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USMLE Step 1 Pharmacology

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What is the category of drug names ending in - phylline (e.g. Theophylline)






2. IV Penicillin






3. While at a tail gait party - you bite into a sandwich that a yellow jacket is also enjoying. Knowing your allergy to this creature - What should you do?






4. List the mechanism - clinical use - & toxicity of Cyclophosphamide.






5. What are the side effects of Polymyxins?






6. Beta Blockers - site of action?






7. Beta Blockers - CNS toxicity?






8. Guanethidine enhances the release of Norepi?






9. What are the Anti - TB drugs?






10. What is the MOA of Griseofulvin?






11. What is a common side effect of Misoprostol?






12. List the mechanism - clinical use - & toxicity of Tamoxifen.






13. What is the mechanism of action of Misoprostol?






14. What conditions are treated with Metronidazole?






15. Cautions When using Amiodarone?






16. Which of the following would atropine administration cause? Hypothermia - bradycardia - excess salivation - dry flushed skin - or diarrhea






17. Which drug(s) cause this reaction: Diabetes insipidus?






18. What is an occasional side effect of Aztreonam?






19. What beta 2 agonist will help your 21yo Astma pt?






20. List the mechanism - clinical use - & toxicity of Paclitaxel.






21. K+ sparing diuretics - site of action?






22. Antiarrhythmic class IC- effects?






23. What are major side effects of Methicillin - Nafcillin - and Dicloxacillin?






24. What are three toxicities of Propylthiouracil?






25. List the specific antidote for this toxin: Acetaminophen






26. What cholinomimetic is useful in the diagnosis of Myasthenia Gravis






27. Acetazolamide - site of action?






28. Bretyllium - toxicity?






29. What type of gout is treated with Colchicine?






30. The COX-2 inhibitors (celecoxib - rofecoxib) have similar side effects to the NSAIDs with What one exception?






31. What is the category of drug names ending in - navir (e.g. Saquinavir)






32. What is the mechanism of action of Heparin?






33. What is the mechanism of action of Warfarin (Coumadin)?






34. Antiarrhythmic Class III- effects?






35. How would you reverse the effect of a neuromuscular blocking agent?






36. Cocaine casues vasoconstriction and local anesthesia by What mechanism






37. What is the mechanism of action of Omeprazole - Lansoprazole?






38. What antimicrobial class is Aztreonam syngergestic with?






39. MOA: Block mRNA synthesis






40. What do Aminoglycosides require for uptake?






41. Resistance mechanisms for Aminoglycosides






42. What is the memory key for the effect of aluminum hydroxide overuse?






43. What is the category - desired effect - and period of use of albuterol in the treatment of Asthma?






44. What is the category and mechanism of action of Zafirlukast in Asthma treatment?






45. What is the effect of guanethidine on adrenergic NE release?






46. Which drug(s) cause this reaction: Cinchonism (2)?






47. Which drug(s) cause this reaction: G6PD hemolysis(8)?






48. Resistance mechanisms for Macrolides

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49. What are common side effects of Protease Inhibitors?






50. How does resistance to Vancomycin occur?