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Test your basic knowledge |
First Aid Basics
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Gastric adenocacinoma
L- myc gene
Free radical cell damage
bone malignant tumor
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants
2. Squamous cell carcinoma of the esophagus
TRAP
Red (hemorrhagic) infarcts
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)
Alk - phos
3. Liver (angiosarcoma)
lung cancer incidence/mortality
Leading cause of death in the US
vinyl chloride target
cigarette smoke target
4. TB - fungal infections - syphilis - leprosy - cat scratch fever - sarcoid - Crohn's - Berylliosis.
smooth muscle benign tumor
paraneoplastic effects of thymoma - small cell lung carcinoma
granulomatous disease
benign >1 cell type tumor
5. During embryogenesis - hormone induction and atrophy. Increased mitochondrial permeability and cytochrome c release. Increase Bax (pro - apoptotic) - decreased Bcl -2 (anti - apopotic).
intrinsic apoptosis
malignant >1 cell type tumor
AIDS
Alkylating agents target
6. Visceral malignancy (stomach - lung - breast - uterus)
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.
ulcerative colitis
acanthosis nigricans (hyperpig and epidermal thickening)
BRCA1 gene
7. 32%/18% female
immunodeficiency states
ulcerative colitis
breast cancer incidence/mortality
AIDS
8. Female 13% Male 12%
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms
alpha - fetoprotein
Colon and rectal cancer incidence
extrinsic apoptosis
9. ACTH or ACTH- like peptide
BRAC2 gene
asbestos target
paraneoplastic effects of small cell lung carcinoma
calcitonin
10. Prostate (blastic) - thyroid - testes - breast (lytic and blastic) - lung (lytic) - kidney (breast and prostate are most common)
Autoimmune (Hashimoto's - myasthenia gravis)
Leading cause of death in the US
PSA
Primary tumors that met to bone
11. Breast - ovarian and gastric carcinomas tyrosine kinase (oncogene)
CA-19-9
benign epithelial tumor
erb - B2 gene
skeletal muscle benign tumor
12. Ligand - receptor interactions. Release of perforin and granzyme B.
Free radical eliminators
iron poisoning
acanthosis nigricans (hyperpig and epidermal thickening)
extrinsic apoptosis
13. Colonic adenocarcinoma
APC gene
lung cancer incidence/mortality
ulcerative colitis
Where you see Psammoma bodies
14. Bacterial products (CLIK):C5a - LTB4 - IL-8 - Kallikrein
Chronic inflammatory mediators
Leukocyte extravasation: migration
CCl4 target
ras gene
15. Lung - liver - intestine or following reperfusion.
CA-19-9
Red (hemorrhagic) infarcts
Necrosis
bone benign tumor
16. Tumor marker: pancreatic adenocarcinoma
CA-19-9
cirrosis (alcohol - hepB or C)
bcl -2 gene
S-100
17. Hyperplasia - metaplasia - dysplasia
Reversible - plasias
vinyl chloride target
bone malignant tumor
acanthosis nigricans (hyperpig and epidermal thickening)
18. Colon carcinoma GTPase (oncogene)
smooth muscle malignant tumor
p53 gene
ras gene
asbestos target
19. Infections - inflammation - cancer - pregnancy - SLE
benign epithelial tumor
Primary tumors that met to brain
causes of increased ESR
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)
20. Liposarcoma
fat malignant tumor
blood cell malignant tumors
CEA
Primary tumors that met to brain
21. Neurofibromatosis type 2 22q tumor suppressor (key type 2=22)
arsenic target
bone malignant tumor
NF2 gene
c - myc gene
22. Melanoma - basal cell carcinoma - and especially squamous cell carcinomas of the skin.
dysplastic nevus
Neoplasm associated with xeroderma pigmentosum (albinism)
causes of decreased ESR
L- myc gene
23. Rhabdomyosarcoma
extrinsic apoptosis
nitrosamines (smoked foods) target
skeletal muscle malignant tumor
c - kit gene
24. Osteosarcoma
NF2 gene
Paget's bone disease
alpha - fetoprotein
bone malignant tumor
25. Tumor marker: Screen for prostate carcinoma. Can also be elevated in BPH and prostatitis.
PSA
vinyl chloride target
DPC gene
cirrosis (alcohol - hepB or C)
26. Leukemia - lymphoma
BRCA1 gene
blood cell malignant tumors
Napthalene (aniline) dyes target
blood vessels benign tumor
27. Hyperuricemia (excess NA turnover)
blood vessels malignant tumor
blood vessels benign tumor
Bombesin
paraneoplastic effects of leukemias and lymphomas
28. Tumor marker: melanoma - neural tumors - astrocytomas
S-100
Paget's bone disease
ret gene
alpha - fetoprotein
29. 32%/13% male
Leukocyte extravasation: tight binding
skeletal muscle malignant tumor
prostate cancer incidence/mortality
NF1 gene
30. Enzymatic degradation and protein denaturation due to exogenous injury. Inflammatory process where intracellular components extravasate.
Second - leading cause of death in the US
ulcerative colitis
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.
Necrosis
31. Erythropoietin
primary amyloidosis
Chronic inflammatory mediators
immunodeficiency states
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
32. Liver (centrilobular necrosis - fatty change)
beta - hCG
paraneoplastic effects of thymoma - small cell lung carcinoma
CCl4 target
cigarette smoke target
33. Malignant melanoma
nitrosamines (smoked foods) target
Alkylating agents target
dysplastic nevus
aflatoxin target
34. Vascular: E and P- selectin Leukocyte: Sialyl Lewis
Leukocyte extravasation: rolling
L- myc gene
Primary tumors that met to brain
paraneoplastic effects of leukemias and lymphomas
35. Angiosarcoma
fat malignant tumor
asbestos target
ras gene
blood vessels malignant tumor
36. Enzymes: catalase - superoxide dismutase - glutathione peroxidase.Vitamins: ACE Spontaneous decay
breast cancer incidence/mortality
Free radical eliminators
Napthalene (aniline) dyes target
lung cancer incidence/mortality
37. All - AML
L- myc gene
Leading cause of death in the US
Neoplasm associated with Down Syndrome
nitrosamines (smoked foods) target
38. Breast cancer 13q tumor suppressor (DNA repair protein)
BRAC2 gene
breast cancer incidence/mortality
fat malignant tumor
L- myc gene
39. Colon>stomach>pancreas>breast>lung (liver and lung are the most common places for mets)
Leukocyte extravasation: migration
Primary tumors that met to liver
granulomatous disease
c - kit gene
40. Esophagus - stomach
malignant >1 cell type tumor
causes of increased ESR
nitrosamines (smoked foods) target
p53 gene
41. Aggressive malignant lymphomas (non - Hodgkin's) and Kaposi's sarcoma
TRAP
Bombesin
APC gene
AIDS
42. Sarcoma - papillary thyroid cancer
benign epithelial tumor
Second - leading cause of death in the US
radiation exposure
causes of increased ESR
43. Osteoma
vinyl chloride target
bone benign tumor
Primary tumors that met to liver
secondary amyloidosis (reactive systemic)
44. Sarcoma
alpha - fetoprotein
malignant mesenchyme tumor (general)
Barrett's esophagus (chronic GI reflux)
bone benign tumor
45. Squamous cell carcinoma of skin
causes of increased ESR
immunodeficiency states
Neoplasm associated with actinic keratosis
Autoimmune (Hashimoto's - myasthenia gravis)
46. Melanoma 9p tumor suppressor
granulomatous disease
p16 gene
WT1 gene
ulcerative colitis
47. Colon cancer (Deleted in Colon Cancer) 18q tumor suppressor
granulomatous disease
blood vessels benign tumor
DCC gene
Red (hemorrhagic) infarcts
48. Cancer
paraneoplastic effects of leukemias and lymphomas
acanthosis nigricans (hyperpig and epidermal thickening)
Rb gene
Second - leading cause of death in the US
49. GIST cytokine receptor (oncogene)
Primary tumors that met to bone
secondary amyloidosis (reactive systemic)
breast cancer incidence/mortality
c - kit gene
50. Female 13%/23% and rising Male 16%/33% (mortality has plateaued)
lung cancer incidence/mortality
prostate cancer incidence/mortality
cigarette smoke target
Rb gene