First Aid Basics

Instructions:

• Answer 50 questions in 15 minutes.
• If you are not ready to take this test, you can study here.
• Match each statement with the correct term.
• Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Cancer
Second - leading cause of death in the US
PSA
cirrosis (alcohol - hepB or C)
Free radical eliminators


2. Tumor marker: (Normal in fetus). Hepatocellular carcinomas. Nonseminomatous germ cell tumors of the testis.
NF2 gene
Leukocyte extravasation: migration
alpha - fetoprotein
skeletal muscle malignant tumor


3. Melanoma - basal cell carcinoma - and especially squamous cell carcinomas of the skin.
Paget's bone disease
blood vessels malignant tumor
Neoplasm associated with xeroderma pigmentosum (albinism)
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)


4. Wilms' tumor 11p tumor suppressor
Prostatic acid phosphatase
Primary tumors that met to liver
WT1 gene
fat malignant tumor


5. 32%/18% female
breast cancer incidence/mortality
ras gene
L- myc gene
vinyl chloride target


6. Tumor marker: carcinoembryonic Ag Very nonspecific
Rb gene
Free radical eliminators
smooth muscle malignant tumor
CEA


7. Sarcoma
Bombesin
AIDS
malignant mesenchyme tumor (general)
NF1 gene


8. Leiomyoma
Reversible - plasias
calcitonin
smooth muscle benign tumor
iron poisoning


9. Squamous cell carcinoma of the esophagus
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)
causes of increased ESR
iron poisoning
Barrett's esophagus (chronic GI reflux)


10. MEN type II and III tyrosine kinase (oncogene)
causes of decreased ESR
Bombesin
Second - leading cause of death in the US
ret gene


11. ADH
prostate cancer incidence/mortality
blood cell malignant tumors
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms
Acute inflammatory mediators


12. All - AML
extrinsic apoptosis
DPC gene
Neoplasm associated with Down Syndrome
skeletal muscle benign tumor


13. Tumor marker: thyroid medullary carcinoma
CEA
calcitonin
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.
Primary tumors that met to bone


14. Squamous cell carcinoma of skin
prostate cancer incidence/mortality
BRAC2 gene
malignant mesenchyme tumor (general)
Neoplasm associated with actinic keratosis


15. Papillary (thyroid) - Serous (ovary) - Meningioma - Mesothelioma
extrinsic apoptosis
Where you see Psammoma bodies
CEA
Alk - phos


16. Lipoma
Acute inflammatory mediators
Leukocyte extravasation: rolling
fat benign tumor
c - kit gene


17. Sarcoma - papillary thyroid cancer
aflatoxin target
Paget's bone disease
radiation exposure
Primary tumors that met to bone


18. Mature teratoma in men or malignant teratoma in M/F
Barrett's esophagus (chronic GI reflux)
malignant >1 cell type tumor
Necrosis
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.


19. Colon carcinoma GTPase (oncogene)
calcitonin
Leading cause of death in the US
Necrosis
ras gene


20. ACTH or ACTH- like peptide
paraneoplastic effects of small cell lung carcinoma
Autoimmune (Hashimoto's - myasthenia gravis)
Reversible - plasias
acanthosis nigricans (hyperpig and epidermal thickening)


21. Liver (hepatocellular carcinoma)
c - myc gene
bone benign tumor
dysplastic nevus
aflatoxin target


22. Rhabdomyosarcoma
skeletal muscle malignant tumor
immunodeficiency states
primary amyloidosis
cirrosis (alcohol - hepB or C)


23. Follicular and undifferentiated lymphomas anti - apoptotic molecule (oncogene)
Reversible - plasias
fat malignant tumor
bcl -2 gene
CCl4 target


24. Infections - inflammation - cancer - pregnancy - SLE
Leading cause of death in the US
NF2 gene
causes of increased ESR
prostate cancer incidence/mortality


25. Mature teratoma in women
Prostatic acid phosphatase
Paget's bone disease
benign >1 cell type tumor
Necrosis


26. During embryogenesis - hormone induction and atrophy. Increased mitochondrial permeability and cytochrome c release. Increase Bax (pro - apoptotic) - decreased Bcl -2 (anti - apopotic).
intrinsic apoptosis
N- myc gene
CEA
alpha - fetoprotein


27. Erythropoietin
TRAP
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
Primary tumors that met to brain
Napthalene (aniline) dyes target


28. Burkitt's lymphoma transcription factor (oncogene)
c - myc gene
bone malignant tumor
Colon and rectal cancer incidence
Paget's bone disease


29. Vascular: ICAM-1 Leukocyte: LFA-1 (integrin)
paraneoplastic effects of small cell lung carcinoma
immunodeficiency states
Leukocyte extravasation: tight binding
S-100


30. Neuroblastoma transcription factor (oncogene)
N- myc gene
paraneoplastic effects of leukemias and lymphomas
prostate cancer incidence/mortality
bcl -2 gene


31. Tumor marker: neuroblastoma - lung and gastric cancer
N- myc gene
L- myc gene
Bombesin
dysplastic nevus


32. Osteoma
NF1 gene
bone benign tumor
iron poisoning
BRCA1 gene


33. Lung - liver - intestine or following reperfusion.
c - kit gene
Red (hemorrhagic) infarcts
Autoimmune (Hashimoto's - myasthenia gravis)
Primary tumors that met to bone


34. Blood (leukemia)
causes of increased ESR
Alkylating agents target
aflatoxin target
fat benign tumor


35. Female 13%/23% and rising Male 16%/33% (mortality has plateaued)
Pale infarcts
Autoimmune (Hashimoto's - myasthenia gravis)
lung cancer incidence/mortality
dysplastic nevus


36. Adenoma - papilloma
benign >1 cell type tumor
malignant mesenchyme tumor (general)
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
benign epithelial tumor


37. Liposarcoma
Irreversible - plasias
malignant mesenchyme tumor (general)
fat malignant tumor
PSA


38. CML tyrosine kinase (oncogene)
smooth muscle benign tumor
abl gene
bone malignant tumor
asbestos target


39. Breast and ovarian cancer 17q tumor suppressor (DNA repair protein)
breast cancer incidence/mortality
BRCA1 gene
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.
c - myc gene


40. Breast - ovarian and gastric carcinomas tyrosine kinase (oncogene)
erb - B2 gene
paraneoplastic effects of small cell lung carcinoma
skeletal muscle malignant tumor
ras gene


41. Colorectal cancer (assoc with FAP) 5q tumor suppressor
APC gene
DPC gene
Leukocyte extravasation: tight binding
Neoplasm associated with actinic keratosis


42. Tumor marker: prostate carcinoma marker.
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)
TRAP
p53 gene
Prostatic acid phosphatase


43. TB - fungal infections - syphilis - leprosy - cat scratch fever - sarcoid - Crohn's - Berylliosis.
AIDS
granulomatous disease
Chronic inflammatory mediators
BRAC2 gene


44. Bladder (transitional cell carcinoma)
malignant >1 cell type tumor
CCl4 target
iron poisoning
Napthalene (aniline) dyes target


45. Aggressive malignant lymphomas (non - Hodgkin's) and Kaposi's sarcoma
AIDS
Leukocyte extravasation: rolling
secondary amyloidosis (reactive systemic)
Leading cause of death in the US


46. Heart disease
Leading cause of death in the US
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.
Free radical eliminators
Primary tumors that met to brain


47. Female 13% Male 12%
Alk - phos
Primary tumors that met to brain
Pale infarcts
Colon and rectal cancer incidence


48. Antibodies to presynaptic Ca2+ channels at NM junction
paraneoplastic effects of thymoma - small cell lung carcinoma
nitrosamines (smoked foods) target
Barrett's esophagus (chronic GI reflux)
Neoplasm associated with actinic keratosis


49. Lung - breast - skin (melanoma) - kidney (renal cell carcinoma) - GI.50% brain tumors are from mets
Primary tumors that met to brain
Paget's bone disease
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)
AIDS


50. Tumor marker: mets to bone - obstructive biliary disease - Paget's
Alk - phos
TRAP
arsenic target
Leukocyte extravasation: migration