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USMLE Step 1 Prep

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. The most frequent number occurring in a population is what?






2. Councilman bodies






3. Name the most common type or cause - Nephritic syndrome in adults






4. In the window phase of a hepatitis B infection - which Abs do you see?






5. During What embryonic week do somites begin to form?






6. After traveling in a plane across the Atlantic Ocean - an obese male goes to the ER with swollen right leg and sudden onset of shortness of breath. What do you immediately diagnose?






7. Name the aphasia based on these characteristics: x Both Broca's and Wernicke's areas damaged by lesion in the presylvian speech area; trouble repeating statements; poor comprehension with telegraphic speech






8. What is the only enzyme in the body that uses N-5- methyl folate?






9. What enzyme - induced by insulin and activated by apo C- II - is required for chylomicron and VLDL metabolism?






10. The dose of which second - generation sulfonylurea agent must be decreased for patients with hepatic dysfunction?

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11. What is the most common lethal AR disorder affecting white Americans?






12. What enzyme is blocked by hydroxyurea?






13. What phase of the cell cycle are the following antineoplastic agents specific for? - Cytarabine






14. What mineral is an important component of the enzyme xanthine oxidase?






15. What virus lies dormant in the x Trigeminal ganglia?






16. What muscle of the middle ear is innervated by the mandibular division of CN V?






17. What is the most likely organism causing cellulitis in a patient who was cut by an oyster shell?






18. What phase of the cell cycle are the following antineoplastic agents specific for? - Cisplatin






19. Which cerebral herniation results in compression of the anterior cerebral artery?






20. What pancreatic islet cell tumor is associated with MEN I syndrome?






21. Indicates the patient has active pulmonary disease.






22. What endogenous pigment found in the substantia nigra and melanocytes is formed by the oxidation of tyrosine to dihydroxyphenylalanine?






23. What is the most common one? - Benign lesion that affects the breast






24. A 30-year - old woman goes to your office with bilateral multiple breast nodules that vary with menstruation and have cyclical pain and engorgement. What is your diagnosis?






25. What are the three main components of amyloid?






26. How many hydrogen bonds link A- T? C- G?






27. What happens to intrapleural pressure when the diaphragm is ontracted during inspiration?






28. Is CO2 a perfusion - or diffusion - limited O2 gas?






29. Mandibular hypoplasia - down - slanted palpebral fissures - colobomas - malformed ears - and zygomatic hypoplasia are commonly seen In what pharyngeal arch 1 abnormality?






30. How many ATPs per glucose are produced by pyruvate dehydrogenase?






31. Results in vitamin B12 malabsorption.






32. What form of depression is due to abnormal metabolism of melatonin?






33. Insulin - induced hypoglycemia is the most reliable (by far not the safest) test For what hormone deficiency?






34. What is the effect of T3 on the glucose absorption in the small intestine?






35. What AR syndrome is due to a deficiency of glycoprotein Ib - resulting in a defect in platelet adhesion?






36. What type of fiber or fibers are carried in (answer motor - sensory - or both) x Dorsal root?






37. What disease has a genetically low level of UDPglucuronate transferase - resulting in elevated free unconjugated bilirubin?

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38. What primary acid - base disturbance is cause by a decrease in alveolar ventilation (increasing CO2 levels) resulting in the reaction shifting to the right and increasing H+ and HCO3- levels?






39. What happens to intracellular volume when there is an increase in osmolarity?






40. What component of the ETC is inhibited by the following? - Cyanide






41. In a topographical arrangement of the cerebellar homunculus map - What area or lobe x Is involved in motor planning?






42. What drug that penetrates the blood - brain barrier is found in asthma preparations and used as a nasal decongestant?






43. Megaloblastic anemia and thrombocytopenia are signs of what vitamin deficiency?






44. If no fertilization occurs - How many days after ovulation does the corpus luteum begin to degenerate?






45. What form of antimicrobial therapy is best for an immunocompromised patient?






46. What direction does the primitive gut rotate? What is its axis of rotation?






47. What Ig activates the complement cascade most efficiently?






48. What parasite found in raw fish can produce vitamin B12 deficiency?






49. Where does the parotid (Stensen's) duct enter the oral cavity?






50. Have catalase.