Test your basic knowledge |

Microbiology

Instructions:

Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can study here.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. What often causes infection with C. diff and How is it dx
Retrovirus - togavirus - flavivirus - coronavirus - hepevirus - calicivirus - picornavirus
CMV - sexual contact - organ transplants
three domains of microorganisms
Often secondary to Abx use - diagnosed by detection of one or both toxins in the stool

2. What does papillomovirus cause
Koch's Postulates 4
HPV - warts (1 - 2 - 6 - 11) - CIN - cervical cancer (16 - 18) vaccine available
Mycoplasma - legionella - chlamydia
Mycoplasma - have sterols

3. Spaghetti and meatball appearance on KOH prep - dz - organism
Salmonella
Preallergic lymphatic or hematogenous dissemination - reactivation in adult life
HPV 6 and 11 - condylomata acuminata
Tinea versicolor - malassezia furfur

4. Pure culture must cause same disease in test host

Warning: Invalid argument supplied for foreach() in /var/www/html/basicversity.com/show_quiz.php on line 183

5. urethritis - cervicitis - conjunctivits - Reiters syndrome - PID - org and dz
Chlamydia trachomatis (D- K) - chlamydia
HBsAg as envelope - can coinfect or superinfect (worse prognosis)
S. pyogenes - hemolysin antigen for ASO antibody Which is used in the dx of rheumatic fever
ImmunoCised - or their close contacts

6. 'powerhouse of the cell' - involved with ATP (energy) productions; contain 70S ribosomes
penetration (B)
mitochondria - function
Lower lobe
biggest danger of toxplasmosis

7. What protozoa can cause watery diarrhea
Giardia and crytosporidium in immunoCised pts
Mycoplasma - legionella - chlamydia
Protozoan - a TORCH infection
eukaryotic organelles (5)

8. Describe the rabies virus
smooth ER
Virbrio cholera
Comma shaped - oxidase positive - grows in alkaline media
Bullet shaped capsid - long incubation period before sx onset

9. What happens in tertiary syphillis
Only borrelia
Antibody to HBsAg - indicates immunity to hep B
Gummas (chronic granulomas) - aortitis (vasa vasorum destruction) neurosyphillis (tabes dorsalis) - argyll robertson pupils
eukaryotes

10. Osteomyelitis in diabetics and drug addicst
fimbriae - function
Pseudomonas
Lepromatous - diffusely over skin and is communicalbe (immunoCised) tuberculoid limited to a few hypoesthetic skin nodules (immunoCtent
Subcutenous plaques - polyarthritis - erythema marginatum - chorea - carditis - no 'rheum' for SPECCulation

11. What is the mechanism of renal failure and thrombocytopenia in HUS
CMV retinitis and esophagitis - disseminated M avium intracellulare - cryptococcal meningoencephalitis
bacteria domain
Endothelium swells and narrows lumen - leading to mechanical hemolysis and reduced renal blood flow - damaged endothelium consumes platelets
Mycoplasma - legionella - chlamydia

12. What is the only live attenuated vaccine that can be given to HIV pos pts
When nutriets are limited
Acute or chronic - vaccine is HBsAg - reverse transcriptase though not a retrovirus
spiral - spirillum
Measles - mumps - rubella - MMR

13. Enzyme that helps destroy cell walls
how do viruses take over a host cell?
lysozyme
LCMV - lymphocytic choriomeningitis virus - Lassa fever encephalitis - spread by mice
Klebsiella

14. What does reverse transcriptase do in HIV
Antigen found on the surface on HBV - indicates hepatitis B infection
Synthesized dsDNA from RNA; dsDNA integrates into host genome
Borrelia - leptospira - treponema
Aminoglycoside plus extended spectrum pen (pipercillin - ticarcillin)

15. What disease can HSV 2 cause and What is the route of transmission
Diaper rash - endocarditis in IVDU - disseminated candidiasis - chronic mucocutanous candidiasis
Herpes genitalis - neonatal herpes - sexual contact - perinatal
Infectious = most of dsDNA (not pox/HBV) (+) strand ssRNA (same as mRNA); non infecitious = (-) ssRNA - dsRNA
Generalized transduction - a packaging event

16. Transmitted by ticks - flulike symptoms with spotted rash; damages cardiovascular system and affects permeability of capillaries resulting in spotted rash
what peptidoglycan is composed of
L1 - L2 - L3
protista kingdom
Rocky Mountain Spotted Fever

17. What is the fxn and chemical composition of the bacterial ribosome
Water source - endotoxin causing fever and shock - exotoxin A (inactivates EF-2)
gram- negative stain - explanation
Protein synthesis - 30S and 50S subunits
No cell wall

18. What are the assiaction of pseudomonas and What can it cause

Warning: Invalid argument supplied for foreach() in /var/www/html/basicversity.com/show_quiz.php on line 183

19. Ringworm - athlete's food - jock itch
CMV
fungal infection examples (3)
golgi complex - function
ribosomes (eukaryotic) - size

20. This fungi can be found in bird/bat droppings or within macrophages and causes pneumonia - Where is it endemic
Salpingitis - endometritis - hydrosalpinx - tubo - ovarian abscess; can lead to Fitz - High - Curtis sydnrome - infectino of liver capsule and violin string adhesions of parietal peritoneum to liver
Borrelia - plasmodium - tryapanosomes - chlamydia
Histoplasmosis - mississippi and ohio river valley
Strongyloides stercoralis - larvae penetrate skin - bendazoles or ivermectin

21. What are the gram pos bacilli
Traveler's diarrhea - labile toxin/stable toxin - no inflammatino or invasion
35 to 37 weeks - intrapartum pen prophylaxis
Clostridium - cornybacterium - bacillus - listeria - mycobacterium (acid fast)
Robert Hooke

22. Water movement with hypotonic solution or hypertonic solution
Oral thrush - tinea pedis - reactivation VZV - reactivation TB - bacterial infxns (H flu - S pneumo - Salmonella)
Streptococcus - staphylococus
Retrovirus - togavirus - flavivirus - coronavirus - hepevirus - calicivirus - picornavirus
osmotic pressure

23. Who mostly gets infected with leptospira
Children
Cell Theory
Surfers in the tropics
five fields of microbiology

24. What kind of temperatures do m. leprae like - What tissues do they infect - and What is the resevoir in the US
Crohns or appendicitis
C. trachomatis (L1- L3) - lymphgranuloma venereum
Cool temps - infects skin and superficial nerves - armadillos
Pets - treat with topical azoles

25. What species producing watery diarrhea produce St and LT toxins - and is the main cause of travelers diarrhea
Mucor or rhizopus
Entertoxigenic E. coli
Rubella german measles
Protozoan - causes chagas dz - or african sleeping sickness

26. Bacillus - coccus - and spiral
Beta hemolytic
Rose gardner's
basic shapes of bacteria
E. coli - proteus

27. This infxn causes rash - lymphadenopathy and arthritis in the mom and PDA (or pulmonary artery hypolplasia) - cataracts and deafness +/- blueberry muffin rash - org and transmission
60%; viruses
Motility - protein
Rubella - respiratory droplets
Syphillis - sexual contact

28. Which are the naked viruses
Congenital infection - mononucleosis with negative monospot - pneumonia - congenital - transfusion - sexual contact - saliva - urine - transplant
Calicivirus - picornavirus - reovirus - parvovirus - adenovirus - papilloma - polyoma
Mediates adherence to surfaces - especially foreign surfaces like indwelling catheters; polysaccharide
Comma shaped - oxidase positive - grows in alkaline media

29. Locomotion by rotation of basal body
flagella - function
mycology
Pasteurella multocida
Cholesterol

30. Study of bacteria
bacteriology
Silver stain
S. pneumo - klebsiella - staph
Actinomyces

31. What color sputum - and sepsis in which patients is associated with pneumococcus
uncoating (AV)
Rusty sputum - sepsis in sickle cell after splenectomy
Aminoglycoside plus extended spectrum pen (pipercillin - ticarcillin)
ribosomes (eukaryotic) - size

32. Allows attachment of bacteria to surfaces
fimbriae - function
five nutritional adaptations of fungi compared to bacteria
Transfer of just plasmid in F+ and transfer of plasmid plus some flanking genes in Hfr x F-
Campylocobacter jejuni

33. Cellulitis - osteomyelitis from animal bite: cats and dogs
microbiology
Foul smelling (short chain fatty acids) - difficult to culture - produce gas in tissues (CO2 - H2)
assembly (B)
Pasteurella multocida

34. A waxy substance that retains carbolfuchsin
mycolic acid - definition
Guillain barre
Elevated CRP and ESR
infection process of bacteriophage (5)

35. What is the TX for candidiasis
Group B are resistant - group A are sensitive - B- BRAS
Parvovirus B19 and erythema infectiosum
Nystatin for superficial - ampho B for systemic
S. aureus

36. In which age group is the peak incidence for mononucleosis - and how are the reactive cytotoxic T cells termed?
Entertoxigenic E. coli
S. aureus - Strep pyogenes - group B strep - listeria monocytogenes
15-20 - atypical lymphocytes
Retrovirus - togavirus - flavivirus - coronavirus - hepevirus - calicivirus - picornavirus

37. What are neoplasms associated with HIV

Warning: Invalid argument supplied for foreach() in /var/www/html/basicversity.com/show_quiz.php on line 183

38. What does rubeloa virus cause
gram- positive cell wall
Measles - koplik spots on buccal mucosa are diagnostic
single- stranded RNA
Topocal miconazole - selenium sulfide

39. What s. aureus infection is an imporant cause of serious nosocomial and community- acquired infections
facultative
Mice - deer
Robert Koch
MRSA - resistant to beta lactams due to altered penicillen binding protein

40. Which bacteria grow pink colonies on MacConkey's agar
Loa loa - deer/horse/mango fly - diethylcarbamazine
Wuchereria bancrofti - femile mosquito - 9 months to 1 year after bite to develop symptoms - diethylcarbmazine
Echinococcus granulosus
Lactose fermeting enterics - citrobacter - klebsiella - E. coli - enterobacter - serratia

41. What is the treatment for c. diff infection
Metronidazole
No envelope
Superantigen that binds MHCH II and T cell receptor resulting in poly colonal T cell activation
what many pathogenic fungi are

42. Which are the RNA enveloped viruses
rough ER
Hemagluttin
Influenza virus - parainfluenza virus - RSV - measles virus - mumps virus - rubella virus - rabies virus - HTLV - HIV
Pneumocystis jerovici

43. Viruses are not considered living; they need to be in a cell; and they do not grow on artificial media

Warning: Invalid argument supplied for foreach() in /var/www/html/basicversity.com/show_quiz.php on line 183

44. What is the fxn and chemical composition of the bacterial glycocalyx
Dipoid RNA
Trypanosoma bruceii - tsetse fly (painful bite) - blood smear - suramin for blood borne - melarsoprol for CNS infxn
Spongiform encephalopathy and dementia - ataxia and death.
Mediates adherence to surfaces - especially foreign surfaces like indwelling catheters; polysaccharide

45. Will show special structures
Mold with irregular nonseptate hyphae branching at wide angles
special staining of bacteria
Aerosal - from environmental water source
Macrophages - complement pathway and hageman factor

46. What is HBcAg
Antigen associated with core of HBV
Treponema - primary syphillis
they are eukaryotes
Lymph nodes

47. What are the 3 structural proteins coded for by the HIV genome
Env - gp120 and gp41 - gag - p24 - pol - reverse transcriptase
Candidal esophagitis - toxoplasmosis - histoplasmosis
single- stranded DNA
All of them

48. Bugs in hospital acquired PNA
Lazzaro Spallanzani
Onchocerca volvulus - female blackfies - ivermectin
Staph or enteric GNR
Reverse transcriptase - HIV - HTLV - T cell leukemia

49. Circular and haploid - only one per cell - no nucleus
infection process of animal viruses (6)
chromosome - description
Smallpox - although eradicated - could be used in germ warfare Vaccinia - cowpox 'milkmaid's blisters' Molluscum contagiosum - flesh colored dome lesions with central dimple
Thursh - HSV - CMV - oral hairy leukoplakia from EBV

50. Can grow with or without oxygen but prefers oxygen
Invasive - dysentary - shiga like toxin; microbe invades mucosa and toxin causes necrosis and inflammation
HBV
Rabies - influenza - salk polio - HAV
facultative