Test your basic knowledge |

USMLE Step 1 Prep

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What DNA virus is associated with heterophile - negative mononucleosis?






2. Damage to what nerve will give you winged scapula?






3. Orphan Annie cells






4. How many pairs of spinal nerves are associated with x Cervical vertebrae?






5. Which two antipsychotic drugs create a high risk for developing extrapyramidal syndrome (EPS) side effects?






6. What area of the hypothalamus is the feeding center?






7. Which subset of MEN syndrome is associated with the following? - Medullary carcinoma of the thyroid - pheochromocytoma - and parathyroid adenomas (or hyperplasia)






8. What fungus is seen as colored cauliflower lesions?






9. What is the drug of choice for steroid - induced osteoporosis?






10. Neurofibrillary tangles






11. What lower extremity nerve is described by the following motor loss? - Loss of abduction of the hip resulting in Trendelenburg gait






12. Is the coding or the template strand of DNA identical to mRNA (excluding the T/U difference)?






13. What happens to free hormone levels when the liver decreases production and release of binding proteins?






14. Which gram - negative diplococcus ferments maltose?






15. Name the most common cause - Dementia in persons aged 60 to 90 years






16. What blotting technique uses the following for analysis? - Protein






17. Inhibits glucose uptake in skeletal muscle.






18. What is the term for a schizophrenic episode lasting longer than 30 days with full return to former functioning capacity?






19. Starry sky pattern






20. What is the name of the exotoxin Shigella dysenteriae produces - which interferes with the 60S ribosomal subunit and results in eukaryotic protein synthesis inhibition?






21. What naturally occurring substances mimic the effects of opioids?






22. Bloody tap on lumbar puncture






23. What are the most common causes of osteomyelitis x Overall?






24. At what vertebral levels does the aortic arch begin and end?






25. What AD disease involves hyperkeratosis of the palms and soles in association with esophageal carcinoma?






26. The closure of what valve indicates the beginning of the isovolumetric relaxation phase of the cardiac cycle?






27. What is the main type of cell involved in cellular immunity?






28. What are the two absolute requirements for the cytochrome P450 enzyme system?






29. Regarding muscle mechanics - How is passive tension produced?






30. Name the Hgb - O2 binding site based on the following information: x Remains attached under most physiologic conditions






31. In What trimester is the fetus most vulnerable to congenital rubella syndrome?






32. What CN is associated with the x Third pharyngeal arch?






33. Insulin - induced hypoglycemia is the most reliable (by far not the safest) test For what hormone deficiency?






34. Two weeks after her son has a throat infection - a mother takes the boy to the ER because he has fever - malaise - HTN - dark urine - and periorbital edema. What is your diagnosis?






35. What is the term for the difference between systolic and diastolic pressures?






36. Name the type of necrosis - Seen as dead tissue with coagulative necrosis






37. What are effects of PTH in the kidney?






38. Name the associated chromosome - Cri - du - chat






39. What is the term for a RBC that has a peripheral rim of Hgb with a dark central Hgb - containing area?






40. How are pulse pressure and compliance related?






41. Is Dubin - Johnson or Rotor syndrome associated with black pigmentation of the liver?






42. All Proteus species are...






43. Is increased in 21-Beta- hydroxylase deficiency.






44. In an adrenergic nerve terminal - Where is dopamine converted to NE? By what enzyme?






45. What cardiac reflex is characterized by stretch receptors in the right atrium - afferent and efferent limbs via the vagus nerve - and increased stretch leading to an increase in heart rate via inhibition of parasympathetic stimulation?






46. What chromosome codes for HLA gene products?






47. Does the zygote divide mitotically or meiotically?






48. What leukemia is characterized by Philadelphia chromosomal translocation (9;22); massive splenomegaly; peripheral leukocytosis (commonly > 100 - 00); decreased LAP levels; and nonspecific symptoms of fatigue - malaise - weight loss - and anorexia?






49. What general pattern of sleep is described by slowing of EEG rhythms (high voltage and slower synchronization) - muscle contractions - and lack of eye movement or mental activity?






50. What component of the inner ear x Contains endolymph and responds to head turning and movement?