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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Anit helminth - act on microtubules
Mebendazole/thiabendazole
Higher the cholesterol or long saturated fatty acid content
hydroxyurea
Free ribosomes
2. Mutation in nucleotide excision repair Dry skin with melanoma and other cancers
Xeroderma pigmentosum
The only histone not on the core
Higher the cholesterol or long saturated fatty acid content
Type IV collagen is an important structural component of...
3. Elastase
Proofreading function in eukaryotic RNA
Steps in splicing
Elastin is broken down by
methionine is only encoded by
4. Cilia - glagella - mitotic spindle - neurons - centrioles
Mismatch repair
microtubule
Protein synthesis initiation
tRNA Structure
5. Immotile cilia due to a dyenin arm defect. Results in male nad female inferticility (sperm immotile) - bronchiectasis - and recurrent sinusisits - associated with situs inversus
nucleosid
microtubule
Where do introns and exons stay
Kartageners syndrome
6. Proline - glycine
step two of RNA processing
Where do introns and exons stay
Free ribosomes
Common amino acids in elastin
7. Change resulting in misreading of all nucleotides downstream - usually resulting in a truncated non functional protien
Mebendazole/thiabendazole
frame shift
Chediak Higashi syndrome
Step one of RNA processing
8. Inhibits bacterials dihydrofolate reducatese down thymine
origin of replication
Tetracyclines
Total energy expenditure requirement for translocation
trimethoprim
9. Non homologous end joining
Double Strand DNA repair
Common amino acids in elastin
tRNA aminoacylation
Loading tRNA on to ribosome energy requirement
10. Genetic code is conserved throughout evolution
universal
Replication fork
Plasma membrane composition
Post - translational modifications
11. Alpha 1 antitrypisn
Single Strand DNA Repair types
Elastase is inhibited by
Replication fork
Total energy expenditure requirement for translocation
12. Unattached to any membrane; site of cytosolic and organeller prtoeins
DNA topoisomerases
silent mutation
histone octamer names
Free ribosomes
13. Seals
mRNA start codons
Methotrexate
the tRNA- amino acid bond
DNA ligase
14. Inhibits ribonucleotide reductase
hydroxyurea
Axonemal dyenin
origin of replication
nucleotide
15. Inhibits dihydrofolate reductase down thymine
Associations of Ehlers Danlos
Tetracyclines
Digoxin (cardiac glycosides)
Methotrexate
16. In the nucleus after transcitpion and only processed RNA is transporte out of the nucleus
Common amino acids in elastin
Elastin is broken down by
Elastase is inhibited by
RNA processing in eukaryotes occurs
17. Commonly results in dramatic decrease in amount of gene transcribed
Methotrexate
Elongation
Which is the most and least abundant type of RNA
Promoter mutation
18. Inhibits thymidylate synthase down thymine
Which end of the tRNA is the amino acid bound to?
Glycosolation
5FU
Free ribosomes
19. Type III
Euchromatin
What type of collagen is most affected in Ehlers Danlos
Free ribosomes
Paclitaxil
20. The 3 prime hydroxyl of the nascent chain is the target
Which end of a growing DNA strand is the target
Chloramphenicol
the tRNA- amino acid bond
promoter
21. Antifungal - act on microtubules
Collagedn synthesis where?
Griseofulvin
Prokaryotes
Thymine has a
22. Three amino acids necessary for purine synthesis= glutamine - aspartate and glycine
Kartageners syndrome
Nucleotide excision repair
Aminoglycosides
Gag on pure gold
23. Same aa often base change in 3rd position of codon
Step Three of RNA processing
silent mutation
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
DNA ligase
24. Nucleotide excision repair - Base Excision repair - Mismath repair
DNA/RNA/Protein syntesis direction
polyadenylation does/does not require a template
Single Strand DNA Repair types
Plasma membrane composition
25. Genetic bone disorder (brittle bone disease) type 1 colalgen - fractures (during birth) 2) Blue sclerae 3) hearing loss 4) dental imperfections 1:10000 may be confused with child abuse
Which end of the nucleotide has the triphosphate
Covalent alterations
Osteogenesis Imperfecta
kinesin
26. Each codon specifies only 1 amino acid
unambiguous
Introns
Labile
tRNA activation
27. 1P blocked by chloramphenicaol and macrolide
methionine is only encoded by
5FU
Step one of RNA processing
Translocation
28. Contain the actual genetic information coding for protein
Exons
Associations of Ehlers Danlos
Labile
What does the hydroxylation of proline and lysine require
29. Be So Totatally Cool Read Books (bOne - CarTWOlage - Threeticular - Type IV under the floor)
Step Three of RNA processing
Collagen
nucleotide
DNA pol I
30. A site - incoming aminoacyl tRNA - Psite accomodates growing Peptide - E site holds EmplytRNA as it exits
histone octamer names
Going APE
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
DNA/RNA/Protein syntesis direction
31. 3 H bonds
Replication fork
Collagedn synthesis where?
C- G bond
Ehlers Danlos
32. Muscle
transition
Which end of the tRNA is the amino acid bound to?
desmin
Base excision repair
33. Introns stay In the nucleus whereas EXons EXit and are EXpressed
Collagedn synthesis where?
Where do introns and exons stay
Heterochromatin
Total energy expenditure requirement for translocation
34. Unmethylated - newly synthesized string is recognized - mismatched nucleotides are removed and the gap is filled and resealed
Mismatch repair
What ties teh nucleosome together
Thymine has a
Gag on pure gold
35. Odd 30S plus 50 S=70S
Prokaryotes
tRNA
Going APE
RNA polymerases in eukaryotes
36. 4 high enrgy bonds
Total energy expenditure requirement for translocation
Oubain
The only histone not on the core
Enhancers and silencer may be located_____
37. Intervening noncoding segments of DNA
Axonemal dyenin
mRNA start codons
Introns
AUG codes For what in prokaryotes
38. Inhibit formation of the initation complex and cause misreading of mRNA
Aminoglycosides
Associations of Ehlers Danlos
missense mutation
Plasma membrane composition
39. Prevents stranges from reannealing
Oubain
Primase
Which end of a growing DNA strand is the target
single stranded binding proteinds
40. More than 1 codon may code for the same amino acid
degenerate or redundant
origin of replication
White codon is at the 3 prime end of a tRNA
Methotrexate
41. Unwinds DNA template at replication fork
pyrimadines
Collagedn synthesis where?
Rough ER
helicase
42. Anti breast cancer - acts on mts
RNA polymerases in eukaryotes
the tRNA- amino acid bond
Elastin
Paclitaxil
43. CCA AT 3 PRIME END
White codon is at the 3 prime end of a tRNA
universal
Paclitaxil
intermediate filaments
44. The N to C
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
Rough ER
tRNA aminoacylation
Protein synthesis is in which direction
45. Microvilli - muscle contraction - cytokinesis - adhering juntions
actin and myosin
Cilia structure
nucleosid
trimethoprim
46. Made from IMP precursor
Tropocollagen cross links between_____ to form____
purines
Aminoglycosides
The only histone not on the core
47. UGA - UAG - UAA
Step Three of RNA processing
mRNA stop codons
GFAP
nucleotide
48. Asymmetric fluid bilayer - contains - cholesterol - phospholipids - sphingoplipids - glycolipids - and protiends
Euchromatin
Mebendazole/thiabendazole
AUG codes For what in prokaryotes
Plasma membrane composition
49. 75-90 nucleotides - 2ary structure cloverleaf form anticodon end is opposite 3 prime aminoacyl end
tRNA Structure
DNA topoisomerases
Chloramphenicol
mRNA stop codons
50. CUT 1 ring Cut the Py
Proteosomal degradation
Pyrimidines
tRNA aminoacylation
Double Strand DNA repair