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Test your basic knowledge |
Chemistry Certification
Start Test
Study First
Subject
:
certifications
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. The formula for calculating the amount of moles of a chemical?
GGT
Tangier
g/MW
measures one ion more than others
2. A patient in her 33rd week of pregnancy is hospitalized with toxemia. Her doctor would like to deliver the baby early because the toxemia is becoming more severe. The baby's best chance of delivery without respiratory distress due to lung immaturity
be able to detect 9/10 simple instrument malfunctions
32
L/S ratio > 3.5
iron deficiency anemia
3. This hemoglobin has glucose-6-phosphate on the amino-terminal valine of the beta chain?
A1c
glycerol
2-log(T)
monitoring the course of a known cancer
4. Fluctuation of the needle on a coulometric type titrator is most probably due to...
dirty electrodes
conjugated hyperbilirubinemia - hepatocellular obstruction
bicarbonate buffer
minimize the effects of interference
5. After a difficult venipuncture requiring prolonged application of the tourniquet - the serum K+ was found to be 6.8 mEq/L. The best course of action is to...
270
chylomicrons VLDL
specificity
cancel test
6. The principle of the occult blood test depends on the...
peroxidase-like activity of hemoglobin
CK-MB
WITHOUT a disease with a negative test
growth - third trimester of pregnancy
7. A blood gas sample was sent to the lab on ice - and a bubble was present in the syringe. The blood had been exposed to room air for at least 30 minutes. The following change in blood gases occurred...
2-log(T)
200x affinity for oxygen
acute intermittent porphyria
increased O2 decreased HCO3
8. A true statement about high performance liquid chromatography (HPLC) is that it...
can be used for absorbtion - partition - ion exchange - and gel permeation chromatography
enzyme induction
100nmol
decreased lecithin
9. The biologically most active - naturally occuring androgen is...
acid phosphatase
transferrin
testosterone
GGT
10. The main reason for suboptimal drug levels in therapeutic drug monitoring is...
testosterone
peptide bonds
patient noncompliance
@ 100
11. A psychiatric patient was experiencing sever depression - but responded to treatment with amitriptyline with no apparent side effects. A blood sample was sent to the laboratory for therapeutic monitoring. Which drug level would be MOST reflective of
cyclic antidepressants
amytriptyline 104
bilirubin
check serum for hemolysis
12. High levels of which lipoprotein class are associated with decreased risk of accelerated atherosclerosis?
HDL
ionization of carboxyl groups (yielding a net negative charge)
ALP with fresh draw
fetal and placenta function
13. What specimen preparation is commonly used to perform the alkaline phosphatase isoenzyme determination?
serum aliquots - one heated
GFR
dirty electrodes
phenytoin
14. The relative migration rate of proteins on cellulose acetate is based on...
peptide bonds
heparin
have a negative charge
ionic charge
15. The methodology based on the amount of energy absorbed by a subtance as a function of its concentration and using a specific source of the same material as the substance analyzed is...
g/MW
atomic absorption
normal - liver breakdown
draw blood for glucose and discontinue test
16. This enzymes catalyzes the conversion of starch to glucose and maltose
<1%
amylase
endogenous triglycerides
wavelength
17. About 90% of phenytoin is excreted in the urine as...
occult blood
340
para-hydroxylphenyl...
lipase
18. The following bilirubin results are obtained on a patient: Day 1: 4.3 mg/dL Day 4: 2.2 mg/dL Day 2: 4.6 mg/dL Day 5: 4.4 mg/dL Day 3: 4.5 mg/dL Day 6: 4.5 mg/dL - Given that the controls were within range each day - what is a probable explanation for
specimen exposure to light
TLC
creatinine clearance
glucose tolerance test
19. Upon development of a thin layer chromatogram for the drug analysis - all drug spots (including the standards) had migrated with the solvent front. The most probable cause for this would be...
591
incorrect aqueous to nonaqueous mixture
catalyze redox reactions
electric current
20. A condition in which erythrocyte protoporphyrin is increased is...
32
purulent
1 micromole per minute
iron deficiency anemia
21. The following results were obtained in a creatinine clearance evaluation: Urine concentration 84 mg/dL Urine volume 1440 mL/24 hr Serum concentration 1.4 mg/dL Body surface area 1.60 m2 (average = 1.73 m2) The creatinine cle~trance in mL/min is...
chloride
GLC
65
thiamine
22. A patient with hemolytic anemia will...
the fetus is at risk for respiratory distress
4.5
show a decrease in glycosylated hgb
effluent line is obstructed
23. The definitive diagnosis of primary adrenal insufficiency requires demonstration of...
MI
impaired response to ACTH stimulation
albumin
elevated lactic acid - elevated pyruvate
24. The osmolal gap is defined as measured Osm/kg minus the calculated Osm/kg. The average osmolal gap is near...
HDL
amylase and lipase
creatinine clearance
0
25. The expected blood gas results for a patient in chronic renal failure would match the pattern of...
Solute moves half the distance of the solvent front
metabolic acidosis
ceruplasmin
plasma bicarbonate
26. Rickets is associated with deficiency of...
D
high carbohydrate diet for 3 days
occult blood
aldolase
27. A fresh urine sample is received for "porphyrins" or "porphyria" without further information or specifications. Initial analysis should include...
porphyrin and porphobilinogen screen
draw blood for glucose and discontinue test
can be used for absorbtion - partition - ion exchange - and gel permeation chromatography
sodium potassium chloride CO2
28. A patient with type I insulin-dependent diabetes mellitus has the following results: Fasting blood glucose: 150 mg/dL (70-110 rng/dL) Hemoglobin A1c: 25% (6.0%-19.5%) Fructosamine: 3.0 mmol/L ( 2.0-5.3 mmol/L)
hepatobiliary (obstruction?)
improving state of metabolic control (as indicated by fructosamine)
enzyme induction
enzyme immunoassay
29. Regan isoenzyme has the same properties as alkaline phosphatase that originates in the...
run a new set of controls
can be used for absorbtion - partition - ion exchange - and gel permeation chromatography
1.9
placenta
30. Pregnant women with symptoms of thirst - frequent urination - or unexplained weight loss should have this test performed?
measurement of absorbance at 450
glucose tolerance test
prevent phosphate interference
GGT
31. The method of choice for diagnosis of a protracted attack of porphyria is...
whole blood can be used
CO2
WITHOUT a disease with a negative test
HPLC analysis of porpobilinogen on 24hr urine
32. When taken by a euthyroid individual - oral contraceptives containing estrogens will have this effects on the thyroid function studies
pH = pKa + log (salt/acid)
Temperature is a function of the number of particles in solution
amylase and lipase
increase in total circulating T4
33. The presence of this isoenzymes indicates acute myocardial damage
CK-MB
90%
T4 by RIA
HPLC analysis of porpobilinogen on 24hr urine
34. When separating serum proteins by cellulose acetate electrophoresis using veronal buffer at pH 8.6 - beta globulin migrates...
serum aliquots - one heated
faster than gamma
sodium potassium chloride CO2
chylomicrons VLDL
35. A 9-month-old boy from Israel has gradually lost the ability to sit up and develops seizures. He has an increased amount of a phospholipid called GM2-ganglioside in his neurons - and he lacks the enzyme hexosaminidase A in his leukocytes. These findi
urobilin
porphobilinigen SCREEN
Tay-sachs
one micromole/minute
36. The most sensitive enzymatic indicator for liver damage from ethanol intake is...
GGT
measures one ion more than others
Prolactin
TLC
37. The osmolality of a urine or serum specimen is measured by a change in the...
freezing point
analyzed immediately
growth - third trimester of pregnancy
oxalacetate to malate
38. Analysis of erythrocytes for uroporphyrinogen I synthetase detects...
transferrin
hyperventilation
ammonia
acute intermittent porphyria
39. A patient is admitted to the emergency room in a state of metabolic alkalosis.This would be consistent with this diagnosis?
high co2 and hco3
whole blood can be used
A1
bone
40. The normal concentration of proteins in cerebrospinal fluid - relative to serum protein - is...
CO2
ALP with fresh draw
<1%
carbohydrate hyperalimentation
41. A critically ill patient becomes comatose. The physician believes the coma is due to hepatic failure. The assay most helpful in this diagnosis is...
(testing of urine for) delta-am.. acid
HCT
ammonia
a small concentration of APO-B containing lipoproteins after precipitation
42. This 2-hour postprandial glucose values demonstrates unequivocal hyperglycemia diagnostic for diabetes mellitus
one micromole/minute
Tay-sachs
200
prisms and grating
43. Bromcresol purple at a pH of 5.2 is used in a colorimetric method to measure...
1.9
CK-MB
albumin
100 nmol
44. The following five sodium control values (mEq/L) were obtained:140 - 135 - 138 - 140 - 142Calculate the coefficient of variation.
1.9
4.5
<45
Temperature is a function of the number of particles in solution
45. A one MOLAL solution is equivalent to...
BUN increased
1 mol/kg
C
creatine kinase
46. The direction in which albumin migrates (ie - toward anode or cathode) during electrophoretic separation of serum proteins - at pH 8.6 - is determined by...
properties of the membrane
prevent phosphate interference
lactic acidosis
ionization of carboxyl groups (yielding a net negative charge)
47. The serum glucose concentration of a diabetic patient undergoing a 2-hour glucose tolerance test should return to the baseline (fasting level) after a minimum of...
120 minutes
freezing point
2Na + glucose over 20 + BUN over 3
pO2 increased HCO3 decreased
48. Detection of carriers of hereditary coproporphyria should include analysis of...
low pH
urinary free cortisol
fresh morning urine for delta-aminolevulinic acid
minimize the effects of interference
49. Maple syrup urine disease is characterized by an increase in this urinary amino acids
purulent
there is an absence of correlation
valine leucine isoleucine
Solute moves half the distance of the solvent front
50. As part of a hyperlipidemia screening program - the following results were obtained on a 25 year old woman 6 hours after eating:Triglycerides = 260 mg/dLCholesterol = 120 mg/dL - This is the BEST interpretation of these results?
cholesterol normal triglycerides elevated
fresh morning urine for delta-aminolevulinic acid
trig
measure the total volume