Test your basic knowledge |

Subject : health-sciences
Instructions:
  • Answer 50 questions in 15 minutes.
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  • Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. A group of more than 200 diseases characterized by the uncontrolled and unregulated growth of cells -caused by both external and internal factors -second leading cause of death in U.S.






2. Malignant transformation causing mutation of DNA Can be caused by: -Inherited mutation during DNA replication -Exposure to chemical - radiation - or virus (Carcinogens) -Cancer related genes






3. Starts in blood forming tissue such as bone marrow






4. Nausea & Vomiting -Bone marrow suppression -Alopecia: Hair loss -Weight gain or loss -Anorexia -Fatigue -Decline in functional status -Mucositis-'chemo' brain: foggyness that happens post chemo






5. Malignant transformation causing mutation of DNA Can be caused by: -Inherited mutation during DNA replication -Exposure to chemical - radiation - or virus (Carcinogens) -Cancer related genes






6. Appearance & degree of differentiation - Grading-> GX-G4






7. Most common cancer in American women -Second leading cause of cancer deaths in America -Bracogene defect






8. The use of cytotoxic drugs to destroy cancer cells -Multi-agent regimens superior to single drug administration -Can be used pre-op -Mainstay of therapy






9. Grade 1-4 - grade by cell when we can't tell where its from






10. Code for proteins to turn off cell growth - loss of function - Recessive






11. Limit Growth






12. Post surgery or chemotherapy - Goal to reduce risk of local recurrence






13. Surgery - Radiation - Chemotherapy - Biotherapy - Hormonal therapy






14. Different drugs to affect periods of cell cycle






15. 1.Breast 2.Prostate 3.Lung 4.Colon 5.UNK PRIM 6.Stomach 7.Rectum 8.pancreas 9.Bladder 10.Lymphoma 11.All other






16. Appearance & degree of differentiation - Grading-> GX-G4






17. Intravenous -Intraarterial -Intrapeitoneal -Intrathecal:into spinal canal -Intravesical Bladder -Oral






18. Based on spread of disease staging -Tumor Node Metastasis classification system -Stage 0-4






19. Primary Therapy -Neoadjuvant -Adjuvant (with something) -Prophylaxis -Disease Control -Palliation






20. Begin in the tissues of the brain and spinal cord






21. Burkitt's Lymphoma -Hodgkin's Lymphoma -Testicular cancer






22. 66%






23. Assist with decision making (teaching) -Assess psychosocial status & needs -Assess understanding of intervention -Reinforce info. about procedure - complications. - hospital procedures - & follow-up management -Educate regarding post-op self cares






24. Final stage -Increased growth rate of tumor -Increased invasiveness -Detectable mass= 1 cm and 1 billion cells






25. Given at the same time b/c different mechanisms of action that lower the amount of drugs given-> decrease toxicity






26. Depending upon site -skin: dry - itchy - red and irritated - desquamation (skin peeling) -Heart -Bowel & bladder -skin erythema -hyper pigmentation -Itching -Fatigue -Dry or moist desquamation -Edema -Loss of sensation -Pain






27. Spread of cancer from an initial site -Includes: angiogenesis - Invasion - Transport - Immunogenicity - arrest - Establishment of a secondary tumor






28. Starts in blood forming tissue such as bone marrow






29. Used in Prevention - determine the diagnostic and treatment plan (clinical staging) - Cure and or control of cancer - Supportive care - Rehabilitation - Palliation of symptoms - Diagnosis (biopsy)






30. Distinguishing the mutant cell (appearance & differentiation) aka histology






31. Education related to treatment & side effects -Ongoing skin assessment-Management of skin irritations -Assessment for fatigue- most common and disabling side effect -Education about fatigue management -rest periods-mild exercise -Emotional support du






32. Migration and proliferation of endothelial cells






33. Tobacco -1/3 of all new cases of cancer are related to nutrition - physical inactivity and obesity -Radiation (~1 billion new cases of basal and squamous cell skin cancer will be diagnosed this year)






34. -Defect in differentiation-Secrete enzyme to dissolve binding protein fibronectin- no cell surface adherence -Loss of ability to stop dividing- uncontrolled proliferation-Doubling time (exponential growth)-Loss of cell borders -ability to form new bl






35. Routine mammography-Digital mammography -Clinical breast examination -Breast self examination






36. Final stage -Increased growth rate of tumor -Increased invasiveness -Detectable mass= 1 cm and 1 billion cells






37. Cure - Control - palliation (pain relive)






38. Cells more abnormal - moderately differentiated






39. Breast cancer

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40. Strictly regulated -Predetermined to differentiate into specific cell type -Controlled cell death (apoptosis) & proliferation -Contact inhibition -Cell surface adherence-Inability to wander






41. Begin in the cells of the immune system






42. Exposure->mutation - Initiation - Promotion - Progression & metastasis






43. The ER and PR status of the tumor -The measures of proliferative capacity of the tumor -Her2/neu gene amplification.






44. Begins in the skin or in tissues that line or cover internal organs






45. Proteins and antigens - Monitor for recurrence






46. Assist with decision making (teaching) -Assess psychosocial status & needs -Assess understanding of intervention -Reinforce info. about procedure - complications. - hospital procedures - & follow-up management -Educate regarding post-op self cares






47. Intravenous -Intraarterial -Intrapeitoneal -Intrathecal:into spinal canal -Intravesical Bladder -Oral






48. Primary Therapy -Neoadjuvant -Adjuvant (with something) -Prophylaxis -Disease Control -Palliation






49. What cell is is? - How agressive?






50. Preoperative with or without chemotherapy - Goal to shrink tumor before surgery