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Subject : health-sciences
Instructions:
  • Answer 50 questions in 15 minutes.
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  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. The disease involves lymph nodes both above & below the diaphragm.






2. Cells are very abnormal - Moderately differentiated






3. 1.Breast 2.Prostate 3.Lung 4.Colon 5.UNK PRIM 6.Stomach 7.Rectum 8.pancreas 9.Bladder 10.Lymphoma 11.All other






4. Advanced age -Benign proliferate disease -Reproductive risk factors -Environmental (radiation & pestisides) -Hormonal factors (oral contraceptives)-Energy expenditure (weight gain - lack of physical activity)-Dietary risk factor: high fat intake & a






5. Exposure->mutation - Initiation - Promotion - Progression & metastasis






6. -Defect in differentiation-Secrete enzyme to dissolve binding protein fibronectin- no cell surface adherence -Loss of ability to stop dividing- uncontrolled proliferation-Doubling time (exponential growth)-Loss of cell borders -ability to form new bl






7. Surgery - Radiation - Chemotherapy - Biotherapy - Hormonal therapy






8. The age & menopausal status of patient -The stage of the disease






9. Strictly regulated -Predetermined to differentiate into specific cell type -Controlled cell death (apoptosis) & proliferation -Contact inhibition -Cell surface adherence-Inability to wander






10. Code for proteins to turn off cell growth - loss of function - Recessive






11. Starts in blood forming tissue such as bone marrow






12. Surgery - Radiation - Chemotherapy - Biotherapy - Hormonal therapy






13. Cells more abnormal - moderately differentiated






14. Final stage -Increased growth rate of tumor -Increased invasiveness -Detectable mass= 1 cm and 1 billion cells






15. Polypeptides that influence cell growth






16. Intravenous -Intraarterial -Intrapeitoneal -Intrathecal:into spinal canal -Intravesical Bladder -Oral






17. Starts in blood forming tissue such as bone marrow






18. Depending upon site -skin: dry - itchy - red and irritated - desquamation (skin peeling) -Heart -Bowel & bladder -skin erythema -hyper pigmentation -Itching -Fatigue -Dry or moist desquamation -Edema -Loss of sensation -Pain






19. Tumor cell to elicit and immune response






20. The lymphoma has advanced beyond the lymph nodes and spleen and has spread to one or more organs such as bone - bone marrow skin or liver.






21. The ER and PR status of the tumor -The measures of proliferative capacity of the tumor -Her2/neu gene amplification.






22. The ER and PR status of the tumor -The measures of proliferative capacity of the tumor -Her2/neu gene amplification.






23. 1st to occur because heart and brain are very important organs






24. Different drugs to affect periods of cell cycle






25. Inappropriately active versions of proto-oncogens (normal genes before mutation) code for proteins that induce malignant growth by turning on cell division (growth factors)






26. Based on spread of disease staging -Tumor Node Metastasis classification system -Stage 0-4






27. -Defect in differentiation-Secrete enzyme to dissolve binding protein fibronectin- no cell surface adherence -Loss of ability to stop dividing- uncontrolled proliferation-Doubling time (exponential growth)-Loss of cell borders -ability to form new bl






28. Used in Prevention - determine the diagnostic and treatment plan (clinical staging) - Cure and or control of cancer - Supportive care - Rehabilitation - Palliation of symptoms - Diagnosis (biopsy)






29. Mutation - Oncogenes - Tumor suppressor genes






30. Routine mammography-Digital mammography -Clinical breast examination -Breast self examination






31. Most common form - Linear accelerator generates ionizing radiation






32. Begin in the cells of the immune system






33. Begin in the cells of the immune system






34. Most common form - Linear accelerator generates ionizing radiation






35. Mutation - Oncogenes - Tumor suppressor genes






36. What cell is is? - How agressive?






37. The use of cytotoxic drugs to destroy cancer cells -Multi-agent regimens superior to single drug administration -Can be used pre-op -Mainstay of therapy






38. The cancer is found only in a single lymph node region or one organ or area outside the lymph node






39. Nausea & Vomiting -Bone marrow suppression -Alopecia: Hair loss -Weight gain or loss -Anorexia -Fatigue -Decline in functional status -Mucositis-'chemo' brain: foggyness that happens post chemo






40. Extent of disease






41. Migration and proliferation of endothelial cells






42. Given at the same time b/c different mechanisms of action that lower the amount of drugs given-> decrease toxicity






43. Secondary effect of an agent -alone may not be able to induce malignancy -some initiators may act as own promoters (cigarette tars) -activities of promoters is reversible






44. Breast cancer

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45. Migration and proliferation of endothelial cells






46. Cells are immature and primitive - Origin of cells difficult to determine






47. Given at the same time b/c different mechanisms of action that lower the amount of drugs given-> decrease toxicity






48. Blood - Lymph - Direct extension






49. Cure - Control - palliation (pain relive)






50. Most common cancer in American women -Second leading cause of cancer deaths in America -Bracogene defect







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