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USMLE Step 1 Prep

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Which anticonvulsant causes gingival hyperplasia?






2. Pseudopalisades






3. What disorder is due to a 5-- reductase deficiency - resulting in testicular tissue and stunted male external genitalia?






4. What is released from the mitochondria to trigger apoptosis?






5. What are the rules of 2 for Meckel diverticulum?






6. What DNA excision and repair enzyme is deficient in patients with xeroderma pigmentosum?






7. What are the primary neurotransmitters at the following sites? - Postganglionic sympathetic neurons






8. What form of endocarditis do patients with SLE commonly encounter?






9. Which shuttle is used to bring fatty acyl CoA from the cytoplasm for ketogenesis?






10. Which class of antihypertensives produces angioedema - hyperkalemia - and a dry cough?






11. What small gram - negative aerobic rod requires Regan - Lowe or Bordet - Gengou medium for growth?






12. What is the name of the process that ensures that each B cell produces only one heavy- chain variable domain and one light chain?






13. What is an elevated - fluid - filled cavity between skin layers up to 0.5 cm?






14. What has occurred to the renal arterioles based on the following changes in the GFR - RPF - FF - and glomerular capillary pressure? - GFR ? - RPF ? - FF normal - capillary pressure ?






15. What is the only sphingolipid that contains choline and PO4?






16. What is the respiratory compensation mechanism for metabolic alkalosis?






17. What myeloid disorder is characterized by increased hematocrit - blood viscosity - basophils - and eosinophils; intense pruritus; and gastric ulcers due to histamine release from basophils - increased LAP - and plethora?






18. Name the lung measurement based on the following descriptions: x Amount of air in the lungs after maximal inspiration






19. At what vertebral level does the trachea bifurcate?






20. Name the cancer associated with the following tumor markers. (Some may have more than one answer.) x Placental alkaline phosphatase






21. Avidin decreases the absorption of what vitamin?






22. What protein prevents ssDNA from reannealing during DNA replication?






23. What thyroid enzyme is needed for oxidation of I- to I'?






24. What toxin ADP- ribosylates via Gi to increase cAMP?






25. What is the effect of insulin on intracellular K+ stores?






26. Myelin is produced by which cells in the PNS? In the CNS?






27. Is spousal abuse a mandatory reportable offense?






28. What are the two absolute requirements for the cytochrome P450 enzyme system?






29. In which region of the lung are 75% of the pulmonary infarcts seen?






30. What three factors increase simple diffusion?






31. What is the term for the external urethra opening onto the dorsal surface of the penis?






32. What is the only glycosaminoglycan (GAG) that binds to the linker portion of the proteoglycan?






33. What CNs are affected if there is a lesion in x The upper medulla?






34. What is the only important physiological signal regulating the release of PTH?






35. What protein carries free fatty acids to the liver?






36. Name the form of spina bifida - Defect in the vertebral arch






37. What type of scheduled reinforcement states that after a desired response - the reinforcement is given x Varying in time?






38. Name the aphasia based on these characteristics: x Both Broca's and Wernicke's areas damaged by lesion in the presylvian speech area; trouble repeating statements; poor comprehension with telegraphic speech






39. What is the term for a delay in the onset of normal IgG synthesis seen in the fifth to sixth month of life?






40. What is the most common form of elderly abuse?






41. What ocular muscle x Abducts the eyeball and is involved in horizontal conjugate gaze?






42. Name the associated chromosome - Cri - du - chat






43. If the ratio of a substance's filtrate and plasma concentrations are equal - What is that substance's affect on the kidney?






44. What urinary metabolite is elevated in pheochromocytoma?






45. What is a sign of a Sertoli cell tumor in a man?






46. What abdominal muscle runs in a posteroinferior direction - splits to contribute to the rectus sheath - contributes to the formation of the conjoint tendon - and in men gives rise to the middle spermatic fascia and the cremasteric muscle of the sperm






47. Name the cancer associated with the following oncogenes. (Some may have more than one answer) x L- myc






48. What subset of CD4 helper T- cell function is helping the development of CD8 T cells?






49. What is the label given to an individual whose IQ is x 90 to 109






50. What is the most common one? - Primary malignant tumor in the liver