Test your basic knowledge |

USMLE Step 1 Prep

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What is the term for the sign revealed when a psoriatic scale is removed and pinpoint bleeding occurs?






2. What enzyme of the TCA cycle catalyzes the substrate level phosphorylation?






3. Which muscles of the eye are under parasympathetic control?






4. What is the rate - limiting step of the following? - Ketogenolysis






5. What happens to intrapleural pressure when the diaphragm is ontracted during inspiration?






6. What organism is associated with the following types of diarrhea? Bloody diarrhea associated with hamburger ingestion






7. What pancreatic islet cell secretes glucagons?






8. Takes place in both the cytoplasm and the mitochondria.






9. What enzyme of heme synthesis is deficient in the autosomal dominant disorder acute intermittent porphyria?






10. Name the most common type - Phobia






11. What are the four types of signaling mechanisms?






12. What bilateral AR disorder seen in infancy as progressive renal failure has multiple small cysts at right angles to the cortical surface?






13. What is the drug of choice for filariasis and onchocerciasis?






14. What vitamin deficiency can result in high - output cardiac failure?






15. Craniopharyngiomas are remnants of what?

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16. Name the cancer associated with the following tumor markers. (Some may have more than one answer.) x CA-19.9 and CEA






17. Testing of a drug in a small group of volunteers without the disease is a component of which phase of clinical drug testing?






18. Would a G- C or an A- T rich dsDNA sequence have a higher melting point? Why?






19. What pyrimidine base is found x In both DNA and RNA?






20. Which hepatitis B serology markers






21. What presynaptic receptor does NE use to terminate further neurotransmitter release?






22. What disease is X- linked recessive - is associated with eczema thrombocytopenia and an increased chance of developing recurrent infections - involves a decrease in serum IgM and in the T cell - dependent paracortical areas of the lymph nodes - and m






23. What epidermal layer's function is to release lipids to act as a sealant?






24. What form of renal tubular reabsorption is characterized by low back leaks - high affinity of a substance - and easy saturation? It is surmised that the entire filtered load is reabsorbed until the carriers are saturated - and then the rest is excret






25. What is the name of the postganglionic parasympathetic ganglion that innervates x The submandibular and sublingual glands?






26. What is the term when the brachial artery is compressed - resulting in ischemic contracture of the hand?

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27. Name the type of graft described by these transplants: Between genetically identical individuals






28. What are the first signs of overdose from phenobarbitals?






29. Name the product or products of arachidonic acid: x Vasodilation and inhibition of platelet aggregation produced by vascular endothelium






30. What AD syndrome involves 1000 or more edematous polyps - most commonly affects the colorectal area - and is associated with chromosome 5q21?






31. What antiviral agent is used to treat RSV - influenza A and B - Lassa fever - and hantavirus and as an adjunct to IFN- in hepatitis C?






32. What type of bias is it when the information is distorted because of the way it is gathered?






33. With What thoracic vertebra or vertebrae does rib 7 articulate?






34. Name the thalamic nucleus based on its input and output - Input from the optic tract; output projects to the primary visual cortex of the occipital lobe






35. Name the antidote - AChE inhibitors






36. What is the most common one? - Benign breast tumor in females less than 35 years old






37. What is the major muscle used in the relaxed state of expiration?






38. What is the name of the force that develops in the wall of the lungs as they expand?






39. What chromosome is mutant in patients with cystic fibrosis?






40. What operant conditioning therapy or modification is described as x Providing the person with information regarding his or her internal responses to stimuli with methods of controlling them?






41. If a virus has positive sense RNA - can it be used as mRNA or is a template needed?






42. What are the five pieces of information considered necessary for fully informed consent?

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43. Familial hypercholesteremia is due to a mutation in the LDL receptor gene. What chromosome carries it?






44. What three circumstances allow a child to be committed to institutional care?

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45. Name the most common type or cause - Cirrhosis in the United States






46. Name the cancer associated with the following oncogenes. (Some may have more than one answer) x CDK4






47. What enzyme is inhibited by trimethoprim?






48. Is cigarette smoking associated with transitional cell carcinoma of the bladder?






49. Blood and its vessels form During What embryonic week?






50. What DNA virus is associated with heterophile - negative mononucleosis?