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First Aid Basics

Subjects : health-sciences, first-aid

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Tumor marker: tartrate - resistant acid phosphatase. Hairy cell leukemia (B- cell neoplasm)
Bombesin
TRAP
alpha - fetoprotein
acanthosis nigricans (hyperpig and epidermal thickening)

2. Female 13% Male 12%
Colon and rectal cancer incidence
primary amyloidosis
BRCA1 gene
radiation exposure

3. 32%/13% male
benign >1 cell type tumor
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.
prostate cancer incidence/mortality
granulomatous disease

4. Prostate (blastic) - thyroid - testes - breast (lytic and blastic) - lung (lytic) - kidney (breast and prostate are most common)
immunodeficiency states
dysplastic nevus
Primary tumors that met to bone
CEA

5. Enzymatic degradation and protein denaturation due to exogenous injury. Inflammatory process where intracellular components extravasate.
cirrosis (alcohol - hepB or C)
bcl -2 gene
Necrosis
WT1 gene

6. Tumor marker: pancreatic adenocarcinoma
BRCA1 gene
CA-19-9
L- myc gene
cirrosis (alcohol - hepB or C)

7. Female 13%/23% and rising Male 16%/33% (mortality has plateaued)
paraneoplastic effects of small cell lung carcinoma
Primary tumors that met to bone
Leading cause of death in the US
lung cancer incidence/mortality

8. Antibodies to presynaptic Ca2+ channels at NM junction
paraneoplastic effects of thymoma - small cell lung carcinoma
aflatoxin target
benign epithelial tumor
CCl4 target

9. Squamous cell carcinoma of the esophagus
fat malignant tumor
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)
L- myc gene
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)

10. Melanoma 9p tumor suppressor
Leukocyte extravasation: migration
lung cancer incidence/mortality
p16 gene
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)

11. Blood (leukemia)
Barrett's esophagus (chronic GI reflux)
Alkylating agents target
Second - leading cause of death in the US
cirrosis (alcohol - hepB or C)

12. Esophagus - stomach
nitrosamines (smoked foods) target
cirrosis (alcohol - hepB or C)
malignant mesenchyme tumor (general)
beta - hCG

13. CML tyrosine kinase (oncogene)
smooth muscle benign tumor
fat malignant tumor
Pale infarcts
abl gene

14. Anaplasia - neoplasia - desmoplasia (fibrous tissue formation in response to neoplasm)
Red (hemorrhagic) infarcts
Bombesin
asbestos target
Irreversible - plasias

15. All - AML
N- myc gene
asbestos target
Neoplasm associated with Down Syndrome
Autoimmune (Hashimoto's - myasthenia gravis)

16. Sickle cell (altered shape) - polycythemia (too many) - CHF (unknown)
CCl4 target
causes of decreased ESR
fat malignant tumor
c - kit gene

17. AL
iron poisoning
BRCA1 gene
L- myc gene
primary amyloidosis

18. Neurofibromatosis type 2 22q tumor suppressor (key type 2=22)
Barrett's esophagus (chronic GI reflux)
NF2 gene
arsenic target
TRAP

19. Colorectal cancer (assoc with FAP) 5q tumor suppressor
Prostatic acid phosphatase
APC gene
Barrett's esophagus (chronic GI reflux)
CCl4 target

20. Secondary osteosarcoma and fibrosarcoma

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21. Tumor marker: thyroid medullary carcinoma
S-100
causes of decreased ESR
calcitonin
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.

22. Larynx (SqCC) - lung (SqCC and SCC) - kidney (renal cell carcinoma) - bladder (transitional cell carcinoma)
cigarette smoke target
Rb gene
Where you see Psammoma bodies
ulcerative colitis

23. Retinoblastoma - osteosarcoma 13q tumor suppressor (blocks G1 to S phase progression)
Rb gene
Neoplasm associated with actinic keratosis
malignant epithelial tumor
N- myc gene

24. Breast - ovarian and gastric carcinomas tyrosine kinase (oncogene)
Free radical eliminators
NF2 gene
Neoplasm associated with actinic keratosis
erb - B2 gene

25. Colon carcinoma GTPase (oncogene)
nitrosamines (smoked foods) target
ras gene
Primary tumors that met to brain
TRAP

26. AA
secondary amyloidosis (reactive systemic)
aflatoxin target
Irreversible - plasias
Bombesin

27. Mature teratoma in women
Barrett's esophagus (chronic GI reflux)
Neoplasm associated with Down Syndrome
breast cancer incidence/mortality
benign >1 cell type tumor

28. Membrane lipid peroxidation - protein modification and DNA breakage.
bone benign tumor
Irreversible - plasias
Free radical cell damage
Acute inflammatory mediators

29. Enzymes: catalase - superoxide dismutase - glutathione peroxidase.Vitamins: ACE Spontaneous decay
c - kit gene
Prostatic acid phosphatase
Free radical eliminators
lung cancer incidence/mortality

30. Sarcoma
S-100
secondary amyloidosis (reactive systemic)
malignant mesenchyme tumor (general)
N- myc gene

31. Tumor marker: Hydatifiform moles - choriocarcinomas - gestational trophoblastic tumors.
beta - hCG
BRAC2 gene
CA-19-9
ret gene

32. Erythropoietin
c - kit gene
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
Autoimmune (Hashimoto's - myasthenia gravis)
breast cancer incidence/mortality

33. Heart disease
Reversible - plasias
Neoplasm associated with Down Syndrome
primary amyloidosis
Leading cause of death in the US

34. Solid tissues with single blood supply. Heart - kidney and spleen.
ras gene
c - kit gene
Pale infarcts
immunodeficiency states

35. Esophageal adenocarcinoma

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36. Tumor marker: ovarian - malignant epithelial tumors.
CA-125
acanthosis nigricans (hyperpig and epidermal thickening)
ret gene
APC gene

37. Leiomyosarcoma
smooth muscle malignant tumor
breast cancer incidence/mortality
Second - leading cause of death in the US
bone benign tumor

38. Gastric adenocacinoma
c - myc gene
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants
malignant epithelial tumor
Where you see Psammoma bodies

39. Melanoma - basal cell carcinoma - and especially squamous cell carcinomas of the skin.
paraneoplastic effects of leukemias and lymphomas
Irreversible - plasias
Alk - phos
Neoplasm associated with xeroderma pigmentosum (albinism)

40. Liver (angiosarcoma)
vinyl chloride target
alpha - fetoprotein
cirrosis (alcohol - hepB or C)
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.

41. Leiomyoma
Acute inflammatory mediators
smooth muscle benign tumor
calcitonin
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)

42. Neutrophils (eos in the gut) - plus other granular leukocytes and antibodies.
Acute inflammatory mediators
Alk - phos
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants
Napthalene (aniline) dyes target

43. Tumor marker: Screen for prostate carcinoma. Can also be elevated in BPH and prostatitis.
Second - leading cause of death in the US
PSA
p16 gene
Free radical eliminators

44. During embryogenesis - hormone induction and atrophy. Increased mitochondrial permeability and cytochrome c release. Increase Bax (pro - apoptotic) - decreased Bcl -2 (anti - apopotic).
malignant mesenchyme tumor (general)
acanthosis nigricans (hyperpig and epidermal thickening)
intrinsic apoptosis
nitrosamines (smoked foods) target

45. Neuroblastoma transcription factor (oncogene)
NF2 gene
Alkylating agents target
c - kit gene
N- myc gene

46. Rhabdomyosarcoma
Barrett's esophagus (chronic GI reflux)
paraneoplastic effects of leukemias and lymphomas
acanthosis nigricans (hyperpig and epidermal thickening)
skeletal muscle malignant tumor

47. Lung tumor transcription factor (oncogene)
Irreversible - plasias
L- myc gene
ulcerative colitis
alpha - fetoprotein

48. Breast cancer 13q tumor suppressor (DNA repair protein)
blood cell malignant tumors
ras gene
Neoplasm associated with actinic keratosis
BRAC2 gene

49. Tumor marker: prostate carcinoma marker.
Leukocyte extravasation: tight binding
Prostatic acid phosphatase
blood vessels benign tumor
bone malignant tumor

50. Adenocarcinoma - papillary carcinoma
malignant epithelial tumor
APC gene
Reversible - plasias
secondary amyloidosis (reactive systemic)

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First Aid Basics

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