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Test your basic knowledge |
Chemistry Certification
Start Test
Study First
Subject
:
certifications
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. 4 mL of water is added to 1 mL of serum. This represents this serum dilutions
pituitary
TLC
1:5
ALP with fresh draw
2. A serum sample for acid phosphatase determination is best prepared for room temperature storage by...
ionization of carboxyl groups (yielding a net negative charge)
adding an acid stabilizer
lower than in adults
emphysema
3. The following blood gas results were obtained: pH : 7.18 PO2: 86 mm Hg PCO2: 60 mm Hg O2 saturation: 92% HCO3-: 21 mEq/L TCO2: 23 mEq/L Base excess: -8.0 mEq/L The patient's results are compatible with...
MI
growth - third trimester of pregnancy
carbohydrate hyperalimentation
emphysema
4. Analysis of erythrocytes for uroporphyrinogen I synthetase detects...
acute intermittent porphyria
methadone
128
minimize the effects of interference
5. Lithium therapy is widely used in the treatment of...
fresh morning urine for delta-aminolevulinic acid
A1c
manic-depression
porphyrin and porphobilinogen screen
6. The ability of a procedure to measure only the component(s) it claims to measure is called...
L/S ratio > 3.5
quantitation of label
specificity
have a negative charge
7. An electrode has a silver/silver chloride anode and a platinum wire cathode. It is suspended in KCl solution and separated from the blood to be analyzed by a selectively permeable membrane. Such an electrode is used to measure...
g/MW
porphobilinigen SCREEN
O2
D
8. Most chemical methods for determining total protein utilize this reaction?
lead
biuret
patient noncompliance
cancel test
9. Bile acid concentrations are useful to assess...
can be separated into distinct phenotypes
hepatobiliary (obstruction?)
128
lithium
10. A technician is asked by the supervisor to prepare a standard solution from the stock standard. What is the glassware of choice for this solution?
pH = pKa + log (salt/acid)
ammonia
volumetric flask
monitoring the course of a known cancer
11. Thiis serum protein fraction is most likely to be elevated in patients with nephrotic syndrome?
2-log(T)
specificity
iron deficiency anemia
alpha 2 beta
12. Serum anion gap is increased in patients with...
1.1
specimen exposure to light
lactic acidosis
nondiagnostic for MS
13. A chemiluminescent EIA...
is quantitated by the amount of light produced
128
amytriptyline 104
metabolic acidosis
14. Blood specimens for digoxin assays should be obtained between 8 hours or more after drug administration because...
acute hepatitis
breast cancer
tissue and serum levels need to reach equilibrium
viral hepatitis
15. This method employs a highly specific antibody to thyroxine
act as carriers for ions
obstructive jaundice
T4 by RIA
aldolase
16. Acidosis and alkalosis are best defined as fluctuations in blood pH and CO2 content due to changes in...
bicarbonate buffer
immunofixation
TSH
primidone
17. An electrophoretic separation of lactate dehydrogenase isoenzymes that demonstrates an elevation in LD-l and LD-2 in a "flipped" pattern is consistent with...
occult blood
MI
<45
growth - third trimester of pregnancy
18. A patient with type I insulin-dependent diabetes mellitus has the following results: Fasting blood glucose: 150 mg/dL (70-110 rng/dL) Hemoglobin A1c: 25% (6.0%-19.5%) Fructosamine: 3.0 mmol/L ( 2.0-5.3 mmol/L)
thymolpthalein monophosphate
brain
maintain colloidal osmotic pressure
improving state of metabolic control (as indicated by fructosamine)
19. The T3 resin uptake test is a measure of...
specificity
binding capacity of thyroxine-binding globulin
there is an absence of correlation
agarose
20. Ninety percent of the copper present in plasma is bound to...
changes in the fuel
one micromole/minute
ceruplasmin
high co2 and hco3
21. The most sensitive enzymatic indicator for liver damage from ethanol intake is...
plasma bicarbonate
biuret
run a new set of controls
GGT
22. The identification of Bence Jones protein is best accomplished by...
immunofixation
chylomicrons
prevent phosphate interference
cholesterol normal triglycerides elevated
23. A patient is admitted with biliary cirrhosis. If a serum protein electrophoresis is preformed - these globulin fractions will be most elevated?
faster than gamma
lithium
exchange of amino and keto groups
beta
24. In performing a spinal fluid protein determination - the specimen is diluted 1 part spinal fluid to 3 parts saline to obtain a result low enough to measure. To calculate the protein concentration the result must be...
fall in pH - rise in pCO2
hemolysis
multiplied by 4
endosmosis
25. As part of a hyperlipidemia screening program - the following results were obtained on a 25 year old woman 6 hours after eating:Triglycerides = 260 mg/dLCholesterol = 120 mg/dL - This is the BEST interpretation of these results?
cholesterol normal triglycerides elevated
accuracy
minimize the effects of interference
100nmol
26. A patient with glomerulonephritis would present the following serum results...
inclusion of smokers and nonsmokers in the study population
BUN increased
prostate
340
27. The normal concentration of proteins in cerebrospinal fluid - relative to serum protein - is...
have a negative charge
carbohydrate hyperalimentation
<1%
increased O2 decreased HCO3
28. The urea nitrogen concentration of a serum sample was measured as 15 mg/dL (atomic weights: carbon = 12 - oxygen = 16 - nitrogen = 14 - hydrogen = 1). The urea concentration of the same sample - in mg/dL - is...
hemolysis
32
100 nmol
iron deficiency anemia
29. Regan isoenzyme has the same properties as alkaline phosphatase that originates in the...
properties of the membrane
low pH
placenta
methadone
30. Major actions of angiotensin II include...
increased vasoconstriction
pH = pKa + log (salt/acid)
ratio of distance moved by solvent to distance moved by compound
fraction absorbed into systemic circulation
31. An automated CK assay gives a reading that is above the limits of linearity. A dilution of the serum sample is made by adding 1 mL of serum to 9 mL of water. The instrument now rew 350 U/L. The correct report on the undiluted serum should be...
3500
Tangier
pH = pKa + log (salt/acid)
adding an acid stabilizer
32. A fresh urine sample is received for "porphyrins" or "porphyria" without further information or specifications. Initial analysis should include...
porphyrin and porphobilinogen screen
TLC
primidone
tissue and serum levels need to reach equilibrium
33. Upon completion of a run of cholesterol tests - the technician recognizes that the controls are not within the two standard deviations confidence range. What is the appropriate course of action?
is quantitated by the amount of light produced
run a new set of controls
1 micromole per minute
porphyrin and porphobilinogen screen
34. In developing the reference for a new EIA for CEA - the range for the normal population was broader than that published by the vendor. Controls are acceptable with a narrow coefficient of variation. This may be explained by...
inclusion of smokers and nonsmokers in the study population
peptide bonds
specificity
bilirubin
35. Upon completion of a run of cholesterol tests - the technician recognizes that the controls are not within the two standard deviations confidence range. What is the appropriate course of action
thyroxine binding globulin
lead
run a new set of controls
have a negative charge
36. The biuret reaction for the analysis of serum protein depends on the number...
SD over mean
thyroxine
peptide bonds
0
37. Quantitation of NA+ and K+ by ion-selective electrode is more rapid than flame photometry because...
whole blood can be used
120 minutes
Hb S
chloride
38. The major fraction of organic iodine in the circulation is in the form of...
glucose oxidase
4.5
thyroxine
didymium filter
39. This calcium procedure utilizes lanthanum chloride to emliminate iterfering substances
340
parathyroid hormone
respiratory acidosis
atomic absorption
40. The following bilirubin results are obtained on a patient: Day 1: 4.3 mg/dL Day 4: 2.2 mg/dL Day 2: 4.6 mg/dL Day 5: 4.4 mg/dL Day 3: 4.5 mg/dL Day 6: 4.5 mg/dL - Given that the controls were within range each day - what is a probable explanation for
specimen exposure to light
F
primidone
heparin
41. The following results were obtained in a creatinine clearance evaluation: Urine concentration 84 mg/dL Urine volume 1440 mL/24 hr Serum concentration 1.4 mg/dL Body surface area 1.60 m2 (average = 1.73 m2) The creatinine cle~trance in mL/min is...
dirty applicators
65
atomic absorption
transferrin
42. Blood was collected in a serum separator tube from a patient who had been fasting since midnight. The time of collection was 7:00 AM. The laboratory test that should be re-collected is...
inclusion of smokers and nonsmokers in the study population
triglycerides
whole blood can be used
glucose tolerance test
43. A patient with hemolytic anemia will...
show a decrease in glycosylated hgb
maintain colloidal osmotic pressure
testing heparinized plasma
viral hepatitis
44. This serum protein migrates with the beta-globulins on cellulose acetate at pH 8.6...
increased vasoconstriction
ionic charge
changes in the fuel
C3 complement
45. The test for adrenal cortical hyperfunction that has the greatest diagnostic sensitivity is measurement of...
urinary free cortisol
thiamine
sodium potassium chloride CO2
BUN 80
46. In electrophoretic analysis - buffers...
creatinine clearance
act as carriers for ions
boderline results test should be repeated
fetal and placenta function
47. A person suspected of having metabolic alkalosis would have these laboratory findings
placenta
cancel test
one micromole/minute
CO2 and pH elevated
48. At blood pH 7.40 what is the ratio between bicarbonate and carbonic acid?
attaching them to protein molecules
20:1
Solute moves half the distance of the solvent front
prisms and grating
49. This method offers the greatest sensitivity for HBsAg testing
GFR
enzyme immunoassay
emphysema
ionization of carboxyl groups (yielding a net negative charge)
50. In using ion-exchange chromatographicbmethods - falsely increased levels of Hgb A1c will be demonstrated in presence of...
turn off
Hb S
monitoring the course of a known cancer
CO2