Test your basic knowledge |

GRE Chromosomal And Molecular Basis Of Inheritance

Subjects : gre, science, biology
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Offspring that have new combinations of their parent'S phenotypes. When 50% of offspring are recombinants - geneticists say that there is a 50% frequency of recombination and is observed for any two genes that are located on different chromosomes.






2. Occurs when a mismatched nucleotide evades proofreading by DNA polymerase or arise after DNA synthesis is completed.






3. Genes located on the same chromosome that tend to be inherited together in genetic crosses. These results deviate from those expected from Mendel'S law of independent assortment.






4. An enzyme that joins the sugar-phosphate backbones of the Okazaki fragments - forming a single new DNA strand.






5. A gene located on either sex chromosome. In humans - the term has historically referred specifically to a gene on the X chromosome so fathers pass sex-linked alleles to all of their daughters and none of their sons while mothers can pass sex-linked a






6. A way of expressing distances between genes - defining one map unit as equivalent to a 1% recombination frequency.






7. The general term for a chromosomal alteration in which an organism has more than two complete chromosome sets. There are more specific terms like triploidy (3n) and tetraploidy (4n) indicating 3 or 4 chromosomal sets - respectively.






8. Can be distinguished from Watson and Crick'S semiconservative model in which the parent molecule somehow re-forms after the process of replication. Proved incorrect and support came out for the semiconservative model.






9. The ___________ two genes are - the higher the probability that a crossover will occur between them and therefore the higher the recombination frequency. This process can occasionally break the physical connection between genes on the same chromosome






10. Traits that are alternatives to the wild type because they are due to alleles assumed to have arisen as changes - or mutations - in the wild-type allele.






11. An enzyme that catalyzes the lengthening of telomeres in eukaryotic germ cells - thus restoring their original length and compensating for the shortening that occurs during DNA replication. Made possible by the presence in the telomerase of a short






12. A type of change in chromosome structure as a result of some sort of chromosomal breakage. Occurs when a chromosomal fragment lacking a centromere is lost. The affected chromosome is then missing certain genes.






13. The mammalian system for determining sex. The sex of the offspring depends on whether the sperm cell contains an X chromosome or a Y.






14. Y-shaped region at the end of a replication bubble where the new strands of DNA are elongating.






15. A occasional mishap that may occur during meiosis in which the members of a pair of chromosomes do not move apart properly during meiosis I or sister chromatids fail to separate during meiosis II.






16. The system for determining sex in grasshoppers - cockroaches - and some other insects. In these insects - there is only one type of chromosome - the X. Females are XX and males are XO. Sex of the offspring is determined by whether the sperm cell cont






17. A type of change in chromosome structure as a result of some sort of chromosomal breakage. Occurs when a segment within a chromosome reverses.






18. The system for determining sex in most species of bees and ants. There are no sex chromosomes in these species - Females develop from fertilized ova and are thus diploid. Males - however - develop from unfertilized ova and are haploid; they have no f






19. A method that maps chromosomes and locates genes with respect to chromosomal features - such as stained bands - that can be seen in the microscope. Ultimately show the physical distances between gene loci in DNA nucleotides.






20. Adenine doubles bonds thymine and guanine triple bonds cytosine.






21. Alleles of genes on nonhomologous chromosome assort independently during gamete formation.






22. The most common type of translocation. A type of change in chromosome structure as a result of some sort of chromosomal breakage. In this - nonhomologous chromosome exchange fragments.






23. Phenotypically female but are sterile because their sex organs do not mature. When provided with estrogen replacement therapy - girls with Turners develop secondary sex characteristics.






24. Traits that depend on which parent passed along the alleles for those traits. An exception to the display of Mendelian inheritance.






25. Genes located in organelles in the cytoplasm. Mitochondria and plastids contain small circular DNA molecules that carry genes coding for proteins and RNA and do not display Mendelian inheritance. For example - almost all the mitochondria come from th






26. A chromosome is present in triplicate in an aneuploid cell.






27. Special site on a DNA molecule which replication begins. Indicated by a specific sequence of nucleotides.






28. 1. deletion 2. duplication 3. inversion 4. translocation






29. DNA repair that involves cleaving by nuclease and gap refilling by DNA polymerase and ligase.






30. Or phages. Viruses that infect bacteria.






31. One of the first imprinted genes to be identified. Although this growth factor is required for normal prenatal growth - only the paternal allele is expressed.






32. Helps in repairing and proofreading DNA. An enzyme that cuts out a segment of the strand of DNA containing damage - creating a gap which is filled in with nucleotides properly paired with the nucleotides in the undamaged strand by DNA polymerase and






33. A result of nondisjuction of sex chromosomes. Females are healthy and cannot be distinguished phenotypically from other females.






34. Each nucleotide added to a growing DNA strand is a nucleoside triphosphate - which is a sugar and a base with three phosphate groups. The triphosphate monomers used are chemically reactive - partly because their triphosphate tails have an unstable cl






35. An enzyme that untwists the double helix at the replication forks - separating the two parental strands and making them available as template strands. This untwisting causes tighter twisting and strain ahead of the replication forks which is relieved






36. A change in genotype and phenotype due to the assimilation of external DNA by a cell.






37. The short initial nucleotide chain put in place before DNA polymerase begins synthesizing in the 5' to 3' direction. May consist of either DNA or RNA. In initiating the replication of cellular DNA - the primer is a short stretch of RNA with an availa






38. The sex-determining region of Y. The gene on the Y chromosome required for the development of testes. In the absence of SRY - the gonads develop into ovaries. SRY is simply the trigger and other genes on the Y chromosome are required for normal testi






39. A type of change in chromosome structure as a result of some sort of chromosomal breakage. Occurs when a chromosomal fragment repeats a segment. In some cases - if meiosis is in progress - a deleted fragment may become as an extra segment to a sister






40. The most common phenotype in a natural population.






41. The various proteins that participate in DNA replication actually form a single large complex since many of the protein-protein interactions actually facilitate the efficiency of the machine as a whole.

Warning: Invalid argument supplied for foreach() in /var/www/html/basicversity.com/show_quiz.php on line 183


42. The segments of the lagging strand that get added to the template strand. The segments get joined together by DNA ligase.






43. Predicted by Watson and Crick. Suggests that when a double helix replicates - each of the two daughter molecules will have one old strand - derived from the parent molecule - and one newly made strand.






44. The system for determining sex in birds - some fishes - and some insects. The sex chromosome present in the ovum determines the sex of offspring. The sex chromosomes are designated Z and W. Females are ZW and males are ZZ.






45. Disorder caused by structurally altered chromosomes - specifically a deletion in chromosome 5. A child born with this deletion is mentally retarded - has a small head with unusual facial features - and has a cry that sounds like the mewing of a cat.






46. According to this theory - Mendelian genes have specific loci (positions) on chromosomes - and it is the chromosomes that undergo segregation and independent assortment.






47. A human sex-linked disorder. A disease characterized by progressive weakening of the muscles and loss of coordination. Affected individuals rarely live past their early 20s. A result of the absence of a key muscle protein called dystrophin.






48. The new strand of DNA moving in the direction away from the replication fork. Synthesized as a series of segments in contrast to the leading strand that elongates continuously.






49. A molecule that binds unpaired DNA strands - after its been separated by helicase - and stabilizes them until they serve as templates for the synthesis of new complementary strands.






50. A type of change in chromosome structure as a result of some sort of chromosomal breakage. Occurs when a chromosomal fragment breaks and joins a nonhomologous chromosome.