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MCAT Prep - 2

Subjects : mcat, science

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Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. A pinpoint iris is contracted or uncontracted
Estradiol (estrogen - steroid horm); prepares uterine wall for pregnancy; just before ovulation - release of estradiol stims LH in pos feedback
Zygote (morula) composed of eight or more cells; All cells at this stage are TOTipOTENT STEM Cells: do not grow - form by cleavage
Uncontracted: parasymp (eg opoid use)
At the collecting duct: becomes more permeable to water which passively diffuses *into the medulla* concentrating the urine

2. What is secreted into filtrate by cells of the proximal tubule?
To the organelle w/ lumen: smooth ER; they are resynthesized into TAGs
Photon (hv)- rhodopsin - conformation change - GPCR- Na less permeable - hyperpolarized rod cells - generates AP= photobleaching at visible light wavelengths (390-700nm)
Adrenal gland -- AC: steroids (cortisol - aldosterone); AM: catecholamines (epi - norepi); Islets of langerhans: peptides (insulin/glucagon) ANTAGONISTS: calcitonin (thyroid - peptide lowers Ca in blood); parathyroid hormone - peptide - vitamin D pat
Drugs - toxins - bile pigments (color the urine) - uric acid - antibiotics

3. Cell determination begins At what stage of development
After morula - with blastocyst (+8 cell count)--->totipotent to embryonic stem cell and so on
Spike in estrogen - LH levels; secondary follicle bursts - releases into body cavity - swept along by fimbriae
Faces the lumen
Eg spinal nerve - cranial nerve; Not All Nervous Tissue In Brain - SC Is CNS Tissue

4. components of interstitial fluid
Adrenocorticotropin; stims adrenal cortex release of glucocorticoids (eg cortisol - a steroid) stress hormones via second messenger system using cAMP
Glycosaminoglycans - prots - AAs - lipids
Diarrhea: excess water loss in feces; poor absorption of vitamins - minerals
Many modern drugs are ligands for GPCRs

5. serous membranes have a viscera - facing layer and a body wall - facing layer
Synthesizes lipids (including steroids); detoxifies drugs; is continuous with lumen
Visceral layer= parietal layer; serous membrane is the container of the coelom/peritoneal cavity
Four 23 N daughter cells are formed from one 46 2N mother (germ - line) cell; four haploid gametes
Eg spinal nerve - cranial nerve; Not All Nervous Tissue In Brain - SC Is CNS Tissue

6. What hormones affect the stomach?
Hormones --->stimulate exocrine glands - acetylcholine (increases all secretion of gastric pits) - gastrin (from G cells) - histamine (increases HCl secretion of parietals) ...Ach increases all secretions; gastrin increases gastric acid (parietal cel
Lower blood pH
SYMP: spinal cord --->paravetebral ganglion PARA: spinal cord - brain; cell processes --->ganglion near effector organ (preganglionic neurons) extend outside of spinal cord to synapse at ganglia - go on along postganglionic neurons
Stom= G cells (gastrin) - parietal (oxyntic); chief (peptic); mucous cells (hi ER - Golgi to make sticky glycoprots) - sm intest= enterocytes (w/brush border of maltase - sucrase - lactase - dextrinase; peptidase; lipase; nucleases); goblet cells (mu

7. exocrine types
Sudiferous (sweat) - sebaceous - digestive (bile - pancreatic enzs) - mucosal
Alpha cells; stims gluconeogenesis in liver; acts via cAMP second messenger
Water flows from the tubule - concentrating the filtrate - raising BP
Transfer signals from neuron - neuron; 90% of neurons are interneurons

8. extracellular matrix formed mainly of...
Lens will be rounded; contraction of the lens (ie focusing) is done by ciliary muscle
Ups bicarbonate secretion by pancreas; raises pH to 6.0
Peptide; stims growth of nearly all cell of body; all other anterior pituitary horms have specific targets; upregulates anabolic pathways; use of fat for energy goes up (fat - burning); increases AA transport across cell membrane (nutrient uptake)
Polysaccharides w/proteoglycans attached = glycosaminoglycans; often give pliability

9. In IBS - What is defective

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10. ligands are the messenger compounds that target secondary messenger systems on effectors
Zygotes are diploid
Testosterone upon stim by LH
Contains lysozyme - which regulates bacteria within intestine; breaks down peptidoglycans (**bact wall); innate immunity
Many modern drugs are ligands for GPCRs

11. How does the body mobilize fat stores
***starting with adipose tiss: FFAs are transported in the blood by albumin (major component of blood plasma); one albumin typically carries three fatty acid molecules but can hold up to 30 FAs
Direction of differentiation
Small amounts of hydrolyzed phospholipids and cholesterol: like other fat mols these can diffuse thru enterocyte membrane
'Microvilli function as the **primary surface of nutrient absorption in the gastrointestinal tract**. Because of this vital function - the microvillar membrane is packed with enzymes that aid in the breakdown of complex nutrients into simpler compoun

12. Where does the bolus go after mouth chews food
Moves down thru esophageal sphincter
Stomach - sm intest - spleen - pancreas from the hepatic portal vein...all blood that passes thru liver go thru flattened spaces called the ***hepatic sinusoids -->hepatic vein --->vena cava
Ectoderm: outer coverings - nervous system Mesoderm: between covering ie musc - bone - etc - endoderm: digestive tract - viscera
Adrenocorticotropin; stims adrenal cortex release of glucocorticoids (eg cortisol - a steroid) stress hormones via second messenger system using cAMP

13. week three: neurulation; mesoderm induces ectoderm; thus - NEURULATION INVOLVES SC Development - at week three
Prophase II: no crossing over b/c there are no homologous chromosomes; nuclear envelope dissolves Metaphase II: chromosomes line up at metaphase plate Anaphase II: sister chromatids separate - migrate to opp poles Telophase II: nuclear envelope reap
Contain rough ER and Golgi to make mucous; mucous is full of **glycoprots (sticky) and electrolytes*; protects epithelial tiss of stomach from low pH and lubricates stomach
Notochord (mesoderm) induces ectoderm to thicken into neural plate --->neural tube --->spinal cord
Going up - water - impermeable: salt is actively pumped out - filtrate osmolarity goes down as salt leaves

14. Sensory - motor neurons are part of which nervous system
Peripheral nervous sys
Somatic nervous sys - autonomic nervous sys
Notochord (mesoderm) induces ectoderm to thicken into neural plate --->neural tube --->spinal cord
'The hepatic portal vein is not a true vein - because it does not conduct blood directly to the heart. It is a vessel in the abdominal cavity that drains blood from the gastrointestinal tract and spleen to capillary beds in the liver.'

15. mucus cells line the stomach...
Contain rough ER and Golgi to make mucous; mucous is full of **glycoprots (sticky) and electrolytes*; protects epithelial tiss of stomach from low pH and lubricates stomach
Travels vas deferens - urethra; mixes with prostate fluids - seminal vesicles - couper's gland - etc
23 N; 23 chromosomes and haploid (no homologous chromosomes); each chromosome has two sister chromatids Male: primary spermatocyte -->REDUCTIONAL DIVISION (first stim'd at puberty by GnRH - LH-->secondary spermatocyte Female: primary oocyte (arreste
Most absorption occurs in sm intestine

16. Between meals most fats appear in blood as
Renal pyramids --->renal calyx-->renal pelvis -->ureter -->urethra
Lipoproteins; albumin carries free fatty acids when fat is mobilized from adipose tissue - etc
Photon (hv)- rhodopsin - conformation change - GPCR- Na less permeable - hyperpolarized rod cells - generates AP= photobleaching at visible light wavelengths (390-700nm)
Follicular (proliferative)= 8d - Luteal (post - ovulation; corpus luteum secretions)= 13d - Menstruation (shed uterine lining if no implantation)= 5

17. Where would materials slated for digestion go?
On the chyme exiting the stomach and entering duodenum thru the pyloric sphincter
Estradiol (estrogen - steroid horm); prepares uterine wall for pregnancy; just before ovulation - release of estradiol stims LH in pos feedback
Lysosome
Normally contracted

18. In effect LH - FSH stimulate
Lens will be rounded; contraction of the lens (ie focusing) is done by ciliary muscle
Number of centromeres - Not number of chromatids eg - two sister chromatids connected by one centromere = one chromosome
Prod of steroid hormones in testes - ovaries
The crypts of Lieberkuhn: sm intestine pH is not right; brush border enzs won't work right

19. from the loop of henle...
Ventrally (picture skeletal vertebrae)
In gastric pits; secretions combine into gastric juice
On to the distal tubule where sodium - calcium are reabsorbed - protons - bicarbonate - potassium are secreted via membrane transport proteins
Increases solute conc and osmotic pressure of the ***medulla

20. Where does the juxtaglomerular apparatus come into play...renin --->inc angiotensins -->inc aldosterone - ups BP
Fat is insoluble in blood and requires a carrier like lipoproteins (vLDL...HDL) or albumins; ...vLDL has hi triglycerides - hi cholesterol
Monitors filtrate pressure in the distal tubule; has specialized cells (granular cells) that secrete an enzyme (**renin); renin initiates regulatory cascade that produces angiotensin I - II - III that stim adrenal cortex to secrete aldosterone... ...
Peptides
Hormones --->stimulate exocrine glands - acetylcholine (increases all secretion of gastric pits) - gastrin (from G cells) - histamine (increases HCl secretion of parietals) ...Ach increases all secretions; gastrin increases gastric acid (parietal cel

21. What is gastric acid?
Direction of differentiation
HCl; secreted by parietal cells under stim by gastrin
Receive signals from receptor cell w/ ability to interact with its environment; 99% sensory input is discarded
Two perpendicular semicircular canals involved in balance - equilibrium

22. overall - fatty - prot - rich food in duod causes
Hypothalamus --->AP--->target tissues eg TSH - thyroid - T3/T4 release - increase basal metabolic rate
Secreted by delta cells of Islets of langerhans; inhibits insulin and glucagon; slows digestion
Gastric inhibitory pep; increase of pancreatic - enz activating enzymes (which cleaves zymogens like trypsinogen); increased gall bladder contraction; decreases stomach mobility
Drugs - toxins - bile pigments (color the urine) - uric acid - antibiotics

23. Important aspect of crypt of Lieberkuhn - secreted intestinal juice
Testosterone upon stim by LH
Transfer signals from neuron - neuron; 90% of neurons are interneurons
Contains lysozyme - which regulates bacteria within intestine; breaks down peptidoglycans (**bact wall); innate immunity
Only musc and esp ** liver can store large amounts

24. 3 phases of menstrual cycle
Via secondary active transport proteins (COSTS E TO FILTER BLOOD - ESTABLISH FLUID/ION BALANCE)
Liver breaks down glycogen (glycogenolysis); at hi blood sugar it builds up glycogen (glycogenesis)
At the first capillary bed of the nephron called the glomerulus which is encased by ***Bowman's capsule
Follicular phase: primary - secondary - ovulation (1 week) luteal phase: ovulation - thickening of uterine lining w/corpus luteum secretion - corpus luteum degrades (2 weeks) flow: shedding of uterine lining (4 days)

25. Energy from fat - prot - gluc
Digestion
Peptide; stims growth of nearly all cell of body; all other anterior pituitary horms have specific targets; upregulates anabolic pathways; use of fat for energy goes up (fat - burning); increases AA transport across cell membrane (nutrient uptake)
Homologous chromosomes line up w/ attachment of spindle fibers/microtubule polymers to centromeres via kinetochores; identical in appearance under light microscope to metaphase of mitosis
FAT=9 cal per gram Carbs=4.5 cal per gram - Prot=4 cal per gram - these seem to be for anhydrous forms

26. Thus - central nervous sys is...
Interneurons working to integrate signals received from the peripheral nervous system (sense organs)
Maintains hi estrogen levels; body does not recognize luteal surge - ovulation does not occur; hi progesterone can lessen shedding by thickening the uterine lining
Contain rough ER and Golgi to make mucous; mucous is full of **glycoprots (sticky) and electrolytes*; protects epithelial tiss of stomach from low pH and lubricates stomach
Low because AAs are immediately used in translation

27. physiology of gall bladder - liver and pancreatic secretions
Buildup of macromolecules in lysosome due to deficient lysosome enzymes
Facilitated diffusion from hi to lo conc
About 7.2
Combined via conjunction of pancreatic duct and common bile duct; common bile duct originates at **cystic duct where gall bladder and liver secretions combine ..cystic duct+common bile duct+pancreatic duct --->into duodenum

28. 'Cell bodies of somatic motor neurons are located in....'
Testosterone and estradiol
(haploid organism) many fungi and protozoa; individuals are typically haploid; fertilization may occur with immediate meiosis back to haploid state
Night vision
Spinal cord ventral horns; somatic motor neurons use acetylcholine for NTs (voluntary)

29. What if large intestine isn't working well
Diarrhea: excess water loss in feces; poor absorption of vitamins - minerals
Presence of fat - prot in duodenum causes release of **gastric inhibitory peptide**; result is slower stomach contraction; slower emptying into duod thru pyloric sphincter (slower chyme secretion); more time to properly digest - absorb nutrients
Nervous - muscle - epithelial (defines inner/outer) - connective (extensive matrices)
Within the paravertebral ganglion - running parallel to spinal cord

30. bundles of collecting ducts are called
Maintains hi estrogen levels; body does not recognize luteal surge - ovulation does not occur; hi progesterone can lessen shedding by thickening the uterine lining
visual (rhodopsin is receptor - derived from Vit A; conformation change occurs with photon to hyperpolarize rod cells; cone cells use photopsin for receptor) - olfactory - mood (NTs targeted by antidepressants - antipsychotics - etc; GABA is inhibit
Renal pyramids --->renal calyx-->renal pelvis -->ureter -->urethra
Duodenum (wraps around pancreas; most digestion occurs here) - jejunum (pH 7-9; 2m) - ileum

31. What determines number of chromosomes?
Raises BP; causes collecting ducts at end of nephron (kidney) to become permeable to water - which concentrates urine; coffee - beer block ADH and increase urine volume
Secrete intrinsic factor; important for absorbing vitamin B12 in sm intest
Number of centromeres - Not number of chromatids eg - two sister chromatids connected by one centromere = one chromosome
Salivary amylase (weak); sm intest amylase (breaks down large polysaccharides)

32. pancreatic enzymes are zymogens
Urine enters kidneys via artery - to arteriole - capillary bed - glomerulus - Bowman's capsule - proximal tubule - loop of henle (concentrates medulla) - distal tubule - collecting tubule - collecting duct (renal pyramids) - renal calyx - renal pelvi
Trypsinogen is activated by enterokinase in the brush border; in turn - it activates other enzymes
Normally contracted
Spike in estrogen - LH levels; secondary follicle bursts - releases into body cavity - swept along by fimbriae

33. Liver Functions
Stores blood: when expanded liver serves as blood reservoir for body - filters blood: Kupfer cells phagocytize bacteria picked up from intestines - destroys bad RBCs: also done by Kupfer cells - detoxifies blood: detoxified chemicals are excreted eit
Calcitonin (peptide; lowers blood Ca); T3/T4 (tyrosine - derived; increase basal metabolic rate); T4= thyroxine
Secondary oocyte (stim'd by LH stimulation of theca cells causing release of testosterone - converted to estradiol; eventually brings about luteal surge -->EQUATIONAL DIVISION-->ovum released during ovulation into fallopian tube; burst follicle becom
Peripheral nervous sys

34. What is feces composed of...
Size of fist; two kidneys; have cortex (steroid hormones) and medulla (catecholamines) - receives about 20% of cardiac output - blood travels down arteries - up veins -'urine is created by the kidney and emptied into the renal pelvis - which is empti
75% water/ 25% solid mass: of that solid mass: 10-20% fat = phospholipid bilayer of bacteria - slough - off enterocytes ie stomach lining (must be constantly rebuilt) 10-20% inorganic material 30% roughage = fiber = cellulose (indigestible) 2-3% prot
Determined by whether in front of or behind the lens
REABSORPTION: draws off water and ions - increases osmolarity of the medulla while slightly lowering osmolarity of the filtrate -->medulla must have hi osmolarity in order to concentrate urine at collecting duct (final step in nephron)

35. Where does blood to be filtered by kidney enter the nephron?

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36. at lo blood sugar...
Liver breaks down glycogen (glycogenolysis); at hi blood sugar it builds up glycogen (glycogenesis)
Parathyroid hormone (peptide; increases blood Ca); thus - might increase osteoclast/decrease osteoblast activity
Systems (eg digestive system consists of many organs)
Polysaccharides w/proteoglycans attached = glycosaminoglycans; often give pliability

37. trypsin is secreted by
Synthesizes lipids (including steroids); detoxifies drugs; is continuous with lumen
Pancreas; active at sm intestinal pH; hydrolyzes peptide bonds of (pepsin - digested) peptides
Follicular phase: primary - secondary - ovulation (1 week) luteal phase: ovulation - thickening of uterine lining w/corpus luteum secretion - corpus luteum degrades (2 weeks) flow: shedding of uterine lining (4 days)
Mouth - esophagus - stomach - duodenum - jejunum - ileum - ascending colon - transverse colon - descending colon - sigmoid colon - rectum - anus

38. What are phagosomes
Membrane - bound - endocytosed bodies
Corpus luteum degrades into corpus albicans
(diploid organism) humans are part of gametic life cycle ie produce gametes; diploid germ - line stem cells undergo meiosis to form haploid gametes
PH 6.0; this accomplished by pancreatic secretion of bicarbonate which ups pH

39. Where do pancreatic secretions take effect
Glucose
On the chyme exiting the stomach and entering duodenum thru the pyloric sphincter
Urine enters kidneys via artery - to arteriole - capillary bed - glomerulus - Bowman's capsule - proximal tubule - loop of henle (concentrates medulla) - distal tubule - collecting tubule - collecting duct (renal pyramids) - renal calyx - renal pelvi
Faces the lumen

40. Glycogenolysis/gluconeogenesis
Liver Functions pt. 2 - Carb metabolism: blood is sent straight to liver from sm intest thru portal vein; liver is control center for blood glucose; _______________ - fat metabolism: oxidizes fat for energy by beta - oxidation - forms most lipoprotei
Changes: volume of filtrate does not change: osmolarity of filtrate --->reabsorbed ions like sodium carry water across membrane
Contain rough ER and Golgi to make mucous; mucous is full of **glycoprots (sticky) and electrolytes*; protects epithelial tiss of stomach from low pH and lubricates stomach
**NO*** lipase digests fat; no bonds broken by bile; only opens up more SA for lipase

41. Ovum development is halted At what stage until fertilization...
Duodenum (wraps around pancreas; most digestion occurs here) - jejunum (pH 7-9; 2m) - ileum
At metaphase II of meiosis II (halted during reductional division); if fertilized - process continues toward haploid gamete
Ups bicarbonate secretion by pancreas; raises pH to 6.0
SYMP: spinal cord --->paravetebral ganglion PARA: spinal cord - brain; cell processes --->ganglion near effector organ (preganglionic neurons) extend outside of spinal cord to synapse at ganglia - go on along postganglionic neurons

42. peroxisome is derived from this
Gonadotropin releasing hormone - GnRH
ER
Injury that does not sever SC (causes deep lesion from back - front) might cause loss of feeling without full loss of motion
Stom= G cells (gastrin) - parietal (oxyntic); chief (peptic); mucous cells (hi ER - Golgi to make sticky glycoprots) - sm intest= enterocytes (w/brush border of maltase - sucrase - lactase - dextrinase; peptidase; lipase; nucleases); goblet cells (mu

43. testosterone can be aromatized to...
Estradiol
In gastric pits; secretions combine into gastric juice
Gastrulation occurs: formation of three primary germ layers = differentiation
The crypts of Lieberkuhn: sm intestine pH is not right; brush border enzs won't work right

44. Three stages of the menstrual cycle
Posterior pituitary hormone; acts on uterus - mammary glands; causes uterine contractions - milk ejection
Follicular (proliferative)= 8d - Luteal (post - ovulation; corpus luteum secretions)= 13d - Menstruation (shed uterine lining if no implantation)= 5
Digestion
Testes>Semeniferous tubules>Sertoli cells; feedback on AP FSH production

45. in mammals - gastrulation involves formation of the
Stomach - sm intest - spleen - pancreas from the hepatic portal vein...all blood that passes thru liver go thru flattened spaces called the ***hepatic sinusoids -->hepatic vein --->vena cava
Glucose and ketone bodies (not from glycogen stores)
Primitive streak - which consists of cells of the MESODERM ****
Food is digested from mouth to stomach (denaturation by gastric acid - digested by pepsin) to duodenum (more digestion); then absorption occurs in jejunum and ileum

46. lining of abdominal cavity=
Prophase II: no crossing over b/c there are no homologous chromosomes; nuclear envelope dissolves Metaphase II: chromosomes line up at metaphase plate Anaphase II: sister chromatids separate - migrate to opp poles Telophase II: nuclear envelope reap
Serous membrane (slick - reducing friction) that forms lining of the coelom --> secretes lubricating fluid
Regulated by gastrointestinal horms
Glucose = aldose fructose = ketose

47. going down the loop of Henle - water - permeable - filtrate osmolarity goes up as water leaves...
Going up - water - impermeable: salt is actively pumped out - filtrate osmolarity goes down as salt leaves
Oxidizes macromolecules; breaks down very long - chain FAs by beta - oxidation; products (acetyl - CoA) are shuttled to mitochondrion for citric acid cycle
CARB- Digesting: dextrinase (polysachs produced by hydrolysis of starch) - maltase (glucose - glucose) - sucrase (glucose - fructose) - lactase (galactose - glucose) - Protein- Digesting: peptidases - NUCLEOTIDE- Digesting: nucleosidases
Hydrostatic pressure forces some plasma thru *fenestrations of the glomerular endothelium* and into Bowman's capsule; B.C. is continuous with lumen of nephron

48. SYMP neurons originate in= PARA neurons originate in=
Receive signals from receptor cell w/ ability to interact with its environment; 99% sensory input is discarded
Direction of differentiation
Calcitonin (peptide; lowers blood Ca); T3/T4 (tyrosine - derived; increase basal metabolic rate); T4= thyroxine
SYMP: spinal cord --->paravetebral ganglion PARA: spinal cord - brain; cell processes --->ganglion near effector organ (preganglionic neurons) extend outside of spinal cord to synapse at ganglia - go on along postganglionic neurons

49. 90% digestion - absorption occurs in...
Increases surface area of food ball (bolus)
Focuses light thru the vitreous humor onto retina; acts as a converging lens (image is real - inverted)
Ganglion
Small intestine; duodenum is smallest and does most DIGESTION; jejunum is medium and does most ABSORPTION; ileum is biggest and does most absorption along with jejunum

50. these transport proteins - when concs are high enough...
'Microvilli function as the **primary surface of nutrient absorption in the gastrointestinal tract**. Because of this vital function - the microvillar membrane is packed with enzymes that aid in the breakdown of complex nutrients into simpler compoun
Can be saturated; conc of a solute is called the transport maximum --->excess goes into urine
Meiosis creates germ cells
Combined via conjunction of pancreatic duct and common bile duct; common bile duct originates at **cystic duct where gall bladder and liver secretions combine ..cystic duct+common bile duct+pancreatic duct --->into duodenum

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