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First Aid Basics

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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Tumor marker: carcinoembryonic Ag Very nonspecific

2. Colonic adenocarcinoma

3. Tumor marker: tartrate - resistant acid phosphatase. Hairy cell leukemia (B- cell neoplasm)

4. CML tyrosine kinase (oncogene)

5. Breast cancer 13q tumor suppressor (DNA repair protein)

6. Neurofibromatosis type 2 22q tumor suppressor (key type 2=22)

7. Tumor marker: prostate carcinoma marker.

8. Hemangioma

9. Melanoma 9p tumor suppressor

10. Wilms' tumor 11p tumor suppressor

11. Rhabdomyoma

12. PECAM-1

13. Tumor marker: Screen for prostate carcinoma. Can also be elevated in BPH and prostatitis.

14. All - AML

15. Retinoblastoma - osteosarcoma 13q tumor suppressor (blocks G1 to S phase progression)

16. Enzymatic degradation and protein denaturation due to exogenous injury. Inflammatory process where intracellular components extravasate.

17. Secondary osteosarcoma and fibrosarcoma

18. Squamous cell carcinoma of skin

19. Astrocytoma - angiomyolipoma - cardiac rhabdomyoma

20. Erythropoietin

21. Colon cancer (Deleted in Colon Cancer) 18q tumor suppressor

22. Rhabdomyosarcoma

23. Squamous cell carcinoma of the esophagus

24. ACTH or ACTH- like peptide

25. Bladder (transitional cell carcinoma)

26. Infections - inflammation - cancer - pregnancy - SLE

27. Esophagus - stomach

28. Gastric adenocacinoma

29. Liver (centrilobular necrosis - fatty change)

30. Vascular: ICAM-1 Leukocyte: LFA-1 (integrin)

31. Pancreatic cancer (Deleted in Pancreatic Cancer) 18q tumor suppressor

32. Colorectal cancer (assoc with FAP) 5q tumor suppressor

33. GIST cytokine receptor (oncogene)

34. Tumor marker: pancreatic adenocarcinoma

35. Tumor marker: neuroblastoma - lung and gastric cancer

36. Adenoma - papilloma

37. Caused by peroxidation of membrane lipids. Causes acute gastric bleeding and chronic metabolic acidosis and scarring.

38. Tumor marker: thyroid medullary carcinoma

39. 32%/13% male

40. Hyperuricemia (excess NA turnover)

41. Lung (mesothelioma and bronchogenic carcinoma)

42. 32%/18% female

43. Melanoma - basal cell carcinoma - and especially squamous cell carcinomas of the skin.

44. Esophageal adenocarcinoma

45. Lipoma

46. Tumor marker: melanoma - neural tumors - astrocytomas

47. Ligand - receptor interactions. Release of perforin and granzyme B.

48. Antibodies to presynaptic Ca2+ channels at NM junction

49. Breast and ovarian cancer 17q tumor suppressor (DNA repair protein)

50. MEN type II and III tyrosine kinase (oncogene)