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First Aid Basics

Subjects : health-sciences, first-aid

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Leiomyoma
DCC gene
Neoplasm associated with xeroderma pigmentosum (albinism)
smooth muscle benign tumor
malignant >1 cell type tumor

2. Liver (centrilobular necrosis - fatty change)
AIDS
CCl4 target
Autoimmune (Hashimoto's - myasthenia gravis)
BRCA1 gene

3. Vascular: E and P- selectin Leukocyte: Sialyl Lewis
radiation exposure
Leukocyte extravasation: rolling
paraneoplastic effects of small cell lung carcinoma
Autoimmune (Hashimoto's - myasthenia gravis)

4. Hyperplasia - metaplasia - dysplasia
Colon and rectal cancer incidence
Reversible - plasias
immunodeficiency states
intrinsic apoptosis

5. Gastric adenocacinoma
S-100
p53 gene
bone benign tumor
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants

6. Female 13% Male 12%
aflatoxin target
Colon and rectal cancer incidence
malignant >1 cell type tumor
Where you see Psammoma bodies

7. Tumor marker: neuroblastoma - lung and gastric cancer
Bombesin
Primary tumors that met to brain
APC gene
bone benign tumor

8. AL
alpha - fetoprotein
primary amyloidosis
lung cancer incidence/mortality
Irreversible - plasias

9. Colon carcinoma GTPase (oncogene)
ras gene
CCl4 target
Rb gene
CA-125

10. ADH
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms
AIDS
fat benign tumor
dysplastic nevus

11. Sarcoma - papillary thyroid cancer
BRCA1 gene
smooth muscle benign tumor
iron poisoning
radiation exposure

12. Aggressive malignant lymphomas (non - Hodgkin's) and Kaposi's sarcoma
Reversible - plasias
asbestos target
beta - hCG
AIDS

13. GIST cytokine receptor (oncogene)
bone malignant tumor
Leukocyte extravasation: migration
c - kit gene
paraneoplastic effects of small cell lung carcinoma

14. Hepatocellular carcinoma
cirrosis (alcohol - hepB or C)
DCC gene
Reversible - plasias
abl gene

15. Skin (SqCC) - liver (angiosarcoma)
arsenic target
Paget's bone disease
bone benign tumor
Alk - phos

16. Lipoma
ret gene
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
arsenic target
fat benign tumor

17. Malignant lymphoma
immunodeficiency states
iron poisoning
malignant mesenchyme tumor (general)
nitrosamines (smoked foods) target

18. Neutrophils (eos in the gut) - plus other granular leukocytes and antibodies.
c - kit gene
Reversible - plasias
Where you see Psammoma bodies
Acute inflammatory mediators

19. Lymphoma

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20. Ligand - receptor interactions. Release of perforin and granzyme B.
malignant >1 cell type tumor
Acute inflammatory mediators
extrinsic apoptosis
ret gene

21. Tumor marker: Hydatifiform moles - choriocarcinomas - gestational trophoblastic tumors.
ret gene
beta - hCG
WT1 gene
Neoplasm associated with Down Syndrome

22. Leiomyosarcoma
Leukocyte extravasation: migration
smooth muscle malignant tumor
DPC gene
CA-19-9

23. Liposarcoma
benign epithelial tumor
Alkylating agents target
prostate cancer incidence/mortality
fat malignant tumor

24. Solid tissues with single blood supply. Heart - kidney and spleen.
primary amyloidosis
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
Paget's bone disease
Pale infarcts

25. Retinoblastoma - osteosarcoma 13q tumor suppressor (blocks G1 to S phase progression)
Rb gene
calcitonin
aflatoxin target
granulomatous disease

26. Malignant melanoma
dysplastic nevus
NF1 gene
beta - hCG
lung cancer incidence/mortality

27. Tumor marker: prostate carcinoma marker.
Paget's bone disease
Prostatic acid phosphatase
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)
aflatoxin target

28. Breast cancer 13q tumor suppressor (DNA repair protein)
BRAC2 gene
paraneoplastic effects of thymoma - small cell lung carcinoma
Red (hemorrhagic) infarcts
malignant epithelial tumor

29. Squamous cell carcinoma of the esophagus
Autoimmune (Hashimoto's - myasthenia gravis)
S-100
Red (hemorrhagic) infarcts
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)

30. PECAM-1
causes of decreased ESR
DPC gene
BRAC2 gene
Leukocyte extravasation: diapedesis

31. Vascular: ICAM-1 Leukocyte: LFA-1 (integrin)
Leukocyte extravasation: tight binding
paraneoplastic effects of leukemias and lymphomas
malignant epithelial tumor
DPC gene

32. Tumor marker: melanoma - neural tumors - astrocytomas
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)
nitrosamines (smoked foods) target
S-100
bone benign tumor

33. Lung (mesothelioma and bronchogenic carcinoma)
ras gene
Barrett's esophagus (chronic GI reflux)
asbestos target
Resolution of inflammation

34. Visceral malignancy (stomach - lung - breast - uterus)
ret gene
aflatoxin target
benign >1 cell type tumor
acanthosis nigricans (hyperpig and epidermal thickening)

35. Colorectal cancer (assoc with FAP) 5q tumor suppressor
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.
APC gene
CA-19-9
dysplastic nevus

36. Lung tumor transcription factor (oncogene)
L- myc gene
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants
extrinsic apoptosis
CA-125

37. Astrocytoma - angiomyolipoma - cardiac rhabdomyoma
malignant epithelial tumor
fat malignant tumor
arsenic target
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)

38. Liver (hepatocellular carcinoma)
Pale infarcts
blood cell malignant tumors
aflatoxin target
ulcerative colitis

39. Osteoma
Alkylating agents target
c - kit gene
bone benign tumor
lung cancer incidence/mortality

40. Colon cancer (Deleted in Colon Cancer) 18q tumor suppressor
DPC gene
bcl -2 gene
Neoplasm associated with Down Syndrome
DCC gene

41. Cancer
causes of increased ESR
Second - leading cause of death in the US
ret gene
vinyl chloride target

42. Follicular and undifferentiated lymphomas anti - apoptotic molecule (oncogene)
Leading cause of death in the US
bcl -2 gene
WT1 gene
radiation exposure

43. Tumor marker: tartrate - resistant acid phosphatase. Hairy cell leukemia (B- cell neoplasm)
Neoplasm associated with actinic keratosis
causes of decreased ESR
TRAP
Resolution of inflammation

44. PTH- related peptide - TGF- beta - TNF - IL-1
cigarette smoke target
smooth muscle malignant tumor
CA-19-9
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.

45. Hyperuricemia (excess NA turnover)
Chronic inflammatory mediators
paraneoplastic effects of leukemias and lymphomas
intrinsic apoptosis
acanthosis nigricans (hyperpig and epidermal thickening)

46. Osteosarcoma
skeletal muscle benign tumor
bone malignant tumor
p16 gene
vinyl chloride target

47. Prostate (blastic) - thyroid - testes - breast (lytic and blastic) - lung (lytic) - kidney (breast and prostate are most common)
Resolution of inflammation
Primary tumors that met to bone
dysplastic nevus
abl gene

48. Antibodies to presynaptic Ca2+ channels at NM junction
breast cancer incidence/mortality
paraneoplastic effects of thymoma - small cell lung carcinoma
Acute inflammatory mediators
cirrosis (alcohol - hepB or C)

49. Bacterial products (CLIK):C5a - LTB4 - IL-8 - Kallikrein
Leukocyte extravasation: migration
p53 gene
Neoplasm associated with xeroderma pigmentosum (albinism)
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants

50. Tumor marker: Screen for prostate carcinoma. Can also be elevated in BPH and prostatitis.
APC gene
Red (hemorrhagic) infarcts
PSA
p53 gene

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First Aid Basics

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