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USMLE Step 1 Pharmacology

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. List the specific antidote for this toxin: Heparin






2. What is the effect of the Glitazones in diabetes treatment?






3. Adverse effects of Nifedipine - verapamil?






4. Why would you use pralidoxime after exposure to an organophosphate?






5. For Warfarin What is the Onset of action






6. Which drug(s) cause this reaction: Tubulointerstitial Nephritis (5)?






7. Which drug(s) cause this reaction: Hepatitis?






8. Antimicrobial prophylaxis for Meningococcal infection






9. Antiarrhythmic class IB- effects?






10. Name two organisms Vancomycin is commonly used for?






11. What are the indications for using amphetamine?

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12. What drug is given for Pneumocystis carinii prophylaxis?






13. What is treated with Chloroquine - Quinine - Mefloquine?






14. Hydrochlorothiazide - mechanism?






15. K+ sparing diuretics - toxicity?






16. A common side effects of Interferon (INF) treatment is?






17. Toxic side effects of the Azoles?






18. What enzymes are inhibited by NSAIDs - acetaminophen and COX II inhibitors?






19. What is the category and mechanism of action of Zileuton in Asthma treatment?






20. Acetazolamide - mechanism?






21. What are common toxicities associated with Tetracyclines?

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22. What is the clinical use for Nystatin?






23. Explain pH dependent urinary drug elimination?






24. List five common glucocorticoids.






25. What is the effect of epinephrine infusion on bp and pulse pressure?






26. What is the mechanism of action of the Sulfonylureas?






27. What sympathomimetic would you not prescribe for hypotension in a pt with renal artery sclerosis.






28. MOA: Block mRNA synthesis






29. What is the category of drug names ending in - tropin (e.g. Somatotropin)






30. What antimuscarinic agent is used in asthma and COPD?






31. What is the mechanism of action and clinical use of the antiandrogen Flutamide?






32. How do Sulfonamides act on bacteria?






33. What is used to reverse the action of Heparin?






34. Which diuretics cause acidosis?






35. Hydralazine - clinical use?






36. What is the category of drug names ending in - caine (e.g. Lidocaine)






37. Which RT inhibitors cause Lactic Acidosis?






38. Antiarrhythmic class IV- effects?






39. Clinical use of Isoniazid (INH)?






40. How is Acyclovir used clinically?






41. Why are Methicillin - Nafcillin - and Dicloxacillin penicillinase resistant?






42. Ca2+ channel blockers - mechanism?






43. What is the category of drug names ending in - barbital (e.g. Phenobarbital)






44. Which receptors does phenylephrine act upon?






45. What is the category of drug names ending in - cillin (e.g. Methicillin)






46. Which drug(s) cause this reaction: Osteoporosis (2)?






47. How is Griseofulvin used clinically?






48. What is the category of drug names ending in - zosin (e.g. Prazosin)






49. What are Amantadine - associated side effects?






50. Bretyllium - toxicity?