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USMLE Step 1 Prep

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Name the thalamic nucleus based on its input and output - Input from the trigeminal pathways; output to primary somatosensory cortex of the parietal lobe






2. What is the term to describe the increased rate of secretion of adrenal androgens at the onset of puberty?






3. Name the Hgb - O2 binding site based on the following information: x Remains attached under most physiologic conditions






4. What classical conditioning therapy or modification is described as x Triage of a hierarchy of fears (from least to most) - then teaching muscle relaxation techniques in the presence of those fears until the subject is not afraid anymore?






5. What thyroid abnormality has the following? - TRH increased - TSH increased - T4 decreased






6. What Beta2- agonist is used as a prophylactic agent in the treatment of asthma?






7. What skin carcinoma is a superficial dermal infiltrate of T lymphocytes seen in males more than 40 years old and presents as scaly red patches or plaques?






8. What DNA virus is associated with exanthem subitum (roseola)?






9. What is the most common one? - Renal calculus type






10. Name the following descriptions associated with bacterial endocarditis: x Retinal emboli






11. What is the term for hyperextension of the PIP and flexion of the DIP joints in rheumatoid arthritis?






12. What is the site of action of the following? - Aldosterone antagonists






13.






14. What nematode is known as whipworms? What is the treatment?






15. What three chemical agents are associated with angiosarcomas of the liver?






16. Have catalase.






17. What is the term for RBCs with smooth undulations on the surface of their membrane - commonly seen in uremia?






18. What is the most common one? - Primary lung cancer






19. What skin condition is a localized proliferation of melanocytes presenting as small - oval - light brown macules?






20. What is the term for processing an APC's pinocytosed material by fusing with a lysosomal granule and cleaving the Ag into peptide fragments?






21. Megaloblastic anemia and thrombocytopenia are signs of what vitamin deficiency?






22. Lucid interval






23. Name the compartment of the mediastinum associated with the following thoracic structures: Left subclavian artery






24. What B cell disorder is characterized by pre - B cells in the bone marrow - no circulating B cells in plasma - normal cell - mediated immunity - low Igs - and appearance by 6 months of age?






25. Which organism releases endotoxins prior to cell death?






26. Do you monitor heparin's therapeutic levels by PT or PTT?






27. In what organ system would you attempt to localize a sign for shaken baby syndrome'? What do you look for?

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28. In the elderly - what happens to total sleep time - percentage of REM sleep - and percentage of NREM sleep?






29. What happens to dopamine levels when we awaken?






30. What disorder is characterized by autoantibodies to IF?






31. Name the primary vesicle the following structures are derived from (proencephalon - mesencephalon - or rhombencephalon) - Cerebral aqueduct






32. Name the antidote - Carbon monoxide (CO)






33. What happens to the tonicity of the urine with increased ADH secretion?






34. What enzyme is needed to activate the following reactions? - Chymotrypsinogen to chymotrypsin






35. What chromosome 4 - AD disorder is a degeneration of GABA neurons in the striatum of the indirect pathway of the basal ganglia?

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36. Name the three benzodiazepines that are not metabolized by the cytochrome P450 enzyme system.






37. How many acetyl CoAs per glucose enter into the TCA cycle?






38. What is used as an index for both adrenal and testicular androgens?






39. What is the statistical term for the proportion of truly nondiseased persons in the screened population who are identified as nondiseased?






40. Name the compartment of the lower extremity and the nerve based on its movements - Flex the hip and extend the knee






41. What factor gets activated in the intrinsic pathway of the coagulation cascade? Extrinsic pathway?






42. What vitamin deficiency causes a glove - and - stocking neuropathy seen in alcoholics?






43. What is the term for ejaculation before or immediately after vaginal penetration on a regular basis?






44. Name the compartment of the lower extremity and the nerve based on its movements - Adduct the thigh and flex the hip






45. Name the cancer associated with the following oncogenes. (Some may have more than one answer) x CDK4






46. In What three areas of the body are sympathetics the predominant tone?






47. What neurotransmitter is presynaptically inhibited by reserpine and guanethidine?






48. What level of mental retardation is characterized by x Being self - supportive with minimal guidance and able to be gainfully employed (includes 85% of the mentally retarded)?






49. What is the term for Ags that activate B cells without T- cell signaling?






50. What water - soluble - vitamin deficiency may result from eating raw eggs?