Test your basic knowledge |

USMLE Step 1 Prep

Subjects : health-sciences, usmle-step-1

Instructions:

Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can study here.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. What antipsychotic movement disorder can occur at any time and is characterized by a subjective sense of discomfort that brings on restlessness - pacing - sitting down - and getting up?
Medial collateral ligament
cDNA libraries are derived from mRNA - are continuous - and contain no introns or regulatory elements.
Akathisia
PKU

2. What is the most common opportunistic infection of the CNS in HIV?
Bronchogenic carcinoma
Toxoplasmosis
Alcoholics Anonymous
CN V1 - the occulomotor division of the trigeminal nerve - is the sensory component of the corneal reflex.

3. What equals the total tension on a muscle minus the preload?
Monocytosis
Afterload
'Lady between two Majors': latissimus dorsi - pectoralis major - and teres major
Substance P. (Opioids relieve pain in part by blocking substance P.)

4. What is the drug of choice in treating a patient with hyperuricemia due to underexcretion of uric acid?
The deepest sleep levels (stage 3 and 4) occur mostly in the first half of sleep.
robenecid - a uricosuric agent
Sinus venosus
Size

5. What is the most common one? - Site of a cerebral infarct
The conversion of tyrosine to dopamine in the cytoplasm
Middle cerebral artery
Toxic or viral hepatitis
Potency

6. What disease has IgG autoantibodies - occurs in women more than men - and includes exophthalmos - pretibial myxedema - nervousness - heart palpitations - and fatigue?
Glucose
Microglia. All others are neuroectodermal derivatives.
Gain of hypertonic fluid (mannitol or hypertonic saline)
Graves disease

7. What antiviral agents inhibit neuraminidases of influenza A and B?
Sporothrix schenckii
CD16 and CD56
Zanamivir and oseltamivir
Gastric cancer

8. What subtype of IgG does not activate complement cascade?
Chloramphenicol
IgG4
Osteosarcoma
Burkitt lymphoma

9. Is there a shift in p50 values with anemia? Polycythemia?
The p50 value does not change in either anemia or polycythemia; the main change is the carrying capacity of the blood.
Immunogenicity; antigenicity refers to Ab/lymphocyte reaction to a specific substance.
Proencephalon diencephalon derivative
Duchenne muscular dystrophy

10. Name the structure that enters or exits the following foramina: x Internal auditory meatus
CN VII and VIII
Complex I
LH
Methylene blue

11. What is the DOC for severe infections with Sporothrix - Mucor - Histoplasma - Cryptococcus - Candida - and Aspergillus?
Appendix (second is terminal ileum)
Increased secretion of GH postpuberty leading to acromegaly.
Amphotericin B
First - pass metabolism and acid lability

12. People who believe that luck - chance - or the actions of others control their fate have an internal locus of control.
Histiocytosis X
Chlamydia
Streptococcus pneumoniae
Social learning theory

13. What type of error is made if you reject the null hypothesis when it is true?

Warning: Invalid argument supplied for foreach() in /var/www/html/basicversity.com/show_quiz.php on line 183

14. What enzyme catalyzes the rate - limiting step in fatty acid oxidation?
Metronidazole
REM sleep occurs more often in the second half of sleep. The amount of REM sleep increases as the night goes on.
1. Autoimmune hypersplenism 2. Trauma 3. Anemia 4. Spherocytosis 5. Sickle cell anemia
Carnitine acyltransferase - I

15. To What does aldose reductase convert galactose?
Galactitol
Thrombocytopenia - eczema - and immunodeficiency is the triad of this X- linked recessive disorder.
Arterioles
None; they are the storage sites for ADH and oxytocin.

16. What is the most common one? - Cardiac anomaly in children
42 L - 67% of body weight
Being a white male
PDA
Pseudomonas sp.

17. Name the thalamic nucleus based on its input and output - Input from globus pallidus and the cerebellum; output to the primary motor cortex
Ventral lateral nucleus
S phase
Alcohol consumption
Pituitary hypogonadism

18. Name the most common type or cause - Painless hematuria
Meningomyelocele All except occulta cause elevated - fetoprotein levels.
Lead - time bias (remember - patients don't live longer with the disease; they are diagnosed sooner.)
Aorta - azygos vein - and thoracic duct Remember: 1 at T8 - 2 at T10 - and 3 at T12
Renal cell carcinoma

19. Where do sperm go for maturation?
Ductus epididymis - Which is lined by pseudostratified epithelium with stereocilia.
Eight pairs through seven cervical vertebrae. Totaling 31 pairs of spinal nerves.
Pneumocystis carinii
Subdural hematoma is a rupture of the cerebral veins where they enter the superior sagittal sinus.

20. What area of the retina consists of only cones and has the greatest visual acuity?
Fovea
Graves disease
Four high energy bonds - two from ATP in AA activation and two from GTP
CD16 and CD56

21. What happens to the lung if the intrapleural pressure exceeds lung recoil?
Schizoid
Increase in erythropoietin and increase in 2 - 3- BPG - also called 2 - 3- diphosphoglycerate (2 - 3- P2Gri) (increase in glycolysis)
Squamous cell carcinoma
The lung will expand; also the opposite is true.

22. What is the term for Candida infection of the oral mucosa?
Thrush
Molluscum contagiosum
Pasteurella - Brucella - Legionella - and Francisella (all of the - ellas)
Thyroid hormones

23. What term describes the volume of plasma From which a substance is removed over time?
Squamous cell carcinoma
Adenocarcinoma (because of Barrett esophagus)
D1 receptor; inhibition of the direct pathway occurs through the D2 receptors.
Clearance

24. With an increase in arterial systolic pressure - what happens to x Vessel compliance?
Decreases
Selection bias
The pulmonary vein - which carries oxygenated blood from the lung to the left atrium.
Dilation of afferent arteriole

25. Which bacteria are associated with the following pigment production? - Yellow pigmentation
Staphylococcus aureus
Cytochrome a/a3
Ipsilateral flaccid paralysis
Glucocerebrosidase

26. What Brodmann area is associated with x Visual association cortex?
Preoperational (2-6 years)
Areas 18 and 19
Vesicle (e.g. - poison ivy)
Calcarine sulcus

27. What are the four reasons for hypochromic microcytic anemia with a low MCV?
Stimulus generalization must stop. (Pairing of the unconditioned stimulus and the conditioned stimulus must cease.)
The second pharyngeal pouch and groove
Osteogenesis imperfecta
1. Sideroblastic anemias (i.e. - porphyrin and heme synthesis disorders) 2. Thalassemia 3. Iron deficiency 4. Lead poisoning

28. In regard to motor development during infancy - choose the motor response that happens first - Proximal or distal progression
Trapezius and sternocleidomastoid
Vaginismus; it is the female counterpart of premature ejaculation.
Sigma factor
Proximal to distal progression

29. What happens to capillary oncotic pressure with dehydration?
Oncotic pressure increases because of the removal of water.
Carnitine acyltransferase I
Duchenne muscular dystrophy (Remember - Becker's is slower in progress - less severe - later in onset - and lacks cardiac involvement.)
Leiomyoma

30. Name the most common type or cause - Neonatal bowel obstruction
Parasympathetic stimulation - via the vagus nerve - results in bronchoconstriction - whereas sympathetic stimulation results in bronchodilation.
Cytochrome c
Estrone
Hirschsprung disease

31. Name the phase of the ventricular muscle action potential based on the following information: x Slow channels open - allowing calcium influx; voltage - gated potassium channels closed; potassium efflux through ungated channels; plateau stage
Listeria monocytogenes
Dominant temporal lobe
Phase 2
Type I symptoms (positive); schizophrenics have them - but otherwise healthy persons do not.

32. Induces the cytochrome P-450 enzymes.
HDL
Papillary carcinoma
Ethyl alcohol
HHV-8

33. What is the most common one? - Renal calculus type
Calcium oxylate
Renal cell carcinoma
Mitosis
Berylliosis

34. What ring is a weblike narrowing of the gastroesophageal junction?
Schatzki ring
Granulose cells secrete progesterone. After fertilization the granulose cells form from follicular cells.
Wegener granulomatosis
Macula densa

35. What are the two most common AAs found in histones?
Liver - kidneys - and pituitary gland via 5' deiodinase enzyme
Lysine and arginine
Magnesium ammonium phosphate (struvite)
Dorsal motor nucleus of CN X

36. Do the following structures pick up stain from hematoxylin or eosin? - Collagen
Eosin
Coarctation of the aorta
1. Increased synthesis and secretion of oxytocin 2. Increased release of PIF by the hypothalamus 3. Inhibition of GnRH (suppressing FSH/LH) 4. Milk secretion
Diverticulosis

37. Streaky ovaries
Bile salts are actively reabsorbed in the distal ileum.
Turner syndrome
Parasympathetic
1. Increased synthesis and secretion of oxytocin 2. Increased release of PIF by the hypothalamus 3. Inhibition of GnRH (suppressing FSH/LH) 4. Milk secretion

38. What type of Plasmodium affects x RBCs of all ages?
Proencephalon
Plasmodium falciparum
Sporozoites
Subdural hematoma is a rupture of the cerebral veins where they enter the superior sagittal sinus.

39. What hematologic malignancy is treated with the monoclonal antibody rituximab?
Non - Hodgkin lymphoma
Factors II - VII - IX - and X and proteins C and S.
The parafollicular cells of the thyroid (C cells) release calcitonin in response to hypercalcemia.
Janeway lesions

40. What vitamin is a cofactor of aromatic amino acid decarboxylase and decreases the efficacy of L- dopa if used concomitantly?
Puborectalis
Sj
Vitamin B 6 (pyridoxine)
Carbamazepine

41. Name the laryngeal muscle described by the following: x Pulls the arytenoids cartilages closer to the thyroid - relaxing the vocal ligaments and thereby decreasing the pitch
Thyroarytenoid muscles
Cortisol
Labile
The thyroid gland

42. What tumor marker is associated with seminomas?
Parkinson disease
Placental alkaline phosphatase
Hormone - sensitive lipase - Which breaks down triglyceride into glycerol and free fatty acid
Lung recoil - being a force to collapse the lung - increases as the lung enlarges during inspiration.

43. How are resistance and viscosity related regarding flow?
Viscosity and resistance are proportionally related. The greater the viscosity - the greater the resistance is on the vessel.
These are the gross pathologic changes associated with Alzheimer's disease.
Enterokinase
Increase (5- HT and dopamine levels do the same)

44. A chronic alcohol abuser goes to the ER with weakness - a sore - beefy red tongue - loss of vibration and position sense - arm and leg dystaxia - elevated levels of methylmalonic acid in the urine - and anemia with an MCV above 105 fL. What is your d
During REM sleep
The odontoid process of C2
I- cell disease is a result of a genetic defect affecting the phosphorylation of mannose residues.
Subacute combined degeneration of the spinal cord is treated with IM vitamin B12 injections. If treatment is working - you will see an increased reticulocyte count on the peripheral smear in about 5 days.

45. What autoimmune liver disease is characterized by affecting a middle - aged woman with jaundice - pruritus - fatigue - xanthomas - increased direct bilirubin levels - and antimitochondrial Abs?
Primary biliary cirrhosis
DiGeorge's syndrome
Utricle and saccule
Adenocarcinoma of the cervix

46. What is the main type of cell involved in cellular immunity?
Cystadenoma
T lymphocyte
IgA - IgD - IgE - IgG - and IgM
M- cells

47. Name the macrophages by location: x Lungs
Alveolar macrophages
Ego syntonic
The Fc region of IgG and C3b
Nodes of Ranvier

48. How many pairs of spinal nerves are associated with x Lumbar vertebrae?
Polycystic kidney disease of childhood
Alveolar dead space
Five pairs through five lumbar vertebrae. Totaling 31 pairs of spinal nerves.
Liver - kidneys - and pituitary gland via 5' deiodinase enzyme

49. What hormone disorder is characterized by the following abnormalities in sex steroids? - LH? - and FSH?? - Sex steroids - LH - FSH ?
Lung cancer
Primary hypogonadism (postmenopausal women)
Liver
Alveoli; they are part of the respiratory portion.

50. The DSM- IV- TR is scored on the basis of five axes of diagnosis. In What axis would you place x Psychosocial and environmental problems (stressors)?
Axis IV
Ligament of Treitz
REM
Afterload