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Test your basic knowledge |
Chemistry Certification
Start Test
Study First
Subject
:
certifications
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Fluctuation of the needle on a coulometric type titrator is most probably due to...
inhibitor binds to enzyme at same site as substrate
dirty electrodes
5
lead
2. The buffering capacity of blood is maintained by a reversible exchange process between bicarbonate and...
acute hepatitis
chloride
oxalacetate to malate
there is an absence of correlation
3. The unit of measure for a standard solution is...
run a new set of controls
CK-MB
beta
mg/ml
4. Alkaline phosphatase Slight increase - Aminotransferase Marked increase - Aspartate aminotransferase Marked increase - Alanine gamma-glutamyl transferase Slight increase
bicarbonate carbonic acid
acute hepatitis
hyperthyroidism
potassium dichromate in SA
5. Blood was collected in a serum separator tube from a patient who had been fasting since midnight. The time of collection was 7:00 AM. The laboratory test that should be re-collected is...
obstructive jaundice
transferrin
triglycerides
acid phosphatase
6. In competitive inhibition of an enzyme reaction the...
lipase
inhibitor binds to enzyme at same site as substrate
Wilson's disease
5
7. One means of checking a spectrophotometer wavelength calibration in the visible range is by using a...
SD over mean
high co2 and hco3
measures one ion more than others
didymium filter
8. A 45-year-old woman complains of fatigue - heat intolerance - and hair loss. Serum thyroxine and 125I-T3 resin uptake are abnormally low. What test would confirm that this is a pituitary deficiency?
cancel test
CML
TSH
band width
9. A 9-month-old boy from Israel has gradually lost the ability to sit up and develops seizures. He has an increased amount of a phospholipid called GM2-ganglioside in his neurons - and he lacks the enzyme hexosaminidase A in his leukocytes. These findi
0
aldolase
Tay-sachs
heparin
10. This condition does decrease activity of glucuronyl transferase result in increased unconjugated bilirubin and kernicterus in neonates
binding capacity of thyroxine-binding globulin
glass
crigler
ionic charge
11. In the atomic absorption method for calcium - lanthanum is used...
sodium
nephelometry
prevent phosphate interference
have a negative charge
12. Clinical assays for tumor markers are the most important for...
check serum for hemolysis
show a decrease in glycosylated hgb
monitoring the course of a known cancer
dirty electrodes
13. When taken by a euthyroid individual - oral contraceptives containing estrogens will have this effects on the thyroid function studies
breast cancer
GGT
D
increase in total circulating T4
14. The reason carbon monoxide is so toxic is because it...
200x affinity for oxygen
GLC
5
absorptivity x light path x concentration
15. The fast hemoglobin fraction is...
amylase
BUN 80
A1
there is an absence of correlation
16. In an internal standard flame photometer - the internal standard is used to...
correct for variations in flame and atomizer
bicarbonate buffer
low pH
conjugated hyperbilirubinemia - hepatocellular obstruction
17. This chemical determination may be of help in establishing the presence of seminal fluid
acid phosphatase
HDL
WITHOUT a disease with a negative test
boderline results test should be repeated
18. To ensure an accurate ammonia level result - the specimen should be...
5mg higher
urinary free cortisol
specimen exposure to light
spun separated iced and tested immediately
19. The methodology based on the amount of energy absorbed by a subtance as a function of its concentration and using a specific source of the same material as the substance analyzed is...
atomic absorption
porphobilinigen SCREEN
peptide bonds
conjugated hyperbilirubinemia - hepatocellular obstruction
20. A patient with glomerulonephritis would present the following serum results...
pituitary
high co2 and hco3
atomic absorption
BUN increased
21. Upon development of a thin layer chromatogram for the drug analysis - all drug spots (including the standards) had migrated with the solvent front. The most probable cause for this would be...
Tay-sachs
<1%
incorrect aqueous to nonaqueous mixture
Calcium - phosphorus
22. The osmolality of a urine or serum specimen is measured by a change in the...
cysteine
thyroxine binding globulin
freezing point
heparin
23. The osmolal gap is defined as measured Osm/kg minus the calculated Osm/kg. The average osmolal gap is near...
sodium potassium chloride CO2
viral hepatitis
maintain colloidal osmotic pressure
0
24. The most widely used support medium for electrophoretic separation of lipoproteins is...
peroxidase-like activity of hemoglobin
agarose
591
creatinine
25. At a pH of 8.6 the gamma globulins move toward the cathode - despite the fact that they are negatively charged. What is this phenomenon called?
endosmosis
prevent phosphate interference
hyperthyroidism
run a new set of controls
26. Oligoclonal bands are present on electrophoresis of concentrated CSF and also on concurrently tested serum of the same patient. The proper interpretation is...
acute intermittent porphyria
nondiagnostic for MS
D
GLC
27. In respiratory acidosis - a compensatory mechanism is the increase in...
nephelometry
binding capacity of thyroxine-binding globulin
sodium potassium chloride CO2
plasma bicarbonate
28. In electrophoretic analysis - buffers...
1 micromole per minute
act as carriers for ions
emphysema
fraction absorbed into systemic circulation
29. An HPLC operator notes that the column pressure is too high - is rising too rapidly - and the recorder output is not producing normal peaks. The most probable cause of the problem is...
freezing point
intestinal malabsorption
20:1
effluent line is obstructed
30. Given the following results: Alkaline phosphatase Marked increase Aminotransferase Slight increase Aspartate aminotransferase Slight increase Alanine gamma-glutamyl transferase Marked increase This is most consistent with...
1 mol/kg
LDH
Tay-sachs
obstructive jaundice
31. This would be an example of a glucose-specific colorimetric method
glucose oxidase
impaired response to ACTH stimulation
4.5
have a negative charge
32. This is a characteristic shared by lactate dehydrogenase - malate dehydrogenase - isocitrate dehydrogenase - and hydroxybutyrate dehydrogenase?
WITHOUT a disease with a negative test
show a decrease in glycosylated hgb
catalyze redox reactions
standard
33. A potentiometric electrode that measures an analyte that passes through a selectively premeable membrane and rapidly enters into an equilibrium with an electrolyte solution is...
2Na + glucose over 20 + BUN over 3
pCO2
measurement of absorbance at 450
Solute moves half the distance of the solvent front
34. A patient has the following results: Patient Values : Reference Values: Serum iron 250 ug/dL 60-150 ug/dL TIBC 350 ug/dL 300-35O ug/dL The best conclusion is that this patient has...
acute hepatitis
fraction absorbed into systemic circulation
biuret
iron hemochromatosis
35. The general types of interference in atomic absorption spectrophotometry...
200x affinity for oxygen
GFR
elevated lactic acid - elevated pyruvate
chemical ionization matrix
36. The preparation of a patient for standard tolerance testing should include...
high carbohydrate diet for 3 days
40-50
<45
glass
37. In amniotic fluid - the procedure used to detect Rh isosensitization is...
prisms and grating
5
T4 by RIA
measurement of absorbance at 450
38. Magnesium carbonate is added in an iron binding capacity determination in order to...
have a negative charge
tissue and serum levels need to reach equilibrium
remove excess unbound iron
<1%
39. Most drugs and intracellular metabolites measured by radioimmunoassay have molecular weights between 200 and 1000 and can be made immunogenic by...
peptide bonds
attaching them to protein molecules
chloride
faster than gamma
40. Amino acid associated with a sulfhydryl group
boderline results test should be repeated
cysteine
2-log(T)
40-50
41. The primary function of serum albumin in the peripheral blood is to...
maintain colloidal osmotic pressure
thyroxine binding globulin
plasma bicarbonate
primary hyperparathyroidism
42. The biuret reaction for the analysis of serum protein depends on the number...
without a disease with a negative test result
sharp fibrinogen peak
primidone
peptide bonds
43. This method offers the greatest sensitivity for HBsAg testing
thiamine
enzyme immunoassay
5
conjugated hyperbilirubinemia - hepatocellular obstruction
44. Technical problems encountered during the collection of an amniotic fluid specimen caused doubt as to whether the specimen was amniotic in origin. This procedure would establish that the fluid is amniotic in origin
creatinine
lead
increase in total circulating T4
whole blood can be used
45. Total iron-binding capacity measures the serum iron transporting capacity of...
run a new set of controls
transferrin
nephelometry
parathyroid
46. Diagnostic specificity is defined as the percentage of individuals...
specificity
WITHOUT a disease with a negative test
occult blood
purulent
47. A spectrophotometer is being considered for purchase by a small laboratory. This specification reflects the spectral purity of the instrument
ALP with fresh draw
band width
standard
fraction absorbed into systemic circulation
48. A patient has signs and symptoms suggestive of acromegaly. The diagnosis would be confirmed if the patient had...
be able to detect 9/10 simple instrument malfunctions
GGT
nondiagnostic for MS
no decrease in serum growth hormone after 90 minutes
49. An acid cleaning solution for glassware consists of...
potassium dichromate in SA
growth - third trimester of pregnancy
brain
5 tri 15 cholesterol 50 protein
50. Serum anion gap is increased in patients with...
lactic acidosis
iron hemochromatosis
amytriptyline 104
BUN 80