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USMLE Step 1 Prep

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. How many pairs of spinal nerves exit from the spinal cord?






2. What is the leading cause of primary hyperparathyroidism?






3. With What three enzymes is thiamin pyrophosphate (TPP) associated?






4. What is the amount in liters and percent body weight for the following compartments? - Vascular fluid






5. What primary acid - base disturbance is cause by a decrease in alveolar ventilation (increasing CO2 levels) resulting in the reaction shifting to the right and increasing H+ and HCO3- levels?






6. What bacterium is responsible for woolsorter's disease?






7. Name the cancer associated with the following chemical agents. (Some may have more than one answer.) x Vinyl chloride






8. What virus is associated with Guarnieri bodies?






9. Name the type of regeneration (i.e. - labile - stable - or permanent) based on the following examples - Skeletal muscle






10. What substrate is built up in Niemann - Pick disease?






11. What is the statistical term for the proportion of truly nondiseased persons in the screened population who are identified as nondiseased?






12. What are known as jumping genes?






13. What subset of adenocarcinoma arises from the terminal bronchioles and/or alveolar walls?






14. What regulates the rate of ketone body formation?






15. What structure of the knee is described thus? - Prevents anterior displacement and has lateral - to - medial attachment on the tibia






16. At what stage of cognitive development (according to Piaget) do children x Have abstract thinking?






17. What type of hepatitis has the highest mortality rate among pregnant women?






18. Name the antidote - AChE inhibitors






19. What is the period between falling asleep and REM sleep called?






20. What AA is classified as basic even though its pK is 6.5 to 7?






21. What vitamin deficiency produces homocystinuria and methylmalonic aciduria?






22. What enzyme catalyzes the rate - limiting step in pyrimidine synthesis?






23. Is most of the coronary artery blood flow during systole or diastole?






24. What autoimmune disorder is due to Abs directed to ACh receptors at the NMJ?






25. Name the associated chromosomal translocation - Follicular lymphoma






26. What type of Plasmodium affects x RBCs of all ages?






27. What endocrine abnormality is characterized by the following changes in PTH - Ca2+ - and inorganic phosphate (Pi)? - PTH decreased - Ca2+ decreased - Pi increased






28. What syndrome is seen in iron - deficient middle - aged women with esophageal webs?






29. What happens to the following during skeletal muscle contraction? - Actin and myosin lengths






30. Name the end product or products: x Fatty acid oxidation






31. What subtype of IgG does not bind to staphylococcal A protein?






32. What wave is the cause of the following venous pulse deflections? - The bulging of the tricuspid valve into the right atrium






33. Regarding neuroleptics - What is the relationship between potency and anticholinergic side effects?






34. Where are the tonsillar tissues?

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35. Name the type of graft described by these transplants: x From one site to another on the same person






36. What blotting technique uses the following for analysis? - RNA






37. What congenital small bowel outpouching is a remnant of the vitelline duct?






38. Name the DNA virus x Linear dsDNA; nuclear envelope; icosahedral; replicates in the nucleus






39. What form of arthritis is associated with calcium pyrophosphate crystals?






40. Inhibits glucose uptake in skeletal muscle.






41. What are the three sites where CSF can leave the ventricles and enter the subarachnoid space? (Name the lateral and the medial foramina.)






42. What are the four most common causes of femoral head necrosis?






43. What is the major ketone body produced during alcoholic ketoacidosis?






44. What Ig is associated with mucosal surfaces and external secretions?






45. What leukemia affects a 4-year - old child with 3 months of fever - fatigue - generalized lymphadenopathy - CNS involvement - hepatosplenomegaly - bleeding - and platelet count below 100 - 000?






46. What bursa is inflamed in clergyman's knee?






47. What part of the heart forms x The right border?






48. What enzyme catalyzes the rate - limiting step of the urea cycle?






49. What agent used in the treatment of BPH and baldness is a 5- a - reductase inhibitor?






50. Is GH considered a gluconeogenic hormone?







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