Test your basic knowledge |

USMLE Step 1 Pharmacology

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What is the clinical use for Warfarin?






2. Steady state concentration is reached in __ number of half - lifes






3. List the mechanism - clinical use - & toxicity of Methotrexate.






4. What are the four conditions in Which Omeprazole - Lansoprazole is used?






5. What is the category of drug names ending in - navir (e.g. Saquinavir)






6. MOA: Block nucleotide synthesis






7. List the mechanism - clinical use - & toxicity of Doxorubicin.

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8. List the mechanism - clinical use - & toxicity of Paclitaxel.






9. What is the category of drug names ending in - triptyline (e.g. Amitriptyline)






10. How does dantrolene work?






11. What do you treat Nematode/roundworm (pinworm - whipworm) infections with?






12. For Heparin What is the Structure






13. Why would a patient with cog - wheel rigidity and a shuffling gait be given benztropine?






14. Mannitol - site of action?






15. The COX-2 inhibitors (celecoxib - rofecoxib) have similar side effects to the NSAIDs with What one exception?






16. What Sulfonamides are used for simple UTIs?






17. What are are the Sulfonylureas (general description) and What is their use?






18. What is the category of drug names ending in - cillin (e.g. Methicillin)






19. For Warfarin What is the Duration of action






20. What is the MOA for Rifampin?






21. How is Amphotericin B used clinically?






22. Which drug(s) cause this reaction: Anaphylaxis?






23. Antimicrobial prophylaxis for Syphilis






24. Acetazolamide causes?

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25. Toxic side effects of the Azoles?






26. Ethacrynic Acid - toxicity?






27. What is the mechanism of action of the Alpha - glucosidase inhibitors?






28. What is Nifurtimox administered for?

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29. What is the MOA for Metronidazole?






30. Hydrochlorothiazide - mechanism?






31. What are two types of drugs that interfere with the action of Sucralfate and why?






32. What are the Macrolides used for clinically?






33. What sympathomimetic would you not prescribe for hypotension in a pt with renal artery sclerosis.






34. Name the common Aminoglycosides (5)






35. Why is carbachol and pilocarpine useful in treatment of glaucoma?






36. Which cancer drugs effect nuclear DNA (4)?






37. What are five advantages of Oral Contraceptives (synthetic progestins - estrogen)?






38. Beta Blockers - CV toxicity?






39. What is the mechanism of action of Clomiphene?






40. List the mechanism - clinical use - & toxicity of 6 MP.






41. Triamterene and amiloride - mechanism?






42. Which Tetracycline is used in patients with renal failure? / Why?






43. What is a common side effect of Misoprostol?






44. What are the indications for using amphetamine?

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45. What is the memory key for Isoniazid (INH) toxicity?






46. What are two processes Corticosteroids inhibit leading to decreased inflammation?






47. Common toxicities associated with Griseofulvin?






48. List the specific antidote for this toxin: Anticholinesterases (organophosphate.)






49. ___________ are Teratogenic






50. Name the common Non - Nucleoside Reverse Transcriptase Inhibitors