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Chemistry Certification
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Subject
:
certifications
Instructions:
Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. In the fasting state - the arterial and capillary blood glucose concentration varies from the venous glucose concentration by approximately how many mg/dL?
beta
manic-depression
5mg higher
measures one ion more than others
2. The osmolality of a urine or serum specimen is measured by a change in the...
digoxin
enzyme induction
freezing point
thyroxine
3. This method offers the greatest sensitivity for HBsAg testing
enzyme immunoassay
hemolysis
ionic charge
creatinine
4. One international unit of enzyme activity is the amount of enzyme that - under specified reaction conditions of substrate concentration - pH - and temperature - causes utilization of substrate at the rate of...
1 micromole per minute
cyclic antidepressants
hyperventilation
amylase
5. A fasting serum sample from an asymptomatic 43-year-old woman is examined visually chemically with the following results: Initial appearance of serum: Milky Appearance of serum after overnight refrigeration: Cream layer over turbid serum Triglyceri
M subunit is inactivated
Wilson's disease
low pH
chylomicrons VLDL
6. In amniotic fluid - the procedure used to detect Rh isosensitization is...
BUN 80
remove excess unbound iron
measurement of absorbance at 450
adding an acid stabilizer
7. The reason carbon monoxide is so toxic is because it...
200x affinity for oxygen
hepatobiliary (obstruction?)
cyclic antidepressants
act as carriers for ions
8. A blood creatinine value of 5.0 mg/dL is most likely to be found with this blood value?
CML
wavelength
elevated lactic acid - elevated pyruvate
BUN 80
9. Hydrogen ion concentration (pH) in blood is usually determined by means of these electrodes?
glass
<45
porphobilinigen SCREEN
prevent phosphate interference
10. A fresh urine sample is received for "porphyrins" or "porphyria" without further information or specifications. Initial analysis should include...
Prolactin
porphyrin and porphobilinogen screen
freezing point
inclusion of smokers and nonsmokers in the study population
11. Magnesium carbonate is added in an iron binding capacity determination in order to...
remove excess unbound iron
270
can be used for absorbtion - partition - ion exchange - and gel permeation chromatography
dirty electrodes
12. The different water content of erythrocytes and plasma makes true glucose concentrations in whole blood a function of the...
oxalacetate to malate
HCT
there is an absence of correlation
band width
13. While performing a serum lithium determination on a flame photometer with cesium as the internal standard - the technologist noticed that there was a flickering flame. The most probable cause of this problem is...
glucose oxidase
changes in the fuel
chloride
BUN increased
14. A patient is admitted to the emergency room in a state of metabolic alkalosis.This would be consistent with this diagnosis?
monitoring the course of a known cancer
exposure to CO
high co2 and hco3
Calcium - phosphorus
15. Unless blood gas measurements are made immediately after sampling - in vitro glycolysis of the blood causes a...
fall in pH - rise in pCO2
decreased lecithin
pH pCO2 pO2
1 mol/kg
16. Turbidity in serum suggests elevation of...
crigler
chylomicrons
LDL
0
17. An automated method for measuring chloride that generates silver ions in the reaction is...
200x affinity for oxygen
340
coulometry
acute hepatitis
18. The test for adrenal cortical hyperfunction that has the greatest diagnostic sensitivity is measurement of...
porphobilinogen screen
fetal and placenta function
WITHOUT a disease with a negative test
urinary free cortisol
19. In a normal individual - injection of thyrotropin-releasing hormone (TRH) causes an increase in blood concentrations of this hormone
TSH
emphysema
Prolactin
1:5
20. This electrolyte is the chief plasma cation whose main function is maintaining osmotic pressure
atomic absorption
sodium
acute intermittent porphyria
mg/ml
21. A potentiometric electrode that measures an analyte that passes through a selectively premeable membrane and rapidly enters into an equilibrium with an electrolyte solution is...
no decrease in serum growth hormone after 90 minutes
biuret
ionic charge
pCO2
22. Serum and urine copper levels are assayed on a hospital patient with the following results: Patient Serum Cu: 58 ug/dL; Reference Value:70-140 ug/dL Patient Urine Cu: 83 ug/dL ; Reference Value: < 40 ug/dL This is most consistent with...
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23. The most widely used support medium for electrophoretic separation of lipoproteins is...
conjugated hyperbilirubinemia - hepatocellular obstruction
hyperthyroidism
immunofixation
agarose
24. About 90% of phenytoin is excreted in the urine as...
multiplied by 4
carbohydrate hyperalimentation
para-hydroxylphenyl...
<1%
25. The first step in analyzing a 24-hour urine specimen for quantitative urine protein is...
serum cortisol > 15
measure the total volume
atomic absorption
GLC
26. Upon development of a thin layer chromatogram for the drug analysis - all drug spots (including the standards) had migrated with the solvent front. The most probable cause for this would be...
incorrect aqueous to nonaqueous mixture
changes in the fuel
glucose
nondiagnostic for MS
27. This lipid results would be expected to be falsely elevated on a serum specimen from a nonfasting patient
diet
one micromole/minute
M subunit is inactivated
trig
28. This enzyme substrates for prostatic acid phosphatase determination results in the highest specificity
incorrect aqueous to nonaqueous mixture
heparin
128
thymolpthalein monophosphate
29. Following overnight fasting - hypoglycemia in adults is defined as a glucose of...
thiamine
MI
atomic absorption
<45
30. Nephelometers measure light...
primidone
parathyroid hormone
scattered at a right angle
TSH
31. The fast hemoglobin fraction is...
Hb S
serum aliquots - one heated
A1
cancel test
32. A condition in which erythrocyte protoporphyrin is increased is...
iron deficiency anemia
mg/ml
biuret
creatinine clearance
33. A technician is asked by the supervisor to prepare a standard solution from the stock standard. What is the glassware of choice for this solution?
inhibitor binds to enzyme at same site as substrate
exchange of amino and keto groups
volumetric flask
corticosterone
34. The following bilirubin results are obtained on a patient: Day 1: 4.3 mg/dL Day 4: 2.2 mg/dL Day 2: 4.6 mg/dL Day 5: 4.4 mg/dL Day 3: 4.5 mg/dL Day 6: 4.5 mg/dL - Given that the controls were within range each day - what is a probable explanation for
specimen exposure to light
correct for variations in light intensity
the same as plasma glucose
beta
35. This is a characteristic shared by lactate dehydrogenase - malate dehydrogenase - isocitrate dehydrogenase - and hydroxybutyrate dehydrogenase?
CML
glucose tolerance test
acid phosphatase
catalyze redox reactions
36. Spectrophotometers isolate a narrow band pass by means of...
iron deficiency anemia
prisms and grating
T4 by RIA
bilirubindiglucuronide
37. The relative migration rate of proteins on cellulose acetate is based on...
ionic charge
immunofixation
100nmol
decreased lecithin
38. Most drugs and intracellular metabolites measured by radioimmunoassay have molecular weights between 200 and 1000 and can be made immunogenic by...
attaching them to protein molecules
g/MW
didymium filter
pH = pKa + log (salt/acid)
39. How many grams of sodium chloride are needed to prepare 1 L of 0.9% normal saline?
accuracy
carbs
T4 by RIA
9
40. Kernicterus is an abnormal accumulation of bilirubin in...
21-hydroxylase deficiency
brain
@ 100
viral hepatitis
41. An electrode has a silver/silver chloride anode and a platinum wire cathode. It is suspended in KCl solution and separated from the blood to be analyzed by a selectively permeable membrane. Such an electrode is used to measure...
O2
3500
90%
growth - third trimester of pregnancy
42. 4 mL of water is added to 1 mL of serum. This represents this serum dilutions
cysteine
(testing of urine for) delta-am.. acid
increased vasoconstriction
1:5
43. Sixty to seventy-five percent of the plasma cholesterol is transported by...
brain
chylomicrons VLDL
LDL
TSH
44. Upon completion of a run of cholesterol tests - the technician recognizes that the controls are not within the two standard deviations confidence range. What is the appropriate course of action
D
run a new set of controls
1 mol/kg
dihydroxyacetone side chain
45. Serum from a patient with metastatic carcinoma of the prostate was separated from the clot and stored at room temperature. The following results were obtained: Patient Reference Range Calcium: 10.8 mg/dL 8.8-10.3 mg/dL LD:420 U/L 50-150 U/L Acid phos
creatinine clearance
chloride
pH = pKa + log (salt/acid)
ALP with fresh draw
46. The anticonvulsant used to control tonic-clonic (grand mal) seizures is...
sodium potassium chloride CO2
phenytoin
elevated lactic acid - elevated pyruvate
HCT
47. In the immunoinhibition phase of the CK-MB procedure...
whole blood can be used
M subunit is inactivated
32
primary hyperparathyroidism
48. The unit of measure for a standard solution is...
bicarbonate carbonic acid
1:5
mg/ml
agarose
49. The presence of this isoenzymes indicates acute myocardial damage
CK-MB
a small concentration of APO-B containing lipoproteins after precipitation
breast cancer
NADH
50. Most automated blood gas analyzers directly measure...
attaching them to protein molecules
pO2 increased HCO3 decreased
bicarbonate buffer
pH pCO2 pO2
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