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First Aid Basics

Subjects : health-sciences, first-aid

Instructions:

Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can study here.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Tumor marker: tartrate - resistant acid phosphatase. Hairy cell leukemia (B- cell neoplasm)
benign epithelial tumor
blood vessels malignant tumor
TRAP
malignant mesenchyme tumor (general)

2. Tumor marker: melanoma - neural tumors - astrocytomas
p16 gene
bone benign tumor
paraneoplastic effects of leukemias and lymphomas
S-100

3. Angiosarcoma
Autoimmune (Hashimoto's - myasthenia gravis)
blood vessels malignant tumor
ras gene
Chronic inflammatory mediators

4. Rhabdomyoma
skeletal muscle benign tumor
Free radical cell damage
S-100
Pale infarcts

5. Colonic adenocarcinoma
arsenic target
cigarette smoke target
Neoplasm associated with xeroderma pigmentosum (albinism)
ulcerative colitis

6. Tumor marker: pancreatic adenocarcinoma
abl gene
Irreversible - plasias
smooth muscle malignant tumor
CA-19-9

7. Tumor marker: carcinoembryonic Ag Very nonspecific
acanthosis nigricans (hyperpig and epidermal thickening)
AIDS
CEA
ras gene

8. Liver (hepatocellular carcinoma)
aflatoxin target
Leukocyte extravasation: rolling
bone benign tumor
benign epithelial tumor

9. Colorectal cancer (assoc with FAP) 5q tumor suppressor
arsenic target
CA-19-9
CEA
APC gene

10. PTH- related peptide - TGF- beta - TNF - IL-1
NF2 gene
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
primary amyloidosis

11. Bacterial products (CLIK):C5a - LTB4 - IL-8 - Kallikrein
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants
dysplastic nevus
bone benign tumor
Leukocyte extravasation: migration

12. Lipoma
fat benign tumor
Pale infarcts
CA-19-9
Where you see Psammoma bodies

13. All - AML
beta - hCG
Paget's bone disease
Neoplasm associated with Down Syndrome
smooth muscle malignant tumor

14. Breast and ovarian cancer 17q tumor suppressor (DNA repair protein)
L- myc gene
BRCA1 gene
fat benign tumor
paraneoplastic effects of renal cell carcinoma - hemangioblastoma

15. Vascular: ICAM-1 Leukocyte: LFA-1 (integrin)
Leukocyte extravasation: tight binding
Leukocyte extravasation: migration
Neoplasm associated with xeroderma pigmentosum (albinism)
Leukocyte extravasation: diapedesis

16. Most human cancers - specifically Li - Fraumeni syndrome 17p tumor suppressor (blocks G1 to S phase progression)
p53 gene
skeletal muscle malignant tumor
TRAP
arsenic target

17. AL
bone malignant tumor
primary amyloidosis
paraneoplastic effects of thymoma - small cell lung carcinoma
Primary tumors that met to brain

18. Leiomyosarcoma
smooth muscle malignant tumor
c - kit gene
alpha - fetoprotein
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)

19. Squamous cell carcinoma of the esophagus
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)
DCC gene
benign epithelial tumor
ras gene

20. Retinoblastoma - osteosarcoma 13q tumor suppressor (blocks G1 to S phase progression)
WT1 gene
DPC gene
Rb gene
Second - leading cause of death in the US

21. Blood (leukemia)
Neoplasm associated with actinic keratosis
Alkylating agents target
breast cancer incidence/mortality
Autoimmune (Hashimoto's - myasthenia gravis)

22. Prostate (blastic) - thyroid - testes - breast (lytic and blastic) - lung (lytic) - kidney (breast and prostate are most common)
Leading cause of death in the US
Primary tumors that met to bone
NF1 gene
ulcerative colitis

23. Colon>stomach>pancreas>breast>lung (liver and lung are the most common places for mets)
Primary tumors that met to liver
Rb gene
cirrosis (alcohol - hepB or C)
primary amyloidosis

24. Tumor marker: thyroid medullary carcinoma
calcitonin
Colon and rectal cancer incidence
Necrosis
Bombesin

25. Leiomyoma
Where you see Psammoma bodies
erb - B2 gene
iron poisoning
smooth muscle benign tumor

26. ACTH or ACTH- like peptide
immunodeficiency states
paraneoplastic effects of small cell lung carcinoma
Free radical eliminators
paraneoplastic effects of renal cell carcinoma - hemangioblastoma

27. GIST cytokine receptor (oncogene)
c - kit gene
acanthosis nigricans (hyperpig and epidermal thickening)
benign >1 cell type tumor
Necrosis

28. Aggressive malignant lymphomas (non - Hodgkin's) and Kaposi's sarcoma
malignant >1 cell type tumor
AIDS
bone malignant tumor
granulomatous disease

29. Breast cancer 13q tumor suppressor (DNA repair protein)
BRAC2 gene
c - kit gene
primary amyloidosis
Leukocyte extravasation: rolling

30. Solid tissues with single blood supply. Heart - kidney and spleen.
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.
CA-19-9
BRAC2 gene
Pale infarcts

31. Osteosarcoma
bone malignant tumor
Leukocyte extravasation: diapedesis
malignant epithelial tumor
Bombesin

32. Tumor marker: neuroblastoma - lung and gastric cancer
vinyl chloride target
calcitonin
Bombesin
L- myc gene

33. CML tyrosine kinase (oncogene)
dysplastic nevus
abl gene
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)
CCl4 target

34. Vascular: E and P- selectin Leukocyte: Sialyl Lewis
intrinsic apoptosis
Leukocyte extravasation: rolling
beta - hCG
aflatoxin target

35. Mature teratoma in men or malignant teratoma in M/F
malignant >1 cell type tumor
c - myc gene
Colon and rectal cancer incidence
Where you see Psammoma bodies

36. 32%/18% female
S-100
breast cancer incidence/mortality
BRCA1 gene
secondary amyloidosis (reactive systemic)

37. Tumor marker: (Normal in fetus). Hepatocellular carcinomas. Nonseminomatous germ cell tumors of the testis.
acanthosis nigricans (hyperpig and epidermal thickening)
alpha - fetoprotein
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)
ras gene

38. Sarcoma - papillary thyroid cancer
Necrosis
Primary tumors that met to liver
alpha - fetoprotein
radiation exposure

39. Colon cancer (Deleted in Colon Cancer) 18q tumor suppressor
DCC gene
blood cell malignant tumors
Irreversible - plasias
abl gene

40. Neurofibromatosis type 2 22q tumor suppressor (key type 2=22)
ulcerative colitis
NF2 gene
benign epithelial tumor
immunodeficiency states

41. Neurofibromatosis type 1 17q tumor suppressor
S-100
CCl4 target
L- myc gene
NF1 gene

42. Liver (centrilobular necrosis - fatty change)
Chronic inflammatory mediators
Leukocyte extravasation: diapedesis
benign epithelial tumor
CCl4 target

43. Lung tumor transcription factor (oncogene)
Primary tumors that met to brain
vinyl chloride target
BRAC2 gene
L- myc gene

44. Caused by peroxidation of membrane lipids. Causes acute gastric bleeding and chronic metabolic acidosis and scarring.
prostate cancer incidence/mortality
NF1 gene
iron poisoning
PSA

45. AA
BRCA1 gene
blood vessels malignant tumor
radiation exposure
secondary amyloidosis (reactive systemic)

46. Breast - ovarian and gastric carcinomas tyrosine kinase (oncogene)
Neoplasm associated with Down Syndrome
erb - B2 gene
aflatoxin target
Prostatic acid phosphatase

47. Membrane lipid peroxidation - protein modification and DNA breakage.
fat malignant tumor
Free radical cell damage
alpha - fetoprotein
smooth muscle benign tumor

48. Malignant lymphoma
immunodeficiency states
NF1 gene
Alk - phos
CA-125

49. Osteoma
S-100
bone benign tumor
Paget's bone disease
extrinsic apoptosis

50. Restoration of normal structure - granulation tissue (vascularized + fibrosis) - abscess (fibrosis + pus) - fistula or scarring (collagen).
paraneoplastic effects of thymoma - small cell lung carcinoma
CEA
Resolution of inflammation
AIDS