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USMLE Step 1 Prep

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What phase of the cell cycle are the following antineoplastic agents specific for? - Paclitaxel






2. Name the most common one - Chromosomal disorder






3. What forms of fatty acids are absorbed from the small intestine mucosa by simple diffusion?






4. What CNs are affected if there is a lesion in x The upper pons?






5. What mast cell mediator is a chemotactic agent?






6. Name the aphasia based on these characteristics: x Both Broca's and Wernicke's areas damaged by lesion in the presylvian speech area; trouble repeating statements; poor comprehension with telegraphic speech






7. If a mother delivers a Rho - positive baby - she should receive...






8. What bone disorder is characterized by brown tumors - bone pain - deformities - and fractures due to excessive PTH?






9. Name the DNA virus: x Partially dsDNA circular; enveloped; virion - associated polymerases; has RNA intermediate; replicates in the nucleus






10. What pathophysiologic disorder is characterized by the following changes in cortisol and ACTH? - Cortisol increased - ACTH decreased






11. What two AAs have a pKa of 4?






12. Name the insulin preparation based on the peak effect and duration of action - Peak - 0.5 to 3 hours; duration - 5 to 7 hours






13. Which drug is used to treat respiratory depression associated with an overdose of opioids?






14. Name the macrophage based on its location: x Liver macrophages






15. What disorder is due to a deficiency in tyrosinase?






16. What somatoform disorder is described as x Preoccupied with illness or death - persisting despite reassurance - lasting longer than 6 months?

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17. What three substances stimulate parietal cells?






18. What is the most common one? - Organism associated with mastitis






19. What bonds are broken by endonucleases?

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20. What phase of the cell cycle are the following antineoplastic agents specific for? - Cytarabine






21. What structure of a protein describes the interaction among subunits?






22. What is the most common one? - Form of necrosis






23. Name the cluster B personality disorder: x Colorful - dramatic - extroverted - seductive - and unable to hold long - term relationships






24. What Brodmann area is associated with x Primary visual cortex?






25. What is the first formal IQ test used today for children aged 2 to 18?






26. What thyroid enzyme is needed for oxidation of I- to I'?






27. Which class of antiarrhythmics are potassium channel blockers?






28. What three structures are in contact with the left colic flexure? With the right colic flexure?






29. What antiviral agent for ganciclovir - resistant infections has limited utility because of its nephrotoxic side effect?






30. What DNA excision and repair enzyme is deficient in patients with xeroderma pigmentosum?






31. Name the area of the cerebral cortex with the function described: x Initiation and control of movements






32. What CNS developmental abnormality is associated with downward displacement of the cerebellar vermis and medulla compressing the fourth ventricle and leading to obstructive hydrocephalus?






33. Would a G- C or an A- T rich dsDNA sequence have a higher melting point? Why?






34. What virus is associated with progressive multifocal leukoencephalopathy?






35. What term describes the inability to recall personal information - commonly associated with trauma?






36. All spore formers are...






37. When does cortisol secretion peak?






38. What three organs are responsible for peripheral conversion of T4 to T3?

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39. Are antineoplastic agents that work on actively proliferating cells schedule or dose dependent?






40. What foramen must be traversed for entry into the lesser peritoneal sac?






41. What ocular muscle x Depresses and adducts the eyeball?






42. What type of collagen is abnormal in patients with osteogenesis imperfecta?






43. Name the cancer associated with the following tumor markers. (Some may have more than one answer.) x PSA and prostatic acid phosphatase






44. Is a subdural hematoma an arterial or venous bleed?






45. At what stage of psychosexual development (according to Freud) do children fear castration?






46. Of what serotonin receptor is sumatriptan an agonist?






47. Which three factors cause the release of epinephrine from the adrenal medulla?






48. Name these mature defense mechanisms: x Helping others without expecting any return






49. Name the thalamic nucleus based on its input and output - Input from the amygdala - prefrontal cortex - and temporal lobe; output to the prefrontal lobe and the cingulated gyrus






50. Calf pseudohypertrophy