Test your basic knowledge |

USMLE Step 1 Immunology

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What is the end result of complement activation? what bugs are this important for? through what pathway and why?






2. What is the pathogenesis of chronic granulomatous disease; What is the presentation? What is the labs?






3. What is the mode of inheritance of Chediak Higashi syndrome? What is the disease d/t? What does it result in? What is the presentation?






4. can igG cross the placenta?






5. What are the sinusoids of the spleen? What is the difference between a spleen and a lymph node?






6. What is anergy? why does this occur?






7. What is serum sickness? give an example.






8. What does interferon gamma do? What two type of cells does it attack mostly?






9. What is the autoantibody for SLE that is nonspecific? Specific?






10. What is chronic mucocutaneous candidiasis d/t?






11. Which HLA's are included in MHC I? MHC II?

Warning: Invalid argument supplied for foreach() in /var/www/html/basicversity.com/show_quiz.php on line 183


12. What portion of the lymph node is not well developed in DiGeorge Syndrome?






13. What is the receptor for EBV? On what cells is that located?






14. what else does interferon gamma do other than inducing ribonuclease production - activating NK cells - inducing increased MHC expression?






15. What can cause a lymph node enlargement?






16. Which diseases are associated with DR4?






17. What are the autoantibodies for primary biliary cirrhosis?






18. What are the cell surface proteins on NK cells?






19. What cytokines are released by Th1 cells?






20. where do NK cells develop?






21. What are the autoantibodies for drug induced lupus?






22. What are the autoantibodies for graves?






23. What is the pathology in hyperacute transplant rejection?






24. what happens in order for class switching to occur (after being activated by IL and cd40 L)?






25. What is the pathogenesis of acute transplant rejection? When does it occur?






26. after C3 spontaneously hydrolyzes to C3b and C3a - what happens to C3a?






27. Which disease is associated with B8?






28. Which is the main antibody that provides passive immunity to infants?






29. What lymph node drains the sigmoid colon?






30. What does Interferon alpha and beta do? how?






31. What are the mediators that mast cells release?






32. IgE has the ___________ in the serum






33. Type Iv hypersensitivity is...






34. Name two endogenous pyrogens






35. What is the defect in Leukocyte adhesion defect? What is the presentation? What are the labs?






36. Name three things that IL 1 does as a cytokine. other than the liver - who secretes IL 1






37. What are HEV? Where are they found? Where does the vasculature of the lymph node travel to?






38. What is the clinical use for sirolimus? what should you combine it with?






39. What kinds of receptors activate innate immunity?






40. What is the general structure of an Ab?






41. What are MHC's necessary for? By themselves?






42. Give three examples of bacteria that use antigenic variation and how.






43. which antibodies can bind complement?






44. Which cytokines do Th2 release and For what?






45. Name the three opsonins






46. What are superantigens? give two examples.






47. What is the difference of IgE AIHA and IgG AIHA if they are both complement dependent type II hypersensitivities?






48. What does granulysin do?






49. What is the white pulp of the spleen?






50. What do multimeric antibodies require for assembly?







Sorry!:) No result found.

Can you answer 50 questions in 15 minutes?


Let me suggest you:



Major Subjects



Tests & Exams


AP
CLEP
DSST
GRE
SAT
GMAT

Most popular tests