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USMLE Step 1 Pharmacology

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. How is Ganciclovir activated?






2. Name the common Non - Nucleoside Reverse Transcriptase Inhibitors






3. What are four conditions in Which H2 Blockers are used clinically?






4. What is the category of drug names ending in - azepam (e.g. Diazepam)






5. What cholinomimetics might your pt be taking for his glaucoma






6. Are not penicillinase resistant






7. Acetazolamide - site of action?






8. Ca2+ channel blockers - mechanism?






9. Which individuals are predisposed to Sulfonamide - induced hemolysis?






10. What sympathomimetic would you not prescribe for hypotension in a pt with renal artery sclerosis.






11. Sotalol - toxicity?






12. How is Acyclovir used clinically?






13. Which antimicrobials inhibit protein synthesis at the 50S subunit? (4)






14. What enzyme does Zileuton inhibit?






15. What is the memory key for Metronidazole's clinical uses?






16. What is the mechanism of Azathioprine?






17. Beta Blockers - CV toxicity?






18. What is the category of drug names ending in - phylline (e.g. Theophylline)






19. Side effects of Isoniazid (INH)?






20. Ibutilide - toxicity?






21. Which antimicrobial classes inhibit protein synthesis at the 30S subunit? (2)






22. ACE inhibitors - mechanism?






23. Adverse effects of Guanethidine?






24. What is the category of drug names ending in - triptyline (e.g. Amitriptyline)






25. What is the effect of norepinephrine on bp and pulse pressure?






26. List the mechanism - clinical use - & toxicity of 5 FU.






27. Name the common Aminoglycosides (5)






28. What is the mechanism of action of Heparin?






29. What is the category of drug names ending in - caine (e.g. Lidocaine)






30. Which drug(s) cause this reaction: Neuro and Nephrotoxic?






31. What neurotransmitter does Amantadine affect? How does it influence this NT?






32. List the mechanism - clinical use - & toxicity of Paclitaxel.






33. What are three possible toxicities of NSAID usage?






34. Describe first - order kinetics?






35. What are common toxic side effects of Sulfonamides? (5)






36. What is are two clinical uses of Cyclosporine?






37. ________ ae not resistant to penicillinase - - but they are less susceptible than the other Beta lactams






38. What are two conditions in Which COX-2 inhibitors might be used?






39. What are two Glitazones?






40. Which drug(s) cause this reaction: Cutaneous flushing (4)?






41. What is the mechanism of action of Mifepristone (RU486)?






42. What are the clinical indications for Azole therapy?






43. What are the side effects of Polymyxins?






44. Decrease Digitoxin dose in renal failure?






45. What is the most common cause of Pt noncompliance with Macrolides?






46. How can Vancomycin - induced 'Red Man Syndrome' be prevented?






47. Cautions When using Amiodarone?






48. How is Rifampin used clinically?






49. Which drug(s) cause this reaction: Stevens - Johnson syn. (3)?






50. Which drug(s) cause this reaction: Cough?