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Test your basic knowledge |
First Aid Basics
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Pancreatic cancer (Deleted in Pancreatic Cancer) 18q tumor suppressor
Primary tumors that met to brain
DCC gene
DPC gene
nitrosamines (smoked foods) target
2. Gastric adenocacinoma
asbestos target
prostate cancer incidence/mortality
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants
3. Squamous cell carcinoma of the esophagus
PSA
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)
Primary tumors that met to liver
Leukocyte extravasation: diapedesis
4. Most human cancers - specifically Li - Fraumeni syndrome 17p tumor suppressor (blocks G1 to S phase progression)
CA-125
TRAP
p53 gene
ret gene
5. Astrocytoma - angiomyolipoma - cardiac rhabdomyoma
BRCA1 gene
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)
causes of increased ESR
Primary tumors that met to brain
6. Esophagus - stomach
N- myc gene
NF2 gene
nitrosamines (smoked foods) target
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
7. Hepatocellular carcinoma
Primary tumors that met to bone
Where you see Psammoma bodies
bcl -2 gene
cirrosis (alcohol - hepB or C)
8. Bacterial products (CLIK):C5a - LTB4 - IL-8 - Kallikrein
calcitonin
Leukocyte extravasation: migration
lung cancer incidence/mortality
smooth muscle malignant tumor
9. Restoration of normal structure - granulation tissue (vascularized + fibrosis) - abscess (fibrosis + pus) - fistula or scarring (collagen).
granulomatous disease
cigarette smoke target
Resolution of inflammation
CA-125
10. Wilms' tumor 11p tumor suppressor
acanthosis nigricans (hyperpig and epidermal thickening)
Colon and rectal cancer incidence
WT1 gene
blood cell malignant tumors
11. Mature teratoma in men or malignant teratoma in M/F
malignant >1 cell type tumor
primary amyloidosis
prostate cancer incidence/mortality
Where you see Psammoma bodies
12. Female 13%/23% and rising Male 16%/33% (mortality has plateaued)
lung cancer incidence/mortality
causes of increased ESR
acanthosis nigricans (hyperpig and epidermal thickening)
prostate cancer incidence/mortality
13. Colon>stomach>pancreas>breast>lung (liver and lung are the most common places for mets)
Primary tumors that met to brain
p16 gene
Primary tumors that met to liver
smooth muscle malignant tumor
14. Hyperuricemia (excess NA turnover)
asbestos target
paraneoplastic effects of leukemias and lymphomas
Bombesin
Free radical cell damage
15. Larynx (SqCC) - lung (SqCC and SCC) - kidney (renal cell carcinoma) - bladder (transitional cell carcinoma)
malignant >1 cell type tumor
cigarette smoke target
Necrosis
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
16. PTH- related peptide - TGF- beta - TNF - IL-1
paraneoplastic effects of thymoma - small cell lung carcinoma
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.
prostate cancer incidence/mortality
17. Colorectal cancer (assoc with FAP) 5q tumor suppressor
APC gene
Alkylating agents target
bcl -2 gene
cirrosis (alcohol - hepB or C)
18. Tumor marker: (Normal in fetus). Hepatocellular carcinomas. Nonseminomatous germ cell tumors of the testis.
Primary tumors that met to brain
skeletal muscle malignant tumor
acanthosis nigricans (hyperpig and epidermal thickening)
alpha - fetoprotein
19. Rhabdomyoma
Primary tumors that met to liver
skeletal muscle benign tumor
fat malignant tumor
benign epithelial tumor
20. Tumor marker: pancreatic adenocarcinoma
CA-19-9
benign >1 cell type tumor
bone malignant tumor
breast cancer incidence/mortality
21. Tumor marker: tartrate - resistant acid phosphatase. Hairy cell leukemia (B- cell neoplasm)
ras gene
blood vessels benign tumor
TRAP
Paget's bone disease
22. Breast - ovarian and gastric carcinomas tyrosine kinase (oncogene)
granulomatous disease
erb - B2 gene
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants
fat benign tumor
23. ACTH or ACTH- like peptide
paraneoplastic effects of small cell lung carcinoma
CEA
CA-125
skeletal muscle malignant tumor
24. Malignant lymphoma
p53 gene
CA-125
immunodeficiency states
smooth muscle malignant tumor
25. Liposarcoma
fat malignant tumor
Pale infarcts
bcl -2 gene
smooth muscle benign tumor
26. Sarcoma
arsenic target
malignant mesenchyme tumor (general)
CA-19-9
acanthosis nigricans (hyperpig and epidermal thickening)
27. Colonic adenocarcinoma
bone benign tumor
ulcerative colitis
cigarette smoke target
vinyl chloride target
28. Neurofibromatosis type 1 17q tumor suppressor
NF1 gene
benign >1 cell type tumor
secondary amyloidosis (reactive systemic)
bcl -2 gene
29. GIST cytokine receptor (oncogene)
Napthalene (aniline) dyes target
c - kit gene
immunodeficiency states
Necrosis
30. Visceral malignancy (stomach - lung - breast - uterus)
acanthosis nigricans (hyperpig and epidermal thickening)
CEA
Barrett's esophagus (chronic GI reflux)
abl gene
31. Lung tumor transcription factor (oncogene)
radiation exposure
L- myc gene
NF1 gene
bone malignant tumor
32. Caused by peroxidation of membrane lipids. Causes acute gastric bleeding and chronic metabolic acidosis and scarring.
nitrosamines (smoked foods) target
Necrosis
skeletal muscle benign tumor
iron poisoning
33. Hemangioma
aflatoxin target
c - kit gene
secondary amyloidosis (reactive systemic)
blood vessels benign tumor
34. Ligand - receptor interactions. Release of perforin and granzyme B.
fat benign tumor
smooth muscle malignant tumor
extrinsic apoptosis
bcl -2 gene
35. Neuroblastoma transcription factor (oncogene)
benign epithelial tumor
paraneoplastic effects of thymoma - small cell lung carcinoma
Pale infarcts
N- myc gene
36. Tumor marker: neuroblastoma - lung and gastric cancer
CA-19-9
Bombesin
malignant >1 cell type tumor
Autoimmune (Hashimoto's - myasthenia gravis)
37. Lymphoma
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38. Angiosarcoma
bcl -2 gene
fat malignant tumor
Prostatic acid phosphatase
blood vessels malignant tumor
39. Tumor marker: Screen for prostate carcinoma. Can also be elevated in BPH and prostatitis.
PSA
paraneoplastic effects of small cell lung carcinoma
Paget's bone disease
p53 gene
40. Secondary osteosarcoma and fibrosarcoma
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41. Squamous cell carcinoma of skin
c - myc gene
fat malignant tumor
Neoplasm associated with actinic keratosis
aflatoxin target
42. Tumor marker: carcinoembryonic Ag Very nonspecific
Red (hemorrhagic) infarcts
CEA
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)
Free radical eliminators
43. Malignant melanoma
p16 gene
dysplastic nevus
N- myc gene
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.
44. Follicular and undifferentiated lymphomas anti - apoptotic molecule (oncogene)
bcl -2 gene
Necrosis
vinyl chloride target
Prostatic acid phosphatase
45. Breast and ovarian cancer 17q tumor suppressor (DNA repair protein)
Acute inflammatory mediators
L- myc gene
BRCA1 gene
CCl4 target
46. TB - fungal infections - syphilis - leprosy - cat scratch fever - sarcoid - Crohn's - Berylliosis.
primary amyloidosis
granulomatous disease
immunodeficiency states
N- myc gene
47. Retinoblastoma - osteosarcoma 13q tumor suppressor (blocks G1 to S phase progression)
Rb gene
BRAC2 gene
DPC gene
Leukocyte extravasation: migration
48. Blood (leukemia)
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)
secondary amyloidosis (reactive systemic)
Alkylating agents target
Barrett's esophagus (chronic GI reflux)
49. Adenocarcinoma - papillary carcinoma
aflatoxin target
blood vessels benign tumor
malignant epithelial tumor
alpha - fetoprotein
50. Lipoma
Red (hemorrhagic) infarcts
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms
blood cell malignant tumors
fat benign tumor