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USMLE Step 1 Pharmacology

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What are common serious side effects of Aminoglycosides and What are these associated with?






2. Foscarnet does not require activation by a...






3. Which drug(s) cause this reaction: Adrenocortical Insufficiency






4. Antimicrobial prophylaxis for a history of recurrent UTIs






5. What anticholinesterase crosses the blood - brain - barrier?






6. Explain potency in relation to full and partial agonists(2).






7. For Warfarin What is the Route of administration






8. Adverse effects of Reserpine?






9. What type of gout is treated with Colchicine?






10. What enzyme is responsible for the production of Ach from Acetyl CoA and Choline






11. What are major side effects of Methicillin - Nafcillin - and Dicloxacillin?






12. Does Warfarin have a long - medium - or short half life?






13. Describe Phase II metabolism in liver(3)?






14. Aztreonam is not ________ with penicillins






15. What drug is given for Pneumocystis carinii prophylaxis?






16. Beta Blockers - site of action?






17. List the mechanism - clinical use - & toxicity of Cisplatin.






18. How is Leishmaniasis treated?






19. What is Niclosamide used for?






20. Are penicillinase resistant






21. What is the MOA for Metronidazole?






22. What is the main clinical use for the thrombolytics?






23. List the mechanism - clinical use - & toxicity of Tamoxifen.






24. What is the MOA of Polymyxins?






25. Can Warfarin be used during pregnancy?






26. List five common glucocorticoids.






27. What is the category of drug names ending in - tropin (e.g. Somatotropin)






28. List the specific antidote for this toxin: Digitalis






29. How do you calculate maintenance dose?






30. What is a prerequisite for Acyclovir activation?






31. List the specific antidote for this toxin: Methanol & Ethylene glycol






32. ___________ are Teratogenic






33. Which drug(s) cause this reaction: Cutaneous flushing (4)?






34. What patients are at risk for life threatening hypotension When taking Sildenafil (Viagra)?






35. What cholinomimetics might your pt be taking for his glaucoma






36. How is Acyclovir used clinically?






37. What is the mechanism of action of the glucocorticoids?






38. What is the category - method of use - and adverse effects of Salmeterol in Asthma treatment?






39. How are Interferons (INF) used clinically?

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40. What are two indirect acting adrenergic agonists?






41. What are the clinical uses for Ticlopidine - Clopidogrel?






42. Name four HMG- CoA reductase inhibitors.






43. What is the clinical use for Clomiphene?






44. How is Ribavirin used clinically?






45. What are four clinical activities of Aspirin?






46. What is the mechanism of Tacrolimus (FK506)?






47. ACE inhibitors - clinical use?






48. What is the mechanism of action of Colchicine used to treat acute gout?






49. Reserpine will block the syntheis of this drug and but not its precursor.






50. Furosemide - class and mechanism?