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USMLE Step 1 Immunology

Instructions:
  • Answer 50 questions in 15 minutes.
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  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What lymph node drains the sigmoid colon?






2. What is the late phase reaction of anaphylaxis allergy? what mediates it?






3. What is serum sickness? give an example.






4. What lymph node drains the upper limb?






5. what will NK cells do to cells covered in IgG Ab? why?






6. Describe the capsular structure of a lymph node; What are the functions of the LN?






7. What is muromonab - CD3 (OKT3)






8. What are MHC's necessary for? By themselves?






9. describe the classic complement pathway.






10. What does IL 4 do?






11. Give three examples of bacteria that use antigenic variation and how.






12. What is the pathology seen in chronic transplant rejection?






13. What are the autoantibodies for graves?






14. What is the main cytokine that activates eosinophils?






15. What are complements in the complement system? What activates them? there seems to be different ones - What are these pathways called?






16. What two ways do you test for a type 1 hypersensitivity reaction? what will you see?






17. What is the pathology in hyperacute transplant rejection?






18. in which immunodef order do you see a lot of pus? no pus?






19. What lymph node drains the thigh?






20. What is the arthus reaction? What is the difference between arthus and serum sickness? give an example. How do you test for it?






21. give an example of how influenza does a major antigenic shift.






22. What is the presentation of hyperIgM syndrome?






23. What is chronic mucocutaneous candidiasis d/t?






24. Which cytokines do Th2 release and For what?






25. What is wiskott aldrich syndrome? What is its mode of inheritance? What is the pathogenesis of disease? What is its triad of presentation? what labs does it present with?






26. What is recomb beta interferon used for?






27. How is i Th1 helper cell inhibited?






28. What are the autoantibodies for myasthenia gravis?






29. What type of cells do NK cells attack? with What tools? by necrosis or apoptosis?






30. other than eat and bite RBCs what else do Macrophages of spleen do>






31. What is hereditary angioedema? What are the C3 levels?






32. What is the symptoms involved in graft versus host disease? it What transplant cases does it usually occur? give an example






33. What are the three types of lymphocytes?






34. What do mature naive B lymphocytes express?






35. What lymph node drains the anal canal (below the pectinate line)?






36. IgM can exist as a _______ also






37. What is the toxicity of muromonab?






38. What are the autoantibodies for systemic sclerosis?






39. What does Interferon alpha and beta do? how?






40. What is a type I hypersensitivity reaction? What is atopic?






41. The idiotype; the Fc portion determines the...






42. what prevents NK cells from killing normal cells if their default is to kill?






43. What is MHC I made out of? Where is it found? What does it bind to? What type of antigens does it present?






44. which antibodies can bind complement?






45. How does the alternative pathway lead to MAC activation?






46. What is filgrastim and sargramostim? and What is it used for?






47. What is the main cytokine released by T cells? What does it do






48. which B and T cell disorder presents with specifically low IgM?






49. Give an example of someone who could get hyperacute transplant rejection.






50. What does CD16 on NK cells do?







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