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First Aid Basics

Subjects : health-sciences, first-aid

Instructions:

Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can study here.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Hyperuricemia (excess NA turnover)
Leukocyte extravasation: diapedesis
Leukocyte extravasation: migration
paraneoplastic effects of leukemias and lymphomas
breast cancer incidence/mortality

2. Squamous cell carcinoma of the esophagus
Reversible - plasias
ret gene
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)
Second - leading cause of death in the US

3. Erythropoietin
cigarette smoke target
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
bcl -2 gene
Neoplasm associated with Down Syndrome

4. Prostate (blastic) - thyroid - testes - breast (lytic and blastic) - lung (lytic) - kidney (breast and prostate are most common)
Leukocyte extravasation: diapedesis
Primary tumors that met to bone
Napthalene (aniline) dyes target
c - myc gene

5. Aggressive malignant lymphomas (non - Hodgkin's) and Kaposi's sarcoma
paraneoplastic effects of small cell lung carcinoma
BRAC2 gene
blood cell malignant tumors
AIDS

6. Blood (leukemia)
Bombesin
CEA
NF2 gene
Alkylating agents target

7. ADH
benign epithelial tumor
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms
p16 gene
asbestos target

8. Burkitt's lymphoma transcription factor (oncogene)
Barrett's esophagus (chronic GI reflux)
c - myc gene
causes of increased ESR
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms

9. Squamous cell carcinoma of skin
lung cancer incidence/mortality
Neoplasm associated with actinic keratosis
Autoimmune (Hashimoto's - myasthenia gravis)
radiation exposure

10. Macrophages and lymphocytes. Persistant destruction and repair.
immunodeficiency states
Chronic inflammatory mediators
Rb gene
arsenic target

11. Neurofibromatosis type 2 22q tumor suppressor (key type 2=22)
skeletal muscle benign tumor
Necrosis
paraneoplastic effects of leukemias and lymphomas
NF2 gene

12. Pancreatic cancer (Deleted in Pancreatic Cancer) 18q tumor suppressor
Leukocyte extravasation: diapedesis
DPC gene
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants
beta - hCG

13. Lung - breast - skin (melanoma) - kidney (renal cell carcinoma) - GI.50% brain tumors are from mets
Primary tumors that met to brain
lung cancer incidence/mortality
Leukocyte extravasation: rolling
malignant mesenchyme tumor (general)

14. Bacterial products (CLIK):C5a - LTB4 - IL-8 - Kallikrein
Leukocyte extravasation: migration
intrinsic apoptosis
malignant mesenchyme tumor (general)
nitrosamines (smoked foods) target

15. Adenoma - papilloma
DPC gene
benign epithelial tumor
paraneoplastic effects of thymoma - small cell lung carcinoma
c - kit gene

16. Antibodies to presynaptic Ca2+ channels at NM junction
paraneoplastic effects of thymoma - small cell lung carcinoma
acanthosis nigricans (hyperpig and epidermal thickening)
bone malignant tumor
paraneoplastic effects of leukemias and lymphomas

17. Lymphoma

18. Tumor marker: ovarian - malignant epithelial tumors.
Napthalene (aniline) dyes target
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)
CA-125
Rb gene

19. Follicular and undifferentiated lymphomas anti - apoptotic molecule (oncogene)
bcl -2 gene
granulomatous disease
Colon and rectal cancer incidence
DCC gene

20. Colorectal cancer (assoc with FAP) 5q tumor suppressor
malignant mesenchyme tumor (general)
S-100
immunodeficiency states
APC gene

21. Malignant melanoma
CA-125
bone benign tumor
dysplastic nevus
erb - B2 gene

22. ACTH or ACTH- like peptide
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms
asbestos target
paraneoplastic effects of small cell lung carcinoma
beta - hCG

23. Colon carcinoma GTPase (oncogene)
ras gene
acanthosis nigricans (hyperpig and epidermal thickening)
arsenic target
CA-19-9

24. Liposarcoma
Acute inflammatory mediators
Primary tumors that met to brain
fat malignant tumor
Where you see Psammoma bodies

25. Ligand - receptor interactions. Release of perforin and granzyme B.
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms
smooth muscle benign tumor
extrinsic apoptosis
Red (hemorrhagic) infarcts

26. Colon>stomach>pancreas>breast>lung (liver and lung are the most common places for mets)
Primary tumors that met to liver
Resolution of inflammation
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.
Where you see Psammoma bodies

27. Sarcoma - papillary thyroid cancer
Neoplasm associated with xeroderma pigmentosum (albinism)
Rb gene
radiation exposure
Second - leading cause of death in the US

28. Enzymes: catalase - superoxide dismutase - glutathione peroxidase.Vitamins: ACE Spontaneous decay
causes of increased ESR
Free radical eliminators
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)
blood cell malignant tumors

29. Tumor marker: Screen for prostate carcinoma. Can also be elevated in BPH and prostatitis.
vinyl chloride target
NF2 gene
Prostatic acid phosphatase
PSA

30. Papillary (thyroid) - Serous (ovary) - Meningioma - Mesothelioma
c - kit gene
Where you see Psammoma bodies
smooth muscle malignant tumor
Chronic inflammatory mediators

31. Liver (hepatocellular carcinoma)
CA-125
aflatoxin target
Leukocyte extravasation: migration
Neoplasm associated with actinic keratosis

32. Hepatocellular carcinoma
cirrosis (alcohol - hepB or C)
Neoplasm associated with actinic keratosis
intrinsic apoptosis
BRCA1 gene

33. Vascular: E and P- selectin Leukocyte: Sialyl Lewis
Resolution of inflammation
dysplastic nevus
Leukocyte extravasation: rolling
Irreversible - plasias

34. Larynx (SqCC) - lung (SqCC and SCC) - kidney (renal cell carcinoma) - bladder (transitional cell carcinoma)
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.
cigarette smoke target
WT1 gene
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants

35. Restoration of normal structure - granulation tissue (vascularized + fibrosis) - abscess (fibrosis + pus) - fistula or scarring (collagen).
Barrett's esophagus (chronic GI reflux)
Neoplasm associated with actinic keratosis
paraneoplastic effects of thymoma - small cell lung carcinoma
Resolution of inflammation

36. Colon cancer (Deleted in Colon Cancer) 18q tumor suppressor
DCC gene
PSA
p16 gene
Primary tumors that met to brain

37. Bladder (transitional cell carcinoma)
ulcerative colitis
APC gene
Napthalene (aniline) dyes target
breast cancer incidence/mortality

38. Leukemia - lymphoma
secondary amyloidosis (reactive systemic)
blood cell malignant tumors
WT1 gene
vinyl chloride target

39. Tumor marker: neuroblastoma - lung and gastric cancer
Bombesin
c - myc gene
Leukocyte extravasation: diapedesis
secondary amyloidosis (reactive systemic)

40. Female 13%/23% and rising Male 16%/33% (mortality has plateaued)
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)
lung cancer incidence/mortality
ulcerative colitis
Where you see Psammoma bodies

41. Sarcoma
Necrosis
malignant mesenchyme tumor (general)
breast cancer incidence/mortality
fat benign tumor

42. Lung - liver - intestine or following reperfusion.
fat malignant tumor
Leukocyte extravasation: diapedesis
malignant >1 cell type tumor
Red (hemorrhagic) infarcts

43. PECAM-1
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants
S-100
Leukocyte extravasation: diapedesis
ras gene

44. Melanoma 9p tumor suppressor
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms
p16 gene
Necrosis
BRAC2 gene

45. Osteosarcoma
ret gene
bone malignant tumor
malignant epithelial tumor
benign epithelial tumor

46. Tumor marker: melanoma - neural tumors - astrocytomas
Napthalene (aniline) dyes target
S-100
Free radical eliminators
cigarette smoke target

47. Osteoma
bone benign tumor
Prostatic acid phosphatase
cirrosis (alcohol - hepB or C)
APC gene

48. Leiomyoma
intrinsic apoptosis
blood vessels benign tumor
smooth muscle benign tumor
bone malignant tumor

49. Mature teratoma in women
alpha - fetoprotein
benign >1 cell type tumor
primary amyloidosis
beta - hCG

50. Lung (mesothelioma and bronchogenic carcinoma)
asbestos target
extrinsic apoptosis
beta - hCG
fat malignant tumor