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Test your basic knowledge |
Chemistry Certification
Start Test
Study First
Subject
:
certifications
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. A patient had the following serum results: Na+ 140 mEq/L K+ 4.0 mEq/L Glucose 95 mg/dL BUN 10 mg/dL Which osmolality is consistent with these results?
acid phosphatase
270
creatinine
cyclic antidepressants
2. Which two conditions can "physiologically" elevate serum alkaline phosphatase?
viral hepatitis
4.5
porphobilinigen SCREEN
growth - third trimester of pregnancy
3. Serum haptoglobin...
remove excess unbound iron
can be separated into distinct phenotypes
lead
Hb S
4. Certain enzymes are activated to metabolize drugs as a result of another drug action. This is referred to as...
enzyme induction
acute intermittent porphyria
can be separated into distinct phenotypes
normal - liver breakdown
5. This serum constituent is unstable if a blood specimen is left standing at room temperature for 8 hours before processing
acute hepatitis
glucose
pH = pKa + log (salt/acid)
65
6. Sixty to seventy-five percent of the plasma cholesterol is transported by...
changes in the fuel
alkaline picrate
atomic absorption
LDL
7. Amniotic fluid submitted for a lecithin/sphingomyelin (US) ratio has been left in a brown container since the night before. You would expect...
conjugated hyperbilirubinemia - hepatocellular obstruction
decreased lecithin
sodium
corticosterone
8. In the liver - bilirubin is converted to...
specimen exposure to light
bilirubindiglucuronide
diet
iron hemochromatosis
9. The main reason for suboptimal drug levels in therapeutic drug monitoring is...
sharp cutoff filter
patient noncompliance
immunofixation
TLC
10. Alkaline phosphatase Slight increase - Aminotransferase Marked increase - Aspartate aminotransferase Marked increase - Alanine gamma-glutamyl transferase Slight increase
pH = pKa + log (salt/acid)
lactic acidosis
acute hepatitis
exposure to CO
11. In an internal standard flame photometer - the internal standard is used to...
correct for variations in flame and atomizer
TSH
TSH
electric current
12. Scurvy is associated with deficiency of...
C
5 tri 15 cholesterol 50 protein
incorrect aqueous to nonaqueous mixture
glucose
13. This hemoglobin has glucose-6-phosphate on the amino-terminal valine of the beta chain?
is quantitated by the amount of light produced
diet
A1c
effluent line is obstructed
14. Serum and urine copper levels are assayed on a hospital patient with the following results: Patient Serum Cu: 58 ug/dL; Reference Value:70-140 ug/dL Patient Urine Cu: 83 ug/dL ; Reference Value: < 40 ug/dL This is most consistent with...
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15. Measurement of total T4 by competitive protein binding or displacement is based on the specific binding properties of...
increase in total circulating T4
fresh morning urine for delta-aminolevulinic acid
creatine kinase
thyroxine binding globulin
16. The osmolality of a urine or serum specimen is measured by a change in the...
freezing point
can be used for absorbtion - partition - ion exchange - and gel permeation chromatography
Temperature is a function of the number of particles in solution
B12 deficiency
17. A blood sample was received from the emergency room with a request for narcotic analysis. The request slip indicated that the patient (a known heroin addict) responded to naloxone administration. The serum was negative for morphine by EIA. What other
methadone
F
acid phosphatase
exchange of amino and keto groups
18. The following five sodium control values (mEq/L) were obtained:140 - 135 - 138 - 140 - 142Calculate the coefficient of variation.
no decrease in serum growth hormone after 90 minutes
Temperature is a function of the number of particles in solution
amylase
1.9
19. Estrogen and progesterone receptor assays are useful in assessing prognosis in...?
breast cancer
creatine kinase
obstructive jaundice
thyroxine binding globulin
20. The TRH (thyrotropin-releasing hormone) stimulation test is useful in assessing...
glass
hyperthyroidism
occult blood
chloride
21. Major actions of angiotensin II include...
bicarbonate buffer
CK
biuret
increased vasoconstriction
22. A true statement about high performance liquid chromatography (HPLC) is that it...
CO2 and pH elevated
BUN 80
can be used for absorbtion - partition - ion exchange - and gel permeation chromatography
20:1
23. This would be an example of a glucose-specific colorimetric method
NADH
chylomicrons VLDL
glucose oxidase
digoxin
24. The principle of the occult blood test depends on the...
multiplied by 4
biuret
peroxidase-like activity of hemoglobin
(testing of urine for) delta-am.. acid
25. The presence of this isoenzymes indicates acute myocardial damage
parathyroid
CK-MB
para-hydroxylphenyl...
iron deficiency anemia
26. The enzyme that exists chiefly in skeletal muscle - heart - and brain; is grossly elevated in active muscular dystrophy; and rises early in myocardial infarction is...
low pH
mg/ml
porphobilinogen screen
creatine kinase
27. Creatinine clearance is used to estimate the...
TLC
without a disease with a negative test result
cmpds based on molecular weight and size
GFR
28. If the correlation coefficient (r) of two variables is zero...
there is an absence of correlation
GFR
manic-depression
1:5
29. The following results were obtained in a creatinine clearance evaluation: Urine concentration 84 mg/dL Urine volume 1440 mL/24 hr Serum concentration 1.4 mg/dL Body surface area 1.60 m2 (average = 1.73 m2) The creatinine cle~trance in mL/min is...
apoenzyme
lead
65
emphysema
30. In performing a spinal fluid protein determination - the specimen is diluted 1 part spinal fluid to 3 parts saline to obtain a result low enough to measure. To calculate the protein concentration the result must be...
lipase
glucose
multiplied by 4
TSH
31. The osmolal gap is defined as measured Osm/kg minus the calculated Osm/kg. The average osmolal gap is near...
0
no ice clots bubbles
sodium
Mg
32. In competitive inhibition of an enzyme reaction the...
crigler
inhibitor binds to enzyme at same site as substrate
270
minimize the effects of interference
33. Calcium concentration in the serum is regulated by...
glucose
properties of the membrane
parathyroid hormone
chloride
34. This diseases results from a familial absence of high-density lioprotein
exposure to CO
Tangier
peptide bonds
dirty electrodes
35. A 21-year-old man with nausea - vomiting - and jaundice has the following laboratory findings: Total serum bilirubin level: 8.5 mg/dL (normal - 0-1.0) Conjugated serum bilirubin level: 6.1 mg/dL (normal - 0-0.5) Urine urobilinogen: Increased Fecal u
HPLC analysis of porpobilinogen on 24hr urine
porphobilinogen synthetase
standard
conjugated hyperbilirubinemia - hepatocellular obstruction
36. Most chemical methods for determining total protein utilize this reaction?
dirty electrodes
biuret
creatine kinase
bilirubin
37. A low concentrarion of serum phosphorus is commonly found in...
sample exposed to light
carbohydrate hyperalimentation
serum cortisol > 15
bicarbonate buffer
38. One means of checking a spectrophotometer wavelength calibration in the visible range is by using a...
show a decrease in glycosylated hgb
analyzed immediately
carbs
didymium filter
39. Phenobarbital is a metabolite of...
primidone
2Na + glucose over 20 + BUN over 3
elevated lactic acid - elevated pyruvate
parathyroid hormone
40. A 9-month-old boy from Israel has gradually lost the ability to sit up and develops seizures. He has an increased amount of a phospholipid called GM2-ganglioside in his neurons - and he lacks the enzyme hexosaminidase A in his leukocytes. These findi
200x affinity for oxygen
sharp fibrinogen peak
multiplied by 4
Tay-sachs
41. The following data were obtained from a cellulose acetate protein electrophoresis scan: Albumin area 75 units Gamma globulin area 30 units Total area 180 units Total protein 6.5 g/dL The gamma globulin content in g/dL is...
lead
1.1
cancel test
ceruplasmin
42. In familial hypercholesterolemia - the hallmark finding is an elevation of...
can be used for absorbtion - partition - ion exchange - and gel permeation chromatography
100 nmol
LDL
valine leucine isoleucine
43. The unit of measure for a standard solution is...
lithium
Hb S
mg/ml
remove excess unbound iron
44. The most important buffer pair in plasma is the...
bicarbonate carbonic acid
crigler
enzyme induction
inhibitor binds to enzyme at same site as substrate
45. Characteristic of the Bence Jones protein that is used to distinguish it from other urinary proteins is its solubility...
<1%
@ 100
freezing point
urinary free cortisol
46. A potassium level of 6.8 mEq/L is obtained. Before reporting the results - the first step the technologist should take is to...
respiratory ACIDOSIS
check serum for hemolysis
elevated lactic acid - elevated pyruvate
is quantitated by the amount of light produced
47. Clinical assays for tumor markers are the most important for...
draw blood for glucose and discontinue test
monitoring the course of a known cancer
cyclic antidepressants
sodium potassium chloride CO2
48. A psychiatric patient was experiencing sever depression - but responded to treatment with amitriptyline with no apparent side effects. A blood sample was sent to the laboratory for therapeutic monitoring. Which drug level would be MOST reflective of
run a new set of controls
lithium
amytriptyline 104
cholesterol normal triglycerides elevated
49. In amniotic fluid - the procedure used to detect Rh isosensitization is...
LDL
0
measurement of absorbance at 450
C
50. Patients with Cushing's syndrome exhibit...
benzoylecogine
inclusion of smokers and nonsmokers in the study population
GGT
serum cortisol > 15