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Test your basic knowledge |
Chemistry Certification
Start Test
Study First
Subject
:
certifications
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. A 45-year-old woman complains of fatigue - heat intolerance - and hair loss. Serum thyroxine and 125I-T3 resin uptake are abnormally low. What test would confirm that this is a pituitary deficiency?
TSH
didymium filter
no ice clots bubbles
LDL
2. The stimulant that causes localized sweating for the sweat test is...
CK-MB
nondiagnostic for MS
pilocarpine
acute hepatitis
3. Oligoclonal bands are present on electrophoresis of concentrated CSF and also on concurrently tested serum of the same patient. The proper interpretation is...
potassium dichromate in SA
Mg
nondiagnostic for MS
5
4. Respiratory acidosis is described as a(n): ______ increase in CO2 decrease in pH
TSH
porphobilinogen screen
glycerol
growth - third trimester of pregnancy
5. In a normal individual - injection of thyrotropin-releasing hormone (TRH) causes an increase in blood concentrations of this hormone
tissue and serum levels need to reach equilibrium
3500
decreased lecithin
Prolactin
6. When separating serum proteins by cellulose acetate electrophoresis using veronal buffer at pH 8.6 - beta globulin migrates...
Calcium - phosphorus
65
T4 by RIA
faster than gamma
7. The osmolality of a urine or serum specimen is measured by a change in the...
sharp cutoff filter
100nmol
exposure to CO
freezing point
8. In competitive inhibition of an enzyme reaction the...
Mg
inhibitor binds to enzyme at same site as substrate
the same as plasma glucose
measure the total volume
9. The function of the major lipid components of the very low density lipoproteins (VLDL) is to transport...
pH pCO2 pO2
1 micromole per minute
endogenous triglycerides
@ 100
10. Most automated blood gas analyzers directly measure...
ceruplasmin
thyroxine binding globulin
pH pCO2 pO2
200
11. The biuret reaction for the analysis of serum protein depends on the number...
peptide bonds
corticosterone
5
creatinine clearance
12. Zinc protoporphyrin or free erythrocyte protoporphyrin measurements are useful to assess blood concentrations of...
hepatobiliary (obstruction?)
TSH
acute intermittent porphyria
lead
13. The following results were obtained in a creatinine clearance evaluation: Urine concentration 84 mg/dL Urine volume 1440 mL/24 hr Serum concentration 1.4 mg/dL Body surface area 1.60 m2 (average = 1.73 m2) The creatinine cle~trance in mL/min is...
standard
porphyrin and porphobilinogen screen
65
correct for variations in flame and atomizer
14. What specimen preparation is commonly used to perform the alkaline phosphatase isoenzyme determination?
serum aliquots - one heated
9
high carbohydrate diet for 3 days
ammonia
15. A pH of 7.0 represents a H+ concentration of...
biuret
100 nmol
triglycerides
volumetric flask
16. The formula for calculating the amount of moles of a chemical?
occult blood
g/MW
acute intermittent porphyria
alkaline picrate
17. Phenobarbital is a metabolite of...
65
spun separated iced and tested immediately
primidone
pituitary
18. To ensure an accurate ammonia level result - the specimen should be...
maintain colloidal osmotic pressure
spun separated iced and tested immediately
O2
multiplied by 4
19. This chemical determination may be of help in establishing the presence of seminal fluid
acid phosphatase
primidone
growth - third trimester of pregnancy
TSH
20. As part of a hyperlipidemia screening program - the following results were obtained on a 25 year old woman 6 hours after eating:Triglycerides = 260 mg/dLCholesterol = 120 mg/dL - This is the BEST interpretation of these results?
fresh morning urine for delta-aminolevulinic acid
peroxidase-like activity of hemoglobin
cholesterol normal triglycerides elevated
32
21. An Rf value of 0.5 in thin-layer chromatography means...
O2
porphobilinogen synthetase
Solute moves half the distance of the solvent front
1 micromole per minute
22. The following data were obtained from a cellulose acetate protein electrophoresis scan: Albumin area 75 units Gamma globulin area 30 units Total area 180 units Total protein 6.5 g/dL The gamma globulin content in g/dL is...
acid phosphatase
apoenzyme
sharp fibrinogen peak
1.1
23. The ability of a procedure to measure only the component(s) it claims to measure is called...
specificity
sodium
thiamine
standard
24. The osmolality of a urine or serum specimen is measured by a change in the...
freezing point
turn off
100 nmol
cholesterol normal triglycerides elevated
25. While performing a serum lithium determination on a flame photometer with cesium as the internal standard - the technologist noticed that there was a flickering flame. The most probable cause of this problem is...
changes in the fuel
conjugated hyperbilirubinemia - hepatocellular obstruction
NADH
ratio of distance moved by solvent to distance moved by compound
26. The following five sodium control values (mEq/L) were obtained:140 - 135 - 138 - 140 - 142Calculate the coefficient of variation.
serum cortisol > 15
bilirubin
1.9
TLC
27. Patients with Cushing's syndrome exhibit...
apoenzyme
serum cortisol > 15
acute hepatitis
cancel test
28. If a drug has a half-life of 7 hours - how many doses given at 7-hour intervals does it usually take to achieve a steady state or plateau level?
acid phosphatase
5mg higher
binding capacity of thyroxine-binding globulin
5
29. The definitive diagnosis of primary adrenal insufficiency requires demonstration of...
impaired response to ACTH stimulation
draw blood for glucose and discontinue test
amytriptyline 104
no decrease in serum growth hormone after 90 minutes
30. Enzymes used in the diagnosis of acute pancreatitis?
adding an acid stabilizer
can be used for absorbtion - partition - ion exchange - and gel permeation chromatography
amylase and lipase
phenytoin
31. An HPLC operator notes that the column pressure is too high - is rising too rapidly - and the recorder output is not producing normal peaks. The most probable cause of the problem is...
3500
effluent line is obstructed
testosterone
tissue and serum levels need to reach equilibrium
32. The normal concentration of proteins in cerebrospinal fluid - relative to serum protein - is...
properties of the membrane
<1%
cancel test
pO2 increased HCO3 decreased
33. The protein portion of an enzyme complex is called the...
adding an acid stabilizer
apoenzyme
nephelometry
viral hepatitis
34. In the assay of lactate dehydrogenase - this product is actually measured
bilirubindiglucuronide
<45
NADH
BUN 80
35. In a double-beam photometer - the additional beam is used to...
thiamine
correct for variations in light intensity
Solute moves half the distance of the solvent front
multiplied by 4
36. This is a glycolytic enzyme that catalyzes the cleavage of fructose-1 - 6-diphosphate to glyceraldehyde-3-phosphate and dihydroxyacetone phosphate
aldolase
electric current
amylase and lipase
heparin
37. The test for adrenal cortical hyperfunction that has the greatest diagnostic sensitivity is measurement of...
no decrease in serum growth hormone after 90 minutes
urinary free cortisol
correct for variations in light intensity
thiamine
38. Before unconjugated bilirubin can react with Ehrlich's diazo reagent - this must be added
cysteine
methyl alcohol
properties of the membrane
CML
39. A potassium level of 6.8 mEq/L is obtained. Before reporting the results - the first step the technologist should take is to...
thiamine
check serum for hemolysis
hepatobiliary (obstruction?)
monitoring the course of a known cancer
40. A patient is admitted with biliary cirrhosis. If a serum protein electrophoresis is preformed - these globulin fractions will be most elevated?
iron deficiency anemia
Hb S
beta
conjugated hyperbilirubinemia - hepatocellular obstruction
41. One means of checking a spectrophotometer wavelength calibration in the visible range is by using a...
can be separated into distinct phenotypes
LDL
didymium filter
chemical ionization matrix
42. The general types of interference in atomic absorption spectrophotometry...
chemical ionization matrix
CML
1 micromole per minute
spun separated iced and tested immediately
43. In performing a spinal fluid protein determination - the specimen is diluted 1 part spinal fluid to 3 parts saline to obtain a result low enough to measure. To calculate the protein concentration the result must be...
L/S ratio > 3.5
creatinine
multiplied by 4
adding an acid stabilizer
44. Rickets is associated with deficiency of...
Mg
measurement of absorbance at 450
D
Calcium - phosphorus
45. In respiratory acidosis - a compensatory mechanism is the increase in...
128
Hb S
plasma bicarbonate
9
46. In spectrophotometric determination - this is the formula for calculating the absorbance of a solution
correct for variations in light intensity
thiamine
absorptivity x light path x concentration
didymium filter
47. The measurement of light scattered by particles in the sample is the principle of...
200x affinity for oxygen
nephelometry
dirty electrodes
volumetric flask
48. A 24-hour urine specimen (total volume = 1136 mL) is submitted to the laboratory for quantitative urine protein. Calculate the amount of protein excreted per day - if the total protein is 52 mg/dL.
measure the total volume
prevent phosphate interference
urinary free cortisol
591
49. Detection of carriers of hereditary coproporphyria should include analysis of...
5
3500
C3 complement
fresh morning urine for delta-aminolevulinic acid
50. Total iron-binding capacity measures the serum iron transporting capacity of...
transferrin
enzyme immunoassay
A1
carbs