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Test your basic knowledge |
Microbiology
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Study First
Subject
:
engineering
Instructions:
Answer 50 questions in 15 minutes.
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study here
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Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Trichomonas
dormant
glycocalyx - description
Enterobius
flagella
2. What is the technique to visualize treponema
Often secondary to Abx use - diagnosed by detection of one or both toxins in the stool
Darkfield microscopy and fluoresecent
Cytoplasm - except influenza and retroviruses
Histoplasmosis
3. 80S = 60S + 40S
ribosomes (eukaryotic) - size
Lynn Margulis - gen. information
Dysuria - frequency - urgency - suprapubic pain - WBCs but not casts in urine
Meningococci
4. Rod- shaped
Toxocara canis - food contaminated with eggs - diethylcarbamazine
E. coli
bacillus
Anemia - thrombocytopenia - acute renal failure
5. How does mucomycosis present clinically
Synthesized dsDNA from RNA; dsDNA integrates into host genome
Chronic disease - positive during window period
Mostly in DKA pts and leukemic pts - rhinocerebral - frontal lobe abscesses - HA - facial pain - black necrotic eschar on face - cranial nerve involvement
Adults - preformed toxin - babies - ingestion of spores in honey
6. Ability to move via flagella
B anthracis - anthrax - cutaneous is black eschar ulcer (painless) can progress to bacteremia or death - pulmonary anthrax is inhalation of spores producing flu - like sx that rapidly progress to fever pulmonary hemorrhage - mediastinitis and shock
Clostridium perfringens
Specialized transduction - an excision event
motility of bacteria
7. Brain abscesses in HIV - classic triad of chorioretinitis - hydrocephalus - intracranial calcifications - dz - transmission - dx - and tx
Toxoplasma - cysts in meat or cat feces - serology/biopsy - sulfadiazine + pyrimethamine
Febrile pharyingitis - acute hemorrhagic cystitis - pneumonia - conjunctivitis (watery)
botulism
Lower lobe
8. When is H flu vaccine give
antibiotics
Croup - seal like barking cough
Congenital infection - mononucleosis with negative monospot - pneumonia - congenital - transfusion - sexual contact - saliva - urine - transplant
Between 2 and 18 months
9. African sleeping sickness: enlarged lymph nodes - recurring fever - organism - transmission - dx - tx
Chlamydia trachomatis (D- K) - chlamydia
Trypanosoma bruceii - tsetse fly (painful bite) - blood smear - suramin for blood borne - melarsoprol for CNS infxn
Viridans is resistant and pneumo is sensitive - OVRPS (overpass)
Pets - treat with topical azoles
10. What enzyme breaks down lactose and Which bacteria produces it
Chagas dz - trypanosoma cruzi - reduviid bug - blood smear - nifurtimox
E. Coli produces beta galactosidase
Rubella - respiratory droplets
Allergic bronchopulmonary aspergillosis - lung cavity aspergilloma 'fungus ball' invasice aspergillosis in immunoCised pts and those with chronic granulomatous disease
11. This bacteria is a majore cause of bloody diarrhea - esp in children - fecal - oral transmission through mean (poultry - met unspasteurized milk
HSV1 and 2 - VZV - CMV - EBV
Genetic shift - pandemic
Campylocobacter jejuni
Protein A - S. aureus
12. Host cell usually lyses - lysozyme produced
Aureus does - epidermidis and group B do not
spiral - spirochete
PCR/Viral load
release (B)
13. What kind of exotoxin does V. cholerae have and What does it do
Schistosoma - snail - cercariae penetrate skin of humans - praziquantrl
Antiphagocytic virulence factor
ADP ribosylation of G protein stimulates adenylyl cyclase - inc Cl - secretion into gut and dec Na absorption - H20 into gut lumen - voluminous rice water diarrhea
Dipoid RNA
14. Obligate intracellular parasites - most can infect cells of only one host species
Meningitis - waterhouse friderichsen -
Campylobacter
viruses
HIV - malnutrition - death
15. What are the symptoms of TB
Fusion and entry
Ferver - night sweats - weight loss - hemoptysis - can be drug resistant
Type B capsular polysaccharide conjugated to diptheria toxoid or other protein
facultative
16. Helical - polyhedral - complex
viral shapes
Ancylostoma duodenale - necator americanus - larvae penetrate skin of feet - bendazoles or pyrantel pamoate
Retrovirus - togavirus - flavivirus - coronavirus - hepevirus - calicivirus - picornavirus
Plasma membrane - exceptions are herpesvirus which acquire from nuclear membrane
17. tissue nematode causing skin inflammation and ulceration - org - transmission - tx
Animal - except typhi - only in humans
golgi complex - function
Dracunculus medinensis - in drinking water - niridazole
Sporothrix schenckii
18. What is the source of pseudomonas and What does virulence factors does it have
Water source - endotoxin causing fever and shock - exotoxin A (inactivates EF-2)
single- stranded DNA
HBC - hepatitis B
osmotic lysis
19. Which staph make coagulase - and which don't
CMV retinitis
Mycobacterium avium intracellulare
Aureus does - epidermidis and group B do not
Microbes that may pass from mother to fetus - hepatosplenomegaly - jaundice - thrombocytopenia - growth retardation
20. What is the treatment for meningitis from H flue
Meningococci
rough ER
Rapid antigenic variation of pilus proteins
Ceftriaxone - rifampin for close contacts
21. 37 celsius
Bat - racoon - skunk
Parvoviridae
Cytoplasmic inclusions seen on giemsa stain or fluorescent antibody- stained smear
how many degrees celsius for yeast?
22. What kind of microbes cause recurrent infections in patients with chronic granulomatous disease and why
Catalase pos organisms - remove H2O2 leading to infection - staph
HHV-6 roseola
hypertonic solution
Anemia - thrombocytopenia - acute renal failure
23. Diplo - staphylo - strepto
Contains a variety genes for antibiotic resistance - enzymes and toxins; DNA
Group B are resistant - group A are sensitive - B- BRAS
Group B strep
arrangements of bacteria
24. ___ percent of infected illnesses are caused by ___
not acid- fast - colo
Serratia
60%; viruses
Lynn Margulis - gen. information
25. trematodes causing granulomas - fibrosis - inflammation of spleen and liver - org - host - transmission - tx
Schistosoma - snail - cercariae penetrate skin of humans - praziquantrl
ribosomes (eukaryotic) - size
Actinomyces
Rifampin
26. What OI/disease occurs in the mouth and throat of AIDS pts
Thursh - HSV - CMV - oral hairy leukoplakia from EBV
Transformation or competence
Neuraminidase
Pseudomonas
27. What is the nl flora of a dental plaque
Streptococcus mutans
ALT > AST in viral - AST > ALT in EtOH
food industry
Cytoplasm - except influenza and retroviruses
28. Require intracellular parasite/has to be within a host cell to replicate (prokaryotic); causes trachoma (most common infectious cause of blindness in the world)
C3a - hypotension - edema and C5a - neutrophil chemotaxis
Papilloma - polyoma - hepadnavirus
biogenesis
chlamydia
29. Which bacteria make catalase and which do not
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30. What are the ToRCHeS infxns and What are the nonspecific signs common to ToRCHeS infxns
Microbes that may pass from mother to fetus - hepatosplenomegaly - jaundice - thrombocytopenia - growth retardation
Malignant otitis externa
Antigen associated with core of HBV
Mucor or rhizopus
31. What is the treatment for syphillis
Pen
Owl's eye inculsions
spiral - vibrio
monera kingdom
32. trypanosoma - tricky Ts
Protozoan - causes chagas dz - or african sleeping sickness
Pseudemonas aeruginosa
Owl's eye inculsions
Ceftriaxone - rifampin for close contacts
33. Bugs in hospital acquired PNA
Rusty sputum - sepsis in sickle cell after splenectomy
Reverse transcriptase - HIV - HTLV - T cell leukemia
Staph or enteric GNR
Posterior cervical lymph nodes
34. what bug grows pink colonies on MacConkey's agar
bacteria domain
helical shape - definition
Lactose fermenting enterics
Mycobacterium
35. What are koplick spots - and when/How does the rash present in measles infxn
Red spots with blue/white center on buccal mucosa - rash presents last - spreads from head to toe and includes hands and feet (vs. truncal rash in rubella)
When nutriets are limited
chemical synthesis...
Enterobius
36. Fungal infections can be hard to get rid of because
microbiology
Yersinia pestis
they are eukaryotes
Rapid cell division
37. Which bacteria are beta hemolytic
Bacterial superinfection
mycoplasma (5) - description
Actinomyces
S. aureus - Strep pyogenes - group B strep - listeria monocytogenes
38. What drug is used in RSV to neutralize F protein
chlamydia
Toxoplasmosis
Palivizumab
Severe bacteremia - death
39. What is seen on with the dermatophytes with KOH prep
Mold hyphae - not dimorphic
N. gono causing gono
Koch's Postulates 4
E. Coli
40. Locomotion or can move substances along the cell
Cleaves host cell rRNA (inactivates 60S ribosome) - also enhances cytokine release causing HUS - shigella and E. Coli 0157:H7
Smallpox - although eradicated - could be used in germ warfare Vaccinia - cowpox 'milkmaid's blisters' Molluscum contagiosum - flesh colored dome lesions with central dimple
cilia - function
Paracoccidioidomycosis
41. Where are spores of C. botulinum found
Canned food - honey (causing floppy baby)
Rabies
Francesco Redi - experiment
Treponema - 2ndary syphillis
42. What is the organism for endemic typhus (fleas)
Pseudomembranous (grey- white membrane) pharyngitis with lymphadenopathy
glycocalyx - function
Klebsiella
R. typhi
43. This bacteria causes gastritis and up to 90% of duodenal ulcers - risk factor for peptic ulcer - gastric adenocarcinoma - lymphoma
endocytosis...
histoplasmosis
bacillus
H. pylori
44. 1876 - Germ Theory of Disease - he proved that a specific microbe causes a specific disease; proved that a bacterium caused anthrax and provided Koch's postulates
Pregnant women
Robert Koch
H. flu type B - meningococcal vaccines
Env - gp120 and gp41 - gag - p24 - pol - reverse transcriptase
45. What bugs can colonize the respiratory mucosa and why
Coxsackie A - rocky mountain spotted fever and syphillis (CARS)
S. pneumo - H. flu type b - Neisseira - SHiN - IgA protease cleaves IgA
Pseudomembranous (grey- white membrane) pharyngitis with lymphadenopathy
Pen G and vanc - may be sens to ampicillin
46. What is pontiac fever
Alpha toxin (lecithinase) that can cause myonecrosis (gas gangrene) and hemolysis
Envelope proteins
Mild flulike symptoms with legionella
B anthracis - c. perfringens - c tetani (b cereus and c botulinum also form spores
47. What bacteria has protein A and What does it do
S. aureus - virulence factor - binds Fc - IgG - inhibiting complement fixation and phagocytosis
35 to 37 weeks - intrapartum pen prophylaxis
Type B protease IgA
Permanently disables causing whooping cough via induction of cAMP - turns the off off
48. portal HTN - parasite
Thursh - HSV - CMV - oral hairy leukoplakia from EBV
Encapsulated microbes SHiN
C. diptheriae
Schistosoma mansori
49. What do you see on blood agar with C. perfringens
Gram neg rod - poor gram stain - use silver stain - grow on charcoal yeast extract with iron and cysteine
Rickettsia - legionella - chlamydia (lacks muramic acid in cell wall)
Double zone of hemolysis
Headache - fever - rash (vasculitis) - obligate intracellular that need CoA and NAD+
50. Which gram pos bacteria have branching filamentous morphology
C. trachomatis (L1- L3) - lymphgranuloma venereum
Actinomyces and nocardia (weakly acid fast)
Wound and burn infectinos - Pneumonia in CF - sepsis - external otitis (swimmer's ear) - UTI - drug use and diabetic osteomyelitis and hot tub follculitis
Congenital infection - mononucleosis with negative monospot - pneumonia - congenital - transfusion - sexual contact - saliva - urine - transplant
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