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USMLE Step 1 Pharmacology

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What is the MOA for Acyclovir?






2. What are two processes Corticosteroids inhibit leading to decreased inflammation?






3. What is the major side effect for Carbenicillin - Piperacillin - and Ticarcillin?






4. List the mechanism - clinical use - & toxicity of Busulfan.






5. Name the common Fluoroquinolones (6)






6. What are four unwanted effects of Clomiphene use?






7. Which drug(s) cause this reaction: Gingival hyperplasia?






8. Antiarrhythmic class IC- effects?






9. List the specific antidote for this toxin: Arsenic (all heavy metals)






10. Which cancer drugs effect nuclear DNA (4)?






11. ACE inhibitors - toxicity?






12. What patients are at risk for life threatening hypotension When taking Sildenafil (Viagra)?






13. Does Heparin have a long - medium - or short half life?






14. For Heparin What is the Lab value to monitor






15. What is used to reverse the action of Heparin?






16. What is the mechanism of action of the H2 Blockers?






17. What is the mechanism of action of Sildenafil (Viagra)?






18. Adverse effects of Methyldopa?

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19. Furosemide - clinical use?






20. ___________ are Teratogenic






21. What is an occasional side effect of Aztreonam?






22. Which drug(s) cause this reaction: Extrapyramidal side effects (3)?






23. What is the specific clinical use of Indomethacin in neonates?






24. Which antimuscarinic agents are used in producing mydriasis and cycloplegia?






25. What process does Zafirlukast interfere with?






26. Side effects of Isoniazid (INH)?






27. What are five disadvantages of Oral Contraceptives (synthetic progestins - estrogen)?






28. List the mechanism - clinical use - & toxicity of Paclitaxel.






29. Which drug(s) cause this reaction: Gray baby syndrome?






30. What is the clinical use for Heparin?






31. What is the mechanism of action of Misoprostol?






32. Resistance mechanisms for Chloramphenicol






33. As an Anes you want to use a depolarizing neuromuscular blocking drug on your pt - What do you use






34. Which drug(s) cause this reaction: SLE- like syndrome?






35. Why does NE result in bradycardia?






36. What is the effect of the Glitazones in diabetes treatment?






37. What is the difference in receptor affinity of epinephrine at low doses? High doses?

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38. What is the mechanism of Azathioprine?






39. Adverse effects of Reserpine?






40. List the specific antidote for this toxin: Amphetamine






41. Clinical use of Isoniazid (INH)?






42. What are the clinical uses for 3rd Generation Cephalosporins?






43. How would you reverse the effect of a neuromuscular blocking agent?






44. Antimicrobial prophylaxis for Syphilis






45. List the mechanism - clinical use - & toxicity of Doxorubicin.

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46. Which drug(s) cause this reaction: Pseudomembranous colitis?






47. What are two indirect acting adrenergic agonists?






48. What is a possible toxicity of Ticlopidine - Clopidogrel usage?






49. What conditions are treated with Metronidazole?






50. What is the MOA for Rifampin?







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