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USMLE Step 1 Prep

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What topoisomerase makes ssDNA cuts - requires no ATP - relaxes supercoils - and acts as the swivel in front of the replication fork?






2. What is the most common one? - Cancer of the esophagus in the world






3. What organism is associated with the following types of diarrhea? Rice water stools






4. What adrenal enzyme deficiency can be summed up as a mineralocorticoid deficiency - glucocorticoid deficiency - and an excess of adrenal androgens?






5. Is irreversible






6. What component of the corneal reflex is lost in a CN VII deficit?






7. With which CN are preganglionic parasympathetic axons arising from the Edinger - Westphal nucleus associated?






8. What happens to prevalence as incidence increases?






9. The 'tea - and - toast' diet is classically associated with what cause of megaloblastic anemia?






10. What syndrome is characterized by embryologic failure of the third and fourth pharyngeal pouches resulting in hypocalcemia - tetany - and T- cell deficiency?






11. What parasympathetic nucleus is found on the floor of the fourth ventricle and supplies preganglionic fibers innervating the terminal ganglias of the thorax - foregut - and midgut?






12. What lower extremity nerve is described by the following motor loss? - Loss of knee extension - weakened hip flexion






13. Where is ADH synthesized?






14. What obligate extracellular fungus is silver stain - positive and is associated with pneumonia in patients with AIDS?






15. What disease is associated with the HLA- DR2 and HLA- DR3 alleles






16. What is the only enzyme in the body that uses N-5- methyl folate?






17. Which organism causes multiple infections by antigen switching?






18. Name these mature defense mechanisms: x Converting an unacceptable impulse to a socially acceptable form (Hint: it is the most mature of all defense mechanisms)






19. What syndrome is characterized by dynein arm abnormality resulting in chronic sinusitis - recurrent pulmonary infections - and infertility?

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20. What are the three carboxylase enzymes that require biotin?






21. What malignant bone tumor is characterized by Codman triangle (periosteal elevation) on radiograph?






22. Is excretion greater than or less than filtration for net secretion to occur?






23. Name the primary vesicle the following structures are derived from (proencephalon - mesencephalon - or rhombencephalon) - Midbrain






24. What mineral deficiency in children is associated with poor growth and impaired sexual development?






25. What autoimmune syndrome is characterized by keratoconjunctivitis - corneal ulcers - xerostomia - and an increased risk of high - grade B- cell lymphomas? What two Ab tests are used in making the diagnosis?






26. Name the hepatitis virus based on the following information - Enveloped DNA hepadnavirus






27. What components of the coagulation cascade are affected by estrogen?






28. The opening of what valve indicates the termination of isovolumetric relaxation phase of the cardiac cycle?






29. By What age should children be able to draw the following figures? - Cross






30. What percentage of cardiac output flows through the pulmonary circuit?






31. What are the two essential fatty acids?






32. Where do the primordial germ cells arise?






33. What viral infection is associated with black vomit?






34. Which type of cerebral herniation is associated with CN III palsy?






35. Name the associated chromosome - Albinism






36. What is the term for the same results achieved again on testing a subject a second or third time?






37. What cancer of the male genitourinary system is associated with osteoblastic bony metastasis?






38. What is the most common one? - Proliferative abnormality of an internal organ






39. In a skeletal muscle fiber - the interior of the T- tubule is...






40. What is the most common one? - Cardiac tumor of infancy






41. What normochromic - normocytic AD anemia has splenomegaly and increased osmotic fragility?






42. What bactericidal agent is the DOC for MRSA - enterococci - and Clostridium difficile?






43. What is the term for the strength of the association between Ags and Abs?






44. Name the most common type or cause - Panhypopituitarism






45. What diseases are associated with the HLA- B27 allele

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46. What direction does the primitive gut rotate? What is its axis of rotation?






47. Which hepatitis B serology markers






48. What form of bilirubin can cross the blood - brain barrier?






49. What is the function of the basal ganglia?






50. How does ceasation of barbiturate use affect sleep?