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Chemistry Certification
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Subject
:
certifications
Instructions:
Answer 50 questions in 15 minutes.
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study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. When the exact concentration of the solute of a solution is known and is used to evaluate the concentration of an unknown solution - the known solution is...
Tay-sachs
high carbohydrate diet for 3 days
sodium
standard
2. In using ion-exchange chromatographicbmethods - falsely increased levels of Hgb A1c will be demonstrated in presence of...
Hb S
T4 by RIA
transferrin
whole blood can be used
3. A common cause of a falsely increased LD1 fraction of lactic dehydrogenase is...
hemolysis
emphysema
HCT
measures one ion more than others
4. A spectrophotometer is being considered for purchase by a small laboratory. This specification reflects the spectral purity of the instrument
GLC
increased vasoconstriction
band width
chylomicrons
5. While performing a serum lithium determination on a flame photometer with cesium as the internal standard - the technologist noticed that there was a flickering flame. The most probable cause of this problem is...
testing heparinized plasma
sodium
ceruplasmin
changes in the fuel
6. The protein portion of an enzyme complex is called the...
apoenzyme
1 mol/kg
no ice clots bubbles
carbs
7. Enzymes used in the diagnosis of acute pancreatitis?
amylase and lipase
urinary free cortisol
O2
low pH
8. Assay of transketolase activity in blood is used to detect deficiency of...
thiamine
crigler
run a new set of controls
5mg higher
9. When separating serum proteins by cellulose acetate electrophoresis using veronal buffer at pH 8.6 - beta globulin migrates...
run a new set of controls
carbohydrate hyperalimentation
faster than gamma
BUN increased
10. A test request slip indicates that an acute porphyric attack is suspected clinically. Analysis should include...
sodium
1.1
porphobilinigen SCREEN
inhibitor binds to enzyme at same site as substrate
11. Ion selective electrodes are called selective rather than specific because they actually measure the...
occult blood
measures one ion more than others
cancel test
albumin
12. This enzymes catalyzes the conversion of starch to glucose and maltose
TSH
no ice clots bubbles
amylase
patient noncompliance
13. The enzyme present in almost all tissues that may be separated by electrophoresis into five components is...
LDH
GGT
scattered at a right angle
pilocarpine
14. Measurement of total T4 by competitive protein binding or displacement is based on the specific binding properties of...
amylase
prostate
chloride
thyroxine binding globulin
15. This enzyme substrates for prostatic acid phosphatase determination results in the highest specificity
dirty electrodes
thymolpthalein monophosphate
<45
hemolysis
16. A fresh urine sample is received for "porphyrins" or "porphyria" without further information or specifications. Initial analysis should include...
prostate
porphyrin and porphobilinogen screen
low pH
lead
17. Serum from a patient with metastatic carcinoma of the prostate was separated from the clot and stored at room temperature. The following results were obtained: Patient Reference Range Calcium: 10.8 mg/dL 8.8-10.3 mg/dL LD:420 U/L 50-150 U/L Acid phos
ALP with fresh draw
CO2
L/S ratio > 3.5
prostate
18. In spectrophotometric determination - this is the formula for calculating the absorbance of a solution
20:1
absorptivity x light path x concentration
porphobilinogen synthetase
1 micromole per minute
19. Given the following results: Alkaline phosphatase Marked increase Aminotransferase Slight increase Aspartate aminotransferase Slight increase Alanine gamma-glutamyl transferase Marked increase This is most consistent with...
freezing point
CML
obstructive jaundice
Calcium - phosphorus
20. Amniotic fluid submitted for a lecithin/sphingomyelin (US) ratio has been left in a brown container since the night before. You would expect...
decreased lecithin
oxalacetate to malate
591
impaired response to ACTH stimulation
21. The hemoglobin that is resistant to alkali (KOH) denaturation is...
TSH
multiplied by 4
F
growth - third trimester of pregnancy
22. In the sweat test - the sweating stimulant is introduced to the skin by application of...
glycerol
run a new set of controls
electric current
endogenous triglycerides
23. A sweat chloride result of 55 mEq/L and a sweat sodium of 52 mEq/L were obtained ona patient who has a history of respiratory problems. The bestc interpretation of these results is...
have a negative charge
5
measures one ion more than others
boderline results test should be repeated
24. The method of choice for diagnosis of a protracted attack of porphyria is...
HPLC analysis of porpobilinogen on 24hr urine
Tay-sachs
F
TSH
25. Respiratory acidosis is described as a(n): ______ increase in CO2 decrease in pH
thyroxine binding globulin
ceruplasmin
9
glycerol
26. In electrophoresis of serum proteins - arifacts at the application point are most frequently caused by...
measurement of absorbance at 450
emphysema
dirty applicators
B12 deficiency
27. The osmolality of a urine or serum specimen is measured by a change in the...
remove excess unbound iron
cmpds based on molecular weight and size
freezing point
sharp cutoff filter
28. Zinc protoporphyrin or free erythrocyte protoporphyrin measurements are useful to assess blood concentrations of...
parathyroid
lead
Calcium - phosphorus
diet
29. The unit of measure for a standard solution is...
accuracy
mg/ml
albumin
chemical ionization matrix
30. The following laboratory results were obtained: Serum Calcium: Increased - Urine Calcium: Increased - Serum Phosphate: Decreased - Urine Phosphate: Increased Serum Alkaline Phosphatase: Normal or Increased These results are most compatible with...
primary hyperparathyroidism
creatinine clearance
parathyroid
testing heparinized plasma
31. The following blood gas results were obtained: pH : 7.18 PO2: 86 mm Hg PCO2: 60 mm Hg O2 saturation: 92% HCO3-: 21 mEq/L TCO2: 23 mEq/L Base excess: -8.0 mEq/L The patient's results are compatible with...
carbohydrate hyperalimentation
emphysema
effluent line is obstructed
A1c
32. The formation of estriol in a pregnant woman is dependent on...
32
glycerol
fetal and placenta function
TSH
33. If a drug has a half-life of 7 hours - how many doses given at 7-hour intervals does it usually take to achieve a steady state or plateau level?
5
TLC
conjugated hyperbilirubinemia - hepatocellular obstruction
diet
34. A patient had the following serum results: Na+ 140 mEq/L K+ 4.0 mEq/L Glucose 95 mg/dL BUN 10 mg/dL Which osmolality is consistent with these results?
occult blood
270
fall in pH - rise in pCO2
prevent phosphate interference
35. A blood sample was received from the emergency room with a request for narcotic analysis. The request slip indicated that the patient (a known heroin addict) responded to naloxone administration. The serum was negative for morphine by EIA. What other
BUN 80
properties of the membrane
parathyroid hormone
methadone
36. An emphysema patient suffering from fluid accumulation in the alveolar spaves is likely to be in what metabolic state?
measure the total volume
5 tri 15 cholesterol 50 protein
show a decrease in glycosylated hgb
respiratory ACIDOSIS
37. In a normal individual - injection of thyrotropin-releasing hormone (TRH) causes an increase in blood concentrations of this hormone
21-hydroxylase deficiency
128
is quantitated by the amount of light produced
Prolactin
38. Unless blood gas measurements are made immediately after sampling - in vitro glycolysis of the blood causes a...
fall in pH - rise in pCO2
CO2
testing heparinized plasma
multiplied by 4
39. Oligoclonal bands are present on electrophoresis of concentrated CSF and also on concurrently tested serum of the same patient. The proper interpretation is...
freezing point
cancel test
beta
nondiagnostic for MS
40. Hydrogen ion concentration (pH) in blood is usually determined by means of these electrodes?
turn off
faster than gamma
CO2
glass
41. What specimen preparation is commonly used to perform the alkaline phosphatase isoenzyme determination?
serum aliquots - one heated
freezing point
B12 deficiency
correct for variations in light intensity
42. The expected blood gas results for a patient in chronic renal failure would match the pattern of...
chloride
metabolic acidosis
thiamine
quantitation of label
43. After a difficult venipuncture requiring prolonged application of the tourniquet - the serum K+ was found to be 6.8 mEq/L. The best course of action is to...
HDL
brain
endogenous triglycerides
cancel test
44. In thin layer chromatography - the Rf value for a compound is given by the...
ratio of distance moved by solvent to distance moved by compound
ceruplasmin
Calcium - phosphorus
pH pCO2 pO2
45. The ability of a procedure to measure only the component(s) it claims to measure is called...
brain
LDL
specificity
5
46. This method employs a highly specific antibody to thyroxine
there is an absence of correlation
growth - third trimester of pregnancy
T4 by RIA
inhibitor binds to enzyme at same site as substrate
47. In competitive inhibition of an enzyme reaction the...
A1c
inhibitor binds to enzyme at same site as substrate
measure the total volume
parathyroid hormone
48. The stimulant that causes localized sweating for the sweat test is...
fall in pH - rise in pCO2
is quantitated by the amount of light produced
pilocarpine
mg/ml
49. Following overnight fasting - hypoglycemia in adults is defined as a glucose of...
hyperthyroidism
atomic absorption
<45
band width
50. A course of instruction is being planned to teach laboratory employees to correct simple malfunctions in selected laboratory instruments. In writing the objectives for this course - this would be most appropriate?
correct for variations in flame and atomizer
fraction absorbed into systemic circulation
bicarbonate buffer
be able to detect 9/10 simple instrument malfunctions
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