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Test your basic knowledge |
Chemistry Certification
Start Test
Study First
Subject
:
certifications
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. In electrophoresis of serum proteins - arifacts at the application point are most frequently caused by...
corticosterone
dirty applicators
elevated lactic acid - elevated pyruvate
exposure to CO
2. Amniotic fluid submitted for a lecithin/sphingomyelin (US) ratio has been left in a brown container since the night before. You would expect...
intestinal malabsorption
urinary free cortisol
decreased lecithin
band width
3. The most important buffer pair in plasma is the...
obstructive jaundice
placenta
D
bicarbonate carbonic acid
4. The definitive diagnosis of primary adrenal insufficiency requires demonstration of...
hyperventilation
270
increased O2 decreased HCO3
impaired response to ACTH stimulation
5. A serum potassium is 19.5 mg/100 mL. This value is equal to how many mEq/L (MW of K = 39)?
potassium dichromate in SA
cysteine
5
hyperventilation
6. The glucose level in normal peritoneal fluid should be...
spun separated iced and tested immediately
be able to detect 9/10 simple instrument malfunctions
the same as plasma glucose
elevated lactic acid - elevated pyruvate
7. The concentration of serum carotene is affected MOST by...
M subunit is inactivated
BUN increased
diet
creatine kinase
8. This applies to cryoscopic osmometry
acute hepatitis
TSH
standard
Temperature is a function of the number of particles in solution
9. Diagnostic specificity is defined as the percentage of individuals...
WITHOUT a disease with a negative test
glycerol
testosterone
5
10. Assay of transketolase activity in blood is used to detect deficiency of...
tissue and serum levels need to reach equilibrium
thiamine
bone
B12 deficiency
11. The function of the major lipid components of the very low density lipoproteins (VLDL) is to transport...
endogenous triglycerides
methyl alcohol
40-50
Calcium - phosphorus
12. Four children are admitted with malaise - anorexia - and abdominal pain. Further evaluations reveal mild anemia - erythrocyte basophilic stippling - and profound pica habits. Poisoning by which heavy metal is most likely responsible?
attaching them to protein molecules
analyzed immediately
lead
pO2 increased HCO3 decreased
13. An electrophoretic separation of lactate dehydrogenase isoenzymes that demonstrates an elevation in LD-l and LD-2 in a "flipped" pattern is consistent with...
parathyroid hormone
MI
run a new set of controls
CO2 and pH elevated
14. A patient has signs and symptoms suggestive of acromegaly. The diagnosis would be confirmed if the patient had...
breast cancer
no decrease in serum growth hormone after 90 minutes
intestinal malabsorption
cysteine
15. A breakdown product of hemoglobin is...
(testing of urine for) delta-am.. acid
immunofixation
LDL
bilirubin
16. The identification of Bence Jones protein is best accomplished by...
heparin
fetal and placenta function
immunofixation
3500
17. Fluctuation of the needle on a coulometric type titrator is most probably due to...
dirty electrodes
attaching them to protein molecules
immunofixation
carbs
18. The most common type of congenital adrenal hyperplasia associated with increased plasma concentrations of 17 a-hydroxyprogesterone and increased urinary excretion of pregnanetriol is...
dirty applicators
atomic absorption
21-hydroxylase deficiency
metabolic acidosis
19. In performing a spinal fluid protein determination - the specimen is diluted 1 part spinal fluid to 3 parts saline to obtain a result low enough to measure. To calculate the protein concentration the result must be...
CO2 and pH elevated
corticosterone
multiplied by 4
obstructive jaundice
20. A test request slip indicates that an acute porphyric attack is suspected clinically. Analysis should include...
endogenous triglycerides
elevated lactic acid - elevated pyruvate
lead
porphobilinigen SCREEN
21. An electrode has a silver/silver chloride anode and a platinum wire cathode. It is suspended in KCl solution and separated from the blood to be analyzed by a selectively permeable membrane. Such an electrode is used to measure...
can be used for absorbtion - partition - ion exchange - and gel permeation chromatography
O2
sharp cutoff filter
thyroxine binding globulin
22. A common cause of a falsely increased LD1 fraction of lactic dehydrogenase is...
hemolysis
emphysema
increased vasoconstriction
SD over mean
23. The normal concentration of proteins in cerebrospinal fluid - relative to serum protein - is...
<1%
bicarbonate buffer
specimen exposure to light
dihydroxyacetone side chain
24. High levels of which lipoprotein class are associated with decreased risk of accelerated atherosclerosis?
catalyze redox reactions
attaching them to protein molecules
HDL
electric current
25. The unit of measure for a standard solution is...
albumin
mg/ml
amytriptyline 104
TLC
26. The hemoglobin that is resistant to alkali (KOH) denaturation is...
F
phenytoin
peroxidase-like activity of hemoglobin
hyperventilation
27. This is a regulatory hormone.
enzyme immunoassay
parathyroid hormone
HCT
ceruplasmin
28. These enzymes of heme biosynthesis are inhibited by lead
bilirubin
porphobilinogen synthetase
mg/ml
agarose
29. When separating serum proteins by cellulose acetate electrophoresis using veronal buffer at pH 8.6 - beta globulin migrates...
Temperature is a function of the number of particles in solution
Tay-sachs
faster than gamma
prostate
30. The presence of this isoenzymes indicates acute myocardial damage
obstructive jaundice
agarose
there is an absence of correlation
CK-MB
31. Currently the most common method for specific identification and quantitation of serum barbiturates is...
crigler
GLC
inhibitor binds to enzyme at same site as substrate
methadone
32. This electrolyte is the chief plasma cation whose main function is maintaining osmotic pressure
sodium
lactic acidosis
@ 100
parathyroid
33. The formula for calculating serum osmolality that incorporates a correction for the water content of plasma is...
LDL
5mg higher
2Na + glucose over 20 + BUN over 3
amylase
34. Bile acid concentrations are useful to assess...
hepatobiliary (obstruction?)
fresh morning urine for delta-aminolevulinic acid
porphobilinogen synthetase
coulometry
35. A patient is admitted to the emergency room in a state of metabolic alkalosis.This would be consistent with this diagnosis?
hepatobiliary (obstruction?)
high co2 and hco3
boderline results test should be repeated
one micromole/minute
36. A chemiluminescent EIA...
GLC
200
iron deficiency anemia
is quantitated by the amount of light produced
37. Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) are both elevated in this disease
prisms and grating
multiplied by 4
Temperature is a function of the number of particles in solution
viral hepatitis
38. Patients with Cushing's syndrome exhibit...
exchange of amino and keto groups
21-hydroxylase deficiency
electric current
serum cortisol > 15
39. The nanometer is a measurement of...
hyperventilation
hemolysis
wavelength
absorptivity x light path x concentration
40. The selectivity of an ion-selective electrode is determined by the...
growth - third trimester of pregnancy
minimize the effects of interference
properties of the membrane
NADH
41. The following data were obtained from a cellulose acetate protein electrophoresis scan: Albumin area 75 units Gamma globulin area 30 units Total area 180 units Total protein 6.5 g/dL The gamma globulin content in g/dL is...
catalyze redox reactions
apoenzyme
serum cortisol > 15
1.1
42. The stimulant that causes localized sweating for the sweat test is...
maintain colloidal osmotic pressure
LDL
dirty applicators
pilocarpine
43. A common cause of respiratory alkalosis is...
pituitary
primidone
hyperventilation
tissue and serum levels need to reach equilibrium
44. The electrophoretic pattern of a plasma sample compared with a serum sample shows a...
can be separated into distinct phenotypes
creatine kinase
sharp fibrinogen peak
TSH
45. In respiratory acidosis - a compensatory mechanism is the increase in...
plasma bicarbonate
agarose
hemolysis
monitoring the course of a known cancer
46. The Henderson-Hasselbalch equation
a small concentration of APO-B containing lipoproteins after precipitation
pH = pKa + log (salt/acid)
freezing point
accuracy
47. In the atomic absorption method for calcium - lanthanum is used...
mg/ml
O2
glucose oxidase
prevent phosphate interference
48. Cerebrospinal fluid for glucose assay should be...
CO2 and pH elevated
90%
analyzed immediately
bone
49. The following laboratory results were obtained: Serum Calcium: Increased - Urine Calcium: Increased - Serum Phosphate: Decreased - Urine Phosphate: Increased Serum Alkaline Phosphatase: Normal or Increased These results are most compatible with...
340
hyperventilation
primary hyperparathyroidism
biuret
50. A 9-month-old boy from Israel has gradually lost the ability to sit up and develops seizures. He has an increased amount of a phospholipid called GM2-ganglioside in his neurons - and he lacks the enzyme hexosaminidase A in his leukocytes. These findi
freezing point
increased O2 decreased HCO3
monitoring the course of a known cancer
Tay-sachs