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First Aid Basics

Subjects : health-sciences, first-aid

Instructions:

Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can study here.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Sarcoma - papillary thyroid cancer
radiation exposure
Free radical cell damage
Irreversible - plasias
iron poisoning

2. Bladder (transitional cell carcinoma)
ret gene
Resolution of inflammation
Napthalene (aniline) dyes target
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)

3. Tumor marker: tartrate - resistant acid phosphatase. Hairy cell leukemia (B- cell neoplasm)
TRAP
Leukocyte extravasation: rolling
S-100
malignant >1 cell type tumor

4. Astrocytoma - angiomyolipoma - cardiac rhabdomyoma
APC gene
Leukocyte extravasation: migration
Primary tumors that met to brain
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)

5. Secondary osteosarcoma and fibrosarcoma

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6. Osteosarcoma
acanthosis nigricans (hyperpig and epidermal thickening)
bone malignant tumor
CEA
erb - B2 gene

7. Breast cancer 13q tumor suppressor (DNA repair protein)
BRAC2 gene
DPC gene
L- myc gene
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.

8. Wilms' tumor 11p tumor suppressor
WT1 gene
smooth muscle malignant tumor
Acute inflammatory mediators
ulcerative colitis

9. Colon carcinoma GTPase (oncogene)
aflatoxin target
fat malignant tumor
ras gene
malignant >1 cell type tumor

10. Visceral malignancy (stomach - lung - breast - uterus)
Primary tumors that met to liver
Reversible - plasias
abl gene
acanthosis nigricans (hyperpig and epidermal thickening)

11. Neuroblastoma transcription factor (oncogene)
Where you see Psammoma bodies
Alkylating agents target
nitrosamines (smoked foods) target
N- myc gene

12. Liver (angiosarcoma)
Neoplasm associated with Down Syndrome
primary amyloidosis
smooth muscle benign tumor
vinyl chloride target

13. TB - fungal infections - syphilis - leprosy - cat scratch fever - sarcoid - Crohn's - Berylliosis.
CA-125
immunodeficiency states
benign >1 cell type tumor
granulomatous disease

14. Mature teratoma in women
erb - B2 gene
fat benign tumor
benign >1 cell type tumor
Prostatic acid phosphatase

15. Bacterial products (CLIK):C5a - LTB4 - IL-8 - Kallikrein
paraneoplastic effects of thymoma - small cell lung carcinoma
Acute inflammatory mediators
L- myc gene
Leukocyte extravasation: migration

16. Tumor marker: (Normal in fetus). Hepatocellular carcinomas. Nonseminomatous germ cell tumors of the testis.
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)
alpha - fetoprotein
Reversible - plasias
smooth muscle benign tumor

17. Osteoma
blood vessels benign tumor
Neoplasm associated with actinic keratosis
bone benign tumor
arsenic target

18. Follicular and undifferentiated lymphomas anti - apoptotic molecule (oncogene)
Leading cause of death in the US
c - myc gene
bcl -2 gene
Rb gene

19. Caused by peroxidation of membrane lipids. Causes acute gastric bleeding and chronic metabolic acidosis and scarring.
iron poisoning
blood cell malignant tumors
nitrosamines (smoked foods) target
Pale infarcts

20. Pancreatic cancer (Deleted in Pancreatic Cancer) 18q tumor suppressor
DPC gene
benign epithelial tumor
ras gene
alpha - fetoprotein

21. Rhabdomyosarcoma
Alk - phos
skeletal muscle malignant tumor
Leukocyte extravasation: diapedesis
paraneoplastic effects of thymoma - small cell lung carcinoma

22. Hyperuricemia (excess NA turnover)
paraneoplastic effects of leukemias and lymphomas
ras gene
blood vessels benign tumor
WT1 gene

23. Squamous cell carcinoma of the esophagus
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)
bcl -2 gene
Primary tumors that met to liver
breast cancer incidence/mortality

24. Colonic adenocarcinoma
Red (hemorrhagic) infarcts
ulcerative colitis
malignant >1 cell type tumor
CCl4 target

25. During embryogenesis - hormone induction and atrophy. Increased mitochondrial permeability and cytochrome c release. Increase Bax (pro - apoptotic) - decreased Bcl -2 (anti - apopotic).
vinyl chloride target
PSA
extrinsic apoptosis
intrinsic apoptosis

26. Esophageal adenocarcinoma

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27. Enzymes: catalase - superoxide dismutase - glutathione peroxidase.Vitamins: ACE Spontaneous decay
Leading cause of death in the US
Free radical eliminators
ras gene
Primary tumors that met to brain

28. ADH
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms
Bombesin
NF2 gene
blood cell malignant tumors

29. Papillary (thyroid) - Serous (ovary) - Meningioma - Mesothelioma
Where you see Psammoma bodies
skeletal muscle malignant tumor
primary amyloidosis
Resolution of inflammation

30. Antibodies to presynaptic Ca2+ channels at NM junction
paraneoplastic effects of thymoma - small cell lung carcinoma
Alkylating agents target
bone malignant tumor
arsenic target

31. Malignant melanoma
dysplastic nevus
p16 gene
Neoplasm associated with xeroderma pigmentosum (albinism)
causes of decreased ESR

32. Colon>stomach>pancreas>breast>lung (liver and lung are the most common places for mets)
Free radical cell damage
Primary tumors that met to liver
Napthalene (aniline) dyes target
lung cancer incidence/mortality

33. Rhabdomyoma
BRAC2 gene
blood vessels malignant tumor
skeletal muscle benign tumor
iron poisoning

34. Lung tumor transcription factor (oncogene)
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.
ret gene
L- myc gene
iron poisoning

35. Squamous cell carcinoma of skin
Neoplasm associated with actinic keratosis
extrinsic apoptosis
TRAP
secondary amyloidosis (reactive systemic)

36. Membrane lipid peroxidation - protein modification and DNA breakage.
smooth muscle benign tumor
Free radical cell damage
Primary tumors that met to brain
AIDS

37. Hepatocellular carcinoma
DCC gene
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants
cirrosis (alcohol - hepB or C)
skeletal muscle benign tumor

38. Neurofibromatosis type 2 22q tumor suppressor (key type 2=22)
paraneoplastic effects of thymoma - small cell lung carcinoma
benign epithelial tumor
S-100
NF2 gene

39. Tumor marker: Hydatifiform moles - choriocarcinomas - gestational trophoblastic tumors.
lung cancer incidence/mortality
beta - hCG
Free radical cell damage
Neoplasm associated with actinic keratosis

40. CML tyrosine kinase (oncogene)
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
BRCA1 gene
abl gene
prostate cancer incidence/mortality

41. Tumor marker: ovarian - malignant epithelial tumors.
arsenic target
CA-125
c - kit gene
blood cell malignant tumors

42. Prostate (blastic) - thyroid - testes - breast (lytic and blastic) - lung (lytic) - kidney (breast and prostate are most common)
Necrosis
Primary tumors that met to bone
cigarette smoke target
calcitonin

43. Hyperplasia - metaplasia - dysplasia
Reversible - plasias
paraneoplastic effects of leukemias and lymphomas
DPC gene
skeletal muscle malignant tumor

44. Solid tissues with single blood supply. Heart - kidney and spleen.
lung cancer incidence/mortality
Free radical cell damage
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.
Pale infarcts

45. Lymphoma

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46. Most human cancers - specifically Li - Fraumeni syndrome 17p tumor suppressor (blocks G1 to S phase progression)
p53 gene
Primary tumors that met to brain
abl gene
S-100

47. Tumor marker: mets to bone - obstructive biliary disease - Paget's
BRCA1 gene
Autoimmune (Hashimoto's - myasthenia gravis)
Alk - phos
Neoplasm associated with xeroderma pigmentosum (albinism)

48. Hemangioma
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
N- myc gene
blood vessels benign tumor
extrinsic apoptosis

49. 32%/18% female
Leukocyte extravasation: diapedesis
breast cancer incidence/mortality
L- myc gene
DPC gene

50. PECAM-1
Irreversible - plasias
Leukocyte extravasation: diapedesis
benign epithelial tumor
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)