Test your basic knowledge |

USMLE Step 1 Pharmacology

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Acetazolamide - mechanism?






2. What is clinical use for Carbenicillin - Piperacillin - and Ticarcillin?






3. What drug is used during the pregnancy of an HIV+ mother? - Why?






4. What is the mechanism of Leuprolide?






5. How is Amantadine used clinically?

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6. How does dantrolene work?






7. What are two Glitazones?






8. What is the mechanism of action of the H2 Blockers?






9. What are two types of drugs that interfere with the action of Sucralfate and why?






10. What are Aminoglycosides synergistic with?






11. Name three calcium channel blockers?






12. What conditions are treated with Metronidazole?






13. What is the mechanism of action of Misoprostol?






14. What are two indirect acting adrenergic agonists?






15. List the mechanism - clinical use - & toxicity of 6 MP.






16. What is the MOA of Ribavirin?






17. What is the MOA of the RT Inhibitors?






18. What is a common side effect of Colchicine used to treat acute gout - especially When given orally?






19. What physiological effects was the Anes using Atropine to tx






20. What is the mechanism of action of Probenacid used to treat chronic gout?






21. What two vasodilators require simultaneous treatment with beta blockers to prevent reflex tachycardia and diuretics to prevent salt retention?






22. Name three Antiarrhythmic drugs in class IV.






23. Where does Griseofulvin deposit?






24. What musculo - skeletal side effects in Adults are associated with Floroquinolones?






25. Furosemide - clinical use?






26. What is the mechanism of action of Acetaminophen?






27. Acetazolamide - clinical uses?






28. Resistance mechanisms for Chloramphenicol






29. What is Metronidazole used for clinically?






30. What are the products and their toxicities of the metabolism of Ethylene Glycol by / alcohol dehydrogenase?






31. What are two toxicities of the Sulfonylureas?






32. How can Vancomycin - induced 'Red Man Syndrome' be prevented?






33. What is the mechanism of action of the Sulfonylureas?






34. What are the phases of succinylcholine neuromuscular blockade?






35. Aztreonam ________ to penicillinase






36. For Heparin What is the Site of action






37. How does Ganciclovir's toxicity relate to that of Acyclovir?






38. How are the Latent Hypnozoite (Liver) forms of Malaria (P. vivax - P.ovale) treated?






39. K+ sparing diuretics - toxicity?






40. Digitalis - site of action?






41. What is the most common cause of Pt noncompliance with Macrolides?






42. Why are albuterol and terbutaline effective in tx of acute asthmatic attacks?






43. Adverse effects of Hydrochlorothiazide?






44. What are common side effects of Amphotericin B?






45. What is the category and mechanism of action of Zileuton in Asthma treatment?






46. What are the nondepolarizing neuromuscular blocking drugs?






47. Aztreonam is not usually...






48. Adverse effect of Nitroprusside?






49. What is the MOA for the Azoles?






50. Cautions When using Amiodarone?