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First Aid Basics

Subjects : health-sciences, first-aid

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. During embryogenesis - hormone induction and atrophy. Increased mitochondrial permeability and cytochrome c release. Increase Bax (pro - apoptotic) - decreased Bcl -2 (anti - apopotic).
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.
intrinsic apoptosis
ulcerative colitis
S-100

2. AA
secondary amyloidosis (reactive systemic)
Primary tumors that met to liver
L- myc gene
NF1 gene

3. AL
primary amyloidosis
fat malignant tumor
lung cancer incidence/mortality
paraneoplastic effects of renal cell carcinoma - hemangioblastoma

4. Breast cancer 13q tumor suppressor (DNA repair protein)
Paget's bone disease
benign epithelial tumor
BRAC2 gene
breast cancer incidence/mortality

5. Tumor marker: thyroid medullary carcinoma
calcitonin
vinyl chloride target
S-100
paraneoplastic effects of thymoma - small cell lung carcinoma

6. Squamous cell carcinoma of the esophagus
malignant epithelial tumor
p16 gene
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)
BRAC2 gene

7. Tumor marker: melanoma - neural tumors - astrocytomas
S-100
beta - hCG
Leukocyte extravasation: rolling
DCC gene

8. Adenocarcinoma - papillary carcinoma
Prostatic acid phosphatase
Paget's bone disease
primary amyloidosis
malignant epithelial tumor

9. Tumor marker: (Normal in fetus). Hepatocellular carcinomas. Nonseminomatous germ cell tumors of the testis.
S-100
alpha - fetoprotein
arsenic target
causes of decreased ESR

10. Lung - breast - skin (melanoma) - kidney (renal cell carcinoma) - GI.50% brain tumors are from mets
ulcerative colitis
p53 gene
Primary tumors that met to brain
Prostatic acid phosphatase

11. PTH- related peptide - TGF- beta - TNF - IL-1
p16 gene
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.
Primary tumors that met to liver
Where you see Psammoma bodies

12. Hyperuricemia (excess NA turnover)
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms
Pale infarcts
CA-125
paraneoplastic effects of leukemias and lymphomas

13. Colon carcinoma GTPase (oncogene)
Neoplasm associated with Down Syndrome
ras gene
Prostatic acid phosphatase
breast cancer incidence/mortality

14. Ligand - receptor interactions. Release of perforin and granzyme B.
prostate cancer incidence/mortality
erb - B2 gene
S-100
extrinsic apoptosis

15. Solid tissues with single blood supply. Heart - kidney and spleen.
Autoimmune (Hashimoto's - myasthenia gravis)
bcl -2 gene
Pale infarcts
blood vessels malignant tumor

16. Bacterial products (CLIK):C5a - LTB4 - IL-8 - Kallikrein
WT1 gene
benign epithelial tumor
Leukocyte extravasation: migration
smooth muscle malignant tumor

17. Sickle cell (altered shape) - polycythemia (too many) - CHF (unknown)
causes of decreased ESR
smooth muscle benign tumor
Napthalene (aniline) dyes target
c - myc gene

18. Leukemia - lymphoma
blood vessels benign tumor
blood cell malignant tumors
c - myc gene
Leukocyte extravasation: rolling

19. Cancer
Second - leading cause of death in the US
malignant epithelial tumor
Acute inflammatory mediators
paraneoplastic effects of thymoma - small cell lung carcinoma

20. Leiomyosarcoma
ras gene
Primary tumors that met to liver
smooth muscle malignant tumor
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms

21. Skin (SqCC) - liver (angiosarcoma)
iron poisoning
malignant mesenchyme tumor (general)
arsenic target
Irreversible - plasias

22. Retinoblastoma - osteosarcoma 13q tumor suppressor (blocks G1 to S phase progression)
Neoplasm associated with actinic keratosis
Where you see Psammoma bodies
Rb gene
prostate cancer incidence/mortality

23. Hepatocellular carcinoma
cirrosis (alcohol - hepB or C)
acanthosis nigricans (hyperpig and epidermal thickening)
blood vessels benign tumor
alpha - fetoprotein

24. Tumor marker: mets to bone - obstructive biliary disease - Paget's
fat malignant tumor
NF2 gene
acanthosis nigricans (hyperpig and epidermal thickening)
Alk - phos

25. Restoration of normal structure - granulation tissue (vascularized + fibrosis) - abscess (fibrosis + pus) - fistula or scarring (collagen).
S-100
breast cancer incidence/mortality
Where you see Psammoma bodies
Resolution of inflammation

26. Follicular and undifferentiated lymphomas anti - apoptotic molecule (oncogene)
CA-125
bcl -2 gene
smooth muscle malignant tumor
N- myc gene

27. Blood (leukemia)
blood vessels malignant tumor
Alkylating agents target
Chronic inflammatory mediators
blood vessels benign tumor

28. Sarcoma - papillary thyroid cancer
Leukocyte extravasation: tight binding
malignant >1 cell type tumor
radiation exposure
c - myc gene

29. Neutrophils (eos in the gut) - plus other granular leukocytes and antibodies.
NF1 gene
malignant epithelial tumor
p53 gene
Acute inflammatory mediators

30. Melanoma - basal cell carcinoma - and especially squamous cell carcinomas of the skin.
fat benign tumor
nitrosamines (smoked foods) target
Neoplasm associated with xeroderma pigmentosum (albinism)
Barrett's esophagus (chronic GI reflux)

31. ACTH or ACTH- like peptide
Neoplasm associated with xeroderma pigmentosum (albinism)
paraneoplastic effects of small cell lung carcinoma
Acute inflammatory mediators
radiation exposure

32. Mature teratoma in women
secondary amyloidosis (reactive systemic)
benign >1 cell type tumor
Free radical cell damage
ret gene

33. Esophagus - stomach
benign epithelial tumor
nitrosamines (smoked foods) target
Autoimmune (Hashimoto's - myasthenia gravis)
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms

34. Colorectal cancer (assoc with FAP) 5q tumor suppressor
APC gene
Red (hemorrhagic) infarcts
Pale infarcts
Leukocyte extravasation: migration

35. Most human cancers - specifically Li - Fraumeni syndrome 17p tumor suppressor (blocks G1 to S phase progression)
skeletal muscle benign tumor
N- myc gene
p53 gene
benign epithelial tumor

36. Tumor marker: Screen for prostate carcinoma. Can also be elevated in BPH and prostatitis.
lung cancer incidence/mortality
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants
APC gene
PSA

37. Neuroblastoma transcription factor (oncogene)
N- myc gene
benign >1 cell type tumor
Alkylating agents target
Neoplasm associated with Down Syndrome

38. Mature teratoma in men or malignant teratoma in M/F
DPC gene
erb - B2 gene
BRAC2 gene
malignant >1 cell type tumor

39. Prostate (blastic) - thyroid - testes - breast (lytic and blastic) - lung (lytic) - kidney (breast and prostate are most common)
Colon and rectal cancer incidence
prostate cancer incidence/mortality
Bombesin
Primary tumors that met to bone

40. Lipoma
aflatoxin target
Acute inflammatory mediators
NF1 gene
fat benign tumor

41. Lung (mesothelioma and bronchogenic carcinoma)
malignant mesenchyme tumor (general)
asbestos target
smooth muscle malignant tumor
erb - B2 gene

42. Rhabdomyosarcoma
skeletal muscle malignant tumor
Leukocyte extravasation: diapedesis
BRCA1 gene
NF2 gene

43. Osteoma
bone benign tumor
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants
Leading cause of death in the US
NF2 gene

44. Tumor marker: ovarian - malignant epithelial tumors.
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants
S-100
NF1 gene
CA-125

45. Lymphoma

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46. PECAM-1
ulcerative colitis
Leukocyte extravasation: diapedesis
p16 gene
iron poisoning

47. Leiomyoma
DPC gene
smooth muscle benign tumor
immunodeficiency states
Primary tumors that met to liver

48. 32%/13% male
aflatoxin target
Barrett's esophagus (chronic GI reflux)
DCC gene
prostate cancer incidence/mortality

49. 32%/18% female
L- myc gene
smooth muscle malignant tumor
breast cancer incidence/mortality
Leukocyte extravasation: migration

50. Neurofibromatosis type 2 22q tumor suppressor (key type 2=22)
Neoplasm associated with xeroderma pigmentosum (albinism)
intrinsic apoptosis
NF2 gene
Napthalene (aniline) dyes target