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Test your basic knowledge |
Chemistry Certification
Start Test
Study First
Subject
:
certifications
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Cerebrospinal fluid for glucose assay should be...
analyzed immediately
creatine kinase
C
WITHOUT a disease with a negative test
2. The buffering capacity of blood is maintained by a reversible exchange process between bicarbonate and...
LDL
chloride
apoenzyme
Tangier
3. Amniotic fluid submitted for a lecithin/sphingomyelin (US) ratio has been left in a brown container since the night before. You would expect...
decreased lecithin
coulometry
can be used for absorbtion - partition - ion exchange - and gel permeation chromatography
viral hepatitis
4. Alkaline phosphatase Slight increase - Aminotransferase Marked increase - Aspartate aminotransferase Marked increase - Alanine gamma-glutamyl transferase Slight increase
acute hepatitis
high carbohydrate diet for 3 days
LDH
5
5. A patient with hemolytic anemia will...
show a decrease in glycosylated hgb
O2
4.5
incorrect aqueous to nonaqueous mixture
6. The most sensitive enzymatic indicator for liver damage from ethanol intake is...
glucose tolerance test
sodium potassium chloride CO2
GGT
thyroxine
7. The Henderson-Hasselbalch equation
fresh morning urine for delta-aminolevulinic acid
pH = pKa + log (salt/acid)
endosmosis
fraction absorbed into systemic circulation
8. The most consistent analytical error involved in the routine determination of HDLcholesterol is caused by...
manic-depression
can be separated into distinct phenotypes
a small concentration of APO-B containing lipoproteins after precipitation
binding capacity of thyroxine-binding globulin
9. After a difficult venipuncture requiring prolonged application of the tourniquet - the serum K+ was found to be 6.8 mEq/L. The best course of action is to...
cancel test
sodium potassium chloride CO2
ALP with fresh draw
properties of the membrane
10. This hemoglobin has glucose-6-phosphate on the amino-terminal valine of the beta chain?
valine leucine isoleucine
BUN increased
A1c
specificity
11. The Porter-Silber method (phenylhydrazine in alcohol and sulfuric acid) involves which part of the steroid molecule?
dihydroxyacetone side chain
porphobilinogen screen
lead
oxalacetate to malate
12. A serum potassium is 19.5 mg/100 mL. This value is equal to how many mEq/L (MW of K = 39)?
5
0
analyzed immediately
decreased lecithin
13. A one MOLAL solution is equivalent to...
Tay-sachs
1 mol/kg
hemolysis
1:5
14. The primary function of serum albumin in the peripheral blood is to...
maintain colloidal osmotic pressure
remove excess unbound iron
200x affinity for oxygen
pO2 increased HCO3 decreased
15. In amniotic fluid - the procedure used to detect Rh isosensitization is...
high co2 and hco3
glycerol
measurement of absorbance at 450
thymolpthalein monophosphate
16. Enzymes used in the diagnosis of acute pancreatitis?
amylase and lipase
200x affinity for oxygen
run a new set of controls
normal - liver breakdown
17. Measurement of the serum acid phosphatase is used to detect neoplastic disease of the...
improving state of metabolic control (as indicated by fructosamine)
<45
bone
prostate
18. Serum levels that define hypoglycemia in preterm or low birth weight infants are...
@ 100
increase in total circulating T4
lower than in adults
ionization of carboxyl groups (yielding a net negative charge)
19. The most widely employed screening technique for drug abuse is...
phenytoin
specificity
TLC
apoenzyme
20. Clinical assays for tumor markers are the most important for...
monitoring the course of a known cancer
porphobilinogen screen
ALP with fresh draw
A1c
21. Serum and urine copper levels are assayed on a hospital patient with the following results: Patient Serum Cu: 58 ug/dL; Reference Value:70-140 ug/dL Patient Urine Cu: 83 ug/dL ; Reference Value: < 40 ug/dL This is most consistent with...
22. Diagnostic specificity is defined as the percentage of individuals...
conjugated hyperbilirubinemia - hepatocellular obstruction
ionization of carboxyl groups (yielding a net negative charge)
g/MW
WITHOUT a disease with a negative test
23. The identification of Bence Jones protein is best accomplished by...
oxalacetate to malate
immunofixation
parathyroid
minimize the effects of interference
24. This method offers the greatest sensitivity for HBsAg testing
5
oxalacetate to malate
adding an acid stabilizer
enzyme immunoassay
25. A fasting serum sample from an asymptomatic 43-year-old woman is examined visually chemically with the following results: Initial appearance of serum: Milky Appearance of serum after overnight refrigeration: Cream layer over turbid serum Triglyceri
chylomicrons VLDL
amytriptyline 104
multiplied by 4
cancel test
26. A breakdown product of hemoglobin is...
bilirubin
40-50
sample exposed to light
parathyroid
27. The principle of the occult blood test depends on the...
peroxidase-like activity of hemoglobin
prisms and grating
lipase
minimize the effects of interference
28. This enzymes catalyzes the conversion of starch to glucose and maltose
amylase
chloride
cysteine
a small concentration of APO-B containing lipoproteins after precipitation
29. This steroid is an adrenal cortical hormone
acute hepatitis
corticosterone
primidone
Solute moves half the distance of the solvent front
30. Four children are admitted with malaise - anorexia - and abdominal pain. Further evaluations reveal mild anemia - erythrocyte basophilic stippling - and profound pica habits. Poisoning by which heavy metal is most likely responsible?
carbohydrate hyperalimentation
inclusion of smokers and nonsmokers in the study population
mg/ml
lead
31. This serum constituent is unstable if a blood specimen is left standing at room temperature for 8 hours before processing
glucose
methyl alcohol
parathyroid hormone
alpha 2 beta
32. One international unit of enzyme activity is the amount of enzyme that - under specified reaction conditions of substrate concentration - pH - and temperature - causes utilization of substrate at the rate of...
one micromole/minute
ionic charge
Hb S
lead
33. In competitive inhibition of an enzyme reaction the...
270
biuret
iron hemochromatosis
inhibitor binds to enzyme at same site as substrate
34. Magnesium carbonate is added in an iron binding capacity determination in order to...
L/S ratio > 3.5
atomic absorption
remove excess unbound iron
the fetus is at risk for respiratory distress
35. The following results were obtained in a creatinine clearance evaluation: Urine concentration 84 mg/dL Urine volume 1440 mL/24 hr Serum concentration 1.4 mg/dL Body surface area 1.60 m2 (average = 1.73 m2) The creatinine cle~trance in mL/min is...
maintain colloidal osmotic pressure
65
acute hepatitis
32
36. To ensure an accurate ammonia level result - the specimen should be...
spun separated iced and tested immediately
1 micromole per minute
fraction absorbed into systemic circulation
accuracy
37. The T3 resin uptake test is a measure of...
dihydroxyacetone side chain
serum cortisol > 15
Wilson's disease
binding capacity of thyroxine-binding globulin
38. The TRH (thyrotropin-releasing hormone) stimulation test is useful in assessing...
dihydroxyacetone side chain
incorrect aqueous to nonaqueous mixture
creatine kinase
hyperthyroidism
39. On immunoassays using enzyme-labeled antibodies or antigens: ___________ can be carried out with a spectrophotometer
quantitation of label
inhibitor binds to enzyme at same site as substrate
triglycerides
100nmol
40. A patient had the following serum results: Na+ 140 mEq/L K+ 4.0 mEq/L Glucose 95 mg/dL BUN 10 mg/dL Which osmolality is consistent with these results?
<1%
2Na + glucose over 20 + BUN over 3
viral hepatitis
270
41. A 45-year-old woman complains of fatigue - heat intolerance - and hair loss. Serum thyroxine and 125I-T3 resin uptake are abnormally low. What test would confirm that this is a pituitary deficiency?
coulometry
TSH
SD over mean
benzoylecogine
42. Serum haptoglobin...
enzyme immunoassay
can be separated into distinct phenotypes
primidone
serum aliquots - one heated
43. The glucose level in normal peritoneal fluid should be...
specificity
BUN increased
Solute moves half the distance of the solvent front
the same as plasma glucose
44. The most important buffer pair in plasma is the...
sample exposed to light
wavelength
amylase and lipase
bicarbonate carbonic acid
45. The electrophoretic pattern of a plasma sample compared with a serum sample shows a...
without a disease with a negative test result
a small concentration of APO-B containing lipoproteins after precipitation
LDL
sharp fibrinogen peak
46. Bile acid concentrations are useful to assess...
turn off
100nmol
Prolactin
hepatobiliary (obstruction?)
47. Unless blood gas measurements are made immediately after sampling - in vitro glycolysis of the blood causes a...
LDH
fall in pH - rise in pCO2
128
<45
48. Regan isoenzyme has the same properties as alkaline phosphatase that originates in the...
specificity
oxalacetate to malate
placenta
thiamine
49. The expected blood gas results for a patient in chronic renal failure would match the pattern of...
metabolic acidosis
digoxin
Prolactin
plasma bicarbonate
50. Ninety percent of the copper present in plasma is bound to...
chloride
ceruplasmin
chloride
GGT