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USMLE Step 1 Pharmacology

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Preferential action of the Ca2+ channel blockers at cardiac muscle?






2. ACE inhibitors - clinical use?






3. List the specific antidote for this toxin: Amphetamine






4. What is the difference between the affinity for beta receptors between albuterol/terbutaline and dantroline?






5. Which drug(s) cause this reaction: Atropine - like side effects?






6. What are two indirect acting adrenergic agonists?






7. Antimicrobial prophylaxis for Gonorrhea






8. What is the effect of epinephrine infusion on bp and pulse pressure?






9. Are Ampicillin and Amoxicillin are not...






10. How does dantrolene work?






11. Loop diuretics (furosemide)- site of action?






12. What are nine findings of Iatrogenic Cushing's syndrome caused by glucocorticoid therapy?






13. For Warfarin What is the Ability to inhibit coagulation in vitro






14. What are the products and their toxicities of the metabolism of ethanol by / alcohol dehydrogenase?






15. Classes of antihypertensive drugs?






16. What is used to reverse the action of Heparin?






17. What are two toxicities of the Glitazones?






18. List the mechanism - clinical use - & toxicity of 6 MP.






19. For Heparin What is the Structure






20. Ca2+ channel blockers - toxicity?






21. What is the major side effect for Ampicillin and Amoxicillin?






22. ACE inhibitors - toxicity?






23. Which of epi - norepi - or isoproterenol results in bradycardia?






24. Name several common Macrolides (3)






25. What is the lab value used to monitor the effectiveness of Heparin therapy?






26. List the specific antidote for this toxin: Digitalis






27. List the specific antidote for this toxin: Benzodiazepines






28. What drug is used to diagnose myasthenia gravis?






29. Which diuretics decrease urine Ca2+?






30. Are not penicillinase resistant






31. What drugs target anticholinesterase






32. Can Warfarin be used during pregnancy?






33. List the specific antidote for this toxin: Opioids






34. What is the category of drug names ending in - olol (e.g. Propranolol)






35. How does Ganciclovir's toxicity relate to that of Acyclovir?






36. Antiarrhythmic class II- toxicity?






37. Antiarrhythmic class IV- primary site of action?






38. Antiarrhythmic class IC- effects?






39. Hydrochlorothiazide - clinical use?






40. Why would you use pralidoxime after exposure to an organophosphate?






41. What is a common side effect of Misoprostol?






42. What do Aminoglycosides require for uptake?






43. Which RT inhibitors cause a Rash?






44. What are common side effects of Amphotericin B?






45. What is the category - method of use - and adverse effects of Salmeterol in Asthma treatment?






46. Mannitol - toxicity?






47. How can the t1/2 of INH be altered?






48. What are three types of antacids and the problems that can result from their overuse?






49. What is the MOA of Foscarnet?






50. List the mechanism - clinical use - & toxicity of Nitrosureas.