Test your basic knowledge |

USMLE Step 1 Pharmacology

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What are the clinical uses for Aztreonam?






2. How does a noncompetitive antagonist effect an agonist?






3. What is the major side effect for Carbenicillin - Piperacillin - and Ticarcillin?






4. Antimicrobial prophylaxis for PCP






5. What is the clinical use for Clomiphene?






6. What antimuscarinic agent is used in asthma and COPD?






7. List the mechanism - clinical use - & toxicity of Nitrosureas.






8. Ethacrynic Acid - clinical use?






9. Preferential action of the Ca2+ channel blockers at cardiac muscle?






10. What is the memory key for the effect of magnesium hydroxide overuse?






11. What are three types of antacids and the problems that can result from their overuse?






12. What are common toxicities associated with Tetracyclines?

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13. What are the clinical indications for Azole therapy?






14. Acetazolamide causes?

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15. What parasites are treated with Pyrantel Pamoate (more specific)?






16. What are Aminoglycosides synergistic with?






17. Which diuretics cause alkalosis?






18. What are Methicillin - Nafcillin - and Dicloxacillin used for clinically?






19. Adverse effects of Prazosin?






20. How is Ganciclovir used clinically?






21. What is Metronidazole used for clinically?






22. Sotalol - toxicity?






23. List the specific antidote for this toxin: Warfarin






24. What is a sign of toxicity with the use of thrombolytics?






25. What is the clinical use of Mifepristone (RU486)?






26. Name the common Aminoglycosides (5)






27. List the mechanism - clinical use - & toxicity of Tamoxifen.






28. What is the category - desired effect - and possible mechanism of Theophylline in treating Asthma?






29. Triamterene and amiloride - mechanism?






30. How can Vancomycin - induced 'Red Man Syndrome' be prevented?






31. What are two indirect acting adrenergic agonists?






32. What are three possible toxicities of NSAID usage?






33. K+ sparing diuretics - site of action?






34. Why does NE result in bradycardia?






35. K+- clinical use?






36. Why is pyridostigmine effective in the treatment of myasthenia gravis?






37. What is the category - desired effect - and adverse effect of Isoproterenol in the treatment of Asthma?






38. Which antimicrobials inhibit protein synthesis at the 50S subunit? (4)






39. How is Trimethoprim used clinically?






40. Which receptors does phenylephrine act upon?






41. Explain differences between full and partial agonists(2).






42. How do you treat coma in the ER (4)?






43. Mannitol - site of action?






44. Guanethidine enhances the release of Norepi?






45. What are Fluoroquinolones indicated for? (3)






46. Which drug(s) cause this reaction: G6PD hemolysis(8)?






47. Which drug(s) cause this reaction: Atropine - like side effects?






48. MOA: Block protein synthesis at 50s subunit






49. Which drug(s) cause this reaction: Aplastic anemia (5)?






50. These drugs acts indirectly by releasing strored catecholamines in the presynaptic terminal