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First Aid Basics

Subjects : health-sciences, first-aid

Instructions:

Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can study here.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Visceral malignancy (stomach - lung - breast - uterus)
causes of increased ESR
acanthosis nigricans (hyperpig and epidermal thickening)
abl gene
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.

2. Most human cancers - specifically Li - Fraumeni syndrome 17p tumor suppressor (blocks G1 to S phase progression)
acanthosis nigricans (hyperpig and epidermal thickening)
lung cancer incidence/mortality
paraneoplastic effects of leukemias and lymphomas
p53 gene

3. ADH
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms
blood cell malignant tumors
AIDS
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)

4. Malignant lymphoma
immunodeficiency states
p53 gene
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants
abl gene

5. Lung - liver - intestine or following reperfusion.
Red (hemorrhagic) infarcts
arsenic target
fat malignant tumor
Acute inflammatory mediators

6. Esophageal adenocarcinoma

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7. Angiosarcoma
erb - B2 gene
WT1 gene
Leukocyte extravasation: migration
blood vessels malignant tumor

8. Neutrophils (eos in the gut) - plus other granular leukocytes and antibodies.
breast cancer incidence/mortality
Acute inflammatory mediators
blood vessels benign tumor
bone malignant tumor

9. Liposarcoma
Second - leading cause of death in the US
DCC gene
fat malignant tumor
ulcerative colitis

10. Neurofibromatosis type 2 22q tumor suppressor (key type 2=22)
NF2 gene
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)
Napthalene (aniline) dyes target
Primary tumors that met to brain

11. Retinoblastoma - osteosarcoma 13q tumor suppressor (blocks G1 to S phase progression)
causes of increased ESR
asbestos target
intrinsic apoptosis
Rb gene

12. Leiomyosarcoma
Neoplasm associated with actinic keratosis
Pale infarcts
smooth muscle malignant tumor
Bombesin

13. Melanoma 9p tumor suppressor
p16 gene
bone malignant tumor
smooth muscle malignant tumor
Acute inflammatory mediators

14. GIST cytokine receptor (oncogene)
Pale infarcts
Second - leading cause of death in the US
c - kit gene
PSA

15. Follicular and undifferentiated lymphomas anti - apoptotic molecule (oncogene)
Necrosis
bcl -2 gene
granulomatous disease
Irreversible - plasias

16. Bacterial products (CLIK):C5a - LTB4 - IL-8 - Kallikrein
calcitonin
Leukocyte extravasation: migration
BRCA1 gene
CA-19-9

17. Wilms' tumor 11p tumor suppressor
Irreversible - plasias
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms
Where you see Psammoma bodies
WT1 gene

18. MEN type II and III tyrosine kinase (oncogene)
radiation exposure
prostate cancer incidence/mortality
ret gene
benign >1 cell type tumor

19. Lipoma
benign epithelial tumor
malignant epithelial tumor
nitrosamines (smoked foods) target
fat benign tumor

20. Membrane lipid peroxidation - protein modification and DNA breakage.
DPC gene
Free radical cell damage
Where you see Psammoma bodies
causes of decreased ESR

21. Anaplasia - neoplasia - desmoplasia (fibrous tissue formation in response to neoplasm)
smooth muscle benign tumor
p53 gene
Neoplasm associated with actinic keratosis
Irreversible - plasias

22. Rhabdomyoma
skeletal muscle benign tumor
granulomatous disease
TRAP
Second - leading cause of death in the US

23. Tumor marker: (Normal in fetus). Hepatocellular carcinomas. Nonseminomatous germ cell tumors of the testis.
N- myc gene
alpha - fetoprotein
Leading cause of death in the US
Colon and rectal cancer incidence

24. Solid tissues with single blood supply. Heart - kidney and spleen.
Pale infarcts
Red (hemorrhagic) infarcts
S-100
alpha - fetoprotein

25. Female 13% Male 12%
Alkylating agents target
Colon and rectal cancer incidence
paraneoplastic effects of small cell lung carcinoma
paraneoplastic effects of renal cell carcinoma - hemangioblastoma

26. Neuroblastoma transcription factor (oncogene)
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms
Paget's bone disease
N- myc gene
S-100

27. Antibodies to presynaptic Ca2+ channels at NM junction
paraneoplastic effects of thymoma - small cell lung carcinoma
CCl4 target
radiation exposure
PSA

28. Blood (leukemia)
p16 gene
arsenic target
Alkylating agents target
Neoplasm associated with actinic keratosis

29. Liver (angiosarcoma)
vinyl chloride target
skeletal muscle malignant tumor
L- myc gene
BRCA1 gene

30. Leukemia - lymphoma
lung cancer incidence/mortality
blood cell malignant tumors
Colon and rectal cancer incidence
WT1 gene

31. Tumor marker: neuroblastoma - lung and gastric cancer
iron poisoning
Bombesin
breast cancer incidence/mortality
bcl -2 gene

32. Liver (hepatocellular carcinoma)
Second - leading cause of death in the US
prostate cancer incidence/mortality
breast cancer incidence/mortality
aflatoxin target

33. Neurofibromatosis type 1 17q tumor suppressor
Primary tumors that met to brain
ras gene
nitrosamines (smoked foods) target
NF1 gene

34. Enzymatic degradation and protein denaturation due to exogenous injury. Inflammatory process where intracellular components extravasate.
ret gene
Necrosis
Chronic inflammatory mediators
APC gene

35. Tumor marker: melanoma - neural tumors - astrocytomas
S-100
Leukocyte extravasation: tight binding
vinyl chloride target
PSA

36. Tumor marker: ovarian - malignant epithelial tumors.
immunodeficiency states
ulcerative colitis
extrinsic apoptosis
CA-125

37. Breast cancer 13q tumor suppressor (DNA repair protein)
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
BRAC2 gene
smooth muscle benign tumor
S-100

38. Vascular: ICAM-1 Leukocyte: LFA-1 (integrin)
bone malignant tumor
benign >1 cell type tumor
Leukocyte extravasation: tight binding
smooth muscle malignant tumor

39. CML tyrosine kinase (oncogene)
dysplastic nevus
ulcerative colitis
abl gene
Pale infarcts

40. Colon carcinoma GTPase (oncogene)
arsenic target
primary amyloidosis
beta - hCG
ras gene

41. Pancreatic cancer (Deleted in Pancreatic Cancer) 18q tumor suppressor
Autoimmune (Hashimoto's - myasthenia gravis)
Bombesin
skeletal muscle benign tumor
DPC gene

42. Tumor marker: thyroid medullary carcinoma
calcitonin
iron poisoning
CEA
bone malignant tumor

43. Squamous cell carcinoma of the esophagus
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)
Second - leading cause of death in the US
Prostatic acid phosphatase
fat benign tumor

44. Lymphoma

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45. Lung - breast - skin (melanoma) - kidney (renal cell carcinoma) - GI.50% brain tumors are from mets
iron poisoning
immunodeficiency states
Primary tumors that met to brain
cigarette smoke target

46. Colon>stomach>pancreas>breast>lung (liver and lung are the most common places for mets)
Necrosis
cigarette smoke target
Where you see Psammoma bodies
Primary tumors that met to liver

47. All - AML
Leukocyte extravasation: rolling
Second - leading cause of death in the US
Neoplasm associated with Down Syndrome
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms

48. Leiomyoma
blood vessels benign tumor
CA-19-9
fat malignant tumor
smooth muscle benign tumor

49. Secondary osteosarcoma and fibrosarcoma

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50. Hyperuricemia (excess NA turnover)
smooth muscle malignant tumor
paraneoplastic effects of leukemias and lymphomas
Necrosis
Leukocyte extravasation: rolling