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USMLE Step 1 Pharmacology

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Are penicillinase resistant






2. What are two mechanisms of action of Propythiouracil?






3. Common toxicities associated with Griseofulvin?






4. What is the MOA for Vancomycin?






5. What is the difference between the affinity for beta receptors between albuterol/terbutaline and dantroline?






6. Oral Penicillin






7. What is action of insulin in the liver - in muscle - and in adipose tissue?






8. What are three complications of Warfarin usage?






9. What is clinical use for Carbenicillin - Piperacillin - and Ticarcillin?






10. Which drug(s) cause this reaction: Cutaneous flushing (4)?






11. What are common side effects of Protease Inhibitors?






12. What is the category of drug names ending in - tidine (e.g. Cimetidine)






13. What is the MOA for Acyclovir?






14. What drug is used during the pregnancy of an HIV+ mother? - Why?






15. Resistance mechanisms for Tetracycline






16. Digoxin v. Digitoxin: excretion?






17. What is the clinical use for Ampicillin and Amoxicillin?






18. What are four Sulfonylureas?






19. Why would you use pralidoxime after exposure to an organophosphate?






20. Specifically - How does Foscarnet inhibit viral DNA pol?






21. What is an acronym to remember Anti - TB drugs?






22. Which drug(s) cause this reaction: Gray baby syndrome?






23. For Warfarin What is the Ability to inhibit coagulation in vitro






24. What microorganisms is Aztreonam not effective against?






25. What is the clinical use for Clomiphene?






26. Ethacrynic Acid - mechanism?






27. Clonidine is the preferred sym pathomimetic tx of HTN in pts with renal disease - why??






28. Digoxin v. Digitoxin: bioavailability?






29. What drug is used to diagnose myasthenia gravis?






30. List the specific antidote for this toxin: Lead






31. What is the memory key for Isoniazid (INH) toxicity?






32. What is the mechanism of Leuprolide?






33. Resistance mechanisms for Macrolides

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34. Which individuals are predisposed to Sulfonamide - induced hemolysis?






35. What are five possible toxic effects of Aspirin therapy?

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36. Name some common Tetracyclines (4)






37. What is Niclosamide used for?






38. ACE inhibitors - mechanism?






39. Name the common Non - Nucleoside Reverse Transcriptase Inhibitors






40. What is the category of drug names ending in - zosin (e.g. Prazosin)






41. Which drug(s) cause this reaction: Tubulointerstitial Nephritis (5)?






42. What is the mechanism of action of Probenacid used to treat chronic gout?






43. What is the category of drug names ending in - oxin (e.g. Digoxin)






44. What are the clinical uses for 1st Generation Cephalosporins?






45. Ca2+ channel blockers - mechanism?






46. List the specific antidote for this toxin: Beta Blockers






47. Loop diuretics (furosemide)- site of action?






48. What do Aminoglycosides require for uptake?






49. Does Ampicillin or Amoxicillin have a greater oral bioavailability?






50. How can Vancomycin - induced 'Red Man Syndrome' be prevented?