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First Aid Basics

Subjects : health-sciences, first-aid

Instructions:

Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can study here.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Sickle cell (altered shape) - polycythemia (too many) - CHF (unknown)
causes of decreased ESR
PSA
Rb gene
blood cell malignant tumors

2. Neurofibromatosis type 1 17q tumor suppressor
Neoplasm associated with actinic keratosis
Reversible - plasias
primary amyloidosis
NF1 gene

3. Liver (hepatocellular carcinoma)
aflatoxin target
radiation exposure
Red (hemorrhagic) infarcts
Barrett's esophagus (chronic GI reflux)

4. Mature teratoma in men or malignant teratoma in M/F
breast cancer incidence/mortality
malignant >1 cell type tumor
Necrosis
Resolution of inflammation

5. Hepatocellular carcinoma
Pale infarcts
cirrosis (alcohol - hepB or C)
dysplastic nevus
lung cancer incidence/mortality

6. Malignant lymphoma
NF1 gene
breast cancer incidence/mortality
immunodeficiency states
L- myc gene

7. Enzymes: catalase - superoxide dismutase - glutathione peroxidase.Vitamins: ACE Spontaneous decay
Free radical eliminators
blood cell malignant tumors
bcl -2 gene
TRAP

8. Tumor marker: Hydatifiform moles - choriocarcinomas - gestational trophoblastic tumors.
benign epithelial tumor
beta - hCG
secondary amyloidosis (reactive systemic)
Colon and rectal cancer incidence

9. Bacterial products (CLIK):C5a - LTB4 - IL-8 - Kallikrein
CCl4 target
Leading cause of death in the US
Leukocyte extravasation: migration
Bombesin

10. Tumor marker: tartrate - resistant acid phosphatase. Hairy cell leukemia (B- cell neoplasm)
smooth muscle malignant tumor
Neoplasm associated with Down Syndrome
intrinsic apoptosis
TRAP

11. Erythropoietin
ret gene
Leukocyte extravasation: rolling
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
iron poisoning

12. Tumor marker: melanoma - neural tumors - astrocytomas
Pale infarcts
S-100
primary amyloidosis
BRCA1 gene

13. Macrophages and lymphocytes. Persistant destruction and repair.
bcl -2 gene
CA-125
Chronic inflammatory mediators
p16 gene

14. Rhabdomyoma
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants
Barrett's esophagus (chronic GI reflux)
skeletal muscle benign tumor
malignant >1 cell type tumor

15. Female 13% Male 12%
Leukocyte extravasation: rolling
CA-19-9
Colon and rectal cancer incidence
paraneoplastic effects of thymoma - small cell lung carcinoma

16. Most human cancers - specifically Li - Fraumeni syndrome 17p tumor suppressor (blocks G1 to S phase progression)
p53 gene
Barrett's esophagus (chronic GI reflux)
p16 gene
Pale infarcts

17. Lymphoma

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18. Neuroblastoma transcription factor (oncogene)
extrinsic apoptosis
ras gene
Leukocyte extravasation: rolling
N- myc gene

19. Leukemia - lymphoma
smooth muscle benign tumor
blood cell malignant tumors
benign >1 cell type tumor
BRCA1 gene

20. Enzymatic degradation and protein denaturation due to exogenous injury. Inflammatory process where intracellular components extravasate.
TRAP
L- myc gene
CA-125
Necrosis

21. Anaplasia - neoplasia - desmoplasia (fibrous tissue formation in response to neoplasm)
skeletal muscle malignant tumor
alpha - fetoprotein
Second - leading cause of death in the US
Irreversible - plasias

22. Squamous cell carcinoma of skin
smooth muscle malignant tumor
Leading cause of death in the US
Neoplasm associated with actinic keratosis
Free radical eliminators

23. Breast and ovarian cancer 17q tumor suppressor (DNA repair protein)
BRCA1 gene
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)
abl gene
Rb gene

24. Malignant melanoma
p53 gene
Primary tumors that met to bone
dysplastic nevus
DCC gene

25. Burkitt's lymphoma transcription factor (oncogene)
c - myc gene
intrinsic apoptosis
Primary tumors that met to bone
Primary tumors that met to brain

26. Melanoma - basal cell carcinoma - and especially squamous cell carcinomas of the skin.
CEA
immunodeficiency states
Neoplasm associated with xeroderma pigmentosum (albinism)
Alk - phos

27. GIST cytokine receptor (oncogene)
DCC gene
c - kit gene
bone benign tumor
malignant mesenchyme tumor (general)

28. Lung - liver - intestine or following reperfusion.
lung cancer incidence/mortality
Neoplasm associated with xeroderma pigmentosum (albinism)
Second - leading cause of death in the US
Red (hemorrhagic) infarcts

29. Esophagus - stomach
DPC gene
nitrosamines (smoked foods) target
paraneoplastic effects of small cell lung carcinoma
abl gene

30. During embryogenesis - hormone induction and atrophy. Increased mitochondrial permeability and cytochrome c release. Increase Bax (pro - apoptotic) - decreased Bcl -2 (anti - apopotic).
ret gene
intrinsic apoptosis
BRAC2 gene
paraneoplastic effects of small cell lung carcinoma

31. Infections - inflammation - cancer - pregnancy - SLE
causes of increased ESR
CCl4 target
NF1 gene
blood vessels malignant tumor

32. Vascular: ICAM-1 Leukocyte: LFA-1 (integrin)
Leukocyte extravasation: rolling
lung cancer incidence/mortality
erb - B2 gene
Leukocyte extravasation: tight binding

33. Hyperplasia - metaplasia - dysplasia
Reversible - plasias
TRAP
PSA
APC gene

34. Restoration of normal structure - granulation tissue (vascularized + fibrosis) - abscess (fibrosis + pus) - fistula or scarring (collagen).
Resolution of inflammation
secondary amyloidosis (reactive systemic)
dysplastic nevus
c - myc gene

35. Secondary osteosarcoma and fibrosarcoma

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36. Lung (mesothelioma and bronchogenic carcinoma)
BRAC2 gene
Leukocyte extravasation: rolling
Leukocyte extravasation: migration
asbestos target

37. Antibodies to presynaptic Ca2+ channels at NM junction
paraneoplastic effects of thymoma - small cell lung carcinoma
APC gene
aflatoxin target
Second - leading cause of death in the US

38. Membrane lipid peroxidation - protein modification and DNA breakage.
bone malignant tumor
Prostatic acid phosphatase
paraneoplastic effects of small cell lung carcinoma
Free radical cell damage

39. Hemangioma
lung cancer incidence/mortality
smooth muscle benign tumor
BRCA1 gene
blood vessels benign tumor

40. Wilms' tumor 11p tumor suppressor
WT1 gene
abl gene
causes of increased ESR
prostate cancer incidence/mortality

41. Breast - ovarian and gastric carcinomas tyrosine kinase (oncogene)
paraneoplastic effects of small cell lung carcinoma
immunodeficiency states
erb - B2 gene
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants

42. All - AML
Leukocyte extravasation: migration
Neoplasm associated with Down Syndrome
cigarette smoke target
calcitonin

43. Tumor marker: Screen for prostate carcinoma. Can also be elevated in BPH and prostatitis.
c - myc gene
PSA
WT1 gene
paraneoplastic effects of leukemias and lymphomas

44. MEN type II and III tyrosine kinase (oncogene)
acanthosis nigricans (hyperpig and epidermal thickening)
Primary tumors that met to liver
ret gene
paraneoplastic effects of renal cell carcinoma - hemangioblastoma

45. Mature teratoma in women
bone benign tumor
c - kit gene
granulomatous disease
benign >1 cell type tumor

46. Colon>stomach>pancreas>breast>lung (liver and lung are the most common places for mets)
blood vessels malignant tumor
Leukocyte extravasation: migration
Primary tumors that met to liver
CEA

47. Pancreatic cancer (Deleted in Pancreatic Cancer) 18q tumor suppressor
abl gene
Prostatic acid phosphatase
Chronic inflammatory mediators
DPC gene

48. ACTH or ACTH- like peptide
primary amyloidosis
Leukocyte extravasation: rolling
Red (hemorrhagic) infarcts
paraneoplastic effects of small cell lung carcinoma

49. Tumor marker: pancreatic adenocarcinoma
alpha - fetoprotein
Barrett's esophagus (chronic GI reflux)
CA-19-9
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants

50. Squamous cell carcinoma of the esophagus
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)
Colon and rectal cancer incidence
ret gene
NF1 gene