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Test your basic knowledge |
Chemistry Certification
Start Test
Study First
Subject
:
certifications
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. A patient with type I insulin-dependent diabetes mellitus has the following results: Fasting blood glucose: 150 mg/dL (70-110 rng/dL) Hemoglobin A1c: 25% (6.0%-19.5%) Fructosamine: 3.0 mmol/L ( 2.0-5.3 mmol/L)
improving state of metabolic control (as indicated by fructosamine)
exposure to CO
(testing of urine for) delta-am.. acid
freezing point
2. Gas chromatography with the nitrogen/phosphorus detector is the most commonly used technique for the analysis of...
cyclic antidepressants
F
ionic charge
9
3. Stray light can be detected in a spectrophotometer by utilizing a...
analyzed immediately
prevent phosphate interference
sharp cutoff filter
4.5
4. When the exact concentration of the solute of a solution is known and is used to evaluate the concentration of an unknown solution - the known solution is...
peroxidase-like activity of hemoglobin
Tay-sachs
cyclic antidepressants
standard
5. Most most likely to be ordered in addition to serum calcium to determine the cause of tetany?
hyperthyroidism
Mg
is quantitated by the amount of light produced
apoenzyme
6. The normal concentration of proteins in cerebrospinal fluid - relative to serum protein - is...
dirty electrodes
endogenous triglycerides
<1%
2Na + glucose over 20 + BUN over 3
7. Most chemical methods for determining total protein utilize this reaction?
biuret
bilirubindiglucuronide
A1
200x affinity for oxygen
8. The expected blood gas results for a patient in chronic renal failure would match the pattern of...
faster than gamma
acid phosphatase
metabolic acidosis
high co2 and hco3
9. The main reason for suboptimal drug levels in therapeutic drug monitoring is...
changes in the fuel
patient noncompliance
T4 by RIA
fetal and placenta function
10. The identification of Bence Jones protein is best accomplished by...
immunofixation
@ 100
incorrect aqueous to nonaqueous mixture
specimen exposure to light
11. Following overnight fasting - hypoglycemia in adults is defined as a glucose of...
Hb S
prostate
5 tri 15 cholesterol 50 protein
<45
12. In familial hypercholesterolemia - the hallmark finding is an elevation of...
no ice clots bubbles
obstructive jaundice
LDL
para-hydroxylphenyl...
13. Maple syrup urine disease is characterized by an increase in this urinary amino acids
is quantitated by the amount of light produced
breast cancer
valine leucine isoleucine
glucose
14. Amino acid associated with a sulfhydryl group
prisms and grating
WITHOUT a disease with a negative test
cysteine
sample exposed to light
15. A common cause of respiratory alkalosis is...
increase in total circulating T4
hyperventilation
0
be able to detect 9/10 simple instrument malfunctions
16. In respiratory acidosis - a compensatory mechanism is the increase in...
alpha 2 beta
fresh morning urine for delta-aminolevulinic acid
intestinal malabsorption
plasma bicarbonate
17. The selectivity of an ion-selective electrode is determined by the...
F
increased O2 decreased HCO3
properties of the membrane
pO2 increased HCO3 decreased
18. The osmolal gap is defined as measured Osm/kg minus the calculated Osm/kg. The average osmolal gap is near...
minimize the effects of interference
measures one ion more than others
sharp fibrinogen peak
0
19. A patient had the following serum results: Na+ 140 mEq/L K+ 4.0 mEq/L Glucose 95 mg/dL BUN 10 mg/dL Which osmolality is consistent with these results?
acute intermittent porphyria
minimize the effects of interference
Temperature is a function of the number of particles in solution
270
20. Serum haptoglobin...
monitoring the course of a known cancer
sodium
can be separated into distinct phenotypes
sharp fibrinogen peak
21. Technical problems encountered during the collection of an amniotic fluid specimen caused doubt as to whether the specimen was amniotic in origin. This procedure would establish that the fluid is amniotic in origin
parathyroid hormone
creatinine
1:5
chloride
22. Currently the most common method for specific identification and quantitation of serum barbiturates is...
SD over mean
GLC
fetal and placenta function
g/MW
23. In using ion-exchange chromatographicbmethods - falsely increased levels of Hgb A1c will be demonstrated in presence of...
chylomicrons
Hb S
iron deficiency anemia
increased vasoconstriction
24. How many grams of sodium chloride are needed to prepare 1 L of 0.9% normal saline?
binding capacity of thyroxine-binding globulin
chylomicrons
para-hydroxylphenyl...
9
25. The principle of the occult blood test depends on the...
peroxidase-like activity of hemoglobin
peptide bonds
CML
electric current
26. Cocaine is metabolized to...
benzoylecogine
hyperthyroidism
TSH
primary hyperparathyroidism
27. The general types of interference in atomic absorption spectrophotometry...
band width
nondiagnostic for MS
chemical ionization matrix
glucose tolerance test
28. Serum anion gap is increased in patients with...
cholesterol normal triglycerides elevated
lactic acidosis
remove excess unbound iron
purulent
29. The biologically most active - naturally occuring androgen is...
beta
testosterone
pH = pKa + log (salt/acid)
inhibitor binds to enzyme at same site as substrate
30. What substance gives feces its normal color?
creatine kinase
pO2 increased HCO3 decreased
iron deficiency anemia
urobilin
31. This enzyme substrates for prostatic acid phosphatase determination results in the highest specificity
thyroxine binding globulin
thymolpthalein monophosphate
F
specificity
32. Kernicterus is an abnormal accumulation of bilirubin in...
freezing point
volumetric flask
placenta
brain
33. Calcium concentration in the serum is regulated by...
CK
parathyroid hormone
pituitary
be able to detect 9/10 simple instrument malfunctions
34. The most consistent analytical error involved in the routine determination of HDLcholesterol is caused by...
atomic absorption
a small concentration of APO-B containing lipoproteins after precipitation
5 tri 15 cholesterol 50 protein
changes in the fuel
35. This serum protein migrates with the beta-globulins on cellulose acetate at pH 8.6...
MI
C3 complement
adding an acid stabilizer
F
36. The following data were obtained from a cellulose acetate protein electrophoresis scan: Albumin area 75 units Gamma globulin area 30 units Total area 180 units Total protein 6.5 g/dL The gamma globulin content in g/dL is...
nondiagnostic for MS
Mg
acute intermittent porphyria
1.1
37. A potentiometric electrode that measures an analyte that passes through a selectively premeable membrane and rapidly enters into an equilibrium with an electrolyte solution is...
pCO2
thiamine
5 tri 15 cholesterol 50 protein
fresh morning urine for delta-aminolevulinic acid
38. A patient is admitted with biliary cirrhosis. If a serum protein electrophoresis is preformed - these globulin fractions will be most elevated?
inhibitor binds to enzyme at same site as substrate
obstructive jaundice
beta
LDL
39. This hemoglobin has glucose-6-phosphate on the amino-terminal valine of the beta chain?
2Na + glucose over 20 + BUN over 3
A1c
65
spun separated iced and tested immediately
40. Serum concentrations of vitamin B12 are elevated in...
iron deficiency anemia
CML
200
pCO2
41. The serum glucose concentration of a diabetic patient undergoing a 2-hour glucose tolerance test should return to the baseline (fasting level) after a minimum of...
acute intermittent porphyria
HDL
120 minutes
hyperthyroidism
42. A new method is being evaluated. A recovery experiment is performed with the following results: 0.9 mL serum sample + 0.1 mL H20 = 89 mEq/L 0.9 mL serum sample + 0.1 mL analyte std. @ 800 mEq/L = 161 mEq/L The percent recovery of the added analyt
parathyroid
90%
catalyze redox reactions
specimen exposure to light
43. The anticonvulsant used to control tonic-clonic (grand mal) seizures is...
A1c
phenytoin
pilocarpine
chemical ionization matrix
44. The following laboratory results were obtained on arterial blood: Sodium 136 mEq/L pH 7.32 Potassium 4.4 mEq/L PCO2 79 mm Hg Chloride 92 mEq/L Bicarbonate 40 mEq/L These results are most compatible with...
nephelometry
agarose
respiratory acidosis
ammonia
45. Diagnostic specificity is defined as the percentage of individuals...
wavelength
increased vasoconstriction
without a disease with a negative test result
HDL
46. The function of the major lipid components of the very low density lipoproteins (VLDL) is to transport...
prisms and grating
apoenzyme
placenta
endogenous triglycerides
47. A 9-month-old boy from Israel has gradually lost the ability to sit up and develops seizures. He has an increased amount of a phospholipid called GM2-ganglioside in his neurons - and he lacks the enzyme hexosaminidase A in his leukocytes. These findi
increase in total circulating T4
Tay-sachs
quantitation of label
crigler
48. Creatinine clearance is used to estimate the...
GFR
run a new set of controls
100nmol
(testing of urine for) delta-am.. acid
49. One international unit of enzyme activity is the amount of enzyme that - under specified reaction conditions of substrate concentration - pH - and temperature - causes utilization of substrate at the rate of...
1 micromole per minute
prevent phosphate interference
glucose
sample exposed to light
50. The direction in which albumin migrates (ie - toward anode or cathode) during electrophoretic separation of serum proteins - at pH 8.6 - is determined by...
faster than gamma
occult blood
pCO2
ionization of carboxyl groups (yielding a net negative charge)