Test your basic knowledge |

Microbiology

Instructions:

Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can study here.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. In the chlamydiae replication cycle - what undergoes binary fission and where
Reticulte body - in cytoplast of host
E. coli - shigella - salmonella - yersinia - klebsiella - proteus - enterobacter - serratia - vibrio - campylobacter - helicobacter - pseudomonas - bacteroides
Salpingitis
Antigen in urine

2. PNA in CF - burn
Pseudomonas
red algae make
motility of bacteria
Neisseria

3. This infxn causes rash - lymphadenopathy and arthritis in the mom and PDA (or pulmonary artery hypolplasia) - cataracts and deafness +/- blueberry muffin rash - org and transmission
Chronic monoarthritis and migratory polyarthritis
oxygen requirements of bacteria
Resistant to destruction by heat or chemicals - need to autoclave to kill by steaming at 121C for 15 minutes
Rubella - respiratory droplets

4. What does poxvirus cause

Warning: Invalid argument supplied for foreach() in /var/www/html/basicversity.com/show_quiz.php on line 183

5. What is the organism and histological findings for ehrliciosis
Black necrosis surrounded by edematous ring - caused by letha factor and edema factor
malaria symptoms
Ehrlichia: no rash - granulocytes with berry cluster organisms
Transcribe negative strand to positive - RNA dependent RNA polymerase

6. What shape are campylobacter and What are the lab findings
Comma shaped - s - shaped - oxidase positive - grows at 42 C
what many pathogenic fungi are
Cleaves host cell rRNA (inactivates 60S ribosome) - also enhances cytokine release causing HUS - shigella and E. Coli 0157:H7
Roseola - high fevers for several days that can cause seizures - followed by a macular papular rash - not determined

7. What is chlamydia trachomatis - tricky Ts
Bacteria - STD
Visceral leishmaniasis - donovani - sandly - macrophages containing amastigotes (lack flagella) - sodium stibogluconate
Cryptosporidium - mycobacterium avium - intracellulare - CMV colitis - non Hodgkin lymphoma from EBV - Isospora belli
B cells

8. Unimmunized child with fever - dysphagia - drooling - and difficulty breathing due edematous cherry red epiglottis
Epiglottitis H flu type B
Active hepatitis - cirrhosis and HCC
Rifampin
Trigeminal and dorsal root ganglia

9. What is the fever cycle for p. vivax/ovale
Sterility
Cycles occur every other day: dormant form in liver
SHiN - strep pneumo - h flu - neisseria
HIV - AIDS

10. ___ of cancers are known to be _____ induced
Beta hemolytic
10%; viral
Cough - coryza - conjunctivitis
Negative

11. What are agryll roberston pupils
Accommodate but does not react - associated with tertiary syphillis
Owl's eye inculsions
HBV (antigen = recombinant HBsAg) HPV (6 - 11 -16 -18)
Enterotoxins - TSST-1 - exfoliatin which causes scalded skin syndrome

12. What animals carry rabies virus
Babesiosis - ixodes - blood smear - quinine and clindamycin
Bat - racoon - skunk
Antiphagocytic virulence factor
special staining of bacteria

13. What bug grows on sabouraud's agar
Fungi
Azithromycin
Bad xray - worse than pt - high titer of cold agglutinins (IgM) which can agglutinate or lyse RBCs - grown on Eaton's agar
Azithromycin

14. What is S. aureus food poisoning due to...
Fimbriae - cystitis and pyelonephritis; K capsule - pneumonia - neonatal meningitis - LPS endotoxin - septic shock
John Needham - experiment
gram- positive stain - explanation
Ingestion of preformed toxin

15. What bug grows on thayer - martin (or VPN) media - What does VPN stand for
release (B)
candidiasis
N. gonorrhea - vancomycin (inhibits gram pos) polymyxin (inhibits gram neg) - nystatin (inhibits fungi)
Motility - protein

16. SIV does not infect humans - HIV does
<30 - military - prisons
virus example
ADP- R AB toxin - inactivates EF-2; causes pharyngitis and pseudomembrane in the throat (similar to pseudomonas exotoxin A)
Type B protease IgA

17. Which nematodes are ingested
N. meningitidis - enterovirus - s pneumo - HSV
Eastern equine virus - wesetern equine virus - rubella not
red algae make
Enterobius - ascaris - trichinella

18. trypanosoma - tricky Ts
Protozoan - causes chagas dz - or african sleeping sickness
M. kansasii
Visceral leishmaniasis - donovani - sandly - macrophages containing amastigotes (lack flagella) - sodium stibogluconate
B cells - fever hepatosplenomegaly - pharyngitis - lymphadenopathy

19. What are the markers of Hep immunity
cell wall - function
Anti - HBsAb
A second - different antigenic determinant of the HBV core - HBeAg indicates active viral replication and therefor high transmissability
Parvoviridae

20. What is the fxn and chemical composition of the outer membrane in gram negative bacteria
Antigen found on the surface on HBV - indicates hepatitis B infection
Site of endotoxin (LPS) - major surface antigen - lipid A induces TNF and IL-1 - polysaccharide is the antigen
Anti - HAVAb IgM
chromosomes in nucleus are...

21. How is legionella detected clinically
Chronic disease - positive during window period
microbiology
Antigen in urine
Icterohemorrhagic leptospriosis - sever form with jaundice and azotemia from liver and kidney dysfxn - ; fever hemorrhage and anemia

22. What are the viral causes of meningitis
Enterovirus esp coxsackievirus - HSV - HIV - West Nile virus - VZV
Burn wounds - nosocomial pneumonia - pneumonias in cystic fibrosis
Acsaris lumbricoides (giant roundworm) - bendazole or pyrantel pamoate
Specialized transduction - an excision event

23. Motility causes 'swarming' on agar - produces urease - associated with struvite stones - org causing UTI
Proteus mirabilis
Heterophil antibodies detected by agglutination of sheep RBCs
Antiphagocytic virulence factor
Lymph nodes

24. What are the 3 C's for measles
Cough - coryza - conjunctivitis
Protein A - S. aureus
Haemophilus ducreyi - chancroid
microbiology

25. Ringworm - athlete's food - jock itch
fungal infection examples (3)
L1 - L2 - L3
Transformation or competence
H flu

26. Helical - polyhedral - complex
viral shapes
HBsAg as envelope - can coinfect or superinfect (worse prognosis)
Pseudomonas
chloroplasts - function

27. What are koplick spots - and when/How does the rash present in measles infxn
S. aureus
Red spots with blue/white center on buccal mucosa - rash presents last - spreads from head to toe and includes hands and feet (vs. truncal rash in rubella)
Between 2 and 18 months
Coagulation cascade - DIC

28. What does HDV require and What are the possible infxns it can cause
protozoology
HBsAg as envelope - can coinfect or superinfect (worse prognosis)
Lymph nodes
Rotavirus - dsRNA reovirus - villous destruction with atrophy leads to dec absorption of Na and H2O - day care centers and kindegartnes

29. What happens when primary TB heals by fibrosis
Immunity and hypersensitivity - tuberculin positive
Klebsiella
Candidal esophagitis - toxoplasmosis - histoplasmosis
species

30. Lowercase/italics or underlined
Fever - malaise leading to agitation - photophobia - hydrophobia leading to paralysis - coma and death
species
Group B strep - E. coli - listeria
arrangements - staphylo

31. What organisms stain with india ink
Blocka glycine and GABA release - inhibitory NTs from Renshaw cells in spinal cord
Cryptococcus neoformans
coccus
Group B strep - E. coli - listeria

32. Lyme dz - ixodes tick that lives on deer and micd
Fungi (pneumocystis) - legionella
flaccid paralysis
L1 - L2 - L3
Borrelia burgdorferi

33. 10 - 100 micrometers
Dipicolinic acid
some fungi produce ______ that are toxic to humans
eukaryotes
Topocal miconazole - selenium sulfide

34. meningitis from 6 -60 yrs
osmotic lysis
N. meningitidis - enterovirus - s pneumo - HSV
Chronic disease - positive during window period
H. flu type B - meningococcal vaccines

35. What does polyomavirus cause
HBV
Viridans group streptococci
JC - progressive mutlifocal leukoencephalopathy in HIV
Haematobium - bladder

36. What is the TX for h pylori
Triple therapy - metronidazole - bismuth - either tetracycline or amoxicillin OR metro - omeprazole and clarithromycin
Lepromatous - diffusely over skin and is communicalbe (immunoCised) tuberculoid limited to a few hypoesthetic skin nodules (immunoCtent
Coccidiodiomycosis - southwestern US - CA - San Joaquin Valley valley fever - spherules
Pyelonephritis - fever - chills flank pain - CVA tenderness - hematuria and WBC casts

37. What kind of virus is HCV and How is transmitted
Ceftriaxone - rifampin for close contacts
S. pneumo - klebsiella - staph
RNA flavivirus - transmitted primarily via blood and resembles HBV in its course and severity
Rotavirus - dsRNA reovirus - villous destruction with atrophy leads to dec absorption of Na and H2O - day care centers and kindegartnes

38. Where do CMV cells remain latent
IL-1 - lever - TNF - fever/hemorrhagic tissue necrosis - NO - hypotension
Mononuclear cells
Tellurite agar
KS from HHS-8 - invasive cervical caricoma from HPV - and primary CNS lymphoma - non - Hodgkin's lymphoma

39. Which DNA viruses are not linear
Reactivation HSV - cyrptosporidious - isospora - disseminated coccidioidomycosis - pneumocystis PNA
Papilloma - polyoma (circular - supercoiled) and hepadna (circular incomplete)
Trigeminal ganglia
CNS - parenchmal tuberculoma or meningitis - vertebral body (pott's disease) - lymphadenitis - renal - GI

40. 1 - 10 micrometers
Trigeminal ganglia
Comma shaped - oxidase positive - grows in alkaline media
Protozoan - a TORCH infection
prokaryotes

41. What doe HBV and HCV infxn predispose to...
replication for eukaryotes
S. pneumo - H. flu - Anaerobes - viruses - mycoplasma
Active hepatitis - cirrhosis and HCC
Mycoplasma

42. What is in pneumovax
Chronic monoarthritis and migratory polyarthritis
Tumbling motility - meningitis in newborns - unpasteurized milk
C. trachomatis - subactue - often undiagnosed - N. gono - acute with high fever; C. trachomatis is the most common STI in the US
H. flu type B - meningococcal vaccines

43. Tetanus - toxin prevents relaxation of muscles
actinomycetes (3) - description
Metronidazole
Clostridium tetani
8 segments of neg stranded RNA undergo high frequency recombinatino via reassortment

44. What can cause food poisoning in meat - maynaisse custard with pre - formed toxin
adsorption (AV)
chemical synthesis...
S. aureus
Pseudomonas

45. What is toxic shock syndrome - what bug secretes what substance to cause it
viral shapes
Syphillis - sexual contact
Clue cells - or vaginal epithelial cells covered with bacteria visible under the microscope
Fever - rash - shock - S aureas - TSST-1

46. Why are chlamydiae obligate intracellular

Warning: Invalid argument supplied for foreach() in /var/www/html/basicversity.com/show_quiz.php on line 183

47. Segment of DNA that can jump from one location to another - can transfer genes from plasmid to chromosome and vice versa
arrangements - staphylo
Transposition - some flanking genes can be gained and lost - and transferred in conjugation
Encapsulated or not - positive if encapsulated bug is present; capsule swells when specific anticapsular antisera are added
some fungi produce ______ that are toxic to humans

48. Structure unique to some bacteria
Catalase pos organisms - remove H2O2 leading to infection - staph
cell wall - function
endospores
gram- negative stain - explanation

49. What kind of genome does HIV have
Dipoid RNA
Naegleria fowleri - freshwater lakes through cribiform plate - amoebas in spinal fluid - amphotericin for survivors
Hodgkin lymphoma - endemic Burkitt lymphoma - nasopharyngeal carcinoma
15-20 - atypical lymphocytes

50. What kind of lesion is characteristic of secondary pulmonary tuberculosis
Fibrocaseous cavitary lesion in upper lobe
Pox - complex
Lepromatous
five kingdoms of microorganisms