Test your basic knowledge |

First Aid Basics

Subjects : health-sciences, first-aid

Instructions:

Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can study here.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Female 13%/23% and rising Male 16%/33% (mortality has plateaued)
Leading cause of death in the US
CEA
lung cancer incidence/mortality
DCC gene

2. PECAM-1
acanthosis nigricans (hyperpig and epidermal thickening)
Neoplasm associated with Down Syndrome
bone benign tumor
Leukocyte extravasation: diapedesis

3. Colon cancer (Deleted in Colon Cancer) 18q tumor suppressor
DCC gene
Paget's bone disease
Resolution of inflammation
skeletal muscle benign tumor

4. Aggressive malignant lymphomas (non - Hodgkin's) and Kaposi's sarcoma
DCC gene
Primary tumors that met to bone
bcl -2 gene
AIDS

5. Tumor marker: neuroblastoma - lung and gastric cancer
TRAP
Bombesin
bcl -2 gene
Free radical cell damage

6. Cancer
causes of increased ESR
skeletal muscle benign tumor
Second - leading cause of death in the US
erb - B2 gene

7. Colon carcinoma GTPase (oncogene)
ras gene
Leading cause of death in the US
benign epithelial tumor
Leukocyte extravasation: rolling

8. Wilms' tumor 11p tumor suppressor
WT1 gene
CA-19-9
Irreversible - plasias
APC gene

9. Tumor marker: (Normal in fetus). Hepatocellular carcinomas. Nonseminomatous germ cell tumors of the testis.
smooth muscle benign tumor
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.
alpha - fetoprotein
nitrosamines (smoked foods) target

10. Breast and ovarian cancer 17q tumor suppressor (DNA repair protein)
blood cell malignant tumors
BRCA1 gene
erb - B2 gene
AIDS

11. Neurofibromatosis type 1 17q tumor suppressor
Reversible - plasias
NF1 gene
blood vessels benign tumor
causes of decreased ESR

12. Hyperplasia - metaplasia - dysplasia
alpha - fetoprotein
calcitonin
Reversible - plasias
Where you see Psammoma bodies

13. Hemangioma
Second - leading cause of death in the US
blood vessels benign tumor
smooth muscle malignant tumor
Reversible - plasias

14. Enzymes: catalase - superoxide dismutase - glutathione peroxidase.Vitamins: ACE Spontaneous decay
Free radical eliminators
BRCA1 gene
Pale infarcts
PSA

15. Astrocytoma - angiomyolipoma - cardiac rhabdomyoma
CEA
Prostatic acid phosphatase
dysplastic nevus
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)

16. 32%/18% female
breast cancer incidence/mortality
BRAC2 gene
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.

17. During embryogenesis - hormone induction and atrophy. Increased mitochondrial permeability and cytochrome c release. Increase Bax (pro - apoptotic) - decreased Bcl -2 (anti - apopotic).
intrinsic apoptosis
calcitonin
c - myc gene
bcl -2 gene

18. Follicular and undifferentiated lymphomas anti - apoptotic molecule (oncogene)
p16 gene
bcl -2 gene
paraneoplastic effects of thymoma - small cell lung carcinoma
Chronic inflammatory mediators

19. Retinoblastoma - osteosarcoma 13q tumor suppressor (blocks G1 to S phase progression)
Rb gene
acanthosis nigricans (hyperpig and epidermal thickening)
AIDS
blood vessels benign tumor

20. Membrane lipid peroxidation - protein modification and DNA breakage.
Bombesin
paraneoplastic effects of SqC lung carcinoma - renal cell carcinoma and breast carcinoma.
Free radical cell damage
bone malignant tumor

21. Squamous cell carcinoma of the esophagus
skeletal muscle benign tumor
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)
Reversible - plasias
malignant >1 cell type tumor

22. Tumor marker: carcinoembryonic Ag Very nonspecific
causes of decreased ESR
Leukocyte extravasation: diapedesis
DPC gene
CEA

23. Tumor marker: tartrate - resistant acid phosphatase. Hairy cell leukemia (B- cell neoplasm)
TRAP
Red (hemorrhagic) infarcts
benign >1 cell type tumor
BRCA1 gene

24. CML tyrosine kinase (oncogene)
Bombesin
aflatoxin target
vinyl chloride target
abl gene

25. Larynx (SqCC) - lung (SqCC and SCC) - kidney (renal cell carcinoma) - bladder (transitional cell carcinoma)
Neoplasm associated with Down Syndrome
cigarette smoke target
causes of decreased ESR
nitrosamines (smoked foods) target

26. Neurofibromatosis type 2 22q tumor suppressor (key type 2=22)
benign epithelial tumor
Rb gene
blood vessels malignant tumor
NF2 gene

27. Caused by peroxidation of membrane lipids. Causes acute gastric bleeding and chronic metabolic acidosis and scarring.
Leukocyte extravasation: rolling
Resolution of inflammation
cigarette smoke target
iron poisoning

28. Breast cancer 13q tumor suppressor (DNA repair protein)
Leukocyte extravasation: migration
Barrett's esophagus (chronic GI reflux)
ulcerative colitis
BRAC2 gene

29. Adenoma - papilloma
Alk - phos
benign epithelial tumor
Neoplasm associated with actinic keratosis
skeletal muscle malignant tumor

30. Visceral malignancy (stomach - lung - breast - uterus)
Alk - phos
acanthosis nigricans (hyperpig and epidermal thickening)
Chronic inflammatory mediators
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)

31. Adenocarcinoma - papillary carcinoma
dysplastic nevus
BRAC2 gene
malignant epithelial tumor
Free radical cell damage

32. Bacterial products (CLIK):C5a - LTB4 - IL-8 - Kallikrein
Prostatic acid phosphatase
Red (hemorrhagic) infarcts
Neoplasm associated with actinic keratosis
Leukocyte extravasation: migration

33. Squamous cell carcinoma of skin
Necrosis
skeletal muscle benign tumor
Bombesin
Neoplasm associated with actinic keratosis

34. Mature teratoma in women
Napthalene (aniline) dyes target
Rb gene
lung cancer incidence/mortality
benign >1 cell type tumor

35. Vascular: ICAM-1 Leukocyte: LFA-1 (integrin)
Leukocyte extravasation: tight binding
Rb gene
Barrett's esophagus (chronic GI reflux)
abl gene

36. Anaplasia - neoplasia - desmoplasia (fibrous tissue formation in response to neoplasm)
CA-19-9
paraneoplastic effects of small cell lung carcinoma
CCl4 target
Irreversible - plasias

37. Rhabdomyoma
skeletal muscle benign tumor
Reversible - plasias
Primary tumors that met to brain
primary amyloidosis

38. Sarcoma - papillary thyroid cancer
Colon and rectal cancer incidence
Leukocyte extravasation: rolling
radiation exposure
alpha - fetoprotein

39. Tumor marker: mets to bone - obstructive biliary disease - Paget's
NF1 gene
Alk - phos
Where you see Psammoma bodies
granulomatous disease

40. Osteoma
blood vessels malignant tumor
Neoplasm associated with actinic keratosis
p16 gene
bone benign tumor

41. Osteosarcoma
malignant epithelial tumor
calcitonin
Colon and rectal cancer incidence
bone malignant tumor

42. Neutrophils (eos in the gut) - plus other granular leukocytes and antibodies.
BRAC2 gene
CCl4 target
Acute inflammatory mediators
Neoplasm associated with xeroderma pigmentosum (albinism)

43. Leiomyosarcoma
fat malignant tumor
secondary amyloidosis (reactive systemic)
smooth muscle malignant tumor
aflatoxin target

44. Antibodies to presynaptic Ca2+ channels at NM junction
Plummer - Vinson syndrome (atrophic glossitis - esophageal webs - anemia)
Neoplasm associated with actinic keratosis
paraneoplastic effects of thymoma - small cell lung carcinoma
Autoimmune (Hashimoto's - myasthenia gravis)

45. Erythropoietin
fat benign tumor
benign >1 cell type tumor
paraneoplastic effects of renal cell carcinoma - hemangioblastoma
CEA

46. Esophagus - stomach
nitrosamines (smoked foods) target
blood vessels malignant tumor
L- myc gene
malignant >1 cell type tumor

47. Tumor marker: thyroid medullary carcinoma
calcitonin
iron poisoning
cigarette smoke target
Neoplasm associated with chronic atrophic gastritis - pernicious anemia - postsurgical gastric remants

48. Ligand - receptor interactions. Release of perforin and granzyme B.
Leukocyte extravasation: diapedesis
prostate cancer incidence/mortality
extrinsic apoptosis
Neoplasm associated with tuberous sclerosis (facial angiofibroma - seizures - mental retardation)

49. Vascular: E and P- selectin Leukocyte: Sialyl Lewis
Leukocyte extravasation: rolling
ulcerative colitis
alpha - fetoprotein
c - kit gene

50. Rhabdomyosarcoma
acanthosis nigricans (hyperpig and epidermal thickening)
aflatoxin target
NF2 gene
skeletal muscle malignant tumor