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Chemistry Certification
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Subject
:
certifications
Instructions:
Answer 50 questions in 15 minutes.
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.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. A 9-month-old boy from Israel has gradually lost the ability to sit up and develops seizures. He has an increased amount of a phospholipid called GM2-ganglioside in his neurons - and he lacks the enzyme hexosaminidase A in his leukocytes. These findi
intestinal malabsorption
fresh morning urine for delta-aminolevulinic acid
Tay-sachs
band width
2. About 90% of phenytoin is excreted in the urine as...
para-hydroxylphenyl...
specificity
metabolic acidosis
21-hydroxylase deficiency
3. Turbidity in serum suggests elevation of...
normal - liver breakdown
endogenous triglycerides
chylomicrons
100 nmol
4. The buffering capacity of blood is maintained by a reversible exchange process between bicarbonate and...
chloride
creatinine
4.5
fraction absorbed into systemic circulation
5. Serum from a patient with metastatic carcinoma of the prostate was separated from the clot and stored at room temperature. The following results were obtained: Patient Reference Range Calcium: 10.8 mg/dL 8.8-10.3 mg/dL LD:420 U/L 50-150 U/L Acid phos
ALP with fresh draw
placenta
21-hydroxylase deficiency
one micromole/minute
6. The normal concentration of proteins in cerebrospinal fluid - relative to serum protein - is...
iron hemochromatosis
transferrin
T4 by RIA
<1%
7. A serum potassium is 19.5 mg/100 mL. This value is equal to how many mEq/L (MW of K = 39)?
porphobilinigen SCREEN
5
remove excess unbound iron
no ice clots bubbles
8. Fluctuation of the needle on a coulometric type titrator is most probably due to...
specificity
serum cortisol > 15
dirty electrodes
thiamine
9. A patient with malabsorption receives 25 g of d-xylose orally; during the subsequent 5-hour period - the urine excretion of d-xylose is less than 3 g. This would indicate...
intestinal malabsorption
32
primidone
cmpds based on molecular weight and size
10. A blood sample was received from the emergency room with a request for narcotic analysis. The request slip indicated that the patient (a known heroin addict) responded to naloxone administration. The serum was negative for morphine by EIA. What other
remove excess unbound iron
benzoylecogine
effluent line is obstructed
methadone
11. A common cause of respiratory alkalosis is...
breast cancer
amytriptyline 104
enzyme immunoassay
hyperventilation
12. A 21-year-old man with nausea - vomiting - and jaundice has the following laboratory findings: Total serum bilirubin level: 8.5 mg/dL (normal - 0-1.0) Conjugated serum bilirubin level: 6.1 mg/dL (normal - 0-0.5) Urine urobilinogen: Increased Fecal u
glucose
freezing point
conjugated hyperbilirubinemia - hepatocellular obstruction
valine leucine isoleucine
13. Total iron-binding capacity measures the serum iron transporting capacity of...
adding an acid stabilizer
acute intermittent porphyria
lactic acidosis
transferrin
14. The most heat labile fraction of alkaline phosphatase is obtained from...
freezing point
heparin
bone
glucose
15. Serum concentrations of vitamin B12 are elevated in...
L/S ratio > 3.5
there is an absence of correlation
CML
parathyroid
16. This applies to cryoscopic osmometry
amylase and lipase
CK-MB
Temperature is a function of the number of particles in solution
enzyme induction
17. Maple syrup urine disease is characterized by an increase in this urinary amino acids
Calcium - phosphorus
maintain colloidal osmotic pressure
metabolic acidosis
valine leucine isoleucine
18. This lipid results would be expected to be falsely elevated on a serum specimen from a nonfasting patient
fall in pH - rise in pCO2
lipase
GLC
trig
19. In automated methods utilizing a bichromatic analyzer - dual wavelengths are employed to...
immunofixation
Mg
minimize the effects of interference
exposure to CO
20. Isoenzyme assays are preformed to improve...
20:1
specificity
HDL
corticosterone
21. The unit of measure for a standard solution is...
BUN increased
urobilin
mg/ml
adding an acid stabilizer
22. A critically ill patient becomes comatose. The physician believes the coma is due to hepatic failure. The assay most helpful in this diagnosis is...
ammonia
cyclic antidepressants
120 minutes
transferrin
23. The formation of estriol in a pregnant woman is dependent on...
fetal and placenta function
diet
porphobilinigen SCREEN
20:1
24. The primary function of serum albumin in the peripheral blood is to...
maintain colloidal osmotic pressure
exchange of amino and keto groups
porphobilinogen synthetase
parathyroid
25. The anion gap is useful for quality control of laboratory results for...
glycerol
ratio of distance moved by solvent to distance moved by compound
CK-MB
sodium potassium chloride CO2
26. In using ion-exchange chromatographicbmethods - falsely increased levels of Hgb A1c will be demonstrated in presence of...
phenytoin
boderline results test should be repeated
Hb S
thiamine
27. Oligoclonal bands are present on electrophoresis of concentrated CSF and also on concurrently tested serum of the same patient. The proper interpretation is...
wavelength
nondiagnostic for MS
purulent
hyperventilation
28. The formula for calculating absorbance given the percent transmittance (%T) of a solution
sharp fibrinogen peak
CK-MB
WITHOUT a disease with a negative test
2-log(T)
29. The definitive diagnosis of primary adrenal insufficiency requires demonstration of...
20:1
Temperature is a function of the number of particles in solution
D
impaired response to ACTH stimulation
30. The test for adrenal cortical hyperfunction that has the greatest diagnostic sensitivity is measurement of...
incorrect aqueous to nonaqueous mixture
ionization of carboxyl groups (yielding a net negative charge)
ALP with fresh draw
urinary free cortisol
31. A blood gas sample was sent to the lab on ice - and a bubble was present in the syringe. The blood had been exposed to room air for at least 30 minutes. The following change in blood gases occurred...
pO2 increased HCO3 decreased
pilocarpine
methyl alcohol
thiamine
32. In an internal standard flame photometer - the internal standard is used to...
correct for variations in flame and atomizer
dirty electrodes
measurement of absorbance at 450
200x affinity for oxygen
33. Most most likely to be ordered in addition to serum calcium to determine the cause of tetany?
Mg
bone
cmpds based on molecular weight and size
urobilin
34. This diseases results from a familial absence of high-density lioprotein
run a new set of controls
Tangier
acute intermittent porphyria
creatine kinase
35. A true statement about high performance liquid chromatography (HPLC) is that it...
BUN increased
purulent
A1
can be used for absorbtion - partition - ion exchange - and gel permeation chromatography
36. Magnesium carbonate is added in an iron binding capacity determination in order to...
remove excess unbound iron
no ice clots bubbles
bone
hyperthyroidism
37. An automated method for measuring chloride that generates silver ions in the reaction is...
ionization of carboxyl groups (yielding a net negative charge)
coulometry
parathyroid hormone
creatinine
38. Alkaline phosphatase Slight increase - Aminotransferase Marked increase - Aspartate aminotransferase Marked increase - Alanine gamma-glutamyl transferase Slight increase
sodium potassium chloride CO2
acute hepatitis
ceruplasmin
transferrin
39. The first step to be taken when attempting to repair a piece of electronic equipment is...
turn off
(testing of urine for) delta-am.. acid
hemolysis
Temperature is a function of the number of particles in solution
40. Most chemical methods for determining total protein utilize this reaction?
fresh morning urine for delta-aminolevulinic acid
creatinine clearance
biuret
attaching them to protein molecules
41. Enzymes used in the diagnosis of acute pancreatitis?
freezing point
GFR
amylase and lipase
manic-depression
42. A new method is being evaluated. A recovery experiment is performed with the following results: 0.9 mL serum sample + 0.1 mL H20 = 89 mEq/L 0.9 mL serum sample + 0.1 mL analyte std. @ 800 mEq/L = 161 mEq/L The percent recovery of the added analyt
fraction absorbed into systemic circulation
creatinine
90%
9
43. What substance gives feces its normal color?
specimen exposure to light
NADH
urobilin
BUN 80
44. This steroid is an adrenal cortical hormone
measure the total volume
cancel test
corticosterone
amylase
45. The following blood gas results were obtained: pH : 7.18 PO2: 86 mm Hg PCO2: 60 mm Hg O2 saturation: 92% HCO3-: 21 mEq/L TCO2: 23 mEq/L Base excess: -8.0 mEq/L The patient's results are compatible with...
sodium
chloride
porphobilinogen synthetase
emphysema
46. Nephelometers measure light...
CK
didymium filter
scattered at a right angle
para-hydroxylphenyl...
47. This method employs a highly specific antibody to thyroxine
WITHOUT a disease with a negative test
T4 by RIA
manic-depression
TSH
48. As part of a hyperlipidemia screening program - the following results were obtained on a 25 year old woman 6 hours after eating:Triglycerides = 260 mg/dLCholesterol = 120 mg/dL - This is the BEST interpretation of these results?
band width
occult blood
cyclic antidepressants
cholesterol normal triglycerides elevated
49. These enzymes of heme biosynthesis are inhibited by lead
porphobilinogen synthetase
9
phenytoin
primidone
50. The protein portion of an enzyme complex is called the...
thyroxine binding globulin
bilirubindiglucuronide
apoenzyme
brain
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