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First Aid Basics

Subjects : health-sciences, first-aid

Instructions:

Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can study here.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Squamous cell carcinoma of the esophagus
L- myc gene
Chronic inflammatory mediators
abl gene
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)

2. Liposarcoma
Primary tumors that met to brain
fat malignant tumor
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
WT1 gene

3. Erythropoietin
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
abl gene
erb - B2 gene
TRAP

4. Visceral malignancy (stomach - lung - breast - uterus)
acanthosis nigricans (hyperpig and epidermal thickening)
Leading cause of death in the US
asbestos target
CA-19-9

5. Tumor marker: ovarian - malignant epithelial tumors.
Where you see Psammoma bodies
Alkylating agents target
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.
CA-125

6. Colonic adenocarcinoma
Where you see Psammoma bodies
ulcerative colitis
arsenic target
NF1 gene

7. Bacterial products (CLIK):C5a - LTB4 - IL-8 - Kallikrein
Primary tumors that met to brain
Necrosis
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms
Leukocyte extravasation: migration

8. Tumor marker: tartrate - resistant acid phosphatase. Hairy cell leukemia (B- cell neoplasm)
NF1 gene
TRAP
Neoplasm associated with xeroderma pigmentosum (albinism)
arsenic target

9. Pancreatic cancer (Deleted in Pancreatic Cancer) 18q tumor suppressor
fat benign tumor
DPC gene
skeletal muscle malignant tumor
paraneoplastic effects of leukemias and lymphomas

10. Tumor marker: prostate carcinoma marker.
Paget's bone disease
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)
Prostatic acid phosphatase
L- myc gene

11. Breast and ovarian cancer 17q tumor suppressor (DNA repair protein)
Necrosis
malignant epithelial tumor
Leukocyte extravasation: rolling
BRCA1 gene

12. Skin (SqCC) - liver (angiosarcoma)
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants
breast cancer incidence/mortality
CA-125
arsenic target

13. Squamous cell carcinoma of skin
Second - leading cause of death in the US
Red (hemorrhagic) infarcts
CCl4 target
Neoplasm associated with actinic keratosis

14. Neuroblastoma transcription factor (oncogene)
cirrosis (alcohol - hepB or C)
APC gene
cigarette smoke target
N- myc gene

15. Neurofibromatosis type 2 22q tumor suppressor (key type 2=22)
NF2 gene
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms
smooth muscle malignant tumor
cigarette smoke target

16. Tumor marker: pancreatic adenocarcinoma
benign epithelial tumor
intrinsic apoptosis
CA-19-9
smooth muscle malignant tumor

17. Malignant lymphoma
smooth muscle benign tumor
Irreversible - plasias
immunodeficiency states
acanthosis nigricans (hyperpig and epidermal thickening)

18. Melanoma - basal cell carcinoma - and especially squamous cell carcinomas of the skin.
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms
granulomatous disease
blood vessels benign tumor
Neoplasm associated with xeroderma pigmentosum (albinism)

19. 32%/13% male
prostate cancer incidence/mortality
breast cancer incidence/mortality
iron poisoning
S-100

20. Hyperplasia - metaplasia - dysplasia
Red (hemorrhagic) infarcts
extrinsic apoptosis
Reversible - plasias
benign epithelial tumor

21. Colorectal cancer (assoc with FAP) 5q tumor suppressor
aflatoxin target
APC gene
skeletal muscle benign tumor
c - myc gene

22. PECAM-1
Leukocyte extravasation: diapedesis
asbestos target
paraneoplastic effects of small cell lung carcinoma
Leading cause of death in the US

23. CML tyrosine kinase (oncogene)
abl gene
Necrosis
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
Primary tumors that met to liver

24. Tumor marker: melanoma - neural tumors - astrocytomas
Primary tumors that met to brain
granulomatous disease
skeletal muscle benign tumor
S-100

25. During embryogenesis - hormone induction and atrophy. Increased mitochondrial permeability and cytochrome c release. Increase Bax (pro - apoptotic) - decreased Bcl -2 (anti - apopotic).
Prostatic acid phosphatase
Rb gene
intrinsic apoptosis
Free radical cell damage

26. Wilms' tumor 11p tumor suppressor
dysplastic nevus
nitrosamines (smoked foods) target
WT1 gene
ret gene

27. Macrophages and lymphocytes. Persistant destruction and repair.
Resolution of inflammation
Barrett's esophagus (chronic GI reflux)
Chronic inflammatory mediators
vinyl chloride target

28. Tumor marker: (Normal in fetus). Hepatocellular carcinomas. Nonseminomatous germ cell tumors of the testis.
alpha - fetoprotein
DCC gene
causes of decreased ESR
p16 gene

29. Leiomyosarcoma
Alkylating agents target
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)
smooth muscle malignant tumor
ulcerative colitis

30. Restoration of normal structure - granulation tissue (vascularized + fibrosis) - abscess (fibrosis + pus) - fistula or scarring (collagen).
immunodeficiency states
Resolution of inflammation
bone malignant tumor
asbestos target

31. Gastric adenocacinoma
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants
BRCA1 gene
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.
nitrosamines (smoked foods) target

32. Lung - breast - skin (melanoma) - kidney (renal cell carcinoma) - GI.50% brain tumors are from mets
nitrosamines (smoked foods) target
Primary tumors that met to brain
p16 gene
c - kit gene

33. Esophageal adenocarcinoma

34. AL
ras gene
CCl4 target
primary amyloidosis
CA-19-9

35. Hepatocellular carcinoma
cirrosis (alcohol - hepB or C)
lung cancer incidence/mortality
calcitonin
Rb gene

36. Antibodies to presynaptic Ca2+ channels at NM junction
Free radical cell damage
N- myc gene
paraneoplastic effects of thymoma - small cell lung carcinoma
CCl4 target

37. Tumor marker: carcinoembryonic Ag Very nonspecific
Reversible - plasias
benign >1 cell type tumor
L- myc gene
CEA

38. PTH- related peptide - TGF- beta - TNF - IL-1
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.
abl gene
Neoplasm associated with Down Syndrome
immunodeficiency states

39. Burkitt's lymphoma transcription factor (oncogene)
fat benign tumor
Reversible - plasias
BRAC2 gene
c - myc gene

40. Colon>stomach>pancreas>breast>lung (liver and lung are the most common places for mets)
Chronic inflammatory mediators
Primary tumors that met to liver
aflatoxin target
beta - hCG

41. Mature teratoma in women
beta - hCG
Leading cause of death in the US
benign >1 cell type tumor
PSA

42. Liver (angiosarcoma)
blood vessels malignant tumor
Free radical cell damage
vinyl chloride target
c - kit gene

43. Solid tissues with single blood supply. Heart - kidney and spleen.
Pale infarcts
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
DCC gene
lung cancer incidence/mortality

44. Rhabdomyoma
Colon and rectal cancer incidence
Autoimmune (Hashimoto's - myasthenia gravis)
skeletal muscle benign tumor
Neoplasm associated with Down Syndrome

45. Hyperuricemia (excess NA turnover)
paraneoplastic effects of leukemias and lymphomas
Reversible - plasias
malignant mesenchyme tumor (general)
Chronic inflammatory mediators

46. Female 13%/23% and rising Male 16%/33% (mortality has plateaued)
NF2 gene
Necrosis
lung cancer incidence/mortality
c - myc gene

47. Tumor marker: Hydatifiform moles - choriocarcinomas - gestational trophoblastic tumors.
smooth muscle benign tumor
asbestos target
beta - hCG
BRCA1 gene

48. Tumor marker: Screen for prostate carcinoma. Can also be elevated in BPH and prostatitis.
Leukocyte extravasation: migration
p53 gene
PSA
Primary tumors that met to bone

49. 32%/18% female
CA-125
breast cancer incidence/mortality
Barrett's esophagus (chronic GI reflux)
skeletal muscle malignant tumor

50. Liver (centrilobular necrosis - fatty change)
CCl4 target
Paget's bone disease
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)
TRAP