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USMLE Step 1 Pharmacology

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Preferential action of the Ca2+ channel blockers at cardiac muscle?






2. How can Vancomycin - induced 'Red Man Syndrome' be prevented?






3. Digoxin v. Digitoxin: bioavailability?






4. List the mechanism - clinical use - & toxicity of Busulfan.






5. For Heparin What is the Ability to inhibit coagulation in vitro






6. For Heparin What is the Structure






7. Can Warfarin be used during pregnancy?






8. List the specific antidote for this toxin: Arsenic (all heavy metals)






9. Adverse effects of Clonidine?






10. What is the MOA for Methicillin - Nafcillin - and Dicloxacillin?






11. What is the category and mechanism of action of Zafirlukast in Asthma treatment?






12. What is the category of drug names ending in - zosin (e.g. Prazosin)






13. What are the side effects of Rifampin?






14. What sympathomimetic would you not prescribe for hypotension in a pt with renal artery sclerosis.






15. Which RT inhibitors cause a Rash?






16. What is the effect of norepinephrine on bp and pulse pressure?






17. What are three possible complications of Heparin therapy?






18. What do Aminoglycosides require for uptake?






19. Which drug(s) cause this reaction: Osteoporosis (2)?






20. What class of drug is echothiophate? What is its indication?






21. What are Methicillin - Nafcillin - and Dicloxacillin used for clinically?






22. Why would you use pralidoxime after exposure to an organophosphate?






23. ________ ae not resistant to penicillinase - - but they are less susceptible than the other Beta lactams






24. What is used to reverse the action of Heparin?






25. What are the clinical uses for Imipenem/cilastatin?






26. Which drug(s) cause this reaction: G6PD hemolysis(8)?






27. For Warfarin What is the Route of administration






28. What is the category of drug names ending in - pril (e.g. Captopril)






29. What is the category - desired effect - and period of use of albuterol in the treatment of Asthma?






30. What is Clindamycin used for clinically?






31. What is a prerequisite for Acyclovir activation?






32. What is the major side effect for Ampicillin and Amoxicillin?






33. How is Rifampin used clinically?






34. How is Acyclovir used clinically?






35. In What population does Gray Baby Syndrome occur? Why?






36. What is the difference between the affinity for beta receptors between albuterol/terbutaline and dantroline?






37. What are the Macrolides used for clinically?






38. How is Leishmaniasis treated?






39. Nifedipine has similar action to?






40. What is the category of drug names ending in - oxin (e.g. Digoxin)






41. Isopoterenol was given to a patient with a developing AV block - why?






42. Which diuretics cause alkalosis?






43. Which individuals are predisposed to Sulfonamide - induced hemolysis?






44. Amiodarone - toxicity?






45. What type of gout is treated with Probenacid?






46. ACE inhibitors - toxicity?






47. What is the MOA for Carbenicillin - Piperacillin - and Ticarcillin?






48. What is the MOA of Griseofulvin?






49. Furosemide - clinical use?






50. What antimuscarinic agent is used in asthma and COPD?