Test your basic knowledge |

USMLE Step 1 Immunology

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What are the cell surface proteins for Macrophages? which two are for opsonins?






2. DTH (delayed type hypersensitivity) is the ________ of a PPD reaction






3. What lymph node drains the rectum (above the pectinate line)?






4. what cytokine does basophils secrete?






5. Which Thelper cell activated Macrophages? by secreting what? what else does Th1 secrete? For what?






6. What are the four steps in phagocytosis? What are the four disease that correspond to each step?






7. describe the pathogenesis of delayed type IV hypersensitivity






8. What are the autoantibodies for myasthenia gravis?






9. What is the pathogenesis of IgG AIHA ABO hemolytic disease of a newborn? describe what happens.






10. What are howell jolly bodies?






11. What are the autoantibodies for sjorgens syndrome?






12. Which diseases are associated with DR4?






13. What lymph node drains the thigh?






14. other than C3a - what other complement acts as an anaphyloxin?






15. What are the autoantibodies for type I diabetes mellitus?






16. Describe the complement independent Type II hypersenstivity reaction. Give an example.






17. How is the thymus organized? what happens in each section?






18. Often bacteria are associated with being killed by humoral immunity. Name some bugs that require cell mediated immunity because they evade humoral response






19. What type of fenestrations are found in the red pulp of the spleen?






20. What is the result of an IL 12 deficiency? What is the presentation? What are the labs?






21. What does IL 4 do?






22. Which disease is associated with B8?






23. Which disease is associated withB B27?






24. What lymph node drains the anal canal (below the pectinate line)?






25. What do macrophages secrete that activate Th1 cells to secrete interferon gamma?






26. What is immune complex disease? give an example.






27. What is an example of a parasite showing antigenic variation?






28. what happens in a deficiency of C5- C8? why dont you get recurrent pyogenic infections like in C3 def?






29. which of the transplant rejections is antibody mediated? why does it occur?






30. Which diseases are associated with DR2?






31. What are the major functions of Antibodies?






32. What is recomb gamma interferon used for?






33. What is the most common example of passive immunity?






34. What are the symptoms of serum sickness?






35. The alternative pathway is the only constutively...






36. What are some sinopulmonary infections?






37. What are the function of B cells?






38. What are the two signals required for Th1 cells? what happens after then activated?






39. what cell surface marker is used for NK cells as it is unique to them?






40. which of the hypersensitivity reactions is not Ab mediated?






41. what happens in a deficiency of C1 esterase inhibitor? DAF?






42. with failed maturation of B cells in Brutons agammaglobulinemia - What is its effect on immune pathways and why?






43. What is thrombopoietin used for?






44. What are the autoantibodies for polymyositis and dermatomyositis?






45. What is the monoclonal antibody to IL2 on activated T cells? What is it used for?






46. What is the common variable immunodeficiency ? How is it different from Brutons?






47. What is the toxicity of muromonab?






48. What is the presentation of hyperIgM syndrome?






49. In thymic development - What is the positive selection? negative selections?






50. Complements are...







Sorry!:) No result found.

Can you answer 50 questions in 15 minutes?


Let me suggest you:



Major Subjects



Tests & Exams


AP
CLEP
DSST
GRE
SAT
GMAT

Most popular tests