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USMLE Step 1 Prep

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What IL - produced by macrophages - is chemotactic for neutrophils?






2. What two receptors in the chemoreceptor trigger zone lead to vomiting when stimulated?






3. Name the cancer associated with the following oncogenes. (Some may have more than one answer) x c - myc






4. What enzyme is blocked by hydroxyurea?






5. What part of the heart forms x Left border?






6. What is the major hormone produced in the following areas of the adrenal cortex? - Zona fasciculata






7. What is the most common one? - Malignancy in children






8. What a1- agonist - not inactivated by catechol - O- methyl transferase (COMT) - is used as a decongestant and for treatment of paroxysmal atrial tachycardia?






9. What neuropsychologic test has five basic scales testing for the presence and localization of brain dysfunction?






10. What is the term to describe how easily a vessel stretches?






11. What artery turns into the dorsalis pedis when it crosses the extensor retinaculum?






12. What form of Plasmodium species affects the liver?






13. Is the coding or the template strand of DNA identical to mRNA (excluding the T/U difference)?






14. What complement factor deficiency leads to x Leukocyte adhesion deficiency with poor opsonization?






15. How many oogonia are present at birth?






16. Are elevated alkaline phosphatase and decreased phosphorus and calcium levels more consistent with osteoporosis or osteomalacia?






17. Based on the following information - is the renal transplantation rejection acute - chronic - or hyperacute? - Months to years after transplantation; gradual onset of HTN - oliguria - and azotemia; seen as intimal fibrosis of the blood vessels and in






18. Where is the lesion that produces these symptoms when a patient is asked to look to the left? - Left eye can't look to the left






19. Name the area of the cerebral cortex with the function described: x Motivation - memory - emotions - violent behaviors - sociosexual behaviors - conditioned responses






20. What regulates the rate of ketone body formation?






21. What type of resistance system (i.e. - high or low) is formed when resistors are added in parallel?






22. What enzyme is needed to activate the following reactions? - Chymotrypsinogen to chymotrypsin






23. A 20-year - old woman goes to the ER with ptosis - diplopia - weakness in her jaw muscles when chewing - and muscle weakness with repeated use. What is your diagnosis?






24. Name the most common type or cause - Right heart failure






25. What is the term for how well a drug produces its desired response?






26. What IL down - regulates cell mediated immunity?






27. What drug blocks intragranular uptake of NE?






28. What are the three signs of morphine overdose?






29. The probability that a person with a positive test result is truly positive refers to what value?






30. What is defined as a general estimate of the functional capacities of a human?






31. Name the most common type or cause - Viral pneumonia leading to death






32. Name the most common type or cause - Restrictive cardiomyopathy






33. What is the only diuretic that works on the blood side of the nephron?






34. Why is there an increase in FF if the GFR is decreased under sympathetic stimulation?






35. Which antispasmodic blocks the release of Ca 2+from the SR and is used in the treatment of malignant hyperthermia?






36. Which class of antihyperlipidemics would you avoid for a patient with elevated triglyceride levels?






37. Name the antimicrobial agent whose major side effect is listed - Altered folate metabolism






38. What is the fastest - conducting fiber of the heart? Slowest conduction fiber in the heart?






39. How does cell diameter affect the conduction velocity of an action potential?






40. What foramen must be traversed for entry into the lesser peritoneal sac?






41. Where are the postganglionic neuron cell bodies - the CNS or the PNS?






42. What are the two side effects of opioids to which the user will not develop tolerance?






43. Which dimorphic fungus is endemic in the Ohio - Mississippi - Missouri - and Eastern Great Lakes - is found in soil with bird and bat feces - and is associated with infections in spelunkers and chicken coop cleaners?






44. What malignant neoplasm of the bone has a soap bubble appearance on radiograph?






45. How many carbons do androgens have?






46. Name the compartment of the lower extremity and the nerve based on its movements - Plantar flex the foot and evert the foot






47. What is the major pulmonary side effect of






48. Which sedative - hypnotic is contraindicated for patients taking warfarin?






49. What chronic systemic inflammatory disease commonly seen in women aged 20 to 50 is a progressive - symmetric arthritis affecting the hands - wrists - knees - and ankles that improves with increased activity?






50. What is the FiO2 of room air?







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