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USMLE Step 1 Prep

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What condition results from a deficiency in the enzyme hexosaminidase A?






2. What three cells are essential for T- cell differentiation in the thymus?






3. What three substances stimulate parietal cells?






4. What is the major Ig of the secondary immune response?






5. Are more Abs produced in a primary or a secondary immune response?






6. Name the most common type or cause - Urethritis in a young - newly sexually active individual






7. What are the five conditions associated with normochromic normocytic anemia with a normal MCV and an elevated reticulocyte count?






8. Name the compartment of the mediastinum associated with the following thoracic structures: Splanchnic nerves






9. If a sample of DNA has 30% T - What is the percent of C?

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10. In the mitochondria - what complex is needed for pyruvate carboxylase to catalyze the reaction from pyruvate to OAA?






11. In a positively skewed curve the mean is ______ than the mode.






12. What disease is associated with the HLA- DR2 and HLA- DR3 alleles






13. With What thoracic vertebra or vertebrae does rib 7 articulate?






14. What are the four reasons for hypochromic microcytic anemia with a low MCV?






15. What organism is associated with the following types of diarrhea? Watery diarrhea from beef - poultry - or gravies






16. At the base of the lung - What is the baseline intrapleural pressure - and what force does it exert on the alveoli?






17. What is the most common one? - Stromal tumor of the ovary






18. Pseudopalisades






19. What autoimmune syndrome is characterized by keratoconjunctivitis - corneal ulcers - xerostomia - and an increased risk of high - grade B- cell lymphomas? What two Ab tests are used in making the diagnosis?






20. What is the most common one? - Site for atherosclerotic plaques in the abdominal aorta






21. When does cortisol secretion peak?






22. What protozoal parasite forms flasked - shaped lesions in the duodenum - is transmitted via fecal - oral route - and is commonly seen in campers who drank stream water?






23. What is the only DNA virus that does not replicate its DNA in the nucleus of the host cell?






24. How many high - energy bonds are used to activate an AA?






25. Protein production - bile secretion - detoxification - conjugation - and lipid storage.






26. What cestode causes cysticercosis?






27. What part of the heart forms x Posterior wall?






28. Name the antimicrobial agent whose major side effect is listed - Teratogenicity






29. What negative sense RNA virus is associated with intracytoplasmic inclusion bodies called Negri bodies?






30. Name these cluster A personality disorders: x Odd - strange; has magical thinking; socially isolated - paranoid - lacks close friends; has incongruous affect






31. Name the cancer associated with the following oncogenes. (Some may have more than one answer) x Ki - ras and erb -2






32. What does hepatitis D virus need from hepatitis B virus to be infective?






33. Name the hormone






34. In an adult - Where does the spinal cord terminate and What is it called?






35. What is the term for days 15 to 28 in the female cycle?






36. Name the type of regeneration (i.e. - labile - stable - or permanent) based on the following examples - Smooth muscle






37. What happens to V/Q ratio if a thrombus is lodged in the pulmonary artery?






38. What syndrome causes inability to concentrate - easy distractibility - apathy - and regression to an infantile suckling or grasping reflex?






39. What attaches to protons and allows them to enter into the mitochondria without going through the ATP- generating system?






40. What maintains the osmotic gradient that is critical to the concentrating ability of the kidney?






41. What is the most common one? - Type of melanoma






42. Indicates the patient has active pulmonary disease.






43. What class of drugs is used in the treatment of demineralization of the bone?






44. What occurs when the lower esophageal sphincter fails to relax during swallowing due to abnormalities of the enteric nervous plexus?






45. What is the major hormone produced in the following areas of the adrenal cortex? - Zona fasciculata






46. What is the term for panhypopituitarism secondary to ischemic necrosis and hypotension postpartum?






47. Name the associated chromosome - Edward syndrome






48. What is the most common one? - Cardiac anomaly in children






49. Will a unilateral lesion in the spinothalamic tract result in a contralateral or ipsilateral loss of pain and temperature?






50. What type of potential is characterized as being an all - or - none response - propagated and not summated?