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First Aid Basics

Subjects : health-sciences, first-aid

Instructions:

Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can study here.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Neuroblastoma transcription factor (oncogene)
N- myc gene
WT1 gene
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
alpha - fetoprotein

2. Macrophages and lymphocytes. Persistant destruction and repair.
Paget's bone disease
Chronic inflammatory mediators
L- myc gene
malignant >1 cell type tumor

3. CML tyrosine kinase (oncogene)
p16 gene
abl gene
Primary tumors that met to liver
arsenic target

4. Blood (leukemia)
Alkylating agents target
cirrosis (alcohol - hepB or C)
breast cancer incidence/mortality
lung cancer incidence/mortality

5. Most human cancers - specifically Li - Fraumeni syndrome 17p tumor suppressor (blocks G1 to S phase progression)
Chronic inflammatory mediators
blood vessels malignant tumor
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
p53 gene

6. Osteoma
CA-19-9
bone benign tumor
aflatoxin target
S-100

7. Hemangioma
paraneoplastic effects of small cell lung carcinoma
iron poisoning
blood vessels benign tumor
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)

8. Breast and ovarian cancer 17q tumor suppressor (DNA repair protein)
BRCA1 gene
alpha - fetoprotein
N- myc gene
c - myc gene

9. Sarcoma
APC gene
skeletal muscle malignant tumor
malignant mesenchyme tumor (general)
Primary tumors that met to brain

10. Colorectal cancer (assoc with FAP) 5q tumor suppressor
Neoplasm associated with actinic keratosis
acanthosis nigricans (hyperpig and epidermal thickening)
APC gene
fat malignant tumor

11. Tumor marker: pancreatic adenocarcinoma
skeletal muscle malignant tumor
c - kit gene
CA-19-9
abl gene

12. Osteosarcoma
iron poisoning
Leading cause of death in the US
bone benign tumor
bone malignant tumor

13. Neutrophils (eos in the gut) - plus other granular leukocytes and antibodies.
Acute inflammatory mediators
skeletal muscle malignant tumor
L- myc gene
nitrosamines (smoked foods) target

14. Pancreatic cancer (Deleted in Pancreatic Cancer) 18q tumor suppressor
Necrosis
S-100
nitrosamines (smoked foods) target
DPC gene

15. Breast cancer 13q tumor suppressor (DNA repair protein)
BRAC2 gene
bcl -2 gene
NF1 gene
CCl4 target

16. Adenocarcinoma - papillary carcinoma
vinyl chloride target
malignant epithelial tumor
acanthosis nigricans (hyperpig and epidermal thickening)
DCC gene

17. Malignant melanoma
dysplastic nevus
fat malignant tumor
NF2 gene
prostate cancer incidence/mortality

18. Follicular and undifferentiated lymphomas anti - apoptotic molecule (oncogene)
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants
malignant mesenchyme tumor (general)
bcl -2 gene
vinyl chloride target

19. Vascular: E and P- selectin Leukocyte: Sialyl Lewis
acanthosis nigricans (hyperpig and epidermal thickening)
CEA
Leukocyte extravasation: rolling
Colon and rectal cancer incidence

20. Liver (angiosarcoma)
bone malignant tumor
Neoplasm associated with actinic keratosis
Barrett's esophagus (chronic GI reflux)
vinyl chloride target

21. Prostate (blastic) - thyroid - testes - breast (lytic and blastic) - lung (lytic) - kidney (breast and prostate are most common)
Primary tumors that met to bone
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants
iron poisoning
p53 gene

22. ACTH or ACTH- like peptide
Autoimmune (Hashimoto's - myasthenia gravis)
PSA
vinyl chloride target
paraneoplastic effects of small cell lung carcinoma

23. Malignant lymphoma
immunodeficiency states
malignant epithelial tumor
vinyl chloride target
paraneoplastic effects of renal cell carcinoma - hemangioblastoma

24. Hyperuricemia (excess NA turnover)
Colon and rectal cancer incidence
paraneoplastic effects of leukemias and lymphomas
skeletal muscle malignant tumor
BRAC2 gene

25. Colon>stomach>pancreas>breast>lung (liver and lung are the most common places for mets)
Primary tumors that met to liver
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms
Second - leading cause of death in the US
malignant >1 cell type tumor

26. Liver (hepatocellular carcinoma)
Reversible - plasias
Paget's bone disease
alpha - fetoprotein
aflatoxin target

27. Female 13%/23% and rising Male 16%/33% (mortality has plateaued)
Leukocyte extravasation: migration
p16 gene
skeletal muscle benign tumor
lung cancer incidence/mortality

28. Tumor marker: neuroblastoma - lung and gastric cancer
BRCA1 gene
Second - leading cause of death in the US
Bombesin
dysplastic nevus

29. Lipoma
N- myc gene
Leukocyte extravasation: diapedesis
fat benign tumor
paraneoplastic effects of small cell lung carcinoma

30. Liver (centrilobular necrosis - fatty change)
DCC gene
BRCA1 gene
c - myc gene
CCl4 target

31. Esophageal adenocarcinoma

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32. Vascular: ICAM-1 Leukocyte: LFA-1 (integrin)
DPC gene
Leukocyte extravasation: tight binding
Rb gene
Barrett's esophagus (chronic GI reflux)

33. Tumor marker: melanoma - neural tumors - astrocytomas
S-100
erb - B2 gene
paraneoplastic effects of thymoma - small cell lung carcinoma
malignant mesenchyme tumor (general)

34. Tumor marker: Screen for prostate carcinoma. Can also be elevated in BPH and prostatitis.
PSA
bcl -2 gene
iron poisoning
DPC gene

35. Lung - breast - skin (melanoma) - kidney (renal cell carcinoma) - GI.50% brain tumors are from mets
aflatoxin target
PSA
Primary tumors that met to brain
BRCA1 gene

36. GIST cytokine receptor (oncogene)
immunodeficiency states
c - kit gene
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms
Neoplasm associated with actinic keratosis

37. Squamous cell carcinoma of skin
CEA
Neoplasm associated with actinic keratosis
bone malignant tumor
asbestos target

38. Rhabdomyoma
beta - hCG
extrinsic apoptosis
abl gene
skeletal muscle benign tumor

39. Tumor marker: thyroid medullary carcinoma
calcitonin
CCl4 target
Rb gene
dysplastic nevus

40. Tumor marker: (Normal in fetus). Hepatocellular carcinomas. Nonseminomatous germ cell tumors of the testis.
Leukocyte extravasation: migration
alpha - fetoprotein
Neoplasm associated with actinic keratosis
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms

41. Infections - inflammation - cancer - pregnancy - SLE
S-100
DCC gene
Second - leading cause of death in the US
causes of increased ESR

42. Colon cancer (Deleted in Colon Cancer) 18q tumor suppressor
DCC gene
Free radical eliminators
Neoplasm associated with Down Syndrome
Acute inflammatory mediators

43. Tumor marker: carcinoembryonic Ag Very nonspecific
NF1 gene
CEA
Leukocyte extravasation: tight binding
erb - B2 gene

44. Squamous cell carcinoma of the esophagus
Leukocyte extravasation: rolling
Neoplasm associated with Down Syndrome
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)
Prostatic acid phosphatase

45. Heart disease
Leading cause of death in the US
Alkylating agents target
TRAP
AIDS

46. Tumor marker: tartrate - resistant acid phosphatase. Hairy cell leukemia (B- cell neoplasm)
vinyl chloride target
APC gene
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)
TRAP

47. Leiomyoma
smooth muscle benign tumor
Leading cause of death in the US
acanthosis nigricans (hyperpig and epidermal thickening)
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)

48. Melanoma - basal cell carcinoma - and especially squamous cell carcinomas of the skin.
fat malignant tumor
blood vessels benign tumor
Neoplasm associated with xeroderma pigmentosum (albinism)
abl gene

49. Retinoblastoma - osteosarcoma 13q tumor suppressor (blocks G1 to S phase progression)
skeletal muscle benign tumor
beta - hCG
erb - B2 gene
Rb gene

50. Rhabdomyosarcoma
iron poisoning
ras gene
skeletal muscle malignant tumor
blood vessels malignant tumor