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First Aid Basics

Subjects : health-sciences, first-aid

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Breast and ovarian cancer 17q tumor suppressor (DNA repair protein)
CCl4 target
BRCA1 gene
CEA
Reversible - plasias

2. Tumor marker: pancreatic adenocarcinoma
paraneoplastic effects of small cell lung carcinoma and intracranial neoplasms
Neoplasm associated with xeroderma pigmentosum (albinism)
Leukocyte extravasation: diapedesis
CA-19-9

3. Tumor marker: carcinoembryonic Ag Very nonspecific
paraneoplastic effects of small cell lung carcinoma
Autoimmune (Hashimoto's - myasthenia gravis)
Neoplasm associated with xeroderma pigmentosum (albinism)
CEA

4. Sarcoma - papillary thyroid cancer
radiation exposure
c - kit gene
Alkylating agents target
Chronic inflammatory mediators

5. Restoration of normal structure - granulation tissue (vascularized + fibrosis) - abscess (fibrosis + pus) - fistula or scarring (collagen).
Free radical cell damage
TRAP
Resolution of inflammation
Primary tumors that met to liver

6. Liver (hepatocellular carcinoma)
paraneoplastic effects of thymoma - small cell lung carcinoma
extrinsic apoptosis
aflatoxin target
N- myc gene

7. GIST cytokine receptor (oncogene)
radiation exposure
c - kit gene
iron poisoning
Irreversible - plasias

8. Skin (SqCC) - liver (angiosarcoma)
Alk - phos
arsenic target
DPC gene
Free radical cell damage

9. Lung - liver - intestine or following reperfusion.
Leukocyte extravasation: tight binding
Red (hemorrhagic) infarcts
Prostatic acid phosphatase
paraneoplastic effects of leukemias and lymphomas

10. Hemangioma
acanthosis nigricans (hyperpig and epidermal thickening)
immunodeficiency states
Acute inflammatory mediators
blood vessels benign tumor

11. Adenocarcinoma - papillary carcinoma
dysplastic nevus
malignant epithelial tumor
Primary tumors that met to bone
Napthalene (aniline) dyes target

12. Burkitt's lymphoma transcription factor (oncogene)
CA-125
causes of increased ESR
blood cell malignant tumors
c - myc gene

13. Tumor marker: Hydatifiform moles - choriocarcinomas - gestational trophoblastic tumors.
beta - hCG
Leukocyte extravasation: rolling
aflatoxin target
smooth muscle benign tumor

14. Enzymes: catalase - superoxide dismutase - glutathione peroxidase.Vitamins: ACE Spontaneous decay
Free radical eliminators
alpha - fetoprotein
benign epithelial tumor
causes of decreased ESR

15. All - AML
paraneoplastic effects of small cell lung carcinoma
p16 gene
Leukocyte extravasation: tight binding
Neoplasm associated with Down Syndrome

16. Sickle cell (altered shape) - polycythemia (too many) - CHF (unknown)
Leukocyte extravasation: tight binding
Neoplasm associated with xeroderma pigmentosum (albinism)
causes of decreased ESR
Prostatic acid phosphatase

17. Tumor marker: neuroblastoma - lung and gastric cancer
Reversible - plasias
TRAP
Bombesin
dysplastic nevus

18. Angiosarcoma
CEA
Free radical eliminators
blood vessels malignant tumor
paraneoplastic effects of renal cell carcinoma - hemangioblastoma

19. Squamous cell carcinoma of skin
Acute inflammatory mediators
Neoplasm associated with actinic keratosis
erb - B2 gene
alpha - fetoprotein

20. Infections - inflammation - cancer - pregnancy - SLE
causes of increased ESR
fat benign tumor
fat malignant tumor
arsenic target

21. Caused by peroxidation of membrane lipids. Causes acute gastric bleeding and chronic metabolic acidosis and scarring.
TRAP
CA-125
Leukocyte extravasation: rolling
iron poisoning

22. 32%/13% male
Necrosis
radiation exposure
p16 gene
prostate cancer incidence/mortality

23. Female 13% Male 12%
WT1 gene
Colon and rectal cancer incidence
smooth muscle malignant tumor
Prostatic acid phosphatase

24. Antibodies to presynaptic Ca2+ channels at NM junction
secondary amyloidosis (reactive systemic)
paraneoplastic effects of thymoma - small cell lung carcinoma
TRAP
Necrosis

25. Most human cancers - specifically Li - Fraumeni syndrome 17p tumor suppressor (blocks G1 to S phase progression)
p53 gene
cigarette smoke target
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)
Leukocyte extravasation: rolling

26. Mature teratoma in men or malignant teratoma in M/F
malignant >1 cell type tumor
Pale infarcts
acanthosis nigricans (hyperpig and epidermal thickening)
granulomatous disease

27. Tumor marker: thyroid medullary carcinoma
extrinsic apoptosis
Autoimmune (Hashimoto's - myasthenia gravis)
calcitonin
lung cancer incidence/mortality

28. Cancer
breast cancer incidence/mortality
Second - leading cause of death in the US
L- myc gene
Where you see Psammoma bodies

29. Wilms' tumor 11p tumor suppressor
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)
Resolution of inflammation
Free radical cell damage
WT1 gene

30. Malignant lymphoma
Leukocyte extravasation: migration
immunodeficiency states
Neoplasm associated with actinic keratosis
TRAP

31. Vascular: ICAM-1 Leukocyte: LFA-1 (integrin)
smooth muscle benign tumor
fat malignant tumor
Leukocyte extravasation: tight binding
Alk - phos

32. Hyperuricemia (excess NA turnover)
Necrosis
benign epithelial tumor
paraneoplastic effects of leukemias and lymphomas
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)

33. Enzymatic degradation and protein denaturation due to exogenous injury. Inflammatory process where intracellular components extravasate.
Necrosis
Paget's bone disease
paraneoplastic effects of leukemias and lymphomas
L- myc gene

34. 32%/18% female
Leukocyte extravasation: tight binding
smooth muscle benign tumor
breast cancer incidence/mortality
Napthalene (aniline) dyes target

35. Vascular: E and P- selectin Leukocyte: Sialyl Lewis
fat malignant tumor
CA-19-9
beta - hCG
Leukocyte extravasation: rolling

36. Lung tumor transcription factor (oncogene)
PSA
blood vessels benign tumor
Where you see Psammoma bodies
L- myc gene

37. Tumor marker: tartrate - resistant acid phosphatase. Hairy cell leukemia (B- cell neoplasm)
Free radical eliminators
causes of decreased ESR
N- myc gene
TRAP

38. Visceral malignancy (stomach - lung - breast - uterus)
breast cancer incidence/mortality
Pale infarcts
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.
acanthosis nigricans (hyperpig and epidermal thickening)

39. Neutrophils (eos in the gut) - plus other granular leukocytes and antibodies.
Acute inflammatory mediators
WT1 gene
immunodeficiency states
skeletal muscle benign tumor

40. During embryogenesis - hormone induction and atrophy. Increased mitochondrial permeability and cytochrome c release. Increase Bax (pro - apoptotic) - decreased Bcl -2 (anti - apopotic).
intrinsic apoptosis
extrinsic apoptosis
Leukocyte extravasation: diapedesis
Reversible - plasias

41. Squamous cell carcinoma of the esophagus
Irreversible - plasias
beta - hCG
primary amyloidosis
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)

42. Colon>stomach>pancreas>breast>lung (liver and lung are the most common places for mets)
Primary tumors that met to liver
beta - hCG
blood vessels benign tumor
lung cancer incidence/mortality

43. Breast - ovarian and gastric carcinomas tyrosine kinase (oncogene)
c - kit gene
erb - B2 gene
secondary amyloidosis (reactive systemic)
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.

44. Neurofibromatosis type 1 17q tumor suppressor
iron poisoning
Rb gene
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
NF1 gene

45. Sarcoma
blood vessels benign tumor
ulcerative colitis
Resolution of inflammation
malignant mesenchyme tumor (general)

46. Adenoma - papilloma
benign epithelial tumor
smooth muscle malignant tumor
PSA
Second - leading cause of death in the US

47. Tumor marker: Screen for prostate carcinoma. Can also be elevated in BPH and prostatitis.
Napthalene (aniline) dyes target
iron poisoning
cirrosis (alcohol - hepB or C)
PSA

48. Breast cancer 13q tumor suppressor (DNA repair protein)
BRAC2 gene
ret gene
calcitonin
primary amyloidosis

49. Leukemia - lymphoma
AIDS
L- myc gene
blood cell malignant tumors
lung cancer incidence/mortality

50. Secondary osteosarcoma and fibrosarcoma

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First Aid Basics

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