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USMLE Step 1 Prep

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What disease involves microcephaly - mental retardation - cleft lip or palate - and dextrocardia?






2. In MHC class II molecules - what chain blocks access to the peptide - binding groove during transportation within the cell - ensuring that the MHC class II- peptide complex is transported to the surface?






3. Are the following responses associated with histamines H1 or H2 receptor activation? - Edema






4. Are salivary secretions hypertonic - hypotonic - or isotonic?






5. Is irreversible






6. What Ig mediates ADCC via K cells - opsonizes - and is the Ig of the secondary immune response?






7. Name the end product or products: x Fatty acid synthesis






8. Name the antidote - Benzodiazepines






9. What are the two reasons for megaloblastic anemia with elevated MCV?






10. What benign bone tumor is associated with Gardner syndrome?






11. What is the renal compensation mechanism for alkalosis?






12. What is the period between going to bed and falling asleep called?






13. What chromosome is associated with the AR form of SCID?






14. What two ligaments of the uterus are remnants of the gubernaculum?






15. Can incidence - prevalence - and cause and effect be assessed in x Cross - sectional studies?






16. What enzyme is deficient in hereditary protoporphyria?






17. What cells of the epidermis carry the pigment melanin?






18. What is the vector of African sleeping sickness?






19. What type of scale is graded into equal increments - showing not only any difference but how much?






20. Which organism causes trench fever?






21. What embryonic structure forms the following adult structures? - Collecting ducts - calyces - renal pelvis - and ureter






22. Is a membranous septal defect more commonly interventricular or interatrial?






23. What type of Ag do T cells recognize?






24. What is the term for the appearance of the kidney in malignant hypertension (it has petechiae on its surface)?






25. What type of foods should patients taking MAOIs avoid? Why?






26. What is the only antifungal agent to penetrate CSF?






27. What urinary metabolite is elevated in pheochromocytoma?






28. A patient goes to the ER with abdominal cramps - vomiting - diarrhea - and sweating less than 24 hours after eating potato salad at a picnic; What is the most likely responsible organism?






29. Induces the cytochrome P-450 enzymes.






30. What size ribosomes do fungi have?






31. What type of fiber or fibers are carried in (answer motor - sensory - or both) x Dorsal rami?






32. What is the name for failed recanalization of the duodenum resulting in polyhydramnios - bile - containing vomitus - and a distended stomach?






33. What body fluid preferentially breaks down esters?






34. From What aortic arch are the following structures derived?






35. What organ is responsible for the elimination of excess nitrogen from the body?






36. What segment of the nephron has the highest concentration of inulin? Lowest concentration of inulin?

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37. How can a deficiency in adenosine deaminase be a bone marrow suppressor?






38. What percentage of children born to HIV- positive mothers will test positive for HIV at birth?






39. T cells can recognize - bind - and internalize...






40. A schizophrenic patient who is taking haloperidol is brought to your ER with muscle rigidity - a temperature of 104






41. Name the primary vesicle the following structures are derived from (proencephalon - mesencephalon - or rhombencephalon) - Cerebral hemispheres






42. RBC casts in the urine






43. Name the product or products of arachidonic acid: x Vasoconstriction and platelet aggregation produced by platelets






44. What maintains the osmotic gradient that is critical to the concentrating ability of the kidney?






45. What cell surface marker is found on blood B cells?






46. What two receptors in the chemoreceptor trigger zone lead to vomiting when stimulated?






47. What negative sense RNA virus is associated with cough - coryza - and conjunctivitis with photophobia?






48. What two drugs - when mixed - can lead to malignant hyperthermia?






49. Multiple pregnancies - early age of intercourse - multiple sexual partners - OCP use - smoking - HIV - and STDs.






50. Name the MCC of death - In diabetic individuals