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USMLE Step 1 Pharmacology

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What are five toxicities associated with Tacrolimus (FK506)?






2. What is the mechanism of Leuprolide?






3. For Warfarin What is the Onset of action






4. Which drug(s) cause this reaction: Gingival hyperplasia?






5. Acetazolamide - clinical uses?






6. ADH antagonists - site of action?






7. What is the memory key for the effect of aluminum hydroxide overuse?






8. What is the MOA for the Tetracyclines?






9. Why would you use pralidoxime after exposure to an organophosphate?






10. What is the mechanism of action of Acetaminophen?






11. List the mechanism - clinical use - & toxicity of Etoposide.






12. What are two clinical uses of Azathioprine?






13. Why is Cilastatin administered with Imipenem?






14. What are three toxicities of Leuprolied?






15. What is the clinical utility of clonidine?






16. What is the formula for Clearance (CL)






17. As an Anes you want to use a depolarizing neuromuscular blocking drug on your pt - What do you use






18. What cholinomimetic is useful in the diagnosis of Myasthenia Gravis






19. What is the mecanism of action of Sucralfate?






20. Which RT inhibitors cause Lactic Acidosis?






21. MOA: Block nucleotide synthesis






22. What is the clinical use for Heparin?






23. How can the t1/2 of INH be altered?






24. What are the phases of succinylcholine neuromuscular blockade?






25. Is toxicity rare or common whith Cromolyn used in Asthma prevention?






26. For Heparin What is the Structure






27. What is the clinical use for Sildenafil (Viagra)?






28. Dobutamine used for the tx of shock acts on Which receptors






29. What are the major toxic side effects of the Cephalosporins?






30. Ca2+ channel blockers - site of action?






31. What is the mechanism of action of the Sulfonylureas?






32. Mannitol - clinical use?






33. What is the MOA of the RT Inhibitors?






34. How are Interferons (INF) used clinically?

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35. What is the mechanism of action of Colchicine used to treat acute gout?






36. The COX-2 inhibitors (celecoxib - rofecoxib) have similar side effects to the NSAIDs with What one exception?






37. Foscarnet toxicity?






38. These drugs acts indirectly by releasing strored catecholamines in the presynaptic terminal






39. What are Amantadine - associated side effects?






40. What is the category of drug names ending in - phylline (e.g. Theophylline)






41. What is the memory key for organisms treated with Tetracyclines?

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42. What cholinomimetics might your pt be taking for his glaucoma






43. Which drug(s) cause this reaction: Cutaneous flushing (4)?






44. What parasitic condition is treated with Ivermectin?

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45. Ethacrynic Acid - mechanism?






46. What are two toxicities of the Glitazones?






47. What drug is used to treat Trematode/fluke (e.g. - Schistosomes - Paragonimus - Clonorchis) or Cysticercosis






48. What is the mechanism of action of Heparin?






49. Which drug(s) cause this reaction: Cardiac toxicity?






50. Which drug(s) cause this reaction: Diabetes insipidus?