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First Aid Basics

Subjects : health-sciences, first-aid

Instructions:

Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can study here.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Female 13%/23% and rising Male 16%/33% (mortality has plateaued)
lung cancer incidence/mortality
Resolution of inflammation
benign >1 cell type tumor
prostate cancer incidence/mortality

2. Mature teratoma in women
Resolution of inflammation
L- myc gene
benign >1 cell type tumor
Barrett's esophagus (chronic GI reflux)

3. Antibodies to presynaptic Ca2+ channels at NM junction
granulomatous disease
cigarette smoke target
paraneoplastic effects of thymoma - small cell lung carcinoma
Leukocyte extravasation: migration

4. Macrophages and lymphocytes. Persistant destruction and repair.
Chronic inflammatory mediators
ras gene
blood vessels malignant tumor
abl gene

5. Colonic adenocarcinoma
Colon and rectal cancer incidence
ulcerative colitis
Napthalene (aniline) dyes target
TRAP

6. MEN type II and III tyrosine kinase (oncogene)
ret gene
PSA
erb - B2 gene
blood vessels benign tumor

7. Bacterial products (CLIK):C5a - LTB4 - IL-8 - Kallikrein
smooth muscle malignant tumor
Resolution of inflammation
Leukocyte extravasation: migration
granulomatous disease

8. ADH
L- myc gene
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms
granulomatous disease
Alkylating agents target

9. Most human cancers - specifically Li - Fraumeni syndrome 17p tumor suppressor (blocks G1 to S phase progression)
p53 gene
skeletal muscle benign tumor
p16 gene
L- myc gene

10. Hyperplasia - metaplasia - dysplasia
APC gene
Reversible - plasias
DCC gene
Prostatic acid phosphatase

11. Squamous cell carcinoma of skin
dysplastic nevus
Neoplasm associated with actinic keratosis
NF1 gene
causes of increased ESR

12. Pancreatic cancer (Deleted in Pancreatic Cancer) 18q tumor suppressor
Neoplasm associated with xeroderma pigmentosum (albinism)
Leukocyte extravasation: rolling
DPC gene
extrinsic apoptosis

13. Adenocarcinoma - papillary carcinoma
Leading cause of death in the US
paraneoplastic effects of leukemias and lymphomas
malignant epithelial tumor
Napthalene (aniline) dyes target

14. CML tyrosine kinase (oncogene)
abl gene
Neoplasm associated with xeroderma pigmentosum (albinism)
arsenic target
PSA

15. Papillary (thyroid) - Serous (ovary) - Meningioma - Mesothelioma
Leading cause of death in the US
Napthalene (aniline) dyes target
malignant epithelial tumor
Where you see Psammoma bodies

16. Lymphoma

17. During embryogenesis - hormone induction and atrophy. Increased mitochondrial permeability and cytochrome c release. Increase Bax (pro - apoptotic) - decreased Bcl -2 (anti - apopotic).
CCl4 target
intrinsic apoptosis
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)
immunodeficiency states

18. Rhabdomyosarcoma
Neoplasm associated with xeroderma pigmentosum (albinism)
skeletal muscle malignant tumor
Colon and rectal cancer incidence
Primary tumors that met to liver

19. All - AML
cigarette smoke target
Neoplasm associated with Down Syndrome
ulcerative colitis
paraneoplastic effects of thymoma - small cell lung carcinoma

20. Liver (centrilobular necrosis - fatty change)
asbestos target
vinyl chloride target
CCl4 target
L- myc gene

21. Erythropoietin
p16 gene
BRAC2 gene
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
fat malignant tumor

22. Malignant lymphoma
Primary tumors that met to liver
Free radical cell damage
immunodeficiency states
malignant mesenchyme tumor (general)

23. Colon cancer (Deleted in Colon Cancer) 18q tumor suppressor
immunodeficiency states
Necrosis
Neoplasm associated with xeroderma pigmentosum (albinism)
DCC gene

24. Breast and ovarian cancer 17q tumor suppressor (DNA repair protein)
p53 gene
BRCA1 gene
Primary tumors that met to brain
paraneoplastic effects of leukemias and lymphomas

25. 32%/13% male
CA-19-9
prostate cancer incidence/mortality
Prostatic acid phosphatase
c - kit gene

26. Adenoma - papilloma
blood vessels benign tumor
Primary tumors that met to liver
ulcerative colitis
benign epithelial tumor

27. Skin (SqCC) - liver (angiosarcoma)
c - kit gene
ras gene
arsenic target
secondary amyloidosis (reactive systemic)

28. Esophageal adenocarcinoma

29. Colon>stomach>pancreas>breast>lung (liver and lung are the most common places for mets)
extrinsic apoptosis
Primary tumors that met to liver
skeletal muscle benign tumor
secondary amyloidosis (reactive systemic)

30. TB - fungal infections - syphilis - leprosy - cat scratch fever - sarcoid - Crohn's - Berylliosis.
Colon and rectal cancer incidence
calcitonin
granulomatous disease
CA-125

31. Larynx (SqCC) - lung (SqCC and SCC) - kidney (renal cell carcinoma) - bladder (transitional cell carcinoma)
smooth muscle malignant tumor
intrinsic apoptosis
p53 gene
cigarette smoke target

32. PTH- related peptide - TGF- beta - TNF - IL-1
Acute inflammatory mediators
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.
aflatoxin target
nitrosamines (smoked foods) target

33. Anaplasia - neoplasia - desmoplasia (fibrous tissue formation in response to neoplasm)
lung cancer incidence/mortality
fat benign tumor
N- myc gene
Irreversible - plasias

34. Prostate (blastic) - thyroid - testes - breast (lytic and blastic) - lung (lytic) - kidney (breast and prostate are most common)
malignant >1 cell type tumor
bone benign tumor
Primary tumors that met to bone
CCl4 target

35. GIST cytokine receptor (oncogene)
CEA
c - kit gene
Napthalene (aniline) dyes target
PSA

36. Solid tissues with single blood supply. Heart - kidney and spleen.
Leukocyte extravasation: migration
Leukocyte extravasation: tight binding
Pale infarcts
Leukocyte extravasation: diapedesis

37. Tumor marker: neuroblastoma - lung and gastric cancer
Alkylating agents target
Bombesin
PSA
p16 gene

38. Leukemia - lymphoma
vinyl chloride target
NF2 gene
blood cell malignant tumors
beta - hCG

39. Tumor marker: carcinoembryonic Ag Very nonspecific
NF2 gene
DPC gene
DCC gene
CEA

40. Breast - ovarian and gastric carcinomas tyrosine kinase (oncogene)
prostate cancer incidence/mortality
immunodeficiency states
erb - B2 gene
abl gene

41. ACTH or ACTH- like peptide
ras gene
blood vessels malignant tumor
Alkylating agents target
paraneoplastic effects of small cell lung carcinoma

42. Secondary osteosarcoma and fibrosarcoma

43. Vascular: ICAM-1 Leukocyte: LFA-1 (integrin)
alpha - fetoprotein
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
Leukocyte extravasation: tight binding

44. AA
causes of increased ESR
secondary amyloidosis (reactive systemic)
lung cancer incidence/mortality
Prostatic acid phosphatase

45. Lung (mesothelioma and bronchogenic carcinoma)
blood vessels malignant tumor
Primary tumors that met to brain
asbestos target
ulcerative colitis

46. Retinoblastoma - osteosarcoma 13q tumor suppressor (blocks G1 to S phase progression)
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
Rb gene
asbestos target
c - myc gene

47. Astrocytoma - angiomyolipoma - cardiac rhabdomyoma
intrinsic apoptosis
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)
erb - B2 gene

48. Ligand - receptor interactions. Release of perforin and granzyme B.
lung cancer incidence/mortality
Neoplasm associated with actinic keratosis
p53 gene
extrinsic apoptosis

49. Burkitt's lymphoma transcription factor (oncogene)
breast cancer incidence/mortality
NF1 gene
c - myc gene
cirrosis (alcohol - hepB or C)

50. Membrane lipid peroxidation - protein modification and DNA breakage.
nitrosamines (smoked foods) target
alpha - fetoprotein
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
Free radical cell damage