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First Aid Basics

Subjects : health-sciences, first-aid

Instructions:

Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can study here.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Sarcoma
Rb gene
erb - B2 gene
malignant mesenchyme tumor (general)
paraneoplastic effects of leukemias and lymphomas

2. Papillary (thyroid) - Serous (ovary) - Meningioma - Mesothelioma
iron poisoning
Where you see Psammoma bodies
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)
asbestos target

3. Lymphoma

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4. Vascular: E and P- selectin Leukocyte: Sialyl Lewis
WT1 gene
c - myc gene
Where you see Psammoma bodies
Leukocyte extravasation: rolling

5. Colorectal cancer (assoc with FAP) 5q tumor suppressor
ret gene
smooth muscle malignant tumor
APC gene
intrinsic apoptosis

6. Osteosarcoma
bone malignant tumor
primary amyloidosis
Leukocyte extravasation: diapedesis
DPC gene

7. Leiomyoma
smooth muscle benign tumor
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)
paraneoplastic effects of leukemias and lymphomas
fat benign tumor

8. 32%/13% male
intrinsic apoptosis
prostate cancer incidence/mortality
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)
Neoplasm associated with actinic keratosis

9. Retinoblastoma - osteosarcoma 13q tumor suppressor (blocks G1 to S phase progression)
Reversible - plasias
Rb gene
arsenic target
fat malignant tumor

10. Skin (SqCC) - liver (angiosarcoma)
Napthalene (aniline) dyes target
arsenic target
AIDS
Autoimmune (Hashimoto's - myasthenia gravis)

11. Lipoma
malignant epithelial tumor
fat benign tumor
abl gene
Colon and rectal cancer incidence

12. Heart disease
Leading cause of death in the US
Primary tumors that met to liver
Acute inflammatory mediators
secondary amyloidosis (reactive systemic)

13. Wilms' tumor 11p tumor suppressor
malignant mesenchyme tumor (general)
bone malignant tumor
WT1 gene
BRAC2 gene

14. Tumor marker: neuroblastoma - lung and gastric cancer
Colon and rectal cancer incidence
Bombesin
Irreversible - plasias
Alkylating agents target

15. PTH- related peptide - TGF- beta - TNF - IL-1
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants
NF2 gene
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.
paraneoplastic effects of small cell lung carcinoma

16. Squamous cell carcinoma of skin
Neoplasm associated with actinic keratosis
Pale infarcts
skeletal muscle benign tumor
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants

17. Tumor marker: tartrate - resistant acid phosphatase. Hairy cell leukemia (B- cell neoplasm)
Neoplasm associated with actinic keratosis
TRAP
N- myc gene
DCC gene

18. All - AML
CA-19-9
extrinsic apoptosis
Paget's bone disease
Neoplasm associated with Down Syndrome

19. TB - fungal infections - syphilis - leprosy - cat scratch fever - sarcoid - Crohn's - Berylliosis.
Primary tumors that met to brain
cigarette smoke target
granulomatous disease
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms

20. Mature teratoma in women
Free radical cell damage
paraneoplastic effects of small cell lung carcinoma
benign >1 cell type tumor
radiation exposure

21. Hemangioma
blood vessels benign tumor
iron poisoning
paraneoplastic effects of small cell lung carcinoma
vinyl chloride target

22. Most human cancers - specifically Li - Fraumeni syndrome 17p tumor suppressor (blocks G1 to S phase progression)
CA-125
vinyl chloride target
NF1 gene
p53 gene

23. Membrane lipid peroxidation - protein modification and DNA breakage.
Free radical cell damage
smooth muscle benign tumor
p16 gene
aflatoxin target

24. Malignant lymphoma
bcl -2 gene
prostate cancer incidence/mortality
Second - leading cause of death in the US
immunodeficiency states

25. Colon cancer (Deleted in Colon Cancer) 18q tumor suppressor
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)
extrinsic apoptosis
Leukocyte extravasation: migration
DCC gene

26. During embryogenesis - hormone induction and atrophy. Increased mitochondrial permeability and cytochrome c release. Increase Bax (pro - apoptotic) - decreased Bcl -2 (anti - apopotic).
WT1 gene
intrinsic apoptosis
c - kit gene
PSA

27. Sickle cell (altered shape) - polycythemia (too many) - CHF (unknown)
skeletal muscle benign tumor
alpha - fetoprotein
causes of decreased ESR
Paget's bone disease

28. Liposarcoma
fat malignant tumor
malignant mesenchyme tumor (general)
paraneoplastic effects of leukemias and lymphomas
ras gene

29. Astrocytoma - angiomyolipoma - cardiac rhabdomyoma
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms
ras gene
malignant epithelial tumor

30. Colon>stomach>pancreas>breast>lung (liver and lung are the most common places for mets)
causes of decreased ESR
Primary tumors that met to liver
paraneoplastic effects of thymoma - small cell lung carcinoma
radiation exposure

31. Female 13%/23% and rising Male 16%/33% (mortality has plateaued)
Rb gene
Napthalene (aniline) dyes target
lung cancer incidence/mortality
Acute inflammatory mediators

32. Visceral malignancy (stomach - lung - breast - uterus)
iron poisoning
acanthosis nigricans (hyperpig and epidermal thickening)
Primary tumors that met to brain
blood cell malignant tumors

33. Esophagus - stomach
radiation exposure
nitrosamines (smoked foods) target
Necrosis
fat malignant tumor

34. Lung - breast - skin (melanoma) - kidney (renal cell carcinoma) - GI.50% brain tumors are from mets
Primary tumors that met to brain
immunodeficiency states
paraneoplastic effects of thymoma - small cell lung carcinoma
Pale infarcts

35. Hyperplasia - metaplasia - dysplasia
NF2 gene
paraneoplastic effects of thymoma - small cell lung carcinoma
NF1 gene
Reversible - plasias

36. AL
primary amyloidosis
AIDS
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
cirrosis (alcohol - hepB or C)

37. Prostate (blastic) - thyroid - testes - breast (lytic and blastic) - lung (lytic) - kidney (breast and prostate are most common)
Irreversible - plasias
malignant mesenchyme tumor (general)
Alk - phos
Primary tumors that met to bone

38. GIST cytokine receptor (oncogene)
Alkylating agents target
Leukocyte extravasation: tight binding
c - kit gene
benign epithelial tumor

39. Erythropoietin
paraneoplastic effects of small cell lung carcinoma
Neoplasm associated with xeroderma pigmentosum (albinism)
Resolution of inflammation
paraneoplastic effects of renal cell carcinoma - hemangioblastoma

40. Sarcoma - papillary thyroid cancer
Napthalene (aniline) dyes target
radiation exposure
ras gene
smooth muscle malignant tumor

41. Tumor marker: pancreatic adenocarcinoma
CCl4 target
WT1 gene
CA-19-9
breast cancer incidence/mortality

42. Tumor marker: melanoma - neural tumors - astrocytomas
S-100
Resolution of inflammation
Napthalene (aniline) dyes target
APC gene

43. Neurofibromatosis type 1 17q tumor suppressor
beta - hCG
NF1 gene
Primary tumors that met to brain
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)

44. Liver (centrilobular necrosis - fatty change)
benign >1 cell type tumor
BRCA1 gene
CCl4 target
immunodeficiency states

45. Caused by peroxidation of membrane lipids. Causes acute gastric bleeding and chronic metabolic acidosis and scarring.
iron poisoning
fat benign tumor
erb - B2 gene
CA-19-9

46. Gastric adenocacinoma
APC gene
benign >1 cell type tumor
PSA
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants

47. Adenocarcinoma - papillary carcinoma
malignant epithelial tumor
Primary tumors that met to bone
Red (hemorrhagic) infarcts
Pale infarcts

48. Tumor marker: mets to bone - obstructive biliary disease - Paget's
Alk - phos
Primary tumors that met to brain
breast cancer incidence/mortality
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants

49. Cancer
paraneoplastic effects of thymoma - small cell lung carcinoma
p53 gene
causes of decreased ESR
Second - leading cause of death in the US

50. Pancreatic cancer (Deleted in Pancreatic Cancer) 18q tumor suppressor
DPC gene
alpha - fetoprotein
CEA
acanthosis nigricans (hyperpig and epidermal thickening)