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Test your basic knowledge |
USMLE Step 1 Prep
Start Test
Study First
Subjects
:
health-sciences
,
usmle-step-1
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What is the most common causative organism of acne vulgaris?
Carbonic anhydrase inhibitors (acetazolamide and dorzolamide)
Blastoconidia
Propionibacterium acnes
Absolutely not. Diabetics who are given a Beta- blocker for an acute chest syndrome have significantly better outcomes than those who do not.
2. Name the antimicrobial agent whose major side effect is listed - Teratogenicity
VPL nucleus sends its fibers to synapse in the postcentral gyrus of the parietal lobe.
Metronidazole
Varicella
Nimodipine
3. What prokaryotic positioning enzyme in translation is blocked by the following? - Tetracycline
EF- Tu and EF- Ts of the 30S ribosomal subunit
Constipation and miosis
Hemochromatosis
Yohimbine
4. What artery travels with the following veins? - Middle cardiac vein
GABA - quantitatively
Lithium
Circumvallate papillae
Posterior interventricular artery
5. What are the three Bs of adult polycystic kidneys?
1. Big 2. Bilateral 3. Berry aneurysm
Capillary flow and pressure increase with arteriolar dilation and decrease with arteriolar constriction.
Zinc (Zn) deficiency
The CD4 T cell; the APC is the first cell in the immune response.
6. Name the cancer associated with the following oncogenes. (Some may have more than one answer) x Ki - ras and erb -2
Lung cancer
VLDLs
epithelial lining
18 years old (except if emancipated)
7. Name the cancer associated with the following tumor markers. (Some may have more than one answer.) x alpha - Fetoprotein
Lipoxygenase pathway - from arachidonic acid
Deferoxamine - penicillamine
Glioblastoma multiforme
Hepatoma and nonseminomatous testicular germ cell tumors
8. What form of hormone is described as having membrane - bound receptors that are stored in vesicles - using second messengers - and having its activity determined by free hormone levels.
Homeodomain proteins
Water - soluble hormones are considered fast - acting hormones.
Arterioles have the largest drop - whereas the vena cava has the smallest pressure drop in systemic circulation.
>10 mm
9. What is the most common one? - Form of muscular dystrophy
Duchenne muscular dystrophy
Ptosis (eyelid drooping) - miosis (pupillary constriction) - and anhydrosis (lack of sweating) occur when the preganglionic sympathetic fibers from T1- to T4 are obstructed.
Middle meningeal artery
Hepatocellular carcinoma
10. Reed - Sternberg cells
Hodgkin lymphoma
Massive influx of calcium
Pedophilia
Submandibular gland produces mainly serous and the sublingual gland produces mainly mucous secretions.
11. Leading to gallstones and steatorrhea.
Allograft
TLC - FRC - and RV have to be calculated. (Remember - any volume that has RV as a component has be calculated.)
NH4+(ammonium)
Pancreatic delta - cell tumors inhibit CCK secretion
12. What AA is substituted for glutamic acid at position 6 on the Beta - chain in patients with sickle cell anemia?
Nephrotoxic oxylate stones
Valine
Metabolic acidosis (summary: low pH - high H+ - and low HCO3-)
Altruism
13. What two PGs are used to induce labor?
Specificity (it deals with the healthy)
Scavenger receptor (SR- B1)
Iron deficiency anemia
PGE2 and PGF2a
14. What determines the rate of a reaction?
Afferent arteriole
The energy of activation (Ea)
Meiosis I; disjunction with centromere splitting occurs during meiosis II.
Pneumocystis carinii
15. Name the RNA subtype based on the following: x RNA molecules with enzymatic activity
Vibrio parahaemolyticus
TCA cycle.
AML- M3
Ribozymes
16. Name the cluster B personality disorder: x In a constant state of crisis - promiscuous - unable to tolerate anxiety- causing situations - afraid of being alone - and having intense but brief relationships
Peutz - Jeghers syndrome
Left ventricle and auricle of left atrium
Borderline
Conduction aphasia
17. Which four bacteria require cysteine for growth?
IDL
Serratia
Pasteurella - Brucella - Legionella - and Francisella (all of the - ellas)
Subacute combined degeneration - Which is bilateral below the level of the lesion.
18. What is the most common one? - Location of ependymomas in children
Edinger - Westphal nucleus (via CN III)
In children - the fourth ventricle; in adults - the lateral ventricle or spinal cord
Calcium oxylate
Marrow failure - cancer - and leukemia
19. What is the term for days 15 to 28 in the female cycle?
Luteal phase
Risperidone
Osteomalacia. Osteoporosis has normal levels of calcium - phosphorus - and alkaline phosphatase.
Median nerve
20. What is the DOC for esophageal candidiasis?
Fluconazole
Stable
Minoxidil (orally and topically - respectively!)
With opioid use the pupils become pinpoint (miosis) because of increased cholinergic activity.
21. What three drugs are associated with SLE- like syndrome in slow acetylators?
GABA - quantitatively
Cohort studies determine incidence and causality - not prevalence.
Hydralazine - isoniazid - and procainamide (HIP)
Ulnar and radial arteries (ulnar is the main supplier)
22. Require NaCl in its growth medium.
Libman - Sacks endocarditis
Five pairs through five lumbar vertebrae. Totaling 31 pairs of spinal nerves.
The popliteal artery - the deepest structure in the popliteal fossa - risks injury in a supracondylar fracture of the femur.
Vibrio parahaemolyticus
23. Cri - du - chat syndrome results in a terminal deletion of the short arm of what chromosome?
LDL
When the pH is more acidic than the pI - it has a net positive charge - and when the pH is more basic than the pI - it has a net negative charge.
DNA polymerase -?
Chromosome 5
24. What is the term for a congenital absence of the ganglionic cells of the Auerbach and Meissner plexus in the rectum and sigmoid colon?
Ribavirin
Coagulative necrosis
Hirschsprung disease (aganglionic megacolon)
MEN IIa (or Sipple syndrome)
25. What is the name of the B cell that secretes Ig?
Maxillary artery
Chromosome 11p
Elevated ASO titers and serum complement levels
Plasma cell (mature B lymphocyte)
26. What wave is the cause of the following venous pulse deflections? - The contraction of the right atrium
Lipoprotein lipase
wave
S phase
Rhabdovirus
27. What female follicular cell is under LH stimulation and produces androgens from cholesterol?
Theca cell
Conduction aphasia
The Halsted - Reitan battery. It consists of finger oscillation - speech sound perception - rhythm - tactual - and category testing.
Cyanide
28. What is the term to describe a decrease in the cell size and function usually associated with disuse?
Emphysema
Pneumotaxic center (short - fast breaths)
Atrophy. Disuse can also be due to immobilization - ischemia - aging - and a host of other causes.
Salmonella typhi
29. Name the lung measurement based on the following descriptions: x The maximal volume inspired from FRC
Inspiratory capacity
Trimethoprim/sulfamethoxazole (TMP- SMX)
Alanine cycle
Protamine sulfate
30. In what disease do you see horseshoe kidneys - rockerbottom feet - low - set ears - micrognathia - and mental retardation?
Edward syndrome (trisomy 18)
Alzheimer disease
Aldehyde dehydrogenase
CD4+T cells
31. Name the lipoprotein based on the following characteristics - apo E - apo C- II - apoB-48
Lymph nodes
Both Neisseria and Moraxella are gram - negative cocci.
Chylomicrons
Puborectalis
32. What diseases are associated with the HLA- DR3 allele
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33. Name the primary vesicle the following structures are derived from (proencephalon - mesencephalon - or rhombencephalon) - Cerebral hemispheres
Proencephalon
Thiogalactoside transacetylase
Thyroid hormones
Achalasia
34. Name the aphasia based on these characteristics: x Both Broca's and Wernicke's areas damaged by lesion in the presylvian speech area; trouble repeating statements; poor comprehension with telegraphic speech
Arch of the aorta
Imipenem and meropenem
Global aphasia
Leiomyoma
35. What would be the result if an Ab were cleaved with pepsin?
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36. What aneurysm of the circle of Willis is associated with polycystic kidney disease?
Temporal arteritis (giant cell arteritis)
produce bile
Berry aneurysm
Paneth cells
37. What structure of the knee is described thus? - Prevents adduction
CN VII
Healing by secondary intention
Male pseudo - intersexuality (hermaphrodite); these individuals are 46XY.
Lateral collateral ligament
38. Which benzodiazepine has the longest half - life?
In the dorsal horn of the spinal cord on the primary afferent neurons
Melatonin - serotonin - and CCK
NaCl is removed from the lumen to dilute the fluid leaving the loop of Henle.
Flurazepam
39. Name the most common type or cause - Nephrotic syndrome
Membranoproliferative glomerulonephritis (MGN)
CN VII
Glyceraldehyde dehydrogenase
Syphilitic
40. In a diabetic patient - to What does aldose reductase convert glucose?
Roth spots - and they are seen in bacterial endocarditis.
M12 strains
Sorbitol (resulting in cataracts)
1. Lateral pectoral 2. Lateral head of the median 3. Musculocutaneus
41. What is the label given to an individual whose IQ is x 130
Xanthine oxidase
CN VII and VIII
Very superior (<2.5% of the population)
Paget disease (osteitis deformans)
42. What papillae send their senses via chorda tympani of CN VII?
Denial Anger Bargaining Depression Acceptance No - they can be skipped - repeated - and completed out of sequence.
alpha - Cells; glucagon has stimulatory effects on - cells and inhibitory effects on - cells.
Yolk sac tumor
Fungiform papillae
43. Can parents withhold treatment from their children?
2 ATPs by oxidative phosphorylation
Yes - as long the illness does not threaten limb or life. If illness is critical or an emergency - treat the child.
LDL
Glutamate dehydrogenase
44. Name the antimicrobial agent whose major side effect is listed - CN VIII damage (vestibulotoxic)
Amantadine
Aminoglycosides
External 3' - 5' PDE bonds
Metastatic carcinomas
45. What pancreatic islet cell tumor is associated with watery diarrhea - hypokalemia - and achlorhydria?
VIPoma
hCG can be detected in the blood by day 8 and in the urine by day 10.
Operon
Infliximab
46. ADH is secreted in response to What two stimuli?
Dopamine antagonists
ADH is secreted in response to increased plasma osmolarity and decreased blood volume.
Transcription (C comes before L in the alphabet - and transCription comes before transLation)
A left CN X lesion results in the uvula deviating to the right. (Uvula points away from the affected side.)
47. What cancer of the male genitourinary system is associated with osteoblastic bony metastasis?
Dysplasia
Prostatic carcinoma
Superior gluteal nerve
Streptomycin
48. Are the following responses associated with histamines H1 or H2 receptor activation? - Inotropic action and automaticity
H 2
Adenovirus
Gain of hypertonic fluid (mannitol or hypertonic saline)
Labile
49. What water - soluble - vitamin deficiency is associated with neural tube defects in the fetus?
Labetalol
ICF volume decreases when there is an increase in osmolarity and vice versa.
5 years old
Folic acid
50. What are the following changes seen in the luminal fluid by the time it leaves the PCT of the nephron? - Percentage of Na+ - Cl - - K+ left in the lumen
t the end of the PCT 25% of Na+ - Cl - - K+ is left
Rabies
Splitting of the first heart sound occurs during inspiration because of the increased output of the right ventricle - delaying the closure of the pulmonic valve.
Hypnopompic hallucinations occur during awakening - whereas hypnagogic hallucinations occur while one is falling asleep.