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USMLE Step 1 Immunology

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Which cytokines do Th2 release and For what?






2. describe the classic complement pathway.






3. What are the autoantibodies for graves?






4. What is oprelevkin? and What is it used for?






5. What does IL 5 do?






6. What is hereditary angioedema? What are the C3 levels?






7. What is the presentation of common variable immunodef? and What are the labs?






8. What are the labs in brutons agammaglobulinemia?






9. Type Iv hypersensitivity is...






10. which cytokine inhibits TH2 cells? secreted by who?






11. What does CD16 on NK cells do?






12. What is digoxin immune Fab used for?






13. The idiotype; the Fc portion determines the...






14. with failed maturation of B cells in Brutons agammaglobulinemia - What is its effect on immune pathways and why?






15. in which immunodef order do you see a lot of pus? no pus?






16. What is the mechanism for sirolimus? what else it known as?






17. What is the symptoms involved in graft versus host disease? it What transplant cases does it usually occur? give an example






18. What are the main cell surface proteins on B cells?






19. What portion of the lymph node is not well developed in DiGeorge Syndrome?






20. What is Aldesleukin? What is it used for






21. What does granulysin do?






22. What are the autoantibodies for Mixed connective tissue disease?






23. What is the pathogenesis of IgG AIHA ABO hemolytic disease of a newborn? describe what happens.






24. How do we use thymus dependent antigens to prevent infection from organisms that lack a peptide component?






25. Which type of selection of thymic development provides central tolerance?






26. What is the pathogenesis of HyperIgE syndrome? What are the labs?






27. What cytokines are released by Th1 cells?






28. which antibody is involved in the primary response or immediate response to an antigen?






29. What are some catalase positive organisms?






30. which of the transplant rejections is antibody mediated? why does it occur?






31. What is immune complex disease? give an example.






32. What are HEV? Where are they found? Where does the vasculature of the lymph node travel to?






33. What are the T cell functions?






34. Which is the most abundant antibody in blood?






35. Name three things that IL 1 does as a cytokine. other than the liver - who secretes IL 1






36. What lymph node drains the stomach?






37. What is the main function of IL 8?






38. What is the main function of interferons?






39. T/F B cells do not require a second signal






40. other than C3a - what other complement acts as an anaphyloxin?






41. What lymph node drains the lateral side of the dorsum of the foot?






42. What happens in a secondary follicle?






43. How is sirolimus different from tacrolimus?






44. What are the autoantibodies for myasthenia gravis?






45. From where do cytokines come from?






46. What is passive immunity?






47. What is the most common selective Ig deficiency? What is the presentation?






48. What is the pathogenesis of chronic transplant rejection? When does it occur? is it reversible?






49. are Th cells involved in trapping of antigens of endotoxin/LPS?






50. What do mature naive B lymphocytes express?