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Test your basic knowledge |
First Aid Basics
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Most human cancers - specifically Li - Fraumeni syndrome 17p tumor suppressor (blocks G1 to S phase progression)
p53 gene
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
p16 gene
intrinsic apoptosis
2. Pancreatic cancer (Deleted in Pancreatic Cancer) 18q tumor suppressor
bone benign tumor
CEA
Red (hemorrhagic) infarcts
DPC gene
3. Hyperuricemia (excess NA turnover)
blood vessels malignant tumor
Necrosis
Irreversible - plasias
paraneoplastic effects of leukemias and lymphomas
4. Tumor marker: Screen for prostate carcinoma. Can also be elevated in BPH and prostatitis.
primary amyloidosis
PSA
blood vessels malignant tumor
Necrosis
5. Tumor marker: ovarian - malignant epithelial tumors.
BRCA1 gene
benign >1 cell type tumor
CA-125
bcl -2 gene
6. Burkitt's lymphoma transcription factor (oncogene)
c - myc gene
WT1 gene
blood cell malignant tumors
CCl4 target
7. Sarcoma
iron poisoning
malignant mesenchyme tumor (general)
PSA
acanthosis nigricans (hyperpig and epidermal thickening)
8. Colon>stomach>pancreas>breast>lung (liver and lung are the most common places for mets)
Primary tumors that met to liver
Chronic inflammatory mediators
Second - leading cause of death in the US
iron poisoning
9. AA
fat malignant tumor
secondary amyloidosis (reactive systemic)
CA-125
Pale infarcts
10. Larynx (SqCC) - lung (SqCC and SCC) - kidney (renal cell carcinoma) - bladder (transitional cell carcinoma)
causes of increased ESR
cigarette smoke target
malignant mesenchyme tumor (general)
benign >1 cell type tumor
11. Esophageal adenocarcinoma
12. Membrane lipid peroxidation - protein modification and DNA breakage.
radiation exposure
Free radical cell damage
Napthalene (aniline) dyes target
Reversible - plasias
13. Neurofibromatosis type 2 22q tumor suppressor (key type 2=22)
NF2 gene
alpha - fetoprotein
ret gene
Reversible - plasias
14. Heart disease
N- myc gene
Paget's bone disease
aflatoxin target
Leading cause of death in the US
15. Vascular: ICAM-1 Leukocyte: LFA-1 (integrin)
Leading cause of death in the US
Resolution of inflammation
Free radical cell damage
Leukocyte extravasation: tight binding
16. Gastric adenocacinoma
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)
CEA
ras gene
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants
17. PECAM-1
Primary tumors that met to brain
Leukocyte extravasation: diapedesis
aflatoxin target
p16 gene
18. GIST cytokine receptor (oncogene)
c - kit gene
c - myc gene
iron poisoning
cirrosis (alcohol - hepB or C)
19. Restoration of normal structure - granulation tissue (vascularized + fibrosis) - abscess (fibrosis + pus) - fistula or scarring (collagen).
Resolution of inflammation
prostate cancer incidence/mortality
dysplastic nevus
immunodeficiency states
20. TB - fungal infections - syphilis - leprosy - cat scratch fever - sarcoid - Crohn's - Berylliosis.
fat malignant tumor
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms
granulomatous disease
Leading cause of death in the US
21. Caused by peroxidation of membrane lipids. Causes acute gastric bleeding and chronic metabolic acidosis and scarring.
iron poisoning
Primary tumors that met to bone
secondary amyloidosis (reactive systemic)
c - myc gene
22. Antibodies to presynaptic Ca2+ channels at NM junction
NF2 gene
paraneoplastic effects of thymoma - small cell lung carcinoma
Prostatic acid phosphatase
smooth muscle malignant tumor
23. Liver (centrilobular necrosis - fatty change)
CCl4 target
APC gene
Free radical eliminators
aflatoxin target
24. Osteosarcoma
Where you see Psammoma bodies
Prostatic acid phosphatase
CEA
bone malignant tumor
25. ACTH or ACTH- like peptide
Leukocyte extravasation: rolling
paraneoplastic effects of small cell lung carcinoma
CA-19-9
Irreversible - plasias
26. Neuroblastoma transcription factor (oncogene)
N- myc gene
extrinsic apoptosis
p16 gene
Bombesin
27. Prostate (blastic) - thyroid - testes - breast (lytic and blastic) - lung (lytic) - kidney (breast and prostate are most common)
Primary tumors that met to bone
Irreversible - plasias
intrinsic apoptosis
Leukocyte extravasation: diapedesis
28. Astrocytoma - angiomyolipoma - cardiac rhabdomyoma
p53 gene
Necrosis
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)
Leukocyte extravasation: rolling
29. Erythropoietin
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
Leukocyte extravasation: migration
NF2 gene
bone benign tumor
30. Rhabdomyoma
skeletal muscle benign tumor
Colon and rectal cancer incidence
Prostatic acid phosphatase
arsenic target
31. Tumor marker: melanoma - neural tumors - astrocytomas
S-100
Leukocyte extravasation: rolling
CA-19-9
WT1 gene
32. Secondary osteosarcoma and fibrosarcoma
33. Tumor marker: Hydatifiform moles - choriocarcinomas - gestational trophoblastic tumors.
arsenic target
beta - hCG
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms
Primary tumors that met to liver
34. Bacterial products (CLIK):C5a - LTB4 - IL-8 - Kallikrein
Leukocyte extravasation: migration
N- myc gene
Leukocyte extravasation: diapedesis
Primary tumors that met to brain
35. AL
primary amyloidosis
arsenic target
Rb gene
secondary amyloidosis (reactive systemic)
36. Breast and ovarian cancer 17q tumor suppressor (DNA repair protein)
Napthalene (aniline) dyes target
BRCA1 gene
paraneoplastic effects of small cell lung carcinoma
malignant mesenchyme tumor (general)
37. Mature teratoma in women
BRAC2 gene
L- myc gene
fat malignant tumor
benign >1 cell type tumor
38. 32%/13% male
NF1 gene
prostate cancer incidence/mortality
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)
cirrosis (alcohol - hepB or C)
39. Tumor marker: mets to bone - obstructive biliary disease - Paget's
BRCA1 gene
c - kit gene
Alk - phos
CCl4 target
40. Lung tumor transcription factor (oncogene)
L- myc gene
BRAC2 gene
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
Acute inflammatory mediators
41. Tumor marker: prostate carcinoma marker.
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.
ras gene
CA-19-9
Prostatic acid phosphatase
42. Liver (hepatocellular carcinoma)
aflatoxin target
erb - B2 gene
ras gene
CCl4 target
43. Lung - liver - intestine or following reperfusion.
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms
Red (hemorrhagic) infarcts
Reversible - plasias
Free radical eliminators
44. Skin (SqCC) - liver (angiosarcoma)
aflatoxin target
Alkylating agents target
Free radical eliminators
arsenic target
45. Tumor marker: thyroid medullary carcinoma
calcitonin
erb - B2 gene
bone malignant tumor
CCl4 target
46. Colorectal cancer (assoc with FAP) 5q tumor suppressor
p53 gene
CCl4 target
paraneoplastic effects of thymoma - small cell lung carcinoma
APC gene
47. Macrophages and lymphocytes. Persistant destruction and repair.
causes of increased ESR
ras gene
radiation exposure
Chronic inflammatory mediators
48. Angiosarcoma
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.
blood vessels malignant tumor
asbestos target
bcl -2 gene
49. PTH- related peptide - TGF- beta - TNF - IL-1
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.
extrinsic apoptosis
NF1 gene
dysplastic nevus
50. Osteoma
Necrosis
CA-125
CA-19-9
bone benign tumor