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Test your basic knowledge |
Chemistry Certification
Start Test
Study First
Subject
:
certifications
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. A 45-year-old woman complains of fatigue - heat intolerance - and hair loss. Serum thyroxine and 125I-T3 resin uptake are abnormally low. What test would confirm that this is a pituitary deficiency?
occult blood
can be used for absorbtion - partition - ion exchange - and gel permeation chromatography
TSH
growth - third trimester of pregnancy
2. A critically ill patient becomes comatose. The physician believes the coma is due to hepatic failure. The assay most helpful in this diagnosis is...
atomic absorption
iron deficiency anemia
ammonia
phenytoin
3. The most sensitive enzymatic indicator for liver damage from ethanol intake is...
mg/ml
freezing point
90%
GGT
4. Enzymes used in the diagnosis of acute pancreatitis?
amylase and lipase
thymolpthalein monophosphate
bilirubindiglucuronide
creatine kinase
5. A psychiatric patient was experiencing sever depression - but responded to treatment with amitriptyline with no apparent side effects. A blood sample was sent to the laboratory for therapeutic monitoring. Which drug level would be MOST reflective of
alkaline picrate
increased O2 decreased HCO3
amytriptyline 104
cyclic antidepressants
6. A 25-year-old man became nauseated and vomited 90 minutes after receiving a standard 75-g carbohydrate dose for an oral glucose tolerance test. The best course of action is...
fetal and placenta function
normal - liver breakdown
draw blood for glucose and discontinue test
pH = pKa + log (salt/acid)
7. The most widely used support medium for electrophoretic separation of lipoproteins is...
coulometry
show a decrease in glycosylated hgb
glass
agarose
8. This elevates carboxyhemoglobin?
9
cancel test
exposure to CO
spun separated iced and tested immediately
9. An HPLC operator notes that the column pressure is too high - is rising too rapidly - and the recorder output is not producing normal peaks. The most probable cause of the problem is...
glass
3500
peroxidase-like activity of hemoglobin
effluent line is obstructed
10. A fasting serum sample from an asymptomatic 43-year-old woman is examined visually chemically with the following results: Initial appearance of serum: Milky Appearance of serum after overnight refrigeration: Cream layer over turbid serum Triglyceri
chylomicrons VLDL
acute intermittent porphyria
C3 complement
cyclic antidepressants
11. A patient had the following serum results: Na+ 140 mEq/L K+ 4.0 mEq/L Glucose 95 mg/dL BUN 10 mg/dL Which osmolality is consistent with these results?
respiratory ACIDOSIS
270
acid phosphatase
increased O2 decreased HCO3
12. Upon completion of a run of cholesterol tests - the technician recognizes that the controls are not within the two standard deviations confidence range. What is the appropriate course of action
run a new set of controls
glucose
Solute moves half the distance of the solvent front
1:5
13. The first step in analyzing a 24-hour urine specimen for quantitative urine protein is...
correct for variations in flame and atomizer
measure the total volume
thyroxine
can be separated into distinct phenotypes
14. Quantitation of NA+ and K+ by ion-selective electrode is more rapid than flame photometry because...
whole blood can be used
GLC
tissue and serum levels need to reach equilibrium
aldolase
15. The following bilirubin results are obtained on a patient: Day 1: 4.3 mg/dL Day 4: 2.2 mg/dL Day 2: 4.6 mg/dL Day 5: 4.4 mg/dL Day 3: 4.5 mg/dL Day 6: 4.5 mg/dL - Given that the controls were within range each day - what is a probable explanation for
sample exposed to light
90%
F
specimen exposure to light
16. The regulation of calcium and phosphorus metabolism is accomplished by which gland?
parathyroid
Calcium - phosphorus
20:1
pH pCO2 pO2
17. On immunoassays using enzyme-labeled antibodies or antigens: ___________ can be carried out with a spectrophotometer
respiratory acidosis
carbs
D
quantitation of label
18. Most drugs and intracellular metabolites measured by radioimmunoassay have molecular weights between 200 and 1000 and can be made immunogenic by...
draw blood for glucose and discontinue test
attaching them to protein molecules
freezing point
have a negative charge
19. A blood sample was received from the emergency room with a request for narcotic analysis. The request slip indicated that the patient (a known heroin addict) responded to naloxone administration. The serum was negative for morphine by EIA. What other
2Na + glucose over 20 + BUN over 3
methadone
0
creatinine clearance
20. In familial hypercholesterolemia - the hallmark finding is an elevation of...
B12 deficiency
high carbohydrate diet for 3 days
LDL
standard
21. Nephelometers measure light...
scattered at a right angle
glass
wavelength
creatine kinase
22. The anion gap is useful for quality control of laboratory results for...
sodium potassium chloride CO2
atomic absorption
inhibitor binds to enzyme at same site as substrate
CO2 and pH elevated
23. An increase in serum acetone is indicative of a defect in the metabolism of...
faster than gamma
carbs
bone
growth - third trimester of pregnancy
24. This enzyme substrates for prostatic acid phosphatase determination results in the highest specificity
agarose
thymolpthalein monophosphate
cholesterol normal triglycerides elevated
electric current
25. A patient is admitted to the emergency room in a state of metabolic alkalosis.This would be consistent with this diagnosis?
C
high co2 and hco3
parathyroid
increased O2 decreased HCO3
26. While performing a serum lithium determination on a flame photometer with cesium as the internal standard - the technologist noticed that there was a flickering flame. The most probable cause of this problem is...
dirty electrodes
changes in the fuel
check serum for hemolysis
normal - liver breakdown
27. A course of instruction is being planned to teach laboratory employees to correct simple malfunctions in selected laboratory instruments. In writing the objectives for this course - this would be most appropriate?
be able to detect 9/10 simple instrument malfunctions
bicarbonate buffer
hyperventilation
90%
28. One international unit of enzyme activity is the amount of enzyme that - under specified reaction conditions of substrate concentration - pH - and temperature - causes utilization of substrate at the rate of...
benzoylecogine
(testing of urine for) delta-am.. acid
occult blood
one micromole/minute
29. A patient with malabsorption receives 25 g of d-xylose orally; during the subsequent 5-hour period - the urine excretion of d-xylose is less than 3 g. This would indicate...
intestinal malabsorption
Wilson's disease
acute hepatitis
Hb S
30. Scurvy is associated with deficiency of...
TSH
9
M subunit is inactivated
C
31. TSH is produced by the...
immunofixation
lipase
pituitary
peptide bonds
32. The chemical composition of HDL- cholesterol corresponds to...
amylase and lipase
spun separated iced and tested immediately
5 tri 15 cholesterol 50 protein
no ice clots bubbles
33. The first step to be taken when attempting to repair a piece of electronic equipment is...
B12 deficiency
high carbohydrate diet for 3 days
turn off
conjugated hyperbilirubinemia - hepatocellular obstruction
34. The greatest activities of serum AST and ALT are seen in...
ALP with fresh draw
correct for variations in light intensity
incorrect aqueous to nonaqueous mixture
acute hepatitis
35. The concentration of serum carotene is affected MOST by...
diet
fresh morning urine for delta-aminolevulinic acid
show a decrease in glycosylated hgb
correct for variations in light intensity
36. Gel filtration chromatography is used to separate...
HDL
cmpds based on molecular weight and size
endosmosis
oxalacetate to malate
37. A person suspected of having metabolic alkalosis would have these laboratory findings
porphobilinogen screen
100 nmol
CO2 and pH elevated
no decrease in serum growth hormone after 90 minutes
38. In electrophoresis of proteins - when the sample is placed in an electric field connected to a buffer of pH 8.6 - all of the proteins...
plasma bicarbonate
run a new set of controls
have a negative charge
a small concentration of APO-B containing lipoproteins after precipitation
39. This electrolyte is the chief plasma cation whose main function is maintaining osmotic pressure
sodium
sample exposed to light
HPLC analysis of porpobilinogen on 24hr urine
amylase
40. The general types of interference in atomic absorption spectrophotometry...
adding an acid stabilizer
chemical ionization matrix
nephelometry
freezing point
41. The TRH (thyrotropin-releasing hormone) stimulation test is useful in assessing...
hyperthyroidism
show a decrease in glycosylated hgb
serum cortisol > 15
fresh morning urine for delta-aminolevulinic acid
42. Thiis serum protein fraction is most likely to be elevated in patients with nephrotic syndrome?
binding capacity of thyroxine-binding globulin
T4 by RIA
show a decrease in glycosylated hgb
alpha 2 beta
43. The preparation of a patient for standard tolerance testing should include...
high carbohydrate diet for 3 days
attaching them to protein molecules
glucose tolerance test
faster than gamma
44. Detection of carriers of hereditary coproporphyria should include analysis of...
amytriptyline 104
occult blood
fresh morning urine for delta-aminolevulinic acid
90%
45. This diseases results from a familial absence of high-density lioprotein
Tangier
bicarbonate buffer
LDL
specificity
46. The following laboratory results were obtained on arterial blood: Sodium 136 mEq/L pH 7.32 Potassium 4.4 mEq/L PCO2 79 mm Hg Chloride 92 mEq/L Bicarbonate 40 mEq/L These results are most compatible with...
Temperature is a function of the number of particles in solution
respiratory acidosis
benzoylecogine
plasma bicarbonate
47. The buffering capacity of blood is maintained by a reversible exchange process between bicarbonate and...
5 tri 15 cholesterol 50 protein
CK-MB
chloride
be able to detect 9/10 simple instrument malfunctions
48. In respiratory acidosis - a compensatory mechanism is the increase in...
spun separated iced and tested immediately
normal - liver breakdown
plasma bicarbonate
g/MW
49. The most common type of congenital adrenal hyperplasia associated with increased plasma concentrations of 17 a-hydroxyprogesterone and increased urinary excretion of pregnanetriol is...
21-hydroxylase deficiency
1.9
manic-depression
glucose tolerance test
50. When taken by a euthyroid individual - oral contraceptives containing estrogens will have this effects on the thyroid function studies
porphobilinogen screen
increase in total circulating T4
TSH
1:5