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USMLE Step 1 Pharmacology

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. How does a competitive antagonist effect an agonist?






2. What are the clinical uses for Ticlopidine - Clopidogrel?






3. Verapamil has similar action to?






4. What is a possible toxicity of Ticlopidine - Clopidogrel usage?






5. What are the clinical uses for 3rd Generation Cephalosporins?






6. Resistance mechanisms for Cephalosporins/Penicillins






7. List the specific antidote for this toxin: Cyanide






8. What are Aminoglycosides used for clinically?






9. Common toxicities associated with Griseofulvin?






10. What is the clinical use for Warfarin?






11. Common side effects associated with Clindamycin include?






12. What is the most common cause of Pt noncompliance with Macrolides?






13. List the specific antidote for this toxin: Anticholinesterases (organophosphate.)






14. What are the nondepolarizing neuromuscular blocking drugs?






15. What is Metronidazole used for clinically?






16. What is the MOA for Carbenicillin - Piperacillin - and Ticarcillin?






17. Antimicrobial prophylaxis for Gonorrhea






18. What is the major toxic side effect of Penicillin?






19. K+- clinical use?






20. Furosemide - toxicity? (OH DANG)






21. The MOA for Chloramphenicol is?






22. What are two clinical uses of Azathioprine?






23. Which drug(s) cause this reaction: Neuro and Nephrotoxic?






24. How would you reverse the effect of a neuromuscular blocking agent?






25. What is the MOA of Polymyxins?






26. What are the side effects of Polymyxins?






27. Hydrochlorothiazide - toxicity? (hyperGLUC - plus others)






28. What side effect of using atropine to induce pupillary dilation would you expect?






29. What are the major toxic side effects of the Cephalosporins?






30. What is Metronidazole combined with for 'triple therapy'? Against What organism?






31. What is the clinical use of Tacrolimus (FK506)?






32. Which drug(s) cause this reaction: Gray baby syndrome?






33. How do the Protease Inhibitors work?






34. What is the category of drug names ending in - tropin (e.g. Somatotropin)






35. Which H2 Blocker has the most toxic effects and What are they?






36. What are the side effects of Rifampin?






37. Why does atropine dilate the pupil?






38. Do Tetracyclines penetrate the CNS?






39. What are five toxicities associated with Tacrolimus (FK506)?






40. What is the mechanism of action of Probenacid used to treat chronic gout?






41. What type of gout is treated with Allopurinol?






42. Which drug(s) cause this reaction: Hepatitis?






43. What is the mechanism of action of the glucocorticoids?






44. Antimicrobial prophylaxis for Syphilis






45. Nifedipine has similar action to?






46. What is the major side effect for Ampicillin and Amoxicillin?






47. Which diuretics increase urine K+?






48. What is the MOA of Aztreonam?






49. Norepi feedbacks and inhibits the presynaptic receptor by What mechanism






50. Name two classes of drugs for HIV therapy