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USMLE Step 1 Pharmacology

Instructions:
  • Answer 50 questions in 15 minutes.
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  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What is the loading dose formula?






2. Which drug(s) cause this reaction: P450 induction(6)?






3. What are two toxicities of the Sulfonylureas?






4. What antimicrobial class is Aztreonam syngergestic with?






5. Which diuretics decrease urine Ca2+?






6. Ca2+ sensitizers'- site of action?






7. List the mechanism - clinical use - & toxicity of Etoposide.






8. What is Metronidazole combined with for 'triple therapy'? Against What organism?






9. How do you treat coma in the ER (4)?






10. What is the category of drug names ending in - tropin (e.g. Somatotropin)






11. Hydralazine - toxicity?






12. Common side effects associated with Clindamycin include?






13. Which drug(s) cause this reaction: Anaphylaxis?






14. Name some common Sulfonamides (4)






15. For Heparin What is the Onset of action






16. List some specifics of lead poisoning(4)?






17. In What population does Gray Baby Syndrome occur? Why?






18. Describe Phase I metabolism in liver(3)?






19. How do Sulfonamides act on bacteria?






20. Which drug(s) cause this reaction: Cough?






21. Why is pyridostigmine effective in the treatment of myasthenia gravis?






22. Steady state concentration is reached in __ number of half - lifes






23. Adverse effects of Nifedipine - verapamil?






24. What are common toxicities related to Vancomycin therapy?

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25. What is a Ribavirin toxicity?






26. Name five Antiarrhythmic drugs in class II?






27. Adverse effects of Losartan?






28. What cholinomimetics might your pt be taking for his glaucoma






29. What is the only depolarizing neuromuscular blocking agent?






30. What are three clinical uses of the NSAIDs?






31. Aztreonam is not usually...






32. Which antimuscarinic agents are used in producing mydriasis and cycloplegia?






33. Amiodarone - toxicity?






34. Preferential action of the Ca2+ channel blockers at cardiac muscle?






35. Acetazolamide causes?

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36. What are two clinical uses of Azathioprine?






37. What are two Alpha - glucosidase inhibitors?






38. What is the category of drug names ending in - azine (e.g. Chlorpromazine)






39. What are the clinical uses for 1st Generation Cephalosporins?






40. Which drug(s) cause this reaction: Adrenocortical Insufficiency






41. What is the category of drug names ending in - azol (e.g. Ketoconazole)






42. Mannitol - contraindications?






43. While at a tail gait party - you bite into a sandwich that a yellow jacket is also enjoying. Knowing your allergy to this creature - What should you do?






44. Which drug(s) cause this reaction: Gynecomastia (6)?






45. List the specific antidote for this toxin: Heparin






46. What enzymes are inhibited by NSAIDs - acetaminophen and COX II inhibitors?






47. How would hemicholinium treatment affect cholinergic neurons?






48. Guanethidine enhances the release of Norepi?






49. For Heparin What is the Route of administration






50. What is the mechanism of action of the thrombolytics?







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