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Test your basic knowledge |
Chemistry Certification
Start Test
Study First
Subject
:
certifications
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. A serum sample was assayed for bilirubin at 10 AM and the result was 12 mg/dL. The same sample was retested at 3 PM. The result now is 8 mg/dL. The most likely explanation for this discrepancy is...
methadone
chylomicrons VLDL
cholesterol normal triglycerides elevated
sample exposed to light
2. The definitive diagnosis of primary adrenal insufficiency requires demonstration of...
adding an acid stabilizer
chloride
obstructive jaundice
impaired response to ACTH stimulation
3. Most chemical methods for determining total protein utilize this reaction?
O2
changes in the fuel
run a new set of controls
biuret
4. This electrolyte is the chief plasma cation whose main function is maintaining osmotic pressure
correct for variations in light intensity
benzoylecogine
glycerol
sodium
5. The most heat labile fraction of alkaline phosphatase is obtained from...
bone
scattered at a right angle
2Na + glucose over 20 + BUN over 3
3500
6. In monitoring glomerular function - this test has the highest sensitivity
(testing of urine for) delta-am.. acid
sodium potassium chloride CO2
minimize the effects of interference
creatinine clearance
7. Upon development of a thin layer chromatogram for the drug analysis - all drug spots (including the standards) had migrated with the solvent front. The most probable cause for this would be...
attaching them to protein molecules
HPLC analysis of porpobilinogen on 24hr urine
act as carriers for ions
incorrect aqueous to nonaqueous mixture
8. Total iron-binding capacity measures the serum iron transporting capacity of...
cancel test
scattered at a right angle
draw blood for glucose and discontinue test
transferrin
9. Phenobarbital is a metabolite of...
have a negative charge
digoxin
enzyme induction
primidone
10. In automated methods utilizing a bichromatic analyzer - dual wavelengths are employed to...
T4 by RIA
pituitary
occult blood
minimize the effects of interference
11. Before unconjugated bilirubin can react with Ehrlich's diazo reagent - this must be added
methyl alcohol
no decrease in serum growth hormone after 90 minutes
ALP with fresh draw
tissue and serum levels need to reach equilibrium
12. The following data were obtained from a cellulose acetate protein electrophoresis scan: Albumin area 75 units Gamma globulin area 30 units Total area 180 units Total protein 6.5 g/dL The gamma globulin content in g/dL is...
90%
1.1
urinary free cortisol
21-hydroxylase deficiency
13. The most sensitive enzymatic indicator for liver damage from ethanol intake is...
3500
thiamine
emphysema
GGT
14. Coulometry is used to measure...
100 nmol
Solute moves half the distance of the solvent front
chloride
HCT
15. This chemical determination may be of help in establishing the presence of seminal fluid
patient noncompliance
acid phosphatase
placenta
metabolic acidosis
16. Gel filtration chromatography is used to separate...
cmpds based on molecular weight and size
benzoylecogine
lead
1.9
17. While performing a serum lithium determination on a flame photometer with cesium as the internal standard - the technologist noticed that there was a flickering flame. The most probable cause of this problem is...
hyperthyroidism
changes in the fuel
one micromole/minute
Wilson's disease
18. When separating serum proteins by cellulose acetate electrophoresis using veronal buffer at pH 8.6 - beta globulin migrates...
porphyrin and porphobilinogen screen
Wilson's disease
9
faster than gamma
19. The formula for calculating the amount of moles of a chemical?
porphobilinogen synthetase
g/MW
CK
591
20. High levels of which lipoprotein class are associated with decreased risk of accelerated atherosclerosis?
HDL
peptide bonds
have a negative charge
TSH
21. A patient is admitted to the emergency room in a state of metabolic alkalosis.This would be consistent with this diagnosis?
lithium
specificity
high co2 and hco3
iron hemochromatosis
22. A blood gas sample was sent to the lab on ice - and a bubble was present in the syringe. The blood had been exposed to room air for at least 30 minutes. The following change in blood gases occurred...
minimize the effects of interference
increased O2 decreased HCO3
bilirubin
pituitary
23. An acid cleaning solution for glassware consists of...
potassium dichromate in SA
growth - third trimester of pregnancy
Tangier
act as carriers for ions
24. In the Jaffe reaction - creatine reacts with...
improving state of metabolic control (as indicated by fructosamine)
methyl alcohol
alkaline picrate
A1c
25. A person suspected of having metabolic alkalosis would have these laboratory findings
CO2 and pH elevated
obstructive jaundice
impaired response to ACTH stimulation
trig
26. Four children are admitted with malaise - anorexia - and abdominal pain. Further evaluations reveal mild anemia - erythrocyte basophilic stippling - and profound pica habits. Poisoning by which heavy metal is most likely responsible?
exposure to CO
lead
Temperature is a function of the number of particles in solution
peroxidase-like activity of hemoglobin
27. The normal concentration of proteins in cerebrospinal fluid - relative to serum protein - is...
creatinine
specificity
<1%
lithium
28. Unless blood gas measurements are made immediately after sampling - in vitro glycolysis of the blood causes a...
fall in pH - rise in pCO2
WITHOUT a disease with a negative test
occult blood
40-50
29. In developing the reference for a new EIA for CEA - the range for the normal population was broader than that published by the vendor. Controls are acceptable with a narrow coefficient of variation. This may be explained by...
D
TLC
inclusion of smokers and nonsmokers in the study population
draw blood for glucose and discontinue test
30. This wavelengths is within the ultraviolet rang.
glucose tolerance test
40-50
340
1:5
31. A psychiatric patient was experiencing sever depression - but responded to treatment with amitriptyline with no apparent side effects. A blood sample was sent to the laboratory for therapeutic monitoring. Which drug level would be MOST reflective of
TSH
amytriptyline 104
carbs
check serum for hemolysis
32. The identification of Bence Jones protein is best accomplished by...
TSH
immunofixation
5
quantitation of label
33. At blood pH 7.40 what is the ratio between bicarbonate and carbonic acid?
prevent phosphate interference
20:1
respiratory acidosis
triglycerides
34. The biologically most active - naturally occuring androgen is...
viral hepatitis
testosterone
F
electric current
35. Blood samples were collected at the beginning of an exercise class and after 30 minutes of aerobic activity. This would be most consistent with the postexercise sample
elevated lactic acid - elevated pyruvate
urinary free cortisol
metabolic acidosis
enzyme induction
36. Zinc protoporphyrin or free erythrocyte protoporphyrin measurements are useful to assess blood concentrations of...
lead
run a new set of controls
mg/ml
acute hepatitis
37. This lipid results would be expected to be falsely elevated on a serum specimen from a nonfasting patient
1.1
trig
g/MW
bone
38. The concentration of serum carotene is affected MOST by...
enzyme immunoassay
L/S ratio > 3.5
90%
diet
39. A blood sample was received from the emergency room with a request for narcotic analysis. The request slip indicated that the patient (a known heroin addict) responded to naloxone administration. The serum was negative for morphine by EIA. What other
methadone
ratio of distance moved by solvent to distance moved by compound
atomic absorption
growth - third trimester of pregnancy
40. When taken by a euthyroid individual - oral contraceptives containing estrogens will have this effects on the thyroid function studies
pilocarpine
increase in total circulating T4
90%
acute hepatitis
41. A cardiac glycoside that is used in the treatment of congenital heart failure and arrhythmias by increasing the force and velocity of myocardial contraction is...
agarose
specimen exposure to light
200x affinity for oxygen
digoxin
42. The direction in which albumin migrates (ie - toward anode or cathode) during electrophoretic separation of serum proteins - at pH 8.6 - is determined by...
ionization of carboxyl groups (yielding a net negative charge)
TSH
freezing point
serum cortisol > 15
43. The buffering capacity of blood is maintained by a reversible exchange process between bicarbonate and...
chloride
pilocarpine
potassium dichromate in SA
nephelometry
44. The ability of a procedure to measure only the component(s) it claims to measure is called...
5 tri 15 cholesterol 50 protein
100nmol
specificity
exchange of amino and keto groups
45. An increase in serum acetone is indicative of a defect in the metabolism of...
carbs
agarose
check serum for hemolysis
GLC
46. An electrode has a silver/silver chloride anode and a platinum wire cathode. It is suspended in KCl solution and separated from the blood to be analyzed by a selectively permeable membrane. Such an electrode is used to measure...
hyperthyroidism
absorptivity x light path x concentration
creatinine clearance
O2
47. A patient with type I insulin-dependent diabetes mellitus has the following results: Fasting blood glucose: 150 mg/dL (70-110 rng/dL) Hemoglobin A1c: 25% (6.0%-19.5%) Fructosamine: 3.0 mmol/L ( 2.0-5.3 mmol/L)
exchange of amino and keto groups
increase in total circulating T4
improving state of metabolic control (as indicated by fructosamine)
sodium
48. This disease is associated with the greatest elevation of lactate dehydrogenase isoenzyme 1?
fetal and placenta function
B12 deficiency
iron hemochromatosis
5 tri 15 cholesterol 50 protein
49. One international unit of enzyme activity is the amount of enzyme that - under specified reaction conditions of substrate concentration - pH - and temperature - causes utilization of substrate at the rate of...
4.5
LDL
pO2 increased HCO3 decreased
one micromole/minute
50. A patient with hemolytic anemia will...
high carbohydrate diet for 3 days
obstructive jaundice
show a decrease in glycosylated hgb
electric current