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Test your basic knowledge |
Chemistry Certification
Start Test
Study First
Subject
:
certifications
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Upon development of a thin layer chromatogram for the drug analysis - all drug spots (including the standards) had migrated with the solvent front. The most probable cause for this would be...
O2
fall in pH - rise in pCO2
lead
incorrect aqueous to nonaqueous mixture
2. Blood samples were collected at the beginning of an exercise class and after 30 minutes of aerobic activity. This would be most consistent with the postexercise sample
apoenzyme
g/MW
hepatobiliary (obstruction?)
elevated lactic acid - elevated pyruvate
3. The preparation of a patient for standard tolerance testing should include...
high carbohydrate diet for 3 days
Tay-sachs
lead
LDL
4. An acid cleaning solution for glassware consists of...
enzyme induction
ionization of carboxyl groups (yielding a net negative charge)
potassium dichromate in SA
be able to detect 9/10 simple instrument malfunctions
5. In familial hypercholesterolemia - the hallmark finding is an elevation of...
LDL
tissue and serum levels need to reach equilibrium
bone
<45
6. On immunoassays using enzyme-labeled antibodies or antigens: ___________ can be carried out with a spectrophotometer
quantitation of label
volumetric flask
draw blood for glucose and discontinue test
CO2 and pH elevated
7. In the immunoinhibition phase of the CK-MB procedure...
M subunit is inactivated
<45
D
prisms and grating
8. A 21-year-old man with nausea - vomiting - and jaundice has the following laboratory findings: Total serum bilirubin level: 8.5 mg/dL (normal - 0-1.0) Conjugated serum bilirubin level: 6.1 mg/dL (normal - 0-0.5) Urine urobilinogen: Increased Fecal u
LDH
conjugated hyperbilirubinemia - hepatocellular obstruction
120 minutes
specificity
9. Which blood gas electrode is composed of calomel and glass?
methyl alcohol
CO2
potassium dichromate in SA
lithium
10. In competitive inhibition of an enzyme reaction the...
inhibitor binds to enzyme at same site as substrate
placenta
bilirubindiglucuronide
ionic charge
11. The measurement of light scattered by particles in the sample is the principle of...
lithium
peptide bonds
nephelometry
100nmol
12. A reciprocal relationship exists between...
sharp fibrinogen peak
Calcium - phosphorus
changes in the fuel
591
13. A course of instruction is being planned to teach laboratory employees to correct simple malfunctions in selected laboratory instruments. In writing the objectives for this course - this would be most appropriate?
GGT
be able to detect 9/10 simple instrument malfunctions
MI
quantitation of label
14. Amniotic fluid submitted for a lecithin/sphingomyelin (US) ratio has been left in a brown container since the night before. You would expect...
electric current
decreased lecithin
thyroxine
21-hydroxylase deficiency
15. In monitoring glomerular function - this test has the highest sensitivity
atomic absorption
beta
creatinine clearance
respiratory acidosis
16. The hemoglobin that is resistant to alkali (KOH) denaturation is...
dirty electrodes
F
TSH
acute intermittent porphyria
17. The following blood gas results were obtained: pH : 7.18 PO2: 86 mm Hg PCO2: 60 mm Hg O2 saturation: 92% HCO3-: 21 mEq/L TCO2: 23 mEq/L Base excess: -8.0 mEq/L The patient's results are compatible with...
emphysema
atomic absorption
bone
sample exposed to light
18. In an internal standard flame photometer - the internal standard is used to...
respiratory ACIDOSIS
correct for variations in flame and atomizer
(testing of urine for) delta-am.. acid
band width
19. A blood gas sample was sent to the lab on ice - and a bubble was present in the syringe. The blood had been exposed to room air for at least 30 minutes. The following change in blood gases occurred...
glucose
32
increased O2 decreased HCO3
ionic charge
20. A serum sample was assayed for bilirubin at 10 AM and the result was 12 mg/dL. The same sample was retested at 3 PM. The result now is 8 mg/dL. The most likely explanation for this discrepancy is...
have a negative charge
sample exposed to light
diet
incorrect aqueous to nonaqueous mixture
21. An HPLC operator notes that the column pressure is too high - is rising too rapidly - and the recorder output is not producing normal peaks. The most probable cause of the problem is...
spun separated iced and tested immediately
effluent line is obstructed
increase in total circulating T4
MI
22. The enzyme present in almost all tissues that may be separated by electrophoresis into five components is...
LDH
pituitary
methadone
run a new set of controls
23. Scurvy is associated with deficiency of...
C
100 nmol
340
GFR
24. The protein portion of an enzyme complex is called the...
incorrect aqueous to nonaqueous mixture
prisms and grating
acute hepatitis
apoenzyme
25. The following results were obtained in a creatinine clearance evaluation: Urine concentration 84 mg/dL Urine volume 1440 mL/24 hr Serum concentration 1.4 mg/dL Body surface area 1.60 m2 (average = 1.73 m2) The creatinine cle~trance in mL/min is...
bicarbonate carbonic acid
1 micromole per minute
maintain colloidal osmotic pressure
65
26. Enzymes used in the diagnosis of acute pancreatitis?
monitoring the course of a known cancer
TSH
faster than gamma
amylase and lipase
27. Bromcresol purple at a pH of 5.2 is used in a colorimetric method to measure...
tissue and serum levels need to reach equilibrium
albumin
pO2 increased HCO3 decreased
normal - liver breakdown
28. A patient is admitted with biliary cirrhosis. If a serum protein electrophoresis is preformed - these globulin fractions will be most elevated?
beta
placenta
peptide bonds
parathyroid hormone
29. In a normal individual - injection of thyrotropin-releasing hormone (TRH) causes an increase in blood concentrations of this hormone
Prolactin
lower than in adults
9
GLC
30. Respiratory acidosis is described as a(n): ______ increase in CO2 decrease in pH
faster than gamma
adding an acid stabilizer
pH pCO2 pO2
glycerol
31. The function of the major lipid components of the very low density lipoproteins (VLDL) is to transport...
whole blood can be used
endogenous triglycerides
LDH
volumetric flask
32. The buffer pH most effective at allowing amphoteric proteins to migrate toward the cathode in an electrophoretic system would be...
4.5
oxalacetate to malate
HPLC analysis of porpobilinogen on 24hr urine
hyperthyroidism
33. The presence of this isoenzymes indicates acute myocardial damage
CK-MB
C
viral hepatitis
CO2 and pH elevated
34. This would be an example of a glucose-specific colorimetric method
parathyroid
attaching them to protein molecules
glucose oxidase
acute intermittent porphyria
35. Magnesium carbonate is added in an iron binding capacity determination in order to...
high co2 and hco3
remove excess unbound iron
fraction absorbed into systemic circulation
serum aliquots - one heated
36. In the liver - bilirubin is converted to...
F
fraction absorbed into systemic circulation
bilirubindiglucuronide
200
37. Aminotransferase enzymes catalyze the...
emphysema
pH pCO2 pO2
be able to detect 9/10 simple instrument malfunctions
exchange of amino and keto groups
38. The urea nitrogen concentration of a serum sample was measured as 15 mg/dL (atomic weights: carbon = 12 - oxygen = 16 - nitrogen = 14 - hydrogen = 1). The urea concentration of the same sample - in mg/dL - is...
primidone
can be separated into distinct phenotypes
32
catalyze redox reactions
39. A fresh urine sample is received for "porphyrins" or "porphyria" without further information or specifications. Initial analysis should include...
inclusion of smokers and nonsmokers in the study population
porphyrin and porphobilinogen screen
decreased lecithin
run a new set of controls
40. In electrophoresis of serum proteins - arifacts at the application point are most frequently caused by...
L/S ratio > 3.5
dirty applicators
cysteine
correct for variations in flame and atomizer
41. The TRH (thyrotropin-releasing hormone) stimulation test is useful in assessing...
0
valine leucine isoleucine
no decrease in serum growth hormone after 90 minutes
hyperthyroidism
42. An electrode has a silver/silver chloride anode and a platinum wire cathode. It is suspended in KCl solution and separated from the blood to be analyzed by a selectively permeable membrane. Such an electrode is used to measure...
O2
the fetus is at risk for respiratory distress
nephelometry
triglycerides
43. This wavelengths is within the ultraviolet rang.
measures one ion more than others
manic-depression
340
didymium filter
44. The method of choice for diagnosis of a protracted attack of porphyria is...
Tay-sachs
hepatobiliary (obstruction?)
the same as plasma glucose
HPLC analysis of porpobilinogen on 24hr urine
45. The nanometer is a measurement of...
beta
wavelength
triglycerides
5mg higher
46. The ability of a procedure to measure only the component(s) it claims to measure is called...
albumin
decreased lecithin
specificity
Tay-sachs
47. This chemical determination may be of help in establishing the presence of seminal fluid
acid phosphatase
5
C
lipase
48. A common cause of respiratory alkalosis is...
hyperventilation
inclusion of smokers and nonsmokers in the study population
TSH
Temperature is a function of the number of particles in solution
49. The unit of measure for a standard solution is...
CML
SD over mean
mg/ml
5 tri 15 cholesterol 50 protein
50. Ion selective electrodes are called selective rather than specific because they actually measure the...
TSH
measures one ion more than others
thyroxine
C3 complement