Test your basic knowledge |

USMLE Step 1 Prep

Subjects : health-sciences, usmle-step-1

Instructions:

Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can study here.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. What Ig prevents bacterial adherence to mucosal surfaces?
Functions of hepatocytes
Leukotriene B4 (LTB4)
Posterior hypothalamic zones; lesions here result in poikilothermy (environmental control of one's body temperature).
IgA

2. What artery travels with the following veins? - Great cardiac vein
Left anterior descending artery
Streptococcus viridans
Mycosis fungoides (cutaneous T- cell lymphoma)
Dopamine levels rise with waking; dopamine is associated with wakefulness.

3. Ophthalmic artery is a branch of What artery?
IL-2. T cells express IL-2 receptors on their surface to induce self - expression.
Leiomyoma
Internal carotid artery
T cells - not B cells

4. What is the longest and most convoluted segment of the nephron?
PCT
Atropine with pralidoxime
Nearly 50% of all reported cases of elderly abuse are due to neglect. Physical - psychological - and financial are other forms of elderly abuse with an overall prevalence rate of 5% to 10%.
Avidity (more than one binding site)

5. Describe the organism based on the following information: x Beta - hemolytic Streptococcus sensitive to bacitracin
Decreases Remember - the carotid sinus reflex attempts to compensate by increasing both TPR and heart rate. -------------------------------------------------------------------------------
5' deiodinase
Leydig cell tumor
Streptococcus pyogenes

6. What is the name of the postganglionic parasympathetic ganglion that innervates x The submandibular and sublingual glands?
The submandibular ganglion. (Submandibular ganglion innervates the submandibular gland; easy enough.)
When the pH is more acidic than the pI - it has a net positive charge - and when the pH is more basic than the pI - it has a net negative charge.
Clostridium tetani
Autoimmune hemolytic anemia

7. Which streptococcal species is characterized by being catalase negative - turning bile esculin agar black - producing a positive PYR test - and resulting in biliary and urinary tract infections?
Posterior chamber
FSH
Enterococcus (Streptococcus faecalis)
A loss of afferent activity indicates a decrease in BP - and an increase in afferent activity indicates an increase in BP.

8. What nerve supplies general sensation to the anterior two - thirds of the tongue?
Fitz - Hugh - Curtis syndrome
Lingual nerve of CN V3
Testicular tumors
Normal thyroid hormones levels in the plasma are necessary for proper secretion of GH. Hypothyroid patients have decreased GH secretions.

9. Name the antimicrobial agent whose major side effect is listed - Teratogenicity
Epidermophyton
Flumazenil
Metronidazole
Clostridium botulinum

10. Where does Beta - oxidation of very long chain fatty acids begin?
Flea - bitten kidney (can also be seen in pyelonephritis)
In the peroxisome until it is 10 carbons long; the rest is completed in the mitochondria.
Pneumocystis carinii
Phallus

11. What segments of the lumbosacral plexus form the following nerves? - Obturator nerve
L2 to L4 (L2 to L4 - thigh; L4 to S3 - leg)
Clearance
Rhombencephalon
C5a

12. What mosquito is the vector for dengue fever?
Molindone
Gastric cancer
Gynecomastia
Aedes (the same for yellow fever)

13. What is the most common one? - Skin tumor in the United States
Carbamazepine
Eosinophilic exudates
Basal cell carcinoma
Hemiballismus

14. In the alveoli - what cell type is x part of the mononuclear phagocytic system?
Alveolar macrophages (dust cells)
LGB (think EYES)
Previous suicide attempt
Guillain - Barr

15. How does ventricular repolarization take place - base to apex or vice versa?
Repolarization is from base to apex and from epicardium to endocardium.
Secondary lysosome (think of the primary as inactive and secondary as active)
NADPH - O2 - and cytochrome b5
Allopurinol

16. What is the only DNA virus that has the reverse transcriptase enzyme?
Medial pontine syndrome
Temporal lobes
Early distal tubule
Hepadnavirus

17. What is the most common fungal infection in HIV?
Simon focus
Candida
Para - aminohippurate (PAH)
Sjogren's syndrome - active hepatitis - systemic lupus erythematosus (with HLA- DR2) and type 1 diabetes (with HLA- DR4)

18. There are no persistent infections with...
naked viruses
Southern blot
Breast cancer
Double - blind study. It is the most scientifically rigorous study known.

19. What components of the complement cascade form the MAC?
ASA (salicylate)
C5b - C9
Haemophilus influenzae type B
The wall tension is greater because the aneurysm has a greater radius than the surrounding vessel.

20. What is a sign of a Sertoli cell tumor in a man?
Liquefaction necrosis
Excess estradiol in the blood
Corticosteroid
Rhabdomyoma

21. What hormone is characterized by the following renal effects? - Calcium excretion - phosphate excretion
Fungiform papillae
Lead
Calcitriol
Beta2- integrins

22. All aluminum - containing antacids can cause...
Two major or one major and two minor
hypophosphatemia
Doxycycline and minocycline
Complex 4

23. What thyroid abnormality has the following? - TRH increased - TSH decreased - T4 decreased
CSF
Marfan syndrome
Secondary hypothyroidism/pituitary (Low TSH results in low T4 and increased TRH because of lack of a negative feedback loop.)
Secretin stimulates the pancreas to secrete a HCO3-- rich solution to neutralize the acidity of the chyme entering the duodenum.

24. What substance is secreted by parietal glands and is required for life?
90% of benign myxomas arise within the left atrium near the fossa ovalis.
Intrinsic factor (IF)
Ovarian cancer
Prolyl and lysyl hydroxylases

25. What bonds are broken by exonucleases?

Warning: Invalid argument supplied for foreach() in /var/www/html/basicversity.com/show_quiz.php on line 183

26. Name the macrophage based on its location: x Brain macrophages
They chronically inhibit ADH secretion; when there is a decrease in the blood volume - the stretch receptors send fewer signals - and ADH is secreted.
Chlamydia
Microglia
The systemic veins have the largest blood volume - and the pulmonary veins have the second largest blood volume in the cardiovascular system. They represent the reservoirs of circulation.

27. Name the valve abnormality based on the following criteria: x Diastolic murmur; increased preload - stroke volume - and aortic pulse pressure; decreased coronary blood flow; no incisura; and peripheral vasodilation
Lateral cricoarytenoid muscles
CO
Bunyavirus
Aortic insufficiency

28. Name the Plasmodium species based on the following information: No persistent liver stage or relapse; blood smear shows multiple ring forms and crescent - shaped gametes; irregular febrile pattern; associated with cerebral malaria
Plasmodium falciparum
de Quervain thyroiditis
Chromosome 11p
Formation of an identity through issues of independence and rebellion; they define who they are.

29. What complement factor or factors are associated with x Opsonization?
Deficiency in surfactant
Phase 1
C3b
Carbidopa and benserazide

30. What artery supplies most of the lateral surfaces of the cerebral hemispheres?
Osteoarthritis
Infection
Stable angina
Middle cerebral artery

31. What three Beta- blockers are used in the treatment of glaucoma?
Stable
NADPH oxidase is deficient - resulting in an inability to produce toxic metabolites.
Site 3
1. Propranolol 2. Timolol 3. Carteolol

32. In what stage of sleep is GH secreted?
Stages 3 and 4 (NREM)
<2
Human chorionic somatomammotropin (hCS) or human placental lactogen (hPL)
Stable

33. What is the only muscle of the soft palate that is innervated by CN V3?
The tensor veli palatine is innervated by the mandibular division of the trigeminal nerve; all others are innervated by CN X.
Thermogenic
Superior
total body water

34. In a parallel circuit - what happens to resistance when a resistor is added in parallel
Right - sided valves
Inactivated
Breast and lung cancer - respectively.
Resistance decreases as resistors are added in parallel.

35. What drug is being given to HIV- positive mothers during labor and to the children after birth to decrease the risk of mother - to - child HIV transmission?
Positive sense RNA can be used as mRNA. Negative sense RNA cannot be used as mRNA; it requires special RNA- dependent RNA polymerases.
Chondroitin sulfate and keratan sulfate
Nevirapine; it cuts the rate from 20% to 10%. AZT is also used - cutting the rate from 20% to 10%.
Dystrophic calcification

36. Which type of hepatitis is a calicivirus?
Ependymoma
Tip of the loop of Henle (1200 mOsm/L)
Hepatitis E (enteric)
Renal cell carcinoma

37. What class of drugs is used in the treatment of demineralization of the bone?
Bisphosphonates
Oxygen
Primary hypercortisolism
50%. The uncles and older siblings are the most likely perpetrators - although stepfathers also have a high rate.

38. What type of GN occurs most commonly in children after a pharyngeal or skin infection; is immune complex- mediated; and is seen as lumpy- bumpy subepithelial deposits?
Postinfectious GN
EF-2 and GTP
Actually - yes. You should encourage your patient to try other forms of medicine as long as they are not contraindicated with the patient's preexisting illness. You must be able to accept the health beliefs of your patients - even if you don't agree.
Mitochondria - linked disorders are always inherited from the mother.

39. Readily diffuses across the blood - brain barrier.
Type IV hypersensitivity reaction (delayed type because of the 48-96 hour latency)
Aspartate transcarbamylase
Glucose
Berry aneurysm in the circle of Willis

40. What is the label given to an individual whose IQ is x Below 69
Aspartate transcarbamylase
Mentally disabled
Azathioprine
X- linked recessive

41. What form of hemophilia is X- linked recessive and due to a deficiency in factor VIII?
Ungated channels
Medial umbilical ligaments
Hemophilia A
Subthreshold potential

42. What syndrome results when there is a deletion to paternal chromosome 15? Maternal?
Ostium secundum defects
Phase 1
Depression
Prader - Willi syndrome and Angelman syndrome - respectively

43. Blood and its vessels form During What embryonic week?
Third week; they are derived from the wall of the yolk sac.
Spironolactone
Granulosa cell
Complex 4

44. Deposits in the oral cavity.
Excess lead
Group A Beta- hemolytic streptococci
Transverse abdominis
Minor

45. What is the MCC of the following meningitides? - In those 12 months to 6 years of age
The entire tubule barring the thick ascending limb
Carnitine acyltransferase I
Haemophilus influenzae type B
S phase

46. What tetracycline is associated with hepatotoxicity?
IL-2. T cells express IL-2 receptors on their surface to induce self - expression.
Chlortetracycline
The fastigial nucleus
Fibrocystic change of the breast

47. Name the most common type or cause - Urinary tract obstruction
BPH
NE
Action potential
Substantia nigra

48. Name the antidote - Copper
Membranous glomerulonephritis
Cortisol
Histiocytosis X
D- Penicillamine

49. What parasitic infection is associated with cholangiocarcinoma?
Clonorchis sinensis
CN II is the sensory limb and CN III is the motor component through parasympathetic stimulation.
After the latent period
All

50. During what stage of B- cell development is IgM first seen on the surface?
1. IgA receptor 2. Transport of IgA across epithelial barriers 3. Protection of IgA from degradative proteases
Wilms tumor
Autoimmune thrombocytopenia purpura
Immature B cells