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First Aid Basics

Subjects : health-sciences, first-aid

Instructions:

Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can study here.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Astrocytoma - angiomyolipoma - cardiac rhabdomyoma
BRCA1 gene
lung cancer incidence/mortality
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)

2. Lipoma
cigarette smoke target
arsenic target
fat benign tumor
ret gene

3. TB - fungal infections - syphilis - leprosy - cat scratch fever - sarcoid - Crohn's - Berylliosis.
granulomatous disease
Napthalene (aniline) dyes target
Rb gene
breast cancer incidence/mortality

4. Colon cancer (Deleted in Colon Cancer) 18q tumor suppressor
DCC gene
nitrosamines (smoked foods) target
Bombesin
Red (hemorrhagic) infarcts

5. Aggressive malignant lymphomas (non - Hodgkin's) and Kaposi's sarcoma
AIDS
immunodeficiency states
BRAC2 gene
cigarette smoke target

6. Neurofibromatosis type 1 17q tumor suppressor
Red (hemorrhagic) infarcts
NF1 gene
Colon and rectal cancer incidence
extrinsic apoptosis

7. Prostate (blastic) - thyroid - testes - breast (lytic and blastic) - lung (lytic) - kidney (breast and prostate are most common)
malignant mesenchyme tumor (general)
ras gene
calcitonin
Primary tumors that met to bone

8. Blood (leukemia)
TRAP
Prostatic acid phosphatase
blood vessels benign tumor
Alkylating agents target

9. Lung - breast - skin (melanoma) - kidney (renal cell carcinoma) - GI.50% brain tumors are from mets
malignant epithelial tumor
benign >1 cell type tumor
S-100
Primary tumors that met to brain

10. Rhabdomyoma
skeletal muscle benign tumor
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)
skeletal muscle malignant tumor
malignant >1 cell type tumor

11. AL
primary amyloidosis
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.
NF1 gene
TRAP

12. Tumor marker: mets to bone - obstructive biliary disease - Paget's
alpha - fetoprotein
bone malignant tumor
Alk - phos
Leukocyte extravasation: migration

13. Burkitt's lymphoma transcription factor (oncogene)
benign epithelial tumor
c - myc gene
Reversible - plasias
smooth muscle malignant tumor

14. Visceral malignancy (stomach - lung - breast - uterus)
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
bone benign tumor
extrinsic apoptosis
acanthosis nigricans (hyperpig and epidermal thickening)

15. Melanoma 9p tumor suppressor
Irreversible - plasias
p16 gene
lung cancer incidence/mortality
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants

16. Colorectal cancer (assoc with FAP) 5q tumor suppressor
APC gene
c - myc gene
smooth muscle malignant tumor
paraneoplastic effects of thymoma - small cell lung carcinoma

17. Melanoma - basal cell carcinoma - and especially squamous cell carcinomas of the skin.
secondary amyloidosis (reactive systemic)
acanthosis nigricans (hyperpig and epidermal thickening)
Neoplasm associated with xeroderma pigmentosum (albinism)
calcitonin

18. Vascular: ICAM-1 Leukocyte: LFA-1 (integrin)
Leukocyte extravasation: tight binding
Chronic inflammatory mediators
alpha - fetoprotein
BRCA1 gene

19. Erythropoietin
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
BRAC2 gene
blood cell malignant tumors
Red (hemorrhagic) infarcts

20. Colonic adenocarcinoma
primary amyloidosis
ulcerative colitis
Paget's bone disease
ret gene

21. Restoration of normal structure - granulation tissue (vascularized + fibrosis) - abscess (fibrosis + pus) - fistula or scarring (collagen).
DCC gene
Prostatic acid phosphatase
smooth muscle malignant tumor
Resolution of inflammation

22. Bladder (transitional cell carcinoma)
Leukocyte extravasation: tight binding
Napthalene (aniline) dyes target
NF1 gene
Leukocyte extravasation: diapedesis

23. Lung tumor transcription factor (oncogene)
L- myc gene
Leukocyte extravasation: migration
Chronic inflammatory mediators
Free radical cell damage

24. Angiosarcoma
skeletal muscle benign tumor
blood vessels malignant tumor
c - kit gene
Autoimmune (Hashimoto's - myasthenia gravis)

25. Adenoma - papilloma
TRAP
fat malignant tumor
benign epithelial tumor
paraneoplastic effects of renal cell carcinoma - hemangioblastoma

26. Leiomyoma
primary amyloidosis
causes of decreased ESR
smooth muscle benign tumor
Napthalene (aniline) dyes target

27. 32%/18% female
p16 gene
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)
breast cancer incidence/mortality
Leukocyte extravasation: rolling

28. Bacterial products (CLIK):C5a - LTB4 - IL-8 - Kallikrein
TRAP
APC gene
bcl -2 gene
Leukocyte extravasation: migration

29. Infections - inflammation - cancer - pregnancy - SLE
extrinsic apoptosis
causes of increased ESR
smooth muscle benign tumor
Napthalene (aniline) dyes target

30. Sickle cell (altered shape) - polycythemia (too many) - CHF (unknown)
causes of decreased ESR
NF2 gene
benign >1 cell type tumor
L- myc gene

31. Neutrophils (eos in the gut) - plus other granular leukocytes and antibodies.
Leukocyte extravasation: migration
Autoimmune (Hashimoto's - myasthenia gravis)
Acute inflammatory mediators
fat malignant tumor

32. Heart disease
Leukocyte extravasation: tight binding
Leading cause of death in the US
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)
fat malignant tumor

33. Wilms' tumor 11p tumor suppressor
benign epithelial tumor
WT1 gene
Neoplasm associated with xeroderma pigmentosum (albinism)
AIDS

34. Larynx (SqCC) - lung (SqCC and SCC) - kidney (renal cell carcinoma) - bladder (transitional cell carcinoma)
benign epithelial tumor
cigarette smoke target
p16 gene
fat malignant tumor

35. Tumor marker: Screen for prostate carcinoma. Can also be elevated in BPH and prostatitis.
PSA
Leading cause of death in the US
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants
Alkylating agents target

36. CML tyrosine kinase (oncogene)
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms
fat benign tumor
S-100
abl gene

37. PTH- related peptide - TGF- beta - TNF - IL-1
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.
paraneoplastic effects of small cell lung carcinoma
ret gene
fat benign tumor

38. Tumor marker: ovarian - malignant epithelial tumors.
prostate cancer incidence/mortality
CA-125
ret gene
DPC gene

39. Neurofibromatosis type 2 22q tumor suppressor (key type 2=22)
skeletal muscle malignant tumor
NF2 gene
Leukocyte extravasation: diapedesis
Alkylating agents target

40. Breast and ovarian cancer 17q tumor suppressor (DNA repair protein)
BRCA1 gene
WT1 gene
acanthosis nigricans (hyperpig and epidermal thickening)
blood cell malignant tumors

41. Tumor marker: Hydatifiform moles - choriocarcinomas - gestational trophoblastic tumors.
beta - hCG
Neoplasm associated with actinic keratosis
NF2 gene
malignant mesenchyme tumor (general)

42. Tumor marker: carcinoembryonic Ag Very nonspecific
causes of decreased ESR
p16 gene
benign epithelial tumor
CEA

43. During embryogenesis - hormone induction and atrophy. Increased mitochondrial permeability and cytochrome c release. Increase Bax (pro - apoptotic) - decreased Bcl -2 (anti - apopotic).
calcitonin
intrinsic apoptosis
PSA
Leukocyte extravasation: migration

44. Macrophages and lymphocytes. Persistant destruction and repair.
immunodeficiency states
Chronic inflammatory mediators
ras gene
paraneoplastic effects of small cell lung carcinoma

45. Osteoma
ras gene
calcitonin
radiation exposure
bone benign tumor

46. Adenocarcinoma - papillary carcinoma
beta - hCG
c - myc gene
dysplastic nevus
malignant epithelial tumor

47. Sarcoma
paraneoplastic effects of leukemias and lymphomas
Necrosis
malignant mesenchyme tumor (general)
PSA

48. Hyperplasia - metaplasia - dysplasia
Alkylating agents target
Colon and rectal cancer incidence
DPC gene
Reversible - plasias

49. Liver (angiosarcoma)
TRAP
vinyl chloride target
Reversible - plasias
prostate cancer incidence/mortality

50. Tumor marker: prostate carcinoma marker.
Leukocyte extravasation: rolling
Prostatic acid phosphatase
Reversible - plasias
ras gene