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USMLE Step 1 Pharmacology

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What are the clinical indications for Azole therapy?






2. Which drug increases Sys BP w/o affecting Pulse Pressure






3. What are the indications for using amphetamine?

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4. How are Interferons (INF) used clinically?

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5. For Warfarin What is the Lab value to monitor






6. Which diuretics increase urine NaCl?






7. List the mechanism - clinical use - & toxicity of Nitrosureas.






8. What is the clincial use for Misoprostol?






9. Which drug(s) cause this reaction: Hepatitis?






10. Which drug(s) cause this reaction: Diabetes insipidus?






11. Toxicities associated with Acyclovir?






12. Which drug(s) cause this reaction: Atropine - like side effects?






13. What is the memory key for the action of Sildenafil (Viagra)?






14. What is Nifurtimox administered for?

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15. IV Penicillin






16. What is the memory key for Metronidazole's clinical uses?






17. Name four HMG- CoA reductase inhibitors.






18. What is the mechanism of action of Allopurinol used to treat chronic gout?






19. Name two classes of drugs for HIV therapy






20. What cholinomimetic is useful in the diagnosis of Myasthenia Gravis






21. How can the t1/2 of INH be altered?






22. How is Ganciclovir activated?






23. List the mechanism - clinical use - & toxicity of Etoposide.






24. What conditions are treated with Metronidazole?






25. Which drug(s) cause this reaction: Fanconi's syndrome?






26. Resistance mechanisms for Chloramphenicol






27. Why is carbachol and pilocarpine useful in treatment of glaucoma?






28. Name two bile acid resins.






29. What is the MOA of Foscarnet?






30. What is the category of drug names ending in - pril (e.g. Captopril)






31. Adverse effect of Nitroprusside?






32. What are the Anti - TB drugs?






33. What is the MOA for Metronidazole?






34. Name several common Macrolides (3)






35. Digoxin v. Digitoxin: bioavailability?






36. Which cancer drugs effect nuclear DNA (4)?






37. What are common toxicities related to Vancomycin therapy?

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38. List the specific antidote for this toxin: Opioids






39. List the mechanism - clinical use - & toxicity of Bleomycin.






40. What is the MOA for the Macrolides?






41. What is the effect of epinephrine infusion on bp and pulse pressure?






42. Mnemonic for Foscarnet?






43. List the specific antidote for this toxin: Digitalis






44. Classes of antihypertensive drugs?






45. MOA: Block peptidoglycan synthesis






46. While at a tail gait party - you bite into a sandwich that a yellow jacket is also enjoying. Knowing your allergy to this creature - What should you do?






47. What is the MOA for Vancomycin?






48. What drug is used to treat Trematode/fluke (e.g. - Schistosomes - Paragonimus - Clonorchis) or Cysticercosis






49. Antiarrhythmic class II- mechanism?






50. How is Chloramphenical used clinically?







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