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USMLE Step 1 Pharmacology

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What is the mechanism of action and clinical use of the antiandrogen Flutamide?






2. How are Sulfonamides employed clinically?






3. What is the category and mechanism of action of Zileuton in Asthma treatment?






4. Which RT inhibitor causes Megaloblastic Anemia?






5. Dobutamine used for the tx of shock acts on Which receptors






6. What is the category - mechanism of action - and particular use of beclomethasone and prednisone in Asthma treatment?






7. Which RT inhibitors cause Lactic Acidosis?






8. Why would dopamine be useful in treating shock?






9. Which drug(s) cause this reaction: Gynecomastia (6)?






10. Which drug(s) cause this reaction: Oto and Nephrotoxicity (3)?






11. Antiarrhythmic class IV- toxicity?






12. Adverse effects of Captopril?






13. How would you reverse the effect of a neuromuscular blocking agent?






14. What is the category - desired effect - and possible mechanism of Theophylline in treating Asthma?






15. What is an occasional side effect of Aztreonam?






16. Does Heparin have a long - medium - or short half life?






17. What is the memory key for the effect of magnesium hydroxide overuse?






18. List the specific antidote for this toxin: Salicylates






19. Is toxicity rare or common whith Cromolyn used in Asthma prevention?






20. What drug is used to diagnose myasthenia gravis?






21. What is the clinical use for Sildenafil (Viagra)?






22. What is the possible mechanism and effect of Metformin in treating diabetes?






23. What is the mechanism of action of Misoprostol?






24. What is the only depolarizing neuromuscular blocking agent?






25. What is the MOA of Aztreonam?






26. What is the major toxic side effect of Penicillin?






27. What is the category of drug names ending in - triptyline (e.g. Amitriptyline)






28. Name common Polymyxins






29. What are common side effects of RT Inhibitors?






30. List the mechanism - clinical use - & toxicity of Bleomycin.






31. Which receptors does phenylephrine act upon?






32. Which drug(s) cause this reaction: Diabetes insipidus?






33. As an Anes you want to use a depolarizing neuromuscular blocking drug on your pt - What do you use






34. List the mechanism - clinical use - & toxicity of Cisplatin.






35. What are two types of drugs that interfere with the action of Sucralfate and why?






36. List the mechanism - clinical use - & toxicity of Prednisone.

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37. Antiarrhythmic class IB- effects?






38. Classes of antihypertensive drugs?






39. Digoxin v. Digitoxin: half life?






40. Which of these three drugs will cause a reflex bradycardia in your pt (Norepi - Epi - or Isoporterenol)






41. How would hemicholinium treatment affect cholinergic neurons?






42. For Warfarin What is the Mechanism of action






43. While at a tail gait party - you bite into a sandwich that a yellow jacket is also enjoying. Knowing your allergy to this creature - What should you do?






44. Verapamil has similar action to?






45. IV Penicillin






46. What are five toxicities associated with Tacrolimus (FK506)?






47. What are Amantadine - associated side effects?






48. Ganciclovir associated toxicities?






49. Ca2+ channel blockers - clinical use?






50. What parasites are treated with Pyrantel Pamoate (more specific)?