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First Aid Basics

Subjects : health-sciences, first-aid

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Visceral malignancy (stomach - lung - breast - uterus)
bcl -2 gene
Leukocyte extravasation: rolling
primary amyloidosis
acanthosis nigricans (hyperpig and epidermal thickening)

2. Melanoma - basal cell carcinoma - and especially squamous cell carcinomas of the skin.
skeletal muscle malignant tumor
granulomatous disease
Neoplasm associated with xeroderma pigmentosum (albinism)
abl gene

3. Mature teratoma in women
Paget's bone disease
c - myc gene
benign >1 cell type tumor
CA-125

4. Liver (hepatocellular carcinoma)
aflatoxin target
immunodeficiency states
dysplastic nevus
N- myc gene

5. Rhabdomyosarcoma
benign epithelial tumor
skeletal muscle malignant tumor
primary amyloidosis
Pale infarcts

6. Erythropoietin
iron poisoning
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
Autoimmune (Hashimoto's - myasthenia gravis)
causes of decreased ESR

7. Tumor marker: neuroblastoma - lung and gastric cancer
Irreversible - plasias
Neoplasm associated with Down Syndrome
Bombesin
N- myc gene

8. GIST cytokine receptor (oncogene)
c - kit gene
Free radical eliminators
fat malignant tumor
Leukocyte extravasation: migration

9. Tumor marker: melanoma - neural tumors - astrocytomas
S-100
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)
lung cancer incidence/mortality
Irreversible - plasias

10. Hepatocellular carcinoma
iron poisoning
Colon and rectal cancer incidence
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants
cirrosis (alcohol - hepB or C)

11. AL
primary amyloidosis
Leading cause of death in the US
Alkylating agents target
Red (hemorrhagic) infarcts

12. Leiomyosarcoma
lung cancer incidence/mortality
alpha - fetoprotein
Primary tumors that met to liver
smooth muscle malignant tumor

13. Neutrophils (eos in the gut) - plus other granular leukocytes and antibodies.
DCC gene
Acute inflammatory mediators
vinyl chloride target
benign >1 cell type tumor

14. 32%/13% male
asbestos target
prostate cancer incidence/mortality
nitrosamines (smoked foods) target
primary amyloidosis

15. Tumor marker: carcinoembryonic Ag Very nonspecific
skeletal muscle malignant tumor
benign >1 cell type tumor
CEA
Where you see Psammoma bodies

16. Blood (leukemia)
Alkylating agents target
paraneoplastic effects of leukemias and lymphomas
Red (hemorrhagic) infarcts
skeletal muscle malignant tumor

17. Tumor marker: pancreatic adenocarcinoma
Neoplasm associated with xeroderma pigmentosum (albinism)
ulcerative colitis
CA-125
CA-19-9

18. Enzymatic degradation and protein denaturation due to exogenous injury. Inflammatory process where intracellular components extravasate.
radiation exposure
NF1 gene
Necrosis
Barrett's esophagus (chronic GI reflux)

19. Secondary osteosarcoma and fibrosarcoma

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20. Liver (centrilobular necrosis - fatty change)
extrinsic apoptosis
ulcerative colitis
paraneoplastic effects of leukemias and lymphomas
CCl4 target

21. Vascular: ICAM-1 Leukocyte: LFA-1 (integrin)
asbestos target
Reversible - plasias
Leukocyte extravasation: tight binding
beta - hCG

22. Most human cancers - specifically Li - Fraumeni syndrome 17p tumor suppressor (blocks G1 to S phase progression)
malignant >1 cell type tumor
p53 gene
Autoimmune (Hashimoto's - myasthenia gravis)
blood vessels benign tumor

23. Lung tumor transcription factor (oncogene)
Primary tumors that met to liver
Free radical cell damage
L- myc gene
Rb gene

24. Gastric adenocacinoma
Primary tumors that met to brain
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants
paraneoplastic effects of small cell lung carcinoma
paraneoplastic effects of renal cell carcinoma - hemangioblastoma

25. Restoration of normal structure - granulation tissue (vascularized + fibrosis) - abscess (fibrosis + pus) - fistula or scarring (collagen).
PSA
Resolution of inflammation
NF1 gene
causes of increased ESR

26. Sarcoma - papillary thyroid cancer
bcl -2 gene
radiation exposure
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)
DPC gene

27. Anaplasia - neoplasia - desmoplasia (fibrous tissue formation in response to neoplasm)
malignant >1 cell type tumor
immunodeficiency states
Irreversible - plasias
Primary tumors that met to liver

28. Colorectal cancer (assoc with FAP) 5q tumor suppressor
acanthosis nigricans (hyperpig and epidermal thickening)
Chronic inflammatory mediators
APC gene
blood cell malignant tumors

29. Hemangioma
cirrosis (alcohol - hepB or C)
L- myc gene
NF2 gene
blood vessels benign tumor

30. Tumor marker: tartrate - resistant acid phosphatase. Hairy cell leukemia (B- cell neoplasm)
Autoimmune (Hashimoto's - myasthenia gravis)
CA-125
TRAP
NF1 gene

31. Lung - breast - skin (melanoma) - kidney (renal cell carcinoma) - GI.50% brain tumors are from mets
blood cell malignant tumors
Paget's bone disease
Primary tumors that met to liver
Primary tumors that met to brain

32. Solid tissues with single blood supply. Heart - kidney and spleen.
Pale infarcts
Prostatic acid phosphatase
AIDS
p53 gene

33. Rhabdomyoma
skeletal muscle benign tumor
Second - leading cause of death in the US
Primary tumors that met to liver
iron poisoning

34. Tumor marker: Hydatifiform moles - choriocarcinomas - gestational trophoblastic tumors.
beta - hCG
Autoimmune (Hashimoto's - myasthenia gravis)
Primary tumors that met to brain
Pale infarcts

35. Caused by peroxidation of membrane lipids. Causes acute gastric bleeding and chronic metabolic acidosis and scarring.
smooth muscle benign tumor
DCC gene
iron poisoning
benign epithelial tumor

36. All - AML
Free radical cell damage
benign epithelial tumor
Neoplasm associated with Down Syndrome
c - myc gene

37. Bladder (transitional cell carcinoma)
Napthalene (aniline) dyes target
Free radical cell damage
extrinsic apoptosis
Red (hemorrhagic) infarcts

38. Squamous cell carcinoma of skin
smooth muscle malignant tumor
Alkylating agents target
Neoplasm associated with actinic keratosis
Leading cause of death in the US

39. Follicular and undifferentiated lymphomas anti - apoptotic molecule (oncogene)
ras gene
bcl -2 gene
Napthalene (aniline) dyes target
granulomatous disease

40. Pancreatic cancer (Deleted in Pancreatic Cancer) 18q tumor suppressor
beta - hCG
Primary tumors that met to bone
Leukocyte extravasation: tight binding
DPC gene

41. 32%/18% female
breast cancer incidence/mortality
extrinsic apoptosis
Barrett's esophagus (chronic GI reflux)
Colon and rectal cancer incidence

42. Burkitt's lymphoma transcription factor (oncogene)
causes of increased ESR
c - myc gene
blood cell malignant tumors
Alkylating agents target

43. Osteoma
Napthalene (aniline) dyes target
bone benign tumor
causes of increased ESR
calcitonin

44. Female 13%/23% and rising Male 16%/33% (mortality has plateaued)
blood vessels benign tumor
dysplastic nevus
Leukocyte extravasation: diapedesis
lung cancer incidence/mortality

45. Leiomyoma
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms
smooth muscle benign tumor
lung cancer incidence/mortality
erb - B2 gene

46. Esophagus - stomach
Pale infarcts
Prostatic acid phosphatase
nitrosamines (smoked foods) target
paraneoplastic effects of thymoma - small cell lung carcinoma

47. Colonic adenocarcinoma
causes of decreased ESR
ulcerative colitis
prostate cancer incidence/mortality
immunodeficiency states

48. Breast and ovarian cancer 17q tumor suppressor (DNA repair protein)
AIDS
BRCA1 gene
causes of increased ESR
Where you see Psammoma bodies

49. Squamous cell carcinoma of the esophagus
calcitonin
Primary tumors that met to liver
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)
Leading cause of death in the US

50. ADH
calcitonin
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms
Leukocyte extravasation: diapedesis
CA-125

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First Aid Basics

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