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USMLE Step 1 Pharmacology

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. List the specific antidote for this toxin: Methanol & Ethylene glycol






2. Ibutilide - toxicity?






3. Name several common Macrolides (3)






4. What are common toxicities associated with Tetracyclines?

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5. What is a possible toxicity of Ticlopidine - Clopidogrel usage?






6. Mannitol - clinical use?






7. What type of patient should not take Misoprostol and why?






8. What is the mechanism of action and clinical use of the antiandrogens Ketoconazole and Spironolactone?






9. Name three Antiarrhythmic drugs in class IC.






10. What are the nondepolarizing neuromuscular blocking drugs?






11. Sotalol - toxicity?






12. Adverse effects of Clonidine?






13. Mannitol - mechanism?






14. Beta Blockers - CV toxicity?






15. What are toxicities associated with Chloramphenicol?






16. What is the mechanism of action of the H2 Blockers?






17. How can Isoniazid (INH)- induced neurotoxicity be prevented?






18. Which drug(s) cause this reaction: Oto and Nephrotoxicity (3)?






19. What is the clinical use for Heparin?






20. What are the Anti - TB drugs?






21. What is the chemical name for Ganciclovir?






22. Hydrochlorothiazide - mechanism?






23. What is the MOA for Methicillin - Nafcillin - and Dicloxacillin?






24. List the mechanism - clinical use - & toxicity of Doxorubicin.

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25. What is the mechanism of action of Cyclosporine?






26. Ryanodine - site of action?






27. What is the category - method of use - and adverse effects of Salmeterol in Asthma treatment?






28. What are common toxicities associated with Macrolides? (4)






29. Antimicrobial prophylaxis for Meningococcal infection






30. What is the formula for Volume of distribution (Vd)






31. What is a common side effect of Misoprostol?






32. What is the category of drug names ending in - azepam (e.g. Diazepam)






33. Antimicrobial prophylaxis for PCP






34. Does Heparin have a long - medium - or short half life?






35. What are three toxicities of Leuprolied?






36. Which Aminoglycoside is used for Bowel Surgery ?






37. What are two types of drugs that interfere with the action of Sucralfate and why?






38. Antimicrobial prophylaxis for Gonorrhea






39. What are Aminoglycosides used for clinically?






40. What is Ketoconazole specifically used for?






41. What is the mecanism of action of the COX-2 inhibitors (celecoxib - rofecoxib)?






42. Quinidine - toxicity?






43. Digoxin v. Digitoxin: bioavailability?






44. What antimuscarinic agent is used in asthma and COPD?






45. What are three clinical uses of the NSAIDs?






46. What are the products and their toxicities of the metabolism of ethanol by / alcohol dehydrogenase?






47. What do you treat Nematode/roundworm (pinworm - whipworm) infections with?






48. Name the common Non - Nucleoside Reverse Transcriptase Inhibitors






49. What is a sign of toxicity with the use of thrombolytics?






50. Name the common Azoles