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First Aid Basics

Subjects : health-sciences, first-aid

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Macrophages and lymphocytes. Persistant destruction and repair.
Necrosis
Chronic inflammatory mediators
p53 gene
c - kit gene

2. Pancreatic cancer (Deleted in Pancreatic Cancer) 18q tumor suppressor
DPC gene
causes of decreased ESR
Pale infarcts
NF1 gene

3. Breast - ovarian and gastric carcinomas tyrosine kinase (oncogene)
Primary tumors that met to brain
erb - B2 gene
skeletal muscle malignant tumor
Leukocyte extravasation: rolling

4. Lung (mesothelioma and bronchogenic carcinoma)
asbestos target
benign epithelial tumor
Bombesin
radiation exposure

5. Prostate (blastic) - thyroid - testes - breast (lytic and blastic) - lung (lytic) - kidney (breast and prostate are most common)
TRAP
Primary tumors that met to bone
Resolution of inflammation
Alk - phos

6. Astrocytoma - angiomyolipoma - cardiac rhabdomyoma
bone benign tumor
p53 gene
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.

7. Angiosarcoma
Necrosis
Prostatic acid phosphatase
NF1 gene
blood vessels malignant tumor

8. Aggressive malignant lymphomas (non - Hodgkin's) and Kaposi's sarcoma
smooth muscle benign tumor
cirrosis (alcohol - hepB or C)
AIDS
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.

9. Squamous cell carcinoma of the esophagus
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)
alpha - fetoprotein
CEA
Where you see Psammoma bodies

10. Neuroblastoma transcription factor (oncogene)
N- myc gene
Leukocyte extravasation: diapedesis
smooth muscle malignant tumor
Acute inflammatory mediators

11. Liver (hepatocellular carcinoma)
aflatoxin target
malignant epithelial tumor
c - kit gene
CA-125

12. Melanoma - basal cell carcinoma - and especially squamous cell carcinomas of the skin.
Neoplasm associated with xeroderma pigmentosum (albinism)
Where you see Psammoma bodies
Reversible - plasias
paraneoplastic effects of leukemias and lymphomas

13. Rhabdomyoma
Neoplasm associated with actinic keratosis
skeletal muscle benign tumor
erb - B2 gene
calcitonin

14. Follicular and undifferentiated lymphomas anti - apoptotic molecule (oncogene)
N- myc gene
bcl -2 gene
Pale infarcts
DCC gene

15. Esophageal adenocarcinoma

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16. GIST cytokine receptor (oncogene)
extrinsic apoptosis
breast cancer incidence/mortality
c - kit gene
Neoplasm associated with xeroderma pigmentosum (albinism)

17. Female 13% Male 12%
Neoplasm associated with xeroderma pigmentosum (albinism)
Neoplasm associated with actinic keratosis
Colon and rectal cancer incidence
Pale infarcts

18. Vascular: ICAM-1 Leukocyte: LFA-1 (integrin)
Irreversible - plasias
Rb gene
Leukocyte extravasation: migration
Leukocyte extravasation: tight binding

19. Bladder (transitional cell carcinoma)
Neoplasm associated with Down Syndrome
Napthalene (aniline) dyes target
granulomatous disease
BRCA1 gene

20. Liver (centrilobular necrosis - fatty change)
skeletal muscle benign tumor
p53 gene
CCl4 target
Chronic inflammatory mediators

21. Leiomyosarcoma
BRCA1 gene
smooth muscle malignant tumor
WT1 gene
Colon and rectal cancer incidence

22. Hyperplasia - metaplasia - dysplasia
skeletal muscle benign tumor
Alkylating agents target
blood vessels malignant tumor
Reversible - plasias

23. Ligand - receptor interactions. Release of perforin and granzyme B.
lung cancer incidence/mortality
Prostatic acid phosphatase
smooth muscle malignant tumor
extrinsic apoptosis

24. Erythropoietin
ret gene
p16 gene
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
Irreversible - plasias

25. Blood (leukemia)
DPC gene
immunodeficiency states
Resolution of inflammation
Alkylating agents target

26. Bacterial products (CLIK):C5a - LTB4 - IL-8 - Kallikrein
Free radical cell damage
Leukocyte extravasation: migration
immunodeficiency states
lung cancer incidence/mortality

27. Mature teratoma in men or malignant teratoma in M/F
erb - B2 gene
BRAC2 gene
NF1 gene
malignant >1 cell type tumor

28. Cancer
bone benign tumor
aflatoxin target
extrinsic apoptosis
Second - leading cause of death in the US

29. Leiomyoma
Colon and rectal cancer incidence
fat malignant tumor
smooth muscle benign tumor
iron poisoning

30. MEN type II and III tyrosine kinase (oncogene)
iron poisoning
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)
radiation exposure
ret gene

31. Tumor marker: carcinoembryonic Ag Very nonspecific
CEA
aflatoxin target
dysplastic nevus
Free radical eliminators

32. Caused by peroxidation of membrane lipids. Causes acute gastric bleeding and chronic metabolic acidosis and scarring.
benign >1 cell type tumor
breast cancer incidence/mortality
iron poisoning
causes of decreased ESR

33. Osteoma
Resolution of inflammation
bone benign tumor
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.
BRAC2 gene

34. Leukemia - lymphoma
Neoplasm associated with actinic keratosis
malignant epithelial tumor
Acute inflammatory mediators
blood cell malignant tumors

35. Restoration of normal structure - granulation tissue (vascularized + fibrosis) - abscess (fibrosis + pus) - fistula or scarring (collagen).
Leukocyte extravasation: migration
Chronic inflammatory mediators
Primary tumors that met to brain
Resolution of inflammation

36. Tumor marker: (Normal in fetus). Hepatocellular carcinomas. Nonseminomatous germ cell tumors of the testis.
alpha - fetoprotein
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)
immunodeficiency states
bcl -2 gene

37. Colon>stomach>pancreas>breast>lung (liver and lung are the most common places for mets)
Autoimmune (Hashimoto's - myasthenia gravis)
benign >1 cell type tumor
Primary tumors that met to liver
TRAP

38. Tumor marker: prostate carcinoma marker.
NF2 gene
ras gene
Prostatic acid phosphatase
radiation exposure

39. Lung tumor transcription factor (oncogene)
beta - hCG
extrinsic apoptosis
blood vessels malignant tumor
L- myc gene

40. During embryogenesis - hormone induction and atrophy. Increased mitochondrial permeability and cytochrome c release. Increase Bax (pro - apoptotic) - decreased Bcl -2 (anti - apopotic).
intrinsic apoptosis
CA-19-9
Barrett's esophagus (chronic GI reflux)
Free radical cell damage

41. Female 13%/23% and rising Male 16%/33% (mortality has plateaued)
breast cancer incidence/mortality
lung cancer incidence/mortality
erb - B2 gene
smooth muscle benign tumor

42. Esophagus - stomach
nitrosamines (smoked foods) target
Pale infarcts
prostate cancer incidence/mortality
CEA

43. Hyperuricemia (excess NA turnover)
iron poisoning
Bombesin
paraneoplastic effects of leukemias and lymphomas
ulcerative colitis

44. Tumor marker: melanoma - neural tumors - astrocytomas
Pale infarcts
S-100
cigarette smoke target
c - kit gene

45. Breast cancer 13q tumor suppressor (DNA repair protein)
arsenic target
BRAC2 gene
benign >1 cell type tumor
paraneoplastic effects of renal cell carcinoma - hemangioblastoma

46. Antibodies to presynaptic Ca2+ channels at NM junction
Neoplasm associated with xeroderma pigmentosum (albinism)
CA-125
paraneoplastic effects of thymoma - small cell lung carcinoma
Barrett's esophagus (chronic GI reflux)

47. Vascular: E and P- selectin Leukocyte: Sialyl Lewis
CA-125
secondary amyloidosis (reactive systemic)
Leukocyte extravasation: rolling
alpha - fetoprotein

48. Mature teratoma in women
Resolution of inflammation
AIDS
benign >1 cell type tumor
paraneoplastic effects of small cell lung carcinoma

49. AA
secondary amyloidosis (reactive systemic)
p16 gene
nitrosamines (smoked foods) target
calcitonin

50. Sarcoma - papillary thyroid cancer
Rb gene
radiation exposure
arsenic target
Primary tumors that met to bone

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First Aid Basics

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