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USMLE Step 1 Pharmacology

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What is the clinical use for Heparin?






2. Adverse effects of Reserpine?






3. Can Heparin be used during pregnancy?






4. Where does Griseofulvin deposit?






5. What are four Sulfonylureas?






6. Which diuretics increase urine K+?






7. Toxic side effects of the Azoles?






8. List the mechanism - clinical use - & toxicity of Methotrexate.






9. List the specific antidote for this toxin: Lead






10. Adverse effects of Nifedipine - verapamil?






11. For Warfarin What is the Lab value to monitor






12. Which H2 Blocker has the most toxic effects and What are they?






13. MOA: Bactericidal antibiotics






14. What are five disadvantages of Oral Contraceptives (synthetic progestins - estrogen)?






15. What is the memory key for the effect of magnesium hydroxide overuse?






16. How do Sulfonamides act on bacteria?






17. What is the category of drug names ending in - caine (e.g. Lidocaine)






18. Nifedipine has similar action to?






19. What are two processes Corticosteroids inhibit leading to decreased inflammation?






20. How do we stop angina?






21. What is Fluconazole specifically used for?






22. What drugs target anticholinesterase






23. How do you calculate maintenance dose?






24. What are common toxic side effects of Sulfonamides? (5)






25. ACE inhibitors - mechanism?






26. Which drug(s) cause this reaction: Anaphylaxis?






27. MOA: Disrupt fungal cell membranes






28. What are two conditions in Which COX-2 inhibitors might be used?






29. How is Leishmaniasis treated?






30. Does Warfarin have a long - medium - or short half life?






31. Name four Antiarrhythmic drugs in class IA.






32. List five common glucocorticoids.






33. MOA: Block protein synthesis at 30s subunit






34. Spironolactone - mechanism?






35. What is the mechanism of action of Acetaminophen?






36. For Warfarin What is the Mechanism of action






37. What type of patient should not take Misoprostol and why?






38. How would you treat African Trypanosomiasis (sleeping sickness)?






39. Will Hemicholinum affect the release of stored Ach during Cholinergic Stimulation






40. Which of the following would atropine administration cause? Hypothermia - bradycardia - excess salivation - dry flushed skin - or diarrhea






41. Name three calcium channel blockers?






42. What is the category of drug names ending in - azol (e.g. Ketoconazole)






43. What is the mechanism of action of Clomiphene?






44. Antiarrhythmic class IV- primary site of action?






45. What is action of insulin in the liver - in muscle - and in adipose tissue?






46. What is the category of drug names ending in - ane (e.g. Halothane)






47. Bretyllium - toxicity?






48. What is the category and mechanism of action of Zileuton in Asthma treatment?






49. For Warfarin What is the Route of administration






50. Which drug(s) cause this reaction: Atropine - like side effects?