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Test your basic knowledge |
Chemistry Certification
Start Test
Study First
Subject
:
certifications
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. A carbonate salt used to control manic-depressive disorders is...
9
act as carriers for ions
prisms and grating
lithium
2. In competitive inhibition of an enzyme reaction the...
inhibitor binds to enzyme at same site as substrate
Solute moves half the distance of the solvent front
accuracy
cysteine
3. In using ion-exchange chromatographicbmethods - falsely increased levels of Hgb A1c will be demonstrated in presence of...
testosterone
potassium dichromate in SA
Hb S
valine leucine isoleucine
4. Sixty to seventy-five percent of the plasma cholesterol is transported by...
GGT
LDL
atomic absorption
591
5. The direction in which albumin migrates (ie - toward anode or cathode) during electrophoretic separation of serum proteins - at pH 8.6 - is determined by...
amytriptyline 104
5mg higher
lower than in adults
ionization of carboxyl groups (yielding a net negative charge)
6. A 68-year-old man arrives in the emergency room with a glucose level of 722 mg/dL and serum acetone of 4+ undiluted. An arterial blood gas from this patient is likely to indicate...
endogenous triglycerides
low pH
glucose
prostate
7. Characteristic of the Bence Jones protein that is used to distinguish it from other urinary proteins is its solubility...
parathyroid hormone
hemolysis
fetal and placenta function
@ 100
8. At blood pH 7.40 what is the ratio between bicarbonate and carbonic acid?
can be used for absorbtion - partition - ion exchange - and gel permeation chromatography
binding capacity of thyroxine-binding globulin
20:1
cysteine
9. The Henderson-Hasselbalch equation
porphobilinogen screen
draw blood for glucose and discontinue test
pH = pKa + log (salt/acid)
Prolactin
10. In spectrophotometric determination - this is the formula for calculating the absorbance of a solution
hepatobiliary (obstruction?)
testing heparinized plasma
2Na + glucose over 20 + BUN over 3
absorptivity x light path x concentration
11. The following data were obtained from a cellulose acetate protein electrophoresis scan: Albumin area 75 units Gamma globulin area 30 units Total area 180 units Total protein 6.5 g/dL The gamma globulin content in g/dL is...
1.1
hepatobiliary (obstruction?)
TSH
4.5
12. The following laboratory results were obtained: Serum Calcium: Increased - Urine Calcium: Increased - Serum Phosphate: Decreased - Urine Phosphate: Increased Serum Alkaline Phosphatase: Normal or Increased These results are most compatible with...
draw blood for glucose and discontinue test
lead
100 nmol
primary hyperparathyroidism
13. Ninety percent of the copper present in plasma is bound to...
ceruplasmin
can be used for absorbtion - partition - ion exchange - and gel permeation chromatography
increased vasoconstriction
urobilin
14. The main reason for suboptimal drug levels in therapeutic drug monitoring is...
200
patient noncompliance
100 nmol
manic-depression
15. In the immunoinhibition phase of the CK-MB procedure...
M subunit is inactivated
chloride
cmpds based on molecular weight and size
can be used for absorbtion - partition - ion exchange - and gel permeation chromatography
16. Technical problems encountered during the collection of an amniotic fluid specimen caused doubt as to whether the specimen was amniotic in origin. This procedure would establish that the fluid is amniotic in origin
dirty applicators
creatinine
prevent phosphate interference
BUN 80
17. Which two conditions can "physiologically" elevate serum alkaline phosphatase?
growth - third trimester of pregnancy
chylomicrons
1 micromole per minute
32
18. Bioavailability of a drug refers to the...
ionic charge
fraction absorbed into systemic circulation
analyzed immediately
enzyme induction
19. A 9-month-old boy from Israel has gradually lost the ability to sit up and develops seizures. He has an increased amount of a phospholipid called GM2-ganglioside in his neurons - and he lacks the enzyme hexosaminidase A in his leukocytes. These findi
incorrect aqueous to nonaqueous mixture
Tay-sachs
urobilin
prostate
20. The anticonvulsant used to control tonic-clonic (grand mal) seizures is...
phenytoin
glycerol
prostate
patient noncompliance
21. The following data were obtained on amniotic fluid from a gestation of 36 weeks' duration by menstrual dates: L/S = 2 Phosphatidyl glycerol not present This can be concluded from these data?
the fetus is at risk for respiratory distress
BUN 80
inhibitor binds to enzyme at same site as substrate
cholesterol normal triglycerides elevated
22. This is a characteristic shared by lactate dehydrogenase - malate dehydrogenase - isocitrate dehydrogenase - and hydroxybutyrate dehydrogenase?
benzoylecogine
catalyze redox reactions
is quantitated by the amount of light produced
LDL
23. A blood gas sample was sent to the lab on ice - and a bubble was present in the syringe. The blood had been exposed to room air for at least 30 minutes. The following change in blood gases occurred...
pO2 increased HCO3 decreased
32
chylomicrons VLDL
wavelength
24. Total iron-binding capacity measures the serum iron transporting capacity of...
transferrin
can be separated into distinct phenotypes
carbs
chloride
25. The normal concentration of proteins in cerebrospinal fluid - relative to serum protein - is...
wavelength
impaired response to ACTH stimulation
cysteine
<1%
26. The regulation of calcium and phosphorus metabolism is accomplished by which gland?
parathyroid
show a decrease in glycosylated hgb
endogenous triglycerides
remove excess unbound iron
27. The biuret reaction for the analysis of serum protein depends on the number...
prostate
peptide bonds
incorrect aqueous to nonaqueous mixture
spun separated iced and tested immediately
28. A patient with type I insulin-dependent diabetes mellitus has the following results: Fasting blood glucose: 150 mg/dL (70-110 rng/dL) Hemoglobin A1c: 25% (6.0%-19.5%) Fructosamine: 3.0 mmol/L ( 2.0-5.3 mmol/L)
Tangier
improving state of metabolic control (as indicated by fructosamine)
CO2
digoxin
29. Stray light can be detected in a spectrophotometer by utilizing a...
sharp cutoff filter
conjugated hyperbilirubinemia - hepatocellular obstruction
viral hepatitis
<1%
30. This 2-hour postprandial glucose values demonstrates unequivocal hyperglycemia diagnostic for diabetes mellitus
pO2 increased HCO3 decreased
200
lead
Tangier
31. In respiratory acidosis - a compensatory mechanism is the increase in...
cancel test
porphobilinogen synthetase
plasma bicarbonate
the fetus is at risk for respiratory distress
32. A patient in her 33rd week of pregnancy is hospitalized with toxemia. Her doctor would like to deliver the baby early because the toxemia is becoming more severe. The baby's best chance of delivery without respiratory distress due to lung immaturity
CK
HDL
brain
L/S ratio > 3.5
33. The preparation of a patient for standard tolerance testing should include...
elevated lactic acid - elevated pyruvate
1 micromole per minute
enzyme immunoassay
high carbohydrate diet for 3 days
34. Aminotransferase enzymes catalyze the...
C3 complement
exchange of amino and keto groups
metabolic acidosis
effluent line is obstructed
35. One international unit of enzyme activity is the amount of enzyme that - under specified reaction conditions of substrate concentration - pH - and temperature - causes utilization of substrate at the rate of...
CK
one micromole/minute
LDL
catalyze redox reactions
36. The enzyme that exists chiefly in skeletal muscle - heart - and brain; is grossly elevated in active muscular dystrophy; and rises early in myocardial infarction is...
5
Hb S
creatine kinase
sample exposed to light
37. Diagnostic specificity is defined as the percentage of individuals...
prostate
acid phosphatase
without a disease with a negative test result
creatinine clearance
38. The following results were obtained in a creatinine clearance evaluation: Urine concentration 84 mg/dL Urine volume 1440 mL/24 hr Serum concentration 1.4 mg/dL Body surface area 1.60 m2 (average = 1.73 m2) The creatinine cle~trance in mL/min is...
BUN 80
enzyme induction
hemolysis
65
39. Bile acid concentrations are useful to assess...
1.9
hepatobiliary (obstruction?)
exposure to CO
sodium
40. Measurement of the serum acid phosphatase is used to detect neoplastic disease of the...
Tangier
5
parathyroid hormone
prostate
41. Beriberi is associated with deficiency of...
LDH
lead
volumetric flask
thiamine
42. Clinical assays for tumor markers are the most important for...
is quantitated by the amount of light produced
draw blood for glucose and discontinue test
acute hepatitis
monitoring the course of a known cancer
43. Given the following values:100;120;150;140;130;What is the mean?
fraction absorbed into systemic circulation
dirty applicators
cysteine
128
44. Serum from a patient with metastatic carcinoma of the prostate was separated from the clot and stored at room temperature. The following results were obtained: Patient Reference Range Calcium: 10.8 mg/dL 8.8-10.3 mg/dL LD:420 U/L 50-150 U/L Acid phos
CO2
ALP with fresh draw
M subunit is inactivated
metabolic acidosis
45. An HPLC operator notes that the column pressure is too high - is rising too rapidly - and the recorder output is not producing normal peaks. The most probable cause of the problem is...
dihydroxyacetone side chain
there is an absence of correlation
GGT
effluent line is obstructed
46. The most heat labile fraction of alkaline phosphatase is obtained from...
para-hydroxylphenyl...
bone
fraction absorbed into systemic circulation
carbs
47. A condition in which erythrocyte protoporphyrin is increased is...
iron deficiency anemia
NADH
acute hepatitis
sample exposed to light
48. Certain enzymes are activated to metabolize drugs as a result of another drug action. This is referred to as...
hepatobiliary (obstruction?)
270
enzyme induction
HCT
49. A patient has the following results: Patient Values : Reference Values: Serum iron 250 ug/dL 60-150 ug/dL TIBC 350 ug/dL 300-35O ug/dL The best conclusion is that this patient has...
iron hemochromatosis
parathyroid
sodium
bone
50. An emphysema patient suffering from fluid accumulation in the alveolar spaves is likely to be in what metabolic state?
respiratory ACIDOSIS
inhibitor binds to enzyme at same site as substrate
normal - liver breakdown
endogenous triglycerides