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USMLE Step 1 Pharmacology

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What is the MOA for Methicillin - Nafcillin - and Dicloxacillin?






2. What is the most common cause of Pt noncompliance with Macrolides?






3. List the specific antidote for this toxin: Methemoglobin






4. What are the clinical uses for Aztreonam?






5. K+ sparing diuretics - toxicity?






6. A fellow passenger on a Carnival cruise ship looks pale and diaphoretic - What antimuscarinic agent would you give them?






7. What are five toxicities associated with Tacrolimus (FK506)?






8. What drug is given for Pneumocystis carinii prophylaxis?






9. What are two clinical uses of Azathioprine?






10. What is the category of drug names ending in - terol (e.g. Albuterol)






11. Which drug(s) cause this reaction: Oto and Nephrotoxicity (3)?






12. What are common serious side effects of Aminoglycosides and What are these associated with?






13. What type of gout is treated with Colchicine?






14. In coma situations you rule out What (7)?

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15. MOA: Block DNA topoisomerases






16. Name two LPL stimulators.






17. What is the mechanism of action and clinical use of the antiandrogen Flutamide?






18. What is the category of drug names ending in - navir (e.g. Saquinavir)






19. List the mechanism - clinical use - & toxicity of Bleomycin.






20. What is the category of drug names ending in - olol (e.g. Propranolol)






21. List the specific antidote for this toxin: Opioids






22. What is the category of drug names ending in - ipramine (e.g. Imipramine)






23. Name four Antiarrhythmic drugs in class III.






24. What are two Glitazones?






25. Which drug(s) cause this reaction: Cardiac toxicity?






26. What is the major toxic side effect of Penicillin?






27. What are three toxicities of Leuprolied?






28. Adverse effects of Guanethidine?






29. List the mechanism - clinical use - & toxicity of Nitrosureas.






30. What is the clinical use of Tacrolimus (FK506)?






31. Does Ampicillin or Amoxicillin have a greater oral bioavailability?






32. Common side effects associated with Clindamycin include?






33. What is the category of drug names ending in - cycline (e.g. Tetracycline)






34. Is toxicity rare or common whith Cromolyn used in Asthma prevention?






35. What is the mechanism of action of the glucocorticoids?






36. Antiarrhythmic class II- toxicity?






37. For Warfarin What is the Onset of action






38. What can result due to antacid overuse?






39. Why would a patient with cog - wheel rigidity and a shuffling gait be given benztropine?






40. What is the category of drug names ending in - cillin (e.g. Methicillin)






41. Antiarrhythmic class IV- clinical use?






42. Which drug(s) cause this reaction: Gingival hyperplasia?






43. K+ sparing diuretics - site of action?






44. What is the category - method of use - and adverse effects of Salmeterol in Asthma treatment?






45. Norepi feedbacks and inhibits the presynaptic receptor by What mechanism






46. Why are albuterol and terbutaline effective in tx of acute asthmatic attacks?






47. What is the category of drug names ending in - operidol (e.g. Haloperidol)






48. Would blockade of muscarininc receptors in the bladder be useful in treating urinary retention?






49. Does Heparin have a long - medium - or short half life?






50. Furosemide - clinical use?