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USMLE Step 1 Prep

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. A Japanese man has weight loss - anorexia - early satiety - epigastric abdominal pain - and a palpable left supraclavicular lymph node. On endoscopy you find a large - irregular ulcer with elevated margins on the lesser curvature of the stomach. What






2. What type of bilirubin is found in neonatal jaundice?






3. What determines the overall force generated by the ventricular muscle during systole?






4. Name the aphasia based on these characteristics: x Both Broca's and Wernicke's areas damaged by lesion in the presylvian speech area; trouble repeating statements; poor comprehension with telegraphic speech






5. What is the only DNA virus that has the reverse transcriptase enzyme?






6. What is the most common one? - Helminthic parasite worldwide






7. What happens to free hormone levels when the liver decreases production and release of binding proteins?






8. Name the cerebral vessel associated with the following vascular pathologies - Epidural hemorrhage






9. Influenza - Vibrio cholera - hepatitis A - rabies - and adenovirus.






10. Are elevated alkaline phosphatase and decreased phosphorus and calcium levels more consistent with osteoporosis or osteomalacia?






11. Name the DNA virus: x Circular dsDNA; naked; icosahedral; replicates in the nucleus






12. What is the most common one? - Cardiac anomaly in Turner syndrome






13. What bacterium found in poorly preserved canned food causes flaccid paralysis?






14. There is an inverse relationship between fat content and...






15. Which dimorphic fungus is found as Arthroconidia in desert sand of the southwestern United States (e.g. - San Joaquin Valley)?






16. What is the antidote for organophosphate ingestion?






17. What two glycolytic enzymes catalyze the substrate - level phosphorylations?






18. Name the most common one - Heart defect in Down syndrome






19. Which IgG cannot activate complement?






20. What is the term to describe homosexuals who x Are comfortable with their own person and agree with their sense of self?






21. What organ is responsible for the elimination of excess nitrogen from the body?






22. Which drug is used to treat opioid withdrawal - ADHD - and sometimes Tourette's syndrome?






23. Do local anesthetics bind to the activated or inactivated sodium channels?






24. What bonds are broken by exonucleases?

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25. What viral infection is associated with black vomit?






26. What P value defines whether the hull hypothesis should or should not be rejected?






27. Which overdose carries a higher mortality rate - that of benzodiazepines or barbiturates?






28. What hormone is secreted by the placenta late in pregnancy - stimulates mammary growth during pregnancy - mobilizes energy stores from the mother so that the fetus can use them - and has an amino acid sequence like GH?






29. Which centrally acting a2- adrenergic agonist is used in the treatment protocol of opioid withdrawal?






30. What is the main inhibitor of pyruvate dehydrogenase?






31. What are the following changes seen in the luminal fluid by the time it leaves the PCT of the nephron? - Percentage of Na+ - Cl - - K+ left in the lumen






32. What is the most common primary malignant tumor in bone?






33. Which penicillin can cause interstitial nephritis?






34. What is the region of the fallopian tube where fertilization most commonly occurs?






35. Name the type of regeneration (i.e. - labile - stable - or permanent) based on the following examples - Osteoblasts






36. Which streptococcal species is characterized by being catalase negative - turning bile esculin agar black - producing a positive PYR test - and resulting in biliary and urinary tract infections?






37. Name the 10 retroperitoneal organs.






38. How early can a pregnancy be detected by hCG assays in the blood? In urine?






39. What AR disorder is due to a deficiency in glycoprotein IIb - IIIa - resulting in a defect in platelet aggregation?






40. Name the most common type or cause - Sudden cardiac death






41. What medication is a PGE1 analog that results in increased secretions of mucus and HCO3- in the GI tract?






42. Why is the apex of the lung hypoventilated when a person is standing upright?






43. Are the following parameters associated with an obstructive or restrictive lung disorder: decreased FEV1 - FVC - peak flow - and FEV1/FVC; increased TLC - FRC - and RV?






44. What artery is formed by the union of the two vertebral arteries?






45. What are the four most common causes of femoral head necrosis?






46. What is the treatment for nephrogenic diabetes insipidus induced by lithium?






47. Are antibiotics helpful in treating a disease caused by a prion?






48. What microaerophile is a motile gram - negative curved rod with polar flagella that causes infectious diarrhea at low doses (<500)?






49. What two muscles do you test to see whether CN XI is intact?






50. What is the only site in the body that uses M1 receptors?