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Biochemistry

Instructions:
  • Answer 50 questions in 15 minutes.
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  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What is the rate determining enzyme (RDE) of glycolysis






2. How many ATP are created by aerobic metobolism of glucose in muslce via what shuttle






3. Leysh - Nyhan syndrome is a defect in which enzyme and What are the biochemical results






4. progressive neurodegeneration - developmental delay - cherry red spot on macula - lysosomes with onion skin - NO hepatosplenomegaly






5. fibrillin defect leading to connective tissue disorder affecting skeleton - heart - and eyes






6. What is RNAi used for






7. How is vit D stored






8. What kind of RNA is transported out of the nucleus






9. characterize autosomal domint inheritance






10. What is the RDE of fatty acid oxidation






11. What is the RDE of the HMP shunt






12. How do fluoroquinolones work






13. What metabolic rxns occur in both the cytoplasm and mitochondria






14. How does insulin inhibit glycogenolysis






15. What is disulfiram used for






16. Give an example of a mitochondrial inherited disease






17. What apolipoprotein is on LDL






18. In which direction is protein synthesized






19. What are bite cells and when do you see them






20. What is locus heterogeneity and give an example






21. What does the golgi do to sugars in proteoglycans and of selected tyrosine on proteins






22. What causes patau's syndrome and What is it






23. What are cyclin - CDK complexes






24. What is the main source of folate






25. What does degenerate/rundant genetic code refer to...






26. What does lactase deficiency cause






27. What makes up a nucleoside






28. What creates the musty body odor in PKU






29. What are uncoupling agents






30. What does the vimentin stain for






31. What does Adenosine deaminase deficiency cause a build up of - and What does that lead to?






32. What is the active form of vit D






33. What is the RDE of ketogenesis






34. How many rings do purines have






35. What are the clinical features of I cell diesase






36. What are the irreversible enzymes of gluconeogenesis






37. peripheral neuropathy - developmental delay - optic atrophy - glopoid cells






38. What does a phosphatase do






39. What happens in hyperammonemia






40. Type II cartilage






41. What enzyme does fructose metabolism bypass to reach glycolysis






42. What happens in vit D excess






43. What converts NE to epi






44. Name as many x- linked recessive disorders as you can

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45. What two cells are particularly rich in RER






46. Fluorescent DNA or RNA probe binds to specific gene of interest - used for specific localization of genes and direct visualization of anomalies - like microdeletions - at molecular level






47. characterize mitochondrial inheritance






48. In a marathon Where does energy come from






49. What is the RER called in neurons and What is made there






50. What does helicase do