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USMLE Step 1 Pharmacology

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Which drug(s) cause this reaction: Drug induced Parkinson's (4) ?






2. Secretion of What drug is inhibited by Probenacid used to treat chronic gout?






3. Resistance mechanisms for Macrolides

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4. Digoxin v. Digitoxin: bioavailability?






5. Acetazolamide causes?

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6. Why does atropine dilate the pupil?






7. What is the enzyme inhibited - the effect of this inhibition - and the clinical use of the antiandrogren Finasteride?






8. Antiarrhythmic class IB- toxicity?






9. Are Ampicillin and Amoxicillin are not...






10. Hydralazine - class and mechanism?






11. What are the clinical uses for Aztreonam?






12. Antiarrhythmic class IV- toxicity?






13. What are three clinical uses of the Leuprolide?






14. What enzyme is responsible for the degredation of Ach






15. How is Rifampin used clinically?






16. List the mechanism - clinical use - & toxicity of Nitrosureas.






17. What are are the Sulfonylureas (general description) and What is their use?






18. Which drug(s) cause this reaction: P450 inhibition(6)?






19. List the specific antidote for this toxin: Copper






20. Which of epi - norepi - or isoproterenol results in bradycardia?






21. What are the nondepolarizing neuromuscular blocking drugs?






22. Ethacrynic Acid - clinical use?






23. What are four thrombolytics?






24. Norepi feedbacks and inhibits the presynaptic receptor by What mechanism






25. What is the major side effect for Ampicillin and Amoxicillin?






26. Amprotericin B ___________ the BBB






27. What is the category of drug names ending in - ane (e.g. Halothane)






28. List the specific antidote for this toxin: Benzodiazepines






29. MOA: Disrupt fungal cell membranes






30. What is the formula for Volume of distribution (Vd)






31. For Warfarin What is the Lab value to monitor






32. List the specific antidote for this toxin: Salicylates






33. Describe Phase I metabolism in liver(3)?






34. How is Chloramphenical used clinically?






35. K+- clinical use?






36. For Heparin What is the Mechanism of action






37. Toxic effects of TMP include?






38. For Warfarin What is the Ability to inhibit coagulation in vitro






39. What is the clinical utility of cocaine?






40. What are toxic side effects for Metronidazole?






41. What is the MOA for Vancomycin?






42. What type of gout is treated with Allopurinol?






43. What can result due to antacid overuse?






44. Oral Penicillin






45. Foscarnet does not require activation by a...






46. Classes of antihypertensive drugs?






47. Which drug(s) cause this reaction: Cardiac toxicity?






48. Which drug(s) cause this reaction: Aplastic anemia (5)?






49. What enzymes are inhibited by NSAIDs - acetaminophen and COX II inhibitors?






50. How do we stop angina?