Test your basic knowledge |

Microbiology

Instructions:

Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can study here.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Look like molds - but cells are prokaryotic; have filamentous growth and some produce asexual spores; Streptomyces produces geosmin ('fresh dirt' smell) and many antibiotics
actinomycetes (3) - description
Transfer of just plasmid in F+ and transfer of plasmid plus some flanking genes in Hfr x F-
Lactose fermeting enterics - citrobacter - klebsiella - E. coli - enterobacter - serratia
Foul smelling (short chain fatty acids) - difficult to culture - produce gas in tissues (CO2 - H2)

2. painful penile - vulvar cervical vesicles and uclers - can cause systemic symptoms such as fever - HA - myalgia - org and dz
HSV-2 - genital herpes
Shingles/chickenpox - encephalitis - pneumonia - respiratory secretions
Bordetella pertussis
CAMP factor enlarges area of hemolysis formed by S. aureus

3. Postviral PNA
Common cold
CNS - parenchmal tuberculoma or meningitis - vertebral body (pott's disease) - lymphadenitis - renal - GI
Staph or H. flu
Enteroinvasive E. coli

4. What is the TX for leprosy and What is the toxicity of this TX
Does not ferment sorbitol
Dapsone - hemolysis and methemoglobinemia or rifampin and combination clofazimine + dapsone
Antibody to HBsAg - indicates immunity to hep B
humans do not have

5. What happens in stage 1 of lyme disease
Subcutenous plaques - polyarthritis - erythema marginatum - chorea - carditis - no 'rheum' for SPECCulation
commercial applications
Bulls eye rash - flulike symptoms
not acid- fast - colo

6. Protein coat surrounding nucleic acid
Capsid protein
Adults - preformed toxin - babies - ingestion of spores in honey
Wound and burn infectinos - Pneumonia in CF - sepsis - external otitis (swimmer's ear) - UTI - drug use and diabetic osteomyelitis and hot tub follculitis
capsid - definition

7. This substance binds directly to MHC II and T cell receptor simultaneously - activating large numbers of T cells to stimulate release of IFN gamma and IL-2
Meningitis - waterhouse friderichsen -
Superantigen
Serratia
viral shapes

8. What is present in the condylomata and chancres in primary and secondary syphillis
Group B strep
Actinomyces and nocardia
Pneumoniae and psittaci
Many treponemas

9. 1668 - Attempted to disprove spontaneous generation
H flu type B
Francesco Redi
algology
Tropheryma whippelii (whipple's dz)

10. Segment of DNA that can jump from one location to another - can transfer genes from plasmid to chromosome and vice versa
Comma shaped - s - shaped - oxidase positive - grows at 42 C
hyperthermophiles
lysis
Transposition - some flanking genes can be gained and lost - and transferred in conjugation

11. What are negri bodies and when are they seen
plasmid - definition
HIV - AIDS
Characteristic cytoplasmic inclusion bodies in neurons infected with rabies virus; commonly found in Purkinje cells of cerebellum
Pseudomonas

12. What is the lab diagnosis of C. dipetheria
ELISA test is sensitive but high false pos rates and low threshold - RULE OUT test - pos test are confirmed with western blot - High false neg - high threshold
Rocky Mountain Spotted Fever
Gram pos rods with metachromatic (blue and red) granules
Actic polymerization

13. What is weil's disease
B anthracis - anthrax - cutaneous is black eschar ulcer (painless) can progress to bacteremia or death - pulmonary anthrax is inhalation of spores producing flu - like sx that rapidly progress to fever pulmonary hemorrhage - mediastinitis and shock
Koch's Postulates 4
rickettsia
Icterohemorrhagic leptospriosis - sever form with jaundice and azotemia from liver and kidney dysfxn - ; fever hemorrhage and anemia

14. currant jelly sputum
Toxplasmosis
Klebsiella
ribosomes (eukaryotic) - size
ADP- R AB toxin - inactivates EF-2; causes pharyngitis and pseudomembrane in the throat (similar to pseudomonas exotoxin A)

15. Same organism must be found in all cases of disease

Warning: Invalid argument supplied for foreach() in /var/www/html/basicversity.com/show_quiz.php on line 183

16. Cat scratch disease - can cause bacillary angiomatosis in immuncoCised patients - can be confused with KS
capsid - definition
giardia
Heat labile toxin
Bartonella sp

17. Intestinal flora that causes lobar pneumonia in alcoholics and diabetics when aspirated
Klebsiella
endospores - definition
Echinococcus granulosus
HPV 6 and 11 - condylomata acuminata

18. This infxn is usually asymptomatic in mom or has vesicular lesions and causes temporal encephalitis - and vesicular lesions in the neonate - org and transmission
Palivizumab
HSV - skin or mucous membrance contact
Nystatin for superficial - ampho B for systemic
Papilloma - polyoma (circular - supercoiled) and hepadna (circular incomplete)

19. Are atypical lymphocytes actually atypical?
No they are T cells reacting to EBV infected cells
Capsid protein
mycoplasma (5) - description
Edema factor - part of the toxin complex - is an adenylate cyclase

20. Tail fibers attach to outside of host cell
adsorption (B)
Bacterial superinfection
Herpesviruses - HBV - smallpox
Plasmodium

21. What is Treponema - tricky Ts
3 groups in archaea
S. aureus
Spirochete - causes syphillis - or yaws (T. pertenue)
penetration (AV)

22. What OI/disease occurs in the mouth and throat of AIDS pts
Fever - malaise leading to agitation - photophobia - hydrophobia leading to paralysis - coma and death
Brucella sp
Thursh - HSV - CMV - oral hairy leukoplakia from EBV
nucleus

23. Lobe- like projections of the cytoplasm Amoeba
Guillain barre
Ring enhancing brain lesions
pseudopodia
Bullet shaped capsid - long incubation period before sx onset

24. What are the 4 phases of HIV
Rubella german measles
Wound and burn infectinos - Pneumonia in CF - sepsis - external otitis (swimmer's ear) - UTI - drug use and diabetic osteomyelitis and hot tub follculitis
Treponema - 2ndary syphillis
Flulike (acute) - feeling fine (latent) - falling count - final crisis

25. What is the treatment for tinea versicolor
Topocal miconazole - selenium sulfide
Cytoplasm - except influenza and retroviruses
Transfer of just plasmid in F+ and transfer of plasmid plus some flanking genes in Hfr x F-
Surfers in the tropics

26. What happens in stage 2 of lyme disease

Warning: Invalid argument supplied for foreach() in /var/www/html/basicversity.com/show_quiz.php on line 183

27. Spherical
coccus
microaerophilic
A second - different antigenic determinant of the HBV core - HBeAg indicates active viral replication and therefor high transmissability
No they are T cells reacting to EBV infected cells

28. What toxin mediated diseases does staph aureas cause
Toxic shock syndrome (TSST-1) - scalded skin syndrome (exfoliative toxin) - rapid onste fod poisoning (enterotoxin
Enterobius verniculum (pinworm - nematode) - food contaminated with eggs - bendazoles or pyrantel pamoate
Oral thrush - tinea pedis - reactivation VZV - reactivation TB - bacterial infxns (H flu - S pneumo - Salmonella)
E. coli

29. What are neoplasms associated with HIV

Warning: Invalid argument supplied for foreach() in /var/www/html/basicversity.com/show_quiz.php on line 183

30. Which bacteria is an important cause of subacute endocarditis and bacteremia in colon cancer patients
Trigeminal and dorsal root ganglia
Strep bovis - also group D
rickettsia
Inc - inc lymphos - inc - dec

31. What species causes bloody diarrhea is a protozoan
Allergic bronchopulmonary aspergillosis - lung cavity aspergilloma 'fungus ball' invasice aspergillosis in immunoCised pts and those with chronic granulomatous disease
Entamoeba histolytica
Fever - rash - shock - S aureas - TSST-1
Cough - coryza - conjunctivitis

32. Is pneumocystis a fungus or a protazoan
Caused by bacteria Rickettsia prowazekki - rickettsia typhi - rickettsia tsutsugamushi
Yeast - protazoan
trichomoniasis...
Smallpox - although eradicated - could be used in germ warfare Vaccinia - cowpox 'milkmaid's blisters' Molluscum contagiosum - flesh colored dome lesions with central dimple

33. biliary tract disease - cholangiocarcinoma - parasite
basic shapes of bacteria
Clonorchis sinensis
endospores - definition
Enterobius verniculum (pinworm - nematode) - food contaminated with eggs - bendazoles or pyrantel pamoate

34. What are the only double stranded RNA viruses
Gives rigid support - protects against osmotic pressure - sugar backbone with cross linked peptide side chains
Antigen in vaccines
Wuchereria bancrofti - femile mosquito - 9 months to 1 year after bite to develop symptoms - diethylcarbmazine
Reoviridae - rotavirus

35. Binary fission + cytokinesis
EBV
replication for prokaryotes
Reverse transcriptase - HIV - HTLV - T cell leukemia
Bad xray - worse than pt - high titer of cold agglutinins (IgM) which can agglutinate or lyse RBCs - grown on Eaton's agar

36. Non - hodgkin lymphoma large cell type often in oropharynx (waldeyer's ring) of HIV pos pt
Treponema - primary syphillis
infection process of animal viruses (6)
EBV
CMV retinitis

37. unimmunized child with meningitis - microbe colonized the nasopharynx can lead to myalgia and paralysis
Subcutenous plaques - polyarthritis - erythema marginatum - chorea - carditis - no 'rheum' for SPECCulation
H. flu type B - meningococcal vaccines
hypertonic solution
H flu type B

38. What does parainfluenza cause
Enterococci (E. faecalis - E. faecium) nl colonic flora - pen G resistant - cause UTI and subacute endocarditis
Croup - seal like barking cough
lysis
S. aureus

39. asplenic pt
Encapsulated microbes SHiN
Attachment to host T cell
Provides resistance to dehydration - heat and chemicals; keratin like coat; dipicolinic acid
CMV retinitis and esophagitis - disseminated M avium intracellulare - cryptococcal meningoencephalitis

40. Which two bacteria are gram pos rods forming long braching filaments resembling fungi
Dysentery from shiga like toxin - O157:H7 is common serotype - produces HUS
Actinomyces and nocardia
CAMP factor enlarges area of hemolysis formed by S. aureus
Nl/inc - inc lymphos - nl - inc - nl

41. HaemoPhilus causes....
Papilloma - polyoma - hepadnavirus
Epiglottitis (cherry- red in kids) meningitis - otitis media and pneumonia
R. prowazekii
Herpes genitalis - neonatal herpes - sexual contact - perinatal

42. Locomotion or can move substances along the cell
HIV - sexual
cilia - function
Dysuria - frequency - urgency - suprapubic pain - WBCs but not casts in urine
Food - fingers - feces - flies

43. What kind of immunity to live attenuated viral vaccines induce and What is the concern
A second - different antigenic determinant of the HBV core - HBeAg indicates active viral replication and therefor high transmissability
Humoral and cell mediate - can revert to virulence
Shiga like toxin - botulinum toxin - cholera toxin - diptheria toxin - erythrogenic toxin of s. pyogenes
Actinomyces isreallii

44. Contains ribosomes and is associated with protein synthesis
LCMV - lymphocytic choriomeningitis virus - Lassa fever encephalitis - spread by mice
Avain resevoir
Endotoxin/LPS - the periplasmic space (location of many beta lactamases)
rough ER

45. What are the black skin lesions in anthrax caused by
German measles - fever - posauricular tenderness - lymphadenopathy - arthralgias - fine truncal rash - mild disease in children but serious congenital disease (a TORCH infxn)
Travels retrograde fashion up nerve axons
Rabies - influenza - salk polio - HAV
Black necrosis surrounded by edematous ring - caused by letha factor and edema factor

46. How are mucor and rhizopus diagnosed in the lab
Mold with irregular nonseptate hyphae branching at wide angles
Mediate adherence of bacteria to cell surface;sex pilus forms attachment between 2 bacteria during conjugation - glycoprotein
bacteriophage - definition
IVDU

47. Tissue died
gas gangrene
Muramic acid
Influenza virus
Pneumoniae and psittaci

48. Cell walls contain mycolic acid
Mononuclear cells
3 groups in archaea
acid- fast organism - definition
mycology

49. Long rods that can be rigid or flexible
helical shape - definition
Tumbling motility - meningitis in newborns - unpasteurized milk
penetration (AV)
Togavirus - german 3 day measles

50. Where can salmonella typhi remain chronically
Legionella
SHiN - strep pneumo - h flu - neisseria
Humoral and cell mediate - can revert to virulence
Gallbladder