Test your basic knowledge |

USMLE Step 1 Immunology

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What are complements in the complement system? What activates them? there seems to be different ones - What are these pathways called?






2. Describe the interstitial tissue of a spleen including the sinuses. What type of cells are found in the four structures (cortex - paracortex - medulla and sinuses)?






3. What are the three types of lymphocytes?






4. are Th cells involved in trapping of antigens of endotoxin/LPS?






5. Which disease is associated withB B27?






6. What are the autoantibodies for wegeners granulomatosis?






7. Which is the main antibody in the delayed or secondary response to an antigen?






8. What lymph node drains the breast?






9. Describe the capsular structure of a lymph node; What are the functions of the LN?






10. which cytokine inhibits TH2 cells? secreted by who?






11. What is the pathogenesis of a candida skin test?






12. What bugs can actually infect the lymph node itself?






13. Describe complement dependent Type II hypersensitivity. Give an example.






14. Which TCR MHC system is important for viral immunity? neoplastic? donor graft cells?






15. IgG...






16. What are the autoantibodies for hashimotos?






17. what will NK cells do to cells covered in IgG Ab? why?






18. What does granzyme do? who secretes it?






19. What is thrombopoietin used for?






20. What amine is the main chemical mediator released by mast cells? Where does it act What does it result in?






21. What is an example of a parasite showing antigenic variation?






22. How do endotoxin/LPS of gram negative bacteria stimulate the immune system if they do not have a peptide fragment?






23. What do mature naive B lymphocytes express?






24. Often bacteria are associated with being killed by humoral immunity. Name some bugs that require cell mediated immunity because they evade humoral response






25. Which Thelper cell activated Macrophages? by secreting what? what else does Th1 secrete? For what?






26. How is i Th1 helper cell inhibited?






27. What is the main function of IL 12? other than macrophages who else can release IL 12?






28. What happens in a deficiency of C3?






29. what prevents NK cells from killing normal cells if their default is to kill?






30. How is the thymus organized? what happens in each section?






31. What is passive immunity?






32. What are the PALS?






33. How does the alternative pathway lead to MAC activation?






34. What is the defect in hyper IgM syndrome? What are the lab results?






35. What are the autoantibodies for drug induced lupus?






36. What cytokines to Th2 secrete?






37. What is a type I hypersensitivity reaction? What is atopic?






38. What are the autoantibodies for Mixed connective tissue disease?






39. What is the main cytokine that activates eosinophils?






40. What lymph node drains the stomach?






41. What are the mediators that mast cells release?






42. For which toxins are preformed antibodies (passive) given?






43. What type of fenestrations are found in the red pulp of the spleen?






44. How do you test for type III hypersensitivity?






45. Which HLA's are included in MHC I? MHC II?

Warning: Invalid argument supplied for foreach() in /var/www/html/basicversity.com/show_quiz.php on line 183


46. which of the hypersensitivity reactions is not Ab mediated?






47. What are some sinopulmonary infections?






48. How do we use thymus dependent antigens to prevent infection from organisms that lack a peptide component?






49. What is the pathogenesis of acute transplant rejection? When does it occur?






50. If an antigen lacks a peptide component How does the adaptive immunity attack it? What type of response is this called. give an example of bugs that do this. what implications does this have on splenectomy?







Sorry!:) No result found.

Can you answer 50 questions in 15 minutes?


Let me suggest you:



Major Subjects



Tests & Exams


AP
CLEP
DSST
GRE
SAT
GMAT

Most popular tests