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USMLE Step 1 Prep

Subjects : health-sciences, usmle-step-1

Instructions:

Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can study here.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Do the duct or the acini cells of the pancreas secrete HCO3-?
Methionine (start) and tryptophan are the only two AAs with only one codon.
Pancreatic delta - cell tumors inhibit CCK secretion
Phase III. It is considered the definitive test.
Duct cells secrete HCO3- - electrolytes - and water. The acini secrete the enzymes necessary for carbohydrate - nucleic acid - protein cleavage - and emulsification of fats.

2. What is the most common one? - Helminthic parasite worldwide
Ascaris lumbricoides
The inner cortex (paracortex) contains the T cells - so it is considered the thymic - dependent area.
Anterior compartment of the leg - deep peroneal nerve
Adenovirus

3. What organelle is responsible for ribosomal RNA synthesis?
Nucleolus. Ribosomal assembly also takes place in the nucleolus.
CD40
Malassezia furfur (treat with selenium sulfide)
Measurement bias

4. Name the most common type or cause - Rectal bleeding
Diverticulosis
Sj
Neuroblastoma
50% - with 50% of them having the child

5. Name the most common type - Learning disability
Dyslexia
1. One cell type 2. One Ab type 3. Random selection of hypervariable regions - and only cells with bound Ag undergo clonal expansion
Trapezius and sternocleidomastoid
EF- Tu and EF- Ts of the 30S ribosomal subunit

6. What is the MCC of the following endocarditis scenarios? - Non - IV drug user
Sensory
Semicircular canal
Staphylococcus aureus
Red muscle

7. What serotonin reuptake inhibitor's major sexual side effect is priapism?
Chlamydia
Squamous cell carcinoma
Trazodone
Melatonin - serotonin - and CCK

8. What endocrine abnormality is characterized by the following changes in PTH - Ca2+ - and inorganic phosphate (Pi)? - PTH increased - Ca2+ decreased - Pi decreased
Secondary hyperparathyroidism (vitamin D deficiency - renal disease)
Infliximab
Respiratory alkalosis (summary: low CO2 - low H+ - slightly low HCO3-)
Renal plasma flow (decrease flow - increase FF)

9. What are the two absolute requirements for the cytochrome P450 enzyme system?
Glucose -6- phosphatase
HMP shunt
NADPH and molecular O 2
Primitive neuroectodermal tumors (i.e. - medulloblastomas and retinoblastomas)

10. What small - facultative gram - negative intracellular rod's transmission is associated with unpasteurized dairy products and undulant fever?
Water
Brucella
P24
Aminophylline

11. WBC casts in the urine
Keratinocytes - the most numerous cells in the epidermis - carry melanin and produce keratin.
MGB (think EARS)
T3 increases both heart rate and cardiac output by increasing the number of Beta - receptors and their sensitivity to catecholamines.
Acute pyelonephritis

12. What are the three most common sites for left - sided heart embolisms to metastasize?
Expiratory reserve volume (ERV)
Giardia lamblia (treat with metronidazole)
Brain - spleen - and kidney
Pancreatic insufficiency

13. How many attacks are needed over how much time before panic disorder is diagnosed?
Osteosarcoma
Dilator pupillae muscle
Need 3 panic attacks over 3 weeks (remember - they come out of the blue.)
Deficiency in surfactant

14. What disorder is associated with spider angiomas - palmar erythema - gynecomastia - testicular atrophy - encephalopathy - abnormalities in clotting factors - and portal HTN?
Cirrhosis
Pseudomonas sp.
Pyelonephritis
Haemophilus influenzae type B

15. What is the only valve in the heart with two cusps?
t the end of the PCT 25% of Na+ - Cl - - K+ is left
Intermediate part of the hemispheres
Mitral (bicuspid) valve
Coxsackie A

16. Which class of antiarrhythmics are potassium channel blockers?
Class III
Right - sided valves
Velocity is inversely related to cross - sectional area.
Lingual nerve of CN V3

17. From what pharyngeal pouch is the following structure derived? - Superior parathyroid gland and ultimobranchial body of the thyroid
Blood
Fourth M PITS for pharyngeal pouch derivatives
DiGeorge syndrome
The scaphoid is the most commonly fractured and the lunate is the most commonly dislocated.

18. Name the valve abnormality based on the following criteria: x Diastolic murmur; increased preload - stroke volume - and aortic pulse pressure; decreased coronary blood flow; no incisura; and peripheral vasodilation
Risk factors for cervical cancer
C3 deficiency
Bainbridge reflex
Aortic insufficiency

19. Are salivary secretions hypertonic - hypotonic - or isotonic?
Hypotonic - because NaCl is reabsorbed in the salivary ducts
They are preganglionic sympathetic axons. They are white because they are myelinated.
NE
Hematoxylin

20. What is the term to describe a decrease in the cell size and function usually associated with disuse?
Autosomal recessive
Mycoplasma pneumoniae
They chronically inhibit ADH secretion; when there is a decrease in the blood volume - the stretch receptors send fewer signals - and ADH is secreted.
Atrophy. Disuse can also be due to immobilization - ischemia - aging - and a host of other causes.

21. A Japanese man has weight loss - anorexia - early satiety - epigastric abdominal pain - and a palpable left supraclavicular lymph node. On endoscopy you find a large - irregular ulcer with elevated margins on the lesser curvature of the stomach. What
Adult polycystic kidney disease
Gastric carcinoma
Rabies
Secondary hypocortisolism (pituitary)

22. What paraphilia is defined as x Deriving sexual pleasure from watching others having sex - grooming - or undressing?
Voyeurism
ELISA test
Phase 1
1. One cell type 2. One Ab type 3. Random selection of hypervariable regions - and only cells with bound Ag undergo clonal expansion

23. What are the three signs of morphine overdose?
1. Pinpoint pupils 2. Decreased respiratory rate 3. Coma
Lung and bronchus cancer
Ixodes (also the vector for Lyme disease)
Ethyl alcohol

24. What is the most common lysosomal storage disorder?
Gaucher disease
Early distal tubule
Gout
Hypoxanthine (remember - IMP is a precursor for AMP and GMP)

25. What is the term for neurologic signs consistent with a cerebrovascular accident but lasting 24 hours with full recovery?
Herpes virus
Type I symptoms (positive); schizophrenics have them - but otherwise healthy persons do not.
Proencephalon
Transient ischemic attack

26. What are the three characteristics of ADHD?
1. Short attention span 2. Impulsivity 3. Hyperactivity
Oxytocin
Because RPF is markedly decreased - while GFR is only minimally diminished; this results in an increase in FF (remember FF = GFR/RPF).
Hemangioblastoma

27. Which M- protein strain of Streptococcus pyogenes is associated with acute glomerulonephritis?
Blood
Gametocytes
S2 - S3 - S4
M12 strains

28. What substrate is built up in Niemann - Pick disease?
Poxvirus
Sphingomyelin
Anorgasmia. (The overall prevalence is 30%.)
Type II hypersensitivity reaction

29. What type of bilirubin is found in neonatal jaundice?
Infection
Myeloperoxidase
Indirect or unconjugated
Progressive multifocal leukoencephalopathy

30. What is the size of a positive PPD test for the following? (Reactive) x Posttransplantation patient taking immunosuppressive agents
ICF volume decreases when there is an increase in osmolarity and vice versa.
>5 mm
Are inactivated vaccines available in the United States
Hapten; if it is coupled with a carrier - it may become immunogenic.

31. Is a subdural hematoma an arterial or venous bleed?
Anaerobes
MstII; changing codon 6 (from A to T) destroys the restriction site.
Gastric ulcer
Subdural hematoma is a rupture of the cerebral veins where they enter the superior sagittal sinus.

32. What is determined by the secondary structure of an AA?
Surface tension - the force to collapse the lung - is greatest at the end of inspiration.
Inhibin - m
The folding of an AA chain
X- linked recessive

33. In what compartment of the thigh is the profundus femoris artery found?

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34. What nucleus of the hypothalamus is the satiety center - regulating food intake?
Ventromedial nucleus; lesions here result in obesity.
Pneumocystis carinii
Fluconazole
Tetany

35.
prior to birthThe foramen ovale closes just...
Clindamycin
One pair with three to five coccygeal vertebrae. Totaling 31 pairs of spinal nerves.
Hematoxylin

36. When a person goes from supine to standing - what happens to the following? - Dependent venous blood volume
Increases Remember - the carotid sinus reflex attempts to compensate by increasing both TPR and heart rate. -------------------------------------------------------------------------------
Duct cells secrete HCO3- - electrolytes - and water. The acini secrete the enzymes necessary for carbohydrate - nucleic acid - protein cleavage - and emulsification of fats.
Mitral valve prolapse
Alcoholics Anonymous

37. What mineral is a component of cytochrome a/a3?
Copper
Antigenic determinant (epitope). (Idiotypes bind to epitopes.)
hCG
Trichuris trichiura is treated with albendazole.

38. Name the cancer associated with the following chemical agents. (Some may have more than one answer.) x Benzenes
Four high energy bonds - two from ATP in AA activation and two from GTP
Leukemias
Apoptosis (Remember - there is a lack of inflammatory response.)
Heart rate determines the diastolic interval - and contractility determines the systolic interval.

39. Is cigarette smoking associated with transitional cell carcinoma of the bladder?
Increasing blood flow is the only way to increase O2 delivery in the coronary circulation because extraction is nearly maximal during resting conditions.
Yes. It is also a cause of cancers of the lung - esophagus - ureter - and kidney - just to Name a few.
14 days
Glucagon and epinephrine

40. What type of erythema do you see in x Ulcerative colitis?
Yes. This is done to help prevent underreporting out of fear of lawsuit. Remember that it is your duty to protect the child first - not worry about legal responsibility.
Patients with cystic fibrosis have a mutation in the chloride channel protein in the CFTR gene on chromosome 7.
Erythema nodosum
Transcription (C comes before L in the alphabet - and transCription comes before transLation)

41. Which cestode in raw or rare beef containing cysticerci results in intestinal tapeworms?
Proencephalon diencephalon derivative
Glossopharyngeal nerve
Taenia saginata
Itraconazole

42. What form of alcohol causes blindness?
Methanol (wood alcohol)
Ipsilateral loss at and below the level of the lesion
Stercobilin
Achondroplasia

43. If capillary hydrostatic pressure is greater than oncotic pressure - is filtration or reabsorption promoted?
Filtration; if hydrostatic pressure is less than oncotic pressure - reabsorption is promoted.
Laminin
Short - chain fatty acids
Sj

44. What is the triad of Reiter syndrome?

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45. Name the most common type or cause - Nephrotic syndrome in children
Hematoxylin
Lipoid nephrosis
REM
7

46. Name the valve abnormality based on the following criteria: x Systolic murmur - increased preload and afterload - decreased aortic pulse pressure and coronary blood flow
reflexes
Aortic stenosis
Twelve pairs through twelve thoracic vertebrae. Totaling 31 pairs of spinal nerves.
Live vaccines

47. What factors are needed for translocation in eukaryotes?
CN V1 carries the sensory and CN VII carries the motor component of the blink reflex.
Fusobacterium
Motor nucleus of CN V
EF-2 and GTP

48. What do the following values indicate? - LD50
Water
Lethal dose for 50% of drug takers (median lethal dose)
Cyanocobalamin (B12)
1. Temporal 2. Zygomatic 3. Buccal 4. Mandibular 5. Cervical (Two Zebras Bit My Clavicle.)

49. What is the most common one? - Site of a cerebral infarct
Dyslexia
The rate of Beta- oxidation
Middle cerebral artery
Muscles of the internal eye

50. What type of damage to the kidneys is caused by drinking ethylene glycol (antifreeze)?
igantism
Nephrotoxic oxylate stones
Biotin. Avidin is found in raw egg whites.
Adult T- cell leukemia