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Test your basic knowledge |
Chemistry Certification
Start Test
Study First
Subject
:
certifications
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Ion selective electrodes are called selective rather than specific because they actually measure the...
measures one ion more than others
aldolase
acute intermittent porphyria
methyl alcohol
2. In thin layer chromatography - the Rf value for a compound is given by the...
increase in total circulating T4
endogenous triglycerides
amytriptyline 104
ratio of distance moved by solvent to distance moved by compound
3. Given the following values:100;120;150;140;130;What is the mean?
128
there is an absence of correlation
serum cortisol > 15
cysteine
4. The unit of measure for a standard solution is...
mg/ml
cholesterol normal triglycerides elevated
ammonia
phenytoin
5. Cerebrospinal fluid for glucose assay should be...
glass
analyzed immediately
prostate
impaired response to ACTH stimulation
6. This applies to cryoscopic osmometry
Temperature is a function of the number of particles in solution
MI
trig
GFR
7. This would be an example of a glucose-specific colorimetric method
corticosterone
glucose oxidase
sample exposed to light
respiratory ACIDOSIS
8. A critically ill patient becomes comatose. The physician believes the coma is due to hepatic failure. The assay most helpful in this diagnosis is...
ammonia
elevated lactic acid - elevated pyruvate
apoenzyme
CML
9. Diagnostic specificity is defined as the percentage of individuals...
without a disease with a negative test result
(testing of urine for) delta-am.. acid
nephelometry
90%
10. The direction in which albumin migrates (ie - toward anode or cathode) during electrophoretic separation of serum proteins - at pH 8.6 - is determined by...
ionization of carboxyl groups (yielding a net negative charge)
1.9
faster than gamma
SD over mean
11. The main reason for suboptimal drug levels in therapeutic drug monitoring is...
run a new set of controls
90%
2-log(T)
patient noncompliance
12. This 2-hour postprandial glucose values demonstrates unequivocal hyperglycemia diagnostic for diabetes mellitus
viral hepatitis
specificity
scattered at a right angle
200
13. Upon development of a thin layer chromatogram for the drug analysis - all drug spots (including the standards) had migrated with the solvent front. The most probable cause for this would be...
L/S ratio > 3.5
serum cortisol > 15
aldolase
incorrect aqueous to nonaqueous mixture
14. The formula for calculating absorbance given the percent transmittance (%T) of a solution
2-log(T)
catalyze redox reactions
prisms and grating
without a disease with a negative test result
15. Thiis serum protein fraction is most likely to be elevated in patients with nephrotic syndrome?
5
porphobilinogen synthetase
<1%
alpha 2 beta
16. Calcium concentration in the serum is regulated by...
120 minutes
acid phosphatase
peroxidase-like activity of hemoglobin
parathyroid hormone
17. The most specific enzyme test for acute pancreatitis is...
CML
CO2 and pH elevated
lipase
CK-MB
18. The most consistent analytical error involved in the routine determination of HDLcholesterol is caused by...
intestinal malabsorption
T4 by RIA
a small concentration of APO-B containing lipoproteins after precipitation
acid phosphatase
19. This is a glycolytic enzyme that catalyzes the cleavage of fructose-1 - 6-diphosphate to glyceraldehyde-3-phosphate and dihydroxyacetone phosphate
5
aldolase
acute intermittent porphyria
sharp fibrinogen peak
20. Blood received in the laboratory for blood gas analysis must meet these requirements
conjugated hyperbilirubinemia - hepatocellular obstruction
no ice clots bubbles
obstructive jaundice
1.1
21. An Rf value of 0.5 in thin-layer chromatography means...
methyl alcohol
emphysema
bilirubin
Solute moves half the distance of the solvent front
22. One means of checking a spectrophotometer wavelength calibration in the visible range is by using a...
high carbohydrate diet for 3 days
changes in the fuel
didymium filter
CO2
23. The following results were obtained in a creatinine clearance evaluation: Urine concentration 84 mg/dL Urine volume 1440 mL/24 hr Serum concentration 1.4 mg/dL Body surface area 1.60 m2 (average = 1.73 m2) The creatinine cle~trance in mL/min is...
65
tissue and serum levels need to reach equilibrium
valine leucine isoleucine
chylomicrons
24. This serum constituent is unstable if a blood specimen is left standing at room temperature for 8 hours before processing
cmpds based on molecular weight and size
run a new set of controls
correct for variations in light intensity
glucose
25. The concentration of serum carotene is affected MOST by...
placenta
show a decrease in glycosylated hgb
diet
specificity
26. Certain enzymes are activated to metabolize drugs as a result of another drug action. This is referred to as...
enzyme induction
boderline results test should be repeated
thyroxine
LDL
27. The formula for calculating serum osmolality that incorporates a correction for the water content of plasma is...
g/MW
sharp cutoff filter
exposure to CO
2Na + glucose over 20 + BUN over 3
28. The protein portion of an enzyme complex is called the...
591
apoenzyme
thiamine
B12 deficiency
29. Assay of transketolase activity in blood is used to detect deficiency of...
591
thiamine
acute hepatitis
pO2 increased HCO3 decreased
30. A serum sample for acid phosphatase determination is best prepared for room temperature storage by...
cysteine
adding an acid stabilizer
thiamine
porphobilinogen screen
31. In electrophoretic analysis - buffers...
lithium
act as carriers for ions
freezing point
respiratory acidosis
32. Regan isoenzyme has the same properties as alkaline phosphatase that originates in the...
placenta
endosmosis
properties of the membrane
chloride
33. Bioavailability of a drug refers to the...
fraction absorbed into systemic circulation
placenta
4.5
parathyroid
34. Four children are admitted with malaise - anorexia - and abdominal pain. Further evaluations reveal mild anemia - erythrocyte basophilic stippling - and profound pica habits. Poisoning by which heavy metal is most likely responsible?
growth - third trimester of pregnancy
Calcium - phosphorus
digoxin
lead
35. The principle of the occult blood test depends on the...
peroxidase-like activity of hemoglobin
BUN increased
sharp fibrinogen peak
nephelometry
36. Sixty to seventy-five percent of the plasma cholesterol is transported by...
L/S ratio > 3.5
LDL
digoxin
primidone
37. In electrophoresis of serum proteins - arifacts at the application point are most frequently caused by...
TSH
adding an acid stabilizer
ionization of carboxyl groups (yielding a net negative charge)
dirty applicators
38. Following overnight fasting - hypoglycemia in adults is defined as a glucose of...
parathyroid hormone
enzyme induction
ratio of distance moved by solvent to distance moved by compound
<45
39. After a difficult venipuncture requiring prolonged application of the tourniquet - the serum K+ was found to be 6.8 mEq/L. The best course of action is to...
cancel test
specimen exposure to light
plasma bicarbonate
primary hyperparathyroidism
40. Spectrophotometers isolate a narrow band pass by means of...
purulent
<45
prisms and grating
freezing point
41. Phenobarbital is a metabolite of...
peptide bonds
attaching them to protein molecules
freezing point
primidone
42. A 45-year-old woman complains of fatigue - heat intolerance - and hair loss. Serum thyroxine and 125I-T3 resin uptake are abnormally low. What test would confirm that this is a pituitary deficiency?
TSH
fall in pH - rise in pCO2
parathyroid hormone
9
43. In using ion-exchange chromatographicbmethods - falsely increased levels of Hgb A1c will be demonstrated in presence of...
dirty applicators
Hb S
tissue and serum levels need to reach equilibrium
200x affinity for oxygen
44. A blood gas sample was sent to the lab on ice - and a bubble was present in the syringe. The blood had been exposed to room air for at least 30 minutes. The following change in blood gases occurred...
pO2 increased HCO3 decreased
manic-depression
inclusion of smokers and nonsmokers in the study population
chemical ionization matrix
45. The most heat labile fraction of alkaline phosphatase is obtained from...
O2
whole blood can be used
bone
glass
46. A sweat chloride result of 55 mEq/L and a sweat sodium of 52 mEq/L were obtained ona patient who has a history of respiratory problems. The bestc interpretation of these results is...
LDH
methadone
monitoring the course of a known cancer
boderline results test should be repeated
47. This serum protein migrates with the beta-globulins on cellulose acetate at pH 8.6...
GFR
nondiagnostic for MS
C3 complement
WITHOUT a disease with a negative test
48. Serum anion gap is increased in patients with...
increased vasoconstriction
lactic acidosis
carbs
respiratory ACIDOSIS
49. The primary function of serum albumin in the peripheral blood is to...
20:1
A1
maintain colloidal osmotic pressure
2-log(T)
50. In a normal individual - injection of thyrotropin-releasing hormone (TRH) causes an increase in blood concentrations of this hormone
acute hepatitis
Prolactin
the same as plasma glucose
manic-depression