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USMLE Step 1 Pharmacology

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Decrease Digitoxin dose in renal failure?






2. Which drug(s) cause this reaction: SLE- like syndrome?






3. How are Sulfonamides employed clinically?






4. Adverse effects of Reserpine?






5. Name the common Non - Nucleoside Reverse Transcriptase Inhibitors






6. What are two toxicities associated with Cyclosporine?






7. Hydralazine - class and mechanism?






8. The COX-2 inhibitors (celecoxib - rofecoxib) have similar side effects to the NSAIDs with What one exception?






9. What is the MOA for Ampicillin and Amoxicillin?






10. Antiarrhythmic class II- mechanism?






11. List the specific antidote for this toxin: Amphetamine






12. Which drug(s) cause this reaction: Oto and Nephrotoxicity (3)?






13. What are three unwanted effects of Mifepristone?






14. Which drug(s) cause this reaction: Disulfram - like reaction (4) ?






15. What is the mecanism of action - effective period - and ineffective period of use for Cromolyn in treating Asthma?






16. What are common side effects of RT Inhibitors?






17. Which diuretics cause acidosis?






18. Name some common Tetracyclines (4)






19. K+ sparing diuretics - toxicity?






20. List the mechanism - clinical use - & toxicity of Cyclophosphamide.






21. What are the clinical uses for Imipenem/cilastatin?






22. For Warfarin What is the Structure






23. List the mechanism - clinical use - & toxicity of Paclitaxel.






24. What is the most common cause of Pt noncompliance with Macrolides?






25. What are Methicillin - Nafcillin - and Dicloxacillin used for clinically?






26. What is the MOA for the Azoles?






27. What are the clinical indications for bethanechol?






28. What is the loading dose formula?






29. Why are the Sulfonylureas inactive in IDDM (type -1)?






30. Norepi feedbacks and inhibits the presynaptic receptor by What mechanism






31. Which drug(s) cause this reaction: Gingival hyperplasia?






32. What is a sign of toxicity with the use of thrombolytics?






33. The MOA for Chloramphenicol is?






34. What is the memory key for Isoniazid (INH) toxicity?






35. List five common glucocorticoids.






36. Triamterene and amiloride - mechanism?






37. Ethacrynic Acid - mechanism?






38. What drug is used to diagnose myasthenia gravis?






39. What parasites are treated with Pyrantel Pamoate (more specific)?






40. List the mechanism - clinical use - & toxicity of Busulfan.






41. Which receptors does phenylephrine act upon?






42. Name two organisms Vancomycin is commonly used for?






43. What is the chemical name for Ganciclovir?






44. What is the category of drug names ending in - azepam (e.g. Diazepam)






45. What is the major side effect for Ampicillin and Amoxicillin?






46. Acetazolamide causes?

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47. What is the category of drug names ending in - phylline (e.g. Theophylline)






48. What is the MOA of Polymyxins?






49. What is Fluconazole specifically used for?






50. For Warfarin What is the Route of administration