Test your basic knowledge |

Biochemistry

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. deletion of VHL gene on chromosome 3 leading to hemangioblastomas of retina/cerebellum/medulla bilateral RCC - dz and overexpression product






2. What is the function and name of vit B6






3. What does DNA poly III do?






4. central and peripheral demyelination with ataxia and dementia






5. What does a mischarge tRNA do






6. What is pseudohypertrophy in the calf a result of - and What are the cardiac manifestations






7. A small proportion of Down syndrome is due to What two genetic events






8. What is the structure of elastin






9. What is the initial transcript called and What is the capped and tailed transcript called






10. What is the pathway in the fed state leading to dec FBPase -2 and inc PFK-2






11. Which step in the de novo purine and pyrimidine synthesis pathway requires aspartate - glycine - glutamine and THF






12. cell signaling defect of fibroblast growth factor (FGF) receptor 3 - results in dwarfism - short limbs - head/trunk nl size - associated with advanced paternal age






13. What sugar is sorbitol converted to and via what enzyme - and What can happen in cells lacking this enzyme






14. How are the many staggered tropocollagen molecules reinforced






15. What is the RDE of fatty acid synthesis






16. What converts dopamine to NE






17. What defects characterize DiGeorge syndrome






18. Which direction does dynein go






19. What is the active form of vit D






20. facial lesions - hypopigmented 'ash leaf spots -' cortical and retinal hamartomas - seizures - mental retardation - renal cysts - renal angiomyolipomas - cardiac rhabdomyomas - inc risk of astrocytomas






21. What makes up a nucleotide






22. What is regeneration of methionine depedent on...






23. Which type of chromatin is condensed - transcriptionally inactive - sterically inaccessible?






24. What part of the pre mRNA contains the actual genetic information coding for protein






25. What does acetyl - CoA become before becoming palmitate






26. What is variable expression and What is an example






27. What is NADPH's role inside RBCs






28. Of the four possible fates for pyruvate - which one carries amino groups to liver from muscle






29. What causes B12 def






30. What are the names and sources of the two types of vit D found in nature






31. Why enzyme breaks down elastin and what enzyme inhibits it






32. What happens in vit D excess






33. What collagen type is most frequently affected in ehlers danlos and What are common complications






34. What does vit E def cause






35. What are the glucogenic essential amino acids






36. Type IV collagen






37. Describe the pathophys of the aorta in a pt with marfans - and the eyes






38. Which step in the de novo purine and pyrimidine synthesis pathway requires just aspartate






39. What are the findings in orotic aciduria






40. What enzyme converts phenylalanine to tyrosin






41. FAP is due to deletion On what gene On what chromosome






42. Do balanced translocations cause abnl phenotype






43. What are the irreversible enzymes of gluconeogenesis






44. What is the most abundant protein in the body






45. What does cytokeratin stain for






46. What is the results of vit B1 def






47. cardiomegaly - systemic findings leading to early death - dz and enzyme






48. What is the function of Zinc






49. What is the composition of urea and where do each part derive from






50. What apolipoproteins are on chylomicrons