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Test your basic knowledge |
Chemistry Certification
Start Test
Study First
Subject
:
certifications
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. TSH is produced by the...
hemolysis
without a disease with a negative test result
parathyroid
pituitary
2. Blood was collected in a serum separator tube from a patient who had been fasting since midnight. The time of collection was 7:00 AM. The laboratory test that should be re-collected is...
0
patient noncompliance
thyroxine binding globulin
triglycerides
3. A new method is being evaluated. A recovery experiment is performed with the following results: 0.9 mL serum sample + 0.1 mL H20 = 89 mEq/L 0.9 mL serum sample + 0.1 mL analyte std. @ 800 mEq/L = 161 mEq/L The percent recovery of the added analyt
90%
changes in the fuel
pH = pKa + log (salt/acid)
A1c
4. Unless blood gas measurements are made immediately after sampling - in vitro glycolysis of the blood causes a...
transferrin
fall in pH - rise in pCO2
parathyroid
correct for variations in flame and atomizer
5. A serum sample was assayed for bilirubin at 10 AM and the result was 12 mg/dL. The same sample was retested at 3 PM. The result now is 8 mg/dL. The most likely explanation for this discrepancy is...
LDL
sample exposed to light
fetal and placenta function
creatinine
6. Isoenzyme assays are preformed to improve...
parathyroid
specificity
HCT
measures one ion more than others
7. A blood gas sample was sent to the lab on ice - and a bubble was present in the syringe. The blood had been exposed to room air for at least 30 minutes. The following change in blood gases occurred...
glass
no decrease in serum growth hormone after 90 minutes
increased O2 decreased HCO3
<45
8. One international unit of enzyme activity is the amount of enzyme that - under specified reaction conditions of substrate concentration - pH - and temperature - causes utilization of substrate at the rate of...
one micromole/minute
LDL
check serum for hemolysis
C3 complement
9. When the exact concentration of the solute of a solution is known and is used to evaluate the concentration of an unknown solution - the known solution is...
oxalacetate to malate
SD over mean
standard
1.1
10. The most widely employed screening technique for drug abuse is...
aldolase
brain
thyroxine
TLC
11. When separating serum proteins by cellulose acetate electrophoresis using veronal buffer at pH 8.6 - beta globulin migrates...
porphobilinogen synthetase
decreased lecithin
faster than gamma
5mg higher
12. A patient is admitted with biliary cirrhosis. If a serum protein electrophoresis is preformed - these globulin fractions will be most elevated?
whole blood can be used
check serum for hemolysis
specificity
beta
13. The buffering capacity of blood is maintained by a reversible exchange process between bicarbonate and...
creatine kinase
thiamine
chloride
para-hydroxylphenyl...
14. In automated methods utilizing a bichromatic analyzer - dual wavelengths are employed to...
minimize the effects of interference
normal - liver breakdown
digoxin
C3 complement
15. A test request slip indicates that an acute porphyric attack is suspected clinically. Analysis should include...
21-hydroxylase deficiency
porphobilinigen SCREEN
monitoring the course of a known cancer
ALP with fresh draw
16. A blood creatinine value of 5.0 mg/dL is most likely to be found with this blood value?
porphobilinogen screen
HCT
whole blood can be used
BUN 80
17. Patients with Cushing's syndrome exhibit...
atomic absorption
inclusion of smokers and nonsmokers in the study population
serum cortisol > 15
biuret
18. The following five sodium control values (mEq/L) were obtained:140 - 135 - 138 - 140 - 142Calculate the coefficient of variation.
1.9
porphobilinogen screen
patient noncompliance
thyroxine binding globulin
19. The following laboratory results were obtained on arterial blood: Sodium 136 mEq/L pH 7.32 Potassium 4.4 mEq/L PCO2 79 mm Hg Chloride 92 mEq/L Bicarbonate 40 mEq/L These results are most compatible with...
respiratory acidosis
atomic absorption
atomic absorption
lead
20. Zinc protoporphyrin or free erythrocyte protoporphyrin measurements are useful to assess blood concentrations of...
lead
acute intermittent porphyria
1.9
bilirubindiglucuronide
21. Quantitation of NA+ and K+ by ion-selective electrode is more rapid than flame photometry because...
C
adding an acid stabilizer
whole blood can be used
testing heparinized plasma
22. The protein portion of an enzyme complex is called the...
hemolysis
apoenzyme
didymium filter
270
23. A patient had the following serum results: Na+ 140 mEq/L K+ 4.0 mEq/L Glucose 95 mg/dL BUN 10 mg/dL Which osmolality is consistent with these results?
parathyroid
alkaline picrate
A1
270
24. Maple syrup urine disease is characterized by an increase in this urinary amino acids
peptide bonds
alpha 2 beta
WITHOUT a disease with a negative test
valine leucine isoleucine
25. A carbonate salt used to control manic-depressive disorders is...
GGT
analyzed immediately
lithium
measurement of absorbance at 450
26. Blood samples were collected at the beginning of an exercise class and after 30 minutes of aerobic activity. This would be most consistent with the postexercise sample
decreased lecithin
elevated lactic acid - elevated pyruvate
endogenous triglycerides
run a new set of controls
27. If the correlation coefficient (r) of two variables is zero...
bilirubindiglucuronide
CK
porphobilinogen synthetase
there is an absence of correlation
28. The Henderson-Hasselbalch equation
HDL
viral hepatitis
pH = pKa + log (salt/acid)
freezing point
29. What specimen preparation is commonly used to perform the alkaline phosphatase isoenzyme determination?
100 nmol
serum aliquots - one heated
patient noncompliance
lead
30. A 21-year-old man with nausea - vomiting - and jaundice has the following laboratory findings: Total serum bilirubin level: 8.5 mg/dL (normal - 0-1.0) Conjugated serum bilirubin level: 6.1 mg/dL (normal - 0-0.5) Urine urobilinogen: Increased Fecal u
A1
chylomicrons VLDL
conjugated hyperbilirubinemia - hepatocellular obstruction
@ 100
31. Bile acid concentrations are useful to assess...
manic-depression
be able to detect 9/10 simple instrument malfunctions
hepatobiliary (obstruction?)
thyroxine
32. This condition does decrease activity of glucuronyl transferase result in increased unconjugated bilirubin and kernicterus in neonates
acute intermittent porphyria
lithium
testing heparinized plasma
crigler
33. The glucose level in normal peritoneal fluid should be...
BUN 80
the same as plasma glucose
HCT
turn off
34. A 9-month-old boy from Israel has gradually lost the ability to sit up and develops seizures. He has an increased amount of a phospholipid called GM2-ganglioside in his neurons - and he lacks the enzyme hexosaminidase A in his leukocytes. These findi
sodium
GLC
Tay-sachs
dirty electrodes
35. A 24-hour urine specimen (total volume = 1136 mL) is submitted to the laboratory for quantitative urine protein. Calculate the amount of protein excreted per day - if the total protein is 52 mg/dL.
591
A1c
porphyrin and porphobilinogen screen
Wilson's disease
36. In spectrophotometric determination - this is the formula for calculating the absorbance of a solution
absorptivity x light path x concentration
measure the total volume
chemical ionization matrix
have a negative charge
37. The anticonvulsant used to control tonic-clonic (grand mal) seizures is...
dirty electrodes
cmpds based on molecular weight and size
multiplied by 4
phenytoin
38. The definitive diagnosis of primary adrenal insufficiency requires demonstration of...
ceruplasmin
testing heparinized plasma
increased O2 decreased HCO3
impaired response to ACTH stimulation
39. A 45-year-old woman complains of fatigue - heat intolerance - and hair loss. Serum thyroxine and 125I-T3 resin uptake are abnormally low. What test would confirm that this is a pituitary deficiency?
<1%
90%
mg/ml
TSH
40. This enzyme substrates for prostatic acid phosphatase determination results in the highest specificity
thymolpthalein monophosphate
Hb S
atomic absorption
CO2
41. The different water content of erythrocytes and plasma makes true glucose concentrations in whole blood a function of the...
chloride
apoenzyme
dirty electrodes
HCT
42. Rickets is associated with deficiency of...
cysteine
inclusion of smokers and nonsmokers in the study population
increased vasoconstriction
D
43. As part of a hyperlipidemia screening program - the following results were obtained on a 25 year old woman 6 hours after eating:Triglycerides = 260 mg/dLCholesterol = 120 mg/dL - This is the BEST interpretation of these results?
cholesterol normal triglycerides elevated
cmpds based on molecular weight and size
200
whole blood can be used
44. Following overnight fasting - hypoglycemia in adults is defined as a glucose of...
cysteine
carbohydrate hyperalimentation
<45
coulometry
45. This wavelengths is within the ultraviolet rang.
340
quantitation of label
intestinal malabsorption
conjugated hyperbilirubinemia - hepatocellular obstruction
46. The formula for calculating absorbance given the percent transmittance (%T) of a solution
4.5
2-log(T)
coulometry
faster than gamma
47. A course of instruction is being planned to teach laboratory employees to correct simple malfunctions in selected laboratory instruments. In writing the objectives for this course - this would be most appropriate?
be able to detect 9/10 simple instrument malfunctions
parathyroid hormone
primary hyperparathyroidism
340
48. A patient has the following results: Patient Values : Reference Values: Serum iron 250 ug/dL 60-150 ug/dL TIBC 350 ug/dL 300-35O ug/dL The best conclusion is that this patient has...
C
iron hemochromatosis
HPLC analysis of porpobilinogen on 24hr urine
changes in the fuel
49. The osmolality of a urine or serum specimen is measured by a change in the...
freezing point
heparin
CO2
5mg higher
50. The main reason for suboptimal drug levels in therapeutic drug monitoring is...
inclusion of smokers and nonsmokers in the study population
patient noncompliance
increase in total circulating T4
elevated lactic acid - elevated pyruvate