Test your basic knowledge |

USMLE Step 1 Pharmacology

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Antiarrhythmic class IV- clinical use?






2. What is the clincial use for Misoprostol?






3. What are are the Sulfonylureas (general description) and What is their use?






4. What are the four conditions in Which Omeprazole - Lansoprazole is used?






5. Which RT inhibitors cause Lactic Acidosis?






6. List the specific antidote for this toxin: Acetaminophen






7. What is the MOA of Isoniazid (INH)?






8. What is the memory key for organisms treated with Tetracyclines?

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9. What is the category of drug names ending in - azine (e.g. Chlorpromazine)






10. Name two classes of drugs for HIV therapy






11. Adverse effects of beta - blockers?






12. What are two toxicities of the Glitazones?






13. MOA: Disrupt bacterial/fungal cell membranes






14. What is the major side effect for Carbenicillin - Piperacillin - and Ticarcillin?






15. Which of these three drugs will cause a reflex bradycardia in your pt (Norepi - Epi - or Isoporterenol)






16. Which individuals are predisposed to Sulfonamide - induced hemolysis?






17. Ca2+ channel blockers - mechanism?






18. Which diuretics decrease urine Ca2+?






19. What is a possible toxicity of Ticlopidine - Clopidogrel usage?






20. What are signs of Sildenafil (Viagra) toxicity?






21. Resistance mechanisms for Cephalosporins/Penicillins






22. Do Tetracyclines penetrate the CNS?






23. What is the category of drug names ending in - tidine (e.g. Cimetidine)






24. For Heparin What is the Ability to inhibit coagulation in vitro






25. What sympathomimetic would you not prescribe for hypotension in a pt with renal artery sclerosis.






26. What is the category - desired effect - and period of use of albuterol in the treatment of Asthma?






27. What is the memory key for Metronidazole's clinical uses?






28. What are common side effects of RT Inhibitors?






29. Mg+- clinical use?






30. What is combined with Ampicillin - Amoxicillin - Carbenicillin - Piperacillin - and Ticarcillin to enhance their spectrum?






31. What is the clinical use for Nystatin?






32. Why would you give a drug like pancuronium or succinylcholine?






33. List the mechanism - clinical use - & toxicity of Nitrosureas.






34. What is the MOA for Vancomycin?






35. List the mechanism - clinical use - & toxicity of Vincristine.

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36. What enzymes are inhibited by NSAIDs - acetaminophen and COX II inhibitors?






37. Acetazolamide causes?

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38. List the mechanism - clinical use - & toxicity of Methotrexate.






39. What are the major structural differences between Penicillin and Cephalosporin?






40. What is the memory key for Isoniazid (INH) toxicity?






41. For Warfarin What is the Mechanism of action






42. What are the side effects of Rifampin?






43. Which drug(s) cause this reaction: Pulmonary fibrosis(3)?






44. Adverse effects of Loop Diuretics?






45. How would you reverse the effect of a neuromuscular blocking agent?






46. List the mechanism - clinical use - & toxicity of Etoposide.






47. Why are the Sulfonylureas inactive in IDDM (type -1)?






48. What microorganisms is Aztreonam not effective against?






49. List the mechanism - clinical use - & toxicity of Paclitaxel.






50. What is action of insulin in the liver - in muscle - and in adipose tissue?