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USMLE Step 1 Pharmacology

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What is Ketoconazole specifically used for?






2. For Heparin What is the Route of administration






3. Ethacrynic Acid - clinical use?






4. What is the mechanism of action of Sildenafil (Viagra)?






5. Toxicities associated with Acyclovir?






6. As an Anes you want to use a depolarizing neuromuscular blocking drug on your pt - What do you use






7. Adverse effects of Nifedipine - verapamil?






8. Antiarrhythmic class IV- primary site of action?






9. Procainamide - toxicity?






10. Why is pyridostigmine effective in the treatment of myasthenia gravis?






11. List the specific antidote for this toxin: Arsenic (all heavy metals)






12. What cholinergic inhibitor acts by directly inhibiting Ach release at the presynaptic terminal






13. How is Ganciclovir activated?






14. Adenosine - clinical use?






15. Which drug(s) cause this reaction: Disulfram - like reaction (4) ?






16. What is the major side effect for Carbenicillin - Piperacillin - and Ticarcillin?






17. What is the category of drug names ending in - azepam (e.g. Diazepam)






18. What is the effect of the Glitazones in diabetes treatment?






19. What is the mechanism of action of the glucocorticoids?






20. What antimuscarinic drug is useful for the tx of asthma






21. List the specific antidote for this toxin: Carbon monoxide






22. Which drug(s) cause this reaction: Aplastic anemia (5)?






23. For Heparin What is the Onset of action






24. What is the category of drug names ending in - terol (e.g. Albuterol)






25. What is a common side effect of Misoprostol?






26. What is the mecanism of action of Sucralfate?






27. Beta Blockers - CV toxicity?






28. Ca2+ channel blockers - mechanism?






29. What is the MOA for the Cephalosporins?






30. What beta 2 agonist will help your 21yo Astma pt?






31. Which drug(s) cause this reaction: Hepatitis?






32. List the specific antidote for this toxin: Digitalis






33. Which drug(s) cause this reaction: Extrapyramidal side effects (3)?






34. Clinical use of Isoniazid (INH)?






35. Antiarrhythmic class IB- clinical uses?






36. Secretion of What drug is inhibited by Probenacid used to treat chronic gout?






37. Bretyllium - toxicity?






38. What should not be taken with Tetracyclines? / Why?






39. MOA of Succinylcholine






40. What do Aminoglycosides require for uptake?






41. For Warfarin What is the Lab value to monitor






42. What are three complications of Warfarin usage?






43. What is the MOA for the Macrolides?






44. Which drug(s) cause this reaction: Stevens - Johnson syn. (3)?






45. MOA: Block protein synthesis at 30s subunit






46. Furosemide - toxicity? (OH DANG)






47. Which Tetracycline is used in patients with renal failure? / Why?






48. Dobutamine used for the tx of shock acts on Which receptors






49. List the mechanism - clinical use - & toxicity of Busulfan.






50. Digoxin v. Digitoxin: excretion?