Test your basic knowledge |

USMLE Step 1 Prep

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What is the term for the negative resting membrane potential becoming more negative?






2. Name the antidote - Isoniazid






3. What color do fungi stain with PAS? Silver stain?






4. What enzyme catalyzes the rate - limiting step of the urea cycle?






5. What is the name of the superficial subcutaneous fascia of the abdomen containing fat?

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6. How is velocity related to the total cross - sectional area of a blood vessel?






7. Which phenotype of osteogenesis imperfecta is incompatible with life?






8. What complex is needed for propionyl CoA carboxylase?






9. What viral infection is known to cause intracerebral calcifications?






10. Name the T- cell CD marker: x Interacts with MHC class II molecules






11. What reflex enables the eyes to remain focused on a target while the head is turning?






12. Causes of avascular necrosis of bone.






13. What is associated with prolonged lithium use?






14. What is the major Ab of the primary immune response?






15. When do hCG concentrations peak in pregnancy?






16. Are antineoplastic agents that work on actively proliferating cells schedule or dose dependent?






17. What area of the hypothalamus is responsible for recognizing a decrease in body temperature and mediates the response to conserve heat?

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18. Name the antidote - Heparin






19. What negative sense RNA virus is associated with intracytoplasmic inclusion bodies called Negri bodies?






20. What phase of the female cycle occurs during days 1 to 15?






21. What phosphodiesterase inhibitor is used IV in the management of status asthmaticus ?






22. What pathology is associated with deposition of calcium pyrophosphate in patients older than 50 years?






23. What is the FiO2 of room air?






24. What is the central issue regarding the Roe vs. Wade decision (legalization of abortion)?






25. What AR disorder is due to a deficiency in glycoprotein IIb - IIIa - resulting in a defect in platelet aggregation?






26. What enzyme catalyzes the rate - limiting step in gluconeogenesis?






27. What type of questions should you begin with when a patient seeks your medical opinion?






28. In What area of the GI tract does iron get absorbed?






29. What two AAs have a pKa of 10?






30. What CNS tumor arises from Rathke's pouch?






31. What rare disorder presents as a large - hard - irregular thyroid gland due to fibrous proliferation of connective tissue in the thyroid gland and extends to adjacent structures?






32. What is the precursor of all sphingolipids?






33. What glycogen storage disease is due to the following enzyme deficiencies? - Glucose -6- phosphatase

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34. What pathophysiologic disorder is characterized by the following changes in cortisol and ACTH? - Cortisol decreased - ACTH decreased






35. Where is the cupola of the lung in relation to the subclavian artery and vein?






36. What endocrine abnormality is characterized by the following changes in PTH - Ca2+ - and inorganic phosphate (Pi)? - PTH decreased - Ca2+ decreased - Pi increased






37. Name the most common type or cause - GN in the world






38. What is used as an index of cortisol secretion?






39. Name the RNA subtype based on the following: x RNA molecules with enzymatic activity






40. Signet ring cells






41. What is the difference between a Ghon focus and a Ghon complex?






42. What is the classic triad of TB?






43. What is the vector of African sleeping sickness?






44. What toxicities are caused by the following agents? - Halothane






45. What are the two ways that nitrogen can enter into the urea cycle?






46. Which acid - fast rod is an obligate intracellular parasite?






47. What happens to the following during skeletal muscle contraction? - I band






48. What urinary metabolite is elevated in pheochromocytoma?






49. What excitatory fibers arise from the inferior olivary nuclei on the contralateral side of the body?






50. What pathophysiologic disorder is characterized by the following changes in cortisol and ACTH? - Cortisol increased - ACTH increased