Test your basic knowledge |

USMLE Step 1 Immunology

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Which cytokines do Th2 release and For what?






2. Which diseases are associated with DR4?






3. What are some catalase positive organisms?






4. What are the main Cell surface proteins on T cells?






5. Monomer in circulation - ___ when secreted






6. What are the main symptoms of B cell immunodeficiencies?






7. Which HLA's are included in MHC I? MHC II?

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8. What are the major functions of Antibodies?






9. What is oprelevkin? and What is it used for?






10. What is colostrum?






11. What are C1 - C2 - C3 - C4 important for?






12. What are the T cell functions?






13. Name three things that IL 1 does as a cytokine. other than the liver - who secretes IL 1






14. What are the autoantibodies for hashimotos?






15. How is i Th1 helper cell inhibited?






16. What are the autoantibodies for primary biliary cirrhosis?






17. If the alternative pathway is constitively active - how come normal cells don't get attacked with MAC?






18. Which are the only two antiinflammatory cytokines?






19. What is the defect in hyper IgM syndrome? What are the lab results?






20. Which antibodies can be multimeric?






21. What lymph node drains the testes?






22. what cell surface proteins are on all APCs?






23. other than eat and bite RBCs what else do Macrophages of spleen do>






24. What are the autoantibodies for wegeners granulomatosis?






25. Which disease is associated withB B27?






26. What is the defect in Leukocyte adhesion defect? What is the presentation? What are the labs?






27. What is an example of a parasite showing antigenic variation?






28. What is passive immunity?






29. What are the mediators that mast cells release?






30. Which antibody mediates immunity to worms? how?






31. What is the clinical use for sirolimus? what should you combine it with?






32. Other than stimulating fever - what else does IL 6 do?






33. What portion of the lymph node is not well developed in DiGeorge Syndrome?






34. What is the pathology in hyperacute transplant rejection?






35. What are target cells?






36. What are the autoantibodies for Celiac disease?






37. after C3 spontaneously hydrolyzes to C3b and C3a - what happens to C3a?






38. what results in symptoms of shock in an acute hemolytic transfusion reaction?






39. What is the clinical use for azathioprine?






40. What lymph node drains the breast?






41. What is MHC II made out of? Where is it found? What does it bind to? What type of antigens does it present?






42. What are the autoantibodies for myasthenia gravis?






43. All transplant rejections - _____________ are mediated by Type IV hypersensitivity






44. What is the most common example of passive immunity?






45. What are the main cell surface proteins on B cells?






46. What are the PALS?






47. which antibodies can bind complement?






48. which of the transplant rejections is antibody mediated? why does it occur?






49. What is the symptoms involved in graft versus host disease? it What transplant cases does it usually occur? give an example






50. where are complements produced?