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Biochemistry

Instructions:
  • Answer 50 questions in 15 minutes.
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  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What drugs can cause folate def






2. What substances directly inhibit electron transport chain






3. What kind of RNA is transported out of the nucleus






4. What two cells are particularly rich in RER






5. What are the fat soluble vitamins and What does their absorption depend on...






6. What is NAD+ generally used for






7. Which step in the de novo purine and pyrimidine synthesis pathway requires aspartate - glycine - glutamine and THF






8. What does fomepizole do






9. delivers hepatic TGs to peripheral tissue - secreted by liver






10. The pyruvate dehydorgenase complex serves In what reaction: reactants






11. Which antihelminthe drugs work on microtubules






12. What are the names and sources of the two types of vit D found in nature






13. What apolipoproteins are on IDL






14. What happens on the oxidative arm of the HMP shunt and What is the key enzyme






15. What is variable expression and What is an example






16. What is the target of the 3' hydroxyl attack






17. Where is vit B12 found






18. What shuttle is involved in fatty acid synthesis and What does it move From where to where






19. I g fat = ? Kcal






20. What are possilbe presentation for galactokinase def






21. What 3 amino acids are necessary for purine synthesis






22. elevated LDL due to defective or absent LDL receptor - heterozygotes have cholesterol ~300 - homozygotes ~700






23. Which tumor suppresors inhibit G1 to S progression - where mutations result in unrestrained growth






24. Describe the location and fxn of the Na/K ATPase






25. Who typically has lactase def






26. What is maternal PKU






27. What are the teratogenic effects of vit A and What test must be ordered before starting a woman on isotreitinoin for severe acne






28. What is the mutation in beckers muscular dystrophy - What is the severity and time of onset






29. Which anti gout drugs work on microtubules






30. What substance inside the cell serves to oxidize glutatione






31. What does the golgi assemble proteoglycans from






32. What are covalent alterations






33. peripheral neuropathy - developmental delay - optic atrophy - glopoid cells






34. cytoskeletal elements associated with cilia - flagella - mitotic spindle - neurones and centrioles






35. What is the pathway in the fasting state leading to inc FBPase -2 and dec PFK-2






36. What is the defect in II A familial hypercholesterolemia






37. What does inc phenylalanine lead to...






38. What test is used for B12 def






39. What does hepatic TG lipase do






40. What chromosome is the NF gene on...






41. Name 5 drugs that interfere with nucleotide synthesis






42. What is the RDE of cholesterol synthesis






43. What does Adenosine deaminase deficiency cause a build up of - and What does that lead to?






44. What 3 syndromes are associated with vit B1 def






45. How many rings do pyrimidines have






46. What are the water soluble vitamins - which ones are stored






47. What is the Name and function of vit B2






48. Where do you find elastin and What does it do






49. What are the findings in orotic aciduria






50. Why is G6PD def more common among patients of african decent