Test your basic knowledge |

USMLE Step 1 Prep

Subjects : health-sciences, usmle-step-1

Instructions:

Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can study here.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. What thyroid carcinoma is associated with radiation exposure - psammoma bodies - and Orphan Annie eye nuclei?
Renin secretion
Papillary carcinoma of the thyroid
The ECF compartment always enlarges when there is a net gain in total body water and decreases when there is a loss of total body water. Hydration status is named in terms of the ECF compartment.
gram positive

2. What type of correlation is defined as x One variable that diminishes in the presence of the other?
HBcAb and HBeAb. You see the antibodies c and e.
Negative correlation
Somatization
Aortic insufficiency

3. What is the major Ab of the primary immune response?
Nitrofurantoin
Propionic acid
IgM
Sadism

4. Regarding neuroleptics - What is the relationship between potency and anticholinergic side effects?
Inversely proportional: the higher the potency - the lower the anticholinergic side effects.
REM
Undoing
Ulcerative colitis

5. What hormone's release is strongly associated with stage 4 sleep?
Secondary hypercortisolism (pituitary)
Lente insulin and either NPH or protamine zinc insulin (PZI)
GH. The largest output of GH in a 24- hour period is during stage 4 sleep.
Lymphoblastic lymphoma

6. What are the five hormones produced by Sertoli cells?
T4 - as long as T4 levels remain constant - TSH will be minimally effected by T3.
1. Inhibin 2. Estradiol (E2) 3. Androgen - binding protein 4. Meiosis inhibiting factor (in fetal tissue) 5. Antim
Free - unprocessed Ag
Patients with cystic fibrosis have a mutation in the chloride channel protein in the CFTR gene on chromosome 7.

7.
Risperidone
prior to birthThe foramen ovale closes just...
Histidine - because of the imidazole ring found in the R group - is basic.
Kayser - Fleischer rings

8. The first sensory neuron is in the dorsal root ganglia. It carries ascending sensory information in the dorsal root of a spinal nerve - eventually synapsing with second sensory neuron. In the brainstem (DCML) and the spinal cord (spinothalamic) the s
The venae recta maintain the gradient via countercurrent flow.
HBsAb IgG
Where the cell bodies for the DCML and spinothalamic sensory systems are...
ACh

9. What virus is associated with the endemic form of Burkitt lymphoma?
a -1 - 6 transferase
GH- producing adenoma
Parvovirus B-19
EBV

10. What are the three C's of measles?
1. Cough 2. Coryza 3. Conjunctivitis
Breast cancer
5- hydroxyindoleacetic acid (5- HIAA)
Glucose -6- phosphatase

11. After fertilization - what cells of the corpus luteum x Secrete progesterone?
Primary follicle of the cortex
Chlamydia psittaci
Granulose cells secrete progesterone. After fertilization the granulose cells form from follicular cells.
Malassezia furfur (treat with selenium sulfide)

12. What is released from the mitochondria to trigger apoptosis?
Picornaviridae
Berry aneurysm in the circle of Willis
Lentigo maligna melanoma
Cytochrome c

13. What enzyme found in a cholinergic synapse breaks down ACh? What are the byproducts?
CN V
Niacin (B3)
Acetylcholinesterase breaks ACh into acetate and choline (which gets resorbed by the presynaptic nerve terminal).
Nominal scale (categorical - e.g. - male or female)

14. Which a - blocking agent is used to treat refractory hypertension and baldness?
Minoxidil (orally and topically - respectively!)
The ECF compartment always enlarges when there is a net gain in total body water and decreases when there is a loss of total body water. Hydration status is named in terms of the ECF compartment.
Increase the concentration of enzymes
The placenta

15. What complement factor deficiency leads to x Recurrent gonococcal infections?
C5- C8 deficiency
Magnesium ammonium phosphate (struvite)
They prevent mast cell degranulation.
Addition (They are mutually exclusive.)

16. What is the term to describe the inability to feel any pleasant emotions?
The poly(A) site on the DNA
Silent
Anhedonia
MEN IIa (or Sipple syndrome)

17. What is the amount in liters and percent body weight for the following compartments? - Vascular fluid
Copper
Site 1
4.7 L - 5% of body weight
Borderline

18. How does ventricular repolarization take place - base to apex or vice versa?
Repolarization is from base to apex and from epicardium to endocardium.
Enterococcus faecalis
Postinfectious GN
Sj

19. What enzyme converts androgens to estrogens?
Substituted judgment. It is made by the person who best knows the patient - not the closest relative.
1. One cell type 2. One Ab type 3. Random selection of hypervariable regions - and only cells with bound Ag undergo clonal expansion
Aromatase
Mitral (bicuspid) valve

20. What congenital small bowel outpouching is a remnant of the vitelline duct?
Bordetella pertussis
Meckel diverticulum
Ulnar to radial progression
Labile

21. What type of mortality rate is defined as the number of deaths x From a specific cause per population?
Cause - specific mortality rate
At birth (reflex)
HBcAb IgM - HBV- DNA - HBeAg - HBsAg
Stimulus control

22. What is the most common one? - Female genital tract malignancy resulting in death
Ovarian cancer
Hemolytic uremic syndrome
hCS and serum estriol - which are produced by the fetal liver and placenta - respectively - are used as estimates of fetal well - being.
Chromosome 22q

23. What is the most common lethal AR disorder affecting white Americans?
Cystic fibrosis
Cohort studies determine incidence and causality - not prevalence.
Resistance of the system increases. (Remember - when resistors are connected in a series - the total of the resistance is the sum of the individual resistances.)
Fluconazole

24. Name the MCC of death - In diabetic individuals
MI
Mannitol
Posterior hypothalamic zones; lesions here result in poikilothermy (environmental control of one's body temperature).
Common peroneal nerve

25. Name these narcissistic defense mechanisms: x Not allowing reality to penetrate because afraid of becoming aware of painful aspect of reality.
Negative
Denial
Adrenarche
Heart rate determines the diastolic interval - and contractility determines the systolic interval.

26. Which leukotrienes are associated with the late - phase inflammatory response?
LTC4 and LTD4
Ag - Ab binding
The aorta has the greatest velocity and the capillaries have the slowest velocity.
Early distal tubule

27. What stage of male development is characterized by the following LH and testosterone levels? - Decreased testosterone production is accompanied by an increase in LH production.
Aged adult
Pons
Rickets
Pyruvate carboxylase

28. Craniopharyngiomas are remnants of what?

Warning: Invalid argument supplied for foreach() in /var/www/html/basicversity.com/show_quiz.php on line 183

29. What disease is seen in children younger than 5 years of age and is characterized by X- linked recessive cardiac myopathies - calf pseudohypertrophy - lordosis - protuberant belly - an increase then a decrease in CPK - and death commonly in the secon
Increase enzyme concentrations
Psoriasis
CSF H+ levels - with acidosis being the main central drive - resulting in hyperventilation (the opposite being true with alkalosis)
Duchenne muscular dystrophy

30. When is the first arrested stage of development in the female reproductive cycle?
In the first 3 months
Prophase of meiosis I (between 12th and 22nd week in utero)
Wernicke's encephalopathy
CHF - cirrhosis - and nephrosis

31. What medication is a PGE1 analog that results in increased secretions of mucus and HCO3- in the GI tract?
It is produced by the preload on the muscle prior to contraction.
Afterload
Misoprostol
Osteoma

32. What is the term for tissue - based basophils?
HBeAb
Mast cells
Increased leukocyte alkaline phosphatase (LAP)
Gastric cancer

33. What oxygen - dependent killing enzyme requires hydrogen peroxide and halide (Cl -) to produce hypochlorous acid?
P = .05; P < .05 rejects the null hypothesis
Glycerol kinase
Myeloperoxidase
Histidine

34. What is the primer for the synthesis of the second strand in production of cDNA from mRNA?

Warning: Invalid argument supplied for foreach() in /var/www/html/basicversity.com/show_quiz.php on line 183

35. What gene inhibits apoptosis by preventing the release of cytochrome c from mitochondria?
Recall bias. These problems arise in retrospective studies.
Bcl -2
Cocaine
TSH. 5- HT and prolactin increase during sleep - and dopamine levels decrease during sleep.

36. What muscle or muscles are innervated by the following nerves? - Upper subscapularis nerve
Constipation and miosis
Helicobacter pylori
Receptive aphasia is due to a lesion in Brodmann areas 22 - 39 - and 40; generally the patient is unaware of the deficit.
Subscapularis

37. What cell of the duodenum secretes CCK?
Enteroendocrine (EE) cells; they also secrete secretin.
Residual volume
Posterior chamber
Single - strand DNA binding protein

38. What is the term for different classes and subclasses of the same gene products?
Beta- Blockers
Roth spots - and they are seen in bacterial endocarditis.
Metronidazole
Isotypes

39. What is the tetrad of tetralogy of Fallot?
SHIP: Shifting of the aorta - Hypertrophy of the right ventricle - Interventricular septal defect - Pulmonary stenosis
Rheumatoid arthritis and type 1 diabetes (with HLA- DR3)
Secondary hyperparathyroidism (vitamin D deficiency - renal disease)
Muscle spindles

40. What pathology involves excessive fibrosis throughout the body via increased fibroblast activity - occurs in women more than men - and is most commonly seen in the third to the fifth decade?
Superego
Phase 2
Plasma cell
Scleroderma

41. What embryonic structure forms the adult female structures? - Ovary - follicles - rete ovarii
Infrapatellar bursa
Melanosis coli
Gonads
C5- C9

42. What is the major hormone produced in the following areas of the adrenal cortex? - Zona fasciculata
Cortisol Remember - from the outer cortex to the inner layer - Salt - Sugar - Sex. The adrenal cortex gets sweeter as you go deeper.
B- cell Ag receptors
Alendronate
Macrophages

43. Anhedonia - lack of motivation - feelings of worthlessness - decreased sex drive - insomnia - and recurrent thoughts for at least 2 weeks - representing a change from previous level of function - describes what disorder?
Ventral posterolateral nucleus
Constipation and miosis
Unipolar disorder (major depression)
Terminal bronchioles. (No gas exchange occurs here.)

44. How many ATPs are generated per acetyl coenzyme A (CoA)?
12 ATPs per acetyl CoA that enter the tricarboxylic acid (TCA) cycle (Krebs cycle)
Leukemias
Third week
Simple diffusion; it does not use protein - mediated transport

45. Based on operant conditioning - What type of reinforcement is described when x Removing a stimulus stops a behavior?
Phenytoin (cyclosporine and nifedipine also result in gingival hyperplasia)
CN I - II - III - VI - and XII Add 1 + 1 = 2 - 1 + 2 = 3 - 1 + 2 + 3 = 6 - 1 + 2 + 3 + 6 = 12
Increased androgen secretion at puberty drives the increased GH secretion.
Extinction

46. What complement factor deficiency leads to x Hereditary angioedema?
VSD - RVH - overriding aorta - and pulmonary stenosis
Zero - order elimination
C1 inhibitor (C1- INH)
Meckel diverticulum

47. What is the only CN nucleus found in the cervical spinal cord?
Cyclothymia (nonpsychotic bipolar). Patients are ego syntonic.
Pneumococcus (Streptococcus pneumoniae)
Loose association
Accessory nucleus

48. What subtype of schizophrenia is characterized by x Delusions of persecution and/or grandeur - auditory hallucinations - late onset - and the best prognosis?
Sulfonamides
Azathioprine
Paranoid schizophrenia
Vibrio vulnificus

49. What bactericidal agents are resistant to Beta- lactamases and are used to treat in - hospital life - threatening infections?
Malignancy
Denial
Metronidazole
Imipenem and meropenem

50. What nerve is associated with the following functions? - Innervation of the flexor carpi ulnaris - flexor digiti profundus (pinky and ring fingers) - and the intrinsic muscles of the hand
Tay- Sachs disease
As the standard deviation increases - the greater the chance of error.
Volvulus
Ulnar nerve

Can you answer 50 questions in 15 minutes?

Major Subjects
Tests & Exams AP CLEP DSST GRE SAT GMAT	Certifications CISSP go to https://www.isc2.org/ PMP ITIL RHCE MCTS More...	IT Skills Android Programming Data Modeling Objective C Programming Basic Python Programming Adobe Illustrator More...	Business Skills Advertising Techniques Business Accounting Basics Business Strategy Human Resource Management Marketing Basics More...
Soft Skills Body Language People Skills Public Speaking Persuasion Job Hunting And Resumes More...	Vocabulary GRE Vocab SAT Vocab TOEFL Essential Vocab Basic English Words For All Global Words You Should Know Business English More...	Languages AP German Vocab AP Latin Vocab SAT Subject Test: French Italian Survival Norwegian Survival More...	Engineering Audio Engineering Computer Science Engineering Aerospace Engineering Chemical Engineering Structural Engineering More...
Health Sciences Basic Nursing Skills Health Science Language Fundamentals Veterinary Technology Medical Language Cardiology Clinical Surgery More...	English Grammar Fundamentals Literary And Rhetorical Vocab Elements Of Style Vocab Introduction To English Major Complete Advanced Sentences Literature Homonyms More...	Math Algebra Formulas Basic Arithmetic: Measurements Metric Conversions Geometric Properties Important Math Facts Number Sense Vocab Business Math More...	Other Major Subjects Science Economics History Law Performing-arts Cooking Logic & Reasoning Trivia

Test your basic knowledge |

USMLE Step 1 Prep

Can you answer 50 questions in 15 minutes?

Let me suggest you:

Browse all subjects

Browse all tests

Most popular tests

Major Subjects

Tests & Exams

Certifications

IT Skills

Business Skills

Soft Skills

Vocabulary

Languages

Engineering

Health Sciences

English

Math

Other Major Subjects

Browse all subjects

Browse all tests

Most popular tests