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First Aid Basics

Subjects : health-sciences, first-aid

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Leiomyosarcoma
Prostatic acid phosphatase
smooth muscle malignant tumor
paraneoplastic effects of thymoma - small cell lung carcinoma
blood vessels benign tumor

2. Tumor marker: Hydatifiform moles - choriocarcinomas - gestational trophoblastic tumors.
paraneoplastic effects of thymoma - small cell lung carcinoma
malignant mesenchyme tumor (general)
beta - hCG
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)

3. Neuroblastoma transcription factor (oncogene)
Leukocyte extravasation: rolling
bone malignant tumor
N- myc gene
intrinsic apoptosis

4. Sarcoma - papillary thyroid cancer
Primary tumors that met to liver
radiation exposure
bcl -2 gene
p53 gene

5. Aggressive malignant lymphomas (non - Hodgkin's) and Kaposi's sarcoma
Reversible - plasias
smooth muscle benign tumor
primary amyloidosis
AIDS

6. PECAM-1
Leukocyte extravasation: diapedesis
Bombesin
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants
blood cell malignant tumors

7. TB - fungal infections - syphilis - leprosy - cat scratch fever - sarcoid - Crohn's - Berylliosis.
skeletal muscle benign tumor
Primary tumors that met to brain
granulomatous disease
p53 gene

8. Solid tissues with single blood supply. Heart - kidney and spleen.
NF1 gene
intrinsic apoptosis
blood cell malignant tumors
Pale infarcts

9. Astrocytoma - angiomyolipoma - cardiac rhabdomyoma
smooth muscle malignant tumor
blood vessels malignant tumor
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)
causes of decreased ESR

10. Membrane lipid peroxidation - protein modification and DNA breakage.
Free radical cell damage
Free radical eliminators
Pale infarcts
Leukocyte extravasation: rolling

11. Heart disease
Leading cause of death in the US
p16 gene
NF2 gene
smooth muscle benign tumor

12. Papillary (thyroid) - Serous (ovary) - Meningioma - Mesothelioma
Where you see Psammoma bodies
Napthalene (aniline) dyes target
acanthosis nigricans (hyperpig and epidermal thickening)
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.

13. Rhabdomyoma
Leukocyte extravasation: tight binding
NF1 gene
skeletal muscle benign tumor
Second - leading cause of death in the US

14. All - AML
malignant epithelial tumor
vinyl chloride target
blood vessels malignant tumor
Neoplasm associated with Down Syndrome

15. ADH
Irreversible - plasias
Free radical cell damage
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms
PSA

16. Secondary osteosarcoma and fibrosarcoma

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17. Pancreatic cancer (Deleted in Pancreatic Cancer) 18q tumor suppressor
Acute inflammatory mediators
DPC gene
Barrett's esophagus (chronic GI reflux)
Alkylating agents target

18. Macrophages and lymphocytes. Persistant destruction and repair.
Chronic inflammatory mediators
c - myc gene
BRCA1 gene
malignant mesenchyme tumor (general)

19. Cancer
skeletal muscle malignant tumor
Leukocyte extravasation: rolling
N- myc gene
Second - leading cause of death in the US

20. GIST cytokine receptor (oncogene)
Chronic inflammatory mediators
c - kit gene
nitrosamines (smoked foods) target
N- myc gene

21. Malignant lymphoma
Free radical eliminators
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)
vinyl chloride target
immunodeficiency states

22. PTH- related peptide - TGF- beta - TNF - IL-1
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.
arsenic target
blood vessels malignant tumor
nitrosamines (smoked foods) target

23. Retinoblastoma - osteosarcoma 13q tumor suppressor (blocks G1 to S phase progression)
Alk - phos
skeletal muscle malignant tumor
Acute inflammatory mediators
Rb gene

24. Sickle cell (altered shape) - polycythemia (too many) - CHF (unknown)
CA-125
causes of decreased ESR
L- myc gene
CCl4 target

25. Liver (hepatocellular carcinoma)
bone benign tumor
Leukocyte extravasation: diapedesis
aflatoxin target
Where you see Psammoma bodies

26. Colorectal cancer (assoc with FAP) 5q tumor suppressor
APC gene
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms
Leading cause of death in the US
Acute inflammatory mediators

27. Wilms' tumor 11p tumor suppressor
CA-19-9
Irreversible - plasias
WT1 gene
paraneoplastic effects of renal cell carcinoma - hemangioblastoma

28. Anaplasia - neoplasia - desmoplasia (fibrous tissue formation in response to neoplasm)
primary amyloidosis
Irreversible - plasias
arsenic target
L- myc gene

29. Burkitt's lymphoma transcription factor (oncogene)
CA-19-9
NF1 gene
c - myc gene
Acute inflammatory mediators

30. Tumor marker: ovarian - malignant epithelial tumors.
Chronic inflammatory mediators
vinyl chloride target
CA-125
dysplastic nevus

31. Tumor marker: melanoma - neural tumors - astrocytomas
NF2 gene
S-100
Alk - phos
paraneoplastic effects of small cell lung carcinoma

32. Tumor marker: carcinoembryonic Ag Very nonspecific
intrinsic apoptosis
CEA
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
p16 gene

33. Tumor marker: thyroid medullary carcinoma
Barrett's esophagus (chronic GI reflux)
NF2 gene
calcitonin
cirrosis (alcohol - hepB or C)

34. During embryogenesis - hormone induction and atrophy. Increased mitochondrial permeability and cytochrome c release. Increase Bax (pro - apoptotic) - decreased Bcl -2 (anti - apopotic).
intrinsic apoptosis
blood vessels benign tumor
paraneoplastic effects of thymoma - small cell lung carcinoma
APC gene

35. AA
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants
causes of increased ESR
intrinsic apoptosis
secondary amyloidosis (reactive systemic)

36. Most human cancers - specifically Li - Fraumeni syndrome 17p tumor suppressor (blocks G1 to S phase progression)
secondary amyloidosis (reactive systemic)
APC gene
p53 gene
BRCA1 gene

37. Tumor marker: Screen for prostate carcinoma. Can also be elevated in BPH and prostatitis.
PSA
Leukocyte extravasation: migration
NF2 gene
paraneoplastic effects of leukemias and lymphomas

38. Larynx (SqCC) - lung (SqCC and SCC) - kidney (renal cell carcinoma) - bladder (transitional cell carcinoma)
intrinsic apoptosis
cigarette smoke target
Leukocyte extravasation: diapedesis
N- myc gene

39. Rhabdomyosarcoma
BRAC2 gene
Rb gene
skeletal muscle malignant tumor
c - kit gene

40. Erythropoietin
blood cell malignant tumors
AIDS
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
Reversible - plasias

41. Breast and ovarian cancer 17q tumor suppressor (DNA repair protein)
ret gene
Leukocyte extravasation: rolling
Leukocyte extravasation: tight binding
BRCA1 gene

42. Lipoma
fat benign tumor
ulcerative colitis
Neoplasm associated with actinic keratosis
immunodeficiency states

43. 32%/13% male
skeletal muscle benign tumor
blood vessels malignant tumor
prostate cancer incidence/mortality
primary amyloidosis

44. Hyperplasia - metaplasia - dysplasia
primary amyloidosis
Neoplasm associated with Down Syndrome
Reversible - plasias
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms

45. Prostate (blastic) - thyroid - testes - breast (lytic and blastic) - lung (lytic) - kidney (breast and prostate are most common)
Primary tumors that met to bone
Second - leading cause of death in the US
Free radical cell damage
Neoplasm associated with xeroderma pigmentosum (albinism)

46. Lung - liver - intestine or following reperfusion.
causes of increased ESR
Leukocyte extravasation: migration
secondary amyloidosis (reactive systemic)
Red (hemorrhagic) infarcts

47. Neurofibromatosis type 1 17q tumor suppressor
arsenic target
Reversible - plasias
NF1 gene
Paget's bone disease

48. Osteosarcoma
fat benign tumor
asbestos target
bone malignant tumor
Rb gene

49. Hepatocellular carcinoma
dysplastic nevus
cirrosis (alcohol - hepB or C)
NF2 gene
fat benign tumor

50. Gastric adenocacinoma
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants
intrinsic apoptosis
paraneoplastic effects of small cell lung carcinoma
blood cell malignant tumors

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First Aid Basics

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