Test your basic knowledge |

USMLE Step 1 Prep

Subjects : health-sciences, usmle-step-1

Instructions:

Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can study here.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Upon seeing negatively birefringent needle - shaped crystals from a joint aspiration of the great toe - what form of arthritis do you diagnose?
The death of a spouse. The higher the score - the greater the risk of developing an illness in the next 6 months.
Gout
Left colic - superior rectal - and sigmoidal arteries
Promotes systemic venous return into the chest and increases the caliber and volume of the pulmonary vessels

2. What fungus is seen as colored cauliflower lesions?
Chromomycosis
Myeloperoxidase
5- hydroxyindoleacetic acid (5- HIAA)
Affinity decreases; they are inversely proportional.

3. In a skeletal muscle fiber - the interior of the T- tubule is...
Extracellular
Transketolase and transaldolase. The reactions they catalyze are reversible.
4.7 L - 5% of body weight
IgG

4. What is the physiologic storage form of iron?
Ferritin
Glyceraldehyde dehydrogenase
Carbamoyl phosphate synthetase I
Hepatocytes lack the enzyme succinyl CoA acetoacetyl CoA transferase (thiophorase).

5. Name the most common type or cause - Pyogenic osteomyelitis
Sertoli cell
Leishmania donovani (kala azar is also known as visceral leishmaniasis)
Staphylococcus aureus
Cohort studies determine incidence and causality - not prevalence.

6. What neurotransmitter is presynaptically inhibited by reserpine and guanethidine?
Creutzfeldt - Jakob disease
NE
They are in ganglia in the PNS.
The p50 value does not change in either anemia or polycythemia; the main change is the carrying capacity of the blood.

7. Does physiologic splitting of the first heart sound occur during inspiration or expiration? Why?
Splitting of the first heart sound occurs during inspiration because of the increased output of the right ventricle - delaying the closure of the pulmonic valve.
Albinism
Pulmonary shunt (i.e. - pulmonary embolism)
Bruton X- linked hypogammaglobinemia. Tyrosine kinase deficiency leads to inadequate B cell maturation.

8. What is the term for the first 3 to 5 days of the female reproductive cycle?
Churg - Strauss syndrome
Menses. (Ovulation occurs 14 days before the beginning of menses.)
Anemic patients have a depressed O2 content because of the reduced concentration of Hgb in the blood. As for polycythemic patients - their O2 content is increased because of the excess Hgb concentrations.
Histamine

9. What pathophysiologic disorder is characterized by the following changes in cortisol and ACTH? - Cortisol increased - ACTH increased
Secondary hypercortisolism (pituitary)
Volume of distribution is decreased when a large percentage of drug is protein bound.
Arthroconidia with hyphae
Chromosome 9 - 22 (Philadelphia chromosome)

10. From What embryonic structure are the following structures derived? - The right and left ventricles
Primitive ventricle
Absolutely not. Diabetics who are given a Beta- blocker for an acute chest syndrome have significantly better outcomes than those who do not.
catalase - negative
(MA/CA) x 100 = IQ score - where MA = mental age and CA = chronological age

11. What determines the Vmax of skeletal muscle?

Warning: Invalid argument supplied for foreach() in /var/www/html/basicversity.com/show_quiz.php on line 183

12. Which PG is associated with maintaining a PDA?
Bender Visual Motor Gestalt Test
Atropine and 2- PAM (pralidoxime)
PGE and intrauterine or neonatal asphyxia maintain patency of the ductus arteriosus. Indomethacin - ACh - and catecholamines promote closure of the ductus arteriosus.
Bacillus anthracis

13. Name the type of necrosis - The most common form of necrosis; denatured and coagulated proteins in the cytoplasm
Fructose; both glucose and galactose are actively absorbed via secondary active transport.
Polycystic ovary disease (Stein - Leventhal syndrome)
Adrenal medulla
Coagulative necrosis

14. What antipsychotic movement disorder can occur at any time and is characterized by a subjective sense of discomfort that brings on restlessness - pacing - sitting down - and getting up?
Enteroendocrine (EE) cells; they also secrete secretin.
Paradoxic emboli most commonly enter the arteries through a patent septal defect in the heart.
Akathisia
The death of a spouse. The higher the score - the greater the risk of developing an illness in the next 6 months.

15. What are the three polymorphonuclear leukocytes? Be specific.
PTH increases Ca2+ reabsorption in the DCT of the kidney and decreases PO4- reabsorption in the PCT.
Shiga toxin (enterohemorrhagic Escherichia coli produces Vero toxin - Which is quite similar to shiga toxin)
Ischemic heart disease (MIs)
Neutrophils - eosinophils - and basophils

16. Which integrin mediates the adhesion to endothelial cells for migration in and out of the blood during an immune response?
Beta2- integrins
Levator palpebrae superioris
de Quervain thyroiditis
Birds

17. What is the only enzyme in the body that uses N-5- methyl folate?
Squamous cell carcinoma
Accuracy (think of it as all the trues - because they are the ones correctly identified)
Homocysteine methyl transferase
Mesencephalon

18. Increased urinary excretion of what substance is used to detect excess bone demineralization?
Minocycline
ydroxyproline
1. Conjunctivitis 2. Nongonococcal urethritis 3. Peripheral arthritis Can't see - can't wee - can't kick with your knee
Superoxide dismutase - glutathione peroxidase - catalase

19. In which form of emphysema - panacinar or centriacinar - is the effect worse in the apical segments of the upper lobes?
Serocystadenoma
Centriacinar worse in upper lobes; panacinar worse in base of lower lobes
G-6- PD deficiency
2 acetyl CoA per glucose - producing 12 ATPs per acetyl CoA - resulting in a total of 24 ATPs produced from glucose (via acetyl CoA) enter the TCA cycle

20. In what disease is there a genetic absence of UDP- glucuronate transferase - resulting in an increase in free unconjugated bilirubin?
Crigler - Najjar syndrome
NREM sleep. Night terrors are dreams that we are unable to recall.
Howell - Jolly bodies
Appendix (second is terminal ileum)

21. What hormone is necessary for normal GH secretion?
Normal thyroid hormones levels in the plasma are necessary for proper secretion of GH. Hypothyroid patients have decreased GH secretions.
Cryptococcus
Loss of hypotonic fluid (alcohol - diabetes insipidus - dehydration)
Preganglionic sympathetic neurons

22. Name the cancer associated with the following tumor markers. (Some may have more than one answer.) x Beta - hCG
It both begins and ends at T4 (sternal angle [of Louis]).
Increases Remember - the carotid sinus reflex attempts to compensate by increasing both TPR and heart rate. -------------------------------------------------------------------------------
Residual volume (RV)
Choriocarcinomas and trophoblastic tumors

23. What structure or structures cross the diaphragm at x T10 level?
Medial umbilical ligaments
Esophagus and esophageal nerve plexus (CN X) Remember: 1 at T8 - 2 at T10 - and 3 at T12
The outer cortex contains most of the germinal centers and therefore also most B cells.
Nearly 25% of patients taking lithium develop polyuria and polydipsia.

24. What is the term for precipitation of calcium phosphate in dying or necrotic tissue?
Eaton - Lambert syndrome
Dystrophic calcification
Intercellular adhesion molecule (ICAM) 1
Leydig cell tumor

25. What disorder is described as having x Conscious symptoms with conscious motivation?
Legionella
Malingering
Bcl -2
Accommodation

26. Which bacteria are associated with the following pigment production? - Yellow pigmentation
Insulin
Actinomyces israelii
Middle
Staphylococcus aureus

27. What five cofactors and coenzymes are required by pyruvate dehydrogenase?
Agglutination test
Since CO2 is 24 times as soluble as O2 - the rate at which CO2 is brought to the membrane determines its rate of exchange - making it perfusion - limited a gas. For O2 the more time it is in contact with the membrane - the more likely it will diffuse
Poxvirus replicates its DNA in the cytoplasm.
1. TTP 2. Lipoic acid 3. Coenzyme A from pantothenate 4. NAD(H) (from niacin or tryptophan) 5. FADH2 (from riboflavin)

28. How many ATPs per glucose are generated from glycolysis in RBCs?
RNA polymerase II
Stable
Allotypes
2 ATPs - because RBCs use only anaerobic metabolism.

29. What toxicities are caused by the following agents? - Halothane
Hepatitis - with or without necrosis
Increase in erythropoietin and increase in 2 - 3- BPG - also called 2 - 3- diphosphoglycerate (2 - 3- P2Gri) (increase in glycolysis)
Ascending limb
Ticlopidine or clopidogrel

30. What are the three sites where CSF can leave the ventricles and enter the subarachnoid space? (Name the lateral and the medial foramina.)
Gradient - time system
Positive predictive value
Parkinson's disease
Two Lateral foramina of Luschka and 1 Medial foramen of Monroe (L for Lateral and M for Medial)

31. What is the most common one? - Site of a cerebral infarct
Prophase of meiosis I (between 12th and 22nd week in utero)
Vitamin B12 deficiency and folate deficiency
Middle cerebral artery
Carbamazepine

32. Which anticonvulsant is also used in the treatment of bipolar disorder and for migraine headaches?
Prostatic carcinoma
Valproic acid
Suprachiasmatic nucleus
Ego dystonic

33. Which phenotype of osteogenesis imperfecta is incompatible with life?
Aspiration
Yes - because they both activate the BZ1- receptors - which can be reversed by flumazenil.
Primary sclerosing cholangitis
Type II

34. What syndrome is characterized by dynein arm abnormality resulting in chronic sinusitis - recurrent pulmonary infections - and infertility?

Warning: Invalid argument supplied for foreach() in /var/www/html/basicversity.com/show_quiz.php on line 183

35. Name the MCC of death - In diabetic individuals
Somatotrophins are stimulated by IGF-1 - and they inhibit GH secretion. GHRH stimulates GH secretion.
Tertiary hypothyroidism/hypothalamic (Low TRH causes all the rest to be decreased because of decreased stimulation.)
Decreases
MI

36. What cytokine do Th1 cells secrete to inhibit Th2 cell function?
INF- gamma
Stage 4
Foramen of Monro
Thiogalactoside transacetylase

37. What is the most common one? - Site of ischemia in the GI tract
Thyroid hormones
Meningocele All except occulta cause elevated - fetoprotein levels.
Splenic flexure
Beta- Endorphin

38. What form of continuous DNA - used in cloning - has no introns or regulatory elements?
The second pharyngeal pouch and groove
Urinary 17- OH steroids
Rapid cycling bipolar disorder
cDNA - when it is made from mRNA

39. Name the most common type or cause - Cellular injury
5- hydroxyindoleacetic acid (5- HIAA)
Hypoxia
CMV - Toxoplasma gondii - and Listeria
Carbidopa and benserazide

40. What is the term for Candida infection of the oral mucosa?
Thrush
Between the renal arteries and at the bifurcation of the abdominal aorta
Plasmodium malariae
Valence

41. What toxin ADP- ribosylates via Gi to increase cAMP?
Pertussis toxin
Budd - Chiari syndrome
5- hydroxyindoleacetic acid (5- HIAA)
Homicide. It is also the leading cause of death in black females aged 15 to 24.

42. Which IgG cannot activate complement?
Bisphosphonates
IgG4
CD8
The sensory component is through the superior laryngeal nerve - and the motor limb is via the recurrent laryngeal nerve.

43. Do alpha - or gamma - motor neurons innervate extrafusal muscle fibers?
alpha - Motor neurons innervate extrafusal muscle fibers (a motor unit) - whereas gamma - motor neurons innervate intrafusal muscle fibers.
Primary biliary cirrhosis
Follicular lymphoma
Chromium (Cr)

44. What right - to - left shunt occurs when the aorta opens into the right ventricle and the pulmonary trunk opens into the left ventricle?
Stratified squamous nonkeratinized epithelium - which has cilia that beat toward the oropharynx.
Transposition of the great vessels arises from a failure of the aorticopulmonary septum to grow in a spiral.
Serocystadenocarcinoma
Carcinoid tumor

45. What are the two ways to leave the prevalence pot?
Recovery and death
positive correlation
Cushing's disease (pituitary) has elevated ACTH and cortisol suppression with dexamethasone - whereas Cushing's syndrome (adrenal adenoma) has decreased ACTH and no cortisol suppression with dexamethasone.
LGB (think EYES)

46. What are the five pieces of information considered necessary for fully informed consent?

Warning: Invalid argument supplied for foreach() in /var/www/html/basicversity.com/show_quiz.php on line 183

47. What is the term for the number of Ag - binding sites on an Ig?
HMG CoA synthase
Valence
Accessory nucleus
Stapedius muscle

48. What organism is associated with megaloblastic anemia?
Spironolactone (binds to aldosterone receptors)
At least 30% blast in the bone marrow
McArdle's syndrome
Diphyllobothrium latum

49. Which group of antihypertensive agents best decreases left ventricular hypertrophy?
No - therapeutic indices can tell which drug is safer - not more toxic.
Squamous cell carcinoma
Subscapularis
Thiazide diuretics

50. What causes transcription to stop in eukaryotes?
Superior and anterior
The poly(A) site on the DNA
Ventral posterolateral nucleus
Radial nerve and the profunda brachii artery

Sorry!:) No result found.

Can you answer 50 questions in 15 minutes?

Major Subjects
Tests & Exams AP CLEP DSST GRE SAT GMAT	Certifications CISSP go to https://www.isc2.org/ PMP ITIL RHCE MCTS More...	IT Skills Android Programming Data Modeling Objective C Programming Basic Python Programming Adobe Illustrator More...	Business Skills Advertising Techniques Business Accounting Basics Business Strategy Human Resource Management Marketing Basics More...
Soft Skills Body Language People Skills Public Speaking Persuasion Job Hunting And Resumes More...	Vocabulary GRE Vocab SAT Vocab TOEFL Essential Vocab Basic English Words For All Global Words You Should Know Business English More...	Languages AP German Vocab AP Latin Vocab SAT Subject Test: French Italian Survival Norwegian Survival More...	Engineering Audio Engineering Computer Science Engineering Aerospace Engineering Chemical Engineering Structural Engineering More...
Health Sciences Basic Nursing Skills Health Science Language Fundamentals Veterinary Technology Medical Language Cardiology Clinical Surgery More...	English Grammar Fundamentals Literary And Rhetorical Vocab Elements Of Style Vocab Introduction To English Major Complete Advanced Sentences Literature Homonyms More...	Math Algebra Formulas Basic Arithmetic: Measurements Metric Conversions Geometric Properties Important Math Facts Number Sense Vocab Business Math More...	Other Major Subjects Science Economics History Law Performing-arts Cooking Logic & Reasoning Trivia

Test your basic knowledge |

USMLE Step 1 Prep

Sorry!:) No result found.

Can you answer 50 questions in 15 minutes?

Let me suggest you:

Browse all subjects

Browse all tests

Most popular tests

Major Subjects

Tests & Exams

Certifications

IT Skills

Business Skills

Soft Skills

Vocabulary

Languages

Engineering

Health Sciences

English

Math

Other Major Subjects

Browse all subjects

Browse all tests

Most popular tests