Test your basic knowledge |

USMLE Step 1 Immunology

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What does IL 5 do?






2. What is the monoclonal antibody to IL2 on activated T cells? What is it used for?






3. What links the adaptive and innate immunity?






4. What is muromonab - CD3 (OKT3)






5. What part of the complement system also acts as an opsonin? What is opsonization? can you Name two other opsonins?






6. What are the autoantibodies for Mixed connective tissue disease?






7. Which is the main antibody that provides passive immunity to infants?






8. What is recomb alpha interferon used for?






9. The secondary follicles have __________; primary follicles are dense






10. What is the pathology in hyperacute transplant rejection?






11. can igG cross the placenta?






12. Which Thelper cell activated Macrophages? by secreting what? what else does Th1 secrete? For what?






13. The pathogenesis of contact dermatitis is ________ hypersensitivity






14. What is the main function of IL 8?






15. What is a factor that is a predictor for a bad transplantation?






16. What is the symptoms involved in graft versus host disease? it What transplant cases does it usually occur? give an example






17. What lymph node drains the thigh?






18. Which is the most abundant antibody in blood?






19. What does IL 4 do?






20. What is serum sickness? give an example.






21. What is the clinical use for sirolimus? what should you combine it with?






22. What is hereditary angioedema? What are the C3 levels?






23. What are the cell surface proteins for Macrophages? which two are for opsonins?






24. What kinds of receptors activate innate immunity?






25. What is Aldesleukin? What is it used for






26. What is the presentation of common variable immunodef? and What are the labs?






27. Which is the main antibody in the delayed or secondary response to an antigen?






28. What is the pathogenesis of acute transplant rejection? When does it occur?






29. What is the marginal zone of the spleen? what happens there?






30. What is the arthus reaction? What is the difference between arthus and serum sickness? give an example. How do you test for it?






31. which B and T cell disorder presents with specifically low IgM?






32. What portion of the lymph node is not well developed in DiGeorge Syndrome?






33. What cytokines to Th2 secrete?






34. Describe complement dependent Type II hypersensitivity. Give an example.






35. Which disease is associated with DR3?






36. What are the function of B cells?






37. What is filgrastim and sargramostim? and What is it used for?






38. what happens in order for class switching to occur (after being activated by IL and cd40 L)?






39. What does interferon gamma do to be antiviral?






40. What are the autoantibodies for graves?






41. Which helper T cells' development is induced by IL 4? IL 12?






42. If the alternative pathway is constitively active - how come normal cells don't get attacked with MAC?






43. what characterizes an arthus reaction?






44. Only the _______ contribute to the Fc region






45. The alternative pathway is the only constutively...






46. What is oprelevkin? and What is it used for?






47. What are the two signals to kill for NK cells?






48. What does it mean if there are igM in the serum at birth?






49. Describe the Mannose Lectin pathway






50. is IgM an opsonizer?