Test your basic knowledge |

USMLE Step 1 Pharmacology

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What are the phases of succinylcholine neuromuscular blockade?






2. Ca2+ sensitizers'- site of action?






3. Mannitol - mechanism?






4. What are three clinical uses of the NSAIDs?






5. What is a sign of toxicity with the use of thrombolytics?






6. What are Polymyxins used for?






7. What microorganisms are Aminoglycosides ineffective against?






8. How do you treat coma in the ER (4)?






9. List the specific antidote for this toxin: Salicylates






10. Name three Antiarrhythmic drugs in class IB.






11. Toxic effects of TMP include?






12. Beta Blockers - BP?






13. Preferential action of the Ca2+ channel blockers at vascular smooth muscle?






14. What are Methicillin - Nafcillin - and Dicloxacillin used for clinically?






15. List the specific antidote for this toxin: Anticholinesterases (organophosphate.)






16. What are the clinical uses for Imipenem/cilastatin?






17. What is the memory key for organisms treated with Tetracyclines?

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18. Which of the following would atropine administration cause? Hypothermia - bradycardia - excess salivation - dry flushed skin - or diarrhea






19. A group of pts are rushed into the ER complaining of excessive sweating - tearing - salivation - HA - N and V - muscle twitching - difficulty breathing and diarrhea. What drug would be the most effective immediate tx






20. List the mechanism - clinical use - & toxicity of Cyclophosphamide.






21. What is Fluconazole specifically used for?






22. Which cancer drugs work at the level of proteins(2)?






23. What is the mechanism of action and clinical use of the antiandrogen Flutamide?






24. What are major side effects of Methicillin - Nafcillin - and Dicloxacillin?






25. List the specific antidote for this toxin: Beta Blockers






26. How is Vancomycin used clinically?






27. What is the formula for Volume of distribution (Vd)






28. List the specific antidote for this toxin: Carbon monoxide






29. What is the effect of epinephrine infusion on bp and pulse pressure?






30. Name four HMG- CoA reductase inhibitors.






31. What type of gout is treated with Probenacid?






32. Describe Phase I metabolism in liver(3)?






33. List the specific antidote for this toxin: Benzodiazepines






34. What are Fluoroquinolones indicated for? (3)






35. Ca2+ channel blockers - clinical use?






36. Why would dopamine be useful in treating shock?






37. What is Metronidazole used for clinically?






38. How is Amphotericin B used clinically?






39. What is the major toxic side effect of Penicillin?






40. Name two LPL stimulators.






41. Sotalol - toxicity?






42. What is the mechanism of action of Warfarin (Coumadin)?






43. Isopoterenol was given to a patient with a developing AV block - why?






44. What is the MOA for Carbenicillin - Piperacillin - and Ticarcillin?






45. What is the category of drug names ending in - operidol (e.g. Haloperidol)






46. What is clinical use for Carbenicillin - Piperacillin - and Ticarcillin?






47. Why does NE result in bradycardia?






48. Adverse effect of Nitroprusside?






49. List the specific antidote for this toxin: Arsenic (all heavy metals)






50. What is the clinical use for Warfarin?