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USMLE Step 1 Prep

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What disorder is associated with spider angiomas - palmar erythema - gynecomastia - testicular atrophy - encephalopathy - abnormalities in clotting factors - and portal HTN?






2. What syndrome is associated with the following brainstem lesions? - Vertebral artery or anterior spinal artery occlusion - resulting in contralateral corticospinal tract and medial lemniscus tract deficits and an ipsilateral CN XII lesion






3. What causes the lysis of RBCs by oxidizing agents in a G-6- PD deficiency?






4. What organism is commonly associated with a cellulitis from an animal bite?






5. What happens to diastolic and systolic intervals with an increase in sympathetic activity?






6. Which hepatitis B serology markers






7. What is the MCC of inherited mental retardation?






8. What is the MCC of the following meningitides? - In those 12 months to 6 years of age






9. Do you monitor heparin's therapeutic levels by PT or PTT?






10. Kayser - Fleischer rings






11. What is the most common chromosomal abnormality associated with CLL?






12. What artery is formed by the union of the two vertebral arteries?






13. What chromosome codes for HLA gene products?






14. Why is the cell's resting membrane potential negative?






15. Which region of the variable domain comprises the Ag - binding site of the Ab?






16. What cytokine do Th1 cells secrete to inhibit Th2 cell function?






17. What are the two factors that affect alveolar PCO2 levels?






18. What type of pleura is adherent to the surface of the organ?






19. What is the term for black pigmentation of the colon associated with laxative abuse?






20. What form of nephritic syndrome is associated with celiac sprue and Henoch - Sch






21. Are the following major or minor Jones criteria of rheumatic fever? - Sydenham chorea






22. What are the five branches of the superior mesenteric artery?






23. Which leukotriene is chemotactic for neutrophils?






24. What cells are atypical on a peripheral blood smear in heterophil - positive mononucleosis?






25. What term describes how an action potential is propagated along an axon?






26. A schizophrenic patient who is taking haloperidol is brought to your ER with muscle rigidity - a temperature of 104






27. What is the term for the pH at which the structure carries no charge?






28. If a drug is ionized - is it water or lipid soluble? Can it cross a biomembrane?






29. What is the most common one? - Helminth parasitic infection in the United States






30. What MHC class acts to remove foreign Ags from the body?






31. What tumor is derived from primitive streak remnants and often contains bone - hair - or other tissue types?






32. What protein carries free fatty acids to the liver?






33. Name the B- cell CD marker: x Required for class switching signals from T cells






34. What mast cell mediator is a chemotactic agent?






35. What pneumoconiosis is associated with exposure to the following occupations or materials? - Miners - metal grinders - and sandblasters

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36. Name the antidote - Benzodiazepines






37. What are the three main components of amyloid?






38. Name the DNA virus: x Linear dsDNA; naked; replicates in the nucleus






39. What is the best measure of total body vitamin D if you suspect a deficiency?






40. Name the cancer associated with the following oncogenes. (Some may have more than one answer) x hst -1 and int -2






41. Via what cell surface receptor does HDL cholesterol from the periphery enter hepatoceles?






42. What is the only vein in the body with a high O2 content?






43. Name the type of regeneration (i.e. - labile - stable - or permanent) based on the following examples - Hematopoietic cells






44. What pathophysiologic disorder is characterized by the following changes in cortisol and ACTH? - Cortisol increased - ACTH decreased






45. What type of metal poisoning causes mental retardation - somnolence - convulsions - and encephalopathy?






46. In what cycle does glucose go to the muscle - where it is converted to pyruvate and then into alanine before being taken back to the liver?






47. What antifungal agent is activated by fungal cytosine deaminase to form 5- FU?






48. Both submandibular and sublingual glands are innervated by CN VII (facial) and produce mucous and serous secretions. Which one mainly produces serous secretions?






49. On the venous pressure curve - What do the following waves represent? - A wave?






50. Influenza - Vibrio cholera - hepatitis A - rabies - and adenovirus.