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First Aid Basics

Subjects : health-sciences, first-aid

Instructions:

Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can study here.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Ligand - receptor interactions. Release of perforin and granzyme B.
Alk - phos
extrinsic apoptosis
breast cancer incidence/mortality
Second - leading cause of death in the US

2. PTH- related peptide - TGF- beta - TNF - IL-1
Second - leading cause of death in the US
smooth muscle benign tumor
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.
smooth muscle malignant tumor

3. Breast - ovarian and gastric carcinomas tyrosine kinase (oncogene)
NF1 gene
erb - B2 gene
primary amyloidosis
extrinsic apoptosis

4. Osteoma
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants
Chronic inflammatory mediators
bone benign tumor
NF2 gene

5. Breast and ovarian cancer 17q tumor suppressor (DNA repair protein)
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)
BRCA1 gene
Leading cause of death in the US
Free radical cell damage

6. Tumor marker: melanoma - neural tumors - astrocytomas
S-100
NF2 gene
bcl -2 gene
Alkylating agents target

7. Angiosarcoma
blood vessels malignant tumor
Chronic inflammatory mediators
Pale infarcts
N- myc gene

8. Follicular and undifferentiated lymphomas anti - apoptotic molecule (oncogene)
bcl -2 gene
c - myc gene
benign epithelial tumor
paraneoplastic effects of leukemias and lymphomas

9. Mature teratoma in men or malignant teratoma in M/F
malignant >1 cell type tumor
Leading cause of death in the US
granulomatous disease
Necrosis

10. Burkitt's lymphoma transcription factor (oncogene)
c - myc gene
WT1 gene
malignant epithelial tumor
Leukocyte extravasation: tight binding

11. Blood (leukemia)
fat benign tumor
L- myc gene
Alkylating agents target
Paget's bone disease

12. Mature teratoma in women
smooth muscle benign tumor
CA-125
cirrosis (alcohol - hepB or C)
benign >1 cell type tumor

13. Enzymatic degradation and protein denaturation due to exogenous injury. Inflammatory process where intracellular components extravasate.
Necrosis
Prostatic acid phosphatase
asbestos target
paraneoplastic effects of renal cell carcinoma - hemangioblastoma

14. Bacterial products (CLIK):C5a - LTB4 - IL-8 - Kallikrein
Reversible - plasias
alpha - fetoprotein
Leukocyte extravasation: migration
CCl4 target

15. GIST cytokine receptor (oncogene)
smooth muscle benign tumor
c - kit gene
Bombesin
NF1 gene

16. Lung - breast - skin (melanoma) - kidney (renal cell carcinoma) - GI.50% brain tumors are from mets
Primary tumors that met to liver
Chronic inflammatory mediators
Primary tumors that met to brain
Neoplasm associated with actinic keratosis

17. Vascular: ICAM-1 Leukocyte: LFA-1 (integrin)
causes of decreased ESR
Leukocyte extravasation: tight binding
blood vessels benign tumor
benign epithelial tumor

18. Gastric adenocacinoma
CA-125
DPC gene
Rb gene
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants

19. Female 13%/23% and rising Male 16%/33% (mortality has plateaued)
lung cancer incidence/mortality
ulcerative colitis
Chronic inflammatory mediators
Leading cause of death in the US

20. Neuroblastoma transcription factor (oncogene)
N- myc gene
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
granulomatous disease
Free radical eliminators

21. Adenocarcinoma - papillary carcinoma
cirrosis (alcohol - hepB or C)
WT1 gene
Neoplasm associated with xeroderma pigmentosum (albinism)
malignant epithelial tumor

22. Tumor marker: pancreatic adenocarcinoma
PSA
calcitonin
CA-19-9
bcl -2 gene

23. Macrophages and lymphocytes. Persistant destruction and repair.
Chronic inflammatory mediators
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms
Barrett's esophagus (chronic GI reflux)
DPC gene

24. Colorectal cancer (assoc with FAP) 5q tumor suppressor
paraneoplastic effects of leukemias and lymphomas
lung cancer incidence/mortality
APC gene
p53 gene

25. Neurofibromatosis type 2 22q tumor suppressor (key type 2=22)
NF2 gene
DPC gene
malignant epithelial tumor
Autoimmune (Hashimoto's - myasthenia gravis)

26. 32%/13% male
Rb gene
prostate cancer incidence/mortality
extrinsic apoptosis
PSA

27. Rhabdomyosarcoma
Autoimmune (Hashimoto's - myasthenia gravis)
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants
skeletal muscle malignant tumor
iron poisoning

28. Papillary (thyroid) - Serous (ovary) - Meningioma - Mesothelioma
vinyl chloride target
benign epithelial tumor
Where you see Psammoma bodies
arsenic target

29. Neurofibromatosis type 1 17q tumor suppressor
malignant mesenchyme tumor (general)
APC gene
NF1 gene
Rb gene

30. Restoration of normal structure - granulation tissue (vascularized + fibrosis) - abscess (fibrosis + pus) - fistula or scarring (collagen).
ras gene
Resolution of inflammation
paraneoplastic effects of small cell lung carcinoma
calcitonin

31. Astrocytoma - angiomyolipoma - cardiac rhabdomyoma
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)
arsenic target
vinyl chloride target

32. PECAM-1
Bombesin
Leukocyte extravasation: diapedesis
arsenic target
primary amyloidosis

33. Bladder (transitional cell carcinoma)
CEA
blood vessels benign tumor
acanthosis nigricans (hyperpig and epidermal thickening)
Napthalene (aniline) dyes target

34. Pancreatic cancer (Deleted in Pancreatic Cancer) 18q tumor suppressor
cirrosis (alcohol - hepB or C)
DPC gene
Rb gene
granulomatous disease

35. MEN type II and III tyrosine kinase (oncogene)
ret gene
fat benign tumor
granulomatous disease
Neoplasm associated with actinic keratosis

36. Melanoma 9p tumor suppressor
p16 gene
abl gene
alpha - fetoprotein
c - myc gene

37. During embryogenesis - hormone induction and atrophy. Increased mitochondrial permeability and cytochrome c release. Increase Bax (pro - apoptotic) - decreased Bcl -2 (anti - apopotic).
extrinsic apoptosis
paraneoplastic effects of thymoma - small cell lung carcinoma
blood cell malignant tumors
intrinsic apoptosis

38. Rhabdomyoma
skeletal muscle benign tumor
WT1 gene
abl gene
iron poisoning

39. Lymphoma

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40. 32%/18% female
paraneoplastic effects of small cell lung carcinoma
blood cell malignant tumors
Rb gene
breast cancer incidence/mortality

41. Lung - liver - intestine or following reperfusion.
Red (hemorrhagic) infarcts
asbestos target
BRCA1 gene
CEA

42. Tumor marker: mets to bone - obstructive biliary disease - Paget's
APC gene
Alk - phos
smooth muscle malignant tumor
Neoplasm associated with Down Syndrome

43. Adenoma - papilloma
c - myc gene
benign epithelial tumor
fat malignant tumor
NF2 gene

44. Lipoma
granulomatous disease
causes of decreased ESR
fat benign tumor
WT1 gene

45. Hyperuricemia (excess NA turnover)
paraneoplastic effects of leukemias and lymphomas
causes of increased ESR
L- myc gene
Pale infarcts

46. Visceral malignancy (stomach - lung - breast - uterus)
smooth muscle benign tumor
acanthosis nigricans (hyperpig and epidermal thickening)
Colon and rectal cancer incidence
BRAC2 gene

47. ACTH or ACTH- like peptide
paraneoplastic effects of small cell lung carcinoma
Leukocyte extravasation: diapedesis
Free radical eliminators
Colon and rectal cancer incidence

48. CML tyrosine kinase (oncogene)
Pale infarcts
abl gene
benign epithelial tumor
Leukocyte extravasation: diapedesis

49. Colonic adenocarcinoma
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
ulcerative colitis
BRCA1 gene
causes of decreased ESR

50. Aggressive malignant lymphomas (non - Hodgkin's) and Kaposi's sarcoma
ras gene
p53 gene
AIDS
immunodeficiency states