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Chemistry Certification
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Subject
:
certifications
Instructions:
Answer 50 questions in 15 minutes.
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.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. The following laboratory results were obtained on arterial blood: Sodium 136 mEq/L pH 7.32 Potassium 4.4 mEq/L PCO2 79 mm Hg Chloride 92 mEq/L Bicarbonate 40 mEq/L These results are most compatible with...
glucose
respiratory acidosis
no ice clots bubbles
scattered at a right angle
2. In a normal individual - injection of thyrotropin-releasing hormone (TRH) causes an increase in blood concentrations of this hormone
Prolactin
HPLC analysis of porpobilinogen on 24hr urine
serum aliquots - one heated
amytriptyline 104
3. The hemoglobin that is resistant to alkali (KOH) denaturation is...
L/S ratio > 3.5
F
parathyroid
<45
4. Four children are admitted with malaise - anorexia - and abdominal pain. Further evaluations reveal mild anemia - erythrocyte basophilic stippling - and profound pica habits. Poisoning by which heavy metal is most likely responsible?
HPLC analysis of porpobilinogen on 24hr urine
lead
iron hemochromatosis
L/S ratio > 3.5
5. Currently the most common method for specific identification and quantitation of serum barbiturates is...
run a new set of controls
urobilin
thymolpthalein monophosphate
GLC
6. A 45-year-old woman has a fasting serum glucose concentration of 95 mg/dL and a 2-hour postprandial glucose concentration of 105 mg/dL. The statement that best describes this patient's fasting serum glucose concentration is...
fraction absorbed into systemic circulation
enzyme immunoassay
D
normal - liver breakdown
7. The following data were obtained on amniotic fluid from a gestation of 36 weeks' duration by menstrual dates: L/S = 2 Phosphatidyl glycerol not present This can be concluded from these data?
volumetric flask
can be separated into distinct phenotypes
L/S ratio > 3.5
the fetus is at risk for respiratory distress
8. One means of checking a spectrophotometer wavelength calibration in the visible range is by using a...
primary hyperparathyroidism
chloride
increase in total circulating T4
didymium filter
9. Gas chromatography with the nitrogen/phosphorus detector is the most commonly used technique for the analysis of...
cyclic antidepressants
@ 100
Mg
g/MW
10. An electrophoretic separation of lactate dehydrogenase isoenzymes that demonstrates an elevation in LD-l and LD-2 in a "flipped" pattern is consistent with...
attaching them to protein molecules
90%
diet
MI
11. Analysis of erythrocytes for uroporphyrinogen I synthetase detects...
cmpds based on molecular weight and size
acute intermittent porphyria
show a decrease in glycosylated hgb
atomic absorption
12. In amniotic fluid - the procedure used to detect Rh isosensitization is...
measurement of absorbance at 450
show a decrease in glycosylated hgb
occult blood
quantitation of label
13. The greatest activities of serum AST and ALT are seen in...
remove excess unbound iron
porphobilinogen screen
acute hepatitis
quantitation of label
14. Quantitation of NA+ and K+ by ion-selective electrode is more rapid than flame photometry because...
spun separated iced and tested immediately
phenytoin
whole blood can be used
specimen exposure to light
15. In performing a spinal fluid protein determination - the specimen is diluted 1 part spinal fluid to 3 parts saline to obtain a result low enough to measure. To calculate the protein concentration the result must be...
multiplied by 4
amylase and lipase
iron hemochromatosis
hepatobiliary (obstruction?)
16. A 68-year-old man arrives in the emergency room with a glucose level of 722 mg/dL and serum acetone of 4+ undiluted. An arterial blood gas from this patient is likely to indicate...
specificity
properties of the membrane
low pH
inclusion of smokers and nonsmokers in the study population
17. Ninety percent of the copper present in plasma is bound to...
5
methyl alcohol
low pH
ceruplasmin
18. 4 mL of water is added to 1 mL of serum. This represents this serum dilutions
valine leucine isoleucine
there is an absence of correlation
primary hyperparathyroidism
1:5
19. Alkaline phosphatase Slight increase - Aminotransferase Marked increase - Aspartate aminotransferase Marked increase - Alanine gamma-glutamyl transferase Slight increase
no ice clots bubbles
elevated lactic acid - elevated pyruvate
acute hepatitis
creatinine
20. An automated CK assay gives a reading that is above the limits of linearity. A dilution of the serum sample is made by adding 1 mL of serum to 9 mL of water. The instrument now rew 350 U/L. The correct report on the undiluted serum should be...
bone
1.1
act as carriers for ions
3500
21. The primary function of serum albumin in the peripheral blood is to...
MI
atomic absorption
nephelometry
maintain colloidal osmotic pressure
22. The protein portion of an enzyme complex is called the...
spun separated iced and tested immediately
apoenzyme
carbohydrate hyperalimentation
pH pCO2 pO2
23. An Rf value of 0.5 in thin-layer chromatography means...
65
methadone
Solute moves half the distance of the solvent front
maintain colloidal osmotic pressure
24. The anticonvulsant used to control tonic-clonic (grand mal) seizures is...
Prolactin
phenytoin
enzyme immunoassay
120 minutes
25. An automated method for measuring chloride that generates silver ions in the reaction is...
parathyroid hormone
coulometry
atomic absorption
WITHOUT a disease with a negative test
26. Acidosis and alkalosis are best defined as fluctuations in blood pH and CO2 content due to changes in...
placenta
bicarbonate buffer
peroxidase-like activity of hemoglobin
Hb S
27. The formula for calculating serum osmolality that incorporates a correction for the water content of plasma is...
2Na + glucose over 20 + BUN over 3
thymolpthalein monophosphate
TSH
ionization of carboxyl groups (yielding a net negative charge)
28. Aminotransferase enzymes catalyze the...
sharp cutoff filter
atomic absorption
normal - liver breakdown
exchange of amino and keto groups
29. An increase in serum acetone is indicative of a defect in the metabolism of...
T4 by RIA
carbs
acute intermittent porphyria
A1
30. This would be an example of a glucose-specific colorimetric method
plasma bicarbonate
absorptivity x light path x concentration
cancel test
glucose oxidase
31. Calcium concentration in the serum is regulated by...
1:5
urinary free cortisol
standard
parathyroid hormone
32. A patient with hemolytic anemia will...
acute intermittent porphyria
show a decrease in glycosylated hgb
testosterone
GLC
33. Most chemical methods for determining total protein utilize this reaction?
biuret
D
TSH
T4 by RIA
34. This is a glycolytic enzyme that catalyzes the cleavage of fructose-1 - 6-diphosphate to glyceraldehyde-3-phosphate and dihydroxyacetone phosphate
bilirubindiglucuronide
pituitary
chylomicrons
aldolase
35. The reason carbon monoxide is so toxic is because it...
spun separated iced and tested immediately
200x affinity for oxygen
@ 100
cancel test
36. A common cause of respiratory alkalosis is...
chloride
urobilin
digoxin
hyperventilation
37. The enzyme that exists chiefly in skeletal muscle - heart - and brain; is grossly elevated in active muscular dystrophy; and rises early in myocardial infarction is...
endosmosis
creatine kinase
Tay-sachs
ammonia
38. A reciprocal relationship exists between...
Calcium - phosphorus
A1c
high co2 and hco3
glucose oxidase
39. Specimens for blood gas determination should be drawn into a syringe containing...
increased vasoconstriction
pH pCO2 pO2
heparin
cyclic antidepressants
40. A fasting serum sample from an asymptomatic 43-year-old woman is examined visually chemically with the following results: Initial appearance of serum: Milky Appearance of serum after overnight refrigeration: Cream layer over turbid serum Triglyceri
chylomicrons VLDL
chloride
carbs
pilocarpine
41. Spectrophotometers isolate a narrow band pass by means of...
prisms and grating
effluent line is obstructed
atomic absorption
act as carriers for ions
42. At a pH of 8.6 the gamma globulins move toward the cathode - despite the fact that they are negatively charged. What is this phenomenon called?
can be used for absorbtion - partition - ion exchange - and gel permeation chromatography
fraction absorbed into systemic circulation
endosmosis
L/S ratio > 3.5
43. This enzymes catalyzes the conversion of starch to glucose and maltose
amylase
GFR
respiratory acidosis
alkaline picrate
44. About 90% of phenytoin is excreted in the urine as...
5 tri 15 cholesterol 50 protein
Wilson's disease
para-hydroxylphenyl...
act as carriers for ions
45. Respiratory acidosis is described as a(n): ______ increase in CO2 decrease in pH
the fetus is at risk for respiratory distress
quantitation of label
biuret
glycerol
46. This applies to cryoscopic osmometry
chloride
Temperature is a function of the number of particles in solution
Tay-sachs
testing heparinized plasma
47. Beriberi is associated with deficiency of...
thiamine
endosmosis
increased O2 decreased HCO3
chylomicrons
48. Blood was collected in a serum separator tube from a patient who had been fasting since midnight. The time of collection was 7:00 AM. The laboratory test that should be re-collected is...
triglycerides
properties of the membrane
HDL
carbs
49. A pH of 7.0 represents a H+ concentration of...
GFR
100nmol
adding an acid stabilizer
porphobilinigen SCREEN
50. Lithium therapy is widely used in the treatment of...
manic-depression
the fetus is at risk for respiratory distress
ionic charge
D
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