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USMLE Step 1 Pharmacology

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Antimicrobial prophylaxis for Gonorrhea






2. What is the mechanism of action and clinical use of the antiandrogen Flutamide?






3. What is an occasional side effect of Aztreonam?






4. MOA: Bactericidal antibiotics






5. Which RT inhibitors cause a Rash?






6. What are four Sulfonylureas?






7. Resistance mechanisms for Cephalosporins/Penicillins






8. What is the memory key for organisms treated with Tetracyclines?

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9. How does NE modulate its own release? What other neurotransmitter has this same effect?






10. Describe the MOA of Interferons (INF)






11. Ca2+ channel blockers - clinical use?






12. What do Aminoglycosides require for uptake?






13. What is the category and mechanism of action of Zafirlukast in Asthma treatment?






14. Adverse effects of Captopril?






15. Which diuretics increase urine Ca2+?






16. List the specific antidote for this toxin: Warfarin






17. What do you treat Nematode/roundworm (pinworm - whipworm) infections with?






18. What is the category - mechanism of action - and particular use of beclomethasone and prednisone in Asthma treatment?






19. Classes of antihypertensive drugs?






20. What are three toxicities of Propylthiouracil?






21. Which diuretics increase urine K+?






22. Hydrochlorothiazide - clinical use?






23. If a patient is given hexamethonium - What would happen to his/her heart rate?






24. What is the mechanism of action of Omeprazole - Lansoprazole?






25. IV Penicillin






26. Adverse effects of Minoxidil?






27. What is the category - desired effect - and adverse effect of Isoproterenol in the treatment of Asthma?






28. What additional side effects exist for Ampicillin?






29. How can Isoniazid (INH)- induced neurotoxicity be prevented?






30. Adverse effects of Hydralazine?






31. List the specific antidote for this toxin: Iron






32. What is the MOA of the RT Inhibitors?






33. How are Sulfonamides employed clinically?






34. What is the category of drug names ending in - caine (e.g. Lidocaine)






35. List the specific antidote for this toxin: Cyanide






36. What are three clinical uses of the Leuprolide?






37. For Heparin What is the Treatment for overdose






38. How is Ribavirin used clinically?






39. What is the MOA for the Cephalosporins?






40. Adverse effects of Losartan?






41. What is the MOA for Ampicillin and Amoxicillin?






42. Ibutilide - toxicity?






43. Antiarrhythmic class IA effects?






44. Antiarrhythmic class II- effects?






45. What enzyme is responsible for the production of Ach from Acetyl CoA and Choline






46. Describe Phase II metabolism in liver(3)?






47. Ethacrynic Acid - mechanism?






48. How would you reverse the effect of a neuromuscular blocking agent?






49. Name four Antiarrhythmic drugs in class III.






50. What is the category of drug names ending in - cycline (e.g. Tetracycline)