Test your basic knowledge |

USMLE Step 1 Prep

Subjects : health-sciences, usmle-step-1

Instructions:

Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can study here.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Where is the action potential generated on a neuron?
Peyer's patch
Superior
Validity (remember - reliability is necessary but not the only thing needed for validity)
Axon hillock

2. Name the type of necrosis - Seen as dead tissue with liquefactive necrosis?
CN III - IV - and VI
HHV 8
Granulosa cell
Liquefaction necrosis

3. What result occurs because of the negative alveolar pressure generated during inspiration?
Alzheimer disease
Air flows into the respiratory system.
Superior colliculus (Remember S for Superior and Sight). The inferior colliculus processes auditory information from both ears.
Acute tubular necrosis

4. In what X- linked recessive disease is there a decrease in the HMP shunt - along with Heinz body formation?
Tetanospasmin (also called tetanus toxin)
Vital capacity (VC)
Parkinson's disease
G-6- PD deficiency

5. What gluconeogenic mitochondrial enzyme requires biotin?
CN IX
Pyruvate carboxylase
1. Notify police. 2. Try to detain the person making the threat. 3. Notify the threatened victim.
At least 5 lobes

6. Are used in the management of an acute asthmatic attack.
HBcAb IgG and HBsAb IgG
Oxytocin
Beta2- Adrenergic agents
1. Cefamandole 2. Cefoperazone 3. Moxalactam

7. What neurotransmitter is associated with sedation and weight gain?
Microcytotoxic assay
Histamine
Xanthine oxidase
IDL

8. What is the only important physiological signal regulating the release of PTH?
CN III
Low interstitial free Ca2+ concentrations
HBeAb
MI

9. What are the four ways to increase TPR?
1. Decrease the radius of the vessel 2. Increase the length of the vessel 3. Increase the viscosity 4. Decrease the number of parallel channels
Fossa ovale
Adhesions and hernias
Pygmalion effect (experimenter expectancy). This can be eliminated with double - blind studies.

10. What are the primary neurotransmitters at the following sites? - Brainstem cells
Transtentorial (uncal)
ll
Serotonin
Lateral compartment of the leg - superficial peroneal nerve

11. What determines the Vmax of skeletal muscle?

Warning: Invalid argument supplied for foreach() in /var/www/html/basicversity.com/show_quiz.php on line 183

12. Name the T- cell CD marker: x Essential for Ab isotype switching (for B cell binding)
CD40 ligand
Acarbose
Niacin (B3)
It repeats every 90 to 120 minutes and correlates with elevated levels of motilin.

13. What type of erythema do you see in x Rheumatic fever?
Erythema marginatum
Parvovirus (it is the only ssDNA virus)
Alcoholism
Class II

14. What area of the limbic system is responsible for attaching emotional significance to a stimulus?
Amygdala; it helps imprint an emotional response in memory.
5 years old
1. IgA receptor 2. Transport of IgA across epithelial barriers 3. Protection of IgA from degradative proteases
70S ribosomes in prokaryotes and 80S ribosomes in eukaryotes

15. Name the hormone
T3
Glucagon
The Fc region of IgG and C3b
Y - W-135 - and C and A capsular polysaccharides

16. What is the most common one? - Thyroid adenoma
Follicular adenoma
Staphylococcus aureus
Patau syndrome (trisomy 13)
Dilation of efferent arteriole

17. What cytokines do Th2 cells secrete to inhibit Th1 cell function?
Pasteurella multocida
If the polyuria begins before the collecting ducts - the patient is dehydrated and electrolyte depleted. If the polyuria originates from the collecting ducts - the patient is dehydrated with normal electrolytes.
50%. The uncles and older siblings are the most likely perpetrators - although stepfathers also have a high rate.
IL-4 - IL-10 - and IL-13

18. What region of the Ig does not change with class switching?
Nephrotoxic oxylate stones
Sinus venosus
Hypervariable region
1. Iliocostalis 2. Longissimus 3. Spinalis ('I Love Science' muscles)

19. What viral infection in patients with sickle cell anemia results in aplastic crisis?
Propionibacterium acnes
Recovery and death
Parvovirus B 19
prognostic predictors

20. Is the bound form or free form of a lipid - soluble hormone responsible for the negative feedback activity?
VLDLs
Quaternary structure
Minimal change disease
Free form determines hormone activity and is responsible for the negative feedback loop.

21. Paranoid and catatonic schizophrenia are good...
prognostic predictors
Ependymal cells
Phenylalanine hydroxylase
Efficacy

22. What primary acid - base disturbance is caused by an increase in alveolar ventilation (decreasing CO2 levels) resulting in the reaction shifting to the left and decreasing both H+ and HCO3- levels?
Silent
Arterioles have the largest drop - whereas the vena cava has the smallest pressure drop in systemic circulation.
Autism. Head - banging - rocking - and self - injurious behaviors are also common in autism.
Respiratory alkalosis (summary: low CO2 - low H+ - slightly low HCO3-)

23. How are lipid solubility and potency related for inhaled anesthetics? How do they affect onset and recovery?
Granulosa cells
Pernicious anemia
Inhaled anesthetics with low lipid solubility have low potency (directly related) - so they have rapid induction and rapid recovery; vice versa for drugs with high lipid solubility.
2 ATPs by oxidative phosphorylation

24. Name the lipoprotein based on the following characteristics - apo E - apo C- II - apoB-48
Papillary carcinoma of the thyroid
Chylomicrons
Toxic dose for 50% of drug takers (median toxic dose)
Inspiratory reserve volume (IRV)

25. What is the most common one? - Viral cause of myocarditis
Anemia of chronic disease
LC4 - LD4 - and LE 4
Arnold - Chiari malformation type 2
Coxsackie B

26. What pancreatic islet cell secretes glucagons?
Proud flesh
Cancer
alpha - Cells; glucagon has stimulatory effects on - cells and inhibitory effects on - cells.
IgA

27. What determines the plasma level at steady state?
refuse
Graves disease
The rate of infusion
IgA - IgD - IgE - IgG - and IgM

28. Name these mature defense mechanisms: x Converting an unacceptable impulse to a socially acceptable form (Hint: it is the most mature of all defense mechanisms)
Median nerve
1. Skin color 2. Heart rate 3. Reflexes 4. Muscle tone 5. Respiratory rate APGAR - Appearance - Pulse - Grimace - Activity - Respiration
Rhombencephalon
Sublimation

29. What phase of Interphase is haploid (N)?
G1 phase; G2 and S phase are diploid (2N).
Bronchoconstriction is associated with parasympathetic stimulation (ACh) - and catecholamine stimulation is associated with bronchodilation (why epinephrine is used in emergency treatment of bronchial asthma.)
Autoimmune hemolytic anemia
Denial Anger Bargaining Depression Acceptance No - they can be skipped - repeated - and completed out of sequence.

30. What type of jaundice is seen in Rotor's syndrome?
Sucralfate
Conjugated (direct) hyperbilirubinemia
Translation
Factitious disorder

31. What are the four capsular polysaccharides used in the Neisseria meningitides vaccine?
Klinefelter syndrome
Y - W-135 - and C and A capsular polysaccharides
Menstruation
Terminal collecting duct has the highest concentration and Bowman's capsule has the lowest concentration of inulin.

32. What gluconeogenic enzyme is absent in muscle - accounting for its inability to use glycogen as a source for blood glucose?
Target cell
Obesity - DM - HTN - multiparity - early menarche - and late menopause
Chromosome 5 - 21
Glucose -6- phosphatase

33. Is jugular venous distention a presentation of isolated left or right heart failure?
Right - sided
HBcAb and HBeAb. You see the antibodies c and e.
Hemophilia A
Mesonephric duct

34. Does the direct or indirect basal ganglia pathway result in a decreased level of cortical excitation?
Motilin
Proximal to distal progression
Although both pathways are associated with disinhibition - the indirect basal ganglia pathway is associated with a decreased level of cortical excitation.
Iodine - resulting in congenital hypothyroidism

35. Senile plaques
1. Increased glucose uptake by fat cells 2. Increased triglyceride uptake by fat cells 3. Increased conversion of CHOs into fat 4. Decreased lipolysis in fat tissue 5. Decreased ketone body formation
Posterior cruciate ligament
Tensor tympani
Alzheimer disease

36. Name the type of regeneration (i.e. - labile - stable - or permanent) based on the following examples - Kidney
Stable
Palindrome
Cancer
Stereocilia

37. Where are the enzymes for the ETC and oxidative phosphorylation found?
With arteriolar constriction both the flow and pressure downstream decrease.
The inner membrane of the mitochondria (cristae)
Fourth M PITS for pharyngeal pouch derivatives
Inulin

38. What are the three branches of the inferior mesenteric artery?
Budd - Chiari syndrome
Mitral stenosis
Left colic - superior rectal - and sigmoidal arteries
Hepatitis B

39. What is the most common one? - Liver tumor
Stable
Metastatic carcinoma
150 mcg/day is the minimal daily intake needed. Most people ingest 500 mcg/day.
Spectinomycin

40. Name the stages of sleep with these EEG patterns: x Sawtooth waves - random low voltage pattern
REM
Reaction formation
Gilbert's syndrome
Musculocutaneous nerve

41. What condition results in the following CSF results? - Opening pressure 400 mm H2O; WBCs 8500 (90% PMNs); glucose 15; protein 120
Yes - as long the illness does not threaten limb or life. If illness is critical or an emergency - treat the child.
IgD; IgM is also correct.
Succinyl CoA
Bacterial meningitis

42. What is the term for the rate measured for a subgroup of a population?
Spleen
Specific rate (e.g. - men aged 55-60)
apo B-48
Dilation of efferent arteriole

43. What area of the brain acts as the center for contralateral horizontal gaze?
The biofeedback model is based on the parasympathetic nervous system.
Paranoid
Frontal eye field (Brodmann area 8)
Triazolam

44. In what rare lung malignancy have 90% of patients had an occupational exposure to asbestos?
EF- Tu or EF- ts and GTP
Malignant mesothelioma
Flucytosine
Intrapleural pressure at the base is -2.5 cm H2O (more positive than the mean) - resulting in a force to collapse the alveoli.

45. What syndrome that is due to an adrenal gland adenoma produces excess aldosterone resulting in HTN - hypokalemia - and low rennin levels?
Conn syndrome (primary hyperaldosteronism)
Empyema
HDL
Negative

46. Do the following structures pick up stain from hematoxylin or eosin? - Fibrin
T and B- cells belong to the adaptive branch - whereas PMNs - NK cells - eosinophils - macrophages - and monocytes belong to the innate branch.
Eosin
Neomycin
Central. Remember - there is a deficiency in ADH production in the central form.

47. What leukemia affects a 4-year - old child with 3 months of fever - fatigue - generalized lymphadenopathy - CNS involvement - hepatosplenomegaly - bleeding - and platelet count below 100 - 000?
RBCs. That is why it is called red pulp.
Saccule and utricle
The scaphoid is the most commonly fractured and the lunate is the most commonly dislocated.
ll

48. What class of heparin is active against factor Xa and has no effect on PT or PTT?
Increased GABA levels decrease the likelihood of learned helplessness.
Vagus nerve
Low molecular weight heparin (LMWH)
a - Methyldopa (Guanabenz or clonidine is also used.)

49. Risk factors for endometrial carcinoma.
Metabolic acidosis (summary: low pH - high H+ - and low HCO3-)
Negative reinforcement
Obesity - DM - HTN - multiparity - early menarche - and late menopause
Hairy cell leukemia

50. What AA is a precursor of the following substances? - NAD
Tryptophan
t the end of the PCT 25% of Na+ - Cl - - K+ is left
Surface tension; in the alveoli - it is a force that acts to collapse the lung.
Sleep latency