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USMLE Step 1 Prep

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What type of cell is surrounded by mineralized bone?






2. What muscle or muscles are innervated by the following nerves? - Long thoracic nerve






3. What are the three signs of morphine overdose?






4. Would a G- C or an A- T rich dsDNA sequence have a higher melting point? Why?






5. Regarding the Lac operon - for What do the following genes code? - Z gene






6. As what AAs do muscles send nitrogen to the liver?






7. What is the term for vitamin D deficiency prior to epiphyseal fusion?






8. What component of the trigeminal nuclei x Supplies the muscles of mastication?






9. What are the two ketogenic AAs?






10. What sphingolipid cannot be produced without sialic acid and amino sugars?






11. What is the most common one? - Type of hernia seen in males more than 50 years old






12. What are the two factors that affect alveolar PCO2 levels?






13. What vitamin is necessary for epithelial health?






14. What lysosomal enzyme is deficient in x Tay- Sachs disease?






15. What scale has a true zero point - graded into equal increments - and also orders them?






16. In what condition do you see dimpling on the kidney's surface?






17. What are the three main components of amyloid?






18. What do the following values indicate? - ED50






19. What blotting technique uses the following for analysis? - DNA






20. Which medication requires an acidic gastric pH for activation to form a protective gel - like coating over ulcers and GI epithelium?






21. What is the term for Ags that activate B cells without T- cell signaling?






22. What is the MCC of the following endocarditis scenarios? - Following biliary infections






23. ADH is secreted in response to What two stimuli?






24. What are the four components of the basement membrane?






25. What is the first sign of megaloblastic anemia on a peripheral blood smear?






26. What happens to the following during skeletal muscle contraction? - I band






27. What type of collagen is abnormal in patients with osteogenesis imperfecta?






28. What gene stimulates apoptosis when DNA repair is unable to be done?






29. What leukemia is characterized by Philadelphia chromosomal translocation (9;22); massive splenomegaly; peripheral leukocytosis (commonly > 100 - 00); decreased LAP levels; and nonspecific symptoms of fatigue - malaise - weight loss - and anorexia?






30. What DNA viral disease is associated with aplastic crisis in patients with sickle cell anemia?






31. What happens to affinity if you increase Km?






32. A 20-year - old woman who was recently diagnosed with a sexually transmitted disease goes to the ER with a tender - painful - swollen - and erythematous knee (monoarticular). What organism is the likely culprit?






33. What happens to the Ab specificity when class switching occurs in mature B cells?






34. What antitubercular agent causes loss of red - green visual discrimination?






35. Shuffling gait - cogwheel rigidity - masklike facies - pill - rolling tremor - and bradykinesia describe what form of dementia?

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36. What type of hypersensitivity is an Ab - mediated response against our own cells - receptors - or membranes via IgG or IgM?






37. How many months in How many years must a person cough with copious sputum production for the diagnosis of chronic bronchitis to be made?






38. What neurotransmitter is associated with sedation and weight gain?






39. What negative sense RNA virus is associated with cough - coryza - and conjunctivitis with photophobia?






40. Name the type of graft described by these transplants: x From one species to another






41. Name the antimicrobial agent whose major side effect is listed - Hemolytic anemia






42. Prevents restriction endonuclease from cutting its own chromosomes.






43. Are hydrolysis - oxidation - and reduction phase I or II biotransformations?






44. What is the most common one? - Site of Crohn disease






45. What is the term for RBC fragments?






46. What IL down - regulates cell mediated immunity?






47. Name the valve abnormality based on the following criteria: x Diastolic murmur; increased preload - stroke volume - and aortic pulse pressure; decreased coronary blood flow; no incisura; and peripheral vasodilation






48. Name the most common type or cause - Chronic metal poisoning






49. What happens to extracellular volume with a net gain in body fluid?






50. What happens to prevalence as the number of long - term survivors increases?