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Biochemistry

Instructions:
  • Answer 50 questions in 15 minutes.
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  • Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What chromosome is the NF gene on...






2. What does a dehydrogenase do






3. FAP is due to deletion On what gene On what chromosome






4. What does CATCH 22 stand for and What causes is...






5. What enzyme does fructose metabolism bypass to reach glycolysis






6. What is the initial transcript called and What is the capped and tailed transcript called






7. What are the teratogenic effects of vit A and What test must be ordered before starting a woman on isotreitinoin for severe acne






8. What is the activated carrier for phosphoryl






9. What is the activated carrier for methyl groups






10. How is ammonium transported from muscle to the liver for urea cycle






11. How is orotic aciduria inherited






12. What collagen type is most frequently affected in ehlers danlos and What are common complications






13. 1 g of protein or cabrohydrate = ?kcal






14. What is the defect in cystinuria






15. What two rxns in in glycolysis require ATP






16. What is a nonsense mutation






17. What makes up a nucleotide

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18. Describe the replication fork






19. hepatosplenomegaly - aseptic necrosis of femur - bone crisis - MACS that look like crumpled tissue paper

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20. Infection with what organism can cause B12 def






21. What enzyme adds Cl - to the H202 to makes bleach






22. peripheral neuropathy of hands/feet - angiokeratomas - CV/renal disease - dz - def enzyme - acc substrate - inherit






23. Describe the structure of cilia






24. What does vit C def cause






25. Which amino acids are elastin rich in






26. What bone disorder has x linked dominant inheritance






27. What is the amino acid precursor for catecholamines






28. How does OTC def present






29. inc glycogen in muscle but can't break it down - painful muscle cramps - myglobinuria with strenuous exercise - dz and enzyme

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30. What do the single stranded binding proteins do






31. Of the four possible fates for pyruvate - which ends anaerobic glycolysis as in RBCs - leukocytes - kidney medulla - lens - testes and cornea






32. How does patients present with ADPKD






33. Which bond is stronger AT or CG and why? What is the laboratory consequence of this?






34. Describe robertsonian translocation






35. What causes Edwards syndrome and What is it






36. What defects characterize velocardiofacial syndrome






37. progressive neurodegeneration - hepatosplenomegaly - cherry red spot on macula - foam cells






38. What produces NADPH






39. Of the four possible fates for pyruvate - which one is a transition from glycolysis to TCA cycle






40. What substance inside the cell reduces glutatione






41. How do aminoglycosides work






42. What does apoE do






43. What is the most common urea cycle disorder and What is the mode of inheritance?






44. Describe the location and fxn of the Na/K ATPase






45. Type IV collagen






46. What does apoB48 do






47. What does high cholesterol or long saturated fatty acid content do to the melting temperature and fluidity






48. What makes up a nucleoside






49. What happens in termination of proteins synthesis






50. How do glucagon/epi lead to glycogenolysis







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