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USMLE Step 1 Prep

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What tumor is derived from primitive streak remnants and often contains bone - hair - or other tissue types?






2. What is the most common one? - Cancer of the vulva






3. What cell type of the epidermis functions as antigen - presenting cells?






4. What bone disorder is characterized by brown tumors - bone pain - deformities - and fractures due to excessive PTH?






5. What immunologic test checks for a reaction between Abs and a particular Ag? (hint: ABO typing)






6. What are the two reasons for megaloblastic anemia with elevated MCV?






7. What three cephalosporins have good penetration against Bacteroides fragilis?






8. What is the MCC of viral conjunctivitis?






9. Name the DNA virus x Linear dsDNA; nuclear envelope; icosahedral; replicates in the nucleus






10. What type of cell is surrounded by mineralized bone?






11. Name the ventricular muscle membrane channel: x Open at rest; depolarization is stimulus to close; begin to reopen during the plateau phase and during repolarization






12. What is the teratogenic effect associated with lithium?






13. What fat - soluble vitamin is connected to selenium metabolism?






14. What is the rate - limiting step of the following? - Ketogenolysis






15. From What embryonic structure are the following structures derived? - The right and left ventricles






16. Is DM a contraindication to use of a Beta- blocker in a patient who is having an MI?






17. What two factors result in the base of the lung being hyperperfused?






18. What is the respiratory compensation mechanism for metabolic alkalosis?






19. What disease is described by the following characteristics: multiple motor and vocal tics - average age of onset 7 - a M:F ratio of 3:1 - and association with increased levels of dopamine?

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20. What branch off the vertebral artery supplies x The ventrolateral two - thirds of the cervical spinal cord and the ventrolateral part of the medulla?






21. What test uses very small amounts of DNA that can be amplified and analyzed without the use of Southern blotting or cloning?






22. What is the direction of growth for the primitive streak - caudal to rostral or rostral to caudal?






23. How many milliliters of O2 per milliliter of blood?






24. What is the effect of hypoventilation on cerebral blood flow?






25. What phobia is described as the fear of open spaces?






26. What prion - associated CNS pathology produces rapidly progressive dementia with myoclonus - involuntary movements - and death within 6 to 12 months?






27. What triggers phase 3 of the action potential in a ventricular pacemaker cell?






28. What intermediate enables propionyl CoA to enter into the TCA cycle?






29. What is the only way to increase the Vmax of a reaction?






30. What lower extremity nerve is described by the following motor loss? - Loss of adduction of the thigh






31. Name these narcissistic defense mechanisms: x Person takes his or her own feelings - beliefs - wishes - and so on and thinks they are someone else's. (e.g. - a cheating man thinks his wife is unfaithful)






32. Where does the conversion of CO2 into HCO3- take place?






33. Although the CSF normally contains 0 to 4 lymphocytes or monocytes - the ___________ is always considered abnormal.






34. What components of the coagulation cascade are affected by estrogen?






35. What are the three microscopic pathologic changes seen in Alzheimer's disease?






36. What is the term for hypoperfusion of an area involving only the inner layers?






37. What cells of the epidermis carry the pigment melanin?






38. What is the DOC for esophageal candidiasis?






39. Name the ocular lesion; be specific - Right calcarine cortex lesion






40. What childhood pathology involves anterior bowing of the tibia - epiphyseal enlargements - and costochondral widening - with the endochondral bones being affected?






41. Name the associated chromosome - Albinism






42. What ovarian disease involves psammoma bodies?






43. Innervate the striated muscle of the bulbospongiosus and ischiocavernous muscles and result in ejaculation of semen.






44. Name the nephritic disease based on the immunofluorescent staining - Smooth and linear pattern of IgG and C3 in the GBM






45. What is the most common one? - Malignancy in children






46. What pathology is associated with deposition of calcium pyrophosphate in patients older than 50 years?






47. What is the rule of one - third regarding muscle type of the esophagus?






48. What AD renal disorder is associated with mutations of the PKD 1 gene on chromosome 16 and berry aneurysms in the circle of Willis and presents in the fifth decade with abdominal masses - flank pain - hematuria - HTN - and renal insufficiency?






49. Lewy bodies






50. Neurofibrillary tangles







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