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First Aid Basics

Subjects : health-sciences, first-aid

Instructions:

Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can study here.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Neurofibromatosis type 2 22q tumor suppressor (key type 2=22)
smooth muscle benign tumor
PSA
NF2 gene
N- myc gene

2. Breast - ovarian and gastric carcinomas tyrosine kinase (oncogene)
CA-19-9
erb - B2 gene
skeletal muscle malignant tumor
paraneoplastic effects of thymoma - small cell lung carcinoma

3. Macrophages and lymphocytes. Persistant destruction and repair.
Primary tumors that met to bone
fat malignant tumor
Chronic inflammatory mediators
ulcerative colitis

4. Angiosarcoma
blood vessels malignant tumor
beta - hCG
Primary tumors that met to bone
Free radical cell damage

5. Membrane lipid peroxidation - protein modification and DNA breakage.
benign epithelial tumor
Free radical cell damage
NF2 gene
AIDS

6. ACTH or ACTH- like peptide
CEA
paraneoplastic effects of small cell lung carcinoma
PSA
Free radical cell damage

7. Pancreatic cancer (Deleted in Pancreatic Cancer) 18q tumor suppressor
L- myc gene
DPC gene
ret gene
p53 gene

8. Colonic adenocarcinoma
nitrosamines (smoked foods) target
paraneoplastic effects of small cell lung carcinoma
ulcerative colitis
benign >1 cell type tumor

9. Hepatocellular carcinoma
Necrosis
acanthosis nigricans (hyperpig and epidermal thickening)
cirrosis (alcohol - hepB or C)
ulcerative colitis

10. Heart disease
Leading cause of death in the US
Irreversible - plasias
DCC gene
smooth muscle benign tumor

11. Aggressive malignant lymphomas (non - Hodgkin's) and Kaposi's sarcoma
ulcerative colitis
benign epithelial tumor
Free radical eliminators
AIDS

12. Neuroblastoma transcription factor (oncogene)
CA-19-9
N- myc gene
malignant mesenchyme tumor (general)
WT1 gene

13. Liver (angiosarcoma)
Primary tumors that met to bone
vinyl chloride target
PSA
Napthalene (aniline) dyes target

14. AL
c - kit gene
secondary amyloidosis (reactive systemic)
benign epithelial tumor
primary amyloidosis

15. Leiomyoma
Neoplasm associated with Down Syndrome
immunodeficiency states
c - myc gene
smooth muscle benign tumor

16. 32%/18% female
breast cancer incidence/mortality
PSA
Pale infarcts
APC gene

17. Retinoblastoma - osteosarcoma 13q tumor suppressor (blocks G1 to S phase progression)
asbestos target
immunodeficiency states
Leukocyte extravasation: diapedesis
Rb gene

18. Most human cancers - specifically Li - Fraumeni syndrome 17p tumor suppressor (blocks G1 to S phase progression)
Paget's bone disease
aflatoxin target
Leading cause of death in the US
p53 gene

19. Colon>stomach>pancreas>breast>lung (liver and lung are the most common places for mets)
Napthalene (aniline) dyes target
causes of increased ESR
vinyl chloride target
Primary tumors that met to liver

20. Anaplasia - neoplasia - desmoplasia (fibrous tissue formation in response to neoplasm)
asbestos target
Irreversible - plasias
extrinsic apoptosis
BRCA1 gene

21. Melanoma 9p tumor suppressor
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)
bone benign tumor
p16 gene
arsenic target

22. Osteoma
DPC gene
ulcerative colitis
bone benign tumor
TRAP

23. Esophageal adenocarcinoma

24. GIST cytokine receptor (oncogene)
c - kit gene
benign epithelial tumor
calcitonin
malignant epithelial tumor

25. Vascular: ICAM-1 Leukocyte: LFA-1 (integrin)
abl gene
paraneoplastic effects of leukemias and lymphomas
Leukocyte extravasation: tight binding
Alkylating agents target

26. Skin (SqCC) - liver (angiosarcoma)
paraneoplastic effects of thymoma - small cell lung carcinoma
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
paraneoplastic effects of leukemias and lymphomas
arsenic target

27. Tumor marker: carcinoembryonic Ag Very nonspecific
Where you see Psammoma bodies
CA-125
CEA
DCC gene

28. Lymphoma

29. Tumor marker: prostate carcinoma marker.
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)
Prostatic acid phosphatase
radiation exposure
NF1 gene

30. Restoration of normal structure - granulation tissue (vascularized + fibrosis) - abscess (fibrosis + pus) - fistula or scarring (collagen).
bone malignant tumor
Resolution of inflammation
Neoplasm associated with Down Syndrome
Rb gene

31. Enzymes: catalase - superoxide dismutase - glutathione peroxidase.Vitamins: ACE Spontaneous decay
Neoplasm associated with Down Syndrome
bone benign tumor
Free radical eliminators
TRAP

32. Prostate (blastic) - thyroid - testes - breast (lytic and blastic) - lung (lytic) - kidney (breast and prostate are most common)
Leukocyte extravasation: migration
Reversible - plasias
Chronic inflammatory mediators
Primary tumors that met to bone

33. Hemangioma
blood vessels benign tumor
malignant epithelial tumor
ras gene
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms

34. MEN type II and III tyrosine kinase (oncogene)
breast cancer incidence/mortality
Resolution of inflammation
ret gene
APC gene

35. Rhabdomyoma
skeletal muscle benign tumor
Neoplasm associated with actinic keratosis
Necrosis
Irreversible - plasias

36. Erythropoietin
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
Neoplasm associated with actinic keratosis
Second - leading cause of death in the US
Bombesin

37. 32%/13% male
Pale infarcts
prostate cancer incidence/mortality
Paget's bone disease
malignant mesenchyme tumor (general)

38. Follicular and undifferentiated lymphomas anti - apoptotic molecule (oncogene)
beta - hCG
bcl -2 gene
p16 gene
Leukocyte extravasation: rolling

39. TB - fungal infections - syphilis - leprosy - cat scratch fever - sarcoid - Crohn's - Berylliosis.
c - kit gene
granulomatous disease
Free radical cell damage
blood vessels benign tumor

40. Tumor marker: Screen for prostate carcinoma. Can also be elevated in BPH and prostatitis.
PSA
causes of increased ESR
Primary tumors that met to brain
malignant epithelial tumor

41. Squamous cell carcinoma of skin
Chronic inflammatory mediators
smooth muscle malignant tumor
Neoplasm associated with actinic keratosis
malignant mesenchyme tumor (general)

42. Tumor marker: Hydatifiform moles - choriocarcinomas - gestational trophoblastic tumors.
dysplastic nevus
primary amyloidosis
beta - hCG
BRCA1 gene

43. Vascular: E and P- selectin Leukocyte: Sialyl Lewis
nitrosamines (smoked foods) target
Leukocyte extravasation: rolling
blood cell malignant tumors
Red (hemorrhagic) infarcts

44. PTH- related peptide - TGF- beta - TNF - IL-1
paraneoplastic effects of small cell lung carcinoma
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)
beta - hCG
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.

45. Tumor marker: (Normal in fetus). Hepatocellular carcinomas. Nonseminomatous germ cell tumors of the testis.
alpha - fetoprotein
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)
Prostatic acid phosphatase
Acute inflammatory mediators

46. Tumor marker: mets to bone - obstructive biliary disease - Paget's
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
granulomatous disease
calcitonin
Alk - phos

47. Hyperuricemia (excess NA turnover)
Necrosis
paraneoplastic effects of leukemias and lymphomas
erb - B2 gene
bone malignant tumor

48. Adenocarcinoma - papillary carcinoma
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.
p53 gene
prostate cancer incidence/mortality
malignant epithelial tumor

49. CML tyrosine kinase (oncogene)
Leukocyte extravasation: migration
abl gene
malignant epithelial tumor
p16 gene

50. Bladder (transitional cell carcinoma)
Napthalene (aniline) dyes target
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
causes of decreased ESR
malignant epithelial tumor