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First Aid Basics

Subjects : health-sciences, first-aid

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Sarcoma
Free radical cell damage
bcl -2 gene
malignant mesenchyme tumor (general)
Bombesin

2. Caused by peroxidation of membrane lipids. Causes acute gastric bleeding and chronic metabolic acidosis and scarring.
iron poisoning
ras gene
benign epithelial tumor
Where you see Psammoma bodies

3. Antibodies to presynaptic Ca2+ channels at NM junction
Free radical eliminators
Reversible - plasias
paraneoplastic effects of thymoma - small cell lung carcinoma
Pale infarcts

4. All - AML
secondary amyloidosis (reactive systemic)
Napthalene (aniline) dyes target
Neoplasm associated with Down Syndrome
Where you see Psammoma bodies

5. Solid tissues with single blood supply. Heart - kidney and spleen.
Pale infarcts
smooth muscle benign tumor
Napthalene (aniline) dyes target
beta - hCG

6. Rhabdomyosarcoma
Leukocyte extravasation: migration
primary amyloidosis
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms
skeletal muscle malignant tumor

7. MEN type II and III tyrosine kinase (oncogene)
Barrett's esophagus (chronic GI reflux)
NF2 gene
Prostatic acid phosphatase
ret gene

8. PECAM-1
Leukocyte extravasation: diapedesis
malignant epithelial tumor
benign epithelial tumor
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms

9. Liver (centrilobular necrosis - fatty change)
Red (hemorrhagic) infarcts
CEA
paraneoplastic effects of thymoma - small cell lung carcinoma
CCl4 target

10. Colon carcinoma GTPase (oncogene)
Red (hemorrhagic) infarcts
AIDS
ras gene
TRAP

11. Anaplasia - neoplasia - desmoplasia (fibrous tissue formation in response to neoplasm)
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)
Irreversible - plasias
ulcerative colitis
Leukocyte extravasation: migration

12. Female 13% Male 12%
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
beta - hCG
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms
Colon and rectal cancer incidence

13. AL
Leukocyte extravasation: diapedesis
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)
Second - leading cause of death in the US
primary amyloidosis

14. During embryogenesis - hormone induction and atrophy. Increased mitochondrial permeability and cytochrome c release. Increase Bax (pro - apoptotic) - decreased Bcl -2 (anti - apopotic).
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)
Napthalene (aniline) dyes target
DCC gene
intrinsic apoptosis

15. Colorectal cancer (assoc with FAP) 5q tumor suppressor
Free radical eliminators
smooth muscle malignant tumor
APC gene
abl gene

16. Enzymes: catalase - superoxide dismutase - glutathione peroxidase.Vitamins: ACE Spontaneous decay
NF2 gene
c - kit gene
Primary tumors that met to liver
Free radical eliminators

17. Lymphoma

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18. Sarcoma - papillary thyroid cancer
radiation exposure
asbestos target
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)
Leukocyte extravasation: rolling

19. Hyperuricemia (excess NA turnover)
aflatoxin target
NF2 gene
paraneoplastic effects of leukemias and lymphomas
Colon and rectal cancer incidence

20. Neutrophils (eos in the gut) - plus other granular leukocytes and antibodies.
skeletal muscle benign tumor
smooth muscle benign tumor
intrinsic apoptosis
Acute inflammatory mediators

21. Colon cancer (Deleted in Colon Cancer) 18q tumor suppressor
DCC gene
WT1 gene
Irreversible - plasias
Leukocyte extravasation: diapedesis

22. GIST cytokine receptor (oncogene)
iron poisoning
smooth muscle benign tumor
Free radical eliminators
c - kit gene

23. Angiosarcoma
skeletal muscle malignant tumor
breast cancer incidence/mortality
blood vessels malignant tumor
fat malignant tumor

24. Hemangioma
asbestos target
extrinsic apoptosis
blood vessels benign tumor
causes of increased ESR

25. Squamous cell carcinoma of skin
Autoimmune (Hashimoto's - myasthenia gravis)
aflatoxin target
CA-125
Neoplasm associated with actinic keratosis

26. Most human cancers - specifically Li - Fraumeni syndrome 17p tumor suppressor (blocks G1 to S phase progression)
iron poisoning
Colon and rectal cancer incidence
p53 gene
Free radical cell damage

27. Vascular: ICAM-1 Leukocyte: LFA-1 (integrin)
p16 gene
Leukocyte extravasation: tight binding
extrinsic apoptosis
Primary tumors that met to brain

28. Erythropoietin
bone malignant tumor
lung cancer incidence/mortality
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)

29. Esophagus - stomach
lung cancer incidence/mortality
Red (hemorrhagic) infarcts
CEA
nitrosamines (smoked foods) target

30. Neuroblastoma transcription factor (oncogene)
asbestos target
Leukocyte extravasation: rolling
Leukocyte extravasation: migration
N- myc gene

31. Tumor marker: prostate carcinoma marker.
WT1 gene
immunodeficiency states
calcitonin
Prostatic acid phosphatase

32. Bacterial products (CLIK):C5a - LTB4 - IL-8 - Kallikrein
Leukocyte extravasation: tight binding
cirrosis (alcohol - hepB or C)
arsenic target
Leukocyte extravasation: migration

33. Tumor marker: carcinoembryonic Ag Very nonspecific
CEA
primary amyloidosis
causes of increased ESR
malignant >1 cell type tumor

34. AA
Paget's bone disease
Free radical cell damage
secondary amyloidosis (reactive systemic)
ret gene

35. Tumor marker: Hydatifiform moles - choriocarcinomas - gestational trophoblastic tumors.
Leukocyte extravasation: rolling
benign epithelial tumor
CCl4 target
beta - hCG

36. Larynx (SqCC) - lung (SqCC and SCC) - kidney (renal cell carcinoma) - bladder (transitional cell carcinoma)
cigarette smoke target
Leukocyte extravasation: migration
Red (hemorrhagic) infarcts
Neoplasm associated with Down Syndrome

37. Bladder (transitional cell carcinoma)
cigarette smoke target
Colon and rectal cancer incidence
Napthalene (aniline) dyes target
lung cancer incidence/mortality

38. Liver (hepatocellular carcinoma)
CA-19-9
BRCA1 gene
aflatoxin target
blood vessels malignant tumor

39. Enzymatic degradation and protein denaturation due to exogenous injury. Inflammatory process where intracellular components extravasate.
abl gene
Alk - phos
Leukocyte extravasation: diapedesis
Necrosis

40. Visceral malignancy (stomach - lung - breast - uterus)
acanthosis nigricans (hyperpig and epidermal thickening)
malignant mesenchyme tumor (general)
paraneoplastic effects of leukemias and lymphomas
Bombesin

41. Secondary osteosarcoma and fibrosarcoma

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42. Lung - breast - skin (melanoma) - kidney (renal cell carcinoma) - GI.50% brain tumors are from mets
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants
granulomatous disease
fat malignant tumor
Primary tumors that met to brain

43. Tumor marker: Screen for prostate carcinoma. Can also be elevated in BPH and prostatitis.
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants
granulomatous disease
PSA
Neoplasm associated with actinic keratosis

44. Hyperplasia - metaplasia - dysplasia
Colon and rectal cancer incidence
Reversible - plasias
Prostatic acid phosphatase
APC gene

45. Breast cancer 13q tumor suppressor (DNA repair protein)
BRAC2 gene
lung cancer incidence/mortality
Prostatic acid phosphatase
smooth muscle benign tumor

46. TB - fungal infections - syphilis - leprosy - cat scratch fever - sarcoid - Crohn's - Berylliosis.
breast cancer incidence/mortality
granulomatous disease
N- myc gene
DCC gene

47. Mature teratoma in women
malignant epithelial tumor
benign >1 cell type tumor
N- myc gene
Barrett's esophagus (chronic GI reflux)

48. Membrane lipid peroxidation - protein modification and DNA breakage.
Paget's bone disease
Free radical cell damage
iron poisoning
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.

49. Skin (SqCC) - liver (angiosarcoma)
primary amyloidosis
arsenic target
bcl -2 gene
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)

50. Leiomyoma
Acute inflammatory mediators
smooth muscle benign tumor
Rb gene
blood vessels malignant tumor