Test your basic knowledge |

USMLE Step 1 Prep

Subjects : health-sciences, usmle-step-1

Instructions:

Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can study here.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. What type of fiber or fibers are carried in (answer motor - sensory - or both) x Dorsal root?
Depression
With arteriolar constriction both the flow and pressure downstream decrease.
T and B- cells belong to the adaptive branch - whereas PMNs - NK cells - eosinophils - macrophages - and monocytes belong to the innate branch.
Sensory

2. What embryonic structure forms the adult male structure? - Gubernaculum testes
Gubernaculum
Increased REM sleep - decreased REM latency - and decreased stage 4 sleep - leading to early morning awakening
hypophosphatemia
Osteogenesis imperfecta

3. Name the most common type or cause - Neonatal bowel obstruction
Chromium (Cr)
It is rare with normal grief; however - it is relatively common in depression
Type I error (alpha error). (Remember it as saying something works when it doesn't.) The chance of a type I error occurring is the P value.
Hirschsprung disease

4. What type of crystals are associated with gout?
Monosodium urate crystals
Magnesium ammonium phosphate (struvite)
Superior rectus (CN III) (LR6 SO4)3
The placenta

5. What form of endocarditis do patients with SLE commonly encounter?
Pyruvate - acetyl CoA - and propionyl CoA carboxylase
Libman - Sacks endocarditis
Familial hypercholesterolemia
Achondroplasia

6. What renal calculus is associated with urea - splitting bacteria?
Magnesium ammonium phosphate (struvite)
Splitting of the first heart sound occurs during inspiration because of the increased output of the right ventricle - delaying the closure of the pulmonic valve.
The liver (in the mitochondria)
GLUT 4

7. What type of DNA library is made from the mRNA from a tissue expressing a particular gene?
after abortion
REM latency; normally it is about 90 minutes.
The stapedius muscle
cDNA libraries are derived from mRNA - are continuous - and contain no introns or regulatory elements.

8. What two vessels come together to form the external jugular vein?
1. Posterior auricular vein 2. Posterior division of the retromandibular vein
Wilson's disease (Remember chromosome 13 and hepatolenticular degeneration)
Ependymal cells
Male pseudo - intersexuality (hermaphrodite); these individuals are 46XY.

9. What is the major stimulus for cell division in chondroblasts?
LVEDV and LVEDP (left ventricular end - diastolic volume and end - diastolic pressure - respectively)
Flocculonodular lobe (one of my favorite words in all of medicine!)
IGF-1
Sarcoidosis

10. What determines the plasma level at steady state?
The rate of infusion
Carbamazepine
Vibrio parahaemolyticus
Stibogluconate

11. What do UMNs innervate?
Cortisol levels increase. Lymphocyte levels decrease in sleep - deprived individuals.
They innervate LMNs.
Primitive neuroectodermal tumors (i.e. - medulloblastomas and retinoblastomas)
Reverse transcription

12. Based on the following information - is the renal transplantation rejection acute - chronic - or hyperacute? - Weeks to months after transplantation; abrupt onset of oliguria and azotemia; seen as neutrophilic vasculitis and interstitial lymphocytes
Acute rejection
Glioblastoma multiforme
Dorsal prefrontal cortex
Melatonin. It is a light - sensitive hormone that is associated with sleepiness.

13. A 70-year - old man complains of urinary urgency - nocturia - hesitancy - postvoid dribbling - urinary retention - and a PSA result of 6.5 ng/mL. What is your diagnosis?
BPH. Although an argument can be made for prostatic cancer (you should expect a much higher PSA result) - these are buzzwords for BPH. Prostatic cancer is usually silent until late in the disease - when obstructive symptoms begin to occur.
Erythema marginatum
Priapism
Skeletal muscles

14. What vitamin is necessary for epithelial health?
Degenerates
Vitamin A is responsible for vision and epithelial health.
Ependymoma
Clearance

15. Multiple pregnancies - early age of intercourse - multiple sexual partners - OCP use - smoking - HIV - and STDs.
IgA - IgD - IgE - IgG - and IgM
Pulse pressure
TB meningitis
Risk factors for cervical cancer

16. What embryonic structure forms the adult male structure? - Epididymis - ductus deferens - seminal vesicle - and ejaculatory duct
Porcelain gallbladder
Mesonephric duct
Shine - Dalgarno sequence
CHF

17. Can a patient refuse life - saving treatment for religious reasons?

Warning: Invalid argument supplied for foreach() in /var/www/html/basicversity.com/show_quiz.php on line 183

18. Name the lung measurement based on the following descriptions: x Amount of air in the lungs after maximal expiration
Wilms tumor
Residual volume (RV)
Functions of hepatocytes
Phenylephrine

19. On the venous pressure curve - What do the following waves represent? - C wave?
Extracellular
Hypotonia (rag doll appearance)
Methylphenidate (Ritalin)
Ventricular contraction Atrial - Contraction - Venous

20. Name the cancer associated with the following chemical agents. (Some may have more than one answer.) x Polycyclic aromatic hydrocarbons
Bronchogenic carcinoma
The pH of CSF is 7.33 - acidotic.
Xanthine - hypoxanthine - theophylline - theobromine - caffeine - and uric acid are all purines.
Sickle cell disease

21. When do hCG concentrations peak in pregnancy?
In the first 3 months
2 NADPHs per acetyl CoA
Under normal resting conditions no - but they are strongly stimulated when PO2 arterial levels decrease to 50 to 60 mm Hg - resulting in increased ventilatory drive.
Roth spots

22. Name the cluster C personality disorder: x Orderly - inflexible - perfectionist; makes rules - lists - order; doesn't like change - has a poor sense of humor - and needs to keep a routine
Obsessive - compulsive
Haemophilus influenzae type B
Testosterone
Subdural hematoma is a rupture of the cerebral veins where they enter the superior sagittal sinus.

23. What are the three Beta - lactamase inhibitors?
1. Clavulanic acid 2. Sulbactam 3. Tazobactam
RNA polymerase III
Vancomycin
Cancer of the lung - stomach - colon - and breast

24. What is the drug of choice for treating Tourette syndrome?
Lentigo maligna melanoma
Subacute bacterial endocarditis
Emphysematous bleb
Pimozide

25. Why is the clearance of creatinine always slightly greater than the clearance of inulin and GFR?
In the ventral horn of the spinal cord. UMN cell bodies are in the precentral gyrus of the frontal lobe.
Because creatinine is filtered and a small amount is secreted
Ethyl alcohol
apo A-1

26. Which calcium channel blocker is used to treat subarachnoid hemorrhages by preventing posthemorrhagic vasospasms?
Alveolar macrophages
HMG CoA reductase
Central/neurogenic diabetes insipidus; in the nephrogenic form there is sufficient ADH available - but the renal collecting ducts are impermeable to its actions.
Nimodipine

27. Name the compartment of the mediastinum associated with the following thoracic structures: Vagus nerve
Bunyavirus
Posterior
Conjugated (direct) hyperbilirubinemia
Water

28. How can a deficiency in adenosine deaminase be a bone marrow suppressor?
Maxillary artery
Yes
It causes a buildup of dATP - which inhibits ribonucleotide reductase and leads to a decrease in deoxynucleoside triphosphate - a precursor of DNA - resulting in overall bone marrow suppression.
GH deficiency

29. What three lung measurements must be calculated because they cannot be measured by simple spirometry?
Glomerular capillary pressure (increased glomerular capillary pressure - increased GFR and vice versa)
TLC - FRC - and RV have to be calculated. (Remember - any volume that has RV as a component has be calculated.)
Coxsackie A
Sideroblastic anemia

30. What is the formula to calculate IQ?
Aspartate transcarbamylase
(MA/CA) x 100 = IQ score - where MA = mental age and CA = chronological age
Sadism
IgA nephropathy (Berger disease)

31. What vitamin is a component of the coenzyme thiamine pyrophosphate (TPP)?
1. Benefits of the procedure 2. Purpose of the procedure 3. Risks of the procedure 4. The nature of the procedure (what you are doing) 5. The alternative to this procedure and its availability (Don't forget the last one; this is where physicians get
Conn syndrome (primary hyperaldosteronism)
Thymine (B1)
Goodpasture disease

32. What is the size of a positive PPD test for the following? (Reactive) x Posttransplantation patient taking immunosuppressive agents
Pregnancy
>5 mm
hCG can be detected in the blood by day 8 and in the urine by day 10.
Schistosoma have separate males and females.

33. Name the most common type or cause - Infection in a patient on a ventilator
Posterior interventricular artery
1. Bunyavirus 2. Orthomyxovirus 3. Arenavirus 4. Reovirus Remember BOAR
CN V2
Pseudomonas aeruginosa

34. What test uses p24 protein when diagnosing HIV?
Breast cancer
ELISA test
A low - resistance system is formed by resistors added in parallel.
C5a

35. What leukemia affects a 4-year - old child with 3 months of fever - fatigue - generalized lymphadenopathy - CNS involvement - hepatosplenomegaly - bleeding - and platelet count below 100 - 000?
Because incidence is defined as new events; treatment does not decrease the number of new events. It does decrease the number of individuals with the event (prevalence would decrease).
Amantadine
ll
HMG CoA reductase

36. What area of the hypothalamus is responsible for recognizing a decrease in body temperature and mediates the response to conserve heat?

Warning: Invalid argument supplied for foreach() in /var/www/html/basicversity.com/show_quiz.php on line 183

37. What enzyme is inhibited by sulfonamides?
Prevalence rate
Leiomyoma
Dihydropteroate synthetase
Metronidazole

38. Name the hormone
Ratio scale
Glucagon
In children - the fourth ventricle; in adults - the lateral ventricle or spinal cord
Cardiac muscle

39. Hereditary angioneurotic edema (AD) produces local edema in organs (e.g. - GI - skin - respiratory tract). What enzyme deficiency causes increased capillary permeability due to a release of vasoactive peptides?
Second M PITS for pharyngeal pouch derivatives
Acting out
Radial nerve
C1 esterase inhibitor (C1INH)

40. What is the term for a delay in the onset of normal IgG synthesis seen in the fifth to sixth month of life?
Liver - kidney - and GI epithelium
The popliteal artery - the deepest structure in the popliteal fossa - risks injury in a supracondylar fracture of the femur.
An increase in serum glucose levels
Transient hypogammaglobinemia of infancy; it usually resolves by age 16 to 30 months.

41. What type of scheduled reinforcement states that after a desired response - the reinforcement is given x After a set number of responses?
Leydig cell tumor
Metaproterenol and albuterol
Fixed ratio (rewards set behaviors)
Kupffer cells

42. What is the term for involuntary constriction of the outer third of the vagina to prevent penile penetration?
Streptococcus agalactiae
Autosomal recessive
Vaginismus; it is the female counterpart of premature ejaculation.
In the first 3 months

43. What enzyme is needed to activate the following reactions? - Procarboxypeptidase to carboxypeptidase
Trypsin
Cori cycle
Urinary 17- OH steroids
RNA polymerase II

44. What protein allows Mycoplasma to attach to the respiratory epithelium?
Proencephalon
1. Sartorius 2. Gracilis 3. Semitendinous
Chronic rejection
P1 protein

45. What phase of the female cycle occurs during days 1 to 15?
Accidents
Follicular phase
Two Lateral foramina of Luschka and 1 Medial foramen of Monroe (L for Lateral and M for Medial)
Primary hypoparathyroidism

46. Do the following structures pick up stain from hematoxylin or eosin? - Collagen
Eosin
Squamous cell carcinoma
Pseudomonas aeruginosa
Membrane conductance (think conductance = channels open)

47. In which syndrome does a person present with intentionally produced physical ailments with the intent to assume the sick role?
M
As the isotype is switched - the Ab specificity does not change because it does not affect the variable chains.
The alveoli at the apex are almost completely inflated prior to inflation - and although they are large - they receive low levels of alveolar ventilation.
Churg - Strauss syndrome

48. What are the three causes of normochromic normocytic anemia with a normal MCV and a low reticulocyte count?
Relative risk and/or attributable risk. (Cohort studies deal with incidence.)
Flutamide
Breast cancer
Marrow failure - cancer - and leukemia

49. Name the type of regeneration (i.e. - labile - stable - or permanent) based on the following examples - Liver
Ureaplasma urealyticum
Stable
Wernicke's aphasia
Ungated channels

50. In the alveoli - what cell type is x for gas exchange?
Superior
The surface of the medulla
Turner syndrome
Type I pneumocytes