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First Aid Basics

Subjects : health-sciences, first-aid

Instructions:

Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can study here.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Malignant lymphoma
immunodeficiency states
erb - B2 gene
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
blood cell malignant tumors

2. AA
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms
aflatoxin target
Free radical eliminators
secondary amyloidosis (reactive systemic)

3. Breast - ovarian and gastric carcinomas tyrosine kinase (oncogene)
erb - B2 gene
radiation exposure
acanthosis nigricans (hyperpig and epidermal thickening)
AIDS

4. Tumor marker: Hydatifiform moles - choriocarcinomas - gestational trophoblastic tumors.
bone benign tumor
beta - hCG
c - myc gene
smooth muscle malignant tumor

5. Leiomyoma
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms
cirrosis (alcohol - hepB or C)
smooth muscle benign tumor
blood vessels benign tumor

6. Osteoma
bone benign tumor
Napthalene (aniline) dyes target
breast cancer incidence/mortality
causes of increased ESR

7. Neurofibromatosis type 1 17q tumor suppressor
NF1 gene
Leukocyte extravasation: rolling
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.
asbestos target

8. Melanoma - basal cell carcinoma - and especially squamous cell carcinomas of the skin.
L- myc gene
Alk - phos
CCl4 target
Neoplasm associated with xeroderma pigmentosum (albinism)

9. Anaplasia - neoplasia - desmoplasia (fibrous tissue formation in response to neoplasm)
smooth muscle benign tumor
Leading cause of death in the US
Irreversible - plasias
iron poisoning

10. Adenoma - papilloma
benign epithelial tumor
Primary tumors that met to bone
bone malignant tumor
ret gene

11. Solid tissues with single blood supply. Heart - kidney and spleen.
BRCA1 gene
Pale infarcts
aflatoxin target
Primary tumors that met to brain

12. Rhabdomyoma
paraneoplastic effects of leukemias and lymphomas
skeletal muscle benign tumor
bone benign tumor
malignant >1 cell type tumor

13. Pancreatic cancer (Deleted in Pancreatic Cancer) 18q tumor suppressor
dysplastic nevus
causes of decreased ESR
immunodeficiency states
DPC gene

14. Colorectal cancer (assoc with FAP) 5q tumor suppressor
APC gene
CCl4 target
Acute inflammatory mediators
c - myc gene

15. Lymphoma

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16. Tumor marker: (Normal in fetus). Hepatocellular carcinomas. Nonseminomatous germ cell tumors of the testis.
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants
lung cancer incidence/mortality
paraneoplastic effects of thymoma - small cell lung carcinoma
alpha - fetoprotein

17. Tumor marker: Screen for prostate carcinoma. Can also be elevated in BPH and prostatitis.
causes of decreased ESR
PSA
bone malignant tumor
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)

18. Secondary osteosarcoma and fibrosarcoma

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19. During embryogenesis - hormone induction and atrophy. Increased mitochondrial permeability and cytochrome c release. Increase Bax (pro - apoptotic) - decreased Bcl -2 (anti - apopotic).
intrinsic apoptosis
AIDS
Acute inflammatory mediators
Bombesin

20. Ligand - receptor interactions. Release of perforin and granzyme B.
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
CCl4 target
extrinsic apoptosis

21. Adenocarcinoma - papillary carcinoma
BRCA1 gene
malignant epithelial tumor
benign epithelial tumor
Leading cause of death in the US

22. Retinoblastoma - osteosarcoma 13q tumor suppressor (blocks G1 to S phase progression)
intrinsic apoptosis
CA-125
Leading cause of death in the US
Rb gene

23. Antibodies to presynaptic Ca2+ channels at NM junction
radiation exposure
cirrosis (alcohol - hepB or C)
p53 gene
paraneoplastic effects of thymoma - small cell lung carcinoma

24. Erythropoietin
CA-125
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
Colon and rectal cancer incidence
S-100

25. Tumor marker: carcinoembryonic Ag Very nonspecific
CEA
Leukocyte extravasation: tight binding
DCC gene
vinyl chloride target

26. Lung (mesothelioma and bronchogenic carcinoma)
asbestos target
Primary tumors that met to bone
ras gene
Leukocyte extravasation: diapedesis

27. Skin (SqCC) - liver (angiosarcoma)
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)
benign >1 cell type tumor
Bombesin
arsenic target

28. Vascular: E and P- selectin Leukocyte: Sialyl Lewis
abl gene
Leukocyte extravasation: rolling
prostate cancer incidence/mortality
L- myc gene

29. Aggressive malignant lymphomas (non - Hodgkin's) and Kaposi's sarcoma
Necrosis
vinyl chloride target
AIDS
L- myc gene

30. Lung - breast - skin (melanoma) - kidney (renal cell carcinoma) - GI.50% brain tumors are from mets
N- myc gene
Red (hemorrhagic) infarcts
nitrosamines (smoked foods) target
Primary tumors that met to brain

31. Most human cancers - specifically Li - Fraumeni syndrome 17p tumor suppressor (blocks G1 to S phase progression)
p53 gene
Bombesin
blood vessels malignant tumor
aflatoxin target

32. Vascular: ICAM-1 Leukocyte: LFA-1 (integrin)
PSA
CA-19-9
Paget's bone disease
Leukocyte extravasation: tight binding

33. Colonic adenocarcinoma
Leukocyte extravasation: rolling
NF2 gene
Leading cause of death in the US
ulcerative colitis

34. Enzymatic degradation and protein denaturation due to exogenous injury. Inflammatory process where intracellular components extravasate.
NF1 gene
lung cancer incidence/mortality
Neoplasm associated with Down Syndrome
Necrosis

35. Hyperuricemia (excess NA turnover)
beta - hCG
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms
intrinsic apoptosis
paraneoplastic effects of leukemias and lymphomas

36. Breast cancer 13q tumor suppressor (DNA repair protein)
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)
Leukocyte extravasation: migration
BRAC2 gene
erb - B2 gene

37. Liver (centrilobular necrosis - fatty change)
Resolution of inflammation
Leading cause of death in the US
Pale infarcts
CCl4 target

38. TB - fungal infections - syphilis - leprosy - cat scratch fever - sarcoid - Crohn's - Berylliosis.
bcl -2 gene
granulomatous disease
nitrosamines (smoked foods) target
Neoplasm associated with actinic keratosis

39. Prostate (blastic) - thyroid - testes - breast (lytic and blastic) - lung (lytic) - kidney (breast and prostate are most common)
vinyl chloride target
Leukocyte extravasation: rolling
Primary tumors that met to bone
radiation exposure

40. Bacterial products (CLIK):C5a - LTB4 - IL-8 - Kallikrein
Leukocyte extravasation: migration
BRCA1 gene
asbestos target
BRAC2 gene

41. Sickle cell (altered shape) - polycythemia (too many) - CHF (unknown)
Leukocyte extravasation: tight binding
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms
causes of decreased ESR
Alkylating agents target

42. Liposarcoma
alpha - fetoprotein
CCl4 target
fat malignant tumor
vinyl chloride target

43. Blood (leukemia)
Alkylating agents target
cigarette smoke target
lung cancer incidence/mortality
CCl4 target

44. Bladder (transitional cell carcinoma)
Napthalene (aniline) dyes target
calcitonin
Reversible - plasias
PSA

45. Tumor marker: mets to bone - obstructive biliary disease - Paget's
blood cell malignant tumors
Primary tumors that met to bone
Alk - phos
p53 gene

46. ADH
Rb gene
CA-19-9
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms
smooth muscle malignant tumor

47. Colon>stomach>pancreas>breast>lung (liver and lung are the most common places for mets)
Primary tumors that met to liver
breast cancer incidence/mortality
Napthalene (aniline) dyes target
extrinsic apoptosis

48. Neutrophils (eos in the gut) - plus other granular leukocytes and antibodies.
Acute inflammatory mediators
Neoplasm associated with xeroderma pigmentosum (albinism)
Primary tumors that met to liver
cigarette smoke target

49. Hyperplasia - metaplasia - dysplasia
p16 gene
S-100
Reversible - plasias
cirrosis (alcohol - hepB or C)

50. Gastric adenocacinoma
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms
arsenic target
DCC gene