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Test your basic knowledge |
Chemistry Certification
Start Test
Study First
Subject
:
certifications
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Serum concentrations of vitamin B12 are elevated in...
CML
digoxin
Tay-sachs
200
2. A patient is admitted with biliary cirrhosis. If a serum protein electrophoresis is preformed - these globulin fractions will be most elevated?
specificity
parathyroid
beta
placenta
3. A serum sample was assayed for bilirubin at 10 AM and the result was 12 mg/dL. The same sample was retested at 3 PM. The result now is 8 mg/dL. The most likely explanation for this discrepancy is...
LDH
sodium
volumetric flask
sample exposed to light
4. At a pH of 8.6 the gamma globulins move toward the cathode - despite the fact that they are negatively charged. What is this phenomenon called?
endogenous triglycerides
emphysema
LDL
endosmosis
5. The buffer pH most effective at allowing amphoteric proteins to migrate toward the cathode in an electrophoretic system would be...
patient noncompliance
turn off
4.5
increased vasoconstriction
6. The osmolality of a urine or serum specimen is measured by a change in the...
high co2 and hco3
run a new set of controls
freezing point
20:1
7. An Rf value of 0.5 in thin-layer chromatography means...
tissue and serum levels need to reach equilibrium
bilirubindiglucuronide
exchange of amino and keto groups
Solute moves half the distance of the solvent front
8. The chemical composition of HDL- cholesterol corresponds to...
biuret
atomic absorption
multiplied by 4
5 tri 15 cholesterol 50 protein
9. Most most likely to be ordered in addition to serum calcium to determine the cause of tetany?
oxalacetate to malate
primary hyperparathyroidism
lower than in adults
Mg
10. A low concentrarion of serum phosphorus is commonly found in...
cholesterol normal triglycerides elevated
carbohydrate hyperalimentation
g/MW
2-log(T)
11. Four children are admitted with malaise - anorexia - and abdominal pain. Further evaluations reveal mild anemia - erythrocyte basophilic stippling - and profound pica habits. Poisoning by which heavy metal is most likely responsible?
a small concentration of APO-B containing lipoproteins after precipitation
TSH
lead
methyl alcohol
12. An increase in serum acetone is indicative of a defect in the metabolism of...
carbs
emphysema
endogenous triglycerides
lead
13. A patient has the following results: Patient Values : Reference Values: Serum iron 250 ug/dL 60-150 ug/dL TIBC 350 ug/dL 300-35O ug/dL The best conclusion is that this patient has...
monitoring the course of a known cancer
agarose
freezing point
iron hemochromatosis
14. The following laboratory results were obtained on arterial blood: Sodium 136 mEq/L pH 7.32 Potassium 4.4 mEq/L PCO2 79 mm Hg Chloride 92 mEq/L Bicarbonate 40 mEq/L These results are most compatible with...
increased vasoconstriction
spun separated iced and tested immediately
respiratory acidosis
faster than gamma
15. The preparation of a patient for standard tolerance testing should include...
aldolase
potassium dichromate in SA
high carbohydrate diet for 3 days
2-log(T)
16. An automated method for measuring chloride that generates silver ions in the reaction is...
coulometry
Tay-sachs
iron deficiency anemia
ceruplasmin
17. Isoenzyme assays are preformed to improve...
thyroxine
lower than in adults
specificity
bone
18. The serum glucose concentration of a diabetic patient undergoing a 2-hour glucose tolerance test should return to the baseline (fasting level) after a minimum of...
immunofixation
effluent line is obstructed
120 minutes
iron deficiency anemia
19. A blood sample was received from the emergency room with a request for narcotic analysis. The request slip indicated that the patient (a known heroin addict) responded to naloxone administration. The serum was negative for morphine by EIA. What other
urobilin
methadone
increased O2 decreased HCO3
Tay-sachs
20. The anticonvulsant used to control tonic-clonic (grand mal) seizures is...
phenytoin
measures one ion more than others
TSH
3500
21. Magnesium carbonate is added in an iron binding capacity determination in order to...
chylomicrons
remove excess unbound iron
LDH
can be used for absorbtion - partition - ion exchange - and gel permeation chromatography
22. An acid cleaning solution for glassware consists of...
measurement of absorbance at 450
para-hydroxylphenyl...
potassium dichromate in SA
patient noncompliance
23. In the liver - bilirubin is converted to...
measures one ion more than others
boderline results test should be repeated
bilirubindiglucuronide
peptide bonds
24. Following overnight fasting - hypoglycemia in adults is defined as a glucose of...
T4 by RIA
<45
591
absorptivity x light path x concentration
25. A critically ill patient becomes comatose. The physician believes the coma is due to hepatic failure. The assay most helpful in this diagnosis is...
pituitary
have a negative charge
ammonia
F
26. One international unit of enzyme activity is the amount of enzyme that - under specified reaction conditions of substrate concentration - pH - and temperature - causes utilization of substrate at the rate of...
fall in pH - rise in pCO2
nephelometry
TSH
1 micromole per minute
27. This serum constituent is unstable if a blood specimen is left standing at room temperature for 8 hours before processing
glucose
accuracy
nondiagnostic for MS
immunofixation
28. Certain enzymes are activated to metabolize drugs as a result of another drug action. This is referred to as...
enzyme induction
spun separated iced and tested immediately
5
CML
29. Malic dehydrogenase is added to the aspartate aminotransaminase (AST) reaction to catalyze the conversion of...
O2
oxalacetate to malate
Hb S
cyclic antidepressants
30. The most widely employed screening technique for drug abuse is...
sharp cutoff filter
correct for variations in flame and atomizer
TLC
CO2
31. When separating serum proteins by cellulose acetate electrophoresis using veronal buffer at pH 8.6 - beta globulin migrates...
ionic charge
elevated lactic acid - elevated pyruvate
faster than gamma
catalyze redox reactions
32. A patient has signs and symptoms suggestive of acromegaly. The diagnosis would be confirmed if the patient had...
no decrease in serum growth hormone after 90 minutes
serum aliquots - one heated
carbohydrate hyperalimentation
draw blood for glucose and discontinue test
33. Spectrophotometers isolate a narrow band pass by means of...
2-log(T)
pilocarpine
90%
prisms and grating
34. Patients with Cushing's syndrome exhibit...
benzoylecogine
serum cortisol > 15
amylase and lipase
properties of the membrane
35. When taken by a euthyroid individual - oral contraceptives containing estrogens will have this effects on the thyroid function studies
digoxin
endogenous triglycerides
128
increase in total circulating T4
36. A 9-month-old boy from Israel has gradually lost the ability to sit up and develops seizures. He has an increased amount of a phospholipid called GM2-ganglioside in his neurons - and he lacks the enzyme hexosaminidase A in his leukocytes. These findi
hemolysis
Tay-sachs
can be separated into distinct phenotypes
remove excess unbound iron
37. If a drug has a half-life of 7 hours - how many doses given at 7-hour intervals does it usually take to achieve a steady state or plateau level?
100nmol
cysteine
5
0
38. A test request slip indicates that an acute porphyric attack is suspected clinically. Analysis should include...
LDH
bilirubindiglucuronide
pH = pKa + log (salt/acid)
porphobilinigen SCREEN
39. Diagnostic specificity is defined as the percentage of individuals...
multiplied by 4
acute hepatitis
128
without a disease with a negative test result
40. When the exact concentration of the solute of a solution is known and is used to evaluate the concentration of an unknown solution - the known solution is...
respiratory ACIDOSIS
elevated lactic acid - elevated pyruvate
standard
triglycerides
41. A stool specimen that appears black and tarry should be tested for the presence of...
sodium
iron hemochromatosis
occult blood
digoxin
42. In developing the reference for a new EIA for CEA - the range for the normal population was broader than that published by the vendor. Controls are acceptable with a narrow coefficient of variation. This may be explained by...
inclusion of smokers and nonsmokers in the study population
decreased lecithin
act as carriers for ions
200
43. A 21-year-old man with nausea - vomiting - and jaundice has the following laboratory findings: Total serum bilirubin level: 8.5 mg/dL (normal - 0-1.0) Conjugated serum bilirubin level: 6.1 mg/dL (normal - 0-0.5) Urine urobilinogen: Increased Fecal u
21-hydroxylase deficiency
thymolpthalein monophosphate
conjugated hyperbilirubinemia - hepatocellular obstruction
1:5
44. Quantitation of NA+ and K+ by ion-selective electrode is more rapid than flame photometry because...
whole blood can be used
measure the total volume
exposure to CO
triglycerides
45. In electrophoresis of serum proteins - arifacts at the application point are most frequently caused by...
dirty applicators
carbohydrate hyperalimentation
exposure to CO
BUN increased
46. While performing a serum lithium determination on a flame photometer with cesium as the internal standard - the technologist noticed that there was a flickering flame. The most probable cause of this problem is...
changes in the fuel
creatine kinase
measurement of absorbance at 450
ceruplasmin
47. The hemoglobin that is resistant to alkali (KOH) denaturation is...
carbs
F
exposure to CO
standard
48. This chemical determination may be of help in establishing the presence of seminal fluid
acid phosphatase
120 minutes
GGT
have a negative charge
49. A common cause of a falsely increased LD1 fraction of lactic dehydrogenase is...
prisms and grating
hemolysis
1 micromole per minute
occult blood
50. Oligoclonal bands are present on electrophoresis of concentrated CSF and also on concurrently tested serum of the same patient. The proper interpretation is...
cmpds based on molecular weight and size
nondiagnostic for MS
porphyrin and porphobilinogen screen
beta