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Test your basic knowledge |
Chemistry Certification
Start Test
Study First
Subject
:
certifications
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Creatinine clearance is used to estimate the...
GFR
(testing of urine for) delta-am.. acid
sharp fibrinogen peak
fall in pH - rise in pCO2
2. Testing for the diagnosis of lead poisoning should include...
(testing of urine for) delta-am.. acid
occult blood
obstructive jaundice
lipase
3. Calcium concentration in the serum is regulated by...
parathyroid hormone
sodium potassium chloride CO2
ionic charge
enzyme immunoassay
4. The fast hemoglobin fraction is...
A1
manic-depression
viral hepatitis
increased O2 decreased HCO3
5. Total iron-binding capacity measures the serum iron transporting capacity of...
transferrin
5
<1%
biuret
6. The function of the major lipid components of the very low density lipoproteins (VLDL) is to transport...
9
inclusion of smokers and nonsmokers in the study population
HDL
endogenous triglycerides
7. The concentration of serum carotene is affected MOST by...
diet
Tangier
bone
BUN increased
8. This elevates carboxyhemoglobin?
viral hepatitis
B12 deficiency
GLC
exposure to CO
9. A test request slip indicates that an acute porphyric attack is suspected clinically. Analysis should include...
be able to detect 9/10 simple instrument malfunctions
MI
HDL
porphobilinigen SCREEN
10. This condition does decrease activity of glucuronyl transferase result in increased unconjugated bilirubin and kernicterus in neonates
crigler
there is an absence of correlation
no ice clots bubbles
remove excess unbound iron
11. An electrophoretic separation of lactate dehydrogenase isoenzymes that demonstrates an elevation in LD-l and LD-2 in a "flipped" pattern is consistent with...
MI
coulometry
glycerol
show a decrease in glycosylated hgb
12. Most drugs and intracellular metabolites measured by radioimmunoassay have molecular weights between 200 and 1000 and can be made immunogenic by...
attaching them to protein molecules
porphobilinogen screen
monitoring the course of a known cancer
L/S ratio > 3.5
13. The serum glucose concentration of a diabetic patient undergoing a 2-hour glucose tolerance test should return to the baseline (fasting level) after a minimum of...
F
120 minutes
turn off
9
14. The formation of estriol in a pregnant woman is dependent on...
fall in pH - rise in pCO2
fraction absorbed into systemic circulation
acute hepatitis
fetal and placenta function
15. Characteristic of the Bence Jones protein that is used to distinguish it from other urinary proteins is its solubility...
@ 100
iron hemochromatosis
obstructive jaundice
decreased lecithin
16. The Henderson-Hasselbalch equation
thyroxine
pH = pKa + log (salt/acid)
CO2
enzyme induction
17. In using ion-exchange chromatographicbmethods - falsely increased levels of Hgb A1c will be demonstrated in presence of...
CO2
5 tri 15 cholesterol 50 protein
valine leucine isoleucine
Hb S
18. Rickets is associated with deficiency of...
D
glucose oxidase
3500
B12 deficiency
19. A one MOLAL solution is equivalent to...
phenytoin
can be used for absorbtion - partition - ion exchange - and gel permeation chromatography
A1
1 mol/kg
20. This would be an example of a glucose-specific colorimetric method
sharp fibrinogen peak
fresh morning urine for delta-aminolevulinic acid
iron deficiency anemia
glucose oxidase
21. In a normal individual - injection of thyrotropin-releasing hormone (TRH) causes an increase in blood concentrations of this hormone
Prolactin
chylomicrons
Solute moves half the distance of the solvent front
maintain colloidal osmotic pressure
22. The electrophoretic pattern of a plasma sample compared with a serum sample shows a...
increased vasoconstriction
sharp fibrinogen peak
there is an absence of correlation
respiratory acidosis
23. The direction in which albumin migrates (ie - toward anode or cathode) during electrophoretic separation of serum proteins - at pH 8.6 - is determined by...
ionization of carboxyl groups (yielding a net negative charge)
4.5
volumetric flask
LDL
24. A blood sample was received from the emergency room with a request for narcotic analysis. The request slip indicated that the patient (a known heroin addict) responded to naloxone administration. The serum was negative for morphine by EIA. What other
methadone
properties of the membrane
A1
Calcium - phosphorus
25. This method employs a highly specific antibody to thyroxine
show a decrease in glycosylated hgb
@ 100
lithium
T4 by RIA
26. The following data were obtained from a cellulose acetate protein electrophoresis scan: Albumin area 75 units Gamma globulin area 30 units Total area 180 units Total protein 6.5 g/dL The gamma globulin content in g/dL is...
electric current
1.1
ammonia
conjugated hyperbilirubinemia - hepatocellular obstruction
27. A technician is asked by the supervisor to prepare a standard solution from the stock standard. What is the glassware of choice for this solution?
accuracy
nondiagnostic for MS
Solute moves half the distance of the solvent front
volumetric flask
28. The nanometer is a measurement of...
analyzed immediately
nephelometry
normal - liver breakdown
wavelength
29. Blood samples were collected at the beginning of an exercise class and after 30 minutes of aerobic activity. This would be most consistent with the postexercise sample
run a new set of controls
CK
elevated lactic acid - elevated pyruvate
1.9
30. The reason carbon monoxide is so toxic is because it...
maintain colloidal osmotic pressure
pCO2
200x affinity for oxygen
porphobilinogen synthetase
31. This electrolyte is the chief plasma cation whose main function is maintaining osmotic pressure
sodium
properties of the membrane
no ice clots bubbles
primary hyperparathyroidism
32. A 21-year-old man with nausea - vomiting - and jaundice has the following laboratory findings: Total serum bilirubin level: 8.5 mg/dL (normal - 0-1.0) Conjugated serum bilirubin level: 6.1 mg/dL (normal - 0-0.5) Urine urobilinogen: Increased Fecal u
trig
apoenzyme
nephelometry
conjugated hyperbilirubinemia - hepatocellular obstruction
33. Beriberi is associated with deficiency of...
tissue and serum levels need to reach equilibrium
parathyroid
analyzed immediately
thiamine
34. The biuret reaction for the analysis of serum protein depends on the number...
Wilson's disease
corticosterone
binding capacity of thyroxine-binding globulin
peptide bonds
35. In familial hypercholesterolemia - the hallmark finding is an elevation of...
manic-depression
LDL
lipase
0
36. This hemoglobin has glucose-6-phosphate on the amino-terminal valine of the beta chain?
LDH
binding capacity of thyroxine-binding globulin
90%
A1c
37. If a drug has a half-life of 7 hours - how many doses given at 7-hour intervals does it usually take to achieve a steady state or plateau level?
5
enzyme immunoassay
exchange of amino and keto groups
metabolic acidosis
38. The methodology based on the amount of energy absorbed by a subtance as a function of its concentration and using a specific source of the same material as the substance analyzed is...
there is an absence of correlation
atomic absorption
respiratory acidosis
brain
39. This diseases results from a familial absence of high-density lioprotein
impaired response to ACTH stimulation
growth - third trimester of pregnancy
porphyrin and porphobilinogen screen
Tangier
40. Assay of transketolase activity in blood is used to detect deficiency of...
endogenous triglycerides
acute intermittent porphyria
decreased lecithin
thiamine
41. Four children are admitted with malaise - anorexia - and abdominal pain. Further evaluations reveal mild anemia - erythrocyte basophilic stippling - and profound pica habits. Poisoning by which heavy metal is most likely responsible?
glucose oxidase
L/S ratio > 3.5
lead
LDL
42. The stimulant that causes localized sweating for the sweat test is...
intestinal malabsorption
benzoylecogine
pilocarpine
T4 by RIA
43. A potentiometric electrode that measures an analyte that passes through a selectively premeable membrane and rapidly enters into an equilibrium with an electrolyte solution is...
pCO2
triglycerides
chloride
monitoring the course of a known cancer
44. A serum potassium is 19.5 mg/100 mL. This value is equal to how many mEq/L (MW of K = 39)?
improving state of metabolic control (as indicated by fructosamine)
5
120 minutes
a small concentration of APO-B containing lipoproteins after precipitation
45. Upon development of a thin layer chromatogram for the drug analysis - all drug spots (including the standards) had migrated with the solvent front. The most probable cause for this would be...
agarose
incorrect aqueous to nonaqueous mixture
the fetus is at risk for respiratory distress
Solute moves half the distance of the solvent front
46. To ensure an accurate ammonia level result - the specimen should be...
freezing point
5 tri 15 cholesterol 50 protein
wavelength
spun separated iced and tested immediately
47. Blood was collected in a serum separator tube from a patient who had been fasting since midnight. The time of collection was 7:00 AM. The laboratory test that should be re-collected is...
enzyme induction
corticosterone
triglycerides
growth - third trimester of pregnancy
48. The following results were obtained in a creatinine clearance evaluation: Urine concentration 84 mg/dL Urine volume 1440 mL/24 hr Serum concentration 1.4 mg/dL Body surface area 1.60 m2 (average = 1.73 m2) The creatinine cle~trance in mL/min is...
Wilson's disease
65
glass
inhibitor binds to enzyme at same site as substrate
49. An automated CK assay gives a reading that is above the limits of linearity. A dilution of the serum sample is made by adding 1 mL of serum to 9 mL of water. The instrument now rew 350 U/L. The correct report on the undiluted serum should be...
peroxidase-like activity of hemoglobin
20:1
3500
boderline results test should be repeated
50. This disease is associated with the greatest elevation of lactate dehydrogenase isoenzyme 1?
changes in the fuel
low pH
porphobilinigen SCREEN
B12 deficiency