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Test your basic knowledge |
Chemistry Certification
Start Test
Study First
Subject
:
certifications
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. In the immunoinhibition phase of the CK-MB procedure...
M subunit is inactivated
glycerol
CO2
heparin
2. The measurement of light scattered by particles in the sample is the principle of...
9
D
nephelometry
340
3. In electrophoresis of serum proteins - arifacts at the application point are most frequently caused by...
pH = pKa + log (salt/acid)
turn off
show a decrease in glycosylated hgb
dirty applicators
4. The selectivity of an ion-selective electrode is determined by the...
properties of the membrane
manic-depression
parathyroid hormone
adding an acid stabilizer
5. On immunoassays using enzyme-labeled antibodies or antigens: ___________ can be carried out with a spectrophotometer
WITHOUT a disease with a negative test
emphysema
pCO2
quantitation of label
6. Nephelometers measure light...
SD over mean
scattered at a right angle
testing heparinized plasma
CO2
7. An automated CK assay gives a reading that is above the limits of linearity. A dilution of the serum sample is made by adding 1 mL of serum to 9 mL of water. The instrument now rew 350 U/L. The correct report on the undiluted serum should be...
3500
impaired response to ACTH stimulation
carbohydrate hyperalimentation
@ 100
8. A patient in her 33rd week of pregnancy is hospitalized with toxemia. Her doctor would like to deliver the baby early because the toxemia is becoming more severe. The baby's best chance of delivery without respiratory distress due to lung immaturity
L/S ratio > 3.5
pituitary
nondiagnostic for MS
120 minutes
9. A patient had the following serum results: Na+ 140 mEq/L K+ 4.0 mEq/L Glucose 95 mg/dL BUN 10 mg/dL Which osmolality is consistent with these results?
F
270
C
chemical ionization matrix
10. The test for adrenal cortical hyperfunction that has the greatest diagnostic sensitivity is measurement of...
the same as plasma glucose
breast cancer
urinary free cortisol
inclusion of smokers and nonsmokers in the study population
11. The osmolality of a urine or serum specimen is measured by a change in the...
GGT
freezing point
lead
fresh morning urine for delta-aminolevulinic acid
12. An automated method for measuring chloride that generates silver ions in the reaction is...
impaired response to ACTH stimulation
coulometry
emphysema
para-hydroxylphenyl...
13. Bioavailability of a drug refers to the...
fraction absorbed into systemic circulation
1 micromole per minute
draw blood for glucose and discontinue test
GFR
14. A serum sample for acid phosphatase determination is best prepared for room temperature storage by...
remove excess unbound iron
1.1
adding an acid stabilizer
Hb S
15. To ensure an accurate ammonia level result - the specimen should be...
CML
chylomicrons
spun separated iced and tested immediately
parathyroid
16. A 9-month-old boy from Israel has gradually lost the ability to sit up and develops seizures. He has an increased amount of a phospholipid called GM2-ganglioside in his neurons - and he lacks the enzyme hexosaminidase A in his leukocytes. These findi
placenta
Tay-sachs
acid phosphatase
bone
17. This 2-hour postprandial glucose values demonstrates unequivocal hyperglycemia diagnostic for diabetes mellitus
alpha 2 beta
CO2 and pH elevated
200
digoxin
18. Characteristic of the Bence Jones protein that is used to distinguish it from other urinary proteins is its solubility...
endosmosis
occult blood
@ 100
urobilin
19. A one MOLAL solution is equivalent to...
sodium
1 mol/kg
mg/ml
low pH
20. The most important buffer pair in plasma is the...
chloride
NADH
bicarbonate carbonic acid
conjugated hyperbilirubinemia - hepatocellular obstruction
21. Analysis of erythrocytes for uroporphyrinogen I synthetase detects...
acute intermittent porphyria
glass
inclusion of smokers and nonsmokers in the study population
sharp fibrinogen peak
22. In competitive inhibition of an enzyme reaction the...
hyperthyroidism
NADH
check serum for hemolysis
inhibitor binds to enzyme at same site as substrate
23. A test request slip indicates that an acute porphyric attack is suspected clinically. Analysis should include...
impaired response to ACTH stimulation
TSH
porphobilinogen screen
changes in the fuel
24. The following laboratory results were obtained: Serum Calcium: Increased - Urine Calcium: Increased - Serum Phosphate: Decreased - Urine Phosphate: Increased Serum Alkaline Phosphatase: Normal or Increased These results are most compatible with...
the fetus is at risk for respiratory distress
specificity
100 nmol
primary hyperparathyroidism
25. Most drugs and intracellular metabolites measured by radioimmunoassay have molecular weights between 200 and 1000 and can be made immunogenic by...
attaching them to protein molecules
lower than in adults
intestinal malabsorption
lead
26. The following data were obtained from a cellulose acetate protein electrophoresis scan: Albumin area 75 units Gamma globulin area 30 units Total area 180 units Total protein 6.5 g/dL The gamma globulin content in g/dL is...
bilirubindiglucuronide
dirty applicators
1.1
correct for variations in light intensity
27. A patient with malabsorption receives 25 g of d-xylose orally; during the subsequent 5-hour period - the urine excretion of d-xylose is less than 3 g. This would indicate...
bilirubindiglucuronide
intestinal malabsorption
faster than gamma
the fetus is at risk for respiratory distress
28. Gel filtration chromatography is used to separate...
20:1
CO2
cmpds based on molecular weight and size
parathyroid
29. An electrode has a silver/silver chloride anode and a platinum wire cathode. It is suspended in KCl solution and separated from the blood to be analyzed by a selectively permeable membrane. Such an electrode is used to measure...
can be separated into distinct phenotypes
sharp cutoff filter
O2
5 tri 15 cholesterol 50 protein
30. In monitoring glomerular function - this test has the highest sensitivity
methyl alcohol
porphyrin and porphobilinogen screen
oxalacetate to malate
creatinine clearance
31. At a pH of 8.6 the gamma globulins move toward the cathode - despite the fact that they are negatively charged. What is this phenomenon called?
have a negative charge
pH = pKa + log (salt/acid)
endosmosis
testosterone
32. These enzymes of heme biosynthesis are inhibited by lead
porphobilinogen synthetase
sodium
lipase
primary hyperparathyroidism
33. The serum glucose concentration of a diabetic patient undergoing a 2-hour glucose tolerance test should return to the baseline (fasting level) after a minimum of...
1 mol/kg
maintain colloidal osmotic pressure
bone
120 minutes
34. At blood pH 7.40 what is the ratio between bicarbonate and carbonic acid?
20:1
digoxin
atomic absorption
bilirubin
35. This hemoglobin has glucose-6-phosphate on the amino-terminal valine of the beta chain?
wavelength
LDH
glucose oxidase
A1c
36. The anion gap is useful for quality control of laboratory results for...
sodium potassium chloride CO2
ammonia
cmpds based on molecular weight and size
urinary free cortisol
37. In spectrophotometric determination - this is the formula for calculating the absorbance of a solution
run a new set of controls
absorptivity x light path x concentration
binding capacity of thyroxine-binding globulin
agarose
38. A blood sample was received from the emergency room with a request for narcotic analysis. The request slip indicated that the patient (a known heroin addict) responded to naloxone administration. The serum was negative for morphine by EIA. What other
cmpds based on molecular weight and size
faster than gamma
methadone
creatinine clearance
39. The fast hemoglobin fraction is...
A1
HDL
lead
<1%
40. A carbonate salt used to control manic-depressive disorders is...
chylomicrons
serum aliquots - one heated
lithium
low pH
41. A patient has the following results: Patient Values : Reference Values: Serum iron 250 ug/dL 60-150 ug/dL TIBC 350 ug/dL 300-35O ug/dL The best conclusion is that this patient has...
iron hemochromatosis
effluent line is obstructed
emphysema
O2
42. A spectrophotometer is being considered for purchase by a small laboratory. This specification reflects the spectral purity of the instrument
band width
correct for variations in flame and atomizer
plasma bicarbonate
ammonia
43. A patient with type I insulin-dependent diabetes mellitus has the following results: Fasting blood glucose: 150 mg/dL (70-110 rng/dL) Hemoglobin A1c: 25% (6.0%-19.5%) Fructosamine: 3.0 mmol/L ( 2.0-5.3 mmol/L)
improving state of metabolic control (as indicated by fructosamine)
analyzed immediately
Prolactin
65
44. A breakdown product of hemoglobin is...
sharp fibrinogen peak
sample exposed to light
2Na + glucose over 20 + BUN over 3
bilirubin
45. When taken by a euthyroid individual - oral contraceptives containing estrogens will have this effects on the thyroid function studies
acid phosphatase
brain
increase in total circulating T4
32
46. A pH of 7.0 represents a H+ concentration of...
100 nmol
iron deficiency anemia
endogenous triglycerides
GLC
47. The method of choice for diagnosis of a protracted attack of porphyria is...
respiratory acidosis
HPLC analysis of porpobilinogen on 24hr urine
increased vasoconstriction
pituitary
48. In the Jaffe reaction - creatine reacts with...
respiratory ACIDOSIS
parathyroid hormone
bicarbonate carbonic acid
alkaline picrate
49. Magnesium carbonate is added in an iron binding capacity determination in order to...
9
can be separated into distinct phenotypes
remove excess unbound iron
thyroxine binding globulin
50. The most common type of congenital adrenal hyperplasia associated with increased plasma concentrations of 17 a-hydroxyprogesterone and increased urinary excretion of pregnanetriol is...
21-hydroxylase deficiency
specificity
increased O2 decreased HCO3
whole blood can be used