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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Made from orogate precuror with PRPP added later
pyrimadines
Double Strand DNA repair
Collagen
Digoxin (cardiac glycosides)
2. Inhibits bacterials dihydrofolate reducatese down thymine
In eukaryotes the starting amino acid is...
Molecular motor protiesn
Aminoacylt - tRNA synthetase
trimethoprim
3. Seals
Cholchicine
Chloramphenicol
DNA ligase
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
4. Prokaryotic only. Degrades RNA primer and fills in the gap with DNA (5 prime to 3 prime exonuclease)
DNA pol I
Double Strand DNA repair
Chediak Higashi syndrome
Fluoroquinolones
5. Bind 50S blocking translocation
Where do introns and exons stay
Macrolides
methionine is only encoded by
The only histone not on the core
6. Never go to Go divide rapidly with short G1 bone marrow - gut epithelium - skin - hair follicles
Covalent alterations
Labile
Thymine has a
tRNA aminoacylation
7. The 3 prime hydroxyl of the nascent chain is the target
Which end of a growing DNA strand is the target
Clindamycin
Tumor Suppressors
Cilia structure
8. 1P blocked by chloramphenicaol and macrolide
Prokaryote RNA pol
Example of permanent cells
Translocation
DNA topoisomerases
9. Condensed - transciptionally inactive HC- Highly condensed
Heterochromatin
Cilia structure
Eukaroytes
nucleosid
10. Site where RNA polymerase and multiple other transciption factors bind to DNA upstream from gene locus (AT rich upstream sequence with TATA and CAAT boxes)
Termination
promoter
What ties teh nucleosome together
Cyclins
11. Cleave terminal regions of procollagen to transform into insoluable tropocolagen
unambiguous
Outside the cell what processing must be done in procolalgen
Going APE
transition
12. CCA AT 3 PRIME END
White codon is at the 3 prime end of a tRNA
DNA topoisomerases
histone octamer names
Elastase is inhibited by
13. Splicing out of introns
Order of mitosis
Excocytosis of collagen
Step Three of RNA processing
intermediate filaments
14. Microvilli - muscle contraction - cytokinesis - adhering juntions
nonsense
Enhancers and silencer may be located_____
Paclitaxil
actin and myosin
15. 1) primary transcript combines with snRNPs and other proteins to form spliceosome 2) lariat shaped intermediate is generated 3) Lariat is removed and released to precisely join 2 exons
Steps in splicing
DNA/RNA/Protein syntesis direction
Paclitaxil
transition
16. Odd 30S plus 50 S=70S
silent mutation
Prokaryotes
Cyclins
Initial transcript without processing is known as
17. Substituting a pyramidine for a pyrimadine
tRNA aminoacylation
transition
AUG codes For what in prokaryotes
transversion
18. Hydroxy proline and hydroxylysine
Eukaroytes
Xeroderma pigmentosum
A- T
Hydroxylation of which amino acids are attached to Glycine to form collagen
19. Y shaped region along DNA template where leading and lagging strands are syntehsized
degenerate or redundant
C- G bond
Replication fork
DNA pol I
20. Promoter - enhancer - promoter - TATA- transcription initiation site - coding region (including exons and introns) and then the AATAAA
polyadenylation does/does not require a template
Functional organization of the gene
Which end of the nucleotide has the triphosphate
Translocation
21. Bind 30S subunit preventing attachment of aminoacyl - tRNA
Proteosomal degradation
Higher the cholesterol or long saturated fatty acid content
Tetracyclines
mRNA start codons
22. 3 H bonds
Prokaryote RNA pol
tRNA
C- G bond
the tRNA- amino acid bond
23. Antifungal - act on microtubules
polyadenylation does/does not require a template
Kartageners syndrome
Mebendazole/thiabendazole
Griseofulvin
24. Base + ribose
Deamination of cytosine makes
nucleosid
helicase
RNA polymerases in eukaryotes
25. The 5prime end (energy for the bond)
polyadenylation does/does not require a template
Neurofilaments
mRNA stop codons
Which end of the nucleotide has the triphosphate
26. Anit helminth - act on microtubules
Outside the cell what processing must be done in procolalgen
single stranded binding proteinds
Mebendazole/thiabendazole
step two of RNA processing
27. Less condensed - transciptionally active=eu truly transcobed
Euchromatin
RNA polymerases in eukaryotes
Molecular motor protiesn
kinesin
28. Even 40S 60S =80S
Cholchicine
Free ribosomes
capped and tail transcript is called
Eukaroytes
29. Inhibits the atpase which increases intracellular sodium which increases intracellular calcium increases cardiaccontractility
Axonemal dyenin
Digoxin (cardiac glycosides)
tRNA activation
Total energy expenditure requirement for translocation
30. Create a nick in the helix to relieve supercoils created during replication
Excocytosis of collagen
cytokeratin
DNA topoisomerases
What does the hydroxylation of proline and lysine require
31. Greater melting temperature lower fluidity
Higher the cholesterol or long saturated fatty acid content
White codon is at the 3 prime end of a tRNA
Immunohistochemical stains vimentin
mRNA stop codons
32. UGA - UAG - UAA
Ehlers Danlos
Promoter mutation
5FU
mRNA stop codons
33. Exocytose procollagen into extracellylar sace
DNA pol III
Mismatch repair
tRNA activation
Excocytosis of collagen
34. Blocks denovo purine synthesis
Purines
Order of mitosis
6MP
Axonemal dyenin
35. Negatively charged DNA loops twice around histone octamers create a nucloesome bead.
mRNA stop codons
chromatin structure
CDKs
silent mutation
36. Inhibits by binding to the potassium side
Deamination of cytosine makes
tRNA activation
Chediak Higashi syndrome
Oubain
37. 1P (blocked by tetracycline)
Type IV collagen is an important structural component of...
Griseofulvin
Loading tRNA on to ribosome energy requirement
RNA polymerases in eukaryotes
38. 1 RNA polymerase (multisubunite complex) makes all 3 kinds of RNA
Double Strand DNA repair
Outside the cell what processing must be done in procolalgen
Tumor Suppressors
Prokaryote RNA pol
39. Be So Totatally Cool Read Books (bOne - CarTWOlage - Threeticular - Type IV under the floor)
capped and tail transcript is called
Collagen
5FU
cytokeratin
40. Aminoacyl - tRNA binds to A site 2) peptidyltransferase catalyzes peptide bond formation transfers growing polypeptie to amino acid in A site 3) ribosome advances 3 nucleotides toward the 3 prime end of RNA moving peptiydyl RNA to P site
Guanine has a
Elongation
unambiguous
Which end of a growing DNA strand is the target
41. Anti cancer - act on microtubules
Elastin
Kartageners syndrome
Mebendazole/thiabendazole
Vincristine/Vinblastine
42. Regulatory proteins that control cell cycle events; phase specific; activated CDKs
RNA polymerases in eukaryotes
What type of collagen is most affected in Ehlers Danlos
unambiguous
Cyclins
43. Binds 50S blocking translocation
Clindamycin
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
Neurofilaments
Going APE
44. Must be both activated and inactivated for cell cycle to progress
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
Cell cycle
Cyclin - CDK
Promoter mutation
45. Unattached to any membrane; site of cytosolic and organeller prtoeins
Free ribosomes
Order of mitosis
DNA pol III
Purines
46. Inhbits RNA pol II (found in death cap mushrooms)
tRNA Structure
DNA pol I
Eukaroytes
alpha amintin
47. Elastase
microtubule
Griseofulvin
tRNA Structure
Elastin is broken down by
48. HS1 - HSB - H2 - H4
histone octamer names
AUG codes For what in prokaryotes
Tetracyclines
desmin
49. Codes for formyl methionine (f - Met)
AUG codes For what in prokaryotes
methionine is only encoded by
Primase
Higher the cholesterol or long saturated fatty acid content
50. Read froma fixed starting point as a continous sequenecs of bases
commaless - non - overlapping
AUG codes For what in prokaryotes
missense mutation
alpha amintin