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USMLE Step 1 Pharmacology

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Which drug(s) cause this reaction: Disulfram - like reaction (4) ?






2. Name two bile acid resins.






3. What is the MOA for the Macrolides?






4. What are signs of Sildenafil (Viagra) toxicity?






5. What are three unwanted effects of Mifepristone?






6. How would you treat African Trypanosomiasis (sleeping sickness)?






7. Hydralazine - clinical use?






8. What is the category of drug names ending in - azepam (e.g. Diazepam)






9. What is the lab value used to monitor the effectiveness of Warfarin therapy?






10. Cocaine shares is mechanism of action with What antidepressant






11. Antiarrhythmic class IV- primary site of action?






12. Guanethidine enhances the release of Norepi?






13. What is a possible result of overdose of Acetaminophen?






14. What is the category of drug names ending in - phylline (e.g. Theophylline)






15. What are two toxicities of the Glitazones?






16. How is Rifampin used clinically?






17. Beta Blockers - CV toxicity?






18. What are the products and their toxicities of the metabolism of Ethylene Glycol by / alcohol dehydrogenase?






19. What are two types of drugs that interfere with the action of Sucralfate and why?






20. Adverse effects of ganglionic blockers?






21. Which drug(s) cause this reaction: Hot flashes?






22. What are the clinical indications for neostigmine?






23. List the specific antidote for this toxin: Tricyclic antidepressants






24. What are four conditions in Which H2 Blockers are used clinically?






25. For Heparin What is the Site of action






26. What is the mechanism of action and clinical use of the antiandrogen Flutamide?






27. List the specific antidote for this toxin: Methanol & Ethylene glycol






28. Would blockade of muscarininc receptors in the bladder be useful in treating urinary retention?






29. Name three Antiarrhythmic drugs in class IC.






30. List the specific antidote for this toxin: Amphetamine






31. Does Heparin have a long - medium - or short half life?






32. What is the category of drug names ending in - triptyline (e.g. Amitriptyline)






33. What is the formula for Volume of distribution (Vd)






34. List the mechanism - clinical use - & toxicity of Methotrexate.






35. What is the category of drug names ending in - ipramine (e.g. Imipramine)






36. How is Foscarnet used clinically?






37. Which drug(s) cause this reaction: Anaphylaxis?






38. What is the mechanism of action of Warfarin (Coumadin)?






39. What are four clinical activities of Aspirin?






40. What is the MOA of Amantadine?






41. For Heparin What is the Route of administration






42. What is the category of drug names ending in - oxin (e.g. Digoxin)






43. What are two Alpha - glucosidase inhibitors?






44. What are the side effects of Polymyxins?






45. What are the products and their toxicities of the metabolism of ethanol by / alcohol dehydrogenase?






46. What are five disadvantages of Oral Contraceptives (synthetic progestins - estrogen)?






47. Beta Blockers - CNS toxicity?






48. Adverse effect of Nitroprusside?






49. Adverse effects of Loop Diuretics?






50. How does resistance to Vancomycin occur?