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Test your basic knowledge |
MCAT Prep - 2
Start Test
Study First
Subjects
:
mcat
,
science
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Between meals most fats appear in blood as
Lipoproteins; albumin carries free fatty acids when fat is mobilized from adipose tissue - etc
Presence of fat - prot in duodenum causes release of **gastric inhibitory peptide**; result is slower stomach contraction; slower emptying into duod thru pyloric sphincter (slower chyme secretion); more time to properly digest - absorb nutrients
It targets liver conc of prothrombin - fibrinogen etc
Facilitated diffusion from hi to lo conc
2. FLAT PG: hGH aka somatotropin
Peptide; stims growth of nearly all cell of body; all other anterior pituitary horms have specific targets; upregulates anabolic pathways; use of fat for energy goes up (fat - burning); increases AA transport across cell membrane (nutrient uptake)
Salivary amylase; both hydrolyze glycosidic linkages
At metaphase II of meiosis II (halted during reductional division); if fertilized - process continues toward haploid gamete
Spinal cord ventral horns; somatic motor neurons use acetylcholine for NTs (voluntary)
3. FLAT PG: LH
Ganglion
Peptide; responsible for luteal surge (driven in part by LH-->testosterone -->estradiol -->LH positive feedback); results in ovulation (follicle bursting) - releasing egg into fallopian tube/oviduct
Chyme (by combined activity of exocrine glands)
Processes: axons - dendrites
4. Where does fertilization occur
Fallopian tubes
Polysaccharides w/proteoglycans attached = glycosaminoglycans; often give pliability
Posterior pituitary hormone; acts on uterus - mammary glands; causes uterine contractions - milk ejection
TAGS--->FFAs; remember that FFAs are broken down for energy in mito matrix by beta - oxidation
5. liver and blood glucose...
Liver is the control center for blood glucose; is fed by portal vein from sm intest
Facilitated diffusion: no symport w/ secondary transport
Mouth - esophagus - stomach - duodenum - jejunum - ileum - ascending colon - transverse colon - descending colon - sigmoid colon - rectum - anus
(haploid organism) many fungi and protozoa; individuals are typically haploid; fertilization may occur with immediate meiosis back to haploid state
6. Meiosis I Anaphase I
Prophase I: crossing over occurs; nuclear envelope is absorbed into ER; chromosomes condense)
Glucose = aldose fructose = ketose
Oxidizes macromolecules; breaks down very long - chain FAs by beta - oxidation; products (acetyl - CoA) are shuttled to mitochondrion for citric acid cycle
Homologous chromosomes separate - migrate towards opposite poles/centrioles
7. gametic life cycle
Spike in estrogen - LH levels; secondary follicle bursts - releases into body cavity - swept along by fimbriae
The crypts of Lieberkuhn: sm intestine pH is not right; brush border enzs won't work right
Small amounts of hydrolyzed phospholipids and cholesterol: like other fat mols these can diffuse thru enterocyte membrane
(diploid organism) humans are part of gametic life cycle ie produce gametes; diploid germ - line stem cells undergo meiosis to form haploid gametes
8. what happens to bile secretions
***starting with adipose tiss: FFAs are transported in the blood by albumin (major component of blood plasma); one albumin typically carries three fatty acid molecules but can hold up to 30 FAs
Needs time for bile - lipase - micelle migration - enterocyte uptake
Testes>Semeniferous tubules>Sertoli cells; feedback on AP FSH production
Mostly reabsorbed to liver
9. What does peptic refer to in general
Fallopian tubes
Digestion
Urine enters kidneys via artery - to arteriole - capillary bed - glomerulus - Bowman's capsule - proximal tubule - loop of henle (concentrates medulla) - distal tubule - collecting tubule - collecting duct (renal pyramids) - renal calyx - renal pelvi
Fat synthesis; carbs stored as free fatty acids - esterified to TAGs (requires small amount of E)
10. What is secreted into filtrate by cells of the proximal tubule?
Liver breaks down glycogen (glycogenolysis); at hi blood sugar it builds up glycogen (glycogenesis)
Drugs - toxins - bile pigments (color the urine) - uric acid - antibiotics
REABSORPTION: draws off water and ions - increases osmolarity of the medulla while slightly lowering osmolarity of the filtrate -->medulla must have hi osmolarity in order to concentrate urine at collecting duct (final step in nephron)
Sorts - modifies - concentrates proteins from the ER
11. gradual increase in FSH typical of primary follicle development;
'Microvilli function as the **primary surface of nutrient absorption in the gastrointestinal tract**. Because of this vital function - the microvillar membrane is packed with enzymes that aid in the breakdown of complex nutrients into simpler compoun
Glucose
Adrenal gland -- AC: steroids (cortisol - aldosterone); AM: catecholamines (epi - norepi); Islets of langerhans: peptides (insulin/glucagon) ANTAGONISTS: calcitonin (thyroid - peptide lowers Ca in blood); parathyroid hormone - peptide - vitamin D pat
Secondary follicle: Theca cells differentiate from interstitial tissue - surround follicle - secrete testosterone when stimd by LH (compare to Leydig cells)
12. Tight junctions
Steroid; target tissue is distal convoluted tubule of nephron and collecting duct; increases blood mineral concentration; potassium - protons secreted (blood pH increases); sodium - chloride reabsorbed (BP increases)
Determination is a pre - programmed fate - differentiation is the actual materialization of that fate
Form barrier to extracellular fluid
Tight regulation of parietal cells needed b/c gastric acid secretion is E- intensive; parietal cells are hi in mitochons
13. What is somatostatin
***nicotinic is ionotropic; muscarinic is GPCR
Increases blood Calcium
Below hypothalamus
Secreted by delta cells of Islets of langerhans; inhibits insulin and glucagon; slows digestion
14. parathyroid hormone
AAs can be burned for energy or converted to fat for storage
Contains hydrolytic enzymes; thus - digests endocytosed substances; derived from golgi
Increases blood Calcium
Two perpendicular semicircular canals involved in balance - equilibrium
15. fat digestion is time - intensive
Lower blood pH
Needs time for bile - lipase - micelle migration - enterocyte uptake
Oxidizes macromolecules; breaks down very long - chain FAs by beta - oxidation; products (acetyl - CoA) are shuttled to mitochondrion for citric acid cycle
Fovea (highest amount of cones)
16. SYMP neurons originate in= PARA neurons originate in=
Nuclear envelope reassembled in daughter cells; cytokinesis occurs; nucleoli reappear (site of rRNA synthesis)
Inner lining of circulatory system
SYMP: spinal cord --->paravetebral ganglion PARA: spinal cord - brain; cell processes --->ganglion near effector organ (preganglionic neurons) extend outside of spinal cord to synapse at ganglia - go on along postganglionic neurons
Prophase II: no crossing over b/c there are no homologous chromosomes; nuclear envelope dissolves Metaphase II: chromosomes line up at metaphase plate Anaphase II: sister chromatids separate - migrate to opp poles Telophase II: nuclear envelope reap
17. Gastrin from G cells stims parietal cells...
At metaphase II of meiosis II (halted during reductional division); if fertilized - process continues toward haploid gamete
Tight regulation of parietal cells needed b/c gastric acid secretion is E- intensive; parietal cells are hi in mitochons
Posterior pituitary hormone; acts on uterus - mammary glands; causes uterine contractions - milk ejection
Which is why lactase - maltase - dextrinase - sucrase are on brush border
18. thyroid hormones: Not All One Kind of HORM
Calcitonin (peptide; lowers blood Ca); T3/T4 (tyrosine - derived; increase basal metabolic rate); T4= thyroxine
Liver is the control center for blood glucose; is fed by portal vein from sm intest
In liver (RBC recycling of heme); stored in gall bladder; released via cystic duct to common bile duct (shared w/liver); common bile duct joins up with panc duct...everything feeds into the sm intest at the ampulla of vater**
After 4 day+ - morula cells have formed fluid - filled ball (blastocyst); this implants in uterus at day 5-7; blastocyst is made up of EMBRYONIC STEM Cells; once implanted w/blastocyst - female is pregnant
19. exocrine types
Sudiferous (sweat) - sebaceous - digestive (bile - pancreatic enzs) - mucosal
- parietal cells (**oxyntic= hi oxygen consumption - hi E??): have hi conc mito; need lots of energy to create proton gradient; thus - responsible for extremely harsh pH conditions in stom; denaturing conditions - chief cells (peptic): synthesize pep
On to the distal tubule where sodium - calcium are reabsorbed - protons - bicarbonate - potassium are secreted via membrane transport proteins
Peptide; stims growth of nearly all cell of body; all other anterior pituitary horms have specific targets; upregulates anabolic pathways; use of fat for energy goes up (fat - burning); increases AA transport across cell membrane (nutrient uptake)
20. small intestine=
Trypsin(- ogen; activates other panc enzymes after it is activated by enterokinase of sm intest); chymotrypsin - amylase - lipase
All carbs absorbed at enterocytes are carried to liver by portal vein
Comes into play in the large intestine - where vitamin b12 is absorbed w/help of E. coli; thus; must travel thru bloodstream to large intestine
Duodenum (wraps around pancreas; most digestion occurs here) - jejunum (pH 7-9; 2m) - ileum
21. in mammals - gastrulation involves formation of the
Primitive streak - which consists of cells of the MESODERM ****
AAs can be burned for energy or converted to fat for storage
Liposome has phospholipid bilayer
Four 23 N daughter cells are formed from one 46 2N mother (germ - line) cell; four haploid gametes
22. E storage per unit mass
Carbohydrates are highly hydrated: one water mol per carbon mol - fats are anhydrous: contain more reduced carbons per unit mass - altogether fats contain 6X energy per unit mass
Receive signals from receptor cell w/ ability to interact with its environment; 99% sensory input is discarded
Drugs - toxins - bile pigments (color the urine) - uric acid - antibiotics
Peak at 1-2hr after meal; chylomicrons themselves have half - life of about 1hr after formation in enterocytes
23. when cells hit their limit for prot storage...
Secondary oocyte (stim'd by LH stimulation of theca cells causing release of testosterone - converted to estradiol; eventually brings about luteal surge -->EQUATIONAL DIVISION-->ovum released during ovulation into fallopian tube; burst follicle becom
AAs can be burned for energy or converted to fat for storage
visual (rhodopsin is receptor - derived from Vit A; conformation change occurs with photon to hyperpolarize rod cells; cone cells use photopsin for receptor) - olfactory - mood (NTs targeted by antidepressants - antipsychotics - etc; GABA is inhibit
Liver Functions pt. 2 - Carb metabolism: blood is sent straight to liver from sm intest thru portal vein; liver is control center for blood glucose; _______________ - fat metabolism: oxidizes fat for energy by beta - oxidation - forms most lipoprotei
24. physiology of gall bladder - liver and pancreatic secretions
(diploid and haploid individuals = ALTERNATION of GENERATIONS) a fusion of gametic and zygotic life cycles
Maintains hi estrogen levels; body does not recognize luteal surge - ovulation does not occur; hi progesterone can lessen shedding by thickening the uterine lining
Combined via conjunction of pancreatic duct and common bile duct; common bile duct originates at **cystic duct where gall bladder and liver secretions combine ..cystic duct+common bile duct+pancreatic duct --->into duodenum
Sudiferous (sweat) - sebaceous - digestive (bile - pancreatic enzs) - mucosal
25. keep in mind that enterocyte is like a regular euk cell
Combined via conjunction of pancreatic duct and common bile duct; common bile duct originates at **cystic duct where gall bladder and liver secretions combine ..cystic duct+common bile duct+pancreatic duct --->into duodenum
Needs time for bile - lipase - micelle migration - enterocyte uptake
Has memb - bound organelles - etc...
SYMP: spinal cord --->paravetebral ganglion PARA: spinal cord - brain; cell processes --->ganglion near effector organ (preganglionic neurons) extend outside of spinal cord to synapse at ganglia - go on along postganglionic neurons
26. FSH - LH - HCG - inhibin are...
Drugs - toxins - bile pigments (color the urine) - uric acid - antibiotics
Peptides
From lumenal (apical) to enterocyte to basolateral side of epithelial tissue
Renal pyramids --->renal calyx-->renal pelvis -->ureter -->urethra
27. pancreatic enzymes are zymogens
23 N; 23 chromosomes and haploid (no homologous chromosomes); each chromosome has two sister chromatids Male: primary spermatocyte -->REDUCTIONAL DIVISION (first stim'd at puberty by GnRH - LH-->secondary spermatocyte Female: primary oocyte (arreste
'Increased absorptive area is useful because digested nutrients (including sugars and amino acids) pass into the villi through diffusion - which is effective only at short distances. In other words - **increased surface area (in contact with the flui
Interstitial fluid (eg prostaglandins - cytokines)
Trypsinogen is activated by enterokinase in the brush border; in turn - it activates other enzymes
28. Induction affects...
Cancer; apop can be programmed cell death; mitochon can play important role in apop
Direction of differentiation
Water flows from the tubule - concentrating the filtrate - raising BP
Bacterial flagellin: hollow filament (not microtub); euk: 9+2 microtubule w/dynein bridges
29. Which fats are not absorbed like this
Many modern drugs are ligands for GPCRs
Fallopian tubes
Smaller - more water soluble short - chain FAs go directly to bloodstream at villi capillaries
Going up - water - impermeable: salt is actively pumped out - filtrate osmolarity goes down as salt leaves
30. After meiosis II - Male
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31. these transport proteins - when concs are high enough...
Abdominal cavity - which is coated in serous fluid
Can be saturated; conc of a solute is called the transport maximum --->excess goes into urine
Testosterone and estradiol
FAT=9 cal per gram Carbs=4.5 cal per gram - Prot=4 cal per gram - these seem to be for anhydrous forms
32. main point of fat transport...
All carbs absorbed at enterocytes are carried to liver by portal vein
Fructose is a structural isomer of glucose
Fat is insoluble in blood and requires a carrier like lipoproteins (vLDL...HDL) or albumins; ...vLDL has hi triglycerides - hi cholesterol
Stomach - sm intest - spleen - pancreas from the hepatic portal vein...all blood that passes thru liver go thru flattened spaces called the ***hepatic sinusoids -->hepatic vein --->vena cava
33. Sensory neuron cell bodies vs. somatic motor cell bodies
Somatic sensory = dorsal root ganglia (outside spinal cord); somatic effector = ventral horns of spinal cord
AAs can be burned for energy or converted to fat for storage
Food is digested from mouth to stomach (denaturation by gastric acid - digested by pepsin) to duodenum (more digestion); then absorption occurs in jejunum and ileum
= catecholamines; fight/flight; vasoconstrictors of internal organs - skin; vasodilators of skel musc; also considered stress hormones; epinephrine - norepinephrine
34. peroxisome is derived from this
Liposome has phospholipid bilayer
via symport - secondary transport (ie by pre - established - ATP- intensive) with Na gradient into enterocyte......with no Na gradient (ie without ATP) carbohydrate monomers could not be transported in
ER
**NO*** lipase digests fat; no bonds broken by bile; only opens up more SA for lipase
35. Where does the bolus go after mouth chews food
Glucocorticoid (cortisol); mineralocorticoid (aldosterone)
Moves down thru esophageal sphincter
Glucose and ketone bodies (not from glycogen stores)
***nicotinic is ionotropic; muscarinic is GPCR
36. Difference between euk and prok flagella
Bacterial flagellin: hollow filament (not microtub); euk: 9+2 microtubule w/dynein bridges
Needs time for bile - lipase - micelle migration - enterocyte uptake
Prophase I: crossing over occurs; nuclear envelope is absorbed into ER; chromosomes condense)
Salivary amylase; both hydrolyze glycosidic linkages
37. Ovum development is halted At what stage until fertilization...
Collection of cell bodies; cell processes project out from both ends of ganglion; synapses with interneuron in spinal cord on one end and sensory receptor on other
Salivary amylase (weak); sm intest amylase (breaks down large polysaccharides)
5
At metaphase II of meiosis II (halted during reductional division); if fertilized - process continues toward haploid gamete
38. 'Cell bodies of somatic motor neurons are located in....'
Outermost layer of blood vessel
Spinal cord ventral horns; somatic motor neurons use acetylcholine for NTs (voluntary)
- enterocytes w/ *microvilli brush border*: membrane - bound digestive enzymes for carbs - fats - nucleic acids - goblet cells: secrete mucous - Deep between villi are the intestinal exocrine glands - the crypts of Lieberkuhn - which secrete pH 7.6 i
At the first capillary bed of the nephron called the glomerulus which is encased by ***Bowman's capsule
39. parathyroid hormones
Parathyroid hormone (peptide; increases blood Ca); thus - might increase osteoclast/decrease osteoblast activity
Ganglion
Trypsinogen is activated by enterokinase in the brush border; in turn - it activates other enzymes
Eukaryotes
40. Four tissues
Ketone bodies; thus excessive reliance on fat for energy (eg low carb diets) results in ketosis; blood acidity increases
Nervous - muscle - epithelial (defines inner/outer) - connective (extensive matrices)
Gall bladder - pancreatic secretions increase - arrive via ampulla of vater (duct glands); insulin secretion increases (fed state; ductless glands)
Smaller - more water soluble short - chain FAs go directly to bloodstream at villi capillaries
41. bile + fat forms
An endogenous morphine
Creates one ovum (23 N) and three polar bodies
- enterocytes w/ *microvilli brush border*: membrane - bound digestive enzymes for carbs - fats - nucleic acids - goblet cells: secrete mucous - Deep between villi are the intestinal exocrine glands - the crypts of Lieberkuhn - which secrete pH 7.6 i
Micelles; micelles transport lipase products to enterocytes for absorption at brush border
42. What Changes - Doesn't Change as a result of movement of molecules across membranes in the proximal tubule
Trypsinogen is activated by enterokinase in the brush border; in turn - it activates other enzymes
23 N; 23 chromosomes and haploid (no homologous chromosomes); each chromosome has two sister chromatids Male: primary spermatocyte -->REDUCTIONAL DIVISION (first stim'd at puberty by GnRH - LH-->secondary spermatocyte Female: primary oocyte (arreste
Stomach - sm intest - spleen - pancreas from the hepatic portal vein...all blood that passes thru liver go thru flattened spaces called the ***hepatic sinusoids -->hepatic vein --->vena cava
Changes: volume of filtrate does not change: osmolarity of filtrate --->reabsorbed ions like sodium carry water across membrane
43. Where does the juxtaglomerular apparatus come into play...renin --->inc angiotensins -->inc aldosterone - ups BP
Monitors filtrate pressure in the distal tubule; has specialized cells (granular cells) that secrete an enzyme (**renin); renin initiates regulatory cascade that produces angiotensin I - II - III that stim adrenal cortex to secrete aldosterone... ...
AAs can be burned for energy or converted to fat for storage
Work together to emulsify fats: bile works as a detergent to increase SA of the fat; increased SA gives more substrate to lipase for digestion
Peripheral nervous sys
44. Does bile digest fat?
**NO*** lipase digests fat; no bonds broken by bile; only opens up more SA for lipase
vitreous humor - retina - fovea
Contain capillary network - lymph vessels (lacteals)
Low because AAs are immediately used in translation
45. Morula (...totipotent)
Zygote (morula) composed of eight or more cells; All cells at this stage are TOTipOTENT STEM Cells: do not grow - form by cleavage
Follicular (proliferative)= 8d - Luteal (post - ovulation; corpus luteum secretions)= 13d - Menstruation (shed uterine lining if no implantation)= 5
From lumenal (apical) to enterocyte to basolateral side of epithelial tissue
Abdominal cavity - which is coated in serous fluid
46. cAMP - cGMP - calmodulin...
Mediate complex cell processes thru eg phosphorylation via secondary messenger (G protein) systems = signal transduction pathway - GPCR (G protein coupled receptor)
The crypts of Lieberkuhn: sm intestine pH is not right; brush border enzs won't work right
Follicular (proliferative)= 8d - Luteal (post - ovulation; corpus luteum secretions)= 13d - Menstruation (shed uterine lining if no implantation)= 5
Needs time for bile - lipase - micelle migration - enterocyte uptake
47. Both divisions (somatic - autonomic) of PNS consist of...
Needs time for bile - lipase - micelle migration - enterocyte uptake
Sensory (afferent - dorsal) - motor (efferent - ventral)
pericardial cavity - pleural cavity (contains lungs) - peritoneal cavity (abdominal)
Lipoproteins; albumin carries free fatty acids when fat is mobilized from adipose tissue - etc
48. Contrast PNS- Somatic with PNS- Autonomic
PNS- Somatic - afferent (dorsal root ganglion) + efferent (ventral horns) PNS- ANS- afferent (sensors on viscera) + SYMP - PARA pre - post - ganglionic neurons
Estrogen: steroid; stims LH in luteal surge; causes growth of female sex organs progesterone: prepares/maintains uterus for pregnancy
Where lipoprotein lipase hydrolyzes TAGs; products diffuse into target tiss (mostly liver - adipose tissue)
vitreous humor - retina - fovea
49. Sensory - motor neurons are part of which nervous system
cornea (1.4 refractory index; bends light) - pupil (size of pupil is determined by contraction state of the iris) - aqueous humor
Posterior pituitary hormone; acts on uterus - mammary glands; causes uterine contractions - milk ejection
Liposome has phospholipid bilayer
Peripheral nervous sys
50. Neuronal cell bodies have extensions ie
Serous membrane (slick - reducing friction) that forms lining of the coelom --> secretes lubricating fluid
Glycosaminoglycans - prots - AAs - lipids
Processes: axons - dendrites
= catecholamines; fight/flight; vasoconstrictors of internal organs - skin; vasodilators of skel musc; also considered stress hormones; epinephrine - norepinephrine