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Chemistry Certification

Instructions:

Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can study here.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. The following laboratory results were obtained on arterial blood: Sodium 136 mEq/L pH 7.32 Potassium 4.4 mEq/L PCO2 79 mm Hg Chloride 92 mEq/L Bicarbonate 40 mEq/L These results are most compatible with...
respiratory acidosis
MI
nondiagnostic for MS
without a disease with a negative test result

2. This is a glycolytic enzyme that catalyzes the cleavage of fructose-1 - 6-diphosphate to glyceraldehyde-3-phosphate and dihydroxyacetone phosphate
fresh morning urine for delta-aminolevulinic acid
ionization of carboxyl groups (yielding a net negative charge)
accuracy
aldolase

3. The most specific enzyme test for acute pancreatitis is...
alpha 2 beta
viral hepatitis
lipase
biuret

4. Acidosis and alkalosis are best defined as fluctuations in blood pH and CO2 content due to changes in...
testosterone
LDL
bicarbonate buffer
C

5. The anticonvulsant used to control tonic-clonic (grand mal) seizures is...
21-hydroxylase deficiency
A1
one micromole/minute
phenytoin

6. The major fraction of organic iodine in the circulation is in the form of...
thyroxine
(testing of urine for) delta-am.. acid
faster than gamma
porphyrin and porphobilinogen screen

7. A breakdown product of hemoglobin is...
porphobilinigen SCREEN
measures one ion more than others
bilirubin
patient noncompliance

8. An acid cleaning solution for glassware consists of...
exposure to CO
potassium dichromate in SA
specificity
5mg higher

9. In developing the reference for a new EIA for CEA - the range for the normal population was broader than that published by the vendor. Controls are acceptable with a narrow coefficient of variation. This may be explained by...
glucose oxidase
2-log(T)
bicarbonate buffer
inclusion of smokers and nonsmokers in the study population

10. Cerebrospinal fluid for glucose assay should be...
analyzed immediately
iron deficiency anemia
diet
increase in total circulating T4

11. Stray light can be detected in a spectrophotometer by utilizing a...
sharp cutoff filter
acute hepatitis
thymolpthalein monophosphate
pH pCO2 pO2

12. A blood gas sample was sent to the lab on ice - and a bubble was present in the syringe. The blood had been exposed to room air for at least 30 minutes. The following change in blood gases occurred...
creatinine
porphobilinogen synthetase
0
pO2 increased HCO3 decreased

13. Serum concentrations of vitamin B12 are elevated in...
freezing point
increased vasoconstriction
1 micromole per minute
CML

14. Phenobarbital is a metabolite of...
heparin
primidone
cysteine
porphyrin and porphobilinogen screen

15. Specimens for blood gas determination should be drawn into a syringe containing...
heparin
tissue and serum levels need to reach equilibrium
multiplied by 4
pH pCO2 pO2

16. The function of the major lipid components of the very low density lipoproteins (VLDL) is to transport...
lactic acidosis
elevated lactic acid - elevated pyruvate
fetal and placenta function
endogenous triglycerides

17. A patient with glomerulonephritis would present the following serum results...
immunofixation
increase in total circulating T4
enzyme induction
BUN increased

18. After a difficult venipuncture requiring prolonged application of the tourniquet - the serum K+ was found to be 6.8 mEq/L. The best course of action is to...
enzyme immunoassay
oxalacetate to malate
cancel test
atomic absorption

19. A 45-year-old woman complains of fatigue - heat intolerance - and hair loss. Serum thyroxine and 125I-T3 resin uptake are abnormally low. What test would confirm that this is a pituitary deficiency?
LDL
transferrin
TSH
40-50

20. An electrode has a silver/silver chloride anode and a platinum wire cathode. It is suspended in KCl solution and separated from the blood to be analyzed by a selectively permeable membrane. Such an electrode is used to measure...
plasma bicarbonate
ratio of distance moved by solvent to distance moved by compound
NADH
O2

21. The expected blood gas results for a patient in chronic renal failure would match the pattern of...
90%
pilocarpine
metabolic acidosis
TSH

22. Diagnostic specificity is defined as the percentage of individuals...
fetal and placenta function
potassium dichromate in SA
100 nmol
WITHOUT a disease with a negative test

23. Technical problems encountered during the collection of an amniotic fluid specimen caused doubt as to whether the specimen was amniotic in origin. This procedure would establish that the fluid is amniotic in origin
<1%
multiplied by 4
agarose
creatinine

24. The formula for calculating serum osmolality that incorporates a correction for the water content of plasma is...
testing heparinized plasma
acute hepatitis
2Na + glucose over 20 + BUN over 3
GFR

25. The different water content of erythrocytes and plasma makes true glucose concentrations in whole blood a function of the...
hyperventilation
Tay-sachs
1 micromole per minute
HCT

26. A potentiometric electrode that measures an analyte that passes through a selectively premeable membrane and rapidly enters into an equilibrium with an electrolyte solution is...
plasma bicarbonate
pCO2
occult blood
run a new set of controls

27. One international unit of enzyme activity is the amount of enzyme that - under specified reaction conditions of substrate concentration - pH - and temperature - causes utilization of substrate at the rate of...
crigler
1.9
one micromole/minute
32

28. Diagnostic specificity is defined as the percentage of individuals...
without a disease with a negative test result
bicarbonate carbonic acid
200
A1

29. A pH of 7.0 represents a H+ concentration of...
peptide bonds
breast cancer
100nmol
glucose oxidase

30. Upon completion of a run of cholesterol tests - the technician recognizes that the controls are not within the two standard deviations confidence range. What is the appropriate course of action?
catalyze redox reactions
run a new set of controls
C
5

31. Gel filtration chromatography is used to separate...
respiratory acidosis
A1c
4.5
cmpds based on molecular weight and size

32. Kernicterus is an abnormal accumulation of bilirubin in...
1.9
brain
CK
lead

33. High levels of which lipoprotein class are associated with decreased risk of accelerated atherosclerosis?
iron deficiency anemia
conjugated hyperbilirubinemia - hepatocellular obstruction
L/S ratio > 3.5
HDL

34. This 2-hour postprandial glucose values demonstrates unequivocal hyperglycemia diagnostic for diabetes mellitus
plasma bicarbonate
65
20:1
200

35. This disease is associated with the greatest elevation of lactate dehydrogenase isoenzyme 1?
B12 deficiency
GFR
glucose oxidase
2Na + glucose over 20 + BUN over 3

36. The protein portion of an enzyme complex is called the...
200x affinity for oxygen
apoenzyme
2Na + glucose over 20 + BUN over 3
respiratory ACIDOSIS

37. In familial hypercholesterolemia - the hallmark finding is an elevation of...
LDL
sample exposed to light
accuracy
ammonia

38. A potassium level of 6.8 mEq/L is obtained. Before reporting the results - the first step the technologist should take is to...
increased O2 decreased HCO3
check serum for hemolysis
conjugated hyperbilirubinemia - hepatocellular obstruction
absorptivity x light path x concentration

39. A condition in which erythrocyte protoporphyrin is increased is...
iron deficiency anemia
properties of the membrane
iron hemochromatosis
porphobilinigen SCREEN

40. Upon development of a thin layer chromatogram for the drug analysis - all drug spots (including the standards) had migrated with the solvent front. The most probable cause for this would be...
incorrect aqueous to nonaqueous mixture
phenytoin
measurement of absorbance at 450
TSH

41. A cardiac glycoside that is used in the treatment of congenital heart failure and arrhythmias by increasing the force and velocity of myocardial contraction is...
digoxin
90%
exchange of amino and keto groups
respiratory acidosis

42. In the liver - bilirubin is converted to...
NADH
check serum for hemolysis
bilirubindiglucuronide
chemical ionization matrix

43. The following five sodium control values (mEq/L) were obtained:140 - 135 - 138 - 140 - 142Calculate the coefficient of variation.
1.9
HCT
20:1
correct for variations in flame and atomizer

44. A patient has the following results: Patient Values : Reference Values: Serum iron 250 ug/dL 60-150 ug/dL TIBC 350 ug/dL 300-35O ug/dL The best conclusion is that this patient has...
primidone
exposure to CO
iron hemochromatosis
binding capacity of thyroxine-binding globulin

45. In a normal individual - injection of thyrotropin-releasing hormone (TRH) causes an increase in blood concentrations of this hormone
crigler
alkaline picrate
Prolactin
measures one ion more than others

46. A blood gas sample was sent to the lab on ice - and a bubble was present in the syringe. The blood had been exposed to room air for at least 30 minutes. The following change in blood gases occurred...
Prolactin
analyzed immediately
band width
increased O2 decreased HCO3

47. The fast hemoglobin fraction is...
A1
analyzed immediately
1.9
lower than in adults

48. Coulometry is used to measure...
CML
apoenzyme
chloride
lead

49. Beriberi is associated with deficiency of...
multiplied by 4
thiamine
increased O2 decreased HCO3
21-hydroxylase deficiency

50. This method employs a highly specific antibody to thyroxine
CML
specimen exposure to light
correct for variations in light intensity
T4 by RIA