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USMLE Step 1 Pharmacology

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Adverse effects of Hydrochlorothiazide?






2. Procainamide - toxicity?






3. Antiarrhythmic class IV- effects?






4. Which drug(s) cause this reaction: Stevens - Johnson syn. (3)?






5. List the specific antidote for this toxin: Amphetamine






6. List the specific antidote for this toxin: Benzodiazepines






7. For Heparin What is the Structure






8. What is the mechanism of action of the glucocorticoids?






9. What is the category of drug names ending in - azepam (e.g. Diazepam)






10. Digoxin v. Digitoxin: bioavailability?






11. What is an acronym to remember Anti - TB drugs?






12. Adverse effects of Prazosin?






13. What is the memory aid for subunit distribution of ribosomal inhibitors?

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14. What is the receptor affinity and clinical use of isoproterenol?






15. List the specific antidote for this toxin: Opioids






16. Which RT inhibitors cause Lactic Acidosis?






17. Which drug(s) cause this reaction: Focal to massive hepatic necrosis (4)?






18. What are the clinical uses for Ticlopidine - Clopidogrel?






19. What is the mechanism of Azathioprine?






20. Name four HMG- CoA reductase inhibitors.






21. Which antimicrobial classes inhibit protein synthesis at the 30S subunit? (2)






22. What microorganisms is Aztreonam not effective against?






23. What is the MOA of Ganciclovir?






24. MOA: Block DNA topoisomerases






25. Triamterene and amiloride - mechanism?






26. For Warfarin What is the Site of action






27. What are two toxicities associated with Cyclosporine?






28. What is the category - method of use - and adverse effects of Salmeterol in Asthma treatment?






29. Cocaine shares is mechanism of action with What antidepressant






30. Can Heparin be used during pregnancy?






31. Ca2+ channel blockers - site of action?






32. How does resistance to Vancomycin occur?






33. Thiazides - site of action?






34. What is the clincial use for Misoprostol?






35. Which drug(s) cause this reaction: Diabetes insipidus?






36. Which H2 Blocker has the most toxic effects and What are they?






37. What is the category - mechanism of action - and particular use of beclomethasone and prednisone in Asthma treatment?






38. Verapamil has similar action to?






39. What are four clinical uses of glucocorticoids?

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40. What is the MOA of Amantadine?






41. What is Metronidazole combined with for 'triple therapy'? Against What organism?






42. How is Amphotericin B administered for fungal meningitis?






43. Spironolactone - mechanism?






44. What are the major structural differences between Penicillin and Cephalosporin?






45. Antiarrhythmic class II- toxicity?






46. Hydralazine - class and mechanism?






47. What is the memory key for Metronidazole's clinical uses?






48. Which drug(s) cause this reaction: Tubulointerstitial Nephritis (5)?






49. What is the difference in receptor affinity of epinephrine at low doses? High doses?

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50. What is the MOA of Ribavirin?