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USMLE Step 1 Pharmacology

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Which cancer drugs work at the level of proteins(2)?






2. List the mechanism - clinical use - & toxicity of Busulfan.






3. What is the category - desired effect - and adverse effect of Isoproterenol in the treatment of Asthma?






4. What is the mechanism of action of Omeprazole - Lansoprazole?






5. What is are two clinical uses of Cyclosporine?






6. What are toxic side effects for Metronidazole?






7. What antimuscarinic drug is useful for the tx of asthma






8. How does NE modulate its own release? What other neurotransmitter has this same effect?






9. What conditions are treated with Metronidazole?






10. Which of epi - norepi - or isoproterenol results in bradycardia?






11. What is the mechanism of action of the glucocorticoids?






12. What is an occasional side effect of Aztreonam?






13. What is the category of drug names ending in - navir (e.g. Saquinavir)






14. Name four HMG- CoA reductase inhibitors.






15. What are the Anti - TB drugs?






16. Which diuretics cause alkalosis?






17. Which RT inhibitor causes Megaloblastic Anemia?






18. What is the memory key for the action of Sildenafil (Viagra)?






19. For Warfarin What is the Treatment for overdose






20. Specifically - How does Foscarnet inhibit viral DNA pol?






21. What are Aminoglycosides used for clinically?






22. How can the toxic effects of TMP be ameliorated?






23. What drug is used to diagnose myasthenia gravis?






24. What is the category of drug names ending in - azol (e.g. Ketoconazole)






25. How does botulinum toxin result in respiratory arrest?






26. What are three toxicities of Leuprolied?






27. ________ ae not resistant to penicillinase - - but they are less susceptible than the other Beta lactams






28. Ca2+ sensitizers'- site of action?






29. Which drug(s) cause this reaction: P450 inhibition(6)?






30. Beta Blockers - BP?






31. What are three complications of Warfarin usage?






32. Which drug(s) cause this reaction: Atropine - like side effects?






33. What is the chemical name for Ganciclovir?






34. Name the common Non - Nucleoside Reverse Transcriptase Inhibitors






35. As an Anes you want to use a depolarizing neuromuscular blocking drug on your pt - What do you use






36. Which drug(s) cause this reaction: Gray baby syndrome?






37. These drugs acts indirectly by releasing strored catecholamines in the presynaptic terminal






38. How is Ganciclovir activated?






39. How does a competitive antagonist effect an agonist?






40. What two vasodilators require simultaneous treatment with beta blockers to prevent reflex tachycardia and diuretics to prevent salt retention?






41. How is Vancomycin used clinically?






42. What are five possible toxic effects of Aspirin therapy?


43. Why would you use pralidoxime after exposure to an organophosphate?






44. What beta 2 agonist will help your 21yo Astma pt?






45. A common side effects of Interferon (INF) treatment is?






46. Which drug(s) cause this reaction: Drug induced Parkinson's (4) ?






47. What are four H2 Blockers?






48. List the specific antidote for this toxin: TPA & Streptokinase






49. What is the effect of TCA's on the adrenergic nerve?






50. A 12yo patient was treated for a reaction to a bee sting - What drug provides the best coverage of sympathomimetic receptors?