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USMLE Step 1 Prep

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What day of the menstrual cycle does ovulation take place?






2. What antiviral agent is used to treat RSV - influenza A and B - Lassa fever - and hantavirus and as an adjunct to IFN- in hepatitis C?






3. Russell bodies






4. What subtype of schizophrenia is characterized by x Stuporous mute echopraxia and automatic obedience - waxy flexibility with rigidity of posture?






5. What is the term for pus in the pleural space?






6. What form of bilirubin can cross the blood - brain barrier?






7. Is derived from the ventral wall of the foregut.






8. What syndrome is characterized by embryologic failure of the third and fourth pharyngeal pouches resulting in hypocalcemia - tetany - and T- cell deficiency?






9. What enzyme of the purine salvage pathway is deficient in the following? - SCID






10. What vessel is lacerated in an epidural hematoma?






11. Describe the loss for each of the following in a hemisection of the spinal cord. (Brown - S






12. Are the following responses associated with histamines H1 or H2 receptor activation? - SA nodal activity






13. What is the term for diffusion of water across a semipermeable or selectively permeable membrane?






14. How does L- tryptophan affect sleep?






15. In the water deprivation test - does a patient with reduced urine flow have primary polydipsia or diabetes insipidus?






16. What three complement fragments are also anaphylatoxins?






17. What pathophysiologic disorder is characterized by the following changes in cortisol and ACTH? - Cortisol decreased - ACTH decreased






18. Name these anxiety defense mechanisms: x Separating oneself from the experience. The facts are accepted but the form is changed for protection.






19. Streaky ovaries






20. What are the three main components of amyloid?






21. What are the two broad - spectrum penicillins?






22. Require NaCl in its growth medium.






23. In the systemic circulation - what blood vessels have the largest pressure drop? Smallest pressure drop?






24. What operant conditioning therapy or modification is described as x Reinforcing successive attempts that lead to the desired goal (gradual improvement)?






25. Which anticonvulsant is used in the treatment of bipolar disorder and neuropathic pain?






26. What female follicular cell is under LH stimulation and produces androgens from cholesterol?






27. What attaches the cusps of the valves to the papillary muscles in the heart?






28. Name the lung measurement based on the following descriptions: x Additional volume that can be expired after normal expiration






29. Do genomic or cDNA libraries contain introns - exons - promoters - enhancers - and are they fragmented?






30. When a drug is administered orally and enters into portal circulation - it undergoes hepatic metabolism. What is the name of this effect?






31. What three substances stimulate glycogenolysis?






32. Are the following major or minor Jones criteria of rheumatic fever? - Elevated acute phase reactants (e.g. - ESR)






33. What embryonic structure forms the adult male structure? - Gubernaculum testes






34. Fluoroquinolones are...






35. In what disease do you see horseshoe kidneys - rockerbottom feet - low - set ears - micrognathia - and mental retardation?






36. What happens to the Ab specificity when class switching occurs in mature B cells?






37. What is the name for the following RBC indices? - Average volume of a RBC






38. As what compound do the carbons for fatty acid synthesis leave the mitochondria?






39. What class of antimicrobial agents should be avoided in patients with a history of GPDH deficiency?






40. Hereditary angioneurotic edema (AD) produces local edema in organs (e.g. - GI - skin - respiratory tract). What enzyme deficiency causes increased capillary permeability due to a release of vasoactive peptides?






41. What is the only NSAID that causes irreversible inhibition of the cyclooxygenase pathway?






42. Patients with sickle cell anemia are at increased risk for infection From what type of organisms?






43. What three cephalosporins are eliminated via biliary mechanisms?






44. What are five clinical signs of portal HTN?






45. Name the end product or products: x Fatty acid synthesis






46. What cells of the adrenal gland are neural crest derivatives?






47. Name the primary vesicle the following structures are derived from (proencephalon - mesencephalon - or rhombencephalon) - Thalamus






48. What is the best measure of total body vitamin D if you suspect a deficiency?






49. Name the type of regeneration (i.e. - labile - stable - or permanent) based on the following examples - Hematopoietic cells






50. What is the term for the potential difference across a cell membrane?