Test your basic knowledge |

USMLE Step 1 Pharmacology

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. List the mechanism - clinical use - & toxicity of Cisplatin.






2. Mnemonic for Foscarnet?






3. List the specific antidote for this toxin: Salicylates






4. What is the main clinical use for the thrombolytics?






5. Aztreonam is not usually...






6. Which drug(s) cause this reaction: Gynecomastia (6)?






7. What are two clinical uses of Azathioprine?






8. List the mechanism - clinical use - & toxicity of Cyclophosphamide.






9. What is the MOA for Acyclovir?






10. What is the MOA for Clindamycin?






11. Furosemide increases the excretion of What ion?






12. ACE inhibitors - mechanism?






13. ___________ are Teratogenic






14. Adverse effects of beta - blockers?






15. What are the indications for using amphetamine?

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16. List the specific antidote for this toxin: Cyanide






17. How are the HIV drugs used clinically?

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18. A group of pts are rushed into the ER complaining of excessive sweating - tearing - salivation - HA - N and V - muscle twitching - difficulty breathing and diarrhea. What drug would be the most effective immediate tx






19. What is the category of drug names ending in - pril (e.g. Captopril)






20. Beta Blockers - site of action?






21. MOA: Block cell wall synthesis by inhib. Peptidoglycan cross - linking (7)






22. What is the clinical use for Penicillin?






23. Will Hemicholinum affect the release of stored Ach during Cholinergic Stimulation






24. What is the category of drug names ending in - azepam (e.g. Diazepam)






25. What do you treat Nematode/roundworm (pinworm - whipworm) infections with?






26. Adverse effects of Captopril?






27. For Warfarin What is the Treatment for overdose






28. How are the Latent Hypnozoite (Liver) forms of Malaria (P. vivax - P.ovale) treated?






29. What is used to reverse the action of Heparin?






30. What are three toxicities of Leuprolied?






31. List the mechanism - clinical use - & toxicity of Doxorubicin.

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32. Quinidine - toxicity?






33. Side effects of Isoniazid (INH)?






34. What is the mechanism of action of Acetaminophen?






35. How do the Protease Inhibitors work?






36. What is the MOA of Ganciclovir?






37. MOA: Disrupt bacterial/fungal cell membranes






38. If a patient is given hexamethonium - What would happen to his/her heart rate?






39. Which antimuscarinic agents are used in producing mydriasis and cycloplegia?






40. What is the category of drug names ending in - barbital (e.g. Phenobarbital)






41. List the specific antidote for this toxin: Benzodiazepines






42. K+- clinical use?






43. What is the clinical use for Sucralfate?






44. What is the clinical use for Ampicillin and Amoxicillin?






45. Common toxicities associated with Fluoroquinolones?






46. What is Imipenem always administered with?






47. These drugs acts indirectly by releasing strored catecholamines in the presynaptic terminal






48. What are two mechanisms of action of Propythiouracil?






49. Which drug(s) cause this reaction: Diabetes insipidus?






50. Antiarrhythmic Class III- effects?