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MCAT Prep - 2

Subjects : mcat, science

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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Thus - central nervous sys is...
Interneurons working to integrate signals received from the peripheral nervous system (sense organs)
Bacterial flagellin: hollow filament (not microtub); euk: 9+2 microtubule w/dynein bridges
Membrane - bound - endocytosed bodies
Secondary follicle: Theca cells differentiate from interstitial tissue - surround follicle - secrete testosterone when stimd by LH (compare to Leydig cells)

2. What is the path of a sound wave that enters the ear?
(haploid organism) many fungi and protozoa; individuals are typically haploid; fertilization may occur with immediate meiosis back to haploid state
Vitamin K - b12 - thiamin - riboflavin
Primitive streak - which consists of cells of the MESODERM ****
Outer ear= pinna (auricle)- external auditory canal - eardrum (tympanic membrane) inner ear= malleus - incus - stapes - ...oval window - cochlea - where sound is transduced into neural signal...enters cochlea at scala vestibuli - where pressure chang

3. What is a dorsal root ganglion?
Conjunction of cell body w/axon
Follicular phase: primary - secondary - ovulation (1 week) luteal phase: ovulation - thickening of uterine lining w/corpus luteum secretion - corpus luteum degrades (2 weeks) flow: shedding of uterine lining (4 days)
Collection of cell bodies; cell processes project out from both ends of ganglion; synapses with interneuron in spinal cord on one end and sensory receptor on other
Contain capillary network - lymph vessels (lacteals)

4. almost all exocytosed proteins pass through this
Gonadotropin releasing hormone - GnRH
Smooth ER
Work together to emulsify fats: bile works as a detergent to increase SA of the fat; increased SA gives more substrate to lipase for digestion
Needs time for bile - lipase - micelle migration - enterocyte uptake

5. Examples of GPCRs in sensory systems/signal transduction: What is the ligand or messenger in each case? ...SIGHT - SMELL - MOOD - FIGHT/FLIGHT etc
Trypsin(- ogen; activates other panc enzymes after it is activated by enterokinase of sm intest); chymotrypsin - amylase - lipase
visual (rhodopsin is receptor - derived from Vit A; conformation change occurs with photon to hyperpolarize rod cells; cone cells use photopsin for receptor) - olfactory - mood (NTs targeted by antidepressants - antipsychotics - etc; GABA is inhibit
Two perpendicular semicircular canals involved in balance - equilibrium
Somatic nervous sys - autonomic nervous sys

6. What is secreted into filtrate by cells of the proximal tubule?
Number of centromeres - Not number of chromatids eg - two sister chromatids connected by one centromere = one chromosome
At metaphase II of meiosis II (halted during reductional division); if fertilized - process continues toward haploid gamete
Can be saturated; conc of a solute is called the transport maximum --->excess goes into urine
Drugs - toxins - bile pigments (color the urine) - uric acid - antibiotics

7. What is the pH at the entrance to the duodenum
Can be saturated; conc of a solute is called the transport maximum --->excess goes into urine
Micelles; micelles transport lipase products to enterocytes for absorption at brush border
Called a tract in the CNS; bundling together of axons/dendrites thru which many diff signals pass; many many neurons are bundled together into a single nerve
PH 6.0; this accomplished by pancreatic secretion of bicarbonate which ups pH

8. Glycogenolysis/gluconeogenesis
Which is why lactase - maltase - dextrinase - sucrase are on brush border
Liver Functions pt. 2 - Carb metabolism: blood is sent straight to liver from sm intest thru portal vein; liver is control center for blood glucose; _______________ - fat metabolism: oxidizes fat for energy by beta - oxidation - forms most lipoprotei
Notochord (mesoderm) induces ectoderm to thicken into neural plate --->neural tube --->spinal cord
Peptide; responsible for luteal surge (driven in part by LH-->testosterone -->estradiol -->LH positive feedback); results in ovulation (follicle bursting) - releasing egg into fallopian tube/oviduct

9. Liver Functions
Low because AAs are immediately used in translation
Stores blood: when expanded liver serves as blood reservoir for body - filters blood: Kupfer cells phagocytize bacteria picked up from intestines - destroys bad RBCs: also done by Kupfer cells - detoxifies blood: detoxified chemicals are excreted eit
Glucose = aldose fructose = ketose
'visceral organs develop adjacent to a cavity and invaginate into the bag - like coelom'

10. 90% digestion - absorption occurs in...
Tight regulation of parietal cells needed b/c gastric acid secretion is E- intensive; parietal cells are hi in mitochons
'visceral organs develop adjacent to a cavity and invaginate into the bag - like coelom'
Meiosis creates germ cells
Small intestine; duodenum is smallest and does most DIGESTION; jejunum is medium and does most ABSORPTION; ileum is biggest and does most absorption along with jejunum

11. PNS is broken down into
Only musc and esp ** liver can store large amounts
Lots of energy; eg neurons have hi glucose need for 3Na out 2K in ATPase; stomach epithel tiss needs E for parietal cells to pump protons into lumen and bicarbonate into blood
Injury that does not sever SC (causes deep lesion from back - front) might cause loss of feeling without full loss of motion
Somatic nervous sys - autonomic nervous sys

12. What is a toxic byproduct of gluconeogenesis from proteins
Dehydration reaction; broken apart with enzyme - catalyzed hydrolysis
Ammonia; must be converted to urea by liver and excreted in urine by kidney
Result is proton secreted into lumen - bicarbonate into interstitial fluid (diffuses into blood); result is also increased blood pH and decreased pH stomach
Prophase II: no crossing over b/c there are no homologous chromosomes; nuclear envelope dissolves Metaphase II: chromosomes line up at metaphase plate Anaphase II: sister chromatids separate - migrate to opp poles Telophase II: nuclear envelope reap

13. what happens when glycogen stores are saturated and blood sugar remains high?
Posterior pituitary hormone; acts on uterus - mammary glands; causes uterine contractions - milk ejection
Fat synthesis; carbs stored as free fatty acids - esterified to TAGs (requires small amount of E)
'Microvilli function as the **primary surface of nutrient absorption in the gastrointestinal tract**. Because of this vital function - the microvillar membrane is packed with enzymes that aid in the breakdown of complex nutrients into simpler compoun
Combined via conjunction of pancreatic duct and common bile duct; common bile duct originates at **cystic duct where gall bladder and liver secretions combine ..cystic duct+common bile duct+pancreatic duct --->into duodenum

14. When 'coumadin targets liver enzymes to act as anticoagulant'...
It targets liver conc of prothrombin - fibrinogen etc
Combined via conjunction of pancreatic duct and common bile duct; common bile duct originates at **cystic duct where gall bladder and liver secretions combine ..cystic duct+common bile duct+pancreatic duct --->into duodenum
Comes into play in the large intestine - where vitamin b12 is absorbed w/help of E. coli; thus; must travel thru bloodstream to large intestine
Prod of steroid hormones in testes - ovaries

15. So - following blastocyst implantation (4d) - at approx 2 weeks past fertilization
75% water/ 25% solid mass: of that solid mass: 10-20% fat = phospholipid bilayer of bacteria - slough - off enterocytes ie stomach lining (must be constantly rebuilt) 10-20% inorganic material 30% roughage = fiber = cellulose (indigestible) 2-3% prot
At the collecting duct: becomes more permeable to water which passively diffuses *into the medulla* concentrating the urine
Gastrulation occurs: formation of three primary germ layers = differentiation
'visceral organs develop adjacent to a cavity and invaginate into the bag - like coelom'

16. In effect LH - FSH stimulate
Secondary oocyte (stim'd by LH stimulation of theca cells causing release of testosterone - converted to estradiol; eventually brings about luteal surge -->EQUATIONAL DIVISION-->ovum released during ovulation into fallopian tube; burst follicle becom
Prod of steroid hormones in testes - ovaries
Glycosaminoglycans - prots - AAs - lipids
Homologous chromosomes separate - migrate towards opposite poles/centrioles

17. What is the net effect of the loop of Henle
Determined by whether in front of or behind the lens
REABSORPTION: draws off water and ions - increases osmolarity of the medulla while slightly lowering osmolarity of the filtrate -->medulla must have hi osmolarity in order to concentrate urine at collecting duct (final step in nephron)
Estradiol
Calcitonin (peptide; lowers blood Ca); T3/T4 (tyrosine - derived; increase basal metabolic rate); T4= thyroxine

18. inhibin secreted by
Smooth ER
Inner lining of circulatory system
Testes>Semeniferous tubules>Sertoli cells; feedback on AP FSH production
Size of fist; two kidneys; have cortex (steroid hormones) and medulla (catecholamines) - receives about 20% of cardiac output - blood travels down arteries - up veins -'urine is created by the kidney and emptied into the renal pelvis - which is empti

19. Sensory neuron cell bodies vs. somatic motor cell bodies
Zygote (fertilization in fallopian tubes); morula (up to 8 cells - undifferentiated ie totipotent); blastocyst (4+ days - implants into uterus; HCG secretion stims corpus luteum; gradually placenta replaces HCG as estrogen/progest source; cells not t
Somatic sensory = dorsal root ganglia (outside spinal cord); somatic effector = ventral horns of spinal cord
Drugs - toxins - bile pigments (color the urine) - uric acid - antibiotics
Corpus luteum degrades into corpus albicans

20. After meiosis II...
Four 23 N daughter cells are formed from one 46 2N mother (germ - line) cell; four haploid gametes
Ketone bodies; thus excessive reliance on fat for energy (eg low carb diets) results in ketosis; blood acidity increases
Sorts - modifies - concentrates proteins from the ER
Receive signals from receptor cell w/ ability to interact with its environment; 99% sensory input is discarded

21. FLAT PG: LH
Peptide; responsible for luteal surge (driven in part by LH-->testosterone -->estradiol -->LH positive feedback); results in ovulation (follicle bursting) - releasing egg into fallopian tube/oviduct
Testes>Semeniferous tubules>Sertoli cells; feedback on AP FSH production
**only para effectors have muscarinic receptors; symp effectors are adrenergic (epi - norepi); **neuromuscular junction uses nicotinic receptors
From lumenal (apical) to enterocyte to basolateral side of epithelial tissue

22. micelles also pick up
Posterior pituitary hormone; acts on uterus - mammary glands; causes uterine contractions - milk ejection
Facilitated diffusion from hi to lo conc
Trypsinogen is activated by enterokinase in the brush border; in turn - it activates other enzymes
Small amounts of hydrolyzed phospholipids and cholesterol: like other fat mols these can diffuse thru enterocyte membrane

23. alpha - amylase in the mouth digests what kind of bond
Food is digested from mouth to stomach (denaturation by gastric acid - digested by pepsin) to duodenum (more digestion); then absorption occurs in jejunum and ileum
Alpha 1-4 and 1-6 (branching) glycosidic linkages
Somatic sensory = dorsal root ganglia (outside spinal cord); somatic effector = ventral horns of spinal cord
The wall of the body or of a body cavity or hollow structure

24. A pinpoint iris is contracted or uncontracted
Pancreatic duct (made of acinar cells?)
Uncontracted: parasymp (eg opoid use)
Pancreas; active at sm intestinal pH; hydrolyzes peptide bonds of (pepsin - digested) peptides
Primitive streak - which consists of cells of the MESODERM ****

25. At post - two weeks ovulation
Dehydration reaction; broken apart with enzyme - catalyzed hydrolysis
Interneurons working to integrate signals received from the peripheral nervous system (sense organs)
Corpus luteum degrades into corpus albicans
The wall of the body or of a body cavity or hollow structure

26. How is the follicle developed during oogenesis
Glucose
Posterior pituitary hormone; acts on uterus - mammary glands; causes uterine contractions - milk ejection
Stomach - sm intest - spleen - pancreas from the hepatic portal vein...all blood that passes thru liver go thru flattened spaces called the ***hepatic sinusoids -->hepatic vein --->vena cava
Arrested at primary oocyte; hypothalamus GnRH->FSH released at puberty stims granulosa cell development; granulosa secrete zona pellucida = primary follicle

27. fructose enters enterocyte by
Oxytocin and ADH (aka vasopressin)
Facilitated diffusion: no symport w/ secondary transport
In liver (RBC recycling of heme); stored in gall bladder; released via cystic duct to common bile duct (shared w/liver); common bile duct joins up with panc duct...everything feeds into the sm intest at the ampulla of vater**
- filtration occurs at the fenestrations of the renal corpuscle - most reabsorption and secretion occur in the proximal tubule - medulla is concentrated in the loop of henle - sodium and calcium are reabsorbed in the distal tubule -->collecting tubul

28. What do lipases do
Below hypothalamus
Posterior pituitary hormone; acts on uterus - mammary glands; causes uterine contractions - milk ejection
Prophase I: crossing over occurs; nuclear envelope is absorbed into ER; chromosomes condense)
Break down TAGs to monoglycerides and free fatty acids

29. trypsin is secreted by
Thru tight junctions by favorable osmotic gradient
REABSORPTION: draws off water and ions - increases osmolarity of the medulla while slightly lowering osmolarity of the filtrate -->medulla must have hi osmolarity in order to concentrate urine at collecting duct (final step in nephron)
Pancreas; active at sm intestinal pH; hydrolyzes peptide bonds of (pepsin - digested) peptides
- parietal cells (**oxyntic= hi oxygen consumption - hi E??): have hi conc mito; need lots of energy to create proton gradient; thus - responsible for extremely harsh pH conditions in stom; denaturing conditions - chief cells (peptic): synthesize pep

30. portal vein physiology...

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31. Gastrin from G cells stims parietal cells...
Tight regulation of parietal cells needed b/c gastric acid secretion is E- intensive; parietal cells are hi in mitochons
An ether phospholipid; hi conc in myelin; thus - hi conc in heart tiss - nervous tiss
Spike in estrogen - LH levels; secondary follicle bursts - releases into body cavity - swept along by fimbriae
Follicular (proliferative)= 8d - Luteal (post - ovulation; corpus luteum secretions)= 13d - Menstruation (shed uterine lining if no implantation)= 5

32. axon hillock physiology
Conjunction of cell body w/axon
Smooth ER
Pancreatic duct (made of acinar cells?)
Facilitated diffusion: no symport w/ secondary transport

33. Contrast PNS- Somatic with PNS- Autonomic
Stims release of tyrosine - derived horms T3/T4 (increase basal metabolic rate); TSH increases thyroid cell size - number - rate of T3/T4 synth -----> thus - iodine deficiency causes swollen thyroid due to lack of neg feedback onto TSH in anterior pi
Membrane - bound - endocytosed bodies
PNS- Somatic - afferent (dorsal root ganglion) + efferent (ventral horns) PNS- ANS- afferent (sensors on viscera) + SYMP - PARA pre - post - ganglionic neurons
Adrenal gland -- AC: steroids (cortisol - aldosterone); AM: catecholamines (epi - norepi); Islets of langerhans: peptides (insulin/glucagon) ANTAGONISTS: calcitonin (thyroid - peptide lowers Ca in blood); parathyroid hormone - peptide - vitamin D pat

34. How do nutrients move?
Peptide; responsible for luteal surge (driven in part by LH-->testosterone -->estradiol -->LH positive feedback); results in ovulation (follicle bursting) - releasing egg into fallopian tube/oviduct
From lumenal (apical) to enterocyte to basolateral side of epithelial tissue
At the collecting duct: becomes more permeable to water which passively diffuses *into the medulla* concentrating the urine
Fat is insoluble in blood and requires a carrier like lipoproteins (vLDL...HDL) or albumins; ...vLDL has hi triglycerides - hi cholesterol

35. Path of food entering body...
Glucose
Nitrogen
Mouth - esophagus - stomach - duodenum - jejunum - ileum - ascending colon - transverse colon - descending colon - sigmoid colon - rectum - anus
Uncontracted: parasymp (eg opoid use)

36. Beta - oxidation in liver produces...
(diploid organism) humans are part of gametic life cycle ie produce gametes; diploid germ - line stem cells undergo meiosis to form haploid gametes
Ketone bodies; thus excessive reliance on fat for energy (eg low carb diets) results in ketosis; blood acidity increases
75% water/ 25% solid mass: of that solid mass: 10-20% fat = phospholipid bilayer of bacteria - slough - off enterocytes ie stomach lining (must be constantly rebuilt) 10-20% inorganic material 30% roughage = fiber = cellulose (indigestible) 2-3% prot
Gall bladder - pancreatic secretions increase - arrive via ampulla of vater (duct glands); insulin secretion increases (fed state; ductless glands)

37. fat digestion is time - intensive
= catecholamines; fight/flight; vasoconstrictors of internal organs - skin; vasodilators of skel musc; also considered stress hormones; epinephrine - norepinephrine
(diploid and haploid individuals = ALTERNATION of GENERATIONS) a fusion of gametic and zygotic life cycles
Creates one ovum (23 N) and three polar bodies
Needs time for bile - lipase - micelle migration - enterocyte uptake

38. E storage per unit mass
Follicular (proliferative)= 8d - Luteal (post - ovulation; corpus luteum secretions)= 13d - Menstruation (shed uterine lining if no implantation)= 5
Estradiol
Carbohydrates are highly hydrated: one water mol per carbon mol - fats are anhydrous: contain more reduced carbons per unit mass - altogether fats contain 6X energy per unit mass
Pancreatic duct (made of acinar cells?)

39. small intestine=
Somatic nervous sys - autonomic nervous sys
Duodenum (wraps around pancreas; most digestion occurs here) - jejunum (pH 7-9; 2m) - ileum
(diploid and haploid individuals = ALTERNATION of GENERATIONS) a fusion of gametic and zygotic life cycles
Peptide; prolactin promotes milk production; prolactin release is stimulated by act of suckling - which in turn inhibits menstrual cycle

40. What does peptic refer to in general
Injury that does not sever SC (causes deep lesion from back - front) might cause loss of feeling without full loss of motion
Stores blood: when expanded liver serves as blood reservoir for body - filters blood: Kupfer cells phagocytize bacteria picked up from intestines - destroys bad RBCs: also done by Kupfer cells - detoxifies blood: detoxified chemicals are excreted eit
Increases solute conc and osmotic pressure of the ***medulla
Digestion

41. what else is located in the inner ear (not directly related to auditory)
Within the paravertebral ganglion - running parallel to spinal cord
Steroid; target tissue is distal convoluted tubule of nephron and collecting duct; increases blood mineral concentration; potassium - protons secreted (blood pH increases); sodium - chloride reabsorbed (BP increases)
Two perpendicular semicircular canals involved in balance - equilibrium
Direction of differentiation

42. What are the memb - bound enzymes of the brush border?
CARB- Digesting: dextrinase (polysachs produced by hydrolysis of starch) - maltase (glucose - glucose) - sucrase (glucose - fructose) - lactase (galactose - glucose) - Protein- Digesting: peptidases - NUCLEOTIDE- Digesting: nucleosidases
Inner lining of circulatory system
Eukaryotes
AAs enter bloodstream for uptake by all cells (esp liver). If intracellular prot conc is at max AAs can be converted to fats or glucose via gluconeogenesis. Byproduct of gluconeo is ammonia --->urea.

43. PNS nerve signal
Peristalsis (esophagus) and segmentation (bi - directional=mixing)
Signal picked up by sensory cell - goes thru dorsal root ganglion to SC - may continue to interneurons in brain or simple reflex arc in SC - brain integrates info and decides (voluntary) response - travels back down SC to appropriate ventral root gan
Salivary amylase (weak); sm intest amylase (breaks down large polysaccharides)
Only musc and esp ** liver can store large amounts

44. Kidney
ER
Paracrine (local) - endocrine (longer distance)
Excretes waste products: urea - uric acid - ammonia - phosphate - maintains homeostasis: including body fluid volume (water reabsorption) and solute composition (mineral balance - nutrient reabsorption) - controls *plasma* pH: antiport of Na/K and pr
Albumin increases osmolarity of blood; increases osmotic pressure

45. What is a nerve? (PNS)
ER
Posterior pituitary hormone; acts on uterus - mammary glands; causes uterine contractions - milk ejection
Called a tract in the CNS; bundling together of axons/dendrites thru which many diff signals pass; many many neurons are bundled together into a single nerve
Primitive streak - which consists of cells of the MESODERM ****

46. serous membranes have a viscera - facing layer and a body wall - facing layer
Visceral layer= parietal layer; serous membrane is the container of the coelom/peritoneal cavity
Homologous chromosomes line up w/ attachment of spindle fibers/microtubule polymers to centromeres via kinetochores; identical in appearance under light microscope to metaphase of mitosis
Zygotes are diploid
Fovea (highest amount of cones)

47. Four tissues
Maintains hi estrogen levels; body does not recognize luteal surge - ovulation does not occur; hi progesterone can lessen shedding by thickening the uterine lining
Nervous - muscle - epithelial (defines inner/outer) - connective (extensive matrices)
**NO*** lipase digests fat; no bonds broken by bile; only opens up more SA for lipase
Bacterial flagellin: hollow filament (not microtub); euk: 9+2 microtubule w/dynein bridges

48. zygotic life cycle
Increase surface area of sm intestine; this improves digestion (enzymes adsorbed to villi) and absorption
(haploid organism) many fungi and protozoa; individuals are typically haploid; fertilization may occur with immediate meiosis back to haploid state
RBCs - large proteins; What does enter is called the filtrate
Stores blood: when expanded liver serves as blood reservoir for body - filters blood: Kupfer cells phagocytize bacteria picked up from intestines - destroys bad RBCs: also done by Kupfer cells - detoxifies blood: detoxified chemicals are excreted eit

49. How is glucose absorbed in sm intest
via symport - secondary transport (ie by pre - established - ATP- intensive) with Na gradient into enterocyte......with no Na gradient (ie without ATP) carbohydrate monomers could not be transported in
sucrose (gluc+fruc) - lactose (gluc+galactose) - starch (gluc+gluc)
Presence of fat - prot in duodenum causes release of **gastric inhibitory peptide**; result is slower stomach contraction; slower emptying into duod thru pyloric sphincter (slower chyme secretion); more time to properly digest - absorb nutrients
Lipoproteins; albumin carries free fatty acids when fat is mobilized from adipose tissue - etc

50. Anterior eye vs. posterior eye
Maintains hi estrogen levels; body does not recognize luteal surge - ovulation does not occur; hi progesterone can lessen shedding by thickening the uterine lining
Stom= G cells (gastrin) - parietal (oxyntic); chief (peptic); mucous cells (hi ER - Golgi to make sticky glycoprots) - sm intest= enterocytes (w/brush border of maltase - sucrase - lactase - dextrinase; peptidase; lipase; nucleases); goblet cells (mu
Normally contracted
Determined by whether in front of or behind the lens

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