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USMLE Step 1 Prep

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Which aminoglycoside is used only topically because it is too toxic for systemic use?






2. What viral infection in patients with sickle cell anemia results in aplastic crisis?






3. What vertebral level is marked by the xiphoid process?






4. How do the corticobulbar fibres of CN VII differ from the rest of the CNs?






5. What are the most common causes of osteomyelitis x In drug addicts?






6. Where does Beta - oxidation of very long chain fatty acids begin?






7. What type II hypersensitivity disorder is defined as x Autoantibodies directed against RBC Ag I?






8. Name the cancer associated with the following oncogenes. (Some may have more than one answer) x hst -1 and int -2






9. What somatoform disorder is described as x Preoccupied with illness or death - persisting despite reassurance - lasting longer than 6 months?

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10. What are the five components of portal HTN?






11. What form of estrogen is of placental origin?






12. What HIV enzyme produces a dsDNA provirus?






13. What causes slow writhing movements (athetosis)?






14. What is the term for production of a DNA copy from an RNA molecule?






15. What IL is important in myeloid cell development?






16. What enzyme catalyzes the rate - limiting step in cholesterol metabolism?






17. What enzyme is deficient in the following glycogen storage disease? - von Gierke's disease






18. What branch off the vertebral artery supplies x The ventrolateral two - thirds of the cervical spinal cord and the ventrolateral part of the medulla?






19. What ovarian carcinoma is characterized by psammoma bodies?






20. What is the label given to an individual whose IQ is x Below 69






21. What genus of bacteria is described by catalase - positive - gram - positive cocci in clusters?






22. Does O2 or CO2 have a higher driving force across the alveolar membrane?






23. What virus causes hoof - and - mouth disease?






24. What is the fluid of the posterior compartment of the eye?






25. What is the amount in liters and percent body weight for the following compartments? - Interstitial fluid






26. Name the three postganglionic sympathetic ganglia that receive input from thoracic splanchnics.

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27. What is the most common one? - Form of muscular dystrophy






28. Name the area of the cerebral cortex affected by the description of the effects - symptoms - and results of the lesion - Withdrawn - fearful - explosive moods - violent outbursts - and loss of inhibitions






29. What substance is secreted by parietal glands and is required for life?






30. Prevents restriction endonuclease from cutting its own chromosomes.






31. What type II hypersensitivity disorder is defined as x Autoantibodies directed against the TSH receptor?






32. If the radius of a vessel is decreased by half - what happens to the resistance?






33. What form of diabetes insipidus is due to an insufficient amount of ADH for the renal collecting ducts?






34. What AD dementia has a defect in chromosome 4 - onset between the ages of 30 and 40 - choreoathetosis - and progressive deterioration to an infantile state?






35. Name the DNA virus: x Partially dsDNA circular; enveloped; virion - associated polymerases; has RNA intermediate; replicates in the nucleus






36. Which drug is used to treat opioid withdrawal - ADHD - and sometimes Tourette's syndrome?






37. What form of depression is due to abnormal metabolism of melatonin?






38. Which region of the variable domain comprises the Ag - binding site of the Ab?






39. What adrenal enzyme deficiency can be summed up as a mineralocorticoid deficiency - glucocorticoid deficiency - and an excess of adrenal androgens?






40. What are the primary neurotransmitters at the following sites? - Brainstem cells






41. What neurotransmitter is presynaptically inhibited by reserpine and guanethidine?






42. What is the rate - limiting step in a conduction of a NMJ?






43. What AR syndrome is due to a deficiency of glycoprotein Ib - resulting in a defect in platelet adhesion?






44. What receptors are the best markers for NK cells?






45. What component of the ANS is responsible for dilation of the blood vessels in the erectile tissue of the penis - resulting in an erection?






46. Is encapsulated.






47. Which subtype of AML is most commonly associated with Auer rods?






48. What branches of CN X are the sensory and motor components of the cough reflex? Be specific.






49. What is the most common one? - Site of ulcerative colitis






50. Which muscarinic receptor uses a decrease in adenyl cyclase as its second messenger?