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First Aid Basics

Subjects : health-sciences, first-aid

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Heart disease
Alkylating agents target
Leading cause of death in the US
Paget's bone disease
blood vessels benign tumor

2. Adenoma - papilloma
Second - leading cause of death in the US
ret gene
Napthalene (aniline) dyes target
benign epithelial tumor

3. Tumor marker: mets to bone - obstructive biliary disease - Paget's
Colon and rectal cancer incidence
Alk - phos
Leukocyte extravasation: migration
Free radical eliminators

4. 32%/13% male
malignant >1 cell type tumor
prostate cancer incidence/mortality
Bombesin
arsenic target

5. Tumor marker: tartrate - resistant acid phosphatase. Hairy cell leukemia (B- cell neoplasm)
Rb gene
fat malignant tumor
TRAP
Red (hemorrhagic) infarcts

6. Malignant melanoma
Alkylating agents target
dysplastic nevus
Alk - phos
extrinsic apoptosis

7. Leiomyoma
prostate cancer incidence/mortality
CA-19-9
p16 gene
smooth muscle benign tumor

8. Vascular: ICAM-1 Leukocyte: LFA-1 (integrin)
Colon and rectal cancer incidence
Leukocyte extravasation: tight binding
Primary tumors that met to brain
lung cancer incidence/mortality

9. Breast - ovarian and gastric carcinomas tyrosine kinase (oncogene)
erb - B2 gene
beta - hCG
Free radical eliminators
fat benign tumor

10. TB - fungal infections - syphilis - leprosy - cat scratch fever - sarcoid - Crohn's - Berylliosis.
fat malignant tumor
WT1 gene
granulomatous disease
Leukocyte extravasation: tight binding

11. Bladder (transitional cell carcinoma)
Napthalene (aniline) dyes target
cirrosis (alcohol - hepB or C)
Pale infarcts
malignant epithelial tumor

12. Lung - breast - skin (melanoma) - kidney (renal cell carcinoma) - GI.50% brain tumors are from mets
arsenic target
Primary tumors that met to brain
Free radical cell damage
Second - leading cause of death in the US

13. Solid tissues with single blood supply. Heart - kidney and spleen.
Prostatic acid phosphatase
fat benign tumor
Pale infarcts
primary amyloidosis

14. Colorectal cancer (assoc with FAP) 5q tumor suppressor
CCl4 target
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants
Autoimmune (Hashimoto's - myasthenia gravis)
APC gene

15. Hyperuricemia (excess NA turnover)
CEA
paraneoplastic effects of leukemias and lymphomas
skeletal muscle benign tumor
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)

16. Lung - liver - intestine or following reperfusion.
paraneoplastic effects of thymoma - small cell lung carcinoma
fat malignant tumor
nitrosamines (smoked foods) target
Red (hemorrhagic) infarcts

17. Liver (hepatocellular carcinoma)
cirrosis (alcohol - hepB or C)
Alk - phos
p16 gene
aflatoxin target

18. Tumor marker: melanoma - neural tumors - astrocytomas
cigarette smoke target
S-100
prostate cancer incidence/mortality
Chronic inflammatory mediators

19. ACTH or ACTH- like peptide
Chronic inflammatory mediators
c - kit gene
Alkylating agents target
paraneoplastic effects of small cell lung carcinoma

20. Esophagus - stomach
malignant epithelial tumor
nitrosamines (smoked foods) target
Napthalene (aniline) dyes target
intrinsic apoptosis

21. Ligand - receptor interactions. Release of perforin and granzyme B.
granulomatous disease
DCC gene
bone benign tumor
extrinsic apoptosis

22. Neurofibromatosis type 2 22q tumor suppressor (key type 2=22)
Where you see Psammoma bodies
bone malignant tumor
NF2 gene
causes of decreased ESR

23. CML tyrosine kinase (oncogene)
Leukocyte extravasation: tight binding
radiation exposure
causes of decreased ESR
abl gene

24. Neutrophils (eos in the gut) - plus other granular leukocytes and antibodies.
Resolution of inflammation
Napthalene (aniline) dyes target
blood vessels malignant tumor
Acute inflammatory mediators

25. Caused by peroxidation of membrane lipids. Causes acute gastric bleeding and chronic metabolic acidosis and scarring.
aflatoxin target
arsenic target
iron poisoning
beta - hCG

26. Rhabdomyoma
Barrett's esophagus (chronic GI reflux)
dysplastic nevus
ulcerative colitis
skeletal muscle benign tumor

27. Liposarcoma
Neoplasm associated with actinic keratosis
fat malignant tumor
PSA
Leukocyte extravasation: migration

28. Wilms' tumor 11p tumor suppressor
malignant epithelial tumor
Second - leading cause of death in the US
Reversible - plasias
WT1 gene

29. MEN type II and III tyrosine kinase (oncogene)
ret gene
Free radical eliminators
granulomatous disease
blood vessels benign tumor

30. Mature teratoma in men or malignant teratoma in M/F
p53 gene
malignant >1 cell type tumor
causes of decreased ESR
beta - hCG

31. Osteosarcoma
bone malignant tumor
skeletal muscle benign tumor
CCl4 target
Napthalene (aniline) dyes target

32. Most human cancers - specifically Li - Fraumeni syndrome 17p tumor suppressor (blocks G1 to S phase progression)
Primary tumors that met to liver
asbestos target
p53 gene
benign >1 cell type tumor

33. Tumor marker: pancreatic adenocarcinoma
skeletal muscle benign tumor
Leukocyte extravasation: migration
CA-19-9
fat malignant tumor

34. All - AML
Neoplasm associated with Down Syndrome
breast cancer incidence/mortality
ras gene
blood vessels malignant tumor

35. Tumor marker: Hydatifiform moles - choriocarcinomas - gestational trophoblastic tumors.
causes of decreased ESR
Leading cause of death in the US
radiation exposure
beta - hCG

36. Esophageal adenocarcinoma

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37. Enzymes: catalase - superoxide dismutase - glutathione peroxidase.Vitamins: ACE Spontaneous decay
iron poisoning
cigarette smoke target
Resolution of inflammation
Free radical eliminators

38. AL
Where you see Psammoma bodies
primary amyloidosis
smooth muscle malignant tumor
vinyl chloride target

39. Malignant lymphoma
blood cell malignant tumors
DPC gene
immunodeficiency states
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants

40. Colon carcinoma GTPase (oncogene)
ras gene
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)
Leukocyte extravasation: migration
Primary tumors that met to liver

41. Skin (SqCC) - liver (angiosarcoma)
arsenic target
malignant mesenchyme tumor (general)
DPC gene
CEA

42. Liver (centrilobular necrosis - fatty change)
paraneoplastic effects of small cell lung carcinoma
CCl4 target
immunodeficiency states
Leukocyte extravasation: migration

43. PECAM-1
Leukocyte extravasation: diapedesis
Where you see Psammoma bodies
fat malignant tumor
blood vessels malignant tumor

44. ADH
smooth muscle benign tumor
erb - B2 gene
immunodeficiency states
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms

45. Lipoma
fat benign tumor
radiation exposure
vinyl chloride target
DPC gene

46. Tumor marker: thyroid medullary carcinoma
Prostatic acid phosphatase
CEA
calcitonin
alpha - fetoprotein

47. Cancer
Leukocyte extravasation: migration
Second - leading cause of death in the US
Bombesin
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)

48. PTH- related peptide - TGF- beta - TNF - IL-1
L- myc gene
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.
Pale infarcts
c - kit gene

49. Colon>stomach>pancreas>breast>lung (liver and lung are the most common places for mets)
Primary tumors that met to liver
Resolution of inflammation
benign >1 cell type tumor
Where you see Psammoma bodies

50. Visceral malignancy (stomach - lung - breast - uterus)
c - kit gene
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)
acanthosis nigricans (hyperpig and epidermal thickening)
malignant epithelial tumor

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First Aid Basics

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