Test your basic knowledge |

USMLE Step 1 Pharmacology

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What reversal agent could a Anes give to reverse the effects of Atropine






2. Why would you give a drug like pancuronium or succinylcholine?






3. Hydralazine - class and mechanism?






4. Digoxin v. Digitoxin: excretion?






5. Ibutilide - toxicity?






6. Which Tetracycline is used in patients with renal failure? / Why?






7. Which drug(s) cause this reaction: Photosensitivity(3)?






8. What are common toxicities related to Vancomycin therapy?

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9. What are the clinical uses for 3rd Generation Cephalosporins?






10. Which drug increases Sys BP w/o affecting Pulse Pressure






11. What are five possible toxic effects of Aspirin therapy?

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12. Why is carbachol and pilocarpine useful in treatment of glaucoma?






13. What is the mechanism of Azathioprine?






14. What are the products and their toxicities of the metabolism of Ethylene Glycol by / alcohol dehydrogenase?






15. What is the mechanism of action and clinical use of the antiandrogens Ketoconazole and Spironolactone?






16. Adverse effects of Minoxidil?






17. Ganciclovir associated toxicities?






18. What is the MOA of Ribavirin?






19. What is the MOA for Nystatin?






20. Decrease Digitoxin dose in renal failure?






21. What is the MOA for Trimethoprim (TMP)?






22. What are three complications of Warfarin usage?






23. Do Tetracyclines penetrate the CNS?






24. What is the effect of epinephrine infusion on bp and pulse pressure?






25. What is the mechanism of Tacrolimus (FK506)?






26. Steady state concentration is reached in __ number of half - lifes






27. What is the effect of the Glitazones in diabetes treatment?






28. What drug is used to diagnose myasthenia gravis?






29. What are the clinical uses for 2nd Generation Cephalosporins?






30. What is the MOA for the Cephalosporins?






31. What are the Anti - TB drugs?






32. What is the category of drug names ending in - cillin (e.g. Methicillin)






33. Antiarrhythmic class IA effects?






34. Decrease Digoxin dose in renal failure?






35. List the mechanism - clinical use - & toxicity of Etoposide.






36. Resistance mechanisms for Macrolides

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37. ACE inhibitors - clinical use?






38. Name two bile acid resins.






39. What are two toxicities associated with Cyclosporine?






40. Does Heparin have a long - medium - or short half life?






41. Antiarrhythmic class IC- effects?






42. IV Penicillin






43. ADH antagonists - site of action?






44. Aztreonam ________ to penicillinase






45. What is a mnemonic to remember Amantadine's function?






46. What are the major toxic side effects of the Cephalosporins?






47. What is the mechanism of action of Acetaminophen?






48. Specifically - How does Foscarnet inhibit viral DNA pol?






49. What are the clinical uses for 1st Generation Cephalosporins?






50. Name the common Azoles