Test your basic knowledge |

USMLE Step 1 Pharmacology

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Are Ampicillin and Amoxicillin are not...






2. What is the memory key for Metronidazole's clinical uses?






3. What can result due to antacid overuse?






4. What is the mechanism of action of Omeprazole - Lansoprazole?






5. How are Interferons (INF) used clinically?

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6. What are the side effects of Polymyxins?






7. Which drug(s) cause this reaction: Extrapyramidal side effects (3)?






8. What is the mechanism of Tacrolimus (FK506)?






9. List the mechanism - clinical use - & toxicity of 6 MP.






10. Name some common Sulfonamides (4)






11. Which diuretics decrease urine Ca2+?






12. Which drug(s) cause this reaction: Drug induced Parkinson's (4) ?






13. Ca2+ channel blockers - mechanism?






14. Name four Antiarrhythmic drugs in class III.






15. What is Imipenem always administered with?






16. Hydralazine - clinical use?






17. Which drug(s) cause this reaction: Cough?






18. List the specific antidote for this toxin: Benzodiazepines






19. While at a tail gait party - you bite into a sandwich that a yellow jacket is also enjoying. Knowing your allergy to this creature - What should you do?






20. What is Niclosamide used for?






21. What is treated with Chloroquine - Quinine - Mefloquine?






22. ___________ are Teratogenic






23. What are two clinical uses of Azathioprine?






24. Which drug(s) cause this reaction: Thrombotic complications?






25. Which drug(s) cause this reaction: Photosensitivity(3)?






26. Resistance mechanisms for Macrolides

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27. What is the category and mechanism of action of Zafirlukast in Asthma treatment?






28. How does resistance to Vancomycin occur?






29. What are two types of drugs that interfere with the action of Sucralfate and why?






30. List some specifics of lead poisoning(4)?






31. Antiarrhythmic class II- mechanism?






32. What is the chemical name for Ganciclovir?






33. What is the MOA of Isoniazid (INH)?






34. What are four thrombolytics?






35. What is the category and mechanism of action of Zileuton in Asthma treatment?






36. What do you treat Nematode/roundworm (pinworm - whipworm) infections with?






37. What is the category of drug names ending in - zosin (e.g. Prazosin)






38. What is the mechanism of action of the thrombolytics?






39. What is the loading dose formula?






40. What is the MOA of Ribavirin?






41. Thiazides - site of action?






42. Preferential action of the Ca2+ channel blockers at cardiac muscle?






43. Name three Antiarrhythmic drugs in class IB.






44. List the mechanism - clinical use - & toxicity of Cisplatin.






45. What is the MOA for the Aminoglycosides?






46. How can the toxic effects of TMP be ameliorated?






47. List five common glucocorticoids.






48. Why would a patient with cog - wheel rigidity and a shuffling gait be given benztropine?






49. How do spare receptors effect the Km?






50. What is the category of drug names ending in - tidine (e.g. Cimetidine)