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USMLE Step 1 Prep

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Name the type of mutation: x Unequal crossover in meiosis with loss of protein function






2. Name the cancer associated with the following chemical agents. (Some may have more than one answer.) x Naphthylamine






3. What oral antifungal agent is used to treat dermatophyte infections by disrupting microtubule structure and depositing keratin?






4. Name the compartment of the lower extremity and the nerve based on its movements - Plantar flex the foot and evert the foot






5. What are the following changes seen in the luminal fluid by the time it leaves the PCT of the nephron? - Percentage of Na+ - Cl - - K+ left in the lumen






6. What disorder is defined by inability of the lower esophageal sphincter to relax with swallowing and a bird beak barium swallow result?






7. Name the area of the cerebral cortex with the function described: x Skill - based memory - verbal recall - balance - refined voluntary movements






8. What phase of the female reproductive cycle is 14 days long?






9. Name the compartment of the mediastinum associated with the following thoracic structures: Vagus nerve






10. In what stage of psychosexual development - according to Freud - do children resolve the Oedipus complex?






11. Which class of diuretics is used to treat metabolic acidosis - acute mountain sicknesses - and glaucoma and to aid in the elimination of acidic drug overdoses?






12. What hormone excess produces adrenal hyperplasia?






13. What tumor is derived from primitive streak remnants and often contains bone - hair - or other tissue types?






14. Name the compartment of the mediastinum associated with the following thoracic structures: Aortic arch






15. What AD disease is associated with chromosome 4p; does not present until the person is in his or her 30s; and involves atrophy of the caudate nucleus - dilatation of the lateral and third ventricles - and signs of extrapyramidal lesions?






16. What is the most common form of non - Hodgkin lymphoma in the United States?






17. What are the two precursors of heme?






18. What enzyme of the TCA cycle catalyzes the production of the following: x NADH (hint: 3 enzymes)






19. What wave is the cause of the following venous pulse deflections? - The contraction of the right atrium






20. If the family member of a patient asked you to withhold information - would you?






21. What is the pancreatic action of CCK?






22. What are the three end products of amylase digestion?






23. Does the zygote divide mitotically or meiotically?






24. Name the associated chromosomal translocation - Adult familial polyposis






25. Name the hypochromic microcytic anemia based on the following laboratory values - Decreased iron - percent saturation - and ferritin; increased TIBC






26. What antihypertensive agent produces cyanide and thiocyanate as byproducts?






27. What happens to dopamine levels when we awaken?






28. Which hepatitis B serology markers






29. Serum concentration of what substance is used as a clinical measure of a patient's GFR?






30. What cells of the epidermis carry the pigment melanin?






31. How many pairs of spinal nerves are associated with x Coccygeal vertebrae?






32. What hypothalamic hormone is synthesized in the preoptic nucleus?






33. What is the only trematode that is not hermaphroditic?






34. What are the glycoprotein receptors that platelets and fibrinogen cross - link to when forming a thrombus?






35. Metformin is contraindicated in ________ because of weight gain as its side effect.






36. What is the most common one? - Location of a duodenal ulcer






37. Early menses - late menopause - history of breast cancer - obesity - and multiparity.






38. What protein allows Mycoplasma to attach to the respiratory epithelium?






39. Name the Plasmodium species based on the following information:No persistent liver stage or relapse; blood smear shows rosette schizonts; 72- hour fever spike pattern






40. What type of erythema do you see in x Rheumatic fever?






41. What enzyme of the purine salvage pathway is deficient in the following? - Selective T- cell immunodeficiency






42. What three bacteria are positive to quellung reactive test?






43. What part of the heart forms x Left border?






44. Based on the following information - is the renal transplantation rejection acute - chronic - or hyperacute? - Weeks to months after transplantation; abrupt onset of oliguria and azotemia; seen as neutrophilic vasculitis and interstitial lymphocytes






45. Name the laryngeal muscle described by the following: x Only muscle to abduct the vocal cords






46. What is the most common opportunistic infection of the CNS in HIV?






47. What area of the GI tract has the highest activity of brush border enzymes?






48. What Brodmann area is associated with x Primary auditory cortex?






49. What cell of the male reproductive system produces testosterone?






50. Shuffling gait - cogwheel rigidity - masklike facies - pill - rolling tremor - and bradykinesia describe what form of dementia?

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