Test your basic knowledge |

USMLE Step 1 Pharmacology

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What is the category of drug names ending in - tropin (e.g. Somatotropin)






2. What is the effect of guanethidine on adrenergic NE release?






3. What is used to reverse the action of Heparin?






4. What is the MOA for Amphotericin B?






5. List the specific antidote for this toxin: Carbon monoxide






6. What is the mechanism of action of Omeprazole - Lansoprazole?






7. What microorganisms are clinical indications for Tetracycline therapy?

Warning: Invalid argument supplied for foreach() in /var/www/html/basicversity.com/show_quiz.php on line 183


8. What is the category of drug names ending in - triptyline (e.g. Amitriptyline)






9. IV Penicillin






10. What is the memory key for Metronidazole's clinical uses?






11. MOA: Block peptidoglycan synthesis






12. Antiarrhythmic class IV- primary site of action?






13. Which cancer drugs work at the level of mRNA(2)?






14. Name three calcium channel blockers?






15. List the mechanism - clinical use - & toxicity of Cyclophosphamide.






16. Which diuretics cause acidosis?






17. Which antimicrobials inhibit protein synthesis at the 50S subunit? (4)






18. How is Amantadine used clinically?

Warning: Invalid argument supplied for foreach() in /var/www/html/basicversity.com/show_quiz.php on line 183


19. What neurotransmitter does Amantadine affect? How does it influence this NT?






20. What are the clinical uses for Aztreonam?






21. Are penicillinase resistant






22. Name the common Nucleoside Reverse Transcriptase Inhibitors






23. How are the Latent Hypnozoite (Liver) forms of Malaria (P. vivax - P.ovale) treated?






24. How are the HIV drugs used clinically?

Warning: Invalid argument supplied for foreach() in /var/www/html/basicversity.com/show_quiz.php on line 183


25. Does Heparin have a long - medium - or short half life?






26. MOA: Disrupt fungal cell membranes






27. Thiazides - site of action?






28. Which individuals are predisposed to Sulfonamide - induced hemolysis?






29. Amprotericin B ___________ the BBB






30. For Warfarin What is the Mechanism of action






31. Name four Antiarrhythmic drugs in class IA.






32. MOA for Penicillin (3 answers)?






33. What is the most common cause of Pt noncompliance with Macrolides?






34. What is the effect of TCA's on the adrenergic nerve?






35. What enzyme is responsible for the breakdown of ACh in the synaptic cleft?






36. Acetazolamide - clinical uses?






37. Adverse effects of Reserpine?






38. Which drug(s) cause this reaction: Cutaneous flushing (4)?






39. Mannitol - site of action?






40. Mannitol - toxicity?






41. What are the side effects of Rifampin?






42. What are two Glitazones?






43. How can Vancomycin - induced 'Red Man Syndrome' be prevented?






44. How is Ribavirin used clinically?






45. What is an acronym to remember Anti - TB drugs?






46. What are two processes Corticosteroids inhibit leading to decreased inflammation?






47. What enzymes are inhibited by NSAIDs - acetaminophen and COX II inhibitors?






48. Mannitol - mechanism?






49. How can Isoniazid (INH)- induced neurotoxicity be prevented?






50. For Heparin What is the Onset of action