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USMLE Step 1 Prep

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What three organs are necessary for the production of vitamin D3(cholecalciferol)?






2. Name the cancer associated with the following chemical agents. (Some may have more than one answer.) x Naphthylamine






3. Which encapsulated fungus is found in soil enriched with pigeon droppings?






4. Name the product or products of arachidonic acid: x Vasodilation






5. What skin condition is a localized proliferation of melanocytes presenting as small - oval - light brown macules?






6. What nonmotile gram - negative - non - lactose - fermenting facultative anaerobic rod uses the human colon as its only reservoir and is transmitted by fecal - oral spread?






7. Name the muscle type based on these descriptions: x Involuntary contraction - uninuclear nonstriated fibers - actin and myosin not forming banding pattern; lack of T tubules - gap junctions - and calmodulin.






8. What mushroom poisoning is associated with fulminant hepatitis with extensive liver necrosis?






9. Name the type of mutation: x New codon specifies for a stop codon






10. Which immunoglobulin is secreted by the plasma cells in the gastrointestinal tract?






11. What is the term for having fantasies or dressing in female clothes for sexual arousal by heterosexual men?






12. Metformin is contraindicated in ________ because of weight gain as its side effect.






13. What three organs are responsible for peripheral conversion of T4 to T3?

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14. What pancreatic islet cell secretes somatostatin?






15. What is the main mechanism for exchange of nutrients and gases across a capillary membrane?






16. Name the cancer associated with the following chemical agents. (Some may have more than one answer.) x Vinyl chloride






17. What enzyme is deficient in alkaptonuria?






18. Kaiser - Fleischer rings - abnormal copper metabolism - and ceruloplasmin deficiency characterize what disease - which may include symptoms of dementia when severe?

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19. Name the most common type or cause - Meningitis in renal transplantation patients






20. What lymphoma is associated with bleeding and cryoglobulin precipitation at low temperatures - headache and confusion due to hyperviscosity - IgM M- protein spike on serum electrophoresis - and Russell bodies?






21. What are the adult remnants of the following structures? - Ductus arteriosus






22. What medication is used to help alcoholics avoid relapse by decreasing glutamate receptor activity?






23. What molecule that is needed to trigger T cell activation is noncovalently linked to TCR?






24. Does Cushing syndrome or Cushing disease have elevated ACTH levels and cortisol suppression with dexamethasone?

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25. What bacterium found in poorly preserved canned food causes flaccid paralysis?






26. There is an inverse relationship between fat content and...






27. What segments of the lumbosacral plexus form the following nerves? - Femoral nerve






28. Name the most common type or cause - Lung abscess






29. What is the term to describe the soft - flabby feel and diminished reflexes seen in patients with acute cerebellar injury to the deep cerebellar nuclei?






30. What syndrome that is due to an adrenal gland adenoma produces excess aldosterone resulting in HTN - hypokalemia - and low rennin levels?






31. What three circumstances allow a child to be committed to institutional care?

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32. What is the most common one? - Malignant carcinoma of the ovaries






33. What are the glycoprotein receptors that platelets and fibrinogen cross - link to when forming a thrombus?






34. In the systemic circulation - what blood vessels have the largest pressure drop? Smallest pressure drop?






35. What linkage of complex CHOs does pancreatic amylase hydrolyze? What three complexes are formed?






36. Name the four components of the narcoleptic tetrad.






37. What malignant tumor of the skin is associated with Birbeck granules?






38. If the radius of a vessel is decreased by half - what happens to the resistance?






39. What enzyme is deficient in the following glycogen storage disease? - McArdle's disease






40. What is the best measure of total body vitamin D if you suspect a deficiency?






41. What two arteries join to form the superficial and deep palmar arches of the hand?






42. What three cephalosporins inhibit vitamin K- dependent factors?






43. What condition results in the following CSF results? - Opening pressure 400 mm H2O; WBCs 8500 (90% PMNs); glucose 15; protein 120






44. Can an acute MI be diagnosed only by looking at an ECG?






45. What enzyme is inhibited by propylthiouracil (PTU)?

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46. What general pattern of sleep is described by slowing of EEG rhythms (high voltage and slower synchronization) - muscle contractions - and lack of eye movement or mental activity?






47. In what compartment of the thigh is the profundus femoris artery found?

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48. What are the three carboxylase enzymes that require biotin?






49. What is the term for a large - immature RBC that is spherical - blue - and without a nucleus?






50. What type II hypersensitivity disorder is defined as x Autoantibodies directed against ACh receptors?