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First Aid Basics

Subjects : health-sciences, first-aid

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Antibodies to presynaptic Ca2+ channels at NM junction
APC gene
cigarette smoke target
paraneoplastic effects of thymoma - small cell lung carcinoma
bone malignant tumor

2. Follicular and undifferentiated lymphomas anti - apoptotic molecule (oncogene)
Barrett's esophagus (chronic GI reflux)
Resolution of inflammation
paraneoplastic effects of small cell lung carcinoma
bcl -2 gene

3. Ligand - receptor interactions. Release of perforin and granzyme B.
extrinsic apoptosis
S-100
ras gene
blood cell malignant tumors

4. Breast - ovarian and gastric carcinomas tyrosine kinase (oncogene)
Napthalene (aniline) dyes target
erb - B2 gene
N- myc gene
skeletal muscle benign tumor

5. Tumor marker: mets to bone - obstructive biliary disease - Paget's
Free radical eliminators
fat benign tumor
WT1 gene
Alk - phos

6. Skin (SqCC) - liver (angiosarcoma)
WT1 gene
dysplastic nevus
N- myc gene
arsenic target

7. Neurofibromatosis type 1 17q tumor suppressor
arsenic target
cirrosis (alcohol - hepB or C)
NF1 gene
causes of increased ESR

8. Larynx (SqCC) - lung (SqCC and SCC) - kidney (renal cell carcinoma) - bladder (transitional cell carcinoma)
cigarette smoke target
primary amyloidosis
paraneoplastic effects of small cell lung carcinoma
granulomatous disease

9. Erythropoietin
Resolution of inflammation
blood vessels benign tumor
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
PSA

10. Lipoma
calcitonin
malignant >1 cell type tumor
causes of increased ESR
fat benign tumor

11. Sarcoma
causes of increased ESR
smooth muscle benign tumor
malignant mesenchyme tumor (general)
ras gene

12. Leiomyoma
APC gene
smooth muscle benign tumor
Neoplasm associated with actinic keratosis
Leading cause of death in the US

13. Tumor marker: thyroid medullary carcinoma
Pale infarcts
cigarette smoke target
calcitonin
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)

14. Rhabdomyoma
skeletal muscle malignant tumor
skeletal muscle benign tumor
erb - B2 gene
CEA

15. Pancreatic cancer (Deleted in Pancreatic Cancer) 18q tumor suppressor
DPC gene
causes of increased ESR
malignant epithelial tumor
blood cell malignant tumors

16. Colon carcinoma GTPase (oncogene)
S-100
p16 gene
Leading cause of death in the US
ras gene

17. PTH- related peptide - TGF- beta - TNF - IL-1
bone malignant tumor
Leukocyte extravasation: diapedesis
Neoplasm associated with Down Syndrome
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.

18. Malignant melanoma
dysplastic nevus
skeletal muscle malignant tumor
radiation exposure
benign >1 cell type tumor

19. TB - fungal infections - syphilis - leprosy - cat scratch fever - sarcoid - Crohn's - Berylliosis.
granulomatous disease
fat benign tumor
asbestos target
NF1 gene

20. Female 13% Male 12%
skeletal muscle benign tumor
cirrosis (alcohol - hepB or C)
Colon and rectal cancer incidence
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.

21. Tumor marker: tartrate - resistant acid phosphatase. Hairy cell leukemia (B- cell neoplasm)
TRAP
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)
CA-125
malignant epithelial tumor

22. Breast and ovarian cancer 17q tumor suppressor (DNA repair protein)
BRCA1 gene
Neoplasm associated with xeroderma pigmentosum (albinism)
c - kit gene
Reversible - plasias

23. Infections - inflammation - cancer - pregnancy - SLE
WT1 gene
Free radical eliminators
causes of increased ESR
vinyl chloride target

24. Hemangioma
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)
breast cancer incidence/mortality
N- myc gene
blood vessels benign tumor

25. Heart disease
Neoplasm associated with xeroderma pigmentosum (albinism)
alpha - fetoprotein
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.
Leading cause of death in the US

26. Osteoma
bone benign tumor
immunodeficiency states
Irreversible - plasias
skeletal muscle benign tumor

27. Vascular: E and P- selectin Leukocyte: Sialyl Lewis
Leukocyte extravasation: rolling
CA-19-9
intrinsic apoptosis
p16 gene

28. Enzymes: catalase - superoxide dismutase - glutathione peroxidase.Vitamins: ACE Spontaneous decay
Free radical eliminators
BRAC2 gene
malignant >1 cell type tumor
Primary tumors that met to brain

29. ADH
lung cancer incidence/mortality
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms
TRAP
Prostatic acid phosphatase

30. Breast cancer 13q tumor suppressor (DNA repair protein)
c - myc gene
causes of increased ESR
Red (hemorrhagic) infarcts
BRAC2 gene

31. AA
Alk - phos
AIDS
secondary amyloidosis (reactive systemic)
radiation exposure

32. Adenocarcinoma - papillary carcinoma
benign epithelial tumor
malignant epithelial tumor
Barrett's esophagus (chronic GI reflux)
Leukocyte extravasation: rolling

33. Membrane lipid peroxidation - protein modification and DNA breakage.
Chronic inflammatory mediators
Free radical cell damage
ret gene
arsenic target

34. Cancer
blood cell malignant tumors
NF2 gene
Second - leading cause of death in the US
breast cancer incidence/mortality

35. Liver (angiosarcoma)
WT1 gene
secondary amyloidosis (reactive systemic)
vinyl chloride target
Resolution of inflammation

36. Female 13%/23% and rising Male 16%/33% (mortality has plateaued)
Leukocyte extravasation: migration
lung cancer incidence/mortality
BRCA1 gene
Neoplasm associated with actinic keratosis

37. Blood (leukemia)
Alkylating agents target
Neoplasm associated with xeroderma pigmentosum (albinism)
smooth muscle benign tumor
Rb gene

38. Melanoma - basal cell carcinoma - and especially squamous cell carcinomas of the skin.
Neoplasm associated with xeroderma pigmentosum (albinism)
Chronic inflammatory mediators
Prostatic acid phosphatase
blood vessels benign tumor

39. Macrophages and lymphocytes. Persistant destruction and repair.
calcitonin
Red (hemorrhagic) infarcts
Chronic inflammatory mediators
p16 gene

40. Gastric adenocacinoma
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants
blood vessels benign tumor
aflatoxin target
DCC gene

41. GIST cytokine receptor (oncogene)
benign >1 cell type tumor
causes of decreased ESR
aflatoxin target
c - kit gene

42. Tumor marker: carcinoembryonic Ag Very nonspecific
Free radical cell damage
CEA
APC gene
bone benign tumor

43. Tumor marker: prostate carcinoma marker.
Red (hemorrhagic) infarcts
paraneoplastic effects of thymoma - small cell lung carcinoma
cirrosis (alcohol - hepB or C)
Prostatic acid phosphatase

44. Adenoma - papilloma
Napthalene (aniline) dyes target
benign epithelial tumor
smooth muscle benign tumor
nitrosamines (smoked foods) target

45. Tumor marker: ovarian - malignant epithelial tumors.
blood vessels malignant tumor
Leukocyte extravasation: diapedesis
secondary amyloidosis (reactive systemic)
CA-125

46. Visceral malignancy (stomach - lung - breast - uterus)
acanthosis nigricans (hyperpig and epidermal thickening)
aflatoxin target
Necrosis
nitrosamines (smoked foods) target

47. Sarcoma - papillary thyroid cancer
bone malignant tumor
Where you see Psammoma bodies
paraneoplastic effects of leukemias and lymphomas
radiation exposure

48. Sickle cell (altered shape) - polycythemia (too many) - CHF (unknown)
causes of decreased ESR
iron poisoning
N- myc gene
Second - leading cause of death in the US

49. During embryogenesis - hormone induction and atrophy. Increased mitochondrial permeability and cytochrome c release. Increase Bax (pro - apoptotic) - decreased Bcl -2 (anti - apopotic).
CA-19-9
intrinsic apoptosis
smooth muscle benign tumor
bone benign tumor

50. MEN type II and III tyrosine kinase (oncogene)
NF1 gene
Neoplasm associated with actinic keratosis
malignant >1 cell type tumor
ret gene

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First Aid Basics

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