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First Aid Basics

Subjects : health-sciences, first-aid

Instructions:

Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can study here.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Visceral malignancy (stomach - lung - breast - uterus)
iron poisoning
CCl4 target
asbestos target
acanthosis nigricans (hyperpig and epidermal thickening)

2. Tumor marker: ovarian - malignant epithelial tumors.
causes of decreased ESR
CA-125
Acute inflammatory mediators
Second - leading cause of death in the US

3. Colorectal cancer (assoc with FAP) 5q tumor suppressor
primary amyloidosis
APC gene
paraneoplastic effects of leukemias and lymphomas
iron poisoning

4. MEN type II and III tyrosine kinase (oncogene)
Alk - phos
ret gene
Resolution of inflammation
malignant mesenchyme tumor (general)

5. Larynx (SqCC) - lung (SqCC and SCC) - kidney (renal cell carcinoma) - bladder (transitional cell carcinoma)
ras gene
cigarette smoke target
Pale infarcts
lung cancer incidence/mortality

6. Burkitt's lymphoma transcription factor (oncogene)
Leukocyte extravasation: migration
Leukocyte extravasation: rolling
smooth muscle benign tumor
c - myc gene

7. Skin (SqCC) - liver (angiosarcoma)
Alk - phos
arsenic target
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)
malignant mesenchyme tumor (general)

8. Retinoblastoma - osteosarcoma 13q tumor suppressor (blocks G1 to S phase progression)
c - kit gene
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)
Rb gene
Primary tumors that met to liver

9. Tumor marker: prostate carcinoma marker.
paraneoplastic effects of leukemias and lymphomas
Prostatic acid phosphatase
erb - B2 gene
Free radical cell damage

10. Breast - ovarian and gastric carcinomas tyrosine kinase (oncogene)
benign epithelial tumor
abl gene
erb - B2 gene
Barrett's esophagus (chronic GI reflux)

11. Colonic adenocarcinoma
asbestos target
bone malignant tumor
ulcerative colitis
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)

12. Papillary (thyroid) - Serous (ovary) - Meningioma - Mesothelioma
malignant epithelial tumor
Where you see Psammoma bodies
Second - leading cause of death in the US
c - myc gene

13. Neurofibromatosis type 1 17q tumor suppressor
Autoimmune (Hashimoto's - myasthenia gravis)
blood vessels malignant tumor
cirrosis (alcohol - hepB or C)
NF1 gene

14. Sarcoma
smooth muscle benign tumor
malignant mesenchyme tumor (general)
Necrosis
Neoplasm associated with actinic keratosis

15. Heart disease
Free radical eliminators
p53 gene
Leading cause of death in the US
Red (hemorrhagic) infarcts

16. Hyperuricemia (excess NA turnover)
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.
blood vessels benign tumor
bcl -2 gene
paraneoplastic effects of leukemias and lymphomas

17. Neutrophils (eos in the gut) - plus other granular leukocytes and antibodies.
DPC gene
Acute inflammatory mediators
beta - hCG
intrinsic apoptosis

18. Tumor marker: Screen for prostate carcinoma. Can also be elevated in BPH and prostatitis.
PSA
causes of decreased ESR
Free radical cell damage
NF1 gene

19. Leiomyoma
smooth muscle benign tumor
intrinsic apoptosis
Chronic inflammatory mediators
Neoplasm associated with actinic keratosis

20. Esophagus - stomach
Primary tumors that met to bone
NF1 gene
nitrosamines (smoked foods) target
iron poisoning

21. Hyperplasia - metaplasia - dysplasia
Irreversible - plasias
bone benign tumor
Reversible - plasias
Free radical eliminators

22. Malignant melanoma
Free radical eliminators
N- myc gene
dysplastic nevus
granulomatous disease

23. Lipoma
WT1 gene
fat benign tumor
extrinsic apoptosis
Where you see Psammoma bodies

24. During embryogenesis - hormone induction and atrophy. Increased mitochondrial permeability and cytochrome c release. Increase Bax (pro - apoptotic) - decreased Bcl -2 (anti - apopotic).
Autoimmune (Hashimoto's - myasthenia gravis)
N- myc gene
intrinsic apoptosis
paraneoplastic effects of thymoma - small cell lung carcinoma

25. Osteoma
bone benign tumor
Free radical eliminators
L- myc gene
paraneoplastic effects of renal cell carcinoma - hemangioblastoma

26. PECAM-1
Barrett's esophagus (chronic GI reflux)
Rb gene
DPC gene
Leukocyte extravasation: diapedesis

27. Neuroblastoma transcription factor (oncogene)
Red (hemorrhagic) infarcts
N- myc gene
Primary tumors that met to bone
WT1 gene

28. Tumor marker: melanoma - neural tumors - astrocytomas
Irreversible - plasias
blood vessels benign tumor
S-100
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)

29. Ligand - receptor interactions. Release of perforin and granzyme B.
extrinsic apoptosis
S-100
causes of decreased ESR
NF2 gene

30. Neurofibromatosis type 2 22q tumor suppressor (key type 2=22)
Free radical cell damage
Second - leading cause of death in the US
abl gene
NF2 gene

31. Anaplasia - neoplasia - desmoplasia (fibrous tissue formation in response to neoplasm)
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
malignant mesenchyme tumor (general)
causes of increased ESR
Irreversible - plasias

32. TB - fungal infections - syphilis - leprosy - cat scratch fever - sarcoid - Crohn's - Berylliosis.
skeletal muscle benign tumor
Primary tumors that met to liver
granulomatous disease
Necrosis

33. Female 13%/23% and rising Male 16%/33% (mortality has plateaued)
lung cancer incidence/mortality
bone malignant tumor
Primary tumors that met to brain
malignant mesenchyme tumor (general)

34. Liver (hepatocellular carcinoma)
aflatoxin target
malignant >1 cell type tumor
blood vessels benign tumor
benign epithelial tumor

35. Cancer
cirrosis (alcohol - hepB or C)
CEA
Second - leading cause of death in the US
paraneoplastic effects of leukemias and lymphomas

36. Membrane lipid peroxidation - protein modification and DNA breakage.
Free radical cell damage
Rb gene
lung cancer incidence/mortality
Paget's bone disease

37. Infections - inflammation - cancer - pregnancy - SLE
Primary tumors that met to liver
blood cell malignant tumors
causes of increased ESR
Neoplasm associated with xeroderma pigmentosum (albinism)

38. Breast cancer 13q tumor suppressor (DNA repair protein)
Reversible - plasias
granulomatous disease
BRAC2 gene
Irreversible - plasias

39. Solid tissues with single blood supply. Heart - kidney and spleen.
Leukocyte extravasation: migration
Pale infarcts
Reversible - plasias
Rb gene

40. Mature teratoma in women
Alkylating agents target
cigarette smoke target
malignant >1 cell type tumor
benign >1 cell type tumor

41. Rhabdomyosarcoma
skeletal muscle malignant tumor
immunodeficiency states
intrinsic apoptosis
L- myc gene

42. Esophageal adenocarcinoma

43. Erythropoietin
erb - B2 gene
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
breast cancer incidence/mortality
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms

44. Lung - breast - skin (melanoma) - kidney (renal cell carcinoma) - GI.50% brain tumors are from mets
beta - hCG
benign epithelial tumor
Primary tumors that met to brain
nitrosamines (smoked foods) target

45. Leukemia - lymphoma
prostate cancer incidence/mortality
DPC gene
blood vessels benign tumor
blood cell malignant tumors

46. Caused by peroxidation of membrane lipids. Causes acute gastric bleeding and chronic metabolic acidosis and scarring.
iron poisoning
Colon and rectal cancer incidence
skeletal muscle benign tumor
extrinsic apoptosis

47. Colon>stomach>pancreas>breast>lung (liver and lung are the most common places for mets)
Primary tumors that met to liver
cigarette smoke target
Neoplasm associated with xeroderma pigmentosum (albinism)
Leukocyte extravasation: rolling

48. Adenocarcinoma - papillary carcinoma
malignant epithelial tumor
DPC gene
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)
Alk - phos

49. Most human cancers - specifically Li - Fraumeni syndrome 17p tumor suppressor (blocks G1 to S phase progression)
beta - hCG
p53 gene
smooth muscle benign tumor
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)

50. Vascular: ICAM-1 Leukocyte: LFA-1 (integrin)
Reversible - plasias
Leukocyte extravasation: tight binding
benign >1 cell type tumor
Napthalene (aniline) dyes target