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First Aid Basics

Subjects : health-sciences, first-aid

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Esophagus - stomach
asbestos target
Free radical cell damage
p53 gene
nitrosamines (smoked foods) target

2. Neurofibromatosis type 2 22q tumor suppressor (key type 2=22)
vinyl chloride target
NF2 gene
blood vessels benign tumor
BRAC2 gene

3. Tumor marker: prostate carcinoma marker.
malignant >1 cell type tumor
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants
L- myc gene
Prostatic acid phosphatase

4. CML tyrosine kinase (oncogene)
extrinsic apoptosis
abl gene
Leading cause of death in the US
CA-125

5. Angiosarcoma
blood vessels malignant tumor
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms
lung cancer incidence/mortality
Leukocyte extravasation: tight binding

6. Colon>stomach>pancreas>breast>lung (liver and lung are the most common places for mets)
WT1 gene
Primary tumors that met to liver
c - myc gene
smooth muscle benign tumor

7. Tumor marker: thyroid medullary carcinoma
smooth muscle benign tumor
calcitonin
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms
BRCA1 gene

8. Erythropoietin
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
bcl -2 gene
erb - B2 gene
blood cell malignant tumors

9. Mature teratoma in men or malignant teratoma in M/F
malignant >1 cell type tumor
Paget's bone disease
Bombesin
WT1 gene

10. Mature teratoma in women
CA-19-9
Necrosis
BRAC2 gene
benign >1 cell type tumor

11. During embryogenesis - hormone induction and atrophy. Increased mitochondrial permeability and cytochrome c release. Increase Bax (pro - apoptotic) - decreased Bcl -2 (anti - apopotic).
Red (hemorrhagic) infarcts
arsenic target
intrinsic apoptosis
Free radical eliminators

12. Bacterial products (CLIK):C5a - LTB4 - IL-8 - Kallikrein
AIDS
Where you see Psammoma bodies
Leukocyte extravasation: migration
Reversible - plasias

13. Lung - liver - intestine or following reperfusion.
erb - B2 gene
Red (hemorrhagic) infarcts
bcl -2 gene
Alk - phos

14. Enzymatic degradation and protein denaturation due to exogenous injury. Inflammatory process where intracellular components extravasate.
S-100
Necrosis
arsenic target
Neoplasm associated with Down Syndrome

15. Tumor marker: Hydatifiform moles - choriocarcinomas - gestational trophoblastic tumors.
immunodeficiency states
bone benign tumor
CCl4 target
beta - hCG

16. Neuroblastoma transcription factor (oncogene)
N- myc gene
bone benign tumor
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)
prostate cancer incidence/mortality

17. Tumor marker: mets to bone - obstructive biliary disease - Paget's
Rb gene
Leukocyte extravasation: migration
calcitonin
Alk - phos

18. ADH
p53 gene
Leukocyte extravasation: tight binding
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms
p16 gene

19. Breast cancer 13q tumor suppressor (DNA repair protein)
Leukocyte extravasation: migration
asbestos target
BRAC2 gene
abl gene

20. Liver (angiosarcoma)
NF2 gene
vinyl chloride target
paraneoplastic effects of small cell lung carcinoma
BRAC2 gene

21. Malignant lymphoma
intrinsic apoptosis
radiation exposure
immunodeficiency states
bcl -2 gene

22. Melanoma 9p tumor suppressor
Alk - phos
p16 gene
ret gene
paraneoplastic effects of small cell lung carcinoma

23. Osteosarcoma
extrinsic apoptosis
bone malignant tumor
S-100
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants

24. Caused by peroxidation of membrane lipids. Causes acute gastric bleeding and chronic metabolic acidosis and scarring.
p53 gene
CCl4 target
iron poisoning
Bombesin

25. Adenoma - papilloma
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants
benign epithelial tumor
Primary tumors that met to liver
smooth muscle benign tumor

26. All - AML
Where you see Psammoma bodies
Neoplasm associated with Down Syndrome
bone benign tumor
ras gene

27. Solid tissues with single blood supply. Heart - kidney and spleen.
ret gene
calcitonin
erb - B2 gene
Pale infarcts

28. Rhabdomyoma
ulcerative colitis
breast cancer incidence/mortality
skeletal muscle benign tumor
Barrett's esophagus (chronic GI reflux)

29. Tumor marker: ovarian - malignant epithelial tumors.
iron poisoning
CA-125
bone benign tumor
fat malignant tumor

30. Lymphoma

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31. Squamous cell carcinoma of the esophagus
acanthosis nigricans (hyperpig and epidermal thickening)
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)
ret gene
paraneoplastic effects of small cell lung carcinoma

32. Hemangioma
Prostatic acid phosphatase
asbestos target
blood vessels benign tumor
vinyl chloride target

33. ACTH or ACTH- like peptide
radiation exposure
paraneoplastic effects of small cell lung carcinoma
Colon and rectal cancer incidence
CA-19-9

34. Sarcoma - papillary thyroid cancer
radiation exposure
extrinsic apoptosis
primary amyloidosis
Leukocyte extravasation: migration

35. GIST cytokine receptor (oncogene)
benign epithelial tumor
c - kit gene
NF2 gene
Second - leading cause of death in the US

36. Hepatocellular carcinoma
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)
Leading cause of death in the US
ulcerative colitis
cirrosis (alcohol - hepB or C)

37. Leiomyosarcoma
c - myc gene
Chronic inflammatory mediators
smooth muscle malignant tumor
acanthosis nigricans (hyperpig and epidermal thickening)

38. Vascular: ICAM-1 Leukocyte: LFA-1 (integrin)
TRAP
breast cancer incidence/mortality
Leukocyte extravasation: tight binding
Reversible - plasias

39. Tumor marker: tartrate - resistant acid phosphatase. Hairy cell leukemia (B- cell neoplasm)
benign epithelial tumor
TRAP
ras gene
paraneoplastic effects of renal cell carcinoma - hemangioblastoma

40. TB - fungal infections - syphilis - leprosy - cat scratch fever - sarcoid - Crohn's - Berylliosis.
skeletal muscle benign tumor
Primary tumors that met to bone
Colon and rectal cancer incidence
granulomatous disease

41. Pancreatic cancer (Deleted in Pancreatic Cancer) 18q tumor suppressor
bone benign tumor
CA-19-9
DPC gene
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)

42. Liver (hepatocellular carcinoma)
smooth muscle malignant tumor
Primary tumors that met to bone
aflatoxin target
benign epithelial tumor

43. Esophageal adenocarcinoma

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44. Follicular and undifferentiated lymphomas anti - apoptotic molecule (oncogene)
bcl -2 gene
PSA
Pale infarcts
Free radical eliminators

45. 32%/13% male
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)
lung cancer incidence/mortality
prostate cancer incidence/mortality
skeletal muscle malignant tumor

46. Rhabdomyosarcoma
Second - leading cause of death in the US
granulomatous disease
skeletal muscle malignant tumor
p16 gene

47. Papillary (thyroid) - Serous (ovary) - Meningioma - Mesothelioma
N- myc gene
causes of decreased ESR
cirrosis (alcohol - hepB or C)
Where you see Psammoma bodies

48. Skin (SqCC) - liver (angiosarcoma)
blood vessels malignant tumor
arsenic target
malignant >1 cell type tumor
Leukocyte extravasation: rolling

49. Tumor marker: neuroblastoma - lung and gastric cancer
Colon and rectal cancer incidence
skeletal muscle benign tumor
Bombesin
BRCA1 gene

50. Colon cancer (Deleted in Colon Cancer) 18q tumor suppressor
Primary tumors that met to liver
Alkylating agents target
DCC gene
Rb gene

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First Aid Basics

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