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MCAT Prep - 2

Subjects : mcat, science

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Answer 50 questions in 15 minutes.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. For focal point that is nearby - what will the lens look like
Lens will be rounded; contraction of the lens (ie focusing) is done by ciliary muscle
Determined by whether in front of or behind the lens
Travels vas deferens - urethra; mixes with prostate fluids - seminal vesicles - couper's gland - etc
PNS- Somatic - afferent (dorsal root ganglion) + efferent (ventral horns) PNS- ANS- afferent (sensors on viscera) + SYMP - PARA pre - post - ganglionic neurons

2. Path of urine

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3. Adrenal medulla hormones (TYR- DERIVED)
Oxidizes macromolecules; breaks down very long - chain FAs by beta - oxidation; products (acetyl - CoA) are shuttled to mitochondrion for citric acid cycle
cornea (1.4 refractory index; bends light) - pupil (size of pupil is determined by contraction state of the iris) - aqueous humor
= catecholamines; fight/flight; vasoconstrictors of internal organs - skin; vasodilators of skel musc; also considered stress hormones; epinephrine - norepinephrine
Lots of water - minerals (electrolyte balance) - vitamins (aided by gut bacteria)

4. What is gastric acid?
The crypts of Lieberkuhn: sm intestine pH is not right; brush border enzs won't work right
Secreted by implanted egg; HCG prevents degeneration of the corpus luteum; HCG in blood/urine is first sign of pregnancy
Inactive: rhodopsin is activated by photons; activated rhodopsin hyperpolarizes rod cells - causes photobleaching
HCl; secreted by parietal cells under stim by gastrin

5. Meiosis I: REDUCTIONAL DIVISION Interphase: G1 (growth; enzymes - structural proteins needed for gametic production are synthesized); S (DNA of homologous chromosomes is duplicated; mother cell goes from 46 2N to 46 2N with sister chromosomes connect
Fat synthesis; carbs stored as free fatty acids - esterified to TAGs (requires small amount of E)
Oxidizes macromolecules; breaks down very long - chain FAs by beta - oxidation; products (acetyl - CoA) are shuttled to mitochondrion for citric acid cycle
Prophase I: crossing over occurs; nuclear envelope is absorbed into ER; chromosomes condense)
Chyme (by combined activity of exocrine glands)

6. In other words...
Zygotes are diploid
ER
Food is digested from mouth to stomach (denaturation by gastric acid - digested by pepsin) to duodenum (more digestion); then absorption occurs in jejunum and ileum
Carry signals to musc OR Gland

7. inhibin secreted by
Testes>Semeniferous tubules>Sertoli cells; feedback on AP FSH production
From lumenal (apical) to enterocyte to basolateral side of epithelial tissue
Maintains hi estrogen levels; body does not recognize luteal surge - ovulation does not occur; hi progesterone can lessen shedding by thickening the uterine lining
Normally contracted

8. What is the path of a sound wave that enters the ear?
pericardial cavity - pleural cavity (contains lungs) - peritoneal cavity (abdominal)
(haploid organism) many fungi and protozoa; individuals are typically haploid; fertilization may occur with immediate meiosis back to haploid state
Adrenocorticotropin; stims adrenal cortex release of glucocorticoids (eg cortisol - a steroid) stress hormones via second messenger system using cAMP
Outer ear= pinna (auricle)- external auditory canal - eardrum (tympanic membrane) inner ear= malleus - incus - stapes - ...oval window - cochlea - where sound is transduced into neural signal...enters cochlea at scala vestibuli - where pressure chang

9. insulin secreted by
Beta cells
Somatic nervous sys - autonomic nervous sys
Trypsin(- ogen; activates other panc enzymes after it is activated by enterokinase of sm intest); chymotrypsin - amylase - lipase
Lumen (ie continuous w/body cavity) and cytosol

10. 'Cell bodies of somatic motor neurons are located in....'
Increases solute conc and osmotic pressure of the ***medulla
cornea (1.4 refractory index; bends light) - pupil (size of pupil is determined by contraction state of the iris) - aqueous humor
Spinal cord ventral horns; somatic motor neurons use acetylcholine for NTs (voluntary)
sucrose (gluc+fruc) - lactose (gluc+galactose) - starch (gluc+gluc)

11. Path of food entering body...
Gonadotropin releasing hormone - GnRH
Sensory (afferent - dorsal) - motor (efferent - ventral)
Outermost layer of blood vessel
Mouth - esophagus - stomach - duodenum - jejunum - ileum - ascending colon - transverse colon - descending colon - sigmoid colon - rectum - anus

12. Meiosis I Telophase I
Nuclear envelope reassembled in daughter cells; cytokinesis occurs; nucleoli reappear (site of rRNA synthesis)
visual (rhodopsin is receptor - derived from Vit A; conformation change occurs with photon to hyperpolarize rod cells; cone cells use photopsin for receptor) - olfactory - mood (NTs targeted by antidepressants - antipsychotics - etc; GABA is inhibit
All carbs absorbed at enterocytes are carried to liver by portal vein
Arrested at primary oocyte; hypothalamus GnRH->FSH released at puberty stims granulosa cell development; granulosa secrete zona pellucida = primary follicle

13. Neuronal cell bodies have extensions ie
Processes: axons - dendrites
ER
Lipoproteins; albumin carries free fatty acids when fat is mobilized from adipose tissue - etc
Size of fist; two kidneys; have cortex (steroid hormones) and medulla (catecholamines) - receives about 20% of cardiac output - blood travels down arteries - up veins -'urine is created by the kidney and emptied into the renal pelvis - which is empti

14. protein absorption at enterocyte
Stims release of tyrosine - derived horms T3/T4 (increase basal metabolic rate); TSH increases thyroid cell size - number - rate of T3/T4 synth -----> thus - iodine deficiency causes swollen thyroid due to lack of neg feedback onto TSH in anterior pi
Amino acid monomers - di - tri absorbed by symport at enterocyte; each AA has slightly diff mechanism; from entero - AAs enter bloodstream where they are taken up by all cells of the body - esp the liver by active or facilitated transport (NEVER PASS
Form barrier to extracellular fluid
Only musc and esp ** liver can store large amounts

15. sensory (afferent)/interneurons/motor (efferent)
Neurons may perform one of three functions....
Zygote (fertilization in fallopian tubes); morula (up to 8 cells - undifferentiated ie totipotent); blastocyst (4+ days - implants into uterus; HCG secretion stims corpus luteum; gradually placenta replaces HCG as estrogen/progest source; cells not t
Contains lysozyme - which regulates bacteria within intestine; breaks down peptidoglycans (**bact wall); innate immunity
Most absorption occurs in sm intestine

16. Sensory neuron cell bodies vs. somatic motor cell bodies
Somatic sensory = dorsal root ganglia (outside spinal cord); somatic effector = ventral horns of spinal cord
- filtration occurs at the fenestrations of the renal corpuscle - most reabsorption and secretion occur in the proximal tubule - medulla is concentrated in the loop of henle - sodium and calcium are reabsorbed in the distal tubule -->collecting tubul
Glucose and ketone bodies (not from glycogen stores)
Pepsin - secreted by chief cells in the stomach epithelial lining and active at low pH - breaks down proteins to polypeptides. Protein hydrolysis is aided by the highly acidic environment (hi gastric acid from parietal cells). Polypeptides are squirt

17. sporic life cycle
(diploid and haploid individuals = ALTERNATION of GENERATIONS) a fusion of gametic and zygotic life cycles
Parathyroid hormone (peptide; increases blood Ca); thus - might increase osteoclast/decrease osteoblast activity
90-140 mg/dl
Water flows from the tubule - concentrating the filtrate - raising BP

18. Where does blood to be filtered by kidney enter the nephron?

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19. Where do absorbed fats go in the enterocyte
To the organelle w/ lumen: smooth ER; they are resynthesized into TAGs
Injury that does not sever SC (causes deep lesion from back - front) might cause loss of feeling without full loss of motion
Peptides
Epithelial tissue near semniferous tubules

20. Gland: ovaries
- enterocytes w/ *microvilli brush border*: membrane - bound digestive enzymes for carbs - fats - nucleic acids - goblet cells: secrete mucous - Deep between villi are the intestinal exocrine glands - the crypts of Lieberkuhn - which secrete pH 7.6 i
Many modern drugs are ligands for GPCRs
Liver breaks down glycogen (glycogenolysis); at hi blood sugar it builds up glycogen (glycogenesis)
Estrogen: steroid; stims LH in luteal surge; causes growth of female sex organs progesterone: prepares/maintains uterus for pregnancy

21. What if large intestine isn't working well
Alpha 1-4 and 1-6 (branching) glycosidic linkages
Prophase II: no crossing over b/c there are no homologous chromosomes; nuclear envelope dissolves Metaphase II: chromosomes line up at metaphase plate Anaphase II: sister chromatids separate - migrate to opp poles Telophase II: nuclear envelope reap
Amino acid monomers - di - tri absorbed by symport at enterocyte; each AA has slightly diff mechanism; from entero - AAs enter bloodstream where they are taken up by all cells of the body - esp the liver by active or facilitated transport (NEVER PASS
Diarrhea: excess water loss in feces; poor absorption of vitamins - minerals

22. At post - two weeks ovulation
PNS- Somatic - afferent (dorsal root ganglion) + efferent (ventral horns) PNS- ANS- afferent (sensors on viscera) + SYMP - PARA pre - post - ganglionic neurons
- parietal cells (**oxyntic= hi oxygen consumption - hi E??): have hi conc mito; need lots of energy to create proton gradient; thus - responsible for extremely harsh pH conditions in stom; denaturing conditions - chief cells (peptic): synthesize pep
Corpus luteum degrades into corpus albicans
It is the animal counterpart of starch; it is more highly- branched - thus releases more glucose monomers upon repeated hydrolysis than starch

23. when cells hit their limit for prot storage...
Synthesizes lipids (including steroids); detoxifies drugs; is continuous with lumen
AAs can be burned for energy or converted to fat for storage
Increases surface area of food ball (bolus)
Trypsin(- ogen; activates other panc enzymes after it is activated by enterokinase of sm intest); chymotrypsin - amylase - lipase

24. small intestine=
Ketone bodies; thus excessive reliance on fat for energy (eg low carb diets) results in ketosis; blood acidity increases
Gastrulation occurs: formation of three primary germ layers = differentiation
Duodenum (wraps around pancreas; most digestion occurs here) - jejunum (pH 7-9; 2m) - ileum
Glucose

25. Spinal cord horns (thick knobs) point
Hypothalamus --->AP--->target tissues eg TSH - thyroid - T3/T4 release - increase basal metabolic rate
Ventrally (picture skeletal vertebrae)
Nourishes follicle growth; stimulates granulosa cell growth around primary oocyte at puberty = primary follicle; also - stimulates Sertoli cells in males
- parietal cells (**oxyntic= hi oxygen consumption - hi E??): have hi conc mito; need lots of energy to create proton gradient; thus - responsible for extremely harsh pH conditions in stom; denaturing conditions - chief cells (peptic): synthesize pep

26. Where else does ADH act
Secrete intrinsic factor; important for absorbing vitamin B12 in sm intest
Buildup of macromolecules in lysosome due to deficient lysosome enzymes
Outermost layer of blood vessel
At the collecting duct: becomes more permeable to water which passively diffuses *into the medulla* concentrating the urine

27. Different tissues working together
Homologous chromosomes separate - migrate towards opposite poles/centrioles
Organs
Carbohydrates are highly hydrated: one water mol per carbon mol - fats are anhydrous: contain more reduced carbons per unit mass - altogether fats contain 6X energy per unit mass
Result: stress reaction; increase glycogenolysis - gluconeogenesis; fat/prot breakdown; increase blood glucose

28. Some PNS nerves are found in brain - spinal cord
Nitrogen
Parathyroid hormone (peptide; increases blood Ca); thus - might increase osteoclast/decrease osteoblast activity
Estradiol (estrogen - steroid horm); prepares uterine wall for pregnancy; just before ovulation - release of estradiol stims LH in pos feedback
Eg spinal nerve - cranial nerve; Not All Nervous Tissue In Brain - SC Is CNS Tissue

29. Contrast PNS- Somatic with PNS- Autonomic
PNS- Somatic - afferent (dorsal root ganglion) + efferent (ventral horns) PNS- ANS- afferent (sensors on viscera) + SYMP - PARA pre - post - ganglionic neurons
Pepsin - secreted by chief cells in the stomach epithelial lining and active at low pH - breaks down proteins to polypeptides. Protein hydrolysis is aided by the highly acidic environment (hi gastric acid from parietal cells). Polypeptides are squirt
Water flows from the tubule - concentrating the filtrate - raising BP
pericardial cavity - pleural cavity (contains lungs) - peritoneal cavity (abdominal)

30. pancreatic enzymes are zymogens
Trypsinogen is activated by enterokinase in the brush border; in turn - it activates other enzymes
Moves thru lymph sys; emptied into large veins (thus into bloodstream) of the neck at Thoracic duct
vitreous humor - retina - fovea
Lysosome

31. How long are peptides when absorbed at brush border
Oxidizes macromolecules; breaks down very long - chain FAs by beta - oxidation; products (acetyl - CoA) are shuttled to mitochondrion for citric acid cycle
Processes: axons - dendrites
Di - tri - peptides; inside enterocytes are hydrolyzed to amino acids
Amino acid monomers - di - tri absorbed by symport at enterocyte; each AA has slightly diff mechanism; from entero - AAs enter bloodstream where they are taken up by all cells of the body - esp the liver by active or facilitated transport (NEVER PASS

32. albumin has What affect on blood osmotic pressure
Adrenal gland -- AC: steroids (cortisol - aldosterone); AM: catecholamines (epi - norepi); Islets of langerhans: peptides (insulin/glucagon) ANTAGONISTS: calcitonin (thyroid - peptide lowers Ca in blood); parathyroid hormone - peptide - vitamin D pat
Lowers osmolarity of the filtrate (IONS - Water Are Taken Back Up By The Kidney)--->at the end of the distal tubule (the collecting tubule) is where aldosterone acts - along with the JGA
Normally contracted
Albumin increases osmolarity of blood; increases osmotic pressure

33. FSH - LH - HCG - inhibin are...
Peptides
All carbs absorbed at enterocytes are carried to liver by portal vein
90-140 mg/dl
Trypsinogen is activated by enterokinase in the brush border; in turn - it activates other enzymes

34. chylomicron concentration in blood after meal
Peak at 1-2hr after meal; chylomicrons themselves have half - life of about 1hr after formation in enterocytes
Where lipoprotein lipase hydrolyzes TAGs; products diffuse into target tiss (mostly liver - adipose tissue)
Lumen (ie continuous w/body cavity) and cytosol
Changes: volume of filtrate does not change: osmolarity of filtrate --->reabsorbed ions like sodium carry water across membrane

35. On what surface of the retina is the eye most sensitive
Two perpendicular semicircular canals involved in balance - equilibrium
Mouth - esophagus - stomach - duodenum - jejunum - ileum - ascending colon - transverse colon - descending colon - sigmoid colon - rectum - anus
Fovea (highest amount of cones)
Stims release of tyrosine - derived horms T3/T4 (increase basal metabolic rate); TSH increases thyroid cell size - number - rate of T3/T4 synth -----> thus - iodine deficiency causes swollen thyroid due to lack of neg feedback onto TSH in anterior pi

36. Chewing does what?
Albumin increases osmolarity of blood; increases osmotic pressure
Increases surface area of food ball (bolus)
Gastric inhibitory pep; increase of pancreatic - enz activating enzymes (which cleaves zymogens like trypsinogen); increased gall bladder contraction; decreases stomach mobility
Has memb - bound organelles - etc...

37. Posterior eye
vitreous humor - retina - fovea
90-140 mg/dl
Micelles; micelles (made of bile) go back and forth between brush border and chyme
Many modern drugs are ligands for GPCRs

38. What surrounds the hydrophilic heads of the new TAGs
Micelles; micelles transport lipase products to enterocytes for absorption at brush border
Homologous chromosomes line up w/ attachment of spindle fibers/microtubule polymers to centromeres via kinetochores; identical in appearance under light microscope to metaphase of mitosis
REABSORPTION: draws off water and ions - increases osmolarity of the medulla while slightly lowering osmolarity of the filtrate -->medulla must have hi osmolarity in order to concentrate urine at collecting duct (final step in nephron)
Apoproteins attach to outside of globules; these move to Golgi and are released into interstitial fluid via exocytosis as chylomicrons --->most go to lacteal system

39. examples of different cavities... (compartments for viscera)
Most absorption occurs in sm intestine
Arrested at primary oocyte; hypothalamus GnRH->FSH released at puberty stims granulosa cell development; granulosa secrete zona pellucida = primary follicle
Signal picked up by sensory cell - goes thru dorsal root ganglion to SC - may continue to interneurons in brain or simple reflex arc in SC - brain integrates info and decides (voluntary) response - travels back down SC to appropriate ventral root gan
pericardial cavity - pleural cavity (contains lungs) - peritoneal cavity (abdominal)

40. position of AP...
Below hypothalamus
Comes into play in the large intestine - where vitamin b12 is absorbed w/help of E. coli; thus; must travel thru bloodstream to large intestine
'The hepatic portal vein is not a true vein - because it does not conduct blood directly to the heart. It is a vessel in the abdominal cavity that drains blood from the gastrointestinal tract and spleen to capillary beds in the liver.'
PNS- Somatic - afferent (dorsal root ganglion) + efferent (ventral horns) PNS- ANS- afferent (sensors on viscera) + SYMP - PARA pre - post - ganglionic neurons

41. liver and blood glucose...
**only para effectors have muscarinic receptors; symp effectors are adrenergic (epi - norepi); **neuromuscular junction uses nicotinic receptors
FAT=9 cal per gram Carbs=4.5 cal per gram - Prot=4 cal per gram - these seem to be for anhydrous forms
Liver is the control center for blood glucose; is fed by portal vein from sm intest
Estradiol (estrogen - steroid horm); prepares uterine wall for pregnancy; just before ovulation - release of estradiol stims LH in pos feedback

42. FLAT PG: FSH
Micelles; micelles transport lipase products to enterocytes for absorption at brush border
Lysosome
Nourishes follicle growth; stimulates granulosa cell growth around primary oocyte at puberty = primary follicle; also - stimulates Sertoli cells in males
RBCs - large proteins; What does enter is called the filtrate

43. Where do pancreatic secretions take effect
Peptide; responsible for luteal surge (driven in part by LH-->testosterone -->estradiol -->LH positive feedback); results in ovulation (follicle bursting) - releasing egg into fallopian tube/oviduct
On the chyme exiting the stomach and entering duodenum thru the pyloric sphincter
Transfer signals from neuron - neuron; 90% of neurons are interneurons
SYMP: spinal cord --->paravetebral ganglion PARA: spinal cord - brain; cell processes --->ganglion near effector organ (preganglionic neurons) extend outside of spinal cord to synapse at ganglia - go on along postganglionic neurons

44. Between meals most fats appear in blood as
Moves thru lymph sys; emptied into large veins (thus into bloodstream) of the neck at Thoracic duct
Prophase I: crossing over occurs; nuclear envelope is absorbed into ER; chromosomes condense)
Lipoproteins; albumin carries free fatty acids when fat is mobilized from adipose tissue - etc
AAs enter bloodstream for uptake by all cells (esp liver). If intracellular prot conc is at max AAs can be converted to fats or glucose via gluconeogenesis. Byproduct of gluconeo is ammonia --->urea.

45. Gastrulation: ectoderm/mesoderm/endoderm
Lysosome
In liver (RBC recycling of heme); stored in gall bladder; released via cystic duct to common bile duct (shared w/liver); common bile duct joins up with panc duct...everything feeds into the sm intest at the ampulla of vater**
- parietal cells (**oxyntic= hi oxygen consumption - hi E??): have hi conc mito; need lots of energy to create proton gradient; thus - responsible for extremely harsh pH conditions in stom; denaturing conditions - chief cells (peptic): synthesize pep
Ectoderm: outer coverings - nervous system Mesoderm: between covering ie musc - bone - etc - endoderm: digestive tract - viscera

46. What does peroxisome do
Steroid; target tissue is distal convoluted tubule of nephron and collecting duct; increases blood mineral concentration; potassium - protons secreted (blood pH increases); sodium - chloride reabsorbed (BP increases)
Growth 1 (G1) phase: STRUCTURAL ProteinS - ENZYMES; This is a very active period - where the cell synthesizes its vast array of proteins - including the enzymes and structural proteins it will need for growth. In G1 stage each of the chromosomes cons
Oxidizes macromolecules; breaks down very long - chain FAs by beta - oxidation; products (acetyl - CoA) are shuttled to mitochondrion for citric acid cycle
'The hepatic portal vein is not a true vein - because it does not conduct blood directly to the heart. It is a vessel in the abdominal cavity that drains blood from the gastrointestinal tract and spleen to capillary beds in the liver.'

47. Interaction of corpus luteum/placenta
The renal corpuscle
Development of placenta begins with implantation; eventually - by end of first trimester - placenta will replace corpus luteum and its estrogen/progest secretions
Direction of differentiation
1) by integral ion channels 2) transmitted by second messenger system

48. 3 phases of menstrual cycle
Most absorption occurs in sm intestine
Amino acid monomers - di - tri absorbed by symport at enterocyte; each AA has slightly diff mechanism; from entero - AAs enter bloodstream where they are taken up by all cells of the body - esp the liver by active or facilitated transport (NEVER PASS
Chylomicrons are much bigger
Follicular phase: primary - secondary - ovulation (1 week) luteal phase: ovulation - thickening of uterine lining w/corpus luteum secretion - corpus luteum degrades (2 weeks) flow: shedding of uterine lining (4 days)

49. Epithelium of the sm intestine: enterocytes lined w/brush border (digestion/absorption); goblet cells (mucous); crypts of Lieberkuhn exocrine glands (lysozyme)
Contain rough ER and Golgi to make mucous; mucous is full of **glycoprots (sticky) and electrolytes*; protects epithelial tiss of stomach from low pH and lubricates stomach
Salivary amylase; both hydrolyze glycosidic linkages
Increases blood Calcium
Know that 90% digestion - absorption occurs in sm intestine --> fine breakdown of carbs - fat - prots

50. ligands are the messenger compounds that target secondary messenger systems on effectors
Beta cells
Many modern drugs are ligands for GPCRs
Below hypothalamus
Excretes waste products: urea - uric acid - ammonia - phosphate - maintains homeostasis: including body fluid volume (water reabsorption) and solute composition (mineral balance - nutrient reabsorption) - controls *plasma* pH: antiport of Na/K and pr

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