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USMLE Step 1 Prep

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What is the term for days 1 to 7 of the female cycle?






2. What are the three reasons for the effectiveness of the blood - brain barrier?






3. What are the growth factors released from the liver called?






4. What syndrome is due to a deficiency of surfactant?






5. What stromal tumor in males is characterized histologically with crystalloids of Reinke?






6. What is the renal compensation mechanism for alkalosis?






7. What hormone is characterized by the following renal effects? - Calcium reabsorption - phosphate excretion






8. What stage of male development is characterized by the following LH and testosterone levels? - LH pulsatile amplitude and levels increase - with increased testosterone production.






9. Describe What type of fluid is either gained or lost with the following changes in body hydration for the ECF volume - ICF volume - and body osmolarity - respectively: x ECF: increase; ICF: no change; body: no change






10. Which direction is air flowing when the intra - alveolar pressure is zero?






11. What prion - associated CNS pathology produces rapidly progressive dementia with myoclonus - involuntary movements - and death within 6 to 12 months?






12. Name the most common type or cause - Breast lump in females






13. What diseases are associated with the HLA- B27 allele

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14. Name the DNA virus: x Circular dsDNA; naked; icosahedral; replicates in the nucleus






15. What apoprotein on HDL activates lecithin - cholesterol acyltransferase (LCAT)?






16. What AA undergoes N- glycosylation?






17. Name the type of necrosis - Due to lipase activity and has a chalky white appearance






18. What type of muscle is characterized by no myoglobin - anaerobic glycolysis - high ATPase activity - and large muscle mass?






19. What endocrine abnormality is characterized by the following changes in PTH - Ca2+ - and inorganic phosphate (Pi)? - PTH increased - Ca2+ decreased - Pi decreased






20. What is the most common chromosomal abnormality associated with CLL?






21. Can incidence - prevalence - and cause and effect be assessed in x Cross - sectional studies?






22. Where is tropocollagen aggregated to form a collagen fibril?






23. What substance is used to test platelets' response in patients with von Willebrand disease?






24. What are the three components to the asthma triad?






25. What is the term for an increase in the number of cells in a tissue?






26. What is the most common one? - Sites for abdominal aorta aneurysm






27. Which class of antiarrhythmics are calcium channel blockers?






28. What is the term for a deficiency or absence of sexual fantasies or desires?






29. What seronegative spondyloarthropathy is seen in HLA- B27- positive young females and presents with the triad of conjunctivitis - urethritis - and arthritis affecting the knees and ankles?






30. What is the only Rickettsia that is stable in the environment?






31. What is characterized by an intense inflammatory reaction - an increase in the amounts of granulation tissue and wound contraction by myofibroblasts?






32. What glycoprotein allows platelets to adhere to each other through the use of fibrinogen?






33. What receptor is in the smooth muscle cells of the small bronchi - is stimulated during inflation - and inhibits inspiration?






34. How many codons code for AAs? How many for termination of translation?






35. Is a brush border enzyme.






36. What is the only specific Ag - presenting cell?






37. Which cestode infection results in alveolar hydatid cyst disease?






38. What type of hernia is described as passing through the deep lateral ring of the inguinal canal?

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39. What are the two broad - spectrum penicillins?






40. Both submandibular and sublingual glands are innervated by CN VII (facial) and produce mucous and serous secretions. Which one mainly produces serous secretions?






41. What are the adult remnants of the following structures? - Ductus arteriosus






42. What is used as an index of the number of functioning carriers for a substance in active reabsorption in the kidney?






43. What enzyme is deficient in congenital erythropoietic porphyria?






44. What enzyme catalyzes the rate - limiting step of the urea cycle?






45. What two Beta- blockers decrease serum lipids?






46. What vessels carry deoxygenated blood into the lungs from the right ventricle?






47. What condition results in the following CSF results? - Opening pressure 450 mm H2O; 5 WBCs (90% lymphocytes); normal glucose and protein levels






48. What coronary artery vasculitis is seen in Japanese infants and children less than 4 years old with acute febrile illness - conjunctivitis - maculopapular rash - and lymphadenopathy?






49. What are the two MCC of acute epididymitis in males? - Less than 35 years old






50. Based on the following information - is the renal transplantation rejection acute - chronic - or hyperacute? - Months to years after transplantation; gradual onset of HTN - oliguria - and azotemia; seen as intimal fibrosis of the blood vessels and in