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Chemistry Certification

Instructions:

Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can study here.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. A condition in which erythrocyte protoporphyrin is increased is...
D
thymolpthalein monophosphate
GGT
iron deficiency anemia

2. Serum concentrations of vitamin B12 are elevated in...
21-hydroxylase deficiency
parathyroid
attaching them to protein molecules
CML

3. In the sweat test - the sweating stimulant is introduced to the skin by application of...
electric current
sharp cutoff filter
dirty electrodes
potassium dichromate in SA

4. Serum from a patient with metastatic carcinoma of the prostate was separated from the clot and stored at room temperature. The following results were obtained: Patient Reference Range Calcium: 10.8 mg/dL 8.8-10.3 mg/dL LD:420 U/L 50-150 U/L Acid phos
specimen exposure to light
nephelometry
ALP with fresh draw
GLC

5. The first step in analyzing a 24-hour urine specimen for quantitative urine protein is...
measure the total volume
GLC
bicarbonate buffer
freezing point

6. The measurement of light scattered by particles in the sample is the principle of...
nephelometry
<45
bicarbonate carbonic acid
atomic absorption

7. This chemical determination may be of help in establishing the presence of seminal fluid
chylomicrons VLDL
acid phosphatase
65
transferrin

8. A patient is admitted to the emergency room in a state of metabolic alkalosis.This would be consistent with this diagnosis?
C3 complement
high co2 and hco3
catalyze redox reactions
fetal and placenta function

9. About 90% of phenytoin is excreted in the urine as...
GLC
no decrease in serum growth hormone after 90 minutes
para-hydroxylphenyl...
@ 100

10. While performing a serum lithium determination on a flame photometer with cesium as the internal standard - the technologist noticed that there was a flickering flame. The most probable cause of this problem is...
changes in the fuel
primary hyperparathyroidism
mg/ml
attaching them to protein molecules

11. A breakdown product of hemoglobin is...
respiratory ACIDOSIS
bicarbonate carbonic acid
lithium
bilirubin

12. Hydrogen ion concentration (pH) in blood is usually determined by means of these electrodes?
glass
chemical ionization matrix
Mg
endosmosis

13. The electrophoretic pattern of a plasma sample compared with a serum sample shows a...
270
ionization of carboxyl groups (yielding a net negative charge)
bilirubin
sharp fibrinogen peak

14. The formula for calculating serum osmolality that incorporates a correction for the water content of plasma is...
measurement of absorbance at 450
endosmosis
2Na + glucose over 20 + BUN over 3
B12 deficiency

15. In electrophoretic analysis - buffers...
WITHOUT a disease with a negative test
pilocarpine
exchange of amino and keto groups
act as carriers for ions

16. The expected blood gas results for a patient in chronic renal failure would match the pattern of...
the fetus is at risk for respiratory distress
Solute moves half the distance of the solvent front
metabolic acidosis
D

17. This calcium procedure utilizes lanthanum chloride to emliminate iterfering substances
serum aliquots - one heated
atomic absorption
act as carriers for ions
run a new set of controls

18. A thick white turbid specimen was received in the laboratory labeled as pericardial fluid. A microscopic examination was performed - and the differential included 90% PMNs. The fluid is...
high carbohydrate diet for 3 days
purulent
40-50
incorrect aqueous to nonaqueous mixture

19. An electrophoretic separation of lactate dehydrogenase isoenzymes that demonstrates an elevation in LD-l and LD-2 in a "flipped" pattern is consistent with...
parathyroid hormone
exchange of amino and keto groups
591
MI

20. Magnesium carbonate is added in an iron binding capacity determination in order to...
remove excess unbound iron
emphysema
obstructive jaundice
fraction absorbed into systemic circulation

21. The ability of a procedure to measure only the component(s) it claims to measure is called...
specificity
para-hydroxylphenyl...
ionization of carboxyl groups (yielding a net negative charge)
enzyme immunoassay

22. A pH of 7.0 represents a H+ concentration of...
porphobilinogen synthetase
100nmol
decreased lecithin
effluent line is obstructed

23. The following blood gas results were obtained: pH : 7.18 PO2: 86 mm Hg PCO2: 60 mm Hg O2 saturation: 92% HCO3-: 21 mEq/L TCO2: 23 mEq/L Base excess: -8.0 mEq/L The patient's results are compatible with...
emphysema
HDL
catalyze redox reactions
2-log(T)

24. Serum anion gap is increased in patients with...
lactic acidosis
elevated lactic acid - elevated pyruvate
exposure to CO
<1%

25. The TRH (thyrotropin-releasing hormone) stimulation test is useful in assessing...
tissue and serum levels need to reach equilibrium
hyperthyroidism
pO2 increased HCO3 decreased
2Na + glucose over 20 + BUN over 3

26. A blood gas sample was sent to the lab on ice - and a bubble was present in the syringe. The blood had been exposed to room air for at least 30 minutes. The following change in blood gases occurred...
porphobilinogen synthetase
increase in total circulating T4
pO2 increased HCO3 decreased
normal - liver breakdown

27. Sixty to seventy-five percent of the plasma cholesterol is transported by...
heparin
LDL
alkaline picrate
minimize the effects of interference

28. The buffering capacity of blood is maintained by a reversible exchange process between bicarbonate and...
F
volumetric flask
chloride
specificity

29. The concentration of serum carotene is affected MOST by...
1 micromole per minute
diet
be able to detect 9/10 simple instrument malfunctions
M subunit is inactivated

30. Bioavailability of a drug refers to the...
thyroxine
fraction absorbed into systemic circulation
Solute moves half the distance of the solvent front
adding an acid stabilizer

31. A patient had the following serum results: Na+ 140 mEq/L K+ 4.0 mEq/L Glucose 95 mg/dL BUN 10 mg/dL Which osmolality is consistent with these results?
the same as plasma glucose
270
increase in total circulating T4
g/MW

32. This enzyme substrates for prostatic acid phosphatase determination results in the highest specificity
thymolpthalein monophosphate
alkaline picrate
Hb S
testing heparinized plasma

33. The main reason for suboptimal drug levels in therapeutic drug monitoring is...
manic-depression
amylase
porphyrin and porphobilinogen screen
patient noncompliance

34. In spectrophotometric determination - this is the formula for calculating the absorbance of a solution
bilirubin
intestinal malabsorption
absorptivity x light path x concentration
HPLC analysis of porpobilinogen on 24hr urine

35. The osmolality of a urine or serum specimen is measured by a change in the...
porphyrin and porphobilinogen screen
freezing point
TSH
creatinine

36. Gel filtration chromatography is used to separate...
cyclic antidepressants
cmpds based on molecular weight and size
270
HCT

37. Most chemical methods for determining total protein utilize this reaction?
3500
GGT
biuret
fall in pH - rise in pCO2

38. A patient has signs and symptoms suggestive of acromegaly. The diagnosis would be confirmed if the patient had...
have a negative charge
HCT
no decrease in serum growth hormone after 90 minutes
lactic acidosis

39. The major fraction of organic iodine in the circulation is in the form of...
inclusion of smokers and nonsmokers in the study population
para-hydroxylphenyl...
T4 by RIA
thyroxine

40. Before unconjugated bilirubin can react with Ehrlich's diazo reagent - this must be added
hepatobiliary (obstruction?)
90%
methyl alcohol
bicarbonate buffer

41. This is a characteristic shared by lactate dehydrogenase - malate dehydrogenase - isocitrate dehydrogenase - and hydroxybutyrate dehydrogenase?
testing heparinized plasma
catalyze redox reactions
D
methyl alcohol

42. As part of a hyperlipidemia screening program - the following results were obtained on a 25 year old woman 6 hours after eating:Triglycerides = 260 mg/dLCholesterol = 120 mg/dL - This is the BEST interpretation of these results?
cholesterol normal triglycerides elevated
freezing point
amylase
bone

43. Respiratory acidosis is described as a(n): ______ increase in CO2 decrease in pH
120 minutes
glycerol
21-hydroxylase deficiency
testosterone

44. The methodology based on the amount of energy absorbed by a subtance as a function of its concentration and using a specific source of the same material as the substance analyzed is...
atomic absorption
GGT
correct for variations in light intensity
O2

45. Most automated blood gas analyzers directly measure...
pH pCO2 pO2
peroxidase-like activity of hemoglobin
CK-MB
para-hydroxylphenyl...

46. A cardiac glycoside that is used in the treatment of congenital heart failure and arrhythmias by increasing the force and velocity of myocardial contraction is...
digoxin
amytriptyline 104
acute intermittent porphyria
freezing point

47. The direction in which albumin migrates (ie - toward anode or cathode) during electrophoretic separation of serum proteins - at pH 8.6 - is determined by...
digoxin
incorrect aqueous to nonaqueous mixture
ionization of carboxyl groups (yielding a net negative charge)
run a new set of controls

48. The formula for calculating the amount of moles of a chemical?
sodium potassium chloride CO2
minimize the effects of interference
g/MW
parathyroid hormone

49. In a double-beam photometer - the additional beam is used to...
multiplied by 4
endogenous triglycerides
correct for variations in light intensity
urinary free cortisol

50. Lasting serum phosphate concentration is controlled primarily by the...
32
parathyroid
B12 deficiency
591