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First Aid Basics

Subjects : health-sciences, first-aid

Instructions:

Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can study here.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Hemangioma
Paget's bone disease
abl gene
blood vessels benign tumor
acanthosis nigricans (hyperpig and epidermal thickening)

2. Tumor marker: ovarian - malignant epithelial tumors.
malignant epithelial tumor
CA-125
paraneoplastic effects of small cell lung carcinoma
TRAP

3. Burkitt's lymphoma transcription factor (oncogene)
c - myc gene
iron poisoning
paraneoplastic effects of small cell lung carcinoma
L- myc gene

4. Neurofibromatosis type 2 22q tumor suppressor (key type 2=22)
erb - B2 gene
fat malignant tumor
NF2 gene
cigarette smoke target

5. Osteosarcoma
bone malignant tumor
Free radical cell damage
Necrosis
Napthalene (aniline) dyes target

6. Squamous cell carcinoma of skin
Leukocyte extravasation: diapedesis
secondary amyloidosis (reactive systemic)
primary amyloidosis
Neoplasm associated with actinic keratosis

7. Malignant melanoma
benign epithelial tumor
Resolution of inflammation
Napthalene (aniline) dyes target
dysplastic nevus

8. Colon>stomach>pancreas>breast>lung (liver and lung are the most common places for mets)
blood vessels benign tumor
causes of increased ESR
Primary tumors that met to brain
Primary tumors that met to liver

9. Breast cancer 13q tumor suppressor (DNA repair protein)
Free radical cell damage
BRAC2 gene
lung cancer incidence/mortality
blood vessels malignant tumor

10. Leukemia - lymphoma
blood cell malignant tumors
paraneoplastic effects of thymoma - small cell lung carcinoma
skeletal muscle malignant tumor
NF1 gene

11. Solid tissues with single blood supply. Heart - kidney and spleen.
benign >1 cell type tumor
radiation exposure
Pale infarcts
DCC gene

12. ADH
vinyl chloride target
granulomatous disease
AIDS
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms

13. Secondary osteosarcoma and fibrosarcoma

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14. During embryogenesis - hormone induction and atrophy. Increased mitochondrial permeability and cytochrome c release. Increase Bax (pro - apoptotic) - decreased Bcl -2 (anti - apopotic).
intrinsic apoptosis
bone benign tumor
blood cell malignant tumors
NF1 gene

15. Mature teratoma in men or malignant teratoma in M/F
Prostatic acid phosphatase
Autoimmune (Hashimoto's - myasthenia gravis)
malignant >1 cell type tumor
ret gene

16. Heart disease
Rb gene
Leading cause of death in the US
Reversible - plasias
WT1 gene

17. Hyperuricemia (excess NA turnover)
Free radical cell damage
paraneoplastic effects of leukemias and lymphomas
Pale infarcts
APC gene

18. Sickle cell (altered shape) - polycythemia (too many) - CHF (unknown)
blood vessels benign tumor
paraneoplastic effects of leukemias and lymphomas
causes of decreased ESR
Neoplasm associated with xeroderma pigmentosum (albinism)

19. Tumor marker: tartrate - resistant acid phosphatase. Hairy cell leukemia (B- cell neoplasm)
CEA
prostate cancer incidence/mortality
acanthosis nigricans (hyperpig and epidermal thickening)
TRAP

20. Tumor marker: carcinoembryonic Ag Very nonspecific
BRCA1 gene
Free radical eliminators
CEA
abl gene

21. Vascular: ICAM-1 Leukocyte: LFA-1 (integrin)
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms
Leukocyte extravasation: tight binding
Neoplasm associated with xeroderma pigmentosum (albinism)
smooth muscle benign tumor

22. AL
Primary tumors that met to bone
Neoplasm associated with actinic keratosis
ulcerative colitis
primary amyloidosis

23. ACTH or ACTH- like peptide
malignant mesenchyme tumor (general)
Free radical cell damage
paraneoplastic effects of small cell lung carcinoma
CA-125

24. Esophageal adenocarcinoma

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25. Female 13%/23% and rising Male 16%/33% (mortality has plateaued)
lung cancer incidence/mortality
APC gene
smooth muscle malignant tumor
Prostatic acid phosphatase

26. 32%/13% male
Rb gene
prostate cancer incidence/mortality
bone malignant tumor
p53 gene

27. Tumor marker: (Normal in fetus). Hepatocellular carcinomas. Nonseminomatous germ cell tumors of the testis.
NF2 gene
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)
alpha - fetoprotein
asbestos target

28. Lung (mesothelioma and bronchogenic carcinoma)
asbestos target
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)
Primary tumors that met to brain
Neoplasm associated with Down Syndrome

29. Gastric adenocacinoma
paraneoplastic effects of small cell lung carcinoma
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants
Second - leading cause of death in the US
skeletal muscle malignant tumor

30. PECAM-1
granulomatous disease
Prostatic acid phosphatase
cirrosis (alcohol - hepB or C)
Leukocyte extravasation: diapedesis

31. Erythropoietin
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
blood vessels malignant tumor
causes of increased ESR
Chronic inflammatory mediators

32. Lung tumor transcription factor (oncogene)
L- myc gene
Primary tumors that met to brain
Napthalene (aniline) dyes target
c - myc gene

33. Bladder (transitional cell carcinoma)
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
Free radical cell damage
Napthalene (aniline) dyes target
acanthosis nigricans (hyperpig and epidermal thickening)

34. Follicular and undifferentiated lymphomas anti - apoptotic molecule (oncogene)
cigarette smoke target
bcl -2 gene
Pale infarcts
granulomatous disease

35. Melanoma - basal cell carcinoma - and especially squamous cell carcinomas of the skin.
abl gene
Neoplasm associated with xeroderma pigmentosum (albinism)
benign >1 cell type tumor
iron poisoning

36. Mature teratoma in women
NF2 gene
Necrosis
benign >1 cell type tumor
skeletal muscle malignant tumor

37. Adenocarcinoma - papillary carcinoma
malignant epithelial tumor
dysplastic nevus
DPC gene
Barrett's esophagus (chronic GI reflux)

38. Caused by peroxidation of membrane lipids. Causes acute gastric bleeding and chronic metabolic acidosis and scarring.
Chronic inflammatory mediators
iron poisoning
blood cell malignant tumors
smooth muscle benign tumor

39. GIST cytokine receptor (oncogene)
ras gene
c - kit gene
Leading cause of death in the US
p16 gene

40. Lipoma
erb - B2 gene
Prostatic acid phosphatase
fat benign tumor
Red (hemorrhagic) infarcts

41. Breast - ovarian and gastric carcinomas tyrosine kinase (oncogene)
WT1 gene
paraneoplastic effects of leukemias and lymphomas
erb - B2 gene
Primary tumors that met to brain

42. Esophagus - stomach
p53 gene
nitrosamines (smoked foods) target
APC gene
Necrosis

43. Astrocytoma - angiomyolipoma - cardiac rhabdomyoma
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)
Free radical eliminators
skeletal muscle malignant tumor
TRAP

44. Sarcoma - papillary thyroid cancer
radiation exposure
beta - hCG
bcl -2 gene
Alkylating agents target

45. Enzymes: catalase - superoxide dismutase - glutathione peroxidase.Vitamins: ACE Spontaneous decay
Free radical eliminators
c - kit gene
blood vessels benign tumor
benign epithelial tumor

46. Membrane lipid peroxidation - protein modification and DNA breakage.
Leukocyte extravasation: tight binding
Free radical cell damage
causes of increased ESR
Free radical eliminators

47. 32%/18% female
Resolution of inflammation
breast cancer incidence/mortality
Reversible - plasias
prostate cancer incidence/mortality

48. Ligand - receptor interactions. Release of perforin and granzyme B.
causes of increased ESR
ret gene
extrinsic apoptosis
malignant >1 cell type tumor

49. Tumor marker: neuroblastoma - lung and gastric cancer
smooth muscle benign tumor
Bombesin
CEA
S-100

50. Prostate (blastic) - thyroid - testes - breast (lytic and blastic) - lung (lytic) - kidney (breast and prostate are most common)
Leukocyte extravasation: tight binding
ret gene
blood vessels benign tumor
Primary tumors that met to bone