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Biochemistry

Instructions:
  • Answer 50 questions in 15 minutes.
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  • Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What does the golgi add to serine and threonine residues






2. What does universal genetic code refer to and What are some exception






3. What apolipoprotiens are on VLDL






4. What is the RDE of gluconeogenesis






5. What are the 2 distinct phases of the HMP shunt and How many ATP are used and produced






6. What is the source of energy in the fasting state between meals






7. What causes Down syndrome






8. What are the results of CF on male fertility






9. facial lesions - hypopigmented 'ash leaf spots -' cortical and retinal hamartomas - seizures - mental retardation - renal cysts - renal angiomyolipomas - cardiac rhabdomyomas - inc risk of astrocytomas






10. What enzyme becomes essential in PKU






11. Type I collagen






12. What collagen type is most frequently affected in ehlers danlos and What are common complications






13. What is loss of heterozygosity and give an example






14. recurrent pulmonary infxns in CF are due to what organisms






15. What do DNA topoisomerases do






16. What are purines made from






17. What happens in vit B2 def






18. What are cyclins






19. Broadly - What can cause fat - soluble vitamin deficiencies






20. What is the activated carrier for Co2






21. How do macrolides and clindamycin work






22. What sugar is sorbitol converted to and via what enzyme - and What can happen in cells lacking this enzyme






23. What is the RDE of glycogenolysis






24. How does OTC def present






25. Where is glucokinase found - What are the Km and Vmax - and what induces it






26. What does beta oxidation do and Where does it occur






27. What is the function of biotin






28. What substance accumulates in galactokinase def and What is the clinical picture






29. Which anti gout drugs work on microtubules






30. What are the 4 assumption of the Hardy Weinberg law






31. The pyruvate dehydorgenase complex serves In what reaction: reactants






32. energy malnutrition resulting in tissues and muscle wasting - loss of subQ fat - variable edema






33. What are Heinz bodies






34. What is a frame shift






35. antbiotic controlled promoter to induciblly manipulate genes at specific developmental points






36. pyruvate carboxylase catalyzes what rxn






37. In which single strand DNA repair mechanism do specific endonucleases release the oligonucTIDE containing bases and DNA poly and ligase fill and reseal - and what disease occures when this is mutated






38. What polar group does guanine have - and what non polar group does thymine have






39. What shape does the RNA generate during splicing and why?






40. What is NADPH's role inside RBCs






41. What are the irreversible enzymes of gluconeogenesis






42. What is the defect in I- hyperchylomicronemia






43. What does a phosphatase do






44. What does the golgi apparatus do on asparagine






45. How does patients present with ADPKD






46. What is the activated carrier for 1 carbon units






47. characterize autosomal recessive inheritance






48. What is the active form of vit D






49. What are the two possible causes of albinism






50. How many rings do pyrimidines have







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