Test your basic knowledge |

USMLE Step 1 Prep

Subjects : health-sciences, usmle-step-1

Instructions:

Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can study here.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Which organisms have polycistronic mRNA?
MEN III (or IIb)
Minor
Catechol - O- methyl transferase (COMT)
Prokaryotes. Polycistronic and prokaryotes both start with P.

2. What is the site of action of cholera toxin?
GP Ib
Voltage - gated sodium channel
Cholera toxin irreversibly activates the cAMP- dependent chloride pumps of the small and large intestine - producing a large volume of chloride - rich diarrhea.
Theca cell

3. Is there a shift in p50 values with anemia? Polycythemia?
Skin - liver - and kidneys
Stibogluconate
The p50 value does not change in either anemia or polycythemia; the main change is the carrying capacity of the blood.
Duchenne muscular dystrophy

4. Which gram - positive bacteria infection of infancy is associated with ingestion of honey?
Primary hypothyroidism (Low T4 has a decreased negative feedback loop - resulting in both the hypothalamus and the anterior pituitary gland to increase TRH and TSH release - respectively.)
Foramen of Monro
robenecid - a uricosuric agent
Clostridium botulinum

5. What type of fiber or fibers are carried in (answer motor - sensory - or both) x Dorsal root ganglion?
Reject it
Sensory
Stereocilia
Coronavirus

6. What form of hemophilia is X- linked recessive and due to a deficiency in factor VIII?
IgE. It attaches via receptor for the Fc region of the heavy epsilon chain
Sensory
Decreases
Hemophilia A

7. What are the three most common sites for left - sided heart embolisms to metastasize?
The p50 value does not change in either anemia or polycythemia; the main change is the carrying capacity of the blood.
Small to medium - sized cerebral vessels
Brain - spleen - and kidney
Abs to HBsAg

8. What pathophysiologic disorder is characterized by the following changes in cortisol and ACTH? - Cortisol decreased - ACTH increased

Warning: Invalid argument supplied for foreach() in /var/www/html/basicversity.com/show_quiz.php on line 183

9. Should you refer a patient to a form of folk medicine even if you don't believe in it?

Warning: Invalid argument supplied for foreach() in /var/www/html/basicversity.com/show_quiz.php on line 183

10. What is the term for pigmented iris hamartomas seen in patients with neurofibromatosis type 1?
100%; the percentage of blood flow through the pulmonary and systemic circulations are equal.
Lisch nodules
A patent processus vaginalis
Raynaud's phenomenon

11. What are the two ways to leave the prevalence pot?
Recovery and death
APocrinE glands (APES is my memory aid) Axilla - Areola - and Anus all begin with A. APES are hairy (associated with hair follicles). They smell (odor production) - and if confronted by an APE - your Adrenergic nervous system would be firing (innerva
Median nerve
Transvestite fetishism

12. What cell transports IgA - is secreted by plasma cells - and is in Peyer's patches to the gastrointestinal lumen?
Itraconazole
Indirect hernia passes in the inguinal canal; a direct hernia passes directly through Hesselbach's triangle.
Superior gluteal nerve
M- cells

13. What forms of fatty acids are absorbed from the small intestine mucosa by simple diffusion?
Short - chain fatty acids
robenecid - a uricosuric agent
Secondary erectile disorder (Male erectile disorder is the same as impotence.)
Serratus anterior

14. In a parallel circuit - what happens to resistance when a resistor is added in parallel
1. Streptomycin 2. Gentamicin 3. Tobramycin
Cystic fibrosis
Resistance decreases as resistors are added in parallel.
Bactericidal

15. What are the three glycogenic organs?
Antisocial personality
Pseudomonas aeruginosa
Th1; they are also responsible for delayed - type hypersensitivity (type IV)
Liver - kidney - and GI epithelium

16. What is the primary predisposing factor for vascular dementia?
Hypertension
Serocystadenocarcinoma
Cholesterolosis
Increase in ECF osmolarity means a in decrease in ICF osmolarity - so cells shrink.

17. What is the name of the postganglionic parasympathetic ganglion that innervates x The lacrimal gland and oral and nasal mucosa?
Xanthine - hypoxanthine - theophylline - theobromine - caffeine - and uric acid are all purines.
Pterygopalatine ganglion (I remember this as the only ganglion left.)
The hairpin loop made by reverse transcriptase at the 3' end of the first strand is the primer.
Rigors - leukopenia - decrease in blood pressure - and increase in temperature

18. Which bacteria are associated with the following pigment production? - Black - gray pigmentation
Corynebacterium diphtheriae
Hypothyroidism. (TSH levels must be monitored.)
Parental assignment and culture (not biology)
Foods rich in tyramine (e.g. - cheese - dried fish - sauerkraut - chocolate - avocados - and red wine) should be avoided. Hypertensive crisis occurs when tyramine and MAOIs are mixed.

19. Name these anxiety defense mechanisms: x Separating oneself from the experience. The facts are accepted but the form is changed for protection.
Paget disease of the breast
Rigors - leukopenia - decrease in blood pressure - and increase in temperature
Dissociation
In the first and second bronchi

20. What is the name of the T cell - rich area of the spleen?
Subarachnoid hematoma
Vesicular stomatitis virus
Niclosamide
PALS (Parietolateral lymphocytic sheath)

21. What is a plasma cell's life expectancy?
1. Dorsal scapular 2. Suprascapular 3. Long thoracic 4. Nerve to subclavius
Clozapine
The interposed nucleus
7 to 14 days

22. What is the titratable acid form of H+ in the urine?
Middle meningeal artery
Ligament of Treitz
Renal plasma flow (decrease flow - increase FF)
H2PO4- (dihydrogen phosphate)

23. Name the hypochromic microcytic anemia based on the following laboratory values - Increased iron - decreased TIBC - increased percent saturation - increased ferritin
The sensory limb is via CN IX - and the motor limb is from CN X.
Protein A
Sideroblastic anemia
Transitional cell carcinoma

24. What GI pathology can be caused by a patient taking clindamycin or lincomycin or by Clostridium difficile - ischemia - Staphylococcus - Shigella - or Candida infection?
Pseudomembranous colitis
CD40
1. Sustained release 2. IV drip 3. Phenytoin 4. Alcohol 5. Aspirin toxicity
Neisseria meningitidis

25. What happens to flow and pressure in capillaries with arteriolar dilation? Arteriolar constriction?
Mitosis
Avidity. There is a positive correlation between valence numbers and avidity.
CD4
Capillary flow and pressure increase with arteriolar dilation and decrease with arteriolar constriction.

26. What AD disorder is characterized by degeneration of GABA neurons in the caudate nucleus resulting in atrophy - chorea - dementia - and personality changes?
Red blood cell distribution width index (RDW)
Huntington disease
Parietal cells (Remember - they secrete HCl - too.)
Leiomyoma

27. Name the antidote - Digoxin
Antidigoxin Fab fragments
HPV serotypes 1 and 4
Are inactivated vaccines available in the United States
1 day prior to ovulation

28. What CN is associated with the x First pharyngeal arch?
They are all formed by the fifth month of fetal life.
Left atrial myxoma
CN V
Isocitrate dehydrogenase - a - ketoglutarate dehydrogenase - and malate dehydrogenase

29. Is masturbation considered an abnormal sexual practice?
Negative
Embolic
No. It is abnormal only if it interferes with normal sexual or occupational function.
Seminoma

30. What tumor constitutes 40% of testicular tumors in children?
1. Fructokinase 2. Glucokinase 3. Glycerol kinase 4. PEPCK 5. Pyruvate carboxylase 6. Galactokinase 7. Fructose -1 - 6- bisphosphatase 8. Glucose -6- phosphatase
Teratoma
Edinger - Westphal nucleus (via CN III)
Negative selection. This helps to prevent autoimmune diseases.

31. What happens to O2 affinity with a decrease in p50?
Ligamentum arteriosum
ELISA. It detects anti - p24 IgG.
Proencephalon diencephalon derivative
O2 affinity increases with a decrease in the p50 - making O2 more difficult to remove from the Hgb molecule.

32. Name the most common type or cause - Cushing syndrome
Brain abscess
Surface tension; in the alveoli - it is a force that acts to collapse the lung.
Methanol (wood alcohol)
Pituitary adenoma

33. What is the function of the basal ganglia?
'Lady between two Majors': latissimus dorsi - pectoralis major - and teres major
RNA polymerase I
Initiate and manage gross skeletal muscle movement control
Mesothelioma and bronchogenic carcinoma

34. When the results of a test are compared to findings for a normative group - what form of reference does the objective test use?
Confabulation; it is commonly seen in Korsakoff's syndrome.
Ascending limb
Norm reference (i.e. - 75% of the students in the class will pass)
First - pass metabolism and acid lability

35. What is the most common one? - Melanoma in dark - skinned persons
Selenium (Se)
Schatzki ring
Acral - lentiginous melanoma
Eosin

36. Name the type of necrosis - Due to lipase activity and has a chalky white appearance
No - it is not a mandatory reportable offense (if you can believe it). Child and elderly abuse are mandatory reportable offenses.
Generalized anxiety disorder
Fat necrosis
Squamous cell carcinoma

37. What are the three surrogate criteria?

Warning: Invalid argument supplied for foreach() in /var/www/html/basicversity.com/show_quiz.php on line 183

38. What virus is associated with progressive multifocal leukoencephalopathy?
The alveoli at the base are small and very compliant - so there is a large change in their size and volume and therefore a high level of alveolar ventilation.
Chromosome 4p
Zero - order elimination
JC virus

39. What is the effect of insulin on protein storage?
LTC4 and LTD4
Decreasing potassium conductance - which results in increased excitability
Insulin increases total body stores of protein - fat - and CHOs. When you think insulin - you think storage.
Metronidazole

40. What complex is needed for propionyl CoA carboxylase?
Biotin - ATP - and CO2
Microcytotoxic assay
LGB (think EYES)
Respiratory depression

41. Match the chromosome and haploid number with the stage of sperm development - spermatid - spermatocyte (primary or secondary) - spermatogonia (type A or B): x 46/2n (divide meiotically)
Oxazepam - temazepam - and lorazepam ( OTL - Outside The Liver)
Spermatogonia (type A)
Reliability (think of it as 'nice grouping' or 'precise')
H 2

42. If the P value is less than or equal to .05 - What do you do to the null hypothesis?
Reject it
Syncytiotrophoblast. (The cytotrophoblast gets incorporated into the syncytiotrophoblast.)
Myeloschisis All except occulta cause elevated - fetoprotein levels.
Thiabendazole

43. What are the two MCC of acute epididymitis in males? - Less than 35 years old
Chlamydia; gonorrhea is second (Remember - it is mandatory to report STDs to the CDC.)
BPH
Disorganized schizophrenia
Neisseria gonorrhoeae and Chlamydia trachomatis

44. Place in order from fastest to slowest the rate of gastric emptying for CHO - fat - liquids - and proteins.
Liquids - CHO - protein - fat
Enterohepatic cycling
VIPoma
Malignancy

45. What two Ags must be positive for a patient to have chronic active hepatitis?
The blood withdrawn is the unconditioned stimulus - inducing the unconditioned response (fainting). The needle is part of the blood - drawing procedure and is the conditioned stimulus (unconditioned and conditioned stimuli are paired) resulting in th
Finasteride
HBsAg and HBeAg
Free hormone levels remain constant - and the bound hormone level changes with a decrease in binding hormones.

46. What fungus is seen as colored cauliflower lesions?
Hepatic adenomas
Chromomycosis
HMP shunt
Iodine - resulting in congenital hypothyroidism

47. Name the associated chromosome - Down syndrome
X- linked dominant
Chromosome 21
Topoisomerase I (Relaxase)
Left homonymous hemianopsia

48. Do the PO2 peripheral chemoreceptors of the carotid body contribute to the normal drive for ventilation?
Monocytosis
NREM sleep. Night terrors are dreams that we are unable to recall.
Under normal resting conditions no - but they are strongly stimulated when PO2 arterial levels decrease to 50 to 60 mm Hg - resulting in increased ventilatory drive.
Propionibacterium acnes

49. What is the most common one? - Germ cell tumor in men
Seminoma
12 to 16 weeks (in response to mother's face)
Anterior tibial artery
Metabolic acidosis (summary: low pH - high H+ - and low HCO3-)

50. Name these immature defense mechanisms: x Taking others' beliefs - thoughts - and external stimuli and making them part of the self. (Hint: if it's done consciously - it is called imitation.)
Acting out
Trypsin
Introjection (a sports fan is a good example)
Systematic desensitization