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USMLE Step 1 Prep

  • Answer 50 questions in 15 minutes.
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  • Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Familial hypercholesteremia is due to a mutation in the LDL receptor gene. What chromosome carries it?

2. Name the antidote - Arsenic

3. What classical conditioning therapy or modification is described as x Triage of a hierarchy of fears (from least to most) - then teaching muscle relaxation techniques in the presence of those fears until the subject is not afraid anymore?

4. What is the term for nonneoplastic abnormal proliferation of cell size - shape - and cellular organization?

5. What papillae are responsible for sweet taste?

6. What is the name of the spinal cord passing within the subarachnoid space and forming the spinal nerves that exit the lumbar and sacral foramina?

7. What diseases are associated with the HLA- DR3 allele

8. What nerve is associated with the following functions? - Flex the wrist and digits - pronate the wrist and the LOAF (Lumbricales - Opponens pollicis - Abductor pollicis brevis - Flexor pollicis brevis) muscles of the hand

9. What subunit of hCG is used to detect whether a patient is pregnant?

10. What epidermal layer's function is to release lipids to act as a sealant?

11. What is the relationship between chance of error and x Sample size?

12. What is the term for the strength of the association between Ags and Abs?

13. Name the most common type or cause - Liver transplantation in adults

14. Which IV agent has the lowest incidence of postoperative emesis and has the fastest rate of recovery?

15. What AA is a precursor of the following substances? - Creatine

16. What is the most common one? - Site for carcinoid tumors

17. What class of pharmaceuticals are inactive until they are metabolized to their active products?

18. What is the longest and most convoluted segment of the nephron?

19. Name the form of spina bifida - Meninges project through a vertebral defect

20. What statistical test checks to see whether the groups are different by comparing the means of two groups from a single nominal variable?

21. What hormone is required for 1 - 25- dihydroxy- vitamin D (1 - 25- diOH- D) to have bone resorbing effects?

22. Describe What type of fluid is either gained or lost with the following changes in body hydration for the ECF volume - ICF volume - and body osmolarity - respectively: x ECF - decrease; ICF - no change; body - no change

23. What components of the coagulation cascade are affected by estrogen?

24. Why is spermatogenesis decreased with anabolic steroid therapy?

25. Name the compartment of the mediastinum associated with the following thoracic structures: Pulmonary artery and veins

26. What mushroom poisoning is associated with fulminant hepatitis with extensive liver necrosis?

27. Which medication requires an acidic gastric pH for activation to form a protective gel - like coating over ulcers and GI epithelium?

28. From What aortic arch are the following structures derived?

29. In the alveoli - what cell type is x responsible for producing surfactant?

30. What antifungal agent is used to treat dermatophyte infections by inhibiting squalene epoxidase?

31. What stage of sleep is associated with somnambulism?

32. What disease is seen in children younger than 5 years of age and is characterized by X- linked recessive cardiac myopathies - calf pseudohypertrophy - lordosis - protuberant belly - an increase then a decrease in CPK - and death commonly in the secon

33. In which syndrome does a person present with intentionally produced physical ailments with the intent to assume the sick role?

34. What happens to the following during skeletal muscle contraction? - Sarcomere

35. Which subset of MEN syndrome is associated with the following? - Medullary carcinoma of the thyroid - pheochromocytoma - and parathyroid adenomas (or hyperplasia)

36. What muscle type is characterized by low ATPase activity - aerobic metabolism - myoglobin - association with endurance - and small muscle mass?

37. With What three enzymes is thiamin pyrophosphate (TPP) associated?

38. There are no persistent infections with...

39. What is the respiratory compensation mechanism for metabolic alkalosis?

40. What nerve lesion presents with ape or simian hand as its sign?

41. What selective Cox-2 inhibitor should be avoided in patients with a history of sulfonamide allergy?

42. Which carcinoma

43. What prostaglandin is associated with maintaining patency of the ductus arteriosus?

44. What component of an ECG is associated with the following? - Atrial depolarization

45. Name the MCC of death - In patients with cystic fibrosis

46. Name the B- cell CD marker: x Used clinically to count B cells in blood

47. What family do the following viruses belong to? - California encephalitis

48. What is the largest organ in the body?

49. What type of fiber or fibers are carried in (answer motor - sensory - or both) x Spinal nerve?

50. What structure or structures cross the diaphragm at x T8 level?