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USMLE Step 1 Prep

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What pneumoconiosis is associated with exposure to the following occupations or materials? - Shipyards - brake linings - insulation - and old building construction






2. What is the first membrane - bound Ig on B cell membranes?






3. What disease is a cavitation of the spinal cord causing bilateral loss of pain and temperature at the level of the lesion?






4. What pancreatic islet cell tumor is associated with hypoglycemia - sweating - hunger - confusion - and increased C- peptide levels?






5. What thyroid abnormality has the following? - TRH decreased - TSH decreased - T4 increased






6. Is bone deposition or resorption due to increased interstitial Ca2+concentrations?






7. What are the four major functions of the acquired immune system?






8. What class of drugs is used in the treatment of demineralization of the bone?






9. What is the primary method of nonverbal communication of emotional states?






10. What is the most common one? - Liver tumor






11. What hormone is required for 1 - 25- dihydroxy- vitamin D (1 - 25- diOH- D) to have bone resorbing effects?






12. What chromosome 4 - AD disorder is a degeneration of GABA neurons in the striatum of the indirect pathway of the basal ganglia?

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13. Name the T- cell CD marker: Is a costimulatory molecule in T cell activation






14. What organelles make ATP - have their own dsDNA - and can synthesize protein?






15. In what pathway of the basal ganglia do lesions result in an underactive cortex with hypokinetic - slow - or absent spontaneous movement?

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16. What Freudian psyche component is described as x Reality - rationality - language basis?






17. What restriction endonuclease site is destroyed in sickle Beta- globin allele?






18. What is the best measure of total body vitamin D if you suspect a deficiency?






19. What type of correlation is defined as x Two variables with no linear relation to one another?






20. What antiviral agent is used to treat RSV - influenza A and B - Lassa fever - and hantavirus and as an adjunct to IFN- in hepatitis C?






21. Name the most common type or cause - Sudden cardiac death






22. Projectile nonbilious vomiting and a small knot at the right costal margin (olive sign) are hallmarks of What embryonic disorder?






23. What syndrome is characterized by embryologic failure of the third and fourth pharyngeal pouches resulting in hypocalcemia - tetany - and T- cell deficiency?






24. What enzyme does HIV use to integrate the proviral dsDNA into the host?






25. What enzyme catalyzes the rate - limiting step in cholesterol metabolism?






26. What is the term of the viral growth period when no viruses can be found intracellularly?






27. What type of error is made if you accept the null hypothesis when it is false?

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28. Name the associated chromosome - Neurofibromatosis type 1






29. Name these narcissistic defense mechanisms: x Everything in the world is perceived as either good or bad . No middle ground; it is all extremes.






30. What hormone disorder is characterized by the following abnormalities in sex steroids? - LH? - and FSH?? - Sex steroids - LH - FSH






31. What family do the following viruses belong to? - RSV






32. Name the associated chromosome - Edward syndrome






33. Which two tetracyclines have the highest plasma binding?






34. In What area of the GI tract are water - soluble vitamins absorbed?






35. What thyroid abnormality has the following? - TRH decreased - TSH decreased - T4 increased






36. What oxygen - dependent killing enzyme requires hydrogen peroxide and halide (Cl -) to produce hypochlorous acid?






37. What type of cerebral bleed is due to a rupture of a berry aneurysm in the circle of Willis?






38. Which hepatitis virus is in the Flaviviridae family?






39. What AA is substituted for glutamic acid at position 6 on the Beta - chain in patients with sickle cell anemia?






40. What type of lysosome is formed when lysosome fuses with a substrate for breakdown?






41. What disease caused by decompression sickness leads to multiple foci of ischemic necrosis that affect the head of the femur - humerus - and tibia?






42. What are the CAGE questions?






43. Name the MCC of death - In diabetic individuals






44. What CNS developmental abnormality is associated with 90% of syringomyelia?






45. Name the hormone






46. Does the left or right vagus nerve innervate the SA node?






47. What is the site of action for carbonic anhydrase inhibitors?






48. What is the MCC of the following meningitides? - In neonates to 3 months of age






49. Protein production - bile secretion - detoxification - conjugation - and lipid storage.






50. What component of the ETC is inhibited by the following? - Atractyloside







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