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USMLE Step 1 Prep

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. In what organelle does the TCA cycle occur?






2. What disorder is due to a deficiency in tyrosinase?






3. What is the drug of choice for steroid - induced osteoporosis?






4. What two Ags must be positive for a patient to have chronic active hepatitis?






5. What cestode causes cysticercosis?






6. What pathology involves excessive fibrosis throughout the body via increased fibroblast activity - occurs in women more than men - and is most commonly seen in the third to the fifth decade?






7. What disorder causes joint stiffness that worsens with repetitive motion - crepitus - effusions - and swelling and commonly affects the knees - hips - and spine?






8. What is the size of a positive PPD test for the following? (Reactive) x Recent immigrant from India






9. What happens to the tonicity of the urine with increased ADH secretion?






10. What syndrome is associated with the following brainstem lesions? - Contralateral corticospinal and medial lemniscus tract deficits and an ipsilatera medial strabismus secondary to a lesion in CN VI






11. What is the primary predisposing factor for vascular dementia?






12. With which CN are preganglionic parasympathetic axons arising from the Edinger - Westphal nucleus associated?






13. What three muscles constitute the erector spinae?

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14. What is the most common one? - Location of ependymomas in children






15. What linkage of complex CHOs does pancreatic amylase hydrolyze? What three complexes are formed?






16. What is the effect of T3 on heart rate and cardiac output?






17. What are the three main components of amyloid?






18. Name the associated chromosome - Neurofibromatosis type 1






19. What IV- only agent inhibits water reabsorption in the PCTs and is used to treat increased intracranial pressure - increased intraocular pressure - and acute renal failure?






20. What area of the lymph node contains germinal centers?






21. Which class of antiarrhythmics blocks sodium channels?






22. What is the name of the process in which cells migrate toward an attractant along a concentration gradient?






23. Is the hydrophobic or hydrophilic end of the phospholipids of the cell membrane facing the aqueous environment?






24. What nerves provide sensory innervation above the vocal cords? Below the vocal cords?






25. What vessels carry deoxygenated blood into the lungs from the right ventricle?






26. On the venous pressure curve - What do the following waves represent? - C wave?






27. Is splenomegaly more commonly associated with intravascular or extravascular hemolysis?






28. Are the following conditions associated with a negative or positive nitrogen balance? - Kwashiorkor






29. What hormone is characterized by the following renal effects? - Calcium excretion - phosphate excretion






30. Where are the LMN cell bodies of the corticospinal tract?






31. What facultative intracellular fungus is associated with hepatosplenomegaly?






32. Name the cancer associated with the following chemical agents. (Some may have more than one answer.) x Asbestos






33. Which region of the variable domain comprises the Ag - binding site of the Ab?






34. Name the antidote - Warfarin






35. How many carbons do androgens have?






36. If a patient with a cerebellar lesion has nystagmus - which way is the fast component directed - toward or away from the lesion?






37. What is the name of the T cell - rich area of the lymph node?






38. What is the term for the difference between systolic and diastolic pressures?






39. What are the three C's of a TCAD overdose?






40. What two ligaments of the uterus are remnants of the gubernaculum?






41. Name the type of graft described by these transplants: x From one person to the next (the same species)






42. What type of fiber or fibers are carried in (answer motor - sensory - or both) x Ventral rami?






43. Which class of antiarrhythmics are Beta- blockers?






44. What picornavirus is associated with hand - foot - and - mouth disease?






45. A 20-year - old college student has fever - grey- white membranes over the tonsils - posterior auricular lymphadenitis - and hepatosplenomegaly. What is your diagnosis? What test do you order to confirm your diagnosis?






46. What is the term for the potential difference across a cell membrane?






47. Are the following responses associated with histamines H1 or H2 receptor activation? - Inotropic action and automaticity






48. What pituitary hormone is inhibited during sleep?






49. What is the term for the difference between the highest and the lowest score in a population?






50. What three factors do Sertoli cells produce for normal male development?