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USMLE Step 1 Pharmacology

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. List the specific antidote for this toxin: Iron






2. What neurotransmitter does Amantadine affect? How does it influence this NT?






3. Acetaminophen has What two clinical uses and lacks What one clinical use of the NSAIDs?






4. How can the toxic effects of TMP be ameliorated?






5. Which Tetracycline is used in patients with renal failure? / Why?






6. What is the lab value used to monitor the effectiveness of Heparin therapy?






7. How is Amphotericin B administered for fungal meningitis?






8. Decrease Digoxin dose in renal failure?






9. What is the memory key for the action of Sildenafil (Viagra)?






10. What is the effect of guanethidine on adrenergic NE release?






11. Is toxicity rare or common whith Cromolyn used in Asthma prevention?






12. What is the MOA for Carbenicillin - Piperacillin - and Ticarcillin?






13. Which drug(s) cause this reaction: Hot flashes?






14. What are two toxicities of the Sulfonylureas?






15. Mannitol - clinical use?






16. What are the four conditions in Which Omeprazole - Lansoprazole is used?






17. What is the clinical use for Warfarin?






18. Ca2+ channel blockers - mechanism?






19. Name three K+ sparing diuretics?






20. For Warfarin What is the Treatment for overdose






21. Which drug(s) cause this reaction: P450 inhibition(6)?






22. How does resistance to Vancomycin occur?






23. Does Warfarin have a long - medium - or short half life?






24. What antimuscarinic drug is useful for the tx of asthma






25. Why would you use pralidoxime after exposure to an organophosphate?






26. Which cancer drugs effect nuclear DNA (4)?






27. What is the clinical use for Ampicillin and Amoxicillin?






28. List the specific antidote for this toxin: Salicylates






29. Antiarrhythmic class II- mechanism?






30. How does dantrolene work?






31. Which diuretics decrease urine Ca2+?






32. Furosemide increases the excretion of What ion?






33. Ca2+ sensitizers'- site of action?






34. How do Sulfonamides act on bacteria?






35. What are the indications for using amphetamine?

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36. What is the most common cause of Pt noncompliance with Macrolides?






37. Toxic effects of TMP include?






38. Which drug(s) cause this reaction: Cinchonism (2)?






39. Hydralazine - toxicity?






40. What is combined with Ampicillin - Amoxicillin - Carbenicillin - Piperacillin - and Ticarcillin to enhance their spectrum?






41. Name the common Nucleoside Reverse Transcriptase Inhibitors






42. Which drug(s) cause this reaction: Disulfram - like reaction (4) ?






43. What is the mechanism of action of the Sulfonylureas?






44. What are common toxicities related to Vancomycin therapy?

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45. What drug is used during the pregnancy of an HIV+ mother? - Why?






46. Classes of antihypertensive drugs?






47. What is Metronidazole used for clinically?






48. What are common side effects of Protease Inhibitors?






49. How would you treat African Trypanosomiasis (sleeping sickness)?






50. Which drug(s) cause this reaction: Hepatitis?