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First Aid Basics

Subjects : health-sciences, first-aid

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Visceral malignancy (stomach - lung - breast - uterus)
Pale infarcts
acanthosis nigricans (hyperpig and epidermal thickening)
Leukocyte extravasation: rolling
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms

2. Bladder (transitional cell carcinoma)
Napthalene (aniline) dyes target
skeletal muscle benign tumor
c - kit gene
breast cancer incidence/mortality

3. Neutrophils (eos in the gut) - plus other granular leukocytes and antibodies.
Acute inflammatory mediators
Napthalene (aniline) dyes target
fat malignant tumor
blood cell malignant tumors

4. All - AML
malignant mesenchyme tumor (general)
Acute inflammatory mediators
Bombesin
Neoplasm associated with Down Syndrome

5. Ligand - receptor interactions. Release of perforin and granzyme B.
ulcerative colitis
S-100
bone benign tumor
extrinsic apoptosis

6. Liver (angiosarcoma)
malignant mesenchyme tumor (general)
acanthosis nigricans (hyperpig and epidermal thickening)
vinyl chloride target
bone malignant tumor

7. Blood (leukemia)
NF1 gene
Alkylating agents target
Resolution of inflammation
Free radical eliminators

8. Colon carcinoma GTPase (oncogene)
Irreversible - plasias
ras gene
blood cell malignant tumors
DCC gene

9. Tumor marker: Screen for prostate carcinoma. Can also be elevated in BPH and prostatitis.
Barrett's esophagus (chronic GI reflux)
blood vessels benign tumor
PSA
Leukocyte extravasation: migration

10. Tumor marker: tartrate - resistant acid phosphatase. Hairy cell leukemia (B- cell neoplasm)
intrinsic apoptosis
skeletal muscle benign tumor
TRAP
BRAC2 gene

11. Leiomyoma
Leukocyte extravasation: rolling
smooth muscle benign tumor
paraneoplastic effects of leukemias and lymphomas
Primary tumors that met to bone

12. Retinoblastoma - osteosarcoma 13q tumor suppressor (blocks G1 to S phase progression)
Rb gene
Autoimmune (Hashimoto's - myasthenia gravis)
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms
DCC gene

13. Breast and ovarian cancer 17q tumor suppressor (DNA repair protein)
BRCA1 gene
smooth muscle benign tumor
APC gene
malignant mesenchyme tumor (general)

14. Malignant melanoma
dysplastic nevus
Paget's bone disease
breast cancer incidence/mortality
bone benign tumor

15. Cancer
Primary tumors that met to liver
radiation exposure
Second - leading cause of death in the US
ras gene

16. Melanoma 9p tumor suppressor
NF1 gene
DCC gene
paraneoplastic effects of small cell lung carcinoma
p16 gene

17. Vascular: ICAM-1 Leukocyte: LFA-1 (integrin)
c - myc gene
Leukocyte extravasation: tight binding
Free radical eliminators
N- myc gene

18. Liposarcoma
Alkylating agents target
CCl4 target
benign epithelial tumor
fat malignant tumor

19. Prostate (blastic) - thyroid - testes - breast (lytic and blastic) - lung (lytic) - kidney (breast and prostate are most common)
acanthosis nigricans (hyperpig and epidermal thickening)
breast cancer incidence/mortality
Irreversible - plasias
Primary tumors that met to bone

20. PECAM-1
erb - B2 gene
Alk - phos
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)
Leukocyte extravasation: diapedesis

21. Esophagus - stomach
Primary tumors that met to brain
fat malignant tumor
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants
nitrosamines (smoked foods) target

22. Colon cancer (Deleted in Colon Cancer) 18q tumor suppressor
dysplastic nevus
DCC gene
calcitonin
PSA

23. Esophageal adenocarcinoma

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24. Colon>stomach>pancreas>breast>lung (liver and lung are the most common places for mets)
Primary tumors that met to liver
PSA
malignant epithelial tumor
Free radical eliminators

25. Breast - ovarian and gastric carcinomas tyrosine kinase (oncogene)
erb - B2 gene
beta - hCG
malignant epithelial tumor
L- myc gene

26. Tumor marker: Hydatifiform moles - choriocarcinomas - gestational trophoblastic tumors.
Leukocyte extravasation: diapedesis
Primary tumors that met to bone
beta - hCG
blood cell malignant tumors

27. Caused by peroxidation of membrane lipids. Causes acute gastric bleeding and chronic metabolic acidosis and scarring.
benign >1 cell type tumor
c - myc gene
iron poisoning
Necrosis

28. ADH
alpha - fetoprotein
Reversible - plasias
causes of decreased ESR
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms

29. Melanoma - basal cell carcinoma - and especially squamous cell carcinomas of the skin.
paraneoplastic effects of small cell lung carcinoma
Neoplasm associated with xeroderma pigmentosum (albinism)
APC gene
Primary tumors that met to brain

30. Malignant lymphoma
blood vessels benign tumor
immunodeficiency states
Primary tumors that met to brain
lung cancer incidence/mortality

31. Most human cancers - specifically Li - Fraumeni syndrome 17p tumor suppressor (blocks G1 to S phase progression)
Barrett's esophagus (chronic GI reflux)
Leukocyte extravasation: migration
p53 gene
Pale infarcts

32. ACTH or ACTH- like peptide
Leading cause of death in the US
Primary tumors that met to bone
TRAP
paraneoplastic effects of small cell lung carcinoma

33. Tumor marker: (Normal in fetus). Hepatocellular carcinomas. Nonseminomatous germ cell tumors of the testis.
iron poisoning
cirrosis (alcohol - hepB or C)
alpha - fetoprotein
Neoplasm associated with xeroderma pigmentosum (albinism)

34. Lymphoma

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35. Hyperuricemia (excess NA turnover)
paraneoplastic effects of leukemias and lymphomas
Leukocyte extravasation: diapedesis
Where you see Psammoma bodies
DCC gene

36. Papillary (thyroid) - Serous (ovary) - Meningioma - Mesothelioma
Where you see Psammoma bodies
extrinsic apoptosis
smooth muscle benign tumor
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.

37. Larynx (SqCC) - lung (SqCC and SCC) - kidney (renal cell carcinoma) - bladder (transitional cell carcinoma)
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)
cigarette smoke target
DPC gene
NF2 gene

38. Tumor marker: thyroid medullary carcinoma
paraneoplastic effects of small cell lung carcinoma
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)
CA-125
calcitonin

39. Macrophages and lymphocytes. Persistant destruction and repair.
Chronic inflammatory mediators
N- myc gene
skeletal muscle malignant tumor
aflatoxin target

40. Tumor marker: melanoma - neural tumors - astrocytomas
prostate cancer incidence/mortality
DPC gene
S-100
blood vessels malignant tumor

41. Neuroblastoma transcription factor (oncogene)
N- myc gene
Prostatic acid phosphatase
Where you see Psammoma bodies
primary amyloidosis

42. Gastric adenocacinoma
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants
beta - hCG
Free radical eliminators
causes of increased ESR

43. Tumor marker: mets to bone - obstructive biliary disease - Paget's
paraneoplastic effects of leukemias and lymphomas
Alk - phos
vinyl chloride target
N- myc gene

44. Squamous cell carcinoma of skin
Neoplasm associated with actinic keratosis
causes of decreased ESR
asbestos target
Primary tumors that met to liver

45. Infections - inflammation - cancer - pregnancy - SLE
smooth muscle malignant tumor
causes of increased ESR
ulcerative colitis
p16 gene

46. Antibodies to presynaptic Ca2+ channels at NM junction
Autoimmune (Hashimoto's - myasthenia gravis)
Leukocyte extravasation: diapedesis
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants
paraneoplastic effects of thymoma - small cell lung carcinoma

47. Adenocarcinoma - papillary carcinoma
primary amyloidosis
granulomatous disease
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)
malignant epithelial tumor

48. Tumor marker: ovarian - malignant epithelial tumors.
Barrett's esophagus (chronic GI reflux)
Free radical cell damage
Neoplasm associated with xeroderma pigmentosum (albinism)
CA-125

49. Bacterial products (CLIK):C5a - LTB4 - IL-8 - Kallikrein
aflatoxin target
bone malignant tumor
Leukocyte extravasation: migration
paraneoplastic effects of leukemias and lymphomas

50. Rhabdomyoma
skeletal muscle benign tumor
vinyl chloride target
Necrosis
causes of decreased ESR

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First Aid Basics

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