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First Aid Basics

Subjects : health-sciences, first-aid

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Tumor marker: carcinoembryonic Ag Very nonspecific
aflatoxin target
c - kit gene
APC gene
CEA

2. Colonic adenocarcinoma
ulcerative colitis
erb - B2 gene
calcitonin
Resolution of inflammation

3. Tumor marker: tartrate - resistant acid phosphatase. Hairy cell leukemia (B- cell neoplasm)
Alk - phos
aflatoxin target
TRAP
Second - leading cause of death in the US

4. CML tyrosine kinase (oncogene)
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms
abl gene
cirrosis (alcohol - hepB or C)
Rb gene

5. Breast cancer 13q tumor suppressor (DNA repair protein)
Alk - phos
BRAC2 gene
bone malignant tumor
skeletal muscle malignant tumor

6. Neurofibromatosis type 2 22q tumor suppressor (key type 2=22)
Rb gene
BRAC2 gene
NF2 gene
Free radical eliminators

7. Tumor marker: prostate carcinoma marker.
NF1 gene
bcl -2 gene
nitrosamines (smoked foods) target
Prostatic acid phosphatase

8. Hemangioma
blood vessels benign tumor
Leukocyte extravasation: diapedesis
PSA
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms

9. Melanoma 9p tumor suppressor
p16 gene
benign >1 cell type tumor
skeletal muscle benign tumor
PSA

10. Wilms' tumor 11p tumor suppressor
Leukocyte extravasation: rolling
Second - leading cause of death in the US
extrinsic apoptosis
WT1 gene

11. Rhabdomyoma
skeletal muscle benign tumor
Free radical eliminators
DCC gene
immunodeficiency states

12. PECAM-1
immunodeficiency states
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms
Leukocyte extravasation: diapedesis
BRAC2 gene

13. Tumor marker: Screen for prostate carcinoma. Can also be elevated in BPH and prostatitis.
CA-19-9
PSA
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)
vinyl chloride target

14. All - AML
WT1 gene
CEA
smooth muscle malignant tumor
Neoplasm associated with Down Syndrome

15. Retinoblastoma - osteosarcoma 13q tumor suppressor (blocks G1 to S phase progression)
WT1 gene
Rb gene
Alkylating agents target
Colon and rectal cancer incidence

16. Enzymatic degradation and protein denaturation due to exogenous injury. Inflammatory process where intracellular components extravasate.
Necrosis
causes of decreased ESR
malignant >1 cell type tumor
Barrett's esophagus (chronic GI reflux)

17. Secondary osteosarcoma and fibrosarcoma
Paget's bone disease
malignant >1 cell type tumor
PSA
extrinsic apoptosis

18. Squamous cell carcinoma of skin
Neoplasm associated with actinic keratosis
blood vessels benign tumor
Red (hemorrhagic) infarcts
Napthalene (aniline) dyes target

19. Astrocytoma - angiomyolipoma - cardiac rhabdomyoma
fat benign tumor
Leukocyte extravasation: migration
Prostatic acid phosphatase
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)

20. Erythropoietin
CEA
WT1 gene
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
Leukocyte extravasation: tight binding

21. Colon cancer (Deleted in Colon Cancer) 18q tumor suppressor
p53 gene
DPC gene
Free radical eliminators
DCC gene

22. Rhabdomyosarcoma
malignant >1 cell type tumor
Where you see Psammoma bodies
skeletal muscle malignant tumor
NF2 gene

23. Squamous cell carcinoma of the esophagus
NF1 gene
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)
p53 gene
paraneoplastic effects of thymoma - small cell lung carcinoma

24. ACTH or ACTH- like peptide
Necrosis
paraneoplastic effects of small cell lung carcinoma
skeletal muscle malignant tumor
radiation exposure

25. Bladder (transitional cell carcinoma)
Second - leading cause of death in the US
benign epithelial tumor
Napthalene (aniline) dyes target
DCC gene

26. Infections - inflammation - cancer - pregnancy - SLE
cirrosis (alcohol - hepB or C)
Barrett's esophagus (chronic GI reflux)
causes of increased ESR
paraneoplastic effects of leukemias and lymphomas

27. Esophagus - stomach
NF2 gene
vinyl chloride target
nitrosamines (smoked foods) target
N- myc gene

28. Gastric adenocacinoma
breast cancer incidence/mortality
lung cancer incidence/mortality
bone malignant tumor
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants

29. Liver (centrilobular necrosis - fatty change)
CCl4 target
Necrosis
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
Primary tumors that met to bone

30. Vascular: ICAM-1 Leukocyte: LFA-1 (integrin)
Leukocyte extravasation: tight binding
smooth muscle malignant tumor
Acute inflammatory mediators
breast cancer incidence/mortality

31. Pancreatic cancer (Deleted in Pancreatic Cancer) 18q tumor suppressor
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms
acanthosis nigricans (hyperpig and epidermal thickening)
Alk - phos
DPC gene

32. Colorectal cancer (assoc with FAP) 5q tumor suppressor
blood cell malignant tumors
erb - B2 gene
PSA
APC gene

33. GIST cytokine receptor (oncogene)
Leukocyte extravasation: rolling
c - kit gene
iron poisoning
smooth muscle malignant tumor

34. Tumor marker: pancreatic adenocarcinoma
S-100
L- myc gene
DCC gene
CA-19-9

35. Tumor marker: neuroblastoma - lung and gastric cancer
BRAC2 gene
Bombesin
blood vessels benign tumor
NF1 gene

36. Adenoma - papilloma
asbestos target
benign epithelial tumor
intrinsic apoptosis
L- myc gene

37. Caused by peroxidation of membrane lipids. Causes acute gastric bleeding and chronic metabolic acidosis and scarring.
beta - hCG
smooth muscle malignant tumor
iron poisoning
extrinsic apoptosis

38. Tumor marker: thyroid medullary carcinoma
Napthalene (aniline) dyes target
ulcerative colitis
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)
calcitonin

39. 32%/13% male
arsenic target
prostate cancer incidence/mortality
Primary tumors that met to brain
bone malignant tumor

40. Hyperuricemia (excess NA turnover)
paraneoplastic effects of leukemias and lymphomas
nitrosamines (smoked foods) target
Leukocyte extravasation: migration
Autoimmune (Hashimoto's - myasthenia gravis)

41. Lung (mesothelioma and bronchogenic carcinoma)
bone benign tumor
cigarette smoke target
asbestos target
Primary tumors that met to brain

42. 32%/18% female
DCC gene
ret gene
breast cancer incidence/mortality
asbestos target

43. Melanoma - basal cell carcinoma - and especially squamous cell carcinomas of the skin.
Primary tumors that met to liver
Neoplasm associated with xeroderma pigmentosum (albinism)
radiation exposure
Free radical cell damage

44. Esophageal adenocarcinoma
Free radical cell damage
Pale infarcts
Barrett's esophagus (chronic GI reflux)
Neoplasm associated with Down Syndrome

45. Lipoma
paraneoplastic effects of small cell lung carcinoma
nitrosamines (smoked foods) target
fat benign tumor
Neoplasm associated with actinic keratosis

46. Tumor marker: melanoma - neural tumors - astrocytomas
paraneoplastic effects of thymoma - small cell lung carcinoma
Primary tumors that met to brain
PSA
S-100

47. Ligand - receptor interactions. Release of perforin and granzyme B.
extrinsic apoptosis
fat malignant tumor
Free radical eliminators
smooth muscle malignant tumor

48. Antibodies to presynaptic Ca2+ channels at NM junction
lung cancer incidence/mortality
malignant >1 cell type tumor
paraneoplastic effects of thymoma - small cell lung carcinoma
Leukocyte extravasation: tight binding

49. Breast and ovarian cancer 17q tumor suppressor (DNA repair protein)
c - kit gene
BRCA1 gene
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)
paraneoplastic effects of small cell lung carcinoma

50. MEN type II and III tyrosine kinase (oncogene)
NF2 gene
CA-19-9
ret gene
Autoimmune (Hashimoto's - myasthenia gravis)

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