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USMLE Step 1 Prep

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What oral hypoglycemic agent should be used with caution in patients with CHF because it causes lactic acidosis?






2. Name the cancer associated with the following tumor markers. (Some may have more than one answer.) x CA-19.9 and CEA






3. Which chromosome is associated with MHC genes?






4. What are the two reasons for megaloblastic anemia with elevated MCV?






5. Waxy casts






6. Name the valve abnormality based on the following criteria: x Systolic murmur - increased preload and afterload - decreased aortic pulse pressure and coronary blood flow






7. In which syndrome does a person present with intentionally produced physical ailments with the intent to assume the sick role?






8. What is the term to describe the increase in organ size due to the increase in cell size and function?






9. From What embryonic structure are the following structures derived? - The sinus venarum - coronary sinus - and the oblique vein of the left atrium






10. Where is tropocollagen aggregated to form a collagen fibril?






11. What liver enzyme - for triglyceride synthesis - converts glycerol to glycerol -3- phosphate?






12. Are the following conditions associated with a negative or positive nitrogen balance? - Starvation






13. What paraphilia is defined as x Deriving sexual pleasure from being abused or in pain?






14. Kayser - Fleischer rings






15. What pathology is associated with deposition of calcium pyrophosphate in patients older than 50 years?






16. What are the three main functions of surfactant?






17. What is the first Ag seen in an individual with hepatitis?






18. Name the macrophage based on its location: x Connective tissue macrophages






19. What is the name of the hypothesis you are trying to prove?






20. What are the two broad - spectrum penicillins?






21. Name the thalamic nucleus based on its input and output - Input from globus pallidus and substantia nigra; output to primary motor cortex






22. What muscles make up the rotator cuff?






23. What intrauterine deficiency leads to failure to thrive - mental retardation - motor incoordination - and stunted growth?






24. Name the area of the cerebral cortex affected by the description of the effects - symptoms - and results of the lesion - Apathy - poor grooming - poor ability to think abstractly - decreased drive - poor attention span (Hint: if the lesion is in the






25. What somatoform disorder is described as x Having a F:M ratio of 20:1 - onset before age 30 - and having 4 pains (2 gastrointestinal - 1 sexual - 1 neurologic)?






26. Name the thalamic nucleus based on its input and output - Input from globus pallidus and the cerebellum; output to the primary motor cortex






27. Irreversible ototoxicity is associated with which loop diuretic?






28. How does ventricular repolarization take place - base to apex or vice versa?






29. What are the pharmacologic effects seen sexually with x Neuroleptics?






30. Describe the organism based on the following information: x Alpha - Hemolytic Streptococcus; lysed by bile; sensitive to Optochin






31. Name the three postganglionic sympathetic ganglia that receive input from thoracic splanchnics.

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32. What are the two ways that nitrogen can enter into the urea cycle?






33. What are defined by Ag - binding specificity?






34. Name the thalamic nucleus based on its input and output - Input from the mammillary bodies via the mammillothalamic tract and the cingulated gyrus; output to the cingulated gyrus via the anterior limb of the internal capsule






35. Which hepatitis B serology markers






36. What is the term for the number of individuals who have an attribute or disease at a particular point in time?






37. Are the following major or minor Jones criteria of rheumatic fever? - Erythema marginatum






38. What nerve is associated with the following functions? - Innervation of the flexor carpi ulnaris - flexor digiti profundus (pinky and ring fingers) - and the intrinsic muscles of the hand






39. The duodenal - jejunal flexure is suspended from the posterior abdominal wall by what?






40. What type of fiber or fibers are carried in (answer motor - sensory - or both) x Ventral rami?






41. What is the name for the most prominent spinous process?






42. What papillae are responsible for sweet taste?






43. What is the titratable acid form of H+ in the urine?






44. Where are the LMN cell bodies of the corticospinal tract?






45. What pancreatic islet cell secretes somatostatin?






46. What is the only local anesthetic to produce vasoconstriction?






47. Has a sodium - conserving action in the distal colon.






48. What is the most common form of inherited dwarfism?






49. What enzyme is deficient in the following glycogen storage disease? - Hers' disease






50. What is the most common one? - Valve abnormality associated with rheumatic fever