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Chemistry Certification

Instructions:

Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can study here.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Bromcresol purple at a pH of 5.2 is used in a colorimetric method to measure...
albumin
serum aliquots - one heated
ceruplasmin
elevated lactic acid - elevated pyruvate

2. Zinc protoporphyrin or free erythrocyte protoporphyrin measurements are useful to assess blood concentrations of...
catalyze redox reactions
creatinine
potassium dichromate in SA
lead

3. This serum constituent is unstable if a blood specimen is left standing at room temperature for 8 hours before processing
glucose oxidase
freezing point
glucose
increased O2 decreased HCO3

4. In competitive inhibition of an enzyme reaction the...
dirty electrodes
amylase
M subunit is inactivated
inhibitor binds to enzyme at same site as substrate

5. The general types of interference in atomic absorption spectrophotometry...
acute hepatitis
chemical ionization matrix
CO2 and pH elevated
Hb S

6. Blood received in the laboratory for blood gas analysis must meet these requirements
no ice clots bubbles
parathyroid
atomic absorption
whole blood can be used

7. Most drugs and intracellular metabolites measured by radioimmunoassay have molecular weights between 200 and 1000 and can be made immunogenic by...
volumetric flask
Temperature is a function of the number of particles in solution
one micromole/minute
attaching them to protein molecules

8. Major actions of angiotensin II include...
increased vasoconstriction
hepatobiliary (obstruction?)
turn off
apoenzyme

9. If the correlation coefficient (r) of two variables is zero...
2-log(T)
there is an absence of correlation
sample exposed to light
65

10. Blood samples were collected at the beginning of an exercise class and after 30 minutes of aerobic activity. This would be most consistent with the postexercise sample
1 micromole per minute
maintain colloidal osmotic pressure
creatinine clearance
elevated lactic acid - elevated pyruvate

11. In the sweat test - the sweating stimulant is introduced to the skin by application of...
ALP with fresh draw
parathyroid
Hb S
electric current

12. The most heat labile fraction of alkaline phosphatase is obtained from...
TLC
1 micromole per minute
multiplied by 4
bone

13. Given the following values:100;120;150;140;130;What is the mean?
2Na + glucose over 20 + BUN over 3
128
remove excess unbound iron
freezing point

14. A person suspected of having metabolic alkalosis would have these laboratory findings
iron deficiency anemia
prisms and grating
CO2 and pH elevated
C3 complement

15. In an internal standard flame photometer - the internal standard is used to...
4.5
correct for variations in flame and atomizer
primidone
accuracy

16. Gas chromatography with the nitrogen/phosphorus detector is the most commonly used technique for the analysis of...
cyclic antidepressants
no decrease in serum growth hormone after 90 minutes
monitoring the course of a known cancer
TSH

17. The selectivity of an ion-selective electrode is determined by the...
increase in total circulating T4
monitoring the course of a known cancer
properties of the membrane
mg/ml

18. Four children are admitted with malaise - anorexia - and abdominal pain. Further evaluations reveal mild anemia - erythrocyte basophilic stippling - and profound pica habits. Poisoning by which heavy metal is most likely responsible?
faster than gamma
mg/ml
lead
Tangier

19. When taken by a euthyroid individual - oral contraceptives containing estrogens will have this effects on the thyroid function studies
fetal and placenta function
increase in total circulating T4
purulent
minimize the effects of interference

20. The test for adrenal cortical hyperfunction that has the greatest diagnostic sensitivity is measurement of...
chloride
40-50
urinary free cortisol
Temperature is a function of the number of particles in solution

21. A blood sample was received from the emergency room with a request for narcotic analysis. The request slip indicated that the patient (a known heroin addict) responded to naloxone administration. The serum was negative for morphine by EIA. What other
fresh morning urine for delta-aminolevulinic acid
diet
lead
methadone

22. Detection of carriers of hereditary coproporphyria should include analysis of...
corticosterone
fresh morning urine for delta-aminolevulinic acid
lithium
@ 100

23. At blood pH 7.40 what is the ratio between bicarbonate and carbonic acid?
increased vasoconstriction
20:1
B12 deficiency
100 nmol

24. When myocardial infarction occurs - the first enzyme to become elevated is...
parathyroid hormone
CK-MB
CK
whole blood can be used

25. In electrophoresis of serum proteins - arifacts at the application point are most frequently caused by...
acute hepatitis
dirty applicators
nondiagnostic for MS
increased O2 decreased HCO3

26. About 90% of phenytoin is excreted in the urine as...
trig
T4 by RIA
atomic absorption
para-hydroxylphenyl...

27. A blood gas sample was sent to the lab on ice - and a bubble was present in the syringe. The blood had been exposed to room air for at least 30 minutes. The following change in blood gases occurred...
no decrease in serum growth hormone after 90 minutes
Mg
pO2 increased HCO3 decreased
TSH

28. The T3 resin uptake test is a measure of...
fraction absorbed into systemic circulation
binding capacity of thyroxine-binding globulin
standard
thyroxine

29. Nephelometers measure light...
0
scattered at a right angle
@ 100
Temperature is a function of the number of particles in solution

30. The TRH (thyrotropin-releasing hormone) stimulation test is useful in assessing...
nephelometry
glucose tolerance test
hyperthyroidism
creatinine

31. In developing the reference for a new EIA for CEA - the range for the normal population was broader than that published by the vendor. Controls are acceptable with a narrow coefficient of variation. This may be explained by...
inclusion of smokers and nonsmokers in the study population
2Na + glucose over 20 + BUN over 3
HPLC analysis of porpobilinogen on 24hr urine
Solute moves half the distance of the solvent front

32. Currently the most common method for specific identification and quantitation of serum barbiturates is...
ammonia
growth - third trimester of pregnancy
porphobilinogen screen
GLC

33. The serum glucose concentration of a diabetic patient undergoing a 2-hour glucose tolerance test should return to the baseline (fasting level) after a minimum of...
whole blood can be used
120 minutes
ALP with fresh draw
monitoring the course of a known cancer

34. A sweat chloride result of 55 mEq/L and a sweat sodium of 52 mEq/L were obtained ona patient who has a history of respiratory problems. The bestc interpretation of these results is...
biuret
crigler
boderline results test should be repeated
endogenous triglycerides

35. The enzyme present in almost all tissues that may be separated by electrophoresis into five components is...
there is an absence of correlation
amylase and lipase
LDH
CML

36. A 25-year-old man became nauseated and vomited 90 minutes after receiving a standard 75-g carbohydrate dose for an oral glucose tolerance test. The best course of action is...
accuracy
is quantitated by the amount of light produced
draw blood for glucose and discontinue test
CO2 and pH elevated

37. The following data were obtained from a cellulose acetate protein electrophoresis scan: Albumin area 75 units Gamma globulin area 30 units Total area 180 units Total protein 6.5 g/dL The gamma globulin content in g/dL is...
carbohydrate hyperalimentation
dirty electrodes
1.1
fraction absorbed into systemic circulation

38. Stray light can be detected in a spectrophotometer by utilizing a...
testing heparinized plasma
valine leucine isoleucine
591
sharp cutoff filter

39. One international unit of enzyme activity is the amount of enzyme that - under specified reaction conditions of substrate concentration - pH - and temperature - causes utilization of substrate at the rate of...
accuracy
ceruplasmin
atomic absorption
1 micromole per minute

40. This would be an example of a glucose-specific colorimetric method
freezing point
1 micromole per minute
glucose oxidase
prostate

41. The anion gap is useful for quality control of laboratory results for...
(testing of urine for) delta-am.. acid
sodium potassium chloride CO2
acute hepatitis
enzyme immunoassay

42. An automated method for measuring chloride that generates silver ions in the reaction is...
quantitation of label
carbs
coulometry
C

43. Serum levels that define hypoglycemia in preterm or low birth weight infants are...
pCO2
lower than in adults
glycerol
effluent line is obstructed

44. A spectrophotometer is being considered for purchase by a small laboratory. This specification reflects the spectral purity of the instrument
ALP with fresh draw
testing heparinized plasma
band width
TSH

45. Acidosis and alkalosis are best defined as fluctuations in blood pH and CO2 content due to changes in...
32
bicarbonate buffer
urobilin
inhibitor binds to enzyme at same site as substrate

46. The definitive diagnosis of primary adrenal insufficiency requires demonstration of...
impaired response to ACTH stimulation
BUN increased
maintain colloidal osmotic pressure
TSH

47. The anticonvulsant used to control tonic-clonic (grand mal) seizures is...
iron hemochromatosis
phenytoin
fetal and placenta function
whole blood can be used

48. Fluctuation of the needle on a coulometric type titrator is most probably due to...
iron hemochromatosis
dirty electrodes
hyperthyroidism
200

49. The biologically most active - naturally occuring androgen is...
1:5
testosterone
Mg
check serum for hemolysis

50. A condition in which erythrocyte protoporphyrin is increased is...
C3 complement
pCO2
iron deficiency anemia
amytriptyline 104