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USMLE Step 1 Pharmacology

Instructions:
  • Answer 50 questions in 15 minutes.
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  • Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Mannitol - contraindications?






2. Furosemide increases the excretion of What ion?






3. Mg+- clinical use?






4. Name the steps in drug approval(4)?






5. Which drug(s) cause this reaction: Gynecomastia (6)?






6. Acetazolamide - clinical uses?






7. What is a mnemonic to remember Amantadine's function?






8. What musculo - skeletal side effects in Adults are associated with Floroquinolones?






9. How can Vancomycin - induced 'Red Man Syndrome' be prevented?






10. Amprotericin B ___________ the BBB






11. Preferential action of the Ca2+ channel blockers at vascular smooth muscle?






12. Which drug(s) cause this reaction: P450 inhibition(6)?






13. Adverse effects of Guanethidine?






14. What are two indirect acting adrenergic agonists?






15. Name two LPL stimulators.






16. What drug is used to diagnose myasthenia gravis?






17. What are three possible complications of Heparin therapy?






18. What parasitic condition is treated with Ivermectin?

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19. What microorganisms is Aztreonam not effective against?






20. List the specific antidote for this toxin: Iron






21. A common side effects of Interferon (INF) treatment is?






22. What drug is given for Pneumocystis carinii prophylaxis?






23. The MOA for Chloramphenicol is?






24. What is the effect of the Glitazones in diabetes treatment?






25. What is the clinical use for Nystatin?






26. What is the category and mechanism of action of Zileuton in Asthma treatment?






27. What is the memory key for the effect of aluminum hydroxide overuse?






28. What is combined with Ampicillin - Amoxicillin - Carbenicillin - Piperacillin - and Ticarcillin to enhance their spectrum?






29. What is the category - mechanism of action - and effect of Ipratroprium in Asthma treatment?






30. What is the formula for Volume of distribution (Vd)






31. List the specific antidote for this toxin: Digitalis






32. What are Polymyxins used for?






33. What are are the Sulfonylureas (general description) and What is their use?






34. What is the category - mechanism of action - and particular use of beclomethasone and prednisone in Asthma treatment?






35. Mannitol - clinical use?






36. Name the common Azoles






37. What are toxicities associated with Chloramphenicol?






38. Which drug(s) cause this reaction: G6PD hemolysis(8)?






39. Which diuretics decrease urine Ca2+?






40. What are Fluoroquinolones indicated for? (3)






41. Adverse effects of Minoxidil?






42. Adverse effects of Hydralazine?






43. Cocaine casues vasoconstriction and local anesthesia by What mechanism






44. MOA: Block protein synthesis at 30s subunit






45. List the specific antidote for this toxin: Warfarin






46. List the specific antidote for this toxin: Arsenic (all heavy metals)






47. What is the only depolarizing neuromuscular blocking agent?






48. What are the products and their toxicities of the metabolism of ethanol by / alcohol dehydrogenase?






49. MOA: Block nucleotide synthesis






50. What is the category of drug names ending in - triptyline (e.g. Amitriptyline)







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