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Test your basic knowledge |
Chemistry Certification
Start Test
Study First
Subject
:
certifications
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. A patient has signs and symptoms suggestive of acromegaly. The diagnosis would be confirmed if the patient had...
aldolase
run a new set of controls
no decrease in serum growth hormone after 90 minutes
enzyme induction
2. While performing a serum lithium determination on a flame photometer with cesium as the internal standard - the technologist noticed that there was a flickering flame. The most probable cause of this problem is...
carbohydrate hyperalimentation
CML
porphobilinigen SCREEN
changes in the fuel
3. The direction in which albumin migrates (ie - toward anode or cathode) during electrophoretic separation of serum proteins - at pH 8.6 - is determined by...
ionization of carboxyl groups (yielding a net negative charge)
apoenzyme
glass
chloride
4. Maple syrup urine disease is characterized by an increase in this urinary amino acids
valine leucine isoleucine
biuret
parathyroid
D
5. The most widely employed screening technique for drug abuse is...
TLC
lower than in adults
3500
catalyze redox reactions
6. Ninety percent of the copper present in plasma is bound to...
ceruplasmin
inclusion of smokers and nonsmokers in the study population
HDL
40-50
7. A patient with type I insulin-dependent diabetes mellitus has the following results: Fasting blood glucose: 150 mg/dL (70-110 rng/dL) Hemoglobin A1c: 25% (6.0%-19.5%) Fructosamine: 3.0 mmol/L ( 2.0-5.3 mmol/L)
properties of the membrane
biuret
improving state of metabolic control (as indicated by fructosamine)
L/S ratio > 3.5
8. The serum glucose concentration of a diabetic patient undergoing a 2-hour glucose tolerance test should return to the baseline (fasting level) after a minimum of...
draw blood for glucose and discontinue test
respiratory acidosis
120 minutes
lactic acidosis
9. The buffering capacity of blood is maintained by a reversible exchange process between bicarbonate and...
run a new set of controls
there is an absence of correlation
chloride
120 minutes
10. The anticonvulsant used to control tonic-clonic (grand mal) seizures is...
phenytoin
40-50
A1c
CK-MB
11. A new method is being evaluated. A recovery experiment is performed with the following results: 0.9 mL serum sample + 0.1 mL H20 = 89 mEq/L 0.9 mL serum sample + 0.1 mL analyte std. @ 800 mEq/L = 161 mEq/L The percent recovery of the added analyt
90%
coulometry
without a disease with a negative test result
D
12. Fluctuation of the needle on a coulometric type titrator is most probably due to...
dirty electrodes
volumetric flask
elevated lactic acid - elevated pyruvate
carbohydrate hyperalimentation
13. In respiratory acidosis - a compensatory mechanism is the increase in...
electric current
sodium
plasma bicarbonate
serum cortisol > 15
14. Serum anion gap is increased in patients with...
placenta
sodium potassium chloride CO2
peptide bonds
lactic acidosis
15. Zinc protoporphyrin or free erythrocyte protoporphyrin measurements are useful to assess blood concentrations of...
lead
endosmosis
faster than gamma
peroxidase-like activity of hemoglobin
16. A carbonate salt used to control manic-depressive disorders is...
128
GFR
freezing point
lithium
17. Thiis serum protein fraction is most likely to be elevated in patients with nephrotic syndrome?
inhibitor binds to enzyme at same site as substrate
methadone
pCO2
alpha 2 beta
18. A common cause of respiratory alkalosis is...
hyperventilation
sharp fibrinogen peak
growth - third trimester of pregnancy
CK-MB
19. Unless blood gas measurements are made immediately after sampling - in vitro glycolysis of the blood causes a...
accuracy
parathyroid hormone
fall in pH - rise in pCO2
testing heparinized plasma
20. The most consistent analytical error involved in the routine determination of HDLcholesterol is caused by...
turn off
a small concentration of APO-B containing lipoproteins after precipitation
amylase
200
21. On immunoassays using enzyme-labeled antibodies or antigens: ___________ can be carried out with a spectrophotometer
growth - third trimester of pregnancy
elevated lactic acid - elevated pyruvate
quantitation of label
wavelength
22. Lasting serum phosphate concentration is controlled primarily by the...
glass
parathyroid
HDL
maintain colloidal osmotic pressure
23. The first step to be taken when attempting to repair a piece of electronic equipment is...
@ 100
CO2 and pH elevated
elevated lactic acid - elevated pyruvate
turn off
24. Creatinine clearance is used to estimate the...
GFR
hyperventilation
200x affinity for oxygen
correct for variations in flame and atomizer
25. A psychiatric patient was experiencing sever depression - but responded to treatment with amitriptyline with no apparent side effects. A blood sample was sent to the laboratory for therapeutic monitoring. Which drug level would be MOST reflective of
dihydroxyacetone side chain
1:5
CK
amytriptyline 104
26. Gas chromatography with the nitrogen/phosphorus detector is the most commonly used technique for the analysis of...
cyclic antidepressants
GGT
occult blood
viral hepatitis
27. The protein portion of an enzyme complex is called the...
crigler
there is an absence of correlation
apoenzyme
turn off
28. A blood gas sample was sent to the lab on ice - and a bubble was present in the syringe. The blood had been exposed to room air for at least 30 minutes. The following change in blood gases occurred...
urobilin
<45
lipase
increased O2 decreased HCO3
29. A patient is admitted to the emergency room in a state of metabolic alkalosis.This would be consistent with this diagnosis?
high co2 and hco3
without a disease with a negative test result
(testing of urine for) delta-am.. acid
90%
30. This calcium procedure utilizes lanthanum chloride to emliminate iterfering substances
porphyrin and porphobilinogen screen
atomic absorption
crigler
specimen exposure to light
31. The formula for coefficient of variation?
1 micromole per minute
SD over mean
A1
analyzed immediately
32. Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) are both elevated in this disease
CO2 and pH elevated
viral hepatitis
there is an absence of correlation
amylase and lipase
33. The fast hemoglobin fraction is...
oxalacetate to malate
A1
dirty applicators
standard
34. This is a glycolytic enzyme that catalyzes the cleavage of fructose-1 - 6-diphosphate to glyceraldehyde-3-phosphate and dihydroxyacetone phosphate
no ice clots bubbles
BUN increased
digoxin
aldolase
35. Coulometry is used to measure...
fresh morning urine for delta-aminolevulinic acid
270
chloride
volumetric flask
36. In thin layer chromatography - the Rf value for a compound is given by the...
specimen exposure to light
monitoring the course of a known cancer
effluent line is obstructed
ratio of distance moved by solvent to distance moved by compound
37. In a normal individual - injection of thyrotropin-releasing hormone (TRH) causes an increase in blood concentrations of this hormone
bilirubin
Prolactin
dirty electrodes
glycerol
38. Acidosis and alkalosis are best defined as fluctuations in blood pH and CO2 content due to changes in...
fresh morning urine for delta-aminolevulinic acid
chylomicrons
Solute moves half the distance of the solvent front
bicarbonate buffer
39. The relative migration rate of proteins on cellulose acetate is based on...
measurement of absorbance at 450
NADH
ionic charge
2Na + glucose over 20 + BUN over 3
40. Technical problems encountered during the collection of an amniotic fluid specimen caused doubt as to whether the specimen was amniotic in origin. This procedure would establish that the fluid is amniotic in origin
creatinine
act as carriers for ions
catalyze redox reactions
dirty electrodes
41. The method of choice for diagnosis of a protracted attack of porphyria is...
parathyroid
crigler
HPLC analysis of porpobilinogen on 24hr urine
tissue and serum levels need to reach equilibrium
42. Measurement of the serum acid phosphatase is used to detect neoplastic disease of the...
one micromole/minute
run a new set of controls
catalyze redox reactions
prostate
43. This chemical determination may be of help in establishing the presence of seminal fluid
wavelength
correct for variations in light intensity
acid phosphatase
ammonia
44. The biuret reaction for the analysis of serum protein depends on the number...
LDL
faster than gamma
peptide bonds
1 micromole per minute
45. A test request slip indicates that an acute porphyric attack is suspected clinically. Analysis should include...
crigler
1 micromole per minute
chloride
porphobilinigen SCREEN
46. This enzyme substrates for prostatic acid phosphatase determination results in the highest specificity
thymolpthalein monophosphate
accuracy
run a new set of controls
L/S ratio > 3.5
47. This 2-hour postprandial glucose values demonstrates unequivocal hyperglycemia diagnostic for diabetes mellitus
200
ceruplasmin
1.9
peptide bonds
48. This lipid results would be expected to be falsely elevated on a serum specimen from a nonfasting patient
quantitation of label
catalyze redox reactions
trig
band width
49. In monitoring glomerular function - this test has the highest sensitivity
creatinine clearance
chylomicrons VLDL
parathyroid hormone
dihydroxyacetone side chain
50. Sixty to seventy-five percent of the plasma cholesterol is transported by...
LDL
act as carriers for ions
coulometry
acute hepatitis