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USMLE Step 1 Prep

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. If the pH is low with increased CO2 levels and decreased HCO3- levels - What is the acid - base disturbance?






2. What three substrates control the enzyme PEPCK for the conversion of oxaloacetate (OAA) to pyruvate in the cytoplasm?






3. Name the area of the cerebral cortex affected by the description of the effects - symptoms - and results of the lesion - Euphoria - delusions - thought disorders - Wernicke's aphasia - auditory hallucinations (Hint: the lesion is in the left hemisph






4. Name the type of hypersensitivity reaction based on the following properties - IgE- mediated release of chemical mediators from basophils and mast cells; need prior exposure to Ag in the past; eosinophils amplify and continue reaction; can be system






5. What part of a neuron receives information?






6. Name the compartment of the mediastinum associated with the following thoracic structures: Ascending aorta






7. With what disease do you see IgA deposits in small vessels of the skin and the kidneys?






8. How many pairs of spinal nerves exit from the spinal cord?






9. Name the antimicrobial agent whose major side effect is listed - Auditory toxicity






10. What benign cardiac tumor is associated with tuberous sclerosis?






11. In regards to solute concentration - how does water flow?






12. Which two tetracyclines have the highest plasma binding?






13. Which dimorphic fungus is endemic in the Ohio - Mississippi - Missouri - and Eastern Great Lakes - is found in soil with bird and bat feces - and is associated with infections in spelunkers and chicken coop cleaners?






14. Which carcinoma






15. In what rare lung malignancy have 90% of patients had an occupational exposure to asbestos?






16. What are the five branches of the superior mesenteric artery?






17. What enzyme is deficient in alkaptonuria?






18. Megaloblastic anemia and thrombocytopenia are signs of what vitamin deficiency?






19. What substance is secreted by parietal glands and is required for life?






20. Are hydrolysis - oxidation - and reduction phase I or II biotransformations?






21. What somatoform disorder is described as x Unrealistic negative opinion of personal appearance - seeing self as ugly?






22. Name the most common cause - Blindness in the United States






23. What organism is associated with the following types of diarrhea? Bloody diarrhea associated with hamburger ingestion






24. What sensory system is affected in the late spinal cord manifestation of syphilis?






25. Name the cancer associated with the following chemical agents. (Some may have more than one answer.) x Vinyl chloride






26. If inserting a needle to perform a pleural tap or insertion of a chest tube - do you use the inferior or the superior border of a rib as your landmark? Why?






27. What AA is substituted for glutamic acid at position 6 on the Beta - chain in patients with sickle cell anemia?






28. What is the most common one? - Thyroid cancer






29. Name the GLUT transporter based on the following: x Found in liver and pancreatic Beta- cells






30. Name the ocular lesion; be specific - Right calcarine cortex lesion






31. Fact without feeling (la belle indiff






32. What is the effect of T3 on heart rate and cardiac output?






33. What AA is a precursor of the following substances? - NAD






34. Which cestode infection results in alveolar hydatid cyst disease?






35. Name the stages of sleep with these EEG patterns: x Disappearance of alpha waves - appearance of theta waves






36. What is the term for the day after the LH surge in the female cycle?






37. What is the term for the appearance of the kidney in malignant hypertension (it has petechiae on its surface)?






38. What is the term for dilated veins within the spermatic cord?






39. What leukemia affects a 4-year - old child with 3 months of fever - fatigue - generalized lymphadenopathy - CNS involvement - hepatosplenomegaly - bleeding - and platelet count below 100 - 000?






40. What encapsulated gram - negative - lactose - fermenting rod is associated with pneumonia in patients with alcoholism - diabetes - and chronic lung disease?






41. Where is renin produced?






42. What is the most common lysosomal storage disorder?






43. Name the area of the cerebral cortex affected by the description of the effects - symptoms - and results of the lesion - Denial of illness - hemineglect - construction apraxia (can't arrange matchsticks)






44. Name the 10 retroperitoneal organs.






45. Dopamine antagonists are...






46. What parasite found in raw fish can produce vitamin B12 deficiency?






47. What are the three polymorphonuclear leukocytes? Be specific.






48. Which tetracycline is used in the treatment of SIADH?






49. What breast malignancy has tumor cells with a halo surrounding the nucleus and is an ulceration of the nipple and areola with crusting - fissuring - and oozing?






50. What are the two ways that nitrogen can enter into the urea cycle?