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Biochemistry

Instructions:
  • Answer 50 questions in 15 minutes.
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  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What enzyme becomes essential in PKU






2. Which type of chromatin is less condensed - transcriptionally active - sterically accesible






3. what disease can cause pellagra






4. Type III collagen






5. Describe robertsonian translocation






6. cytoskeletal elements associated with vimenentin - desmin - cytokeratin - glial fibrillary acid protiens (GFAP) - neurofilaments






7. How does ouabain work






8. FAP is due to deletion On what gene On what chromosome






9. What is the TX for CF and What does it do






10. What substances inhibit phosphofructokinase -1






11. What collagen type is most frequently affected in ehlers danlos and What are common complications






12. How many rings do pyrimidines have






13. What neuroanatomical strutures are injured in wernicke - korsakoff






14. What is the composition of urea and where do each part derive from






15. What is the treatment for dec affinity of cystathionine synthase for pyroxidal phosphate






16. What happens do glycogen in skeletal muscle during exercise






17. What is the RDE of cholesterol synthesis






18. What is the activated carrier for aldehyddes






19. What happens in hyperammonemia






20. metaphse chromosomes are stained - ordered and numbered according to morphology - size - arm length ratio - banding pattern






21. Type IV collagen






22. What rxn creates ATP






23. What metabolic rxns occur in the cytoplasm






24. What does hepatic TG lipase do






25. Which aspect of the spliceosome do patients with lupus make antibodies against






26. What do DNA topoisomerases do






27. What defects characterize velocardiofacial syndrome






28. What does aminoacyl tRNA synthetase do the AA before and after it binds to tRNA - and what happens if it's the wrong the match






29. What is the smallest mutation a mircoarray can detect






30. What is the function of folic acid






31. What are the mRNA stop codons






32. What catacholamine step is SAM required for






33. What is incomplete penetrence and give an example






34. What substances are uncouling agents






35. What does high cholesterol or long saturated fatty acid content do to the melting temperature and fluidity






36. congenital microdeletion of long arm of chromosoe 7 with findings of elfin facies - mental retardation - hypercalcemia - well developed verbal skills - extreme friendliness with strangers - cardiovascular problems






37. What tissues have both enzymes of sorbitol metabolism






38. developmental delay - gargoylism - airway obstruction - corneal clouding - hepatosplenomegaly






39. What step of uric acid synthesis does xanthine oxidase catalyze






40. What does DNA poly I do?






41. What does a phosphorylase do






42. How do macrolides and clindamycin work






43. What does Citrate Is Krebs starting substrate for making oxaloacetate






44. What lab technique is use to profile gene expression levels of thousands of genes simultaneously to study certain diseases and treatments






45. How does warfarin work






46. Why can't even chain fatty acids produce new glucose






47. bilateral acoustic schwannomas - juvenile cataracts






48. What is the RDE of TCA cycle






49. energy malnutrition resulting in tissues and muscle wasting - loss of subQ fat - variable edema






50. What does a decrease in decrease in NADPH lead to and why







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