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Test your basic knowledge |
Chemistry Certification
Start Test
Study First
Subject
:
certifications
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. The relative migration rate of proteins on cellulose acetate is based on...
2-log(T)
fraction absorbed into systemic circulation
HCT
ionic charge
2. A course of instruction is being planned to teach laboratory employees to correct simple malfunctions in selected laboratory instruments. In writing the objectives for this course - this would be most appropriate?
Tangier
g/MW
viral hepatitis
be able to detect 9/10 simple instrument malfunctions
3. The electrophoretic pattern of a plasma sample compared with a serum sample shows a...
pilocarpine
5
sharp fibrinogen peak
can be used for absorbtion - partition - ion exchange - and gel permeation chromatography
4. The normal concentration of proteins in cerebrospinal fluid - relative to serum protein - is...
<1%
CK-MB
prisms and grating
4.5
5. This enzymes catalyzes the conversion of starch to glucose and maltose
amylase
bone
65
volumetric flask
6. Isoenzyme assays are preformed to improve...
CO2 and pH elevated
specificity
pH = pKa + log (salt/acid)
acid phosphatase
7. This enzyme substrates for prostatic acid phosphatase determination results in the highest specificity
acute hepatitis
the fetus is at risk for respiratory distress
thymolpthalein monophosphate
turn off
8. Respiratory acidosis is described as a(n): ______ increase in CO2 decrease in pH
atomic absorption
100 nmol
glycerol
analyzed immediately
9. Cocaine is metabolized to...
benzoylecogine
catalyze redox reactions
100 nmol
ionization of carboxyl groups (yielding a net negative charge)
10. Testing for the diagnosis of lead poisoning should include...
lead
(testing of urine for) delta-am.. acid
carbohydrate hyperalimentation
analyzed immediately
11. The following laboratory results were obtained: Serum Calcium: Increased - Urine Calcium: Increased - Serum Phosphate: Decreased - Urine Phosphate: Increased Serum Alkaline Phosphatase: Normal or Increased These results are most compatible with...
40-50
incorrect aqueous to nonaqueous mixture
GGT
primary hyperparathyroidism
12. On immunoassays using enzyme-labeled antibodies or antigens: ___________ can be carried out with a spectrophotometer
growth - third trimester of pregnancy
chylomicrons VLDL
quantitation of label
occult blood
13. Maple syrup urine disease is characterized by an increase in this urinary amino acids
valine leucine isoleucine
ratio of distance moved by solvent to distance moved by compound
prevent phosphate interference
metabolic acidosis
14. A pH of 7.0 represents a H+ concentration of...
corticosterone
CK
hepatobiliary (obstruction?)
100 nmol
15. A patient is admitted to the emergency room in a state of metabolic alkalosis.This would be consistent with this diagnosis?
improving state of metabolic control (as indicated by fructosamine)
creatine kinase
electric current
high co2 and hco3
16. Bile acid concentrations are useful to assess...
exposure to CO
catalyze redox reactions
HDL
hepatobiliary (obstruction?)
17. A common cause of respiratory alkalosis is...
hyperventilation
phenytoin
ratio of distance moved by solvent to distance moved by compound
5
18. Analysis of erythrocytes for uroporphyrinogen I synthetase detects...
corticosterone
acute intermittent porphyria
carbohydrate hyperalimentation
chylomicrons VLDL
19. The following results were obtained in a creatinine clearance evaluation: Urine concentration 84 mg/dL Urine volume 1440 mL/24 hr Serum concentration 1.4 mg/dL Body surface area 1.60 m2 (average = 1.73 m2) The creatinine cle~trance in mL/min is...
elevated lactic acid - elevated pyruvate
65
hyperventilation
primidone
20. This method employs a highly specific antibody to thyroxine
bilirubindiglucuronide
thiamine
T4 by RIA
HPLC analysis of porpobilinogen on 24hr urine
21. Technical problems encountered during the collection of an amniotic fluid specimen caused doubt as to whether the specimen was amniotic in origin. This procedure would establish that the fluid is amniotic in origin
SD over mean
creatinine
270
Tay-sachs
22. The expected blood gas results for a patient in chronic renal failure would match the pattern of...
metabolic acidosis
increased vasoconstriction
glycerol
cmpds based on molecular weight and size
23. Zinc protoporphyrin or free erythrocyte protoporphyrin measurements are useful to assess blood concentrations of...
1:5
there is an absence of correlation
lead
endosmosis
24. A fresh urine sample is received for "porphyrins" or "porphyria" without further information or specifications. Initial analysis should include...
dirty applicators
porphyrin and porphobilinogen screen
3500
maintain colloidal osmotic pressure
25. One international unit of enzyme activity is the amount of enzyme that - under specified reaction conditions of substrate concentration - pH - and temperature - causes utilization of substrate at the rate of...
nephelometry
20:1
one micromole/minute
accuracy
26. Specimens for blood gas determination should be drawn into a syringe containing...
heparin
cmpds based on molecular weight and size
enzyme immunoassay
pituitary
27. A critically ill patient becomes comatose. The physician believes the coma is due to hepatic failure. The assay most helpful in this diagnosis is...
A1c
ammonia
parathyroid hormone
quantitation of label
28. This is a regulatory hormone.
nondiagnostic for MS
3500
parathyroid hormone
sharp fibrinogen peak
29. The TRH (thyrotropin-releasing hormone) stimulation test is useful in assessing...
hyperthyroidism
thyroxine binding globulin
the fetus is at risk for respiratory distress
metabolic acidosis
30. Characteristic of the Bence Jones protein that is used to distinguish it from other urinary proteins is its solubility...
specificity
@ 100
emphysema
quantitation of label
31. The most specific enzyme test for acute pancreatitis is...
metabolic acidosis
lipase
BUN 80
TSH
32. A patient with type I insulin-dependent diabetes mellitus has the following results: Fasting blood glucose: 150 mg/dL (70-110 rng/dL) Hemoglobin A1c: 25% (6.0%-19.5%) Fructosamine: 3.0 mmol/L ( 2.0-5.3 mmol/L)
iron deficiency anemia
improving state of metabolic control (as indicated by fructosamine)
have a negative charge
impaired response to ACTH stimulation
33. The enzyme present in almost all tissues that may be separated by electrophoresis into five components is...
cancel test
LDH
draw blood for glucose and discontinue test
lead
34. The most important buffer pair in plasma is the...
iron hemochromatosis
bicarbonate carbonic acid
pO2 increased HCO3 decreased
@ 100
35. The most common type of congenital adrenal hyperplasia associated with increased plasma concentrations of 17 a-hydroxyprogesterone and increased urinary excretion of pregnanetriol is...
low pH
obstructive jaundice
21-hydroxylase deficiency
thyroxine
36. One international unit of enzyme activity is the amount of enzyme that - under specified reaction conditions of substrate concentration - pH - and temperature - causes utilization of substrate at the rate of...
specimen exposure to light
enzyme immunoassay
1 micromole per minute
porphobilinogen synthetase
37. Following overnight fasting - hypoglycemia in adults is defined as a glucose of...
measures one ion more than others
electric current
128
<45
38. The main reason for suboptimal drug levels in therapeutic drug monitoring is...
100 nmol
patient noncompliance
no ice clots bubbles
respiratory acidosis
39. In developing the reference for a new EIA for CEA - the range for the normal population was broader than that published by the vendor. Controls are acceptable with a narrow coefficient of variation. This may be explained by...
inclusion of smokers and nonsmokers in the study population
1 micromole per minute
bicarbonate buffer
trig
40. In familial hypercholesterolemia - the hallmark finding is an elevation of...
20:1
65
spun separated iced and tested immediately
LDL
41. Measurement of total T4 by competitive protein binding or displacement is based on the specific binding properties of...
glass
acid phosphatase
thyroxine binding globulin
BUN 80
42. This calcium procedure utilizes lanthanum chloride to emliminate iterfering substances
LDL
endogenous triglycerides
atomic absorption
inhibitor binds to enzyme at same site as substrate
43. The formation of estriol in a pregnant woman is dependent on...
attaching them to protein molecules
remove excess unbound iron
increased vasoconstriction
fetal and placenta function
44. The definitive diagnosis of primary adrenal insufficiency requires demonstration of...
band width
WITHOUT a disease with a negative test
impaired response to ACTH stimulation
CK-MB
45. If a drug has a half-life of 7 hours - how many doses given at 7-hour intervals does it usually take to achieve a steady state or plateau level?
5
can be used for absorbtion - partition - ion exchange - and gel permeation chromatography
100nmol
GGT
46. The biologically most active - naturally occuring androgen is...
para-hydroxylphenyl...
thyroxine
testosterone
iron deficiency anemia
47. Turbidity in serum suggests elevation of...
0
chylomicrons
Hb S
Tay-sachs
48. The reason carbon monoxide is so toxic is because it...
glucose oxidase
5
g/MW
200x affinity for oxygen
49. When the exact concentration of the solute of a solution is known and is used to evaluate the concentration of an unknown solution - the known solution is...
standard
L/S ratio > 3.5
low pH
show a decrease in glycosylated hgb
50. Given the following results: Alkaline phosphatase Marked increase Aminotransferase Slight increase Aspartate aminotransferase Slight increase Alanine gamma-glutamyl transferase Marked increase This is most consistent with...
valine leucine isoleucine
sharp fibrinogen peak
endosmosis
obstructive jaundice