Test your basic knowledge |

USMLE Step 1 Pharmacology

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Antimicrobial prophylaxis for a history of recurrent UTIs






2. When is HIV therapy initiated?






3. How do you treat coma in the ER (4)?






4. Why would a patient with cog - wheel rigidity and a shuffling gait be given benztropine?






5. What is the MOA for Amphotericin B?






6. Describe Phase II metabolism in liver(3)?






7. Acetazolamide - site of action?






8. For Heparin What is the Mechanism of action






9. The COX-2 inhibitors (celecoxib - rofecoxib) have similar side effects to the NSAIDs with What one exception?






10. What is the category of drug names ending in - triptyline (e.g. Amitriptyline)






11. Which drug(s) cause this reaction: Extrapyramidal side effects (3)?






12. List the specific antidote for this toxin: Opioids






13. What cholinomimetic is useful in the diagnosis of Myasthenia Gravis






14. Name two LPL stimulators.






15. List the specific antidote for this toxin: Anticholinesterases (organophosphate.)






16. Furosemide - class and mechanism?






17. Which antimicrobial classes inhibit protein synthesis at the 30S subunit? (2)






18. List some specifics of lead poisoning(4)?






19. What are common toxicities associated with Tetracyclines?

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20. What is the MOA of Isoniazid (INH)?






21. Antiarrhythmic class IV- toxicity?






22. A 57 yo heart failure pt develops cardiac decompensation - What drug will give you adequate perfusion of his kidneys as well as tx for his Hypotension






23. Name three Antiarrhythmic drugs in class IC.






24. What is Nifurtimox administered for?

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25. List the mechanism - clinical use - & toxicity of Methotrexate.






26. Name three Antiarrhythmic drugs in class IB.






27. Verapamil has similar action to?






28. What is the clinical use for Sucralfate?






29. What are Fluoroquinolones indicated for? (3)






30. Which drug(s) cause this reaction: G6PD hemolysis(8)?






31. List the mechanism - clinical use - & toxicity of Prednisone.

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32. Foscarnet does not require activation by a...






33. Which Aminoglycoside is used for Bowel Surgery ?






34. Acetazolamide - mechanism?






35. What are the Macrolides used for clinically?






36. List the specific antidote for this toxin: Arsenic (all heavy metals)






37. For Warfarin What is the Treatment for overdose






38. Which cancer drugs effect nuclear DNA (4)?






39. Name three Antiarrhythmic drugs in class IV.






40. How does resistance to Vancomycin occur?






41. Which drug(s) cause this reaction: Atropine - like side effects?






42. Name three calcium channel blockers?






43. What are the products and their toxicities of the metabolism of ethanol by / alcohol dehydrogenase?






44. What are the phases of succinylcholine neuromuscular blockade?






45. Does Warfarin have a long - medium - or short half life?






46. Adverse effects of Methyldopa?

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47. What are common side effects of RT Inhibitors?






48. What is a mnemonic to remember Amantadine's function?






49. Where does Griseofulvin deposit?






50. What is the mechanism of action of Aspirin?