Test your basic knowledge |

USMLE Step 1 Immunology

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What amine is the main chemical mediator released by mast cells? Where does it act What does it result in?






2. What is the white pulp of the spleen?






3. Often bacteria are associated with being killed by humoral immunity. Name some bugs that require cell mediated immunity because they evade humoral response






4. what secretes IL 4?






5. What are the two signals required for B cell class switching? Which is the second signal?






6. Describe the complement independent Type II hypersenstivity reaction. Give an example.






7. What is colostrum?






8. Which antibody mediates immunity to worms? how?






9. what ensure that a memory response is generated?






10. What are the autoantibodies for scleroderma (CREST)? scleroderma diffuse?






11. What happens when a T helper cell in the paracortical section encounters an antigen? a cytotoxic t cell? a B cell in the cortical section?






12. Which disease is associated with DR3?






13. What are the symptoms of serum sickness?






14. Give three examples of bacteria that use antigenic variation and how.






15. What is the main function of IL 8?






16. What happens in a deficiency of C3?






17. What are the autoantibodies for polymyositis and dermatomyositis?






18. What are the autoantibodies for myasthenia gravis?






19. What are the autoantibodies for autoimmune hepatitis?






20. What is the presentation of hyperIgM syndrome?






21. What is chronic mucocutaneous candidiasis d/t?






22. What are the autoantibodies for type I diabetes mellitus?






23. hat is the presentation of Jobs syndrome or Hyper IgE?






24. Which type of selection of thymic development provides central tolerance?






25. what happens in a deficiency of C5- C8? why dont you get recurrent pyogenic infections like in C3 def?






26. What are the autoantibodies for Mixed connective tissue disease?






27. What is the antimetabolite precursor of 6 mercaptopurine? What is the result?






28. What type of cells do NK cells attack? with What tools? by necrosis or apoptosis?






29. What are the main cell surface proteins on B cells?






30. What does granulysin do?






31. What is recomb beta interferon used for?






32. What are the three immune privileged sites? why are they called that? what happens after infection in these areas?






33. Which disease is associated with DR7?






34. The ______ in the BM are DN - the DP are in the cortex of thymus






35. ________ regulate the cell mediated response.






36. What is the pathogenesis of HyperIgE syndrome? What are the labs?






37. What are the autoantibodies for graves?






38. which antibodies prevent antigens from binding mucosal surfaces?






39. What lymph node drains the testes?






40. What are the main symptoms of T cell immunodeficiencies?






41. What is three common causes of severe combined immunodef? What is the result of all three?






42. In thymic development - What is the positive selection? negative selections?






43. what else does interferon gamma do other than inducing ribonuclease production - activating NK cells - inducing increased MHC expression?






44. What cytokines to Th2 secrete?






45. What are the autoantibodies for Celiac disease?






46. What is the arthus reaction? What is the difference between arthus and serum sickness? give an example. How do you test for it?






47. What portion of the lymph node is not well developed in DiGeorge Syndrome?






48. describe the pathogenesis of delayed type IV hypersensitivity






49. How do we use thymus dependent antigens to prevent infection from organisms that lack a peptide component?






50. What is an autograft? syngeneic graft? allograft? xenograft? What is an ex of an allograft? xenograft?







Sorry!:) No result found.

Can you answer 50 questions in 15 minutes?


Let me suggest you:



Major Subjects



Tests & Exams


AP
CLEP
DSST
GRE
SAT
GMAT

Most popular tests