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Chemistry Certification
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Subject
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certifications
Instructions:
Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. The following five sodium control values (mEq/L) were obtained:140 - 135 - 138 - 140 - 142Calculate the coefficient of variation.
immunofixation
1.9
chylomicrons
porphobilinogen synthetase
2. This electrolyte is the chief plasma cation whose main function is maintaining osmotic pressure
fall in pH - rise in pCO2
decreased lecithin
thiamine
sodium
3. A 2-year-old child with a decreased serum T4 is described as being somewhat dwarfed - stocky - overweight - and having coarse features. Of the following - the most informative additional laboratory test would be the serum...
TSH
heparin
decreased lecithin
(testing of urine for) delta-am.. acid
4. Enzymes used in the diagnosis of acute pancreatitis?
270
testosterone
thyroxine binding globulin
amylase and lipase
5. Upon completion of a run of cholesterol tests - the technician recognizes that the controls are not within the two standard deviations confidence range. What is the appropriate course of action
MI
dirty electrodes
run a new set of controls
act as carriers for ions
6. Alkaline phosphatase Slight increase - Aminotransferase Marked increase - Aspartate aminotransferase Marked increase - Alanine gamma-glutamyl transferase Slight increase
Temperature is a function of the number of particles in solution
prevent phosphate interference
acute hepatitis
beta
7. A stool specimen that appears black and tarry should be tested for the presence of...
occult blood
CO2
creatinine clearance
potassium dichromate in SA
8. The formula for calculating serum osmolality that incorporates a correction for the water content of plasma is...
primidone
high co2 and hco3
2Na + glucose over 20 + BUN over 3
sharp fibrinogen peak
9. The selectivity of an ion-selective electrode is determined by the...
properties of the membrane
run a new set of controls
have a negative charge
Temperature is a function of the number of particles in solution
10. One international unit of enzyme activity is the amount of enzyme that - under specified reaction conditions of substrate concentration - pH - and temperature - causes utilization of substrate at the rate of...
one micromole/minute
20:1
analyzed immediately
check serum for hemolysis
11. The buffer pH most effective at allowing amphoteric proteins to migrate toward the cathode in an electrophoretic system would be...
lead
one micromole/minute
4.5
peroxidase-like activity of hemoglobin
12. The electrophoretic pattern of a plasma sample compared with a serum sample shows a...
show a decrease in glycosylated hgb
breast cancer
sharp fibrinogen peak
sodium potassium chloride CO2
13. Isoenzyme assays are preformed to improve...
specificity
remove excess unbound iron
measurement of absorbance at 450
scattered at a right angle
14. The main reason for suboptimal drug levels in therapeutic drug monitoring is...
(testing of urine for) delta-am.. acid
transferrin
g/MW
patient noncompliance
15. Amniotic fluid submitted for a lecithin/sphingomyelin (US) ratio has been left in a brown container since the night before. You would expect...
Hb S
carbs
BUN increased
decreased lecithin
16. Blood specimens for digoxin assays should be obtained between 8 hours or more after drug administration because...
bilirubin
freezing point
M subunit is inactivated
tissue and serum levels need to reach equilibrium
17. The urea nitrogen concentration of a serum sample was measured as 15 mg/dL (atomic weights: carbon = 12 - oxygen = 16 - nitrogen = 14 - hydrogen = 1). The urea concentration of the same sample - in mg/dL - is...
Wilson's disease
2Na + glucose over 20 + BUN over 3
32
diet
18. Gel filtration chromatography is used to separate...
volumetric flask
freezing point
one micromole/minute
cmpds based on molecular weight and size
19. A test request slip indicates that an acute porphyric attack is suspected clinically. Analysis should include...
obstructive jaundice
porphobilinigen SCREEN
CO2
porphyrin and porphobilinogen screen
20. Turbidity in serum suggests elevation of...
prevent phosphate interference
chylomicrons
albumin
HPLC analysis of porpobilinogen on 24hr urine
21. This condition does decrease activity of glucuronyl transferase result in increased unconjugated bilirubin and kernicterus in neonates
crigler
scattered at a right angle
Temperature is a function of the number of particles in solution
340
22. In the assay of lactate dehydrogenase - this product is actually measured
20:1
amytriptyline 104
can be separated into distinct phenotypes
NADH
23. The glucose level in normal peritoneal fluid should be...
200x affinity for oxygen
increased vasoconstriction
the same as plasma glucose
acute intermittent porphyria
24. This lipid results would be expected to be falsely elevated on a serum specimen from a nonfasting patient
be able to detect 9/10 simple instrument malfunctions
iron hemochromatosis
creatine kinase
trig
25. Serum anion gap is increased in patients with...
thyroxine binding globulin
lactic acidosis
<45
nondiagnostic for MS
26. A patient has the following results: Patient Values : Reference Values: Serum iron 250 ug/dL 60-150 ug/dL TIBC 350 ug/dL 300-35O ug/dL The best conclusion is that this patient has...
catalyze redox reactions
T4 by RIA
A1c
iron hemochromatosis
27. This hemoglobin has glucose-6-phosphate on the amino-terminal valine of the beta chain?
glycerol
120 minutes
A1c
whole blood can be used
28. The general types of interference in atomic absorption spectrophotometry...
1:5
chemical ionization matrix
5
20:1
29. A 25-year-old man became nauseated and vomited 90 minutes after receiving a standard 75-g carbohydrate dose for an oral glucose tolerance test. The best course of action is...
valine leucine isoleucine
draw blood for glucose and discontinue test
1.1
glucose
30. The formula for calculating the amount of moles of a chemical?
cmpds based on molecular weight and size
g/MW
1 micromole per minute
apoenzyme
31. As part of a hyperlipidemia screening program - the following results were obtained on a 25 year old woman 6 hours after eating:Triglycerides = 260 mg/dLCholesterol = 120 mg/dL - This is the BEST interpretation of these results?
cholesterol normal triglycerides elevated
@ 100
absorptivity x light path x concentration
impaired response to ACTH stimulation
32. Measurement of total T4 by competitive protein binding or displacement is based on the specific binding properties of...
thyroxine binding globulin
inclusion of smokers and nonsmokers in the study population
aldolase
breast cancer
33. This enzyme substrates for prostatic acid phosphatase determination results in the highest specificity
scattered at a right angle
can be separated into distinct phenotypes
thymolpthalein monophosphate
ALP with fresh draw
34. The function of the major lipid components of the very low density lipoproteins (VLDL) is to transport...
cancel test
tissue and serum levels need to reach equilibrium
para-hydroxylphenyl...
endogenous triglycerides
35. This steroid is an adrenal cortical hormone
corticosterone
there is an absence of correlation
LDL
Calcium - phosphorus
36. The chemical composition of HDL- cholesterol corresponds to...
breast cancer
5 tri 15 cholesterol 50 protein
exchange of amino and keto groups
Prolactin
37. An HPLC operator notes that the column pressure is too high - is rising too rapidly - and the recorder output is not producing normal peaks. The most probable cause of the problem is...
porphyrin and porphobilinogen screen
effluent line is obstructed
be able to detect 9/10 simple instrument malfunctions
intestinal malabsorption
38. Aminotransferase enzymes catalyze the...
100 nmol
incorrect aqueous to nonaqueous mixture
exchange of amino and keto groups
alpha 2 beta
39. The following laboratory results were obtained on arterial blood: Sodium 136 mEq/L pH 7.32 Potassium 4.4 mEq/L PCO2 79 mm Hg Chloride 92 mEq/L Bicarbonate 40 mEq/L These results are most compatible with...
thiamine
(testing of urine for) delta-am.. acid
prevent phosphate interference
respiratory acidosis
40. A 45-year-old woman has a fasting serum glucose concentration of 95 mg/dL and a 2-hour postprandial glucose concentration of 105 mg/dL. The statement that best describes this patient's fasting serum glucose concentration is...
200x affinity for oxygen
normal - liver breakdown
urinary free cortisol
standard
41. An increase in serum acetone is indicative of a defect in the metabolism of...
bicarbonate buffer
carbs
elevated lactic acid - elevated pyruvate
placenta
42. A common cause of respiratory alkalosis is...
hyperventilation
200
show a decrease in glycosylated hgb
A1
43. The most widely employed screening technique for drug abuse is...
incorrect aqueous to nonaqueous mixture
TLC
g/MW
urobilin
44. Lithium therapy is widely used in the treatment of...
manic-depression
nephelometry
340
5 tri 15 cholesterol 50 protein
45. A serum sample was assayed for bilirubin at 10 AM and the result was 12 mg/dL. The same sample was retested at 3 PM. The result now is 8 mg/dL. The most likely explanation for this discrepancy is...
run a new set of controls
sample exposed to light
amylase and lipase
dihydroxyacetone side chain
46. The protein portion of an enzyme complex is called the...
apoenzyme
5
340
chloride
47. When separating serum proteins by cellulose acetate electrophoresis using veronal buffer at pH 8.6 - beta globulin migrates...
oxalacetate to malate
cyclic antidepressants
<1%
faster than gamma
48. Creatinine clearance is used to estimate the...
GFR
albumin
CO2
turn off
49. In competitive inhibition of an enzyme reaction the...
32
Tay-sachs
measurement of absorbance at 450
inhibitor binds to enzyme at same site as substrate
50. A serum potassium is 19.5 mg/100 mL. This value is equal to how many mEq/L (MW of K = 39)?
properties of the membrane
minimize the effects of interference
measures one ion more than others
5
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