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Test your basic knowledge |
Chemistry Certification
Start Test
Study First
Subject
:
certifications
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. The stimulant that causes localized sweating for the sweat test is...
100 nmol
spun separated iced and tested immediately
high co2 and hco3
pilocarpine
2. Which percentage of total serum calcium is nondiffusible protein bound?
40-50
CO2
heparin
1 micromole per minute
3. This electrolyte is the chief plasma cation whose main function is maintaining osmotic pressure
porphobilinogen screen
1:5
sodium
200
4. Turbidity in serum suggests elevation of...
chylomicrons
Hb S
dirty electrodes
emphysema
5. In the assay of lactate dehydrogenase - this product is actually measured
dirty applicators
NADH
can be used for absorbtion - partition - ion exchange - and gel permeation chromatography
B12 deficiency
6. Unless blood gas measurements are made immediately after sampling - in vitro glycolysis of the blood causes a...
90%
benzoylecogine
fall in pH - rise in pCO2
crigler
7. High levels of which lipoprotein class are associated with decreased risk of accelerated atherosclerosis?
porphyrin and porphobilinogen screen
dirty applicators
HDL
run a new set of controls
8. When myocardial infarction occurs - the first enzyme to become elevated is...
creatine kinase
CK
CO2
measure the total volume
9. An automated CK assay gives a reading that is above the limits of linearity. A dilution of the serum sample is made by adding 1 mL of serum to 9 mL of water. The instrument now rew 350 U/L. The correct report on the undiluted serum should be...
3500
elevated lactic acid - elevated pyruvate
no decrease in serum growth hormone after 90 minutes
glucose
10. A stool specimen that appears black and tarry should be tested for the presence of...
adding an acid stabilizer
occult blood
bilirubindiglucuronide
increased vasoconstriction
11. An automated method for measuring chloride that generates silver ions in the reaction is...
brain
alpha 2 beta
diet
coulometry
12. Aminotransferase enzymes catalyze the...
emphysema
GFR
serum aliquots - one heated
exchange of amino and keto groups
13. In the atomic absorption method for calcium - lanthanum is used...
HPLC analysis of porpobilinogen on 24hr urine
MI
prevent phosphate interference
respiratory ACIDOSIS
14. The selectivity of an ion-selective electrode is determined by the...
dihydroxyacetone side chain
hepatobiliary (obstruction?)
properties of the membrane
maintain colloidal osmotic pressure
15. Zinc protoporphyrin or free erythrocyte protoporphyrin measurements are useful to assess blood concentrations of...
lead
primidone
0
thiamine
16. Most drugs and intracellular metabolites measured by radioimmunoassay have molecular weights between 200 and 1000 and can be made immunogenic by...
glass
attaching them to protein molecules
Wilson's disease
5mg higher
17. A pH of 7.0 represents a H+ concentration of...
100 nmol
aldolase
occult blood
HPLC analysis of porpobilinogen on 24hr urine
18. The following data were obtained from a cellulose acetate protein electrophoresis scan: Albumin area 75 units Gamma globulin area 30 units Total area 180 units Total protein 6.5 g/dL The gamma globulin content in g/dL is...
1.1
inclusion of smokers and nonsmokers in the study population
B12 deficiency
ammonia
19. This elevates carboxyhemoglobin?
exposure to CO
CK
triglycerides
hyperthyroidism
20. In performing a spinal fluid protein determination - the specimen is diluted 1 part spinal fluid to 3 parts saline to obtain a result low enough to measure. To calculate the protein concentration the result must be...
parathyroid
phenytoin
multiplied by 4
TSH
21. The osmolality of a urine or serum specimen is measured by a change in the...
freezing point
sodium
parathyroid hormone
increased O2 decreased HCO3
22. While performing a serum lithium determination on a flame photometer with cesium as the internal standard - the technologist noticed that there was a flickering flame. The most probable cause of this problem is...
valine leucine isoleucine
glucose tolerance test
changes in the fuel
BUN 80
23. The buffer pH most effective at allowing amphoteric proteins to migrate toward the cathode in an electrophoretic system would be...
the same as plasma glucose
4.5
elevated lactic acid - elevated pyruvate
glucose oxidase
24. The electrophoretic pattern of a plasma sample compared with a serum sample shows a...
absorptivity x light path x concentration
120 minutes
TLC
sharp fibrinogen peak
25. The anticonvulsant used to control tonic-clonic (grand mal) seizures is...
band width
340
ALP with fresh draw
phenytoin
26. Respiratory acidosis is described as a(n): ______ increase in CO2 decrease in pH
nondiagnostic for MS
obstructive jaundice
glycerol
lead
27. In the immunoinhibition phase of the CK-MB procedure...
M subunit is inactivated
pCO2
digoxin
thiamine
28. In developing the reference for a new EIA for CEA - the range for the normal population was broader than that published by the vendor. Controls are acceptable with a narrow coefficient of variation. This may be explained by...
inclusion of smokers and nonsmokers in the study population
amylase and lipase
changes in the fuel
Temperature is a function of the number of particles in solution
29. The enzyme present in almost all tissues that may be separated by electrophoresis into five components is...
LDL
LDH
intestinal malabsorption
normal - liver breakdown
30. A 9-month-old boy from Israel has gradually lost the ability to sit up and develops seizures. He has an increased amount of a phospholipid called GM2-ganglioside in his neurons - and he lacks the enzyme hexosaminidase A in his leukocytes. These findi
specificity
CO2
intestinal malabsorption
Tay-sachs
31. Total iron-binding capacity measures the serum iron transporting capacity of...
transferrin
can be used for absorbtion - partition - ion exchange - and gel permeation chromatography
primidone
beta
32. Technical problems encountered during the collection of an amniotic fluid specimen caused doubt as to whether the specimen was amniotic in origin. This procedure would establish that the fluid is amniotic in origin
testing heparinized plasma
oxalacetate to malate
creatinine
can be separated into distinct phenotypes
33. Lithium therapy is widely used in the treatment of...
iron hemochromatosis
9
correct for variations in flame and atomizer
manic-depression
34. The normal concentration of proteins in cerebrospinal fluid - relative to serum protein - is...
<1%
ionic charge
minimize the effects of interference
M subunit is inactivated
35. These enzymes of heme biosynthesis are inhibited by lead
porphobilinogen synthetase
TLC
thiamine
heparin
36. The following results were obtained in a creatinine clearance evaluation: Urine concentration 84 mg/dL Urine volume 1440 mL/24 hr Serum concentration 1.4 mg/dL Body surface area 1.60 m2 (average = 1.73 m2) The creatinine cle~trance in mL/min is...
peptide bonds
monitoring the course of a known cancer
effluent line is obstructed
65
37. A blood gas sample was sent to the lab on ice - and a bubble was present in the syringe. The blood had been exposed to room air for at least 30 minutes. The following change in blood gases occurred...
pituitary
increased O2 decreased HCO3
metabolic acidosis
inclusion of smokers and nonsmokers in the study population
38. The most consistent analytical error involved in the routine determination of HDLcholesterol is caused by...
check serum for hemolysis
run a new set of controls
a small concentration of APO-B containing lipoproteins after precipitation
L/S ratio > 3.5
39. To ensure an accurate ammonia level result - the specimen should be...
20:1
occult blood
no ice clots bubbles
spun separated iced and tested immediately
40. The buffering capacity of blood is maintained by a reversible exchange process between bicarbonate and...
manic-depression
tissue and serum levels need to reach equilibrium
chloride
decreased lecithin
41. Quantitation of NA+ and K+ by ion-selective electrode is more rapid than flame photometry because...
M subunit is inactivated
dihydroxyacetone side chain
200
whole blood can be used
42. A potentiometric electrode that measures an analyte that passes through a selectively premeable membrane and rapidly enters into an equilibrium with an electrolyte solution is...
improving state of metabolic control (as indicated by fructosamine)
crigler
M subunit is inactivated
pCO2
43. One international unit of enzyme activity is the amount of enzyme that - under specified reaction conditions of substrate concentration - pH - and temperature - causes utilization of substrate at the rate of...
changes in the fuel
porphobilinogen synthetase
1 micromole per minute
occult blood
44. Upon development of a thin layer chromatogram for the drug analysis - all drug spots (including the standards) had migrated with the solvent front. The most probable cause for this would be...
32
incorrect aqueous to nonaqueous mixture
elevated lactic acid - elevated pyruvate
catalyze redox reactions
45. The most widely employed screening technique for drug abuse is...
pO2 increased HCO3 decreased
591
effluent line is obstructed
TLC
46. Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) are both elevated in this disease
viral hepatitis
iron deficiency anemia
chemical ionization matrix
pH = pKa + log (salt/acid)
47. A 45-year-old woman has a fasting serum glucose concentration of 95 mg/dL and a 2-hour postprandial glucose concentration of 105 mg/dL. The statement that best describes this patient's fasting serum glucose concentration is...
one micromole/minute
normal - liver breakdown
1.1
remove excess unbound iron
48. A patient had the following serum results: Na+ 140 mEq/L K+ 4.0 mEq/L Glucose 95 mg/dL BUN 10 mg/dL Which osmolality is consistent with these results?
correct for variations in flame and atomizer
270
T4 by RIA
changes in the fuel
49. In spectrophotometric determination - this is the formula for calculating the absorbance of a solution
90%
absorptivity x light path x concentration
hepatobiliary (obstruction?)
100nmol
50. Rickets is associated with deficiency of...
a small concentration of APO-B containing lipoproteins after precipitation
pH pCO2 pO2
5 tri 15 cholesterol 50 protein
D