Test your basic knowledge |

USMLE Step 1 Immunology

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. The secondary follicles have __________; primary follicles are dense






2. What lymph node drains the scrotum?






3. What are the three types of APCs?






4. What lymph node drains the lateral side of the dorsum of the foot?






5. What are MHC Class molecules (ie what macromolecule are they made out of)? what gene are responsible for MHC?






6. What are the autoantibodies for Celiac disease?






7. What are the autoantibodies for hashimotos?






8. other than eat and bite RBCs what else do Macrophages of spleen do>






9. which antibodies can bind complement?






10. What are C1 - C2 - C3 - C4 important for?






11. which of the hypersensitivity reactions is not Ab mediated?






12. In thymic development - What is the positive selection? negative selections?






13. How do we use thymus dependent antigens to prevent infection from organisms that lack a peptide component?






14. What is the result of an IL 12 deficiency? What is the presentation? What are the labs?






15. What is the clinical use of Muromonab?






16. What does IL 4 do?






17. What is the toxicity of azathioprine?






18. What is ataxia telangectasia? What is it caused by? What is the triad of presentation? and its labs?






19. What type of cells do NK cells attack? with What tools? by necrosis or apoptosis?






20. can igG cross the placenta?






21. The Fc region is found on the...






22. What does granulysin do?






23. To what portion of the Antibody do the complements bind?






24. What are the main cell surface proteins on B cells?






25. what happens in order for class switching to occur (after being activated by IL and cd40 L)?






26. A lymph node is a ________ lymphoid organ.






27. What are howell jolly bodies?






28. What type of side chains are found on Fc region of an antibody?






29. What is a factor that is a predictor for a bad transplantation?






30. Which cytokines do Th2 release and For what?






31. IgE has the ___________ in the serum






32. What are the three types of lymphocytes?






33. What are HEV? Where are they found? Where does the vasculature of the lymph node travel to?






34. What is serum sickness? give an example.






35. How does igA cross the epithelium?






36. What is Aldesleukin? What is it used for






37. What are the labs in brutons agammaglobulinemia?






38. what else does interferon gamma do other than inducing ribonuclease production - activating NK cells - inducing increased MHC expression?






39. What are the autoantibodies for myasthenia gravis?






40. What does IL 2 do?






41. Give three examples of bacteria that use antigenic variation and how.






42. which cells have more complete tolerance - B or T cells?






43. What cytokines do macrophages release? who else can secrete IL 6? IL 12?






44. What are the autoantibodies for drug induced lupus?






45. What bugs can actually infect the lymph node itself?






46. What is passive immunity?






47. where are complements produced?






48. What are the autoantibodies for polymyositis and dermatomyositis?






49. How does complement link innate and adaptive?






50. Name the three opsonins