Test your basic knowledge |

USMLE Step 1 Prep

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What component of the renin - angiotensin - aldosterone axis increases sodium reabsorption in the proximal convoluted tubules and increases thirst drive?






2. What stage of sleep is associated with somnambulism?






3. What carcinoma produces hematuria - flank pain - and a palpable mass?






4. What are the two leading causes of cancer - related death in men?






5. Name the form of spina bifida - An open neural tube lying on the surface of the back






6. Should information flow from the patient to the family or vice versa?

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7. What two receptors in the chemoreceptor trigger zone lead to vomiting when stimulated?






8. What paraphilia is defined as x Deriving sexual pleasure from watching others having sex - grooming - or undressing?






9. What are the rules of 2 for Meckel diverticulum?






10. What two factors result in the apex of the lung being hypoperfused?






11. What cell in bone is a part of the mononuclear phagocytic system?






12. What is the most common one? - Malignant thyroid tumor






13. Why is O2 content depressed in anemic patients?






14. What disorder causes joint stiffness that worsens with repetitive motion - crepitus - effusions - and swelling and commonly affects the knees - hips - and spine?






15. A suspected dermatophyte infection is stained with KOH. What spore type do you expect to see?






16. Name the most common type - Learning disability






17. How many pairs of spinal nerves are associated with x Cervical vertebrae?






18. What is the name of the major chemotactic agent released from x Bacteria?






19. Name the cancer associated with the following oncogenes. (Some may have more than one answer) x et






20. What is the most common one? - Primary malignant tumor of the lungs






21. What rate removes any difference between two populations - based on a variable - to makes groups equal?






22. Which chromosome is associated with MHC genes?






23. What is the name of the superficial subcutaneous fascia of the abdomen containing fat?

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24. Are the following responses associated with histamines H1 or H2 receptor activation? - Bronchial smooth muscle activity






25. Name the ventricular muscle membrane channel: x Open at rest; depolarization is stimulus to close; begin to reopen during the plateau phase and during repolarization






26. What is the rate - limiting step in the production of steroids?






27. What type of erythema do you see in x Ulcerative colitis?






28. How many bases upstream is the eukaryotic TATA box promoter?






29. What part of the heart forms x Apex?






30. What is the term when the brachial artery is compressed - resulting in ischemic contracture of the hand?

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31. What are the three Beta - lactamase inhibitors?






32. Which of the following is not a risk factor for cholesterol gallstones: pregnancy - OCP use - female gender - hemolytic anemia - cirrhosis - and obesity? (May be more than one answer.)






33. What pH (acidotic or alkalotic) is needed for pepsinogen to pepsin conversion?






34. Risk factors for endometrial carcinoma.






35. How can you differentiate between a medial temporal lobe and a hippocampal lesion based on memory impairment?






36. Regarding the venous system - what happens to blood volume if there is a small change in pressure?






37. What is the term for the strength of the association between Ags and Abs?






38. Does Cushing syndrome or Cushing disease have elevated ACTH levels and cortisol suppression with dexamethasone?

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39. Is the following description characteristic of competitive or noncompetitive antagonists: parallel shift to the right on a dose - response curve - complete reversibility with increase of the dose of the agonist drug - and capacity to decrease the pot






40. Name the compartment of the mediastinum associated with the following thoracic structures: Brachiocephalic vein






41. What is the term for a congenital absence of the ganglionic cells of the Auerbach and Meissner plexus in the rectum and sigmoid colon?






42. What factors are needed for elongation in eukaryotes?






43. What are the three functions of surfactant?






44. What cytokine do CD4 T cells secrete to activate B cells when the specific peptide in the groove of the MHC II molecule interacts with the TCR?






45. Which thalamic nucleus receives auditory input from the inferior colliculus?






46. What phase of the cell cycle are the following antineoplastic agents specific for? - Alkylating agents






47. What is the term for ventilation of unperfused alveoli?






48. What virus is associated with the Norwalk agent?






49. Serious psychiatric illness is more common _______ than childbirth.






50. Place in order from fastest to slowest the rate of gastric emptying for CHO - fat - liquids - and proteins.