Test your basic knowledge |

USMLE Step 1 Prep

Subjects : health-sciences, usmle-step-1

Instructions:

Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can study here.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. What transports iron in the blood?
Transferrin
Staphylococcus
Arginine
Class IV

2. Name the product or products of arachidonic acid: x Pain and fever
Huntington disease
Borrelia recurrentis
Arch of the aorta
PGE2

3. What is the only neuroglial cell of mesodermal origin?
DNA polymerase I
Arthroconidia with hyphae
Microglia. All others are neuroectodermal derivatives.
Pancreas and colon

4. What testicular tumor of infancy is characterized by elevated - fetoprotein levels and Schiller - Duval bodies?
Yolk sac tumor
3 to 4 days
Bender Visual Motor Gestalt Test
Baseline apical intrapleural pressure is -10 cm H2O (more negative than the mean) resulting in a force to expand the alveoli.

5. What is the central issue regarding the Roe vs. Wade decision (legalization of abortion)?
Cytokine. If a cytokine affects another class of leukocytes - it is called an interleukin.
Kartagener's syndrome (also known as immotile cilia syndrome) -------------------------------------------------------------------------------
Megaloblasts
The patient decides about the health care she does or does not get even if it harms the fetus. This also means she can refuse blood transfusions even if it harms the fetus.

6. What type of peptic ulcer disease is characterized by the onset of burning epigastric pain immediately after eating?
Neisseria meningitides
Variable ratio If it is based on time - it is an interval - and if it is based on the number of responses - it is a ratio.
Krukenberg tumor
Gastric ulcer

7. Unconsciously forgetting(forgetting that you forgot something!)
Repression
Degenerates
The submandibular ganglion. (Submandibular ganglion innervates the submandibular gland; easy enough.)
Adenine and guanine

8. What determines the plasma level at steady state?
Posterior chamber
The rate of infusion
Chromosome 4p
IgA

9. Name the cancer associated with the following tumor markers. (Some may have more than one answer.) x Beta - hCG
Permanent
Choriocarcinomas and trophoblastic tumors
Initiate and manage gross skeletal muscle movement control
Tip of the loop of Henle (1200 mOsm/L)

10. The closure of what valve indicates the beginning of isovolumetric contraction?
Mitral valve closure indicates the termination of the ventricular filling phase and beginning of isovolumetric contraction.
Ganciclovir
Superior olivary nucleus
Medial midbrain (Weber's) syndrome

11. If the pH is low with increased CO2 levels and decreased HCO3- levels - What is the acid - base disturbance?
Th1; they are also responsible for delayed - type hypersensitivity (type IV)
Mesangial macrophages
Combined metabolic and respiratory acidosis
Because it is the largest vessel and has the highest velocity in systemic circulation

12. What is the reservoir for the togavirus?
Ergosterol
Prolactin
Birds
Muscle spindles

13. What Staphylococcus aureus protein inhibits phagocytosis?
Propionic acid
Chromosome 9 - 22 (Philadelphia chromosome)
Protein A
Common peroneal nerve

14. The DSM- IV- TR is scored on the basis of five axes of diagnosis. In What axis would you place x Psychosocial and environmental problems (stressors)?
Neisseria gonorrhoeae
Axis IV
1. Picornavirus 2. Calicivirus 3. Reovirus (Remember PCR)
Ligament of Treitz

15. What are the four functions of saliva?
Ag - Ab binding
1. Provide antibacterial action 2. Lubricate 3. Begin CHO digestion 4. Begin fat digestion
Howell - Jolly bodies
Cancer

16. The ophthalmic artery is a branch of what vessel?
Internal carotid artery
Chronic rejection
IL-3 (3 face down is an M)
5' deiodinase

17. What is the most common one? - Sites for abdominal aorta aneurysm
Hematoxylin
Between the renal arteries and at the bifurcation of the abdominal aorta
Ovarian cancer
Decreases

18. What herpes virus is associated with Kaposi sarcoma?
1. Cefotetan 2. Cefoxitin 3. Ceftizoxime
Rotavirus
X- linked recessive
HHV 8

19. Can committed mentally ill patients refuse medical treatment?
Seasonal affective disorder (treat with bright light therapy)
All (nearly 15-20 times the normal risk)
Yes. The only civil liberty they lose is the freedom to come and go as they please.
Malpighian layer (made up of the stratum basale and stratum spinosum)

20. What hormone can be affected by dopamine release in the tuberoinfundibular pathway?
Paget disease (osteitis deformans)
Edward syndrome (trisomy 18)
In the tuberoinfundibular pathway - dopamine release will decrease prolactin release - Which is why dopamine agonists are used in the treaatment of hyperprolactinemic states.
Cytochrome a/a3

21. What organelle is responsible for ribosomal RNA synthesis?
Nucleolus. Ribosomal assembly also takes place in the nucleolus.
Squamous cell carcinoma of the lung
Lac repressor protein
Monosodium urate crystals

22. What embryonic week sees the formation of the notochord and the neural tube?
Zero - order elimination
K1 capsule
Unstable (crescendo) angina
Third week

23. What is the name of the B cell - rich area in the lymph node?
Posterior compartment of the leg - tibial nerve
Primary follicle of the cortex
Isocitrate dehydrogenase - a - ketoglutarate dehydrogenase - and malate dehydrogenase
antiemetic

24. What is the term for hypoperfusion of an area involving only the inner layers?
Aminoacyl - tRNA synthetase - which uses 2 ATPs for this reaction.
Mural infarct
Postinfectious GN
Posterior chamber

25. What is the most common opportunistic infection of the CNS in HIV?
gamma and delta chains
Selection bias
Toxoplasmosis
Brain - spleen - and kidney

26. What ocular muscle x Abducts the eyeball and is involved in horizontal conjugate gaze?
Anhedonia
Resorb CSF into the blood
With an increased rate of breathing the total ventilation is greater than the alveolar ventilation. Rapid - shallow breathing increases dead space ventilation with little change in alveolar ventilation. (This is hypoventilation).
Lateral rectus (CN VI) (LR6 SO4)3

27. What type of bias is it when the information is distorted because of the way it is gathered?
ELISA test
Measurement bias
Hypothyroidism. (TSH levels must be monitored.)
The thalamus (I like to think of the thalamus as the executive secretary for the cerebral cortex. All information destined for the cortex has to go through the thalamus.)

28. What drug blocks glucose uptake - leading to decreased formation of ATP and resulting in immobilization of the parasite?
Primary erectile disorder
Albendazole
Ratio scale
Diethylcarbamazine

29. Why is O2 content depressed in anemic patients?
Thymine
Anemic patients have a depressed O2 content because of the reduced concentration of Hgb in the blood. As for polycythemic patients - their O2 content is increased because of the excess Hgb concentrations.
Lead
Estrogen can result in a hypercoagulable state because of the decrease in AT III and increase in factors II - VII - IX - and X.

30. Does T3 or T4 have a greater affinity for its nuclear receptor?
A patent processus vaginalis
Musculocutaneous nerve
Gastric ulcer
T3 has a greater affinity for the nuclear receptor and therefore is considered the active form.

31. What five pathways use SAM (S- adenosylmethionine) as the methyl donor?
1. Epinephrine synthesis 2. Phosphatidyl choline 3. Creatine 4. Methylation of cytosine 5. N- methyl cap of mRNA
The tensor veli palatine is innervated by the mandibular division of the trigeminal nerve; all others are innervated by CN X.
1. Nails 2. Hair 3. Sweat glands (both apocrine and sebaceous)
Peyer's patch

32. Which direction does the uvula deviate in a left vagus nerve lesion?
Shaping (successive approximation)
ELISA is used as a screening test because it is very sensitive; Western blot is used as a confirmatory test because it detects antibodies (protein) to the HIV virus.
A left CN X lesion results in the uvula deviating to the right. (Uvula points away from the affected side.)
Chromosome 11 - 22

33. Being college educated increases a man's risk of having...
HMG- CoA reductase
Closure of the aortic valve indicates the termination of the ejection phase and the beginning of the isovolumetric relaxation phase of the cardiac cycle.
premature ejaculation
M- cells

34. What is the rate - limiting enzyme of glycogen synthesis?
NADPH oxidase
Glycogen synthase
C5a
Phallic stage (4-6 years)

35. Name the B- cell CD marker: x Required for class switching signals from T cells
Dihydrofolate reductase
Histidine
CD40
As flow increases - the urine becomes more dilute because of decreased time for H2O reabsorption.

36. What three structures are in contact with the left colic flexure? With the right colic flexure?
The tsetse fly
Left: stomach - spleen - and left kidney; right: liver - duodenum - and right kidney
Circumvallate papillae
Meningococcus grows on chocolate agar - and Gonococcus grows on Thayer - Martin medium.

37. How many ATPs are hydrolyzed every time a skeletal muscle cross - bridge completes a single cycle?
Reovirus
One - and it provides the energy for mechanical contraction.
Decreasing potassium conductance - which results in increased excitability
Series circuit

38. What is the most common one? - Bone tumor
Deferoxamine - penicillamine
Axis II
Third week; they are derived from the wall of the yolk sac.
Metastatic

39. What is the term for flexion of the PIP and extension of the DIP joints seen in rheumatoid arthritis?
The rate of infusion
Teeth grinding is associated with stage 2 sleep.
Boutonni
Stable

40. What is the first human disease successfully treated with gene therapy?
Rho (D) immune globulin (RhoGAM) - an anti - RhD IgG antibody - prevents generation of RhD- specific memory B cells in the mother.
Gaucher disease
Squamous cell carcinoma (skin - lung) and angiosarcoma of the liver
Adenosine deaminase (ADA) deficiency

41. Ensures emancipation.
Dopamine levels rise with waking; dopamine is associated with wakefulness.
Functional residual capacity (FRC)
Pregnancy
Hypervariable region (three per light chain; three per heavy chain)

42. What is the term for precipitation of calcium phosphate in dying or necrotic tissue?
Courvoisier's law
The lateral vestibular nucleus
2 and 5HT3 receptors
Dystrophic calcification

43. What is the only drug that does not have an intoxication?
Herpes virus
Stratified squamous nonkeratinized epithelium - which has cilia that beat toward the oropharynx.
Transference. When it is from the physician to the patient it is called countertransference.
Nicotine (but it sure has a nasty withdrawal!)

44. What is the pentad of TTP?

Warning: Invalid argument supplied for foreach() in /var/www/html/basicversity.com/show_quiz.php on line 183

45. The opening of what valve indicates the termination of isovolumetric relaxation phase of the cardiac cycle?
Both are AR with conjugated hyperbilirubinemia - but Dubin - Johnson syndrome is differentiated from Rotor by the black pigmentation of the liver.
Opening of the mitral valve indicates the termination of the isovolumetric relaxation phase and the beginning of the ventricular filling phase.
Barbiturate overdose and benzodiazepine withdrawal carry the highest mortality rates.
IgA deficiency; patients commonly present with recurrent sinopulmonary infections and GI disturbances.

46. How many ATPs are produced from cytoplasmic NADH oxidation using the malate shuttle?
3 ATPs by oxidative phosphorylation
A decrease in cutaneous blood flow results from constriction of the arterioles - and decreased cutaneous blood volume results from constriction of the venous plexus.
Loose association
Total ventilation (minute ventilation or minute volume)

47. What is the amount in liters and percent body weight for the following compartments? - Vascular fluid
Eosin
common variable hypogammaglobinemia
4.7 L - 5% of body weight
ELISA screens and Western blot confirms the diagnosis.

48. What foci of fibrinoid necrosis are surrounded by lymphocytes and macrophages throughout all the layers of the heart?
HPV
MEN III (or IIb)
Aschoff bodies of rheumatic fever
Terminal bronchioles. (No gas exchange occurs here.)

49. Name the type of necrosis - Soft - friable - cottage - cheese appearing; characteristically seen in TB
Epinephrine
Nasal polyps - rhinitis - and aspirin hypersensitivity
Transient ischemic attack
Caseous necrosis

50. Which fungus is found worldwide on plants - is a cigar - shaped yeast in tissue form - and results in rose gardener's disease?
Sporothrix schenckii
Chromosome 15
The right gonadal vein drains into the inferior vena cava directly - and the left gonadal vein drains into the left renal vein.
Myasthenia gravis