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USMLE Step 1 Pharmacology

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What can result due to antacid overuse?






2. Which drug(s) cause this reaction: Cough?






3. What is the category of drug names ending in - barbital (e.g. Phenobarbital)






4. Which Aminoglycoside is used for Bowel Surgery ?






5. What are Methicillin - Nafcillin - and Dicloxacillin used for clinically?






6. What is the memory key for Isoniazid (INH) toxicity?






7. What is the category of drug names ending in - azepam (e.g. Diazepam)






8. What is the mechanism of action of Clomiphene?






9. Toxic side effects of the Azoles?






10. What is the mechanism of action of Cyclosporine?






11. MOA: Block nucleotide synthesis






12. What is the MOA for Ampicillin and Amoxicillin?






13. Can Heparin be used during pregnancy?






14. List the specific antidote for this toxin: Beta Blockers






15. What is the category - desired effect - and possible mechanism of Theophylline in treating Asthma?






16. Resistance mechanisms for Aminoglycosides






17. These drugs acts indirectly by releasing strored catecholamines in the presynaptic terminal






18. What type of gout is treated with Colchicine?






19. A fellow passenger on a Carnival cruise ship looks pale and diaphoretic - What antimuscarinic agent would you give them?






20. Which drug(s) cause this reaction: Osteoporosis (2)?






21. ________ ae not resistant to penicillinase - - but they are less susceptible than the other Beta lactams






22. What are Amantadine - associated side effects?






23. ACE inhibitors - clinical use?






24. What are Aminoglycosides synergistic with?






25. How do the Protease Inhibitors work?






26. Cocaine casues vasoconstriction and local anesthesia by What mechanism






27. What is the MOA of Foscarnet?






28. What is the receptor affinity and clinical use of isoproterenol?






29. What antimicrobial class is Aztreonam syngergestic with?






30. MOA: Block protein synthesis at 50s subunit






31. What microorganisms is Aztreonam not effective against?






32. What is an occasional side effect of Aztreonam?






33. Which drug(s) cause this reaction: Stevens - Johnson syn. (3)?






34. Beta Blockers - CNS toxicity?






35. List the mechanism - clinical use - & toxicity of Doxorubicin.

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36. What are the indications for using amphetamine?

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37. What is the effect of norepinephrine on bp and pulse pressure?






38. List the specific antidote for this toxin: Benzodiazepines






39. What is the mecanism of action of Sucralfate?






40. Name the common Azoles






41. What is the MOA for the Azoles?






42. Secretion of What drug is inhibited by Probenacid used to treat chronic gout?






43. Which drug(s) cause this reaction: Tardive dyskinesia?






44. Does Warfarin have a long - medium - or short half life?






45. What is the clinical use for Sildenafil (Viagra)?






46. For Warfarin What is the Onset of action






47. Which antimuscarinic agents are used in producing mydriasis and cycloplegia?






48. Acetaminophen has What two clinical uses and lacks What one clinical use of the NSAIDs?






49. How is Chloramphenical used clinically?






50. MOA of Succinylcholine