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Test your basic knowledge |
First Aid Basics
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Bladder (transitional cell carcinoma)
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)
causes of increased ESR
Napthalene (aniline) dyes target
Neoplasm associated with Down Syndrome
2. Secondary osteosarcoma and fibrosarcoma
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3. Wilms' tumor 11p tumor suppressor
S-100
WT1 gene
causes of increased ESR
erb - B2 gene
4. Enzymatic degradation and protein denaturation due to exogenous injury. Inflammatory process where intracellular components extravasate.
bone malignant tumor
secondary amyloidosis (reactive systemic)
Necrosis
Second - leading cause of death in the US
5. Hepatocellular carcinoma
S-100
cirrosis (alcohol - hepB or C)
causes of decreased ESR
abl gene
6. Breast - ovarian and gastric carcinomas tyrosine kinase (oncogene)
Leading cause of death in the US
erb - B2 gene
N- myc gene
smooth muscle benign tumor
7. Squamous cell carcinoma of the esophagus
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)
BRAC2 gene
asbestos target
skeletal muscle benign tumor
8. MEN type II and III tyrosine kinase (oncogene)
Alkylating agents target
Second - leading cause of death in the US
causes of increased ESR
ret gene
9. All - AML
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms
alpha - fetoprotein
nitrosamines (smoked foods) target
Neoplasm associated with Down Syndrome
10. Leukemia - lymphoma
ras gene
fat malignant tumor
Paget's bone disease
blood cell malignant tumors
11. Esophagus - stomach
primary amyloidosis
Rb gene
TRAP
nitrosamines (smoked foods) target
12. Erythropoietin
iron poisoning
NF2 gene
nitrosamines (smoked foods) target
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
13. PTH- related peptide - TGF- beta - TNF - IL-1
NF1 gene
Primary tumors that met to brain
Leukocyte extravasation: tight binding
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.
14. Papillary (thyroid) - Serous (ovary) - Meningioma - Mesothelioma
Where you see Psammoma bodies
Resolution of inflammation
Leukocyte extravasation: diapedesis
Pale infarcts
15. Hemangioma
Leukocyte extravasation: rolling
blood vessels malignant tumor
prostate cancer incidence/mortality
blood vessels benign tumor
16. Aggressive malignant lymphomas (non - Hodgkin's) and Kaposi's sarcoma
vinyl chloride target
primary amyloidosis
Primary tumors that met to liver
AIDS
17. Most human cancers - specifically Li - Fraumeni syndrome 17p tumor suppressor (blocks G1 to S phase progression)
breast cancer incidence/mortality
NF1 gene
p53 gene
Primary tumors that met to bone
18. Membrane lipid peroxidation - protein modification and DNA breakage.
Pale infarcts
Alk - phos
Free radical cell damage
primary amyloidosis
19. 32%/13% male
malignant mesenchyme tumor (general)
radiation exposure
prostate cancer incidence/mortality
primary amyloidosis
20. Melanoma - basal cell carcinoma - and especially squamous cell carcinomas of the skin.
cigarette smoke target
Neoplasm associated with xeroderma pigmentosum (albinism)
Rb gene
blood cell malignant tumors
21. Prostate (blastic) - thyroid - testes - breast (lytic and blastic) - lung (lytic) - kidney (breast and prostate are most common)
blood vessels malignant tumor
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)
Primary tumors that met to bone
Paget's bone disease
22. Antibodies to presynaptic Ca2+ channels at NM junction
CCl4 target
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
paraneoplastic effects of thymoma - small cell lung carcinoma
Irreversible - plasias
23. Colorectal cancer (assoc with FAP) 5q tumor suppressor
BRCA1 gene
malignant >1 cell type tumor
APC gene
Neoplasm associated with actinic keratosis
24. AL
smooth muscle benign tumor
blood vessels benign tumor
primary amyloidosis
CA-125
25. Sarcoma - papillary thyroid cancer
Reversible - plasias
radiation exposure
Primary tumors that met to liver
skeletal muscle benign tumor
26. Colon cancer (Deleted in Colon Cancer) 18q tumor suppressor
calcitonin
arsenic target
Where you see Psammoma bodies
DCC gene
27. Blood (leukemia)
Alkylating agents target
BRCA1 gene
CA-19-9
calcitonin
28. Burkitt's lymphoma transcription factor (oncogene)
prostate cancer incidence/mortality
c - myc gene
intrinsic apoptosis
PSA
29. Lung tumor transcription factor (oncogene)
dysplastic nevus
calcitonin
Second - leading cause of death in the US
L- myc gene
30. Tumor marker: (Normal in fetus). Hepatocellular carcinomas. Nonseminomatous germ cell tumors of the testis.
alpha - fetoprotein
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants
extrinsic apoptosis
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms
31. Leiomyosarcoma
Paget's bone disease
BRCA1 gene
Chronic inflammatory mediators
smooth muscle malignant tumor
32. Anaplasia - neoplasia - desmoplasia (fibrous tissue formation in response to neoplasm)
Irreversible - plasias
CA-125
Prostatic acid phosphatase
BRAC2 gene
33. Infections - inflammation - cancer - pregnancy - SLE
p53 gene
Neoplasm associated with xeroderma pigmentosum (albinism)
fat benign tumor
causes of increased ESR
34. Sickle cell (altered shape) - polycythemia (too many) - CHF (unknown)
causes of decreased ESR
cigarette smoke target
intrinsic apoptosis
Leukocyte extravasation: rolling
35. AA
Leading cause of death in the US
CEA
asbestos target
secondary amyloidosis (reactive systemic)
36. Rhabdomyoma
Autoimmune (Hashimoto's - myasthenia gravis)
Bombesin
skeletal muscle benign tumor
smooth muscle malignant tumor
37. ACTH or ACTH- like peptide
Leukocyte extravasation: diapedesis
NF1 gene
abl gene
paraneoplastic effects of small cell lung carcinoma
38. Restoration of normal structure - granulation tissue (vascularized + fibrosis) - abscess (fibrosis + pus) - fistula or scarring (collagen).
Resolution of inflammation
Irreversible - plasias
APC gene
Paget's bone disease
39. Lung - breast - skin (melanoma) - kidney (renal cell carcinoma) - GI.50% brain tumors are from mets
aflatoxin target
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
smooth muscle malignant tumor
Primary tumors that met to brain
40. Neurofibromatosis type 1 17q tumor suppressor
breast cancer incidence/mortality
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.
paraneoplastic effects of leukemias and lymphomas
NF1 gene
41. GIST cytokine receptor (oncogene)
c - kit gene
Primary tumors that met to liver
Where you see Psammoma bodies
p16 gene
42. Vascular: E and P- selectin Leukocyte: Sialyl Lewis
Leukocyte extravasation: rolling
BRAC2 gene
Acute inflammatory mediators
NF1 gene
43. Melanoma 9p tumor suppressor
p16 gene
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)
DPC gene
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants
44. TB - fungal infections - syphilis - leprosy - cat scratch fever - sarcoid - Crohn's - Berylliosis.
N- myc gene
malignant >1 cell type tumor
granulomatous disease
Red (hemorrhagic) infarcts
45. Macrophages and lymphocytes. Persistant destruction and repair.
Primary tumors that met to liver
Chronic inflammatory mediators
benign >1 cell type tumor
fat benign tumor
46. Female 13%/23% and rising Male 16%/33% (mortality has plateaued)
abl gene
Irreversible - plasias
prostate cancer incidence/mortality
lung cancer incidence/mortality
47. Heart disease
ras gene
Napthalene (aniline) dyes target
Leading cause of death in the US
Necrosis
48. During embryogenesis - hormone induction and atrophy. Increased mitochondrial permeability and cytochrome c release. Increase Bax (pro - apoptotic) - decreased Bcl -2 (anti - apopotic).
Leukocyte extravasation: rolling
Leukocyte extravasation: tight binding
alpha - fetoprotein
intrinsic apoptosis
49. Angiosarcoma
blood cell malignant tumors
smooth muscle benign tumor
blood vessels malignant tumor
p53 gene
50. Colon carcinoma GTPase (oncogene)
Resolution of inflammation
nitrosamines (smoked foods) target
ras gene
bone malignant tumor