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Test your basic knowledge |
USMLE Step 1 Prep
Start Test
Study First
Subjects
:
health-sciences
,
usmle-step-1
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What subset of adenocarcinoma arises from the terminal bronchioles and/or alveolar walls?
Outside the cell
CMV retinitis and HSV-2
Metformin
Bronchioloalveolar carcinoma
2. What is the most common lysosomal storage disorder?
Lung cancer
Loss of hypotonic fluid (alcohol - diabetes insipidus - dehydration)
Gaucher disease
Prolactinoma
3. Which class of antiarrhythmics are calcium channel blockers?
Left ventricle and auricle of left atrium
Adenocarcinoma of the cervix
Class IV
Mycobacterium marinum
4. Name the antidote - Copper
Escherichia coli
D- Penicillamine
Beta- Hydroxybutyrate
As the isotype is switched - the Ab specificity does not change because it does not affect the variable chains.
5. Name the antidote - Methyl alcohol
Mitral stenosis
Panacinar
50% - with 50% of them having the child
Ethyl alcohol
6. What happens to intrapleural pressure when the diaphragm is ontracted during inspiration?
Femoral hernias
Adjustment disorder. It is a diagnosis of exclusion (used if no other choice).
Intrapleural pressure decreases (becomes more negative).
Toxic dose for 50% of drug takers (median toxic dose)
7. What form of arthritis is associated with calcium pyrophosphate crystals?
CD40
Erythromycin
Pseudogout
Ulcerative colitis
8. What form of vasculitis involves the ascending arch and causes obliterative endarteritis of the vasa vasorum?
S1 nuclease
Syphilitic
In the ventral horn of the spinal cord. UMN cell bodies are in the precentral gyrus of the frontal lobe.
PCR
9. What acid form of H+ in the urine cannot be titrated?
Ego dystonic
Pantothenic acid
Primary spermatocyte
NH4+(ammonium)
10. What is the most common sexual assault?
Internal carotid artery and sympathetic plexus
Stable
HDL
Pedophilia
11. Name the type of necrosis - The most common form of necrosis; denatured and coagulated proteins in the cytoplasm
Acarbose
Serotonin
Coagulative necrosis
Cryptococcus neoformans
12. What is the term for the strength of the association between Ags and Abs?
Avidity. There is a positive correlation between valence numbers and avidity.
3 ATPs by oxidative phosphorylation
Squamous cell carcinoma
Mycoplasma
13. What is the term for black pigmentation of the colon associated with laxative abuse?
Duodenum (all but the first part) 2. Ascending Colon 3. Ureters 4. Pancreas 5. Supra renal glands (adrenals) 6. Descending colon 7. Aorta 8. Kidneys 9. Rectum 10. IVC D CUpS DAKRI is the mnemonic - everything else is covered with peritoneum
CN V
Fat necrosis
Melanosis coli
14. What type of mortality rate is defined as the number of deaths x From a specific cause per population?
Mycosis fungoides (cutaneous T- cell lymphoma)
Renal failure
1. Glucagon 2. NADH 3. Acetyl CoA 4. ATP
Cause - specific mortality rate
15. What fungus is characterized by India ink staining of the CSF that produces colorless cells with a halo on a black background?
Cryptococcus neoformans
Herpes II
Duodenal ulcer
F- Met - Peptides
16. Name the type of hypersensitivity reaction based on the following properties - Circulating Ab - Ag immune complexes deposited in the tissue result in neutrophil attraction and the release of lysosomal enzymes.
Nasal polyps - rhinitis - and aspirin hypersensitivity
Semicircular duct
Type III hypersensitivity (immune complex)
Because it is the largest vessel and has the highest velocity in systemic circulation
17. Name the four ventral mesentery derivatives.
1. The lesser omentum (consisting of the hepatoduodenal and hepatogastric ligaments) 2. Falciform ligament 3. Coronary ligament of the liver 4. Triangular ligament of the liver Liver is ventral; all other ligaments are dorsal mesentery derivatives.
Aldolase B deficiencies are treated by eliminating fructose from the diet.
Average
Blastomyces dermatitidis
18. Does Cushing syndrome or Cushing disease have elevated ACTH levels and cortisol suppression with dexamethasone?
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19. What is the most common cardiac tumor? In what chamber does it most commonly arise?
Tetracycline
env structural protein
Median nerve
90% of benign myxomas arise within the left atrium near the fossa ovalis.
20. What is the most common one? - Type of melanoma
Four high energy bonds - two from ATP in AA activation and two from GTP
Beta- Oxidation of fatty acids
Superficial spreading melanoma
Transport maximum (Tm) occurs when all function carriers are saturated and therefore is an index of the number of functioning carriers.
21. What is the most common one? Esophageal cancer in the United States
Osteomalacia. Osteoporosis has normal levels of calcium - phosphorus - and alkaline phosphatase.
Adenocarcinoma (because of Barrett esophagus)
Hydroxyproline (breakdown product of collagen)
(MA/CA) x 100 = IQ score - where MA = mental age and CA = chronological age
22. Is the carotid sinus sensitive to pressure or oxygen?
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23. In which syndrome does a person present with intentionally produced physical ailments with the intent to assume the sick role?
Decreases Remember - the carotid sinus reflex attempts to compensate by increasing both TPR and heart rate. -------------------------------------------------------------------------------
premature ejaculation
M
Patau syndrome (trisomy 13)
24. As what AAs do muscles send nitrogen to the liver?
Liver
N- Acetylcysteine
HPV serotypes 16 - 18 - 31 - and 33
Alanine and glutamine
25. Is cigarette smoking associated with transitional cell carcinoma of the bladder?
Yes. It is also a cause of cancers of the lung - esophagus - ureter - and kidney - just to Name a few.
Agents that decrease ACh function reduce tremors and rigidity - not bradykinesias.
Indirect hernia passes in the inguinal canal; a direct hernia passes directly through Hesselbach's triangle.
Taenia solium
26. Being college educated increases a man's risk of having...
G-6- PD deficiency
premature ejaculation
No - but it does interfere with performing complex tasks and decreases attention to detail. (Be careful post call!)
One - and it provides the energy for mechanical contraction.
27. What is the largest nucleus in the midbrain?
The substantia nigra is the largest nucleus in the midbrain. It contains melanin and uses GABA and dopamine as its neurotransmitters.
Graves disease
1. Protest 2. Despair 3. Detachment
Left eye anopsia (left nasal and temporal hemianopsia)
28. What is the drug of choice for treating a patient with hyperuricemia due to overproduction of uric acid?
Allopurinol
eIF-2 in the P site
The sensory component is through the superior laryngeal nerve - and the motor limb is via the recurrent laryngeal nerve.
Transient hypogammaglobinemia of infancy; it usually resolves by age 16 to 30 months.
29. What cell type of the body or fundus of the stomach secretes pepsinogen?
Rhabdomyoma
If positive - hypotonic urine (osmolarity <300 mOsm/L); if negative - hypertonic urine (osmolarity > 300 mOsm/L)>>
Pancreatic cancer
Chief cells
30. For what hormone do Leydig cells have receptors?
The alveoli at the apex are almost completely inflated prior to inflation - and although they are large - they receive low levels of alveolar ventilation.
LH
Labile
Ovulation
31. Name the valve abnormality based on the following criteria: x Back - filling into the left atrium during systole; increased v - wave - preload - left atrial volume - and left ventricular filling
Mitral insufficiency
Rhinoviruses for summer and fall; coronaviruses for winter and spring
Ganglioside
Crossover study
32. Below the ___________ - all the aponeurotic fibers run anterior to the rectus abdominis.
At the end of the PCT 25% of the original volume is left
Pyridoxine (B6) deficiency
The short arm of chromosome 6
Arcuate line
33. Match the chromosome and haploid number with the stage of sperm development - spermatid - spermatocyte (primary or secondary) - spermatogonia (type A or B): x 46/2n (divide mitotically)
Sympathetic chain ganglion
Edrophonium
Spermatogonia (type B)
Infrapatellar bursa
34. What is the most common one? - Organism associated with mastitis
The fastigial nucleus
Protein A
Staphylococcus aureus
Streptococcus viridans
35. When the ECF osmolarity increases - what happens to cell size?
Omphalocele and gastroschisis
The conversion of tyrosine to dopamine in the cytoplasm
Increase in ECF osmolarity means a in decrease in ICF osmolarity - so cells shrink.
1. Iliocostalis 2. Longissimus 3. Spinalis ('I Love Science' muscles)
36. What pineal hormone's release is inhibited by daylight and increased dramatically during sleep?
Histiocytosis X
These are the gross pathologic changes associated with Alzheimer's disease.
Western blot
Melatonin. It is a light - sensitive hormone that is associated with sleepiness.
37. There are no central ___ receptors.
Primary hypothyroidism (Low T4 has a decreased negative feedback loop - resulting in both the hypothalamus and the anterior pituitary gland to increase TRH and TSH release - respectively.)
t the end of the PCT 25% of Na+ - Cl - - K+ is left
Effective dose for 50% of drug takers (median effective dose)
O2
38. What is flat - circumscribed nonpalpable pigmented change up to 1 cm?
Factor XII for the intrinsic; factor VII for the extrinsic pathway
Macule (e.g. - a freckle)
Shiga toxin (enterohemorrhagic Escherichia coli produces Vero toxin - Which is quite similar to shiga toxin)
Knee
39. How is velocity related to the total cross - sectional area of a blood vessel?
Adenovirus
Transketolase and transaldolase. The reactions they catalyze are reversible.
Velocity is inversely related to cross - sectional area.
Protamine sulfate
40. Name the most common type or cause - Viral pneumonia leading to death
Hepatitis D
RSV
Plasma concentration and excretion rate
Chronic end - stage renal disease
41. What is the most common one? - Subtype of Hodgkin lymphoma
Cyproheptadine
Nodular sclerosis
MHC class I Ags (the endogenous pathway). This allows the body to eliminate tumor cells - virus - infected cells
Western blot
42. What is the most common one? - Acquired GI emergency of infancy
Necrotizing enterocolitis
Mumps
Under normal resting conditions no - but they are strongly stimulated when PO2 arterial levels decrease to 50 to 60 mm Hg - resulting in increased ventilatory drive.
Chromophobe adenoma
43. Activates the histidine operon.
Nissl substances; there is a great deal of RER in neuron cell bodies - indicating high protein synthesis.
Decreases Remember - the carotid sinus reflex attempts to compensate by increasing both TPR and heart rate.
Copper
Histidine
44. What is the term for the strength of the association between Ag and an Ab?
Puborectalis
GLUT 3 and 4
Affinity (one of each)
5 years old
45. What class of pharmaceuticals are inactive until they are metabolized to their active products?
H 1
Large intestine. Water is passively removed from the lumen.
Prodrugs
gp120
46. What is the drug of choice in treating a patient with hyperuricemia due to underexcretion of uric acid?
robenecid - a uricosuric agent
Amyotrophic lateral sclerosis (Lou Gehrig's disease) is a LMN lesion at the level of the lesion and UMN lesion below the level of the lesion.
Keratinocytes - the most numerous cells in the epidermis - carry melanin and produce keratin.
Major
47. What IL do T cells secrete to induce T- and B- cell division?
Eosin
Membranous glomerulonephritis
IL-2. T cells express IL-2 receptors on their surface to induce self - expression.
Liquefaction necrosis
48. Which subset of MEN syndrome is associated with the following? - Medullary carcinoma of the thyroid - pheochromocytoma - and mucocutaneous neuromas
MEN III (or IIb)
Stercobilin
Sertoli cell
Free hormone levels remain constant - and the bound hormone level changes with a decrease in binding hormones.
49. Anhedonia - lack of motivation - feelings of worthlessness - decreased sex drive - insomnia - and recurrent thoughts for at least 2 weeks - representing a change from previous level of function - describes what disorder?
CN V2
The small subunit (40S) binds first.
Sympathetic nervous system
Unipolar disorder (major depression)
50. Can advance directives be oral?
HBc Ab
Ligamentum venosum
Yes
Thiamine and folate
Sorry!:) No result found.
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