Test your basic knowledge |

USMLE Step 1 Pharmacology

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Which drug increases Sys BP w/o affecting Pulse Pressure






2. Name two bile acid resins.






3. How do you calculate maintenance dose?






4. What conditions are treated with Metronidazole?






5. What is the MOA for Metronidazole?






6. What is the MOA of Griseofulvin?






7. What is the difference in receptor affinity of epinephrine at low doses? High doses?

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8. What is the category of drug names ending in - cillin (e.g. Methicillin)






9. ________ ae not resistant to penicillinase - - but they are less susceptible than the other Beta lactams






10. The MOA for Chloramphenicol is?






11. What is Nifurtimox administered for?

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12. Name two LPL stimulators.






13. What is the category of drug names ending in - azol (e.g. Ketoconazole)






14. What are the indications for using amphetamine?

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15. These drugs acts indirectly by releasing strored catecholamines in the presynaptic terminal






16. Resistance mechanisms for Aminoglycosides






17. Ganciclovir associated toxicities?






18. Antimicrobial prophylaxis for Gonorrhea






19. Hydralazine - clinical use?






20. What microorganisms is Aztreonam not effective against?






21. What is the memory key for organisms treated with Tetracyclines?

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22. List some specifics of lead poisoning(4)?






23. Classes of antihypertensive drugs?






24. Name the steps in drug approval(4)?






25. What are the major structural differences between Penicillin and Cephalosporin?






26. What should not be taken with Tetracyclines? / Why?






27. A common side effects of Interferon (INF) treatment is?






28. Hydrochlorothiazide - toxicity? (hyperGLUC - plus others)






29. Adverse effects of Clonidine?






30. What drug is used to diagnose myasthenia gravis?






31. What are three possible complications of Heparin therapy?






32. How would hemicholinium treatment affect cholinergic neurons?






33. Which drug(s) cause this reaction: Pseudomembranous colitis?






34. What is the effect of the Glitazones in diabetes treatment?






35. How do you treat coma in the ER (4)?






36. Which drug(s) cause this reaction: P450 induction(6)?






37. Name three Antiarrhythmic drugs in class IC.






38. How are the Latent Hypnozoite (Liver) forms of Malaria (P. vivax - P.ovale) treated?






39. What is the MOA of the RT Inhibitors?






40. Beta Blockers - BP?






41. What is the formula for Volume of distribution (Vd)






42. How is Ganciclovir used clinically?






43. What is combined with Ampicillin - Amoxicillin - Carbenicillin - Piperacillin - and Ticarcillin to enhance their spectrum?






44. While at a tail gait party - you bite into a sandwich that a yellow jacket is also enjoying. Knowing your allergy to this creature - What should you do?






45. For Warfarin What is the Site of action






46. What is the mechanism of action of NSAIDs other than Aspirin?






47. List the mechanism - clinical use - & toxicity of Tamoxifen.






48. Toxicities associated with Acyclovir?






49. Antiarrhythmic Class III- effects?






50. Ca2+ channel blockers - mechanism?