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Chemistry Certification

Instructions:

Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can study here.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. At blood pH 7.40 what is the ratio between bicarbonate and carbonic acid?
fraction absorbed into systemic circulation
viral hepatitis
20:1
270

2. Specimens for blood gas determination should be drawn into a syringe containing...
dihydroxyacetone side chain
heparin
TLC
electric current

3. In using ion-exchange chromatographicbmethods - falsely increased levels of Hgb A1c will be demonstrated in presence of...
1 mol/kg
mg/ml
Hb S
glass

4. In performing a spinal fluid protein determination - the specimen is diluted 1 part spinal fluid to 3 parts saline to obtain a result low enough to measure. To calculate the protein concentration the result must be...
multiplied by 4
conjugated hyperbilirubinemia - hepatocellular obstruction
fall in pH - rise in pCO2
4.5

5. Upon completion of a run of cholesterol tests - the technician recognizes that the controls are not within the two standard deviations confidence range. What is the appropriate course of action?
run a new set of controls
specificity
wavelength
L/S ratio > 3.5

6. The hemoglobin that is resistant to alkali (KOH) denaturation is...
enzyme immunoassay
measurement of absorbance at 450
C3 complement
F

7. Which percentage of total serum calcium is nondiffusible protein bound?
boderline results test should be repeated
40-50
128
turn off

8. Given the following results: Alkaline phosphatase Marked increase Aminotransferase Slight increase Aspartate aminotransferase Slight increase Alanine gamma-glutamyl transferase Marked increase This is most consistent with...
obstructive jaundice
120 minutes
HDL
nondiagnostic for MS

9. A patient is admitted to the emergency room in a state of metabolic alkalosis.This would be consistent with this diagnosis?
Tay-sachs
accuracy
fall in pH - rise in pCO2
high co2 and hco3

10. Detection of carriers of hereditary coproporphyria should include analysis of...
5 tri 15 cholesterol 50 protein
check serum for hemolysis
sample exposed to light
fresh morning urine for delta-aminolevulinic acid

11. This serum protein migrates with the beta-globulins on cellulose acetate at pH 8.6...
bilirubin
inclusion of smokers and nonsmokers in the study population
C3 complement
bilirubindiglucuronide

12. In the assay of lactate dehydrogenase - this product is actually measured
absorptivity x light path x concentration
NADH
lead
TSH

13. This wavelengths is within the ultraviolet rang.
acute hepatitis
acid phosphatase
heparin
340

14. Malic dehydrogenase is added to the aspartate aminotransaminase (AST) reaction to catalyze the conversion of...
act as carriers for ions
oxalacetate to malate
CK
dirty electrodes

15. The osmolality of a urine or serum specimen is measured by a change in the...
without a disease with a negative test result
freezing point
plasma bicarbonate
high co2 and hco3

16. A fasting serum sample from an asymptomatic 43-year-old woman is examined visually chemically with the following results: Initial appearance of serum: Milky Appearance of serum after overnight refrigeration: Cream layer over turbid serum Triglyceri
200x affinity for oxygen
chylomicrons VLDL
can be separated into distinct phenotypes
plasma bicarbonate

17. Serum anion gap is increased in patients with...
aldolase
32
inclusion of smokers and nonsmokers in the study population
lactic acidosis

18. Analysis of erythrocytes for uroporphyrinogen I synthetase detects...
manic-depression
porphobilinigen SCREEN
multiplied by 4
acute intermittent porphyria

19. Serum concentrations of vitamin B12 are elevated in...
increase in total circulating T4
CML
low pH
chylomicrons VLDL

20. A blood creatinine value of 5.0 mg/dL is most likely to be found with this blood value?
accuracy
BUN 80
quantitation of label
4.5

21. In spectrophotometric determination - this is the formula for calculating the absorbance of a solution
band width
absorptivity x light path x concentration
a small concentration of APO-B containing lipoproteins after precipitation
creatinine clearance

22. This electrolyte is the chief plasma cation whose main function is maintaining osmotic pressure
GGT
LDL
BUN increased
sodium

23. A patient had the following serum results: Na+ 140 mEq/L K+ 4.0 mEq/L Glucose 95 mg/dL BUN 10 mg/dL Which osmolality is consistent with these results?
placenta
run a new set of controls
patient noncompliance
270

24. A 45-year-old woman complains of fatigue - heat intolerance - and hair loss. Serum thyroxine and 125I-T3 resin uptake are abnormally low. What test would confirm that this is a pituitary deficiency?
TSH
Temperature is a function of the number of particles in solution
is quantitated by the amount of light produced
primidone

25. A serum potassium is 19.5 mg/100 mL. This value is equal to how many mEq/L (MW of K = 39)?
5
65
glucose oxidase
pCO2

26. The main reason for suboptimal drug levels in therapeutic drug monitoring is...
coulometry
5 tri 15 cholesterol 50 protein
Solute moves half the distance of the solvent front
patient noncompliance

27. An acid cleaning solution for glassware consists of...
potassium dichromate in SA
pCO2
prevent phosphate interference
100 nmol

28. Spectrophotometers isolate a narrow band pass by means of...
pH pCO2 pO2
cysteine
prisms and grating
respiratory ACIDOSIS

29. Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) are both elevated in this disease
a small concentration of APO-B containing lipoproteins after precipitation
nephelometry
viral hepatitis
dihydroxyacetone side chain

30. As part of a hyperlipidemia screening program - the following results were obtained on a 25 year old woman 6 hours after eating:Triglycerides = 260 mg/dLCholesterol = 120 mg/dL - This is the BEST interpretation of these results?
atomic absorption
triglycerides
cholesterol normal triglycerides elevated
270

31. In electrophoretic analysis - buffers...
lower than in adults
cholesterol normal triglycerides elevated
act as carriers for ions
aldolase

32. The enzyme that exists chiefly in skeletal muscle - heart - and brain; is grossly elevated in active muscular dystrophy; and rises early in myocardial infarction is...
fetal and placenta function
creatine kinase
pilocarpine
GFR

33. The following laboratory results were obtained on arterial blood: Sodium 136 mEq/L pH 7.32 Potassium 4.4 mEq/L PCO2 79 mm Hg Chloride 92 mEq/L Bicarbonate 40 mEq/L These results are most compatible with...
viral hepatitis
have a negative charge
diet
respiratory acidosis

34. The unit of measure for a standard solution is...
cmpds based on molecular weight and size
high carbohydrate diet for 3 days
mg/ml
faster than gamma

35. Before unconjugated bilirubin can react with Ehrlich's diazo reagent - this must be added
thymolpthalein monophosphate
bilirubin
methyl alcohol
attaching them to protein molecules

36. On immunoassays using enzyme-labeled antibodies or antigens: ___________ can be carried out with a spectrophotometer
WITHOUT a disease with a negative test
cmpds based on molecular weight and size
quantitation of label
LDH

37. The function of the major lipid components of the very low density lipoproteins (VLDL) is to transport...
respiratory acidosis
endogenous triglycerides
Wilson's disease
the same as plasma glucose

38. Cocaine is metabolized to...
benzoylecogine
conjugated hyperbilirubinemia - hepatocellular obstruction
serum aliquots - one heated
ALP with fresh draw

39. The general types of interference in atomic absorption spectrophotometry...
testing heparinized plasma
MI
chemical ionization matrix
transferrin

40. The reason carbon monoxide is so toxic is because it...
cyclic antidepressants
chloride
200x affinity for oxygen
trig

41. Calcium concentration in the serum is regulated by...
obstructive jaundice
scattered at a right angle
alkaline picrate
parathyroid hormone

42. Assay of transketolase activity in blood is used to detect deficiency of...
thiamine
acute hepatitis
(testing of urine for) delta-am.. acid
MI

43. In familial hypercholesterolemia - the hallmark finding is an elevation of...
draw blood for glucose and discontinue test
methyl alcohol
LDL
quantitation of label

44. This lipid results would be expected to be falsely elevated on a serum specimen from a nonfasting patient
placenta
patient noncompliance
trig
adding an acid stabilizer

45. When separating serum proteins by cellulose acetate electrophoresis using veronal buffer at pH 8.6 - beta globulin migrates...
<1%
faster than gamma
pilocarpine
M subunit is inactivated

46. What specimen preparation is commonly used to perform the alkaline phosphatase isoenzyme determination?
ratio of distance moved by solvent to distance moved by compound
maintain colloidal osmotic pressure
changes in the fuel
serum aliquots - one heated

47. Characteristic of the Bence Jones protein that is used to distinguish it from other urinary proteins is its solubility...
acid phosphatase
@ 100
sodium potassium chloride CO2
1 mol/kg

48. The concentration of serum carotene is affected MOST by...
diet
atomic absorption
1:5
lipase

49. One means of checking a spectrophotometer wavelength calibration in the visible range is by using a...
bone
enzyme induction
didymium filter
glucose oxidase

50. The formula for calculating absorbance given the percent transmittance (%T) of a solution
glycerol
ALP with fresh draw
2-log(T)
lithium