is the energy source for tRNA actication (charging)







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