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USMLE Step 1 Prep

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What is the drug of choice for treating ADHD?






2. What is the size of a positive PPD test for the following? (Reactive) x IV drug abuser






3. What thyroid abnormality has the following? - TRH decreased - TSH decreased - T4 decreased






4. A 60-year - old man has back pain (compression spinal fracture) - hypercalcemia - increased serum protein - Bence - Jones proteinuria - and monoclonal M- spike on serum electrophoresis. What is your diagnosis?






5. What glycoprotein in the HIV virus is used for fusion?






6. Name the antimicrobial agent whose major side effect is listed - Cartilage abnormalities






7. What mineral is required for cross - linking of collagen molecules into fibrils?






8. What does a loss of afferent activity from the carotid sinus onto the medulla signal?






9. What is the most serious form of tinea capitis - which results in permanent hair loss and is highly contagious?






10. Is the bound form or free form of a lipid - soluble hormone responsible for the negative feedback activity?






11. Which of the following






12. What phase of the female reproductive cycle is 14 days long?






13. What is the term for thickened - hyperpigmented skin in the axillae - groin - and skin folds associated with malignancies - obesity - and DM?






14. Based on the following information - is the renal transplantation rejection acute - chronic - or hyperacute? - Weeks to months after transplantation; abrupt onset of oliguria and azotemia; seen as neutrophilic vasculitis and interstitial lymphocytes






15. What germ cell tumor is seen in the 15- to 35-year - old age group - peaks when the person is 35 years of age - and is a bulky mass that spreads via the lymphatic system?






16. Name the primary vesicle the following structures are derived from (proencephalon - mesencephalon - or rhombencephalon) - Midbrain






17. What are the three left - to - right shunts?






18. What is the main factor determining GFR?






19. What are the two most important features in the diagnosis of malaria?






20. What is the most common one? - Intraspinal tumor






21. What is the name of the force that develops in the wall of the lungs as they expand?






22. Which centrally acting a2- adrenergic agonist is used in the treatment protocol of opioid withdrawal?






23. What prevents the down - regulation of the receptors on the gonadotrophs of the anterior pituitary gland?






24. Describe the organism based on the following information: x Beta - hemolytic Streptococcus sensitive to bacitracin






25. Name the type of regeneration (i.e. - labile - stable - or permanent) based on the following examples - Epidermis






26. What drug is being given to HIV- positive mothers during labor and to the children after birth to decrease the risk of mother - to - child HIV transmission?






27. When is the first arrested stage of development in the female reproductive cycle?






28. What disorder is due to a 5-- reductase deficiency - resulting in testicular tissue and stunted male external genitalia?






29. What is the label given to an individual whose IQ is x 120 to 129






30. An 80-year - old woman presents to you with right - sided temporal headache - facial pain and blurred vision on the affected side - and an elevated ESR. Your diagnosis?






31. What component of an ECG is associated with the following? - Ventricular depolarization






32. What is the term for production of a DNA copy from an RNA molecule?






33. What leukemia is characterized by Philadelphia chromosomal translocation (9;22); massive splenomegaly; peripheral leukocytosis (commonly > 100 - 00); decreased LAP levels; and nonspecific symptoms of fatigue - malaise - weight loss - and anorexia?






34. Metformin is contraindicated in ________ because of weight gain as its side effect.






35. ______________ that slow bacterial growth are bactericidal.






36. What condition results in the following CSF results? - Opening pressure 250 mm H2O; WBCs 250 (90% lymphocytes); glucose 35; protein 100






37. In what X- linked recessive disease is there a decrease in the HMP shunt - along with Heinz body formation?






38. What are the two ways to leave the prevalence pot?






39. What disease is a cavitation of the spinal cord causing bilateral loss of pain and temperature at the level of the lesion?






40. What are the most common causes of osteomyelitis x In patients with sickle cell disease?






41. Are the following parameters associated with an obstructive or restrictive lung disorder: decreased FEV1 - FVC - peak flow - and FEV1/FVC; increased TLC - FRC - and RV?






42. What statistical test checks to see whether the groups are different by comparing the means of two groups from a single nominal variable?






43. Name the most common type or cause - Cyanotic heart disease






44. Ensures emancipation.






45. What platelet disorder is characteristically seen in children following a bout of gastroenteritis with bloody diarrhea?






46. Name the stages of sleep with these EEG patterns: x Sawtooth waves - random low voltage pattern






47. What vitamin is a component of the enzymes fatty acid synthase and acyl CoA?






48. What percentage of nephrons is cortical?






49. What enzyme is deficient in hereditary protoporphyria?






50. What enzyme is deficient in selective T cell immunodeficiency?