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First Aid Basics

Subjects : health-sciences, first-aid

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Tumor marker: carcinoembryonic Ag Very nonspecific
Acute inflammatory mediators
N- myc gene
Barrett's esophagus (chronic GI reflux)
CEA

2. Leukemia - lymphoma
ras gene
malignant mesenchyme tumor (general)
blood cell malignant tumors
Paget's bone disease

3. Lung (mesothelioma and bronchogenic carcinoma)
asbestos target
aflatoxin target
WT1 gene
NF2 gene

4. Tumor marker: tartrate - resistant acid phosphatase. Hairy cell leukemia (B- cell neoplasm)
p53 gene
TRAP
blood vessels benign tumor
paraneoplastic effects of leukemias and lymphomas

5. Aggressive malignant lymphomas (non - Hodgkin's) and Kaposi's sarcoma
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.
AIDS
Primary tumors that met to bone
smooth muscle malignant tumor

6. Hepatocellular carcinoma
cirrosis (alcohol - hepB or C)
DCC gene
NF2 gene
CEA

7. Leiomyoma
Irreversible - plasias
smooth muscle benign tumor
c - kit gene
iron poisoning

8. Follicular and undifferentiated lymphomas anti - apoptotic molecule (oncogene)
Neoplasm associated with actinic keratosis
TRAP
bcl -2 gene
Alk - phos

9. Squamous cell carcinoma of skin
bone malignant tumor
L- myc gene
Neoplasm associated with actinic keratosis
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants

10. ADH
intrinsic apoptosis
aflatoxin target
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms
Red (hemorrhagic) infarcts

11. Hemangioma
blood vessels benign tumor
Barrett's esophagus (chronic GI reflux)
Neoplasm associated with actinic keratosis
Red (hemorrhagic) infarcts

12. Wilms' tumor 11p tumor suppressor
smooth muscle malignant tumor
Alk - phos
causes of increased ESR
WT1 gene

13. Colorectal cancer (assoc with FAP) 5q tumor suppressor
Leukocyte extravasation: tight binding
Where you see Psammoma bodies
APC gene
S-100

14. PECAM-1
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)
WT1 gene
Leukocyte extravasation: diapedesis
NF2 gene

15. Melanoma 9p tumor suppressor
Where you see Psammoma bodies
p16 gene
aflatoxin target
paraneoplastic effects of small cell lung carcinoma

16. Hyperuricemia (excess NA turnover)
Where you see Psammoma bodies
vinyl chloride target
primary amyloidosis
paraneoplastic effects of leukemias and lymphomas

17. Sarcoma - papillary thyroid cancer
BRAC2 gene
radiation exposure
Second - leading cause of death in the US
smooth muscle malignant tumor

18. Bacterial products (CLIK):C5a - LTB4 - IL-8 - Kallikrein
N- myc gene
Leukocyte extravasation: migration
paraneoplastic effects of thymoma - small cell lung carcinoma
Leading cause of death in the US

19. Caused by peroxidation of membrane lipids. Causes acute gastric bleeding and chronic metabolic acidosis and scarring.
iron poisoning
smooth muscle benign tumor
fat malignant tumor
secondary amyloidosis (reactive systemic)

20. Liver (angiosarcoma)
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.
vinyl chloride target
Prostatic acid phosphatase
Neoplasm associated with xeroderma pigmentosum (albinism)

21. All - AML
primary amyloidosis
CEA
Alk - phos
Neoplasm associated with Down Syndrome

22. Skin (SqCC) - liver (angiosarcoma)
nitrosamines (smoked foods) target
arsenic target
malignant mesenchyme tumor (general)
CCl4 target

23. Tumor marker: prostate carcinoma marker.
Free radical cell damage
Leukocyte extravasation: migration
Prostatic acid phosphatase
Free radical eliminators

24. 32%/18% female
CA-125
Barrett's esophagus (chronic GI reflux)
Free radical eliminators
breast cancer incidence/mortality

25. Lung - breast - skin (melanoma) - kidney (renal cell carcinoma) - GI.50% brain tumors are from mets
Acute inflammatory mediators
Primary tumors that met to brain
Free radical cell damage
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)

26. Female 13% Male 12%
intrinsic apoptosis
Paget's bone disease
Colon and rectal cancer incidence
vinyl chloride target

27. Neurofibromatosis type 1 17q tumor suppressor
BRCA1 gene
causes of increased ESR
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.
NF1 gene

28. Infections - inflammation - cancer - pregnancy - SLE
c - myc gene
causes of increased ESR
Primary tumors that met to brain
PSA

29. Colonic adenocarcinoma
ulcerative colitis
benign >1 cell type tumor
Leukocyte extravasation: tight binding
Leading cause of death in the US

30. Pancreatic cancer (Deleted in Pancreatic Cancer) 18q tumor suppressor
Paget's bone disease
DPC gene
ret gene
Alk - phos

31. Hyperplasia - metaplasia - dysplasia
paraneoplastic effects of small cell lung carcinoma
nitrosamines (smoked foods) target
CA-19-9
Reversible - plasias

32. Neutrophils (eos in the gut) - plus other granular leukocytes and antibodies.
beta - hCG
WT1 gene
Acute inflammatory mediators
blood vessels malignant tumor

33. Anaplasia - neoplasia - desmoplasia (fibrous tissue formation in response to neoplasm)
Irreversible - plasias
TRAP
Alk - phos
radiation exposure

34. MEN type II and III tyrosine kinase (oncogene)
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms
ret gene
benign epithelial tumor
TRAP

35. Prostate (blastic) - thyroid - testes - breast (lytic and blastic) - lung (lytic) - kidney (breast and prostate are most common)
fat benign tumor
cigarette smoke target
Primary tumors that met to bone
p16 gene

36. AA
ulcerative colitis
secondary amyloidosis (reactive systemic)
cigarette smoke target
malignant >1 cell type tumor

37. Heart disease
DCC gene
fat benign tumor
Leading cause of death in the US
Irreversible - plasias

38. Tumor marker: Screen for prostate carcinoma. Can also be elevated in BPH and prostatitis.
PSA
APC gene
dysplastic nevus
Colon and rectal cancer incidence

39. Neuroblastoma transcription factor (oncogene)
N- myc gene
fat benign tumor
Where you see Psammoma bodies
malignant epithelial tumor

40. Mature teratoma in men or malignant teratoma in M/F
malignant >1 cell type tumor
Pale infarcts
Leukocyte extravasation: rolling
alpha - fetoprotein

41. 32%/13% male
Neoplasm associated with Down Syndrome
AIDS
prostate cancer incidence/mortality
alpha - fetoprotein

42. Ligand - receptor interactions. Release of perforin and granzyme B.
extrinsic apoptosis
Leukocyte extravasation: rolling
TRAP
blood vessels benign tumor

43. Sickle cell (altered shape) - polycythemia (too many) - CHF (unknown)
causes of decreased ESR
CCl4 target
Primary tumors that met to brain
Neoplasm associated with Down Syndrome

44. Rhabdomyosarcoma
alpha - fetoprotein
skeletal muscle malignant tumor
Primary tumors that met to bone
Colon and rectal cancer incidence

45. Colon>stomach>pancreas>breast>lung (liver and lung are the most common places for mets)
Primary tumors that met to liver
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants
Colon and rectal cancer incidence
Leukocyte extravasation: diapedesis

46. Tumor marker: Hydatifiform moles - choriocarcinomas - gestational trophoblastic tumors.
Napthalene (aniline) dyes target
CCl4 target
beta - hCG
PSA

47. Esophagus - stomach
nitrosamines (smoked foods) target
Pale infarcts
abl gene
N- myc gene

48. Membrane lipid peroxidation - protein modification and DNA breakage.
blood cell malignant tumors
Necrosis
N- myc gene
Free radical cell damage

49. Breast and ovarian cancer 17q tumor suppressor (DNA repair protein)
NF2 gene
acanthosis nigricans (hyperpig and epidermal thickening)
BRCA1 gene
APC gene

50. Retinoblastoma - osteosarcoma 13q tumor suppressor (blocks G1 to S phase progression)
Rb gene
p16 gene
malignant >1 cell type tumor
Alk - phos

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First Aid Basics

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