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USMLE Step 1 Prep

Subjects : health-sciences, usmle-step-1

Instructions:

Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can study here.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. What are the pharmacologic effects seen sexually with x a1- Blockers?
CN V1 - the occulomotor division of the trigeminal nerve - is the sensory component of the corneal reflex.
HTLV-1
Epinephrine
Impaired ejaculation

2. What is the term for panhypopituitarism secondary to ischemic necrosis and hypotension postpartum?
Sheehan syndrome
RNA polymerase II
Concrete operations (6-12 years)
Catechol - O- methyl transferase (COMT)

3. What paraphilia is defined as x Combining sex with defecation?
Coprophilia
Papillary carcinoma of the thyroid
Itraconazole
Craniopharyngioma

4. Anhedonia - lack of motivation - feelings of worthlessness - decreased sex drive - insomnia - and recurrent thoughts for at least 2 weeks - representing a change from previous level of function - describes what disorder?
In the PNS - myelin is produced by Schwann cells - in the CNS by oligodendrocytes.
Concentration force and electrical force
Unipolar disorder (major depression)
Central sulcus (sulcus of Rolando)

5. What is the name of bilateral flaccid paralysis - hyporeflexia - and hypotonia due to a viral infection of the ventral horn of the spinal cord?
Sarcoplasmic reticulum
Succinyl CoA synthetase
Median nerve
Poliomyelitis; it is a bilateral LMN lesion.

6. Which IL increases IgA synthesis?
Baseline apical intrapleural pressure is -10 cm H2O (more negative than the mean) resulting in a force to expand the alveoli.
IL-5. It also stimulates eosinophil proliferation.
The urine becomes hypertonic because of water reabsorption in the collecting duct.
Inhibited orgasm

7. What lymphoid organ is characterized by germinal centers - plasma cells that secrete IgA - and no encapsulation?

8. What are the three rules of clonal selection?
Teeth grinding is associated with stage 2 sleep.
1. One cell type 2. One Ab type 3. Random selection of hypervariable regions - and only cells with bound Ag undergo clonal expansion
Familial polyposis coli
CD8

9. Senile plaques
Alzheimer disease
Clostridium perfringens
The lateral vestibular nucleus
G1 phase (gap 1)

10. What are the adult remnants of the following structures? - Foramen ovale
The bifurcation of the abdominal aorta
Lysine and tyrosine
Fossa ovale
Oxygen

11. Are the following conditions associated with a negative or positive nitrogen balance? - Growth
GnRH pulsatile infusion
Positive
Kayser - Fleischer rings
Plasma cell (mature B lymphocyte)

12. What diseases are associated with the HLA- DR3 allele

13. What lower extremity nerve is described by the following motor loss? - Loss of adduction of the thigh
ACE inhibitors (- pril)
The energy of activation (Ea)
Hepatitis D
Obturator nerve

14. What area of the retina consists of only cones and has the greatest visual acuity?
Mesencephalon
C5- C9
Fovea
Cholera toxin irreversibly activates the cAMP- dependent chloride pumps of the small and large intestine - producing a large volume of chloride - rich diarrhea.

15. What is the name of the B cell - rich area of the spleen?
Primary follicle (in the white pulp)
Hypokalemic metabolic alkalosis occurs from vomiting because of the loss of H+ - K+ - and Cl -.
Metastatic carcinomas
Dilator pupillae muscle

16. What is the site of action of the following? - K+- sparing diuretics
Caisson disease
Early collecting duct
Vesicular stomatitis virus
Splenomegaly and anemia (with a high index of suspicion)

17. What factors are needed for elongation in prokaryotes?
Proencephalon diencephalon derivative
Kupffer cells
EF- Tu or EF- ts and GTP
Haemophilus ducreyi

18. What projective test asks the patient to tell a story about What is going on in the pictures - evaluating the conflicts - drives - and emotions of the individual?
TAT (Thematic apperception test)
G0 phase
1. Exercise 2. Emergencies (stress) 3. Exposure to cold (The three Es)
a -1 - 6 transferase

19. Where do adult tapeworms develop - in the intermediate or definitive host?
Prolactinoma
Adult tapeworms develop in the definitive host - whereas cysticerci or larvae develop in the intermediate host.
Prodrugs
Rhabdomyoma

20. What is the most common one? - Testicular tumor in men over 50 years old
Crohn disease
Antisocial personality
Filiform papillae
Testicular lymphoma

21. Calf pseudohypertrophy
Ultralente
Vimentin
Duchenne muscular dystrophy
Cystadenocarcinoma

22. What is the MCC of death in children aged 1 to 14 in the United States?
The enzyme lysyl oxidase requires Cu2+and O2 to function properly.
The parafollicular cells of the thyroid (C cells) release calcitonin in response to hypercalcemia.
Accidents
NADPH oxidase

23. What is the most common causative organism of acne vulgaris?
Excess lead
Metronidazole
Propionibacterium acnes
Leucine and lysine

24. What Ab is an indication of recurrent disease for hepatitis?
HBc Ab
competency
Plasma cell
Nitroprusside

25. What potentially fatal disease occurs in children who are given aspirin during a viral illness?
Hurler syndrome and Hunter syndrome - respectively
Mesonephric duct
Neurofibromatosis
Reye syndrome

26. What is the term for having fantasies or dressing in female clothes for sexual arousal by heterosexual men?
Transvestite fetishism
Cell - mediated immunity
Hemostasis
Klinefelter syndrome

27. What AR CNS disorder presents early in childhood with gait ataxia - loss of deep tendon reflexes - impaired vibratory sensation - hand clumsiness - and loss of position sense?
Chromosome 11 - 22
Trazodone
Friedreich ataxia
1. Nails 2. Hair 3. Sweat glands (both apocrine and sebaceous)

28. What complement factor or factors are associated with x Membrane attack complex (MAC)?
The pulsatile release of GnRH
Avoidant
C5- C9
Cocaine

29. What is the term for pelvic inflammatory disease of the fallopian tubes?
Where the cell bodies for the DCML and spinothalamic sensory systems are...
Stable angina
Salpingitis
Need 3 panic attacks over 3 weeks (remember - they come out of the blue.)

30. Shuffling gait - cogwheel rigidity - masklike facies - pill - rolling tremor - and bradykinesia describe what form of dementia?

31. What case is known as 'let nature take its course'?
Infant Doe. Generally - parents cannot forego lifesaving treatment - but this case states that there are exceptions to the rule.
Oxytocin
RBCs. That is why it is called red pulp.
Mantle cell lymphoma

32. Name the antidote - Cyanide
Amyl nitrate - sodium nitrate - or sodium thiosulfate
Acid is needed for the activation of pepsin and therefore needed for protein digestion.
Chromosome 21
1. Laminin 2. Heparan sulfate (heparitin sulfate) 3. Fibronectin 4. Type IV collagen

33. What is the most serious form of tinea capitis - which results in permanent hair loss and is highly contagious?
Pertussis toxin
Osteosarcoma
Tinea favosa (favus)
Ependymal cells

34. Name the MCC - Aspiration pneumonia in an alcoholic
Klebsiella pneumoniae
It repeats every 90 to 120 minutes and correlates with elevated levels of motilin.
Staphylococcus aureus
Inspiratory capacity

35. What are the three causes of transudate?
Hyaluronic acid (all sulfates bind to the core protein)
CHF - cirrhosis - and nephrosis
Ciliary ganglion
Resistance increases as resistors are added to the circuit.

36. What form of bilirubin is carried on albumin?
Muscle spindles
The carotid sinus reflex
Papule
Unconjugated (indirect)

37. What hormones are produced in the median eminence region of the hypothalamus and the posterior pituitary gland?
None; they are the storage sites for ADH and oxytocin.
Xanthine oxidase
Al - Anon
X- linked recessive

38. What would be the result if an Ab were cleaved with papain?
Bacillus cereus
Diverticulosis
Stable (Labile cells proliferate throughout life; stable cells have a low level of proliferation; and permanent cells as the name states - do not proliferate.)
There would be two Fab and Fc regions.

39. What is the term for normal cellular genes associated with growth and differentiation?
Proto - oncogenes
Microglia (Microglia and mesoderm both begin with M)
Squamous cell carcinoma (skin - lung) and angiosarcoma of the liver
Osteogenesis imperfecta

40. What result occurs because of the negative alveolar pressure generated during inspiration?
Air flows into the respiratory system.
CMV; Toxoplasma also causes intracerebral calcifications but it is a parasite.
Niemann - Pick disease
Superior and posterior

41. What lysosomal enzyme is deficient in x Tay- Sachs disease?
Vesicular stomatitis virus
P24
Hexosaminidase A
4 years old

42. What type of Plasmodium affects x Only reticulocytes?
1. Glucagon 2. NADH 3. Acetyl CoA 4. ATP
Plasmodium vivax
Plasmodium falciparum
Viscosity and resistance are proportionally related. The greater the viscosity - the greater the resistance is on the vessel.

43. What Ig is the major protective factor in colostrum?
Chromosome 8 - 14
1. Phosphorylation of mannose (lysosomes only) 2. Removal of mannose residues 3. Formation of glycosylate proteins 4. Phosphorylation of sulfate amino acids
IgA
Dysgerminoma

44. What deep cerebellar nuclei receive Purkinje cell projections in x The intermediate hemispheres?
Selegiline
5HT1D
The dentate nucleus
Gestational trophoblastic neoplasia (GTN or choriocarcinoma)

45. Name the thalamic nucleus based on its input and output - Input from the trigeminal pathways; output to primary somatosensory cortex of the parietal lobe
Ventral posteromedial nucleus
Testosterone
IgG
NH4+(ammonium)

46. What CN is associated with the sensory innervation of x Laryngopharynx?
Nicotinic acid - because its side effects include hyperuricemia and exacerbation of ulcers.
Cilia
Variola virus (Smallpox)
Vagus nerve

47. What genus is known as the smallest free living bacteria? (hint: has no cell wall and has sterols in the membrane)
Mycoplasma
It repeats every 90 to 120 minutes and correlates with elevated levels of motilin.
Prevalence increases. (Remember - prevalence can decrease in only two ways - recovery and death.)
The pathologic problem with CO poisoning is that CO has 240 times as much affinity for Hgb molecule as does O2 - reducing the carrying capacity and shifting the curve to the left - making it difficult to remove the CO molecule from Hgb.

48. What is the term for the number of new events occurring in a population divided by the population at risk?
Antisocial
Palatoglossus muscle is innervated by CN X; all other tongue muscles are innervated by CN XII.
Incidence rate
Campylobacter jejuni

49. What is the only diuretic that works on the blood side of the nephron?
1. The child poses an imminent danger to self or others. 2. The child is unable to self - care daily at the appropriate developmental level. 3. The parents or guardians have no control over the child or will not promise to ensure the child's safety e
Al - Anon
S phase
Spironolactone (binds to aldosterone receptors)

50. Name the form of spina bifida - Meninges and spinal cord project through a vertebral defect
P wave
Meningomyelocele All except occulta cause elevated - fetoprotein levels.
PRPP aminotransferase
Chlamydia psittaci