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USMLE Step 1 Prep

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Which muscarinic receptor uses a decrease in adenyl cyclase as its second messenger?






2. What are the three naked RNA viruses?






3. In prokaryotes - What is the term for a set of structural genes that code for a select group of proteins and the regulatory elements required for the expression of such gene?






4. Name the thalamic nucleus based on its input and output - Input from inferior colliculus; output to primary auditory cortex






5. How does L- tryptophan affect sleep?






6. What form of poisoning is associated with bitter almond - scented breath?






7. What cells of the epidermis - derived from the neural crest - act as mechanoreceptors?

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8. What type of membrane channel opens in response to depolarization?






9. What two viruses are associated with Reye's syndrome?






10. What purine base is contained in inosine monophosphate?






11. What CNs are responsible for the sensor and motor components of the light reflex?






12. Name the cancer associated with the following oncogenes. (Some may have more than one answer) x CDK4






13. What is the term for the load on a muscle in the relaxed state?






14. What happens to plasma concentration of a drug if there is a large volume of distribution?






15. WBC casts in the urine






16. Where is the cupola of the lung in relation to the subclavian artery and vein?






17. Name the AD disease associated with chromosome 15 in which the patient has long extremities - lax joints - pigeon chest - and posterior mitral leaflet prolapse and is prone to developing dissecting aortic aneurysm.






18. What antifungal agent is activated by fungal cytosine deaminase to form 5- FU?






19. As what AAs do muscles send nitrogen to the liver?






20. Are reabsorbed in the gallbladder.






21. What are the three carboxylase enzymes that require biotin?






22. Which hepatitis B serology markers






23. What complement factor deficiency leads to x Leukocyte adhesion deficiency with poor opsonization?






24. What area of the brain acts as the center for ipsilateral horizontal gaze?






25. What is the term for processing an APC's pinocytosed material by fusing with a lysosomal granule and cleaving the Ag into peptide fragments?






26. Are the following responses associated with histamines H1 or H2 receptor activation? - Pain and pruritus






27. What AR disease involves a defect in AA 508 on chromosome 7 - causing a defect in Cl - transportation that leads to recurrent pulmonary infections and an increase in viscid mucoid secretions along with pancreatic insufficiencies?






28. What drug - if given during pregnancy - would cause the uterus to exhibit signs of progesterone withdrawal and induce an abortion?






29. What syndrome is described by a lesion in the angular gyrus (area 39) resulting in alexia - agraphia - acalculia - finger agnosia - and right - left disorientation?

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30. What body fluid preferentially breaks down esters?






31. What is the function of the basal ganglia?






32. Name the lung measurement based on the following descriptions: x Maximal volume that can be expired after maximal inspiration






33. Name the MCC - Pneumonia in a patient with atypical bird exposure and hepatitis






34. Based on operant conditioning - What type of reinforcement is described when x Removing a stimulus reinforces a behavior?






35. Which protein prevents internal binding of self proteins within an MHC class II cell?






36. What somatomedin serves as a 24- hour marker of GH secretion?






37. What is the term for a RBC that has a peripheral rim of Hgb with a dark central Hgb - containing area?






38. From what pharyngeal groove is the external auditory meatus derived?






39. What variant of polyarteritis nodosa is associated with bronchial asthma - granulomas - and eosinophilia?






40. What chronic inflammatory WBC is associated with IgE- mediated allergic reactions and parasitic infections?






41. Unconsciously forgetting(forgetting that you forgot something!)






42. With what stage of sleep is enuresis associated?






43. Name the correct artery - The right recurrent laryngeal nerve passes around it.






44. What splanchnic carries preganglionic parasympathetic fibers that innervate the hindgut and the pelvic viscera?






45. Which three organisms cause heterophilic negative mononucleosis?






46. At what vertebral levels does the aortic arch begin and end?






47. What are the three surrogate criteria?

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48. What type of spore is defined as an asexual budding daughter yeast cell?






49. What nerve is associated with the following functions? - Flex the shoulder - flex the elbow - and supinate the elbow






50. What is the DOC for the following protozoal infections? - Pneumocystis carinii pneumonia