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Test your basic knowledge |
Chemistry Certification
Start Test
Study First
Subject
:
certifications
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. The most consistent analytical error involved in the routine determination of HDLcholesterol is caused by...
a small concentration of APO-B containing lipoproteins after precipitation
340
para-hydroxylphenyl...
exchange of amino and keto groups
2. A 45-year-old woman complains of fatigue - heat intolerance - and hair loss. Serum thyroxine and 125I-T3 resin uptake are abnormally low. What test would confirm that this is a pituitary deficiency?
can be separated into distinct phenotypes
occult blood
albumin
TSH
3. Serum anion gap is increased in patients with...
lactic acidosis
acute intermittent porphyria
manic-depression
lead
4. A test request slip indicates that an acute porphyric attack is suspected clinically. Analysis should include...
porphobilinigen SCREEN
show a decrease in glycosylated hgb
exchange of amino and keto groups
9
5. Regan isoenzyme has the same properties as alkaline phosphatase that originates in the...
placenta
viral hepatitis
hyperventilation
HPLC analysis of porpobilinogen on 24hr urine
6. This disease is associated with the greatest elevation of lactate dehydrogenase isoenzyme 1?
CO2 and pH elevated
B12 deficiency
is quantitated by the amount of light produced
transferrin
7. A low concentrarion of serum phosphorus is commonly found in...
improving state of metabolic control (as indicated by fructosamine)
minimize the effects of interference
increased vasoconstriction
carbohydrate hyperalimentation
8. Blood specimens for digoxin assays should be obtained between 8 hours or more after drug administration because...
conjugated hyperbilirubinemia - hepatocellular obstruction
tissue and serum levels need to reach equilibrium
apoenzyme
immunofixation
9. Oligoclonal bands are present on electrophoresis of concentrated CSF and also on concurrently tested serum of the same patient. The proper interpretation is...
nondiagnostic for MS
128
GGT
porphobilinigen SCREEN
10. This enzymes catalyzes the conversion of starch to glucose and maltose
immunofixation
amylase
acute hepatitis
GLC
11. 4 mL of water is added to 1 mL of serum. This represents this serum dilutions
placenta
valine leucine isoleucine
1:5
sodium potassium chloride CO2
12. The major fraction of organic iodine in the circulation is in the form of...
increased vasoconstriction
inclusion of smokers and nonsmokers in the study population
thyroxine
the fetus is at risk for respiratory distress
13. The direction in which albumin migrates (ie - toward anode or cathode) during electrophoretic separation of serum proteins - at pH 8.6 - is determined by...
(testing of urine for) delta-am.. acid
nephelometry
hepatobiliary (obstruction?)
ionization of carboxyl groups (yielding a net negative charge)
14. A patient with hemolytic anemia will...
show a decrease in glycosylated hgb
heparin
have a negative charge
sharp cutoff filter
15. The methodology based on the amount of energy absorbed by a subtance as a function of its concentration and using a specific source of the same material as the substance analyzed is...
adding an acid stabilizer
atomic absorption
impaired response to ACTH stimulation
measures one ion more than others
16. Estrogen and progesterone receptor assays are useful in assessing prognosis in...?
increased vasoconstriction
glucose oxidase
SD over mean
breast cancer
17. After a difficult venipuncture requiring prolonged application of the tourniquet - the serum K+ was found to be 6.8 mEq/L. The best course of action is to...
TSH
increase in total circulating T4
viral hepatitis
cancel test
18. The following blood gas results were obtained: pH : 7.18 PO2: 86 mm Hg PCO2: 60 mm Hg O2 saturation: 92% HCO3-: 21 mEq/L TCO2: 23 mEq/L Base excess: -8.0 mEq/L The patient's results are compatible with...
CO2
run a new set of controls
thiamine
emphysema
19. The formula for calculating absorbance given the percent transmittance (%T) of a solution
2-log(T)
atomic absorption
LDL
thiamine
20. An automated CK assay gives a reading that is above the limits of linearity. A dilution of the serum sample is made by adding 1 mL of serum to 9 mL of water. The instrument now rew 350 U/L. The correct report on the undiluted serum should be...
<45
thiamine
3500
the same as plasma glucose
21. The most heat labile fraction of alkaline phosphatase is obtained from...
1.9
TLC
bone
impaired response to ACTH stimulation
22. The enzyme present in almost all tissues that may be separated by electrophoresis into five components is...
pH = pKa + log (salt/acid)
catalyze redox reactions
mg/ml
LDH
23. The anion gap is useful for quality control of laboratory results for...
iron deficiency anemia
pH = pKa + log (salt/acid)
sodium potassium chloride CO2
C3 complement
24. What substance gives feces its normal color?
D
urobilin
sharp cutoff filter
biuret
25. Gas chromatography with the nitrogen/phosphorus detector is the most commonly used technique for the analysis of...
porphobilinogen screen
chloride
cyclic antidepressants
amylase and lipase
26. Alkaline phosphatase Slight increase - Aminotransferase Marked increase - Aspartate aminotransferase Marked increase - Alanine gamma-glutamyl transferase Slight increase
L/S ratio > 3.5
acute hepatitis
pH = pKa + log (salt/acid)
inclusion of smokers and nonsmokers in the study population
27. A spectrophotometer is being considered for purchase by a small laboratory. This specification reflects the spectral purity of the instrument
band width
binding capacity of thyroxine-binding globulin
peroxidase-like activity of hemoglobin
acute hepatitis
28. A patient with myeloproliferative disorder has the following values: Hgb = 13 g/dL Hct = 38% WBC = 30 x 10^3/uL Platelets = 1000 x 10^3/uL Serum Na+ = 140 mEq/L Serum K+ = 7 mEq/L The serum K+ should be confirmed by...
dihydroxyacetone side chain
sharp fibrinogen peak
200
testing heparinized plasma
29. Magnesium carbonate is added in an iron binding capacity determination in order to...
peptide bonds
GGT
remove excess unbound iron
parathyroid
30. Clinical assays for tumor markers are the most important for...
methadone
C3 complement
BUN 80
monitoring the course of a known cancer
31. In respiratory acidosis - a compensatory mechanism is the increase in...
no decrease in serum growth hormone after 90 minutes
lithium
nephelometry
plasma bicarbonate
32. Total iron-binding capacity measures the serum iron transporting capacity of...
viral hepatitis
transferrin
diet
Tay-sachs
33. This enzyme substrates for prostatic acid phosphatase determination results in the highest specificity
the fetus is at risk for respiratory distress
inclusion of smokers and nonsmokers in the study population
thymolpthalein monophosphate
MI
34. In developing the reference for a new EIA for CEA - the range for the normal population was broader than that published by the vendor. Controls are acceptable with a narrow coefficient of variation. This may be explained by...
inclusion of smokers and nonsmokers in the study population
pH pCO2 pO2
impaired response to ACTH stimulation
prevent phosphate interference
35. This serum constituent is unstable if a blood specimen is left standing at room temperature for 8 hours before processing
ALP with fresh draw
glucose
acute hepatitis
urobilin
36. Most automated blood gas analyzers directly measure...
pH pCO2 pO2
band width
atomic absorption
plasma bicarbonate
37. Analysis of erythrocytes for uroporphyrinogen I synthetase detects...
GFR
acute intermittent porphyria
run a new set of controls
CO2
38. A patient is admitted with biliary cirrhosis. If a serum protein electrophoresis is preformed - these globulin fractions will be most elevated?
beta
primary hyperparathyroidism
5mg higher
correct for variations in light intensity
39. This chemical determination may be of help in establishing the presence of seminal fluid
faster than gamma
128
exchange of amino and keto groups
acid phosphatase
40. Pregnant women with symptoms of thirst - frequent urination - or unexplained weight loss should have this test performed?
impaired response to ACTH stimulation
lipase
120 minutes
glucose tolerance test
41. When taken by a euthyroid individual - oral contraceptives containing estrogens will have this effects on the thyroid function studies
urobilin
Tay-sachs
LDL
increase in total circulating T4
42. In monitoring glomerular function - this test has the highest sensitivity
carbs
cysteine
chylomicrons
creatinine clearance
43. This steroid is an adrenal cortical hormone
respiratory ACIDOSIS
the fetus is at risk for respiratory distress
corticosterone
high carbohydrate diet for 3 days
44. The formation of estriol in a pregnant woman is dependent on...
catalyze redox reactions
fetal and placenta function
lower than in adults
<45
45. The hemoglobin that is resistant to alkali (KOH) denaturation is...
primidone
F
200
dirty electrodes
46. The formula for calculating serum osmolality that incorporates a correction for the water content of plasma is...
5 tri 15 cholesterol 50 protein
serum cortisol > 15
biuret
2Na + glucose over 20 + BUN over 3
47. The main reason for suboptimal drug levels in therapeutic drug monitoring is...
ratio of distance moved by solvent to distance moved by compound
urinary free cortisol
prostate
patient noncompliance
48. Stray light can be detected in a spectrophotometer by utilizing a...
porphobilinogen screen
immunofixation
sharp cutoff filter
dihydroxyacetone side chain
49. In the Jaffe reaction - creatine reacts with...
glucose
O2
properties of the membrane
alkaline picrate
50. A 9-month-old boy from Israel has gradually lost the ability to sit up and develops seizures. He has an increased amount of a phospholipid called GM2-ganglioside in his neurons - and he lacks the enzyme hexosaminidase A in his leukocytes. These findi
<45
fraction absorbed into systemic circulation
Tay-sachs
increase in total circulating T4