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USMLE Step 1 Pharmacology

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What are three toxicities of Leuprolied?






2. ADH antagonists - site of action?






3. Which drug(s) cause this reaction: Photosensitivity(3)?






4. Acetaminophen has What two clinical uses and lacks What one clinical use of the NSAIDs?






5. How would you reverse the effect of a neuromuscular blocking agent?






6. What is a possible result of overdose of Acetaminophen?






7. Ca2+ channel blockers - mechanism?






8. Is toxicity rare or common whith Cromolyn used in Asthma prevention?






9. What is the category - desired effect - and period of use of albuterol in the treatment of Asthma?






10. What are the clinical uses for Ticlopidine - Clopidogrel?






11. What is the category of drug names ending in - navir (e.g. Saquinavir)






12. What are common toxicities associated with Tetracyclines?

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13. List the mechanism - clinical use - & toxicity of Etoposide.






14. List the specific antidote for this toxin: Digitalis






15. What are two Alpha - glucosidase inhibitors?






16. What is the category - mechanism of action - and particular use of beclomethasone and prednisone in Asthma treatment?






17. What is the MOA for Metronidazole?






18. What type of neurological blockade would hexamethonium create?






19. What are the clinical uses for Imipenem/cilastatin?






20. Acetazolamide - site of action?






21. Reserpine will block the syntheis of this drug and but not its precursor.






22. What is Imipenem always administered with?






23. Name four HMG- CoA reductase inhibitors.






24. What are three possible toxicities of NSAID usage?






25. What is the MOA of Imipenem?






26. MOA: Disrupt bacterial/fungal cell membranes






27. Why is there a drop in systolic - mean - and diastolic bp with infusion of isoproterenol?






28. What is Ketoconazole specifically used for?






29. Name four Antiarrhythmic drugs in class III.






30. List the specific antidote for this toxin: Cyanide






31. What is Fluconazole specifically used for?






32. What is the category of drug names ending in - caine (e.g. Lidocaine)






33. What is the mechanism of action of Clomiphene?






34. Which antimicrobial classes inhibit protein synthesis at the 30S subunit? (2)






35. Which diuretics cause acidosis?






36. What is a possible toxicity of Alpha - glucosidase inhibitors used in type -2 diabetes?






37. Common toxicities associated with Fluoroquinolones?






38. What additional side effects exist for Ampicillin?






39. What is the clinical use for Clomiphene?






40. Why are Methicillin - Nafcillin - and Dicloxacillin penicillinase resistant?






41. List the specific antidote for this toxin: Copper






42. Mg+- clinical use?






43. List the specific antidote for this toxin: Methemoglobin






44. How is Chloramphenical used clinically?






45. What is Niclosamide used for?






46. What patients are at risk for life threatening hypotension When taking Sildenafil (Viagra)?






47. Common toxicities associated with Griseofulvin?






48. Why are the Sulfonylureas inactive in IDDM (type -1)?






49. Which drug(s) cause this reaction: P450 inhibition(6)?






50. What are Aminoglycosides used for clinically?