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First Aid Basics

Subjects : health-sciences, first-aid

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Sarcoma - papillary thyroid cancer
Necrosis
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)
radiation exposure
skeletal muscle malignant tumor

2. Liposarcoma
Second - leading cause of death in the US
fat malignant tumor
fat benign tumor
bone benign tumor

3. Tumor marker: ovarian - malignant epithelial tumors.
CA-125
p16 gene
asbestos target
c - myc gene

4. Hyperplasia - metaplasia - dysplasia
Where you see Psammoma bodies
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms
Reversible - plasias
smooth muscle benign tumor

5. Breast cancer 13q tumor suppressor (DNA repair protein)
BRAC2 gene
c - myc gene
p53 gene
Second - leading cause of death in the US

6. Colorectal cancer (assoc with FAP) 5q tumor suppressor
Paget's bone disease
Chronic inflammatory mediators
CA-19-9
APC gene

7. Membrane lipid peroxidation - protein modification and DNA breakage.
Free radical cell damage
skeletal muscle malignant tumor
causes of decreased ESR
Leading cause of death in the US

8. Infections - inflammation - cancer - pregnancy - SLE
causes of increased ESR
beta - hCG
smooth muscle benign tumor
dysplastic nevus

9. Neuroblastoma transcription factor (oncogene)
Free radical eliminators
CA-125
N- myc gene
Resolution of inflammation

10. Melanoma - basal cell carcinoma - and especially squamous cell carcinomas of the skin.
nitrosamines (smoked foods) target
erb - B2 gene
Neoplasm associated with xeroderma pigmentosum (albinism)
fat benign tumor

11. Lipoma
fat malignant tumor
ras gene
fat benign tumor
secondary amyloidosis (reactive systemic)

12. Caused by peroxidation of membrane lipids. Causes acute gastric bleeding and chronic metabolic acidosis and scarring.
iron poisoning
paraneoplastic effects of small cell lung carcinoma
immunodeficiency states
BRAC2 gene

13. CML tyrosine kinase (oncogene)
abl gene
c - kit gene
malignant mesenchyme tumor (general)
fat malignant tumor

14. All - AML
Primary tumors that met to liver
Neoplasm associated with Down Syndrome
Leukocyte extravasation: tight binding
PSA

15. PTH- related peptide - TGF- beta - TNF - IL-1
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.
Free radical cell damage
benign epithelial tumor
fat benign tumor

16. Gastric adenocacinoma
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants
extrinsic apoptosis
Leukocyte extravasation: rolling
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms

17. Antibodies to presynaptic Ca2+ channels at NM junction
primary amyloidosis
Napthalene (aniline) dyes target
Leukocyte extravasation: rolling
paraneoplastic effects of thymoma - small cell lung carcinoma

18. Lung - breast - skin (melanoma) - kidney (renal cell carcinoma) - GI.50% brain tumors are from mets
Primary tumors that met to brain
nitrosamines (smoked foods) target
primary amyloidosis
benign >1 cell type tumor

19. Blood (leukemia)
p53 gene
Neoplasm associated with xeroderma pigmentosum (albinism)
Alkylating agents target
calcitonin

20. Liver (angiosarcoma)
nitrosamines (smoked foods) target
Leukocyte extravasation: diapedesis
Paget's bone disease
vinyl chloride target

21. Adenocarcinoma - papillary carcinoma
Chronic inflammatory mediators
arsenic target
Colon and rectal cancer incidence
malignant epithelial tumor

22. Pancreatic cancer (Deleted in Pancreatic Cancer) 18q tumor suppressor
Prostatic acid phosphatase
DPC gene
acanthosis nigricans (hyperpig and epidermal thickening)
CEA

23. Mature teratoma in men or malignant teratoma in M/F
Bombesin
Leukocyte extravasation: diapedesis
c - kit gene
malignant >1 cell type tumor

24. Hyperuricemia (excess NA turnover)
paraneoplastic effects of leukemias and lymphomas
fat benign tumor
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms
CEA

25. Lung (mesothelioma and bronchogenic carcinoma)
aflatoxin target
bone benign tumor
asbestos target
DPC gene

26. Visceral malignancy (stomach - lung - breast - uterus)
Bombesin
intrinsic apoptosis
blood vessels malignant tumor
acanthosis nigricans (hyperpig and epidermal thickening)

27. Follicular and undifferentiated lymphomas anti - apoptotic molecule (oncogene)
c - myc gene
Leading cause of death in the US
bcl -2 gene
Neoplasm associated with actinic keratosis

28. Adenoma - papilloma
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.
BRAC2 gene
prostate cancer incidence/mortality
benign epithelial tumor

29. Liver (hepatocellular carcinoma)
asbestos target
Rb gene
aflatoxin target
secondary amyloidosis (reactive systemic)

30. Leukemia - lymphoma
blood cell malignant tumors
benign epithelial tumor
Alk - phos
breast cancer incidence/mortality

31. 32%/13% male
prostate cancer incidence/mortality
TRAP
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)

32. Prostate (blastic) - thyroid - testes - breast (lytic and blastic) - lung (lytic) - kidney (breast and prostate are most common)
nitrosamines (smoked foods) target
blood vessels malignant tumor
Second - leading cause of death in the US
Primary tumors that met to bone

33. Tumor marker: (Normal in fetus). Hepatocellular carcinomas. Nonseminomatous germ cell tumors of the testis.
benign epithelial tumor
Primary tumors that met to brain
APC gene
alpha - fetoprotein

34. Lung tumor transcription factor (oncogene)
Autoimmune (Hashimoto's - myasthenia gravis)
Neoplasm associated with actinic keratosis
L- myc gene
DCC gene

35. 32%/18% female
blood cell malignant tumors
benign epithelial tumor
breast cancer incidence/mortality
c - kit gene

36. Rhabdomyosarcoma
bcl -2 gene
skeletal muscle malignant tumor
acanthosis nigricans (hyperpig and epidermal thickening)
Neoplasm associated with xeroderma pigmentosum (albinism)

37. Breast - ovarian and gastric carcinomas tyrosine kinase (oncogene)
cigarette smoke target
Rb gene
erb - B2 gene
arsenic target

38. Solid tissues with single blood supply. Heart - kidney and spleen.
ras gene
Pale infarcts
paraneoplastic effects of small cell lung carcinoma
blood cell malignant tumors

39. Lung - liver - intestine or following reperfusion.
lung cancer incidence/mortality
aflatoxin target
blood vessels malignant tumor
Red (hemorrhagic) infarcts

40. ADH
smooth muscle malignant tumor
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms
Leukocyte extravasation: diapedesis
CEA

41. Astrocytoma - angiomyolipoma - cardiac rhabdomyoma
vinyl chloride target
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)
radiation exposure
aflatoxin target

42. Melanoma 9p tumor suppressor
vinyl chloride target
intrinsic apoptosis
p16 gene
paraneoplastic effects of renal cell carcinoma - hemangioblastoma

43. Leiomyoma
WT1 gene
smooth muscle benign tumor
iron poisoning
acanthosis nigricans (hyperpig and epidermal thickening)

44. Neurofibromatosis type 2 22q tumor suppressor (key type 2=22)
NF2 gene
primary amyloidosis
BRAC2 gene
Paget's bone disease

45. Lymphoma

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46. Rhabdomyoma
Leukocyte extravasation: rolling
Primary tumors that met to bone
bone benign tumor
skeletal muscle benign tumor

47. MEN type II and III tyrosine kinase (oncogene)
malignant mesenchyme tumor (general)
Alk - phos
ret gene
Rb gene

48. Ligand - receptor interactions. Release of perforin and granzyme B.
DCC gene
extrinsic apoptosis
Reversible - plasias
breast cancer incidence/mortality

49. Anaplasia - neoplasia - desmoplasia (fibrous tissue formation in response to neoplasm)
Irreversible - plasias
causes of increased ESR
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)
smooth muscle malignant tumor

50. Malignant lymphoma
Alkylating agents target
Acute inflammatory mediators
immunodeficiency states
APC gene

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First Aid Basics

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