Test your basic knowledge |

USMLE Step 1 Immunology

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What are the cell surface proteins on NK cells?






2. What links the adaptive and innate immunity?






3. What is the thymus ? Where is it located? is it encapsulated? How many lobes does it have?






4. ________ regulate the cell mediated response.






5. What part of the complement system also acts as an opsonin? What is opsonization? can you Name two other opsonins?






6. What are the autoantibodies for pernicious anemia?






7. what cell surface proteins are on all APCs?






8. can igG cross the placenta?






9. Which HLA's are included in MHC I? MHC II?

Warning: Invalid argument supplied for foreach() in /var/www/html/basicversity.com/show_quiz.php on line 183


10. What is the clinical use of Muromonab?






11. What are the autoantibodies for graves?






12. give an example of a virus that uses antigenic variation. What does a major variation result in? minor?






13. What lymph node drains the breast?






14. What are the autoantibodies for autoimmune hepatitis?






15. What are the autoantibodies for systemic sclerosis?






16. In general What are T cells good for?






17. What is the most common selective Ig deficiency? What is the presentation?






18. What is a type I hypersensitivity reaction? What is atopic?






19. What is the main function of interferons?






20. what results in symptoms of shock in an acute hemolytic transfusion reaction?






21. What does interferon gamma do? What two type of cells does it attack mostly?






22. What is muromonab - CD3 (OKT3)






23. What are the main symptoms of T cell immunodeficiencies?






24. What type of cells do NK cells attack? with What tools? by necrosis or apoptosis?






25. What are the two signals required for T cells? what happens after?






26. What kinds of receptors activate innate immunity?






27. The Fc region is found on the...






28. Which disease is associated with B8?






29. How do you test for type III hypersensitivity?






30. How do we use thymus dependent antigens to prevent infection from organisms that lack a peptide component?






31. what ensure that a memory response is generated?






32. How do endotoxin/LPS of gram negative bacteria stimulate the immune system if they do not have a peptide fragment?






33. How does igA cross the epithelium?






34. What part of the lymph node specifically expands during a cellular immune response? when would this occur?






35. What are the three immune privileged sites? why are they called that? what happens after infection in these areas?






36. What cytokines to Th2 secrete?






37. What does interferon gamma do to be antiviral?






38. All transplant rejections - _____________ are mediated by Type IV hypersensitivity






39. What is passive immunity?






40. What is recomb gamma interferon used for?






41. Which disease is associated with HLA A3?






42. What lymph node drains the duodenum - jejunum?






43. What is an autograft? syngeneic graft? allograft? xenograft? What is an ex of an allograft? xenograft?






44. are Th cells involved in trapping of antigens of endotoxin/LPS?






45. give an example of how influenza does a major antigenic shift.






46. What are the function of B cells?






47. IgE has the ___________ in the serum






48. What is serum sickness? give an example.






49. What are the T cell functions?






50. T/F B cells do not require a second signal