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USMLE Step 1 Pharmacology

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What are two processes Corticosteroids inhibit leading to decreased inflammation?






2. List the specific antidote for this toxin: Cyanide






3. K+- clinical use?






4. What is a Ribavirin toxicity?






5. Is toxicity rare or common whith Cromolyn used in Asthma prevention?






6. List the mechanism - clinical use - & toxicity of 5 FU.






7. List the specific antidote for this toxin: Beta Blockers






8. Ethacrynic Acid - clinical use?






9. Antiarrhythmic class II- effects?






10. What are three clinical uses of the Leuprolide?






11. What is the MOA for the Cephalosporins?






12. What are the products and their toxicities of the metabolism of ethanol by / alcohol dehydrogenase?






13. A 12yo patient was treated for a reaction to a bee sting - What drug provides the best coverage of sympathomimetic receptors?






14. What is the clinical use for Ampicillin and Amoxicillin?






15. Which drug(s) cause this reaction: Stevens - Johnson syn. (3)?






16. In What population does Gray Baby Syndrome occur? Why?






17. What is the category of drug names ending in - caine (e.g. Lidocaine)






18. List the specific antidote for this toxin: Iron






19. Mannitol - site of action?






20. ACE inhibitors - mechanism?






21. List the specific antidote for this toxin: Antimuscarinic (anticholinergic)






22. How are Sulfonamides employed clinically?






23. Cocaine casues vasoconstriction and local anesthesia by What mechanism






24. For Warfarin What is the Treatment for overdose






25. What is the clincial use for Misoprostol?






26. Guanethidine enhances the release of Norepi?






27. Digitalis - site of action?






28. What are five toxicities associated with Tacrolimus (FK506)?






29. What conditions would you use dantrolene?






30. List the specific antidote for this toxin: Methanol & Ethylene glycol






31. For Heparin What is the Ability to inhibit coagulation in vitro






32. MOA: Block protein synthesis at 50s subunit






33. The MOA for Chloramphenicol is?






34. What is the clinical use for Sildenafil (Viagra)?






35. What is a possible result of overdose of Acetaminophen?






36. MOA: Disrupt fungal cell membranes






37. What is the mechanism of action of Probenacid used to treat chronic gout?






38. What are three toxicities of Propylthiouracil?






39. MOA: Bactericidal antibiotics






40. Verapamil has similar action to?






41. Antiarrhythmic class IA effects?






42. Why is reserpine effective in treating HTN?






43. Which drug(s) cause this reaction: Drug induced Parkinson's (4) ?






44. Which drug(s) cause this reaction: SLE- like syndrome?






45. Hydralazine - toxicity?






46. What is the clinical utility of clonidine?






47. What is the most common cause of Pt noncompliance with Macrolides?






48. Adverse effects of ganglionic blockers?






49. What is Metronidazole used for clinically?






50. What two vasodilators require simultaneous treatment with beta blockers to prevent reflex tachycardia and diuretics to prevent salt retention?