Test your basic knowledge |

USMLE Step 1 Immunology

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. In order to produce Antibodies - does the antigen have to be phagocytosed? give an example with a bug and an autoimmune (type II hypersensitivity for example).






2. Which helper T cells' development is induced by IL 4? IL 12?






3. What lymph node drains the sigmoid colon?






4. A lymph node is a ________ lymphoid organ.






5. What is a type I hypersensitivity reaction? What is atopic?






6. can igG cross the placenta?






7. Which disease is associated with DR3?






8. What is the defect in Leukocyte adhesion defect? What is the presentation? What are the labs?






9. explain the process from beginning (ie phagocytosis of the peptide) to end of how Abs are formed in Goodpasteurs.






10. What are target cells?






11. What is colostrum?






12. What lymph node drains the stomach?






13. Which diseases are associated with DR4?






14. What are superantigens? give two examples.






15. What is the autoantibody for SLE that is nonspecific? Specific?






16. which antibody activate mast cells - basophils - and eosinophils?






17. What is the general structure of an Ab?






18. To what portion of the Antibody do the complements bind?






19. So antibodies are the effectors for the humoral response. List some of their functions.






20. What is the pathogenesis of a candida skin test?






21. What is the pathology in hyperacute transplant rejection?






22. How do we use thymus dependent antigens to prevent infection from organisms that lack a peptide component?






23. What is immune complex disease? give an example.






24. which type of immunity is slow but long lasting? as opposed to...






25. is IgM an opsonizer?






26. How is the antigen loaded onto a MHC II?






27. What is the mode of inheritance of Chediak Higashi syndrome? What is the disease d/t? What does it result in? What is the presentation?






28. ________ regulate the cell mediated response.






29. What are the function of B cells?






30. What amine is the main chemical mediator released by mast cells? Where does it act What does it result in?






31. What is the arthus reaction? What is the difference between arthus and serum sickness? give an example. How do you test for it?






32. hat is the presentation of Jobs syndrome or Hyper IgE?






33. What are the main symptoms of T cell immunodeficiencies?






34. what prevents NK cells from killing normal cells if their default is to kill?






35. What is the antimetabolite precursor of 6 mercaptopurine? What is the result?






36. Leukocyte adhesion defect presents with...






37. Which diseases are associated with DR5?






38. what cell surface proteins are on all APCs?






39. What do mature naive B lymphocytes express?






40. Describe the capsular structure of a lymph node; What are the functions of the LN?






41. when can graft versus host disease? What is the result?






42. To what disease do the autoantibodies to IgG (rheumatoid factor)?






43. How fast does it occur?






44. What are some sinopulmonary infections?






45. What is the thymus ? Where is it located? is it encapsulated? How many lobes does it have?






46. __________ are a part of the innate system.






47. after C3 spontaneously hydrolyzes to C3b and C3a - what happens to C3a?






48. Which disease is associated with B8?






49. What cytokines are released by Th1 cells?






50. What is the defect in Brutons agammaglobulinemia? What is its effect on B cells? What is its inheritance pattern?






Can you answer 50 questions in 15 minutes?



Let me suggest you:



Major Subjects



Tests & Exams


AP
CLEP
DSST
GRE
SAT
GMAT

Most popular tests