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USMLE Step 1 Prep

Subjects : health-sciences, usmle-step-1

Instructions:

Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can study here.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Where is the greatest venous PO2 in resting tissue?
CD40
C1 esterase inhibitor (C1INH)
Renal circulation
More than 75% of the vessel

2. What antiviral agent is used in the treatment of drug - induced Parkinson's disease?
Uracil
Amantadine
Hypoglycemia for secretion and hyperglycemia for inhibition
total body water

3. What Enterobacteriaceae are prone to produce osteomyelitis in sickle cell patients?
Kimmelstiel - Wilson disease
Histidine
Hepadnavirus
Salmonella

4. Which bacteria are associated with the following pigment production? - Yellow pigmentation
The surface of the medulla
Th2
Staphylococcus aureus
Tamoxifen

5. What three bacteria are positive to quellung reactive test?
Urogenital sinus
1. 7- methyl guanine cap on the 5' end 2. Addition of the poly(A) tail to the 3' end 3. Removal of introns
Poststreptococcal GN
1. Neisseria meningitidis 2. Haemophilus influenzae 3. Streptococcus pneumoniae

6. What type of bilirubin is found in neonatal jaundice?
Enterobius vermicularis; the treatment is albendazole.
Indirect or unconjugated
PPRF
ALA dehydrogenase and ferrochelatase

7. Regarding the viral growth curve - is the external virus present before or after the latent period?
C5b - C9
After the latent period
7 to 14 days
Flucytosine

8. What is the triad of fat embolism?
Stercobilin
Toxoplasmosis (although you should rule out cerebral abscess due to other organisms)
1. Petechiae 2. Hyperactive mental status 3. Occurrence within 24 to 48 hours of the initial insult (e.g. - long bone fracture)
Dystrophic calcification

9. When is the first arrested stage of development in the female reproductive cycle?
IL-5. It also stimulates eosinophil proliferation.
Prophase of meiosis I (between 12th and 22nd week in utero)
IgG
Arsenic - thorotrast - and vinyl chloride

10. Do the following structures pick up stain from hematoxylin or eosin? - Bacteria
Hematoxylin
In bone; nearly 99% of Ca2+ is stored in the bone as hydroxyapatite.
Voltage - gated channel
The Palmar interosseus ADducts - whereas the Dorsal interosseus ABducts (PAD and DAB)

11. What three CNs are associated with conjugate eye movements?
Skeletal muscles
Excretion is greater than filtration for net secretion to occur.
CN III - IV - and VI
Respiratory distress syndrome; treatment with cortisol and thyroxine can increase production of surfactant.

12. Name the valve abnormality based on the following criteria: x Diastolic murmur - increased right ventricular pressure - left atrial pressure - and atrial to ventricular pressure gradient; decreased left ventricular filling pressure
Mitral stenosis
Enkephalin
PGE 1 - PGI 2 (most potent) - and TXA 2
Middle meningeal artery

13. The nucleus is the site of...
Inferior pancreaticoduodenal - middle colic - right colic - ileocolic - and 10 to 15 intestinal arteries
Anticipation - associated with fragile X syndrome; Huntington's disease is also associated with a decrease in onset of age.
transcription
M12 strains

14. What blotting technique uses the following for analysis? - Protein
Substantia nigra
Western blot
Ampulla
Burkitt lymphoma

15. RBC casts in the urine
Exogenous steroids suppress LH release and result in Leydig cell atrophy. Testosterone - produced by Leydig cells - is needed for spermatogenesis.
Papillary carcinoma of the thyroid
Acute glomerulonephritis
Pseudomembranous colitis

16. What is the bioactive form of thyroid hormone?
Antimicrobial agents
T3
Parasites
Malpighian layer (made up of the stratum basale and stratum spinosum)

17. Which bacteria are associated with the following pigment production? - Pyocyanin (blue - green)
Pseudomonas aeruginosa
Secondary hypoparathyroidism (vitamin D toxicity)
Goodpasture disease
Nerve fibers with small diameter and high firing rates are most sensitive to local blockade

18. What artery is formed by the union of the two vertebral arteries?
Free ionized Ca2+
The basilar artery is formed at the pontomedullary junction.
Lingual nerve of CN V3
Bacillus anthracis

19. What are the adult remnants of the following structures? - Left umbilical vein
Theca cells secrete estrogen. After fertilization the theca cells form from the theca interna.
Reject it
Ligament teres
Pyridoxine (B6)

20. What antitubercular agent causes a red - orange tinge to tears and urine?
Rifampin
Primary hypoaldosteronism (Addison's disease)
Chromium (Cr)
Male pseudo - intersexuality (hermaphrodite); these individuals are 46XY.

21. What test is used to screen for HIV?
Chlamydia psittaci
CD15 and CD30
Cytosine
ELISA. It detects anti - p24 IgG.

22. What triggers phase 0 of the action potential in a ventricular pacemaker cell?
Vitamin A is responsible for vision and epithelial health.
Calcium influx secondary to slow channel opening
Arterioles
The greater the cell diameter - the greater the conduction velocity.

23. What water - soluble - vitamin deficiency is associated with neural tube defects in the fetus?
Series circuit
CD40
Folic acid
CN V2

24. What is the name of the B cell - rich area in the lymph node?
Variable ratio If it is based on time - it is an interval - and if it is based on the number of responses - it is a ratio.
Hirschsprung disease
Primary follicle of the cortex
Osteoblast (Remember - blasts make - clasts take)

25. Where are the postganglionic neuron cell bodies - the CNS or the PNS?
They are in ganglia in the PNS.
Adrenal medulla
Heroin
Adrenarche

26. What organism would you suspect in a patient with diarrhea after eating rice?
Labile
2 to 4 hours
REM latency; normally it is about 90 minutes.
Bacillus cereus

27. At what stage of cognitive development (according to Piaget) do children x See death as irreversible?
Immature B cells
Hirschsprung disease
Teeth grinding is associated with stage 2 sleep.
Concrete operations (6-12 years)

28. Where is renin produced?
DM - hypercholesterolemia - smoking - and HTN are major risk factors. Being male - obesity - sedentary lifestyle - homocysteine elevation - oral contraceptive pills - and genetics are minor risk factors for atherosclerosis.
2 days prior to ovulation
In the JG cells of the kidney
Poststreptococcal GN

29. What catecholamine - hypersecreting tumor - a secondary cause of HTN - results in headache - diaphoresis - anxiety - tachycardia - and palpitations?
Carnitine acyl CoA transferase II
Pheochromocytoma
Bronchogenic carcinoma
Inferior pancreaticoduodenal - middle colic - right colic - ileocolic - and 10 to 15 intestinal arteries

30. Name the type of necrosis - Histologically resembles fibrin
Fibrinoid necrosis
Free - unprocessed Ag
Inferior rectus (CN III) (LR6 SO4)3
Silicosis - Coal worker's pneumoconiosis is synonymous with black lung disease - an upper lobe occupational disorder

31. How many pairs of spinal nerves exit from the spinal cord?
Streptococci
Methanol
31 pairs
Femoral nerve

32. What endocrine abnormality is characterized by the following changes in PTH - Ca2+ - and inorganic phosphate (Pi)? - PTH increased - Ca2+ decreased - Pi decreased
Risperidone
Isocitrate dehydrogenase
Agglutination test
Secondary hyperparathyroidism (vitamin D deficiency - renal disease)

33. At what point does the axillary artery become the brachial artery?
When it crosses the teres major
Chromosome 5p
Serratia
Mean

34. Name the most common type or cause - UTIs
Escherichia coli
Sigmoid colon
Gangrenous necrosis
Esophagus and esophageal nerve plexus (CN X) Remember: 1 at T8 - 2 at T10 - and 3 at T12

35. Is digoxin or digitoxin renally eliminated?
Proencephalon
ACh
Dominant temporal lobe
Digoxin is renally eliminated; digitoxin is hepatically eliminated.

36. Name the MCC of death - In neonates
95% in the kidneys; that's why adequate Na+ and fluid intake is essential.
Beta- Galactosidase
Intellectualization
Neonatal respiratory distress syndrome (NRDS)

37. What form of dementia is characterized by onset at age 40 to 50 - rapid progression - infection by a prion - and death within 2 years?

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38. What type of test asks a patient to draw a scene - attempting to find out the individual's unconscious perceptions in his or her life?
Constipation and miosis
Being a white male
Projective drawing. The artistic form is irrelevant - but the size - placement - erasures - and distortions are relevant.
The placenta

39. What parasite is associated with squamous cell carcinoma of the urinary bladder?
Chromaffin cells (adrenal medulla)
Schistosoma haematobium
Cortisol - a 21- carbon steroid - has a - OH group at position 17.
Anhedonia

40. If one event precludes another event - their probabilities are combined By what method?
Nystagmus is named by the fast component - Which is the corrective attempt made by the cerebral cortex in response to the initial slow phase.
Addition (They are mutually exclusive.)
Mesangial macrophages
G-6- PD deficiency

41. What is the second leading cause of cancer deaths in males? In females?

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42. What are the two most important features in the diagnosis of malaria?
Water - soluble hormones are considered fast - acting hormones.
Splenomegaly and anemia (with a high index of suspicion)
Glucose -6- phosphatase
Invasive ductal carcinoma

43. What are the five AAs that are both ketogenic and glucogenic?
CN III and IV
Isoleucine - threonine - tryptophan - tyrosine - and phenylalanine
Yellow fever (flavivirus)
Conn syndrome (primary hyperaldosteronism)

44. Which organism releases endotoxins prior to cell death?
Selective erectile disorder
Neisseria meningitidis
The right gonadal vein drains into the inferior vena cava directly - and the left gonadal vein drains into the left renal vein.
Pick's disease

45. What three chemical agents are associated with angiosarcomas of the liver?
Arsenic - thorotrast - and vinyl chloride
Fc portion of IgG - C3b - and mannose - binding proteins
Escherichia coli
Broca's aphasia

46. With a decrease in arterial diastolic pressure - what happens to x Stroke volume?
Decreases
Ferritin
Systolic interval decreases secondary to increased contractility; diastolic interval decreases secondary to an increase in heart rate.
Venlafaxine. (It also has a mild dopaminergic effect.)

47. Name the compartment of the mediastinum associated with the following thoracic structures: IVC
Allopurinol
MHC class I antigens; they are also found on the surface of platelets.
Hematoxylin
Middle

48. What normochromic - normocytic AD anemia has splenomegaly and increased osmotic fragility?
Variola virus (Smallpox)
Hereditary spherocytosis
Pyridoxal phosphate is derived from vitamin B6 and is needed to transfer the amino groups of one carbon skeleton to another.
Heart disease

49. Which muscle of the eye is under sympathetic control?
Liver
Dilator pupillae muscle
Subarachnoid hematoma
Superoxide dismutase - glutathione peroxidase - catalase

50. What is the most common one? - Pancreatic islet cell tumor
Insulinoma
Glycogen synthase
Gardner syndrome
Krukenberg tumor