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Biochemistry

Instructions:
  • Answer 50 questions in 15 minutes.
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  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Name as many x- linked recessive disorders as you can

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2. What happens in folate def






3. What regulates whether FBPase -2 or PFK-2 is active






4. Where is vit B12 found






5. Type II collagen






6. What are the results of CF on male fertility






7. What is the Name and function of vit B2






8. What is the amino acid precursor for histamine






9. What is the defect in II A familial hypercholesterolemia






10. In which direction is protein synthesized






11. What is the smallest mutation a mircoarray can detect






12. How does abetalipoproteinemia present and What is the defect






13. What produces NADPH






14. What is the prevalence of an X- linked recessive disease in males and in females






15. What is the fxn of vit K






16. What is the active form of vit D






17. What apolipoproteins are on chylomicrons






18. What is the RDE of the HMP shunt






19. What is the TX for PKU






20. What kind of branches do glycogen branches have






21. What clotting factors require vit K






22. phosphorylation of glucose to yield glucose 6 phosphate serves as the 1st step of what rxns and what enzymes catalyze it






23. What 3 amino acids are necessary for purine synthesis






24. What substance inside the cells replenishes NADPH






25. What liberates glucose from glucose 6 P






26. What is maternal PKU






27. What causes Down syndrome






28. What does the golgi add to serine and threonine residues






29. What lab value can distinguish orotic aciduria from ornithine transcarbamoylase def?






30. What ribosomes do prokaryotes have






31. What is the defect in cystinuria






32. In which state is FBPase -2 active






33. An inability to convert orotic acid to UMP would be caused by a deficiency either of which two enzymes

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34. Which step in the de novo purine and pyrimidine synthesis pathway requires aspartate - glycine - glutamine and THF






35. Is there any requirement for homology in NHEJ






36. What causes Marfan syndrome






37. How does cytosine become uracil






38. What does helicase do






39. Describe the structure of cilia






40. What are purines made from






41. What does a kinase do






42. How do stable (quiescent) cells grow and regenerate and What are examples






43. Which bond is stronger AT or CG and why? What is the laboratory consequence of this?






44. What is the complication of cystinuria






45. What is the RDE of de novo pyrimidine synthesis






46. peripheral neuropathy of hands/feet - angiokeratomas - CV/renal disease - dz - def enzyme - acc substrate - inherit






47. What is the function and name of vit B6






48. Where does gluconeogenesis primarily happen and What are other sites where the enzymes are located






49. What is loss of heterozygosity and give an example






50. What does NADPH oxidase deficiency result in and why