Test your basic knowledge |

USMLE Step 1 Pharmacology

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What is the formula for Volume of distribution (Vd)






2. What is the major side effect for Ampicillin and Amoxicillin?






3. What is an acronym to remember Anti - TB drugs?






4. What are common toxicities associated with Tetracyclines?

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5. Which drug(s) cause this reaction: Photosensitivity(3)?






6. Hydralazine - clinical use?






7. When is HIV therapy initiated?






8. What are common toxicities related to Vancomycin therapy?

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9. For Heparin What is the Ability to inhibit coagulation in vitro






10. Are Ampicillin and Amoxicillin are not...






11. MOA for Penicillin (3 answers)?






12. A 57 yo heart failure pt develops cardiac decompensation - What drug will give you adequate perfusion of his kidneys as well as tx for his Hypotension






13. In What population does Gray Baby Syndrome occur? Why?






14. MOA of Succinylcholine






15. How is Griseofulvin used clinically?






16. Which drug(s) cause this reaction: Tardive dyskinesia?






17. Which cancer drugs effect nuclear DNA (4)?






18. Which Aminoglycoside is used for Bowel Surgery ?






19. List the specific antidote for this toxin: Warfarin






20. Mannitol - mechanism?






21. What are the clinical uses for 1st Generation Cephalosporins?






22. What enzyme does Zileuton inhibit?






23. Adverse effects of Nifedipine - verapamil?






24. What is the clinical use for Clomiphene?






25. What are Aminoglycosides synergistic with?






26. Which diuretics cause acidosis?






27. What are Fluoroquinolones indicated for? (3)






28. What is the category of drug names ending in - ane (e.g. Halothane)






29. Ca2+ channel blockers - mechanism?






30. List the specific antidote for this toxin: Methanol & Ethylene glycol






31. Cautions When using Amiodarone?






32. What is the category - desired effect - and adverse effect of Isoproterenol in the treatment of Asthma?






33. Which receptors does phenylephrine act upon?






34. Which drug increases Sys BP w/o affecting Pulse Pressure






35. What is the MOA for the Azoles?






36. Decrease Digoxin dose in renal failure?






37. For Heparin What is the Treatment for overdose






38. What neurotransmitter does Amantadine affect? How does it influence this NT?






39. Hydrochlorothiazide - clinical use?






40. Why are albuterol and terbutaline effective in tx of acute asthmatic attacks?






41. How does a competitive antagonist effect an agonist?






42. What are five possible toxic effects of Aspirin therapy?

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43. Which individuals are predisposed to Sulfonamide - induced hemolysis?






44. Are not penicillinase resistant






45. What drug is used to treat Trematode/fluke (e.g. - Schistosomes - Paragonimus - Clonorchis) or Cysticercosis






46. How would you treat African Trypanosomiasis (sleeping sickness)?






47. What cholinergic inhibitor acts by directly inhibiting Ach release at the presynaptic terminal






48. What type of gout is treated with Allopurinol?






49. What are two toxicities of the Glitazones?






50. Will Hemicholinum affect the release of stored Ach during Cholinergic Stimulation