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USMLE Step 1 Pharmacology

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Does Warfarin have a long - medium - or short half life?






2. What is the clinical use for Heparin?






3. Hydralazine - toxicity?






4. For Warfarin What is the Structure






5. List the specific antidote for this toxin: Copper






6. Name two bile acid resins.






7. Antiarrhythmic class IV- clinical use?






8. What is the major side effect for Ampicillin and Amoxicillin?






9. What antimuscarinic drug is useful for the tx of asthma






10. Adverse effects of Captopril?






11. What is the MOA of Foscarnet?






12. What physiological effects was the Anes using Atropine to tx






13. Resistance mechanisms for Cephalosporins/Penicillins






14. Which drug(s) cause this reaction: Fanconi's syndrome?






15. What are five toxicities associated with Tacrolimus (FK506)?






16. What is the memory key for the effect of magnesium hydroxide overuse?






17. What is the MOA for Trimethoprim (TMP)?






18. What are common toxicities associated with Macrolides? (4)






19. Ca2+ channel blockers - clinical use?






20. What type of gout is treated with Allopurinol?






21. For Heparin What is the Duration of action






22. Which cancer drugs work at the level of proteins(2)?






23. For Warfarin What is the Route of administration






24. Why is Cilastatin administered with Imipenem?






25. Which drug(s) cause this reaction: Diabetes insipidus?






26. Ethacrynic Acid - toxicity?






27. Dobutamine used for the tx of shock acts on Which receptors






28. Which drug(s) cause this reaction: P450 induction(6)?






29. K+ sparing diuretics - toxicity?






30. How do the Protease Inhibitors work?






31. What are three complications of Warfarin usage?






32. Common toxicities associated with Griseofulvin?






33. Resistance mechanisms for Sulfonamides






34. What are the side effects of Rifampin?






35. What is the memory key for the action of Sildenafil (Viagra)?






36. Which drug(s) cause this reaction: Torsade de pointes (2)?






37. Your patient wants an effective drug to treat his motion sickness - What would you prescribe






38. What are the clinical indications for Azole therapy?






39. How do spare receptors effect the Km?






40. Procainamide - toxicity?






41. K+ sparing diuretics - clinical use?






42. Which Aminoglycoside is used for Bowel Surgery ?






43. What enzyme is responsible for the degredation of Ach






44. What is the category - method of use - and adverse effects of Salmeterol in Asthma treatment?






45. Foscarnet does not require activation by a...






46. Name five Antiarrhythmic drugs in class II?






47. How is Amphotericin B used clinically?






48. Quinidine - toxicity?






49. Which diuretics increase urine K+?






50. What is the mechanism of action of Omeprazole - Lansoprazole?