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First Aid Basics

Subjects : health-sciences, first-aid

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Anaplasia - neoplasia - desmoplasia (fibrous tissue formation in response to neoplasm)
c - kit gene
Irreversible - plasias
DPC gene
dysplastic nevus

2. Retinoblastoma - osteosarcoma 13q tumor suppressor (blocks G1 to S phase progression)
Chronic inflammatory mediators
fat malignant tumor
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
Rb gene

3. Hyperuricemia (excess NA turnover)
paraneoplastic effects of leukemias and lymphomas
Chronic inflammatory mediators
malignant mesenchyme tumor (general)
cirrosis (alcohol - hepB or C)

4. Lung - breast - skin (melanoma) - kidney (renal cell carcinoma) - GI.50% brain tumors are from mets
Primary tumors that met to brain
dysplastic nevus
smooth muscle malignant tumor
paraneoplastic effects of small cell lung carcinoma

5. Membrane lipid peroxidation - protein modification and DNA breakage.
secondary amyloidosis (reactive systemic)
Reversible - plasias
breast cancer incidence/mortality
Free radical cell damage

6. PTH- related peptide - TGF- beta - TNF - IL-1
Free radical eliminators
CCl4 target
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.
Primary tumors that met to brain

7. Cancer
vinyl chloride target
N- myc gene
DCC gene
Second - leading cause of death in the US

8. Gastric adenocacinoma
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants
S-100
prostate cancer incidence/mortality
Neoplasm associated with actinic keratosis

9. Most human cancers - specifically Li - Fraumeni syndrome 17p tumor suppressor (blocks G1 to S phase progression)
extrinsic apoptosis
Neoplasm associated with xeroderma pigmentosum (albinism)
p53 gene
Neoplasm associated with Down Syndrome

10. Hemangioma
DPC gene
blood vessels benign tumor
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms
secondary amyloidosis (reactive systemic)

11. Lymphoma

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12. Melanoma 9p tumor suppressor
Autoimmune (Hashimoto's - myasthenia gravis)
DPC gene
dysplastic nevus
p16 gene

13. Liver (angiosarcoma)
Leukocyte extravasation: diapedesis
malignant >1 cell type tumor
vinyl chloride target
abl gene

14. Secondary osteosarcoma and fibrosarcoma

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15. Aggressive malignant lymphomas (non - Hodgkin's) and Kaposi's sarcoma
cigarette smoke target
AIDS
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)
benign epithelial tumor

16. Tumor marker: tartrate - resistant acid phosphatase. Hairy cell leukemia (B- cell neoplasm)
p53 gene
TRAP
lung cancer incidence/mortality
extrinsic apoptosis

17. Colon>stomach>pancreas>breast>lung (liver and lung are the most common places for mets)
Autoimmune (Hashimoto's - myasthenia gravis)
lung cancer incidence/mortality
c - myc gene
Primary tumors that met to liver

18. Astrocytoma - angiomyolipoma - cardiac rhabdomyoma
smooth muscle malignant tumor
granulomatous disease
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)
Second - leading cause of death in the US

19. Visceral malignancy (stomach - lung - breast - uterus)
CEA
bcl -2 gene
Neoplasm associated with xeroderma pigmentosum (albinism)
acanthosis nigricans (hyperpig and epidermal thickening)

20. Vascular: E and P- selectin Leukocyte: Sialyl Lewis
Leukocyte extravasation: rolling
bone malignant tumor
p16 gene
causes of decreased ESR

21. Skin (SqCC) - liver (angiosarcoma)
arsenic target
Second - leading cause of death in the US
smooth muscle benign tumor
skeletal muscle malignant tumor

22. Hepatocellular carcinoma
cirrosis (alcohol - hepB or C)
CA-19-9
prostate cancer incidence/mortality
N- myc gene

23. Vascular: ICAM-1 Leukocyte: LFA-1 (integrin)
WT1 gene
ret gene
intrinsic apoptosis
Leukocyte extravasation: tight binding

24. Colonic adenocarcinoma
lung cancer incidence/mortality
smooth muscle benign tumor
ulcerative colitis
Rb gene

25. ADH
PSA
intrinsic apoptosis
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms
Neoplasm associated with Down Syndrome

26. Restoration of normal structure - granulation tissue (vascularized + fibrosis) - abscess (fibrosis + pus) - fistula or scarring (collagen).
ret gene
Resolution of inflammation
c - myc gene
CA-19-9

27. Esophageal adenocarcinoma

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28. Liver (hepatocellular carcinoma)
Neoplasm associated with xeroderma pigmentosum (albinism)
aflatoxin target
APC gene
nitrosamines (smoked foods) target

29. Breast - ovarian and gastric carcinomas tyrosine kinase (oncogene)
CCl4 target
beta - hCG
lung cancer incidence/mortality
erb - B2 gene

30. Solid tissues with single blood supply. Heart - kidney and spleen.
Pale infarcts
causes of decreased ESR
blood vessels benign tumor
Paget's bone disease

31. ACTH or ACTH- like peptide
paraneoplastic effects of small cell lung carcinoma
asbestos target
Alkylating agents target
Colon and rectal cancer incidence

32. Larynx (SqCC) - lung (SqCC and SCC) - kidney (renal cell carcinoma) - bladder (transitional cell carcinoma)
cigarette smoke target
Free radical cell damage
Alk - phos
Colon and rectal cancer incidence

33. Mature teratoma in men or malignant teratoma in M/F
erb - B2 gene
arsenic target
ras gene
malignant >1 cell type tumor

34. Infections - inflammation - cancer - pregnancy - SLE
N- myc gene
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.
cigarette smoke target
causes of increased ESR

35. Adenoma - papilloma
benign epithelial tumor
skeletal muscle benign tumor
Pale infarcts
Paget's bone disease

36. Heart disease
Primary tumors that met to brain
Napthalene (aniline) dyes target
Leading cause of death in the US
CA-125

37. 32%/13% male
c - myc gene
CEA
prostate cancer incidence/mortality
bone malignant tumor

38. Caused by peroxidation of membrane lipids. Causes acute gastric bleeding and chronic metabolic acidosis and scarring.
PSA
Primary tumors that met to bone
Neoplasm associated with Down Syndrome
iron poisoning

39. Female 13% Male 12%
BRCA1 gene
cigarette smoke target
TRAP
Colon and rectal cancer incidence

40. Rhabdomyoma
Acute inflammatory mediators
NF2 gene
Leukocyte extravasation: rolling
skeletal muscle benign tumor

41. AL
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
primary amyloidosis
Neoplasm associated with Down Syndrome
prostate cancer incidence/mortality

42. Tumor marker: thyroid medullary carcinoma
smooth muscle benign tumor
calcitonin
Neoplasm associated with actinic keratosis
iron poisoning

43. Tumor marker: neuroblastoma - lung and gastric cancer
L- myc gene
Bombesin
PSA
causes of increased ESR

44. PECAM-1
CA-19-9
Leukocyte extravasation: diapedesis
benign epithelial tumor
paraneoplastic effects of small cell lung carcinoma

45. TB - fungal infections - syphilis - leprosy - cat scratch fever - sarcoid - Crohn's - Berylliosis.
Acute inflammatory mediators
granulomatous disease
asbestos target
Red (hemorrhagic) infarcts

46. CML tyrosine kinase (oncogene)
malignant >1 cell type tumor
abl gene
Resolution of inflammation
Leukocyte extravasation: rolling

47. Melanoma - basal cell carcinoma - and especially squamous cell carcinomas of the skin.
Neoplasm associated with xeroderma pigmentosum (albinism)
blood cell malignant tumors
Reversible - plasias
N- myc gene

48. Pancreatic cancer (Deleted in Pancreatic Cancer) 18q tumor suppressor
Free radical cell damage
NF2 gene
intrinsic apoptosis
DPC gene

49. Tumor marker: ovarian - malignant epithelial tumors.
Autoimmune (Hashimoto's - myasthenia gravis)
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)
CA-125
primary amyloidosis

50. Breast and ovarian cancer 17q tumor suppressor (DNA repair protein)
BRAC2 gene
BRCA1 gene
AIDS
radiation exposure

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First Aid Basics

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