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First Aid Basics

Subjects : health-sciences, first-aid

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Leiomyoma
APC gene
N- myc gene
smooth muscle benign tumor
CCl4 target

2. Neutrophils (eos in the gut) - plus other granular leukocytes and antibodies.
causes of decreased ESR
abl gene
Acute inflammatory mediators
Primary tumors that met to liver

3. MEN type II and III tyrosine kinase (oncogene)
benign epithelial tumor
ret gene
Neoplasm associated with Down Syndrome
bone malignant tumor

4. Follicular and undifferentiated lymphomas anti - apoptotic molecule (oncogene)
WT1 gene
bcl -2 gene
Where you see Psammoma bodies
NF1 gene

5. During embryogenesis - hormone induction and atrophy. Increased mitochondrial permeability and cytochrome c release. Increase Bax (pro - apoptotic) - decreased Bcl -2 (anti - apopotic).
Primary tumors that met to bone
fat benign tumor
Leukocyte extravasation: rolling
intrinsic apoptosis

6. Anaplasia - neoplasia - desmoplasia (fibrous tissue formation in response to neoplasm)
smooth muscle malignant tumor
Irreversible - plasias
CCl4 target
Prostatic acid phosphatase

7. Tumor marker: thyroid medullary carcinoma
malignant >1 cell type tumor
calcitonin
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)
c - myc gene

8. All - AML
granulomatous disease
CEA
Neoplasm associated with Down Syndrome
Autoimmune (Hashimoto's - myasthenia gravis)

9. Lipoma
Irreversible - plasias
Free radical cell damage
fat benign tumor
NF2 gene

10. Tumor marker: ovarian - malignant epithelial tumors.
cigarette smoke target
APC gene
Pale infarcts
CA-125

11. Sarcoma - papillary thyroid cancer
Leukocyte extravasation: rolling
Primary tumors that met to brain
Neoplasm associated with Down Syndrome
radiation exposure

12. Neurofibromatosis type 1 17q tumor suppressor
Leukocyte extravasation: rolling
NF1 gene
iron poisoning
CA-125

13. Rhabdomyosarcoma
Red (hemorrhagic) infarcts
vinyl chloride target
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
skeletal muscle malignant tumor

14. Female 13% Male 12%
Colon and rectal cancer incidence
paraneoplastic effects of thymoma - small cell lung carcinoma
Primary tumors that met to brain
skeletal muscle benign tumor

15. Melanoma - basal cell carcinoma - and especially squamous cell carcinomas of the skin.
primary amyloidosis
Neoplasm associated with xeroderma pigmentosum (albinism)
c - kit gene
malignant epithelial tumor

16. Rhabdomyoma
radiation exposure
benign >1 cell type tumor
Second - leading cause of death in the US
skeletal muscle benign tumor

17. Tumor marker: mets to bone - obstructive biliary disease - Paget's
nitrosamines (smoked foods) target
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms
bone benign tumor
Alk - phos

18. Heart disease
Leading cause of death in the US
DCC gene
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms
breast cancer incidence/mortality

19. Macrophages and lymphocytes. Persistant destruction and repair.
blood vessels benign tumor
Chronic inflammatory mediators
malignant >1 cell type tumor
Autoimmune (Hashimoto's - myasthenia gravis)

20. Osteoma
N- myc gene
bone benign tumor
Where you see Psammoma bodies
NF1 gene

21. Adenoma - papilloma
vinyl chloride target
Bombesin
extrinsic apoptosis
benign epithelial tumor

22. Leukemia - lymphoma
blood cell malignant tumors
malignant >1 cell type tumor
APC gene
Free radical cell damage

23. Colon carcinoma GTPase (oncogene)
ras gene
radiation exposure
nitrosamines (smoked foods) target
Irreversible - plasias

24. Bacterial products (CLIK):C5a - LTB4 - IL-8 - Kallikrein
NF1 gene
cigarette smoke target
TRAP
Leukocyte extravasation: migration

25. Leiomyosarcoma
Neoplasm associated with xeroderma pigmentosum (albinism)
smooth muscle malignant tumor
paraneoplastic effects of leukemias and lymphomas
Alk - phos

26. Blood (leukemia)
Alkylating agents target
Barrett's esophagus (chronic GI reflux)
lung cancer incidence/mortality
abl gene

27. Angiosarcoma
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms
Reversible - plasias
Napthalene (aniline) dyes target
blood vessels malignant tumor

28. Lymphoma

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29. Esophagus - stomach
nitrosamines (smoked foods) target
Autoimmune (Hashimoto's - myasthenia gravis)
TRAP
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms

30. PECAM-1
fat malignant tumor
Leukocyte extravasation: diapedesis
PSA
blood vessels benign tumor

31. Membrane lipid peroxidation - protein modification and DNA breakage.
extrinsic apoptosis
DPC gene
Free radical cell damage
intrinsic apoptosis

32. ACTH or ACTH- like peptide
c - kit gene
immunodeficiency states
paraneoplastic effects of small cell lung carcinoma
Colon and rectal cancer incidence

33. Female 13%/23% and rising Male 16%/33% (mortality has plateaued)
Primary tumors that met to liver
lung cancer incidence/mortality
benign epithelial tumor
secondary amyloidosis (reactive systemic)

34. Ligand - receptor interactions. Release of perforin and granzyme B.
malignant epithelial tumor
AIDS
cirrosis (alcohol - hepB or C)
extrinsic apoptosis

35. Esophageal adenocarcinoma

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36. Antibodies to presynaptic Ca2+ channels at NM junction
c - kit gene
smooth muscle benign tumor
paraneoplastic effects of thymoma - small cell lung carcinoma
skeletal muscle malignant tumor

37. Solid tissues with single blood supply. Heart - kidney and spleen.
Necrosis
arsenic target
Pale infarcts
malignant epithelial tumor

38. Skin (SqCC) - liver (angiosarcoma)
calcitonin
c - myc gene
arsenic target
primary amyloidosis

39. Enzymatic degradation and protein denaturation due to exogenous injury. Inflammatory process where intracellular components extravasate.
radiation exposure
Necrosis
abl gene
ulcerative colitis

40. Tumor marker: (Normal in fetus). Hepatocellular carcinomas. Nonseminomatous germ cell tumors of the testis.
NF1 gene
alpha - fetoprotein
Bombesin
benign >1 cell type tumor

41. Vascular: ICAM-1 Leukocyte: LFA-1 (integrin)
causes of increased ESR
Leukocyte extravasation: tight binding
causes of decreased ESR
APC gene

42. Colon cancer (Deleted in Colon Cancer) 18q tumor suppressor
Acute inflammatory mediators
DCC gene
Leukocyte extravasation: migration
Leukocyte extravasation: rolling

43. Mature teratoma in men or malignant teratoma in M/F
APC gene
malignant >1 cell type tumor
Leukocyte extravasation: migration
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)

44. Tumor marker: neuroblastoma - lung and gastric cancer
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants
N- myc gene
p53 gene
Bombesin

45. Liver (angiosarcoma)
Reversible - plasias
vinyl chloride target
asbestos target
Resolution of inflammation

46. Tumor marker: Screen for prostate carcinoma. Can also be elevated in BPH and prostatitis.
malignant >1 cell type tumor
Leukocyte extravasation: tight binding
DCC gene
PSA

47. Tumor marker: carcinoembryonic Ag Very nonspecific
Primary tumors that met to liver
Alkylating agents target
CEA
c - myc gene

48. Prostate (blastic) - thyroid - testes - breast (lytic and blastic) - lung (lytic) - kidney (breast and prostate are most common)
Primary tumors that met to bone
CCl4 target
Prostatic acid phosphatase
Leukocyte extravasation: diapedesis

49. Astrocytoma - angiomyolipoma - cardiac rhabdomyoma
granulomatous disease
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)
CCl4 target
paraneoplastic effects of small cell lung carcinoma

50. Breast - ovarian and gastric carcinomas tyrosine kinase (oncogene)
primary amyloidosis
erb - B2 gene
CEA
Primary tumors that met to liver

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First Aid Basics

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