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Test your basic knowledge |
Chemistry Certification
Start Test
Study First
Subject
:
certifications
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Diagnostic specificity is defined as the percentage of individuals...
thiamine
WITHOUT a disease with a negative test
fresh morning urine for delta-aminolevulinic acid
MI
2. Major actions of angiotensin II include...
65
breast cancer
270
increased vasoconstriction
3. A patient has the following results: Patient Values : Reference Values: Serum iron 250 ug/dL 60-150 ug/dL TIBC 350 ug/dL 300-35O ug/dL The best conclusion is that this patient has...
iron hemochromatosis
MI
prevent phosphate interference
iron deficiency anemia
4. Quantitation of NA+ and K+ by ion-selective electrode is more rapid than flame photometry because...
parathyroid hormone
whole blood can be used
g/MW
testing heparinized plasma
5. In the assay of lactate dehydrogenase - this product is actually measured
NADH
LDL
prevent phosphate interference
maintain colloidal osmotic pressure
6. Beriberi is associated with deficiency of...
0
thiamine
ammonia
parathyroid
7. In performing a spinal fluid protein determination - the specimen is diluted 1 part spinal fluid to 3 parts saline to obtain a result low enough to measure. To calculate the protein concentration the result must be...
multiplied by 4
measure the total volume
SD over mean
32
8. This diseases results from a familial absence of high-density lioprotein
measure the total volume
Tangier
cyclic antidepressants
inhibitor binds to enzyme at same site as substrate
9. The chemical composition of HDL- cholesterol corresponds to...
Solute moves half the distance of the solvent front
decreased lecithin
5 tri 15 cholesterol 50 protein
occult blood
10. A patient with type I insulin-dependent diabetes mellitus has the following results: Fasting blood glucose: 150 mg/dL (70-110 rng/dL) Hemoglobin A1c: 25% (6.0%-19.5%) Fructosamine: 3.0 mmol/L ( 2.0-5.3 mmol/L)
trig
improving state of metabolic control (as indicated by fructosamine)
specificity
WITHOUT a disease with a negative test
11. Blood samples were collected at the beginning of an exercise class and after 30 minutes of aerobic activity. This would be most consistent with the postexercise sample
elevated lactic acid - elevated pyruvate
CK
incorrect aqueous to nonaqueous mixture
thyroxine
12. In competitive inhibition of an enzyme reaction the...
dihydroxyacetone side chain
inhibitor binds to enzyme at same site as substrate
no decrease in serum growth hormone after 90 minutes
prevent phosphate interference
13. In respiratory acidosis - a compensatory mechanism is the increase in...
patient noncompliance
plasma bicarbonate
LDL
acute hepatitis
14. A chemiluminescent EIA...
remove excess unbound iron
glycerol
is quantitated by the amount of light produced
volumetric flask
15. An automated CK assay gives a reading that is above the limits of linearity. A dilution of the serum sample is made by adding 1 mL of serum to 9 mL of water. The instrument now rew 350 U/L. The correct report on the undiluted serum should be...
fetal and placenta function
amylase
absorptivity x light path x concentration
3500
16. Serum from a patient with metastatic carcinoma of the prostate was separated from the clot and stored at room temperature. The following results were obtained: Patient Reference Range Calcium: 10.8 mg/dL 8.8-10.3 mg/dL LD:420 U/L 50-150 U/L Acid phos
exposure to CO
methyl alcohol
ALP with fresh draw
M subunit is inactivated
17. Four children are admitted with malaise - anorexia - and abdominal pain. Further evaluations reveal mild anemia - erythrocyte basophilic stippling - and profound pica habits. Poisoning by which heavy metal is most likely responsible?
incorrect aqueous to nonaqueous mixture
triglycerides
lead
WITHOUT a disease with a negative test
18. An emphysema patient suffering from fluid accumulation in the alveolar spaves is likely to be in what metabolic state?
fraction absorbed into systemic circulation
turn off
CML
respiratory ACIDOSIS
19. The protein portion of an enzyme complex is called the...
apoenzyme
@ 100
ceruplasmin
incorrect aqueous to nonaqueous mixture
20. Lithium therapy is widely used in the treatment of...
Wilson's disease
chylomicrons
manic-depression
LDL
21. Respiratory acidosis is described as a(n): ______ increase in CO2 decrease in pH
1:5
glucose
LDH
glycerol
22. A 45-year-old woman complains of fatigue - heat intolerance - and hair loss. Serum thyroxine and 125I-T3 resin uptake are abnormally low. What test would confirm that this is a pituitary deficiency?
B12 deficiency
measure the total volume
5 tri 15 cholesterol 50 protein
TSH
23. Zinc protoporphyrin or free erythrocyte protoporphyrin measurements are useful to assess blood concentrations of...
analyzed immediately
CO2
lead
Tay-sachs
24. The normal concentration of proteins in cerebrospinal fluid - relative to serum protein - is...
<1%
scattered at a right angle
high co2 and hco3
can be separated into distinct phenotypes
25. In spectrophotometric determination - this is the formula for calculating the absorbance of a solution
carbohydrate hyperalimentation
absorptivity x light path x concentration
21-hydroxylase deficiency
cmpds based on molecular weight and size
26. A patient in her 33rd week of pregnancy is hospitalized with toxemia. Her doctor would like to deliver the baby early because the toxemia is becoming more severe. The baby's best chance of delivery without respiratory distress due to lung immaturity
L/S ratio > 3.5
chloride
respiratory ACIDOSIS
without a disease with a negative test result
27. The osmolality of a urine or serum specimen is measured by a change in the...
C3 complement
freezing point
primidone
standard
28. In electrophoretic analysis - buffers...
act as carriers for ions
amylase and lipase
scattered at a right angle
alpha 2 beta
29. Rickets is associated with deficiency of...
glass
D
100nmol
growth - third trimester of pregnancy
30. An acid cleaning solution for glassware consists of...
potassium dichromate in SA
urobilin
correct for variations in light intensity
GFR
31. Pregnant women with symptoms of thirst - frequent urination - or unexplained weight loss should have this test performed?
chylomicrons VLDL
glucose tolerance test
F
prevent phosphate interference
32. In an internal standard flame photometer - the internal standard is used to...
there is an absence of correlation
correct for variations in flame and atomizer
attaching them to protein molecules
measurement of absorbance at 450
33. When myocardial infarction occurs - the first enzyme to become elevated is...
transferrin
iron deficiency anemia
draw blood for glucose and discontinue test
CK
34. Most drugs and intracellular metabolites measured by radioimmunoassay have molecular weights between 200 and 1000 and can be made immunogenic by...
no decrease in serum growth hormone after 90 minutes
attaching them to protein molecules
Wilson's disease
prisms and grating
35. Which two conditions can "physiologically" elevate serum alkaline phosphatase?
volumetric flask
measure the total volume
growth - third trimester of pregnancy
C
36. Assay of transketolase activity in blood is used to detect deficiency of...
serum aliquots - one heated
thiamine
C
chemical ionization matrix
37. A 25-year-old man became nauseated and vomited 90 minutes after receiving a standard 75-g carbohydrate dose for an oral glucose tolerance test. The best course of action is...
BUN 80
cyclic antidepressants
measurement of absorbance at 450
draw blood for glucose and discontinue test
38. Most most likely to be ordered in addition to serum calcium to determine the cause of tetany?
Mg
amytriptyline 104
trig
measure the total volume
39. A common cause of a falsely increased LD1 fraction of lactic dehydrogenase is...
100nmol
minimize the effects of interference
591
hemolysis
40. The following data were obtained from a cellulose acetate protein electrophoresis scan: Albumin area 75 units Gamma globulin area 30 units Total area 180 units Total protein 6.5 g/dL The gamma globulin content in g/dL is...
thyroxine binding globulin
5mg higher
digoxin
1.1
41. A patient with hemolytic anemia will...
@ 100
glucose tolerance test
TSH
show a decrease in glycosylated hgb
42. The principle of the occult blood test depends on the...
attaching them to protein molecules
increased O2 decreased HCO3
peroxidase-like activity of hemoglobin
LDL
43. If a drug has a half-life of 7 hours - how many doses given at 7-hour intervals does it usually take to achieve a steady state or plateau level?
5
ionic charge
T4 by RIA
be able to detect 9/10 simple instrument malfunctions
44. One international unit of enzyme activity is the amount of enzyme that - under specified reaction conditions of substrate concentration - pH - and temperature - causes utilization of substrate at the rate of...
WITHOUT a disease with a negative test
1 micromole per minute
Solute moves half the distance of the solvent front
carbs
45. This serum protein migrates with the beta-globulins on cellulose acetate at pH 8.6...
C3 complement
5mg higher
Hb S
endogenous triglycerides
46. Bioavailability of a drug refers to the...
serum cortisol > 15
fraction absorbed into systemic circulation
cysteine
the same as plasma glucose
47. Cocaine is metabolized to...
carbohydrate hyperalimentation
340
benzoylecogine
specificity
48. Fluctuation of the needle on a coulometric type titrator is most probably due to...
dirty electrodes
digoxin
sodium potassium chloride CO2
glucose tolerance test
49. In the sweat test - the sweating stimulant is introduced to the skin by application of...
5mg higher
electric current
specimen exposure to light
100 nmol
50. Upon development of a thin layer chromatogram for the drug analysis - all drug spots (including the standards) had migrated with the solvent front. The most probable cause for this would be...
incorrect aqueous to nonaqueous mixture
Solute moves half the distance of the solvent front
2-log(T)
5