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USMLE Step 1 Prep

Subjects : health-sciences, usmle-step-1

Instructions:

Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can study here.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. On what chromosome is the adenomatous polyposis coli gene?
Lewy bodies
LTB4
Berry aneurysm
Chromosome 5q21

2. What pituitary hormone is inhibited during sleep?
T3 has a greater affinity for the nuclear receptor and therefore is considered the active form.
Urachus
Glycerol kinase
TSH. 5- HT and prolactin increase during sleep - and dopamine levels decrease during sleep.

3. Is a cause of asthma.
Alcoholics Anonymous
GERD
ater flows from a low - solute to high - solute concentrations.
The stapedius muscle

4. What are the three causes of transudate?
Medulla blastoma
CHF - cirrhosis - and nephrosis
Metaraminol (a1 - Beta1 )
Pimozide

5. What artery supplies the right atrium - right ventricle - sinoatrial and atrioventricular nodes?
In the first and second bronchi
Dendritic cells - macrophages - and thymic epithelial cells
Inhibited orgasm
Right coronary artery

6. What rare form of dementia is associated with personality changes and affects the frontal and temporal lobes?

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7. In which syndrome does a person present with intentionally produced physical ailments with the intent to assume the sick role?
Grasp proceeds release
Kupffer cells
M
LC4 - LD4 - and LE 4

8. What is the term for the total volume of air moved in and out of the respiratory system per minute?
C1 - C2 - or C4 deficiency
PALS (Parietolateral lymphocytic sheath)
90% as HCO3- - 5% as carbamino compounds - and 5% as dissolved CO2
Total ventilation (minute ventilation or minute volume)

9. What CNs are affected if there is a lesion in x Pontomedullary junction?
CN VI - VII - and VIII
Adjustment disorder. It is a diagnosis of exclusion (used if no other choice).
No. It is abnormal only if it interferes with normal sexual or occupational function.
Blastomyces dermatitidis

10. What are the three Beta - lactamase inhibitors?
Medial pontine syndrome
1. Clavulanic acid 2. Sulbactam 3. Tazobactam
SHIP: Shifting of the aorta - Hypertrophy of the right ventricle - Interventricular septal defect - Pulmonary stenosis
Nasal polyps - rhinitis - and aspirin hypersensitivity

11. What is the label given to an individual whose IQ is x 90 to 109
Both
>15 mm
Uric acid
Average

12. Is Dubin - Johnson or Rotor syndrome associated with black pigmentation of the liver?
Haemophilus influenzae type B
Osteoblast (Remember - blasts make - clasts take)
Fixed interval
Both are AR with conjugated hyperbilirubinemia - but Dubin - Johnson syndrome is differentiated from Rotor by the black pigmentation of the liver.

13. Which protein prevents internal binding of self proteins within an MHC class II cell?
3'end of the codon (third position) on mRNA and 5' end of the anticodon (first position) on tRNA.
Isoleucine - leucine - and valine
Ergotamines
Invariant chain

14. What are the three functions of surfactant?
Seminoma
Clearance
The courts. These are legal - not medical terms.
1. Increase compliance 2. Decrease surface tension 3. Decrease probability of pulmonary edema formation

15. Development of what T cell line follows low affinity for self - MHC class II Ags in the thymus?
Vaginismus; it is the female counterpart of premature ejaculation.
61 codons code for AAs and 3 codons (UAA - UGA - UAG) code for the termination of translation.
Nodes of Ranvier
CD4+T cells

16. What urinary metabolite is elevated in pheochromocytoma?
Primary follicle (in the white pulp)
The respiratory system
Thymidylate synthetase
Vanillylmandelic acid (VMA)

17. What type of fiber or fibers are carried in (answer motor - sensory - or both) x Dorsal root?
Sensory
Motor nucleus of CN V
Urogenital sinus
Iatrogenesis

18. What type of fiber or fibers are carried in (answer motor - sensory - or both) x Ventral root?
Motor
S phase
Prolyl and lysyl hydroxylases
Negative

19. Name the stages of sleep with these EEG patterns: x Sawtooth waves - random low voltage pattern
The conversion of tyrosine to dopamine in the cytoplasm
Moving objects - along with large bright objects with curves and complex designs.
REM
Transient ischemic attack

20. Do the duct or the acini cells of the pancreas secrete HCO3-?
Enkephalin
Duct cells secrete HCO3- - electrolytes - and water. The acini secrete the enzymes necessary for carbohydrate - nucleic acid - protein cleavage - and emulsification of fats.
Cryptococcus neoformans
Splenomegaly and anemia (with a high index of suspicion)

21. What happens to flow and pressure in capillaries with arteriolar dilation? Arteriolar constriction?
Capillary flow and pressure increase with arteriolar dilation and decrease with arteriolar constriction.
Type I hypersensitivity (anaphylactic)
Molluscum contagiosum
Cleft lip

22. What is the most common sexual assault?
Pedophilia
Conidia
Scleroderma
T and B- cells belong to the adaptive branch - whereas PMNs - NK cells - eosinophils - macrophages - and monocytes belong to the innate branch.

23. Name the insulin preparation based on the peak effect and duration of action - Peak - 0.5 to 3 hours; duration - 5 to 7 hours
Long - term memory is impaired in hippocampal lesions; it is spared in medial temporal lobe lesions.
Frontal eye field (Brodmann area 8)
Regular insulin
after abortion

24. Name the RNA subtype based on the following: x Carries AA to the ribosome for protein synthesis
Enterococcus (Streptococcus faecalis)
tRNA
Functionally they are part of the left lobe of the liver because they receive their blood supply from the left hepatic artery. Anatomically they are considered part of the right lobe of the liver.
PGI 2

25. What nerve is compromised in carpal tunnel syndrome?
Nodular sclerosis
CN III - IV - and VI
Hydroxyapatite
Median nerve

26. What AA is a precursor of the following substances? - Creatine
CSF
IgM
Glycine/arginine
Copper

27. Regarding the Lac operon - for What do the following genes code? - I gene
Lac repressor protein
Parkinson's disease (I can't underestimate all of the buzzwords in this question. Remember it.)
Good Samaritan Law. (Physicians are not required to stop and help.)
Chromosome 8 - 14

28. What bones make up the acetabulum?
Proencephalon diencephalon derivative
Echinococcus multilocularis
Pubis - ilium - and ischium
GABA and glutamic acid

29. Name the MCC - Walking pneumonia - seen in teens and military recruits
Succinate dehydrogenase
Four Ms and a U 1. Median 2. Medial antebrachial 3. Medial pectoral 4. Medial brachial cutaneus 5. Ulnar
Mycoplasma pneumoniae
Day 14

30. What operant conditioning therapy or modification is described as x Stopping the reinforcement that is leading to an undesired behavior?
Severe combined immunodeficiency disease
RSV
Extinction
Acute cystitis

31. Name the primary vesicle the following structures are derived from (proencephalon - mesencephalon - or rhombencephalon) - Neurohypophysis
Mumps and influenza virus
Estriol
Proencephalon diencephalon derivative
Osteosarcoma

32. Does the direct or indirect basal ganglia pathway result in a decreased level of cortical excitation?
Frameshift
Hemostasis
Although both pathways are associated with disinhibition - the indirect basal ganglia pathway is associated with a decreased level of cortical excitation.
Risk factors for breast cancer

33. What lymphoid organ has the following characteristics: outer and inner cortical areas - encapsulation - germinal centers - and high endothelial venules?
Postinfectious GN
2 - 4- Dinitrophenol
Propionibacterium acnes
Lymph nodes

34. What Brodmann area is associated with x Wernicke's area?
Bile salts are actively reabsorbed in the distal ileum.
Area 22 and occasionally 39 and 40
Bronchogenic carcinoma
Streptococcus pneumoniae

35. What are the pharmacologic effects seen sexually with x Serotonin?
Inhibited orgasm
Good Samaritan Law. (Physicians are not required to stop and help.)
Ethyl alcohol
Musculophrenic and superior epigastric arteries

36. What is the DOC for Beta- blocker - induced bronchospasms?
CN V1 - the occulomotor division of the trigeminal nerve - is the sensory component of the corneal reflex.
Ipratropium
Submandibular gland produces mainly serous and the sublingual gland produces mainly mucous secretions.
Brucella

37. What is the most common one? - Tumor in individuals exposed to asbestos
GH. The largest output of GH in a 24- hour period is during stage 4 sleep.
The odontoid process of C2
Acanthosis nigricans
Bronchogenic carcinoma

38. Which PG is associated with maintaining a PDA?
Stercobilin
PGE and intrauterine or neonatal asphyxia maintain patency of the ductus arteriosus. Indomethacin - ACh - and catecholamines promote closure of the ductus arteriosus.
Hydatidiform mole
The CD4 T cell; the APC is the first cell in the immune response.

39. What pH (acidotic or alkalotic) is needed for pepsinogen to pepsin conversion?
Acid is needed for the activation of pepsin and therefore needed for protein digestion.
Decreases
Glucokinase
The stomach

40. The faster the ___________ - the smaller the time of maximum concentration (Tmax) and the maximum concentration (Cmax).
Rate of absorption
Ketoconazole
Action potential
Transient hypogammaglobinemia of infancy; it usually resolves by age 16 to 30 months.

41. What lipoprotein is formed if an IDL particle acquires cholesterol from a HDL particle?
LDL
The tsetse fly
Megaloblasts
Diazepam is longest acting and midazolam is shortest acting.

42. Name the primary vesicle the following structures are derived from (proencephalon - mesencephalon - or rhombencephalon) - Thalamus
1. TTP 2. Lipoic acid 3. Coenzyme A from pantothenate 4. NAD(H) (from niacin or tryptophan) 5. FADH2 (from riboflavin)
Resorb CSF into the blood
Proencephalon
Bactericidal

43. What toxicities are caused by the following agents? - Halothane
Homicide. It is also the leading cause of death in black females aged 15 to 24.
IgA nephropathy
1. Cloxacillin 2. Oxacillin 3. Nafcillin 4. Dicloxacillin 5. Methicillin (CONDM)
Hepatitis - with or without necrosis

44. What is the rate - limiting enzyme on glycolysis?
Arch of the aorta
Phosphofructokinase -1 and costs 1 ATP
Orbitomedial frontal lobe
Listeria monocytogenes

45. What Ig is associated with Ag recognition receptor on the surface of mature B cells?
CN X (Remember - the vagus nerve supplies the parasympathetic information from the tip of the pharynx to the end of the midgut and all between.)
IgD; IgM is also correct.
Parkinson's disease
Itraconazole

46. What thyroid carcinoma secretes calcitonin and arises from the parafollicular C cells?
HBeAg
1. Glucagon 2. NADH 3. Acetyl CoA 4. ATP
Medullary carcinoma of the thyroid
Obstructive lung disorders. The opposite changes (where you see decrease exchange it for increase and vice versa) are seen in a restrictive pattern.

47.
prior to birthThe foramen ovale closes just...
Marijuana
Transient ischemic attack
MEN III (or IIb)

48. What three organs are responsible for peripheral conversion of T4 to T3?

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49. What is the second leading cause of cancer deaths in males? In females?

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50. What is the term for RBC fragments?
Proximal tubule
GERD
Jejunum (upper)
Schistocytes