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Biochemistry

Instructions:
  • Answer 50 questions in 15 minutes.
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  • Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What other complex is similar to the pyruvate dehydrogenase complex in that it has the same co - factors and generates succinyl - CoA






2. What are the symptoms of vit A def






3. What are the fat soluble vitamins and What does their absorption depend on...






4. What are the complications/signs of familial hypercholesterolemia






5. What happens in a B12 def






6. How does cytosine become uracil






7. The golgi apparatus fxns as a distribution center between what organelles in the cell and What does it process






8. antbiotic controlled promoter to induciblly manipulate genes at specific developmental points






9. fibrillin defect leading to connective tissue disorder affecting skeleton - heart - and eyes






10. Give an example of a mitochondrial inherited disease






11. What defects characterize DiGeorge syndrome






12. What leads to the deletion of the dystrophin gene in duchenne's muscular dystrophy






13. What are the two possible causes of albinism






14. What does Ehlers Danlos cause and why






15. Which are the acidic amino acids






16. What is the purpose of the HMP shunt






17. In addition to fructose and galactose - what sugards should be excluded from the diets of patients with disorders of fructose or galactose metabolism






18. What is the main source of folate






19. what findings are associated with marfans






20. Mild Hurlurs + aggressive behavior no corneal clouding






21. What are possilbe presentation for galactokinase def






22. In which state is PFK-2 active






23. In which single strand DNA repair mechanism do specific endonucleases release the oligonucTIDE containing bases and DNA poly and ligase fill and reseal - and what disease occures when this is mutated






24. What does lactase deficiency cause






25. FAP is due to deletion On what gene On what chromosome






26. What is the function and name of vit B6






27. Of the four possible fates for pyruvate - which one is a transition from glycolysis to TCA cycle






28. What is the result of vit B5 def






29. What are the 3 AR forms of homocystinuria






30. In base excision repaire - what recognizes and removes damaged bases and what cuts the DNA to remove the empty sugar






31. What happens in zinc def






32. How do fluoroquinolones work






33. Why does alpha amanitin cause liver failure and Where is it found






34. characterize mitochondrial inheritance






35. What is the fxn of vit D






36. What enzyme adds Cl - to the H202 to makes bleach






37. trinucleotide repeat for huntingtons






38. What is the most abundant type of RNA






39. What is Gowers maneuver






40. In eukaryotes - What does RNA poly III make






41. What sugar is sorbitol converted to and via what enzyme - and What can happen in cells lacking this enzyme






42. What is the complication of cystinuria






43. What is the Name and fxn of vit B5






44. What is the longest time of RNA and shortest






45. What is the RDE of the HMP shunt






46. What does DNA ligase do






47. What is the amino acid precuror for creatine - urea and nitric oxide






48. What is used to diagnose muscular dystrophies






49. What is a missense mutation






50. benign asymptomatic condition with elevated levels of fructose in urine and blood - dz and enzyme