Test your basic knowledge |

USMLE Step 1 Pharmacology

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. How is Griseofulvin used clinically?






2. Which of these three drugs will cause a reflex bradycardia in your pt (Norepi - Epi - or Isoporterenol)






3. Resistance mechanisms for Aminoglycosides






4. What is the difference in receptor affinity of epinephrine at low doses? High doses?

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5. How do you calculate maintenance dose?






6. For Heparin What is the Lab value to monitor






7. MOA: Block cell wall synthesis by inhib. Peptidoglycan cross - linking (7)






8. A common side effects of Interferon (INF) treatment is?






9. What cholinomimetics might your pt be taking for his glaucoma






10. What microorganisms is Aztreonam not effective against?






11. Name three K+ sparing diuretics?






12. What is the loading dose formula?






13. Which drug(s) cause this reaction: Cough?






14. What is the category - mechanism of action - and particular use of beclomethasone and prednisone in Asthma treatment?






15. What is a common side effect of Misoprostol?






16. Which diuretics increase urine K+?






17. What is the category of drug names ending in - ipramine (e.g. Imipramine)






18. What is the formula for Clearance (CL)






19. Describe first - order kinetics?






20. Mannitol - mechanism?






21. What is the main clinical use for the thrombolytics?






22. Adverse effects of Hydralazine?






23. How is Leishmaniasis treated?






24. Name the common Nucleoside Reverse Transcriptase Inhibitors






25. Hydrochlorothiazide - toxicity? (hyperGLUC - plus others)






26. What is the mechanism of Tacrolimus (FK506)?






27. List the mechanism - clinical use - & toxicity of Doxorubicin.

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28. What musculo - skeletal side effects in Adults are associated with Floroquinolones?






29. What is the chemical name for Ganciclovir?






30. Adverse effects of Methyldopa?

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31. Antiarrhythmic class IB- effects?






32. Antiarrhythmic Class III- effects?






33. What is the category of drug names ending in - ane (e.g. Halothane)






34. What are the side effects of Polymyxins?






35. What is the mechanism of action of Mifepristone (RU486)?






36. Norepi feedbacks and inhibits the presynaptic receptor by What mechanism






37. Resistance mechanisms for Chloramphenicol






38. In What population does Gray Baby Syndrome occur? Why?






39. List the specific antidote for this toxin: Tricyclic antidepressants






40. What is the mechanism of action and clinical use of the antiandrogens Ketoconazole and Spironolactone?






41. What is the category of drug names ending in - oxin (e.g. Digoxin)






42. Which of the following would atropine administration cause? Hypothermia - bradycardia - excess salivation - dry flushed skin - or diarrhea






43. What is the category of drug names ending in - operidol (e.g. Haloperidol)






44. What are three toxicities of Leuprolied?






45. What can result due to antacid overuse?






46. List the mechanism - clinical use - & toxicity of Vincristine.

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47. What are common side effects of Protease Inhibitors?






48. List the specific antidote for this toxin: Iron






49. Acetazolamide causes?

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50. ACE inhibitors - toxicity?