Test your basic knowledge |

USMLE Step 1 Immunology

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What are MHC's necessary for? By themselves?






2. What lymph node drains the duodenum - jejunum?






3. What is thrombopoietin used for?






4. What are the autoantibodies for other vasculitides?






5. ________ regulate the cell mediated response.






6. Which disease is associated with B8?






7. What is the main cytokine that activates eosinophils?






8. What is the presentation of scid? treatment?






9. which of the hypersensitivity reactions is not Ab mediated?






10. What is the end result of complement activation? what bugs are this important for? through what pathway and why?






11. What is the monoclonal antibody to IL2 on activated T cells? What is it used for?






12. which immunodeficiency presents with delayed separation of the umbilicus? ataxia? telangiectasia?albinism? anaphylaxis on exposure to blood products with IgA? tetany?retained primary teeth? peripheral neuropathy?






13. The Fc region is found on the...






14. What lymph node drains the lateral side of the dorsum of the foot?






15. What are the major functions of Antibodies?






16. What is immune complex disease? give an example.






17. What is the pathogenesis of acute transplant rejection? When does it occur?






18. What are some sinopulmonary infections?






19. What lymph node drains the breast?






20. What are some catalase positive organisms?






21. How is the antigen loaded onto a MHC II?






22. which of the transplant rejections is antibody mediated? why does it occur?






23. What is muromonab - CD3 (OKT3)






24. What is three common causes of severe combined immunodef? What is the result of all three?






25. which type of immunity is slow but long lasting? as opposed to...






26. What are the autoantibodies for sjorgens syndrome?






27. What does interferon gamma do to be antiviral?






28. What is anergy? why does this occur?






29. What are the function of B cells?






30. Which is the main antibody that provides passive immunity to infants?






31. What do mature naive B lymphocytes express?






32. Describe the capsular structure of a lymph node; What are the functions of the LN?






33. What are the autoantibodies for wegeners granulomatosis?






34. What are the main symptoms of B cell immunodeficiencies?






35. What is Aldesleukin? What is it used for






36. IgG...






37. What is chronic mucocutaneous candidiasis d/t?






38. Which cytokines do Th2 release and For what?






39. What is the pathogenesis of chronic transplant rejection? When does it occur? is it reversible?






40. What is the pathogenesis of chronic granulomatous disease; What is the presentation? What is the labs?






41. Name the three opsonins






42. What is the result of an IL 12 deficiency? What is the presentation? What are the labs?






43. Which diseases are associated with DR2?






44. What is hereditary angioedema? What are the C3 levels?






45. What are the autoantibodies for primary biliary cirrhosis?






46. What are the autoantibodies for pernicious anemia?






47. The pathogenesis of contact dermatitis is ________ hypersensitivity






48. What is oprelevkin? and What is it used for?






49. T/F B cells do not require a second signal






50. what cell surface marker is used for NK cells as it is unique to them?