Test your basic knowledge |

USMLE Step 1 Immunology

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What is the main function of TNF alpha? How does it do this?






2. which antibodies can bind complement?






3. What are the autoantibodies for goodpastures syndrome?






4. What is the most common selective Ig deficiency? What is the presentation?






5. What lymph node drains the lateral side of the dorsum of the foot?






6. The idiotype; the Fc portion determines the...






7. What is passive immunity?






8. What are the four steps in phagocytosis? What are the four disease that correspond to each step?






9. hat is the presentation of Jobs syndrome or Hyper IgE?






10. What is the presentation of scid? treatment?






11. what happens in a deficiency of C1 esterase inhibitor? DAF?






12. IgG...






13. What are the autoantibodies for drug induced lupus?






14. What is the thymus ? Where is it located? is it encapsulated? How many lobes does it have?






15. What is the clinical use of Muromonab?






16. A lymph node is a ________ lymphoid organ.






17. What is the monoclonal antibody to IL2 on activated T cells? What is it used for?






18. What lymph node drains the upper limb?






19. What are the major functions of Antibodies?






20. What is the symptoms involved in graft versus host disease? it What transplant cases does it usually occur? give an example






21. with failed maturation of B cells in Brutons agammaglobulinemia - What is its effect on immune pathways and why?






22. What are some sinopulmonary infections?






23. Which are the only two antiinflammatory cytokines?






24. What lymph node drains the rectum (above the pectinate line)?






25. what secretes IL 4?






26. What are the three types of APCs?






27. Give an example of someone who could get hyperacute transplant rejection.






28. Only the _______ contribute to the Fc region






29. DTH (delayed type hypersensitivity) is the ________ of a PPD reaction






30. What cytokines do macrophages release? who else can secrete IL 6? IL 12?






31. What kinds of receptors activate innate immunity?






32. Which disease is associated with B8?






33. What cytokines to Th2 secrete?






34. what else does interferon gamma do other than inducing ribonuclease production - activating NK cells - inducing increased MHC expression?






35. Which is the most abundant antibody in blood?






36. after C3 spontaneously hydrolyzes to C3b and C3a - what happens to C3a?






37. What are target cells?






38. How is sirolimus different from tacrolimus?






39. What is serum sickness? give an example.






40. Complements are...






41. What is the defect in Leukocyte adhesion defect? What is the presentation? What are the labs?






42. Name the three opsonins






43. All transplant rejections - _____________ are mediated by Type IV hypersensitivity






44. What is colostrum?






45. What does Interferon alpha and beta do? how?






46. where do NK cells develop?






47. describe the classic complement pathway.






48. when can graft versus host disease? What is the result?






49. Name three things that IL 1 does as a cytokine. other than the liver - who secretes IL 1






50. What does CD16 on NK cells do?