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First Aid Basics

Subjects : health-sciences, first-aid

Instructions:

Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can study here.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. CML tyrosine kinase (oncogene)
breast cancer incidence/mortality
DPC gene
AIDS
abl gene

2. Malignant lymphoma
breast cancer incidence/mortality
CCl4 target
immunodeficiency states
Resolution of inflammation

3. Retinoblastoma - osteosarcoma 13q tumor suppressor (blocks G1 to S phase progression)
ret gene
Red (hemorrhagic) infarcts
Rb gene
Chronic inflammatory mediators

4. Angiosarcoma
Primary tumors that met to brain
blood vessels malignant tumor
benign >1 cell type tumor
cirrosis (alcohol - hepB or C)

5. Secondary osteosarcoma and fibrosarcoma

6. Sarcoma - papillary thyroid cancer
cigarette smoke target
vinyl chloride target
prostate cancer incidence/mortality
radiation exposure

7. AL
primary amyloidosis
fat benign tumor
paraneoplastic effects of thymoma - small cell lung carcinoma
ulcerative colitis

8. Lymphoma

9. Malignant melanoma
Alkylating agents target
Resolution of inflammation
dysplastic nevus
Reversible - plasias

10. Restoration of normal structure - granulation tissue (vascularized + fibrosis) - abscess (fibrosis + pus) - fistula or scarring (collagen).
ret gene
Resolution of inflammation
malignant mesenchyme tumor (general)
cirrosis (alcohol - hepB or C)

11. Neurofibromatosis type 1 17q tumor suppressor
skeletal muscle malignant tumor
arsenic target
NF1 gene
S-100

12. Vascular: ICAM-1 Leukocyte: LFA-1 (integrin)
ras gene
aflatoxin target
paraneoplastic effects of leukemias and lymphomas
Leukocyte extravasation: tight binding

13. Hyperuricemia (excess NA turnover)
S-100
blood cell malignant tumors
radiation exposure
paraneoplastic effects of leukemias and lymphomas

14. Prostate (blastic) - thyroid - testes - breast (lytic and blastic) - lung (lytic) - kidney (breast and prostate are most common)
BRCA1 gene
beta - hCG
Primary tumors that met to bone
fat malignant tumor

15. Infections - inflammation - cancer - pregnancy - SLE
Red (hemorrhagic) infarcts
Neoplasm associated with xeroderma pigmentosum (albinism)
lung cancer incidence/mortality
causes of increased ESR

16. Hepatocellular carcinoma
radiation exposure
paraneoplastic effects of thymoma - small cell lung carcinoma
cirrosis (alcohol - hepB or C)
Alk - phos

17. PECAM-1
Leukocyte extravasation: diapedesis
smooth muscle benign tumor
Resolution of inflammation
intrinsic apoptosis

18. Papillary (thyroid) - Serous (ovary) - Meningioma - Mesothelioma
Primary tumors that met to brain
Where you see Psammoma bodies
Primary tumors that met to liver
paraneoplastic effects of renal cell carcinoma - hemangioblastoma

19. PTH- related peptide - TGF- beta - TNF - IL-1
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.
granulomatous disease
AIDS
Alkylating agents target

20. Tumor marker: (Normal in fetus). Hepatocellular carcinomas. Nonseminomatous germ cell tumors of the testis.
Red (hemorrhagic) infarcts
TRAP
alpha - fetoprotein
Barrett's esophagus (chronic GI reflux)

21. Neutrophils (eos in the gut) - plus other granular leukocytes and antibodies.
bone benign tumor
Acute inflammatory mediators
WT1 gene
BRCA1 gene

22. Rhabdomyoma
skeletal muscle benign tumor
Autoimmune (Hashimoto's - myasthenia gravis)
CA-125
lung cancer incidence/mortality

23. Lung - breast - skin (melanoma) - kidney (renal cell carcinoma) - GI.50% brain tumors are from mets
granulomatous disease
CCl4 target
cirrosis (alcohol - hepB or C)
Primary tumors that met to brain

24. Adenoma - papilloma
blood vessels malignant tumor
benign epithelial tumor
blood cell malignant tumors
fat benign tumor

25. Caused by peroxidation of membrane lipids. Causes acute gastric bleeding and chronic metabolic acidosis and scarring.
fat benign tumor
iron poisoning
aflatoxin target
Primary tumors that met to bone

26. Colorectal cancer (assoc with FAP) 5q tumor suppressor
Primary tumors that met to bone
Paget's bone disease
Autoimmune (Hashimoto's - myasthenia gravis)
APC gene

27. Esophagus - stomach
DPC gene
nitrosamines (smoked foods) target
benign epithelial tumor
fat malignant tumor

28. Melanoma 9p tumor suppressor
N- myc gene
BRAC2 gene
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)
p16 gene

29. Osteoma
bone benign tumor
skeletal muscle malignant tumor
BRCA1 gene
Primary tumors that met to bone

30. MEN type II and III tyrosine kinase (oncogene)
ret gene
Neoplasm associated with xeroderma pigmentosum (albinism)
erb - B2 gene
L- myc gene

31. Pancreatic cancer (Deleted in Pancreatic Cancer) 18q tumor suppressor
L- myc gene
DPC gene
Paget's bone disease
CEA

32. Osteosarcoma
acanthosis nigricans (hyperpig and epidermal thickening)
Neoplasm associated with xeroderma pigmentosum (albinism)
BRCA1 gene
bone malignant tumor

33. Sarcoma
malignant mesenchyme tumor (general)
BRAC2 gene
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
skeletal muscle malignant tumor

34. Cancer
Second - leading cause of death in the US
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)
bcl -2 gene
Free radical eliminators

35. Tumor marker: prostate carcinoma marker.
beta - hCG
Autoimmune (Hashimoto's - myasthenia gravis)
calcitonin
Prostatic acid phosphatase

36. Sickle cell (altered shape) - polycythemia (too many) - CHF (unknown)
Alkylating agents target
causes of decreased ESR
immunodeficiency states
Free radical cell damage

37. Macrophages and lymphocytes. Persistant destruction and repair.
S-100
Prostatic acid phosphatase
Bombesin
Chronic inflammatory mediators

38. Tumor marker: ovarian - malignant epithelial tumors.
NF2 gene
intrinsic apoptosis
CA-125
bone malignant tumor

39. Ligand - receptor interactions. Release of perforin and granzyme B.
Neoplasm associated with actinic keratosis
S-100
extrinsic apoptosis
prostate cancer incidence/mortality

40. Heart disease
Leading cause of death in the US
paraneoplastic effects of small cell lung carcinoma
granulomatous disease
prostate cancer incidence/mortality

41. Wilms' tumor 11p tumor suppressor
paraneoplastic effects of leukemias and lymphomas
causes of decreased ESR
blood vessels benign tumor
WT1 gene

42. Membrane lipid peroxidation - protein modification and DNA breakage.
DCC gene
Leukocyte extravasation: migration
prostate cancer incidence/mortality
Free radical cell damage

43. Leiomyoma
blood vessels malignant tumor
granulomatous disease
smooth muscle benign tumor
beta - hCG

44. Bacterial products (CLIK):C5a - LTB4 - IL-8 - Kallikrein
arsenic target
Leukocyte extravasation: tight binding
malignant epithelial tumor
Leukocyte extravasation: migration

45. Tumor marker: thyroid medullary carcinoma
calcitonin
ras gene
paraneoplastic effects of thymoma - small cell lung carcinoma
AIDS

46. Hyperplasia - metaplasia - dysplasia
Reversible - plasias
DCC gene
primary amyloidosis
nitrosamines (smoked foods) target

47. Tumor marker: Screen for prostate carcinoma. Can also be elevated in BPH and prostatitis.
PSA
Napthalene (aniline) dyes target
erb - B2 gene
ras gene

48. ADH
p16 gene
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)
ras gene
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms

49. Blood (leukemia)
Second - leading cause of death in the US
cirrosis (alcohol - hepB or C)
beta - hCG
Alkylating agents target

50. Tumor marker: tartrate - resistant acid phosphatase. Hairy cell leukemia (B- cell neoplasm)
paraneoplastic effects of small cell lung carcinoma
TRAP
WT1 gene
malignant epithelial tumor