Test your basic knowledge |

USMLE Step 1 Pharmacology

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Beta Blockers - BP?






2. Why are Methicillin - Nafcillin - and Dicloxacillin penicillinase resistant?






3. What are common toxicities related to Vancomycin therapy?

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4. For Heparin What is the Mechanism of action






5. Beta Blockers - site of action?






6. How are the HIV drugs used clinically?

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7. What type of gout is treated with Probenacid?






8. For Warfarin What is the Onset of action






9. A fellow passenger on a Carnival cruise ship looks pale and diaphoretic - What antimuscarinic agent would you give them?






10. Which drug(s) cause this reaction: G6PD hemolysis(8)?






11. What are two indirect acting adrenergic agonists?






12. What is the category - desired effect - and adverse effect of Isoproterenol in the treatment of Asthma?






13. What are three toxicities of Propylthiouracil?






14. What is the category - method of use - and adverse effects of Salmeterol in Asthma treatment?






15. What is the MOA of Ribavirin?






16. Adverse effect of Nitroprusside?






17. How is Rifampin used clinically?






18. Mannitol - contraindications?






19. What is the category of drug names ending in - tidine (e.g. Cimetidine)






20. Foscarnet does not require activation by a...






21. Aztreonam ________ to penicillinase






22. Acetazolamide - toxicity?






23. What are two clinical uses of Azathioprine?






24. What neurotransmitter does Amantadine affect? How does it influence this NT?






25. What is the loading dose formula?






26. What is the category of drug names ending in - terol (e.g. Albuterol)






27. Name the common Azoles






28. Name two bile acid resins.






29. Antiarrhythmic class IV- toxicity?






30. Antiarrhythmic class IV- primary site of action?






31. For Heparin What is the Site of action






32. What do you treat Nematode/roundworm (pinworm - whipworm) infections with?






33. List the specific antidote for this toxin: Cyanide






34. Cocaine shares is mechanism of action with What antidepressant






35. Which individuals are predisposed to Sulfonamide - induced hemolysis?






36. How does dantrolene work?






37. Classes of antihypertensive drugs?






38. What parasitic condition is treated with Ivermectin?

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39. Resistance mechanisms for Vancomycin






40. What enzyme is responsible for the breakdown of ACh in the synaptic cleft?






41. Antiarrhythmic class IV- effects?






42. What is the memory key for organisms treated with Tetracyclines?

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43. Which drug(s) cause this reaction: Extrapyramidal side effects (3)?






44. Ibutilide - toxicity?






45. What are the classic symptoms of cholinesterase inhibitor poisoning (parathion or other organophosphates)?






46. Acetaminophen has What two clinical uses and lacks What one clinical use of the NSAIDs?






47. What are common side effects of RT Inhibitors?






48. What drug is used to treat Trematode/fluke (e.g. - Schistosomes - Paragonimus - Clonorchis) or Cysticercosis






49. Antimicrobial prophylaxis for Syphilis






50. What is treated with Chloroquine - Quinine - Mefloquine?