Test your basic knowledge |

USMLE Step 1 Pharmacology

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What is the MOA for Metronidazole?






2. What is the mechanism of action of Aspirin?






3. List the specific antidote for this toxin: Iron






4. List the mechanism - clinical use - & toxicity of Tamoxifen.






5. What is the memory key involving the '4 R's of Rifampin?'






6. Antimicrobial prophylaxis for Gonorrhea






7. List the specific antidote for this toxin: Acetaminophen






8. Which drug(s) cause this reaction: P450 induction(6)?






9. When is HIV therapy initiated?






10. MOA: Disrupt bacterial/fungal cell membranes






11. What is the MOA for the Azoles?






12. Name common Polymyxins






13. What is the MOA of Amantadine?






14. Adverse effects of Methyldopa?

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15. List the mechanism - clinical use - & toxicity of Etoposide.






16. What are three toxicities of Leuprolied?






17. What do you treat Nematode/roundworm (pinworm - whipworm) infections with?






18. Which drug(s) cause this reaction: Cardiac toxicity?






19. Adverse effects of Captopril?






20. Which RT inhibitor causes Megaloblastic Anemia?






21. ___________ are Teratogenic






22. What Sulfonamides are used for simple UTIs?






23. Are Ampicillin and Amoxicillin are not...






24. List the mechanism - clinical use - & toxicity of Cyclophosphamide.






25. A 57 yo heart failure pt develops cardiac decompensation - What drug will give you adequate perfusion of his kidneys as well as tx for his Hypotension






26. How is Amphotericin B used clinically?






27. Which individuals are predisposed to Sulfonamide - induced hemolysis?






28. Adverse effects of Hydrochlorothiazide?






29. What cholinomimetics might your pt be taking for his glaucoma






30. What are the clinical uses for Aztreonam?






31. What are two mechanisms of action of Propythiouracil?






32. Which RT inhibitors cause a Rash?






33. Name two LPL stimulators.






34. What is the MOA for the Aminoglycosides?






35. The COX-2 inhibitors (celecoxib - rofecoxib) have similar side effects to the NSAIDs with What one exception?






36. Preferential action of the Ca2+ channel blockers at vascular smooth muscle?






37. How does a competitive antagonist effect an agonist?






38. What are common side effects of RT Inhibitors?






39. For Warfarin What is the Lab value to monitor






40. List the specific antidote for this toxin: Opioids






41. How does a noncompetitive antagonist effect an agonist?






42. What antimuscarinic drug is useful for the tx of asthma






43. Beta Blockers - CNS toxicity?






44. Name three calcium channel blockers?






45. Name the common Nucleoside Reverse Transcriptase Inhibitors






46. Name four Antiarrhythmic drugs in class III.






47. Are not penicillinase resistant






48. List the specific antidote for this toxin: Arsenic (all heavy metals)






49. List the mechanism - clinical use - & toxicity of Nitrosureas.






50. Which drug(s) cause this reaction: Cough?