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USMLE Step 1 Pharmacology

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What are the major toxic side effects of Imipenem/cilastatin?






2. Resistance mechanisms for Tetracycline






3. Name the Protease Inhibitors (4)






4. For Heparin What is the Ability to inhibit coagulation in vitro






5. Is resistant to penicillinase?






6. What is the mechanism of Leuprolide?






7. What is the category of drug names ending in - azine (e.g. Chlorpromazine)






8. Cautions When using Amiodarone?






9. What additional side effects exist for Ampicillin?






10. Clonidine is the preferred sym pathomimetic tx of HTN in pts with renal disease - why??






11. Hydralazine - clinical use?






12. What is the clinical use for Sildenafil (Viagra)?






13. What is the category of drug names ending in - operidol (e.g. Haloperidol)






14. Does Warfarin have a long - medium - or short half life?






15. Amiodarone - toxicity?






16. List the specific antidote for this toxin: Benzodiazepines






17. For Warfarin What is the Onset of action






18. List the specific antidote for this toxin: Arsenic (all heavy metals)






19. What parasites are treated with Pyrantel Pamoate (more specific)?






20. Adverse effects of Reserpine?






21. What is the category of drug names ending in - olol (e.g. Propranolol)






22. How is Ganciclovir used clinically?






23. What is the MOA of Aztreonam?






24. Which drug(s) cause this reaction: Tendonitis and rupture?






25. What is the category of drug names ending in - oxin (e.g. Digoxin)






26. How would hemicholinium treatment affect cholinergic neurons?






27. What are the clinical indications for Azole therapy?






28. Preferential action of the Ca2+ channel blockers at cardiac muscle?






29. For Warfarin What is the Treatment for overdose






30. Hydralazine - class and mechanism?






31. Beta Blockers - CNS toxicity?






32. Adverse effects of Hydrochlorothiazide?






33. What is the mechanism of action of Heparin?






34. What is the memory key for the effect of aluminum hydroxide overuse?






35. List the specific antidote for this toxin: Antimuscarinic (anticholinergic)






36. What is the effect of TCA's on the adrenergic nerve?






37. How can the t1/2 of INH be altered?






38. A fellow passenger on a Carnival cruise ship looks pale and diaphoretic - What antimuscarinic agent would you give them?






39. Which of these three drugs will cause a reflex bradycardia in your pt (Norepi - Epi - or Isoporterenol)






40. What microorganisms are clinical indications for Tetracycline therapy?

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41. Which drug(s) cause this reaction: Cutaneous flushing (4)?






42. List the specific antidote for this toxin: Acetaminophen






43. Isopoterenol was given to a patient with a developing AV block - why?






44. Adverse effects of Prazosin?






45. What is the category of drug names ending in - navir (e.g. Saquinavir)






46. List the specific antidote for this toxin: Beta Blockers






47. Adverse effects of Captopril?






48. What are three common NSAIDS other than Aspirin?






49. Antiarrhythmic class IV- clinical use?






50. What are common side effects of Amphotericin B?