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Biochemistry

Instructions:
  • Answer 50 questions in 15 minutes.
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  • Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What does vit E def cause






2. Which step in the de novo purine and pyrimidine synthesis pathway requires just aspartate






3. What is the breakdown product of NE






4. What happens on the nonoxidative arm of the HMP shunt and What is the key enzyme and cofactor






5. Which direction does dynein go






6. What are the reactants for glycolysis






7. This is the site where negative regulators bind






8. Where do you find elastin and What does it do






9. What is the pathway in the fed state leading to dec FBPase -2 and inc PFK-2






10. Which anti gout drugs work on microtubules






11. What enzyme does fructose metabolism bypass to reach glycolysis






12. RNA poly can't proofread - but What can it do






13. What causes Marfan syndrome






14. What happens in carnitine def






15. Wgat substances directly inhibit mitochondrial ATPase - causing an inc in proton gradient - no ATP because pump is stopped






16. Name 5 drugs that interfere with nucleotide synthesis






17. What shuttle is used in fatty acid degredation and What does it move and From where to where






18. What residues are hydroxylated in step 2 of collagen synthesis - and What does this require






19. What creates the musty body odor in PKU






20. bilateral - massive enlargement of of kidneys due to multiple large cysts






21. What are the glucogenic essential amino acids






22. Of the four possible fates for pyruvate - which one can replenish TCA cycle or be used in gluconeogenesis






23. What is the defect in II A familial hypercholesterolemia






24. What does PURe As Gold and CUT The Py stand for






25. Which end of the tRNA is the amino acid bound to...

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26. What is pseudohypertrophy in the calf a result of - and What are the cardiac manifestations






27. How many ATP are produced by anearobic glycolysis per molecule of glucose






28. What is Retin A used topically for






29. What is the RDE of fatty acid oxidation






30. caf






31. What are the fetal screening measures for Down






32. energy malnutrition resulting in tissues and muscle wasting - loss of subQ fat - variable edema






33. What is the function of Zinc






34. What does high cholesterol or long saturated fatty acid content do to the melting temperature and fluidity






35. What does the CFTR channel do in the lungs - GI tract and skin






36. Pts with albinism are at inc risk For what cancer






37. What does hormone sensitive lipase do






38. What is the RDE of ketogenesis






39. cardiomegaly - systemic findings leading to early death - dz and enzyme

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40. 1 g of protein or cabrohydrate = ?kcal






41. What are the findings with homocystinuria and What amino acid is needs to be supplemented






42. What does NADPH oxidase deficiency result in and why






43. What else can phosphoylate phosphorylase kinase






44. Eukaryotic and prokaryotic DNA synthesis is blank and involves both blank and blank strands






45. What rxn creates ATP






46. What step begins the urea cycle and What is the enzyme needed - Where does it happen






47. Synthesis of vit B3 requires what other vitamin






48. How does ethanol induce hypoglycemia






49. What does amino acid catabolsim results in the formation of what?






50. What is the limiting reagent in EtOH metabolism







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