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Test your basic knowledge |
Chemistry Certification
Start Test
Study First
Subject
:
certifications
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. The normal concentration of proteins in cerebrospinal fluid - relative to serum protein - is...
pilocarpine
can be separated into distinct phenotypes
<1%
trig
2. Characteristic of the Bence Jones protein that is used to distinguish it from other urinary proteins is its solubility...
@ 100
impaired response to ACTH stimulation
prostate
creatine kinase
3. If a drug has a half-life of 7 hours - how many doses given at 7-hour intervals does it usually take to achieve a steady state or plateau level?
TSH
A1
CK
5
4. This applies to cryoscopic osmometry
peptide bonds
bicarbonate buffer
absorptivity x light path x concentration
Temperature is a function of the number of particles in solution
5. The definitive diagnosis of primary adrenal insufficiency requires demonstration of...
correct for variations in light intensity
methyl alcohol
prisms and grating
impaired response to ACTH stimulation
6. Most drugs and intracellular metabolites measured by radioimmunoassay have molecular weights between 200 and 1000 and can be made immunogenic by...
attaching them to protein molecules
@ 100
sodium potassium chloride CO2
hepatobiliary (obstruction?)
7. The chemical composition of HDL- cholesterol corresponds to...
absorptivity x light path x concentration
endosmosis
GFR
5 tri 15 cholesterol 50 protein
8. Aminotransferase enzymes catalyze the...
3500
measurement of absorbance at 450
thymolpthalein monophosphate
exchange of amino and keto groups
9. In electrophoresis of proteins - when the sample is placed in an electric field connected to a buffer of pH 8.6 - all of the proteins...
dirty applicators
porphobilinigen SCREEN
1.1
have a negative charge
10. One international unit of enzyme activity is the amount of enzyme that - under specified reaction conditions of substrate concentration - pH - and temperature - causes utilization of substrate at the rate of...
Wilson's disease
one micromole/minute
biuret
chylomicrons VLDL
11. Serum and urine copper levels are assayed on a hospital patient with the following results: Patient Serum Cu: 58 ug/dL; Reference Value:70-140 ug/dL Patient Urine Cu: 83 ug/dL ; Reference Value: < 40 ug/dL This is most consistent with...
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on line
183
12. This enzymes catalyzes the conversion of starch to glucose and maltose
elevated lactic acid - elevated pyruvate
valine leucine isoleucine
amytriptyline 104
amylase
13. Blood received in the laboratory for blood gas analysis must meet these requirements
no ice clots bubbles
digoxin
impaired response to ACTH stimulation
1.9
14. If the correlation coefficient (r) of two variables is zero...
there is an absence of correlation
ionization of carboxyl groups (yielding a net negative charge)
CK
methadone
15. A potentiometric electrode that measures an analyte that passes through a selectively premeable membrane and rapidly enters into an equilibrium with an electrolyte solution is...
no decrease in serum growth hormone after 90 minutes
1 mol/kg
pCO2
0
16. A psychiatric patient was experiencing sever depression - but responded to treatment with amitriptyline with no apparent side effects. A blood sample was sent to the laboratory for therapeutic monitoring. Which drug level would be MOST reflective of
TSH
amytriptyline 104
carbohydrate hyperalimentation
bicarbonate buffer
17. In thin layer chromatography - the Rf value for a compound is given by the...
ratio of distance moved by solvent to distance moved by compound
amytriptyline 104
Temperature is a function of the number of particles in solution
methadone
18. The fast hemoglobin fraction is...
A1
thymolpthalein monophosphate
Wilson's disease
analyzed immediately
19. A reciprocal relationship exists between...
Calcium - phosphorus
B12 deficiency
20:1
decreased lecithin
20. These enzymes of heme biosynthesis are inhibited by lead
run a new set of controls
sharp fibrinogen peak
thymolpthalein monophosphate
porphobilinogen synthetase
21. Clinical assays for tumor markers are the most important for...
adding an acid stabilizer
<1%
monitoring the course of a known cancer
Temperature is a function of the number of particles in solution
22. Unless blood gas measurements are made immediately after sampling - in vitro glycolysis of the blood causes a...
primary hyperparathyroidism
fall in pH - rise in pCO2
low pH
plasma bicarbonate
23. Nephelometers measure light...
sodium potassium chloride CO2
scattered at a right angle
run a new set of controls
acid phosphatase
24. The following results were obtained in a creatinine clearance evaluation: Urine concentration 84 mg/dL Urine volume 1440 mL/24 hr Serum concentration 1.4 mg/dL Body surface area 1.60 m2 (average = 1.73 m2) The creatinine cle~trance in mL/min is...
GLC
cholesterol normal triglycerides elevated
65
5
25. The presence of this isoenzymes indicates acute myocardial damage
measure the total volume
CK-MB
chylomicrons VLDL
crigler
26. The osmolal gap is defined as measured Osm/kg minus the calculated Osm/kg. The average osmolal gap is near...
sodium
0
decreased lecithin
bicarbonate buffer
27. Upon completion of a run of cholesterol tests - the technician recognizes that the controls are not within the two standard deviations confidence range. What is the appropriate course of action
run a new set of controls
porphobilinogen screen
viral hepatitis
creatinine clearance
28. The identification of Bence Jones protein is best accomplished by...
spun separated iced and tested immediately
TSH
effluent line is obstructed
immunofixation
29. An electrophoretic separation of lactate dehydrogenase isoenzymes that demonstrates an elevation in LD-l and LD-2 in a "flipped" pattern is consistent with...
iron deficiency anemia
MI
NADH
carbs
30. This would be an example of a glucose-specific colorimetric method
thiamine
glucose oxidase
HPLC analysis of porpobilinogen on 24hr urine
hyperthyroidism
31. In monitoring glomerular function - this test has the highest sensitivity
creatinine clearance
prevent phosphate interference
boderline results test should be repeated
32
32. The principle of the occult blood test depends on the...
(testing of urine for) delta-am.. acid
run a new set of controls
porphobilinogen synthetase
peroxidase-like activity of hemoglobin
33. The formula for calculating absorbance given the percent transmittance (%T) of a solution
2-log(T)
measure the total volume
591
digoxin
34. Enzymes used in the diagnosis of acute pancreatitis?
increase in total circulating T4
NADH
amylase and lipase
can be used for absorbtion - partition - ion exchange - and gel permeation chromatography
35. A patient has the following results: Patient Values : Reference Values: Serum iron 250 ug/dL 60-150 ug/dL TIBC 350 ug/dL 300-35O ug/dL The best conclusion is that this patient has...
9
iron hemochromatosis
O2
endogenous triglycerides
36. An Rf value of 0.5 in thin-layer chromatography means...
low pH
hyperventilation
340
Solute moves half the distance of the solvent front
37. The enzyme that exists chiefly in skeletal muscle - heart - and brain; is grossly elevated in active muscular dystrophy; and rises early in myocardial infarction is...
creatine kinase
increase in total circulating T4
thiamine
respiratory acidosis
38. Spectrophotometers isolate a narrow band pass by means of...
obstructive jaundice
32
C3 complement
prisms and grating
39. This elevates carboxyhemoglobin?
exposure to CO
fresh morning urine for delta-aminolevulinic acid
chemical ionization matrix
porphyrin and porphobilinogen screen
40. Rickets is associated with deficiency of...
have a negative charge
D
F
minimize the effects of interference
41. Sixty to seventy-five percent of the plasma cholesterol is transported by...
LDL
atomic absorption
manic-depression
immunofixation
42. The osmolality of a urine or serum specimen is measured by a change in the...
glucose
lipase
amylase and lipase
freezing point
43. The serum glucose concentration of a diabetic patient undergoing a 2-hour glucose tolerance test should return to the baseline (fasting level) after a minimum of...
120 minutes
amylase
pCO2
wavelength
44. A thick white turbid specimen was received in the laboratory labeled as pericardial fluid. A microscopic examination was performed - and the differential included 90% PMNs. The fluid is...
glycerol
parathyroid
plasma bicarbonate
purulent
45. When separating serum proteins by cellulose acetate electrophoresis using veronal buffer at pH 8.6 - beta globulin migrates...
breast cancer
faster than gamma
glucose
bilirubin
46. A serum sample was assayed for bilirubin at 10 AM and the result was 12 mg/dL. The same sample was retested at 3 PM. The result now is 8 mg/dL. The most likely explanation for this discrepancy is...
sample exposed to light
Solute moves half the distance of the solvent front
amylase
apoenzyme
47. A 9-month-old boy from Israel has gradually lost the ability to sit up and develops seizures. He has an increased amount of a phospholipid called GM2-ganglioside in his neurons - and he lacks the enzyme hexosaminidase A in his leukocytes. These findi
didymium filter
check serum for hemolysis
Tay-sachs
dihydroxyacetone side chain
48. A test request slip indicates that an acute porphyric attack is suspected clinically. Analysis should include...
Temperature is a function of the number of particles in solution
dirty applicators
porphobilinogen screen
endosmosis
49. Respiratory acidosis is described as a(n): ______ increase in CO2 decrease in pH
purulent
Wilson's disease
glycerol
para-hydroxylphenyl...
50. Serum concentrations of vitamin B12 are elevated in...
diet
GGT
CML
high carbohydrate diet for 3 days