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First Aid Basics

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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Osteoma

2. Aggressive malignant lymphomas (non - Hodgkin's) and Kaposi's sarcoma

3. Tumor marker: (Normal in fetus). Hepatocellular carcinomas. Nonseminomatous germ cell tumors of the testis.

4. Cancer

5. Malignant melanoma

6. Vascular: ICAM-1 Leukocyte: LFA-1 (integrin)

7. TB - fungal infections - syphilis - leprosy - cat scratch fever - sarcoid - Crohn's - Berylliosis.

8. Secondary osteosarcoma and fibrosarcoma

9. Breast - ovarian and gastric carcinomas tyrosine kinase (oncogene)

10. Lung - liver - intestine or following reperfusion.

11. Tumor marker: prostate carcinoma marker.

12. Breast cancer 13q tumor suppressor (DNA repair protein)

13. Hyperuricemia (excess NA turnover)

14. Caused by peroxidation of membrane lipids. Causes acute gastric bleeding and chronic metabolic acidosis and scarring.

15. Tumor marker: melanoma - neural tumors - astrocytomas

16. Tumor marker: tartrate - resistant acid phosphatase. Hairy cell leukemia (B- cell neoplasm)

17. Enzymatic degradation and protein denaturation due to exogenous injury. Inflammatory process where intracellular components extravasate.

18. Mature teratoma in men or malignant teratoma in M/F

19. Leiomyoma

20. Adenoma - papilloma

21. Membrane lipid peroxidation - protein modification and DNA breakage.

22. Melanoma - basal cell carcinoma - and especially squamous cell carcinomas of the skin.

23. Gastric adenocacinoma

24. AA

25. Malignant lymphoma

26. Infections - inflammation - cancer - pregnancy - SLE

27. Neuroblastoma transcription factor (oncogene)

28. Wilms' tumor 11p tumor suppressor

29. Pancreatic cancer (Deleted in Pancreatic Cancer) 18q tumor suppressor

30. Rhabdomyoma

31. Visceral malignancy (stomach - lung - breast - uterus)

32. Sarcoma - papillary thyroid cancer

33. Restoration of normal structure - granulation tissue (vascularized + fibrosis) - abscess (fibrosis + pus) - fistula or scarring (collagen).

34. Osteosarcoma

35. Liver (centrilobular necrosis - fatty change)

36. Macrophages and lymphocytes. Persistant destruction and repair.

37. Enzymes: catalase - superoxide dismutase - glutathione peroxidase.Vitamins: ACE Spontaneous decay

38. MEN type II and III tyrosine kinase (oncogene)

39. Liver (hepatocellular carcinoma)

40. Melanoma 9p tumor suppressor

41. Female 13%/23% and rising Male 16%/33% (mortality has plateaued)

42. CML tyrosine kinase (oncogene)

43. Squamous cell carcinoma of skin

44. During embryogenesis - hormone induction and atrophy. Increased mitochondrial permeability and cytochrome c release. Increase Bax (pro - apoptotic) - decreased Bcl -2 (anti - apopotic).

45. Squamous cell carcinoma of the esophagus

46. Astrocytoma - angiomyolipoma - cardiac rhabdomyoma

47. PECAM-1

48. Neutrophils (eos in the gut) - plus other granular leukocytes and antibodies.

49. Tumor marker: carcinoembryonic Ag Very nonspecific

50. Colorectal cancer (assoc with FAP) 5q tumor suppressor