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Chemistry Certification
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Subject
:
certifications
Instructions:
Answer 50 questions in 15 minutes.
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study here
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Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. The following results were obtained in a creatinine clearance evaluation: Urine concentration 84 mg/dL Urine volume 1440 mL/24 hr Serum concentration 1.4 mg/dL Body surface area 1.60 m2 (average = 1.73 m2) The creatinine cle~trance in mL/min is...
T4 by RIA
enzyme immunoassay
65
lipase
2. 4 mL of water is added to 1 mL of serum. This represents this serum dilutions
100nmol
1:5
iron deficiency anemia
BUN 80
3. A pH of 7.0 represents a H+ concentration of...
porphobilinogen synthetase
growth - third trimester of pregnancy
100nmol
bilirubindiglucuronide
4. A fasting serum sample from an asymptomatic 43-year-old woman is examined visually chemically with the following results: Initial appearance of serum: Milky Appearance of serum after overnight refrigeration: Cream layer over turbid serum Triglyceri
chylomicrons VLDL
hyperthyroidism
bilirubindiglucuronide
volumetric flask
5. Ninety percent of the copper present in plasma is bound to...
occult blood
high carbohydrate diet for 3 days
porphobilinigen SCREEN
ceruplasmin
6. Oligoclonal bands are present on electrophoresis of concentrated CSF and also on concurrently tested serum of the same patient. The proper interpretation is...
nondiagnostic for MS
Solute moves half the distance of the solvent front
21-hydroxylase deficiency
without a disease with a negative test result
7. A fresh urine sample is received for "porphyrins" or "porphyria" without further information or specifications. Initial analysis should include...
elevated lactic acid - elevated pyruvate
porphyrin and porphobilinogen screen
sample exposed to light
standard
8. In a double-beam photometer - the additional beam is used to...
correct for variations in light intensity
no ice clots bubbles
1:5
glucose oxidase
9. A 45-year-old woman has a fasting serum glucose concentration of 95 mg/dL and a 2-hour postprandial glucose concentration of 105 mg/dL. The statement that best describes this patient's fasting serum glucose concentration is...
hyperthyroidism
parathyroid
normal - liver breakdown
trig
10. Gel filtration chromatography is used to separate...
viral hepatitis
cmpds based on molecular weight and size
one micromole/minute
inclusion of smokers and nonsmokers in the study population
11. This elevates carboxyhemoglobin?
effluent line is obstructed
primidone
parathyroid
exposure to CO
12. The enzyme present in almost all tissues that may be separated by electrophoresis into five components is...
GFR
TSH
LDH
measures one ion more than others
13. A patient had the following serum results: Na+ 140 mEq/L K+ 4.0 mEq/L Glucose 95 mg/dL BUN 10 mg/dL Which osmolality is consistent with these results?
diet
270
ALP with fresh draw
the fetus is at risk for respiratory distress
14. The biuret reaction for the analysis of serum protein depends on the number...
can be separated into distinct phenotypes
exposure to CO
peptide bonds
serum aliquots - one heated
15. A stool specimen that appears black and tarry should be tested for the presence of...
occult blood
respiratory acidosis
glycerol
CO2 and pH elevated
16. Most automated blood gas analyzers directly measure...
pH pCO2 pO2
parathyroid hormone
2-log(T)
multiplied by 4
17. A 25-year-old man became nauseated and vomited 90 minutes after receiving a standard 75-g carbohydrate dose for an oral glucose tolerance test. The best course of action is...
draw blood for glucose and discontinue test
ceruplasmin
1.9
show a decrease in glycosylated hgb
18. An electrophoretic separation of lactate dehydrogenase isoenzymes that demonstrates an elevation in LD-l and LD-2 in a "flipped" pattern is consistent with...
manic-depression
chloride
MI
breast cancer
19. The concentration of serum carotene is affected MOST by...
bilirubin
diet
act as carriers for ions
bone
20. This diseases results from a familial absence of high-density lioprotein
Tangier
1.1
TSH
TSH
21. Cerebrospinal fluid for glucose assay should be...
specificity
1 micromole per minute
analyzed immediately
obstructive jaundice
22. The test for adrenal cortical hyperfunction that has the greatest diagnostic sensitivity is measurement of...
urinary free cortisol
hyperthyroidism
amytriptyline 104
transferrin
23. When myocardial infarction occurs - the first enzyme to become elevated is...
CK
specimen exposure to light
prisms and grating
para-hydroxylphenyl...
24. In the liver - bilirubin is converted to...
1 mol/kg
bilirubindiglucuronide
HDL
Prolactin
25. Kernicterus is an abnormal accumulation of bilirubin in...
sharp cutoff filter
dirty applicators
1:5
brain
26. The osmolal gap is defined as measured Osm/kg minus the calculated Osm/kg. The average osmolal gap is near...
0
aldolase
primary hyperparathyroidism
creatinine
27. In the fasting state - the arterial and capillary blood glucose concentration varies from the venous glucose concentration by approximately how many mg/dL?
peroxidase-like activity of hemoglobin
coulometry
can be separated into distinct phenotypes
5mg higher
28. In using ion-exchange chromatographicbmethods - falsely increased levels of Hgb A1c will be demonstrated in presence of...
glass
intestinal malabsorption
Hb S
TSH
29. How many grams of sodium chloride are needed to prepare 1 L of 0.9% normal saline?
dirty applicators
check serum for hemolysis
9
M subunit is inactivated
30. Sixty to seventy-five percent of the plasma cholesterol is transported by...
band width
LDL
200
properties of the membrane
31. An automated method for measuring chloride that generates silver ions in the reaction is...
coulometry
diet
lipase
C
32. Measurement of the serum acid phosphatase is used to detect neoplastic disease of the...
prostate
adding an acid stabilizer
TLC
monitoring the course of a known cancer
33. The regulation of calcium and phosphorus metabolism is accomplished by which gland?
bilirubin
volumetric flask
100 nmol
parathyroid
34. The main reason for suboptimal drug levels in therapeutic drug monitoring is...
120 minutes
g/MW
band width
patient noncompliance
35. The reason carbon monoxide is so toxic is because it...
placenta
200x affinity for oxygen
urobilin
endogenous triglycerides
36. In respiratory acidosis - a compensatory mechanism is the increase in...
ionic charge
plasma bicarbonate
TSH
4.5
37. A critically ill patient becomes comatose. The physician believes the coma is due to hepatic failure. The assay most helpful in this diagnosis is...
monitoring the course of a known cancer
oxalacetate to malate
ammonia
hemolysis
38. A 9-month-old boy from Israel has gradually lost the ability to sit up and develops seizures. He has an increased amount of a phospholipid called GM2-ganglioside in his neurons - and he lacks the enzyme hexosaminidase A in his leukocytes. These findi
acute hepatitis
run a new set of controls
glucose oxidase
Tay-sachs
39. This serum protein migrates with the beta-globulins on cellulose acetate at pH 8.6...
C3 complement
cmpds based on molecular weight and size
fraction absorbed into systemic circulation
serum cortisol > 15
40. A serum sample was assayed for bilirubin at 10 AM and the result was 12 mg/dL. The same sample was retested at 3 PM. The result now is 8 mg/dL. The most likely explanation for this discrepancy is...
1 micromole per minute
monitoring the course of a known cancer
sample exposed to light
digoxin
41. Hydrogen ion concentration (pH) in blood is usually determined by means of these electrodes?
standard
fall in pH - rise in pCO2
glass
decreased lecithin
42. Which two conditions can "physiologically" elevate serum alkaline phosphatase?
mg/ml
growth - third trimester of pregnancy
catalyze redox reactions
elevated lactic acid - elevated pyruvate
43. In the assay of lactate dehydrogenase - this product is actually measured
catalyze redox reactions
show a decrease in glycosylated hgb
apoenzyme
NADH
44. Lithium therapy is widely used in the treatment of...
HCT
(testing of urine for) delta-am.. acid
5
manic-depression
45. A common cause of a falsely increased LD1 fraction of lactic dehydrogenase is...
hemolysis
freezing point
low pH
TSH
46. Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) are both elevated in this disease
alpha 2 beta
without a disease with a negative test result
viral hepatitis
LDH
47. Enzymes used in the diagnosis of acute pancreatitis?
methadone
amylase and lipase
M subunit is inactivated
peroxidase-like activity of hemoglobin
48. This enzyme substrates for prostatic acid phosphatase determination results in the highest specificity
impaired response to ACTH stimulation
atomic absorption
thymolpthalein monophosphate
nephelometry
49. TSH is produced by the...
fresh morning urine for delta-aminolevulinic acid
changes in the fuel
pituitary
faster than gamma
50. Clinical assays for tumor markers are the most important for...
32
alpha 2 beta
monitoring the course of a known cancer
LDL
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