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First Aid: Biochemistry Molecular

Instructions:
  • Answer 50 questions in 15 minutes.
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  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Checkpoints control transition between phases of cell cycle. regulated by cyclins - CDKs and tumor suppressors. Mitosis (shortest phse)






2. Regulatory proteins that control cell cycle events; phase specific; activated CDKs






3. Prevents stranges from reannealing






4. Uracil






5. H1






6. Poly adenylation






7. Inhibits dihydrofolate reductase down thymine






8. HS1 - HSB - H2 - H4






9. Elastase






10. Connective tissue






11. Change resulting in misreading of all nucleotides downstream - usually resulting in a truncated non functional protien






12. GTP






13. Accurate base pairing is required only in the first 2 nucleotide positions of an mRNA so codons differing ht e3rd wobble psoition may code for the same tRNA/amino acid code






14. Must be both activated and inactivated for cell cycle to progress






15. Odd 30S plus 50 S=70S






16. Three amino acids necessary for purine synthesis= glutamine - aspartate and glycine






17. More than 1 codon may code for the same amino acid






18. RNA polymerase I makes rRNA - RNA pol II makes mRNA - RNA pol III makes tRNA






19. Specific endonucleases release the oligonucleotide containing damaged bases. DNA polymerase and logase fill and resealt eh gap






20. Unwinds DNA template at replication fork






21. Introns stay In the nucleus whereas EXons EXit and are EXpressed






22. Bind 50S blocking translocation






23. You glyucosolate hte pro - alpha chain lysine resudens and form procollagen (triple helix of alpha chains)






24. Inhibit DNA gyrase (specific prokaryotic topoisomerase)






25. Specific glycosylases recognize and remove damaged bases - AP endonuclease cuts DNA at pyrimidne site - empty sugar is removed and the gap is filled and resealed






26. Cleave terminal regions of procollagen to transform into insoluable tropocolagen






27. Responsible for the accuracy of amino acid selection






28. Less condensed - transciptionally active=eu truly transcobed






29. Intervening noncoding segments of DNA






30. 9+2 arrangement of microtubules -






31. Ketone






32. Microtubule polymerization defect resulting in lowered phagocytosis. results in recurrent pyogenic infections - partial albinism and peripheral neuropathy






33. 3 sodium out for 2 potassium in (nout - kin)takes 1 atp and the machine is phosphorylated during the machine cycle






34. Site of secretory protiens (mucus secreting goblet cells and antibody secreting cells)






35. Greater melting temperature lower fluidity






36. Blocks denovo purine synthesis






37. Cylindrical structure composed of helical array of plymerized dimers of alpha and beta tubulin - flagella - cilia - mitotic spindle - grows slowly collapses quickly






38. Made from IMP precursor






39. Lysine/hydroxylysine and combines to form collagen






40. Base+ribose+phosphate linked by a phosphodiester bond






41. Prokaryotic only. Elongates leading strand by adding deoxynucleotides to the 3prime end. Elongates laggin strand. 3 prime to 5 prime exonuclease activity






42. Retrograde to microtubules






43. Inhibits bacterials dihydrofolate reducatese down thymine






44. Activated by GTP hydrolosis initiation factors help assembel the 40 S ribosomal subunites with the initiatior tRNA and are released whent he mRNA and the ribosomal subunit assemple with the complex






45. Antigout - acts on mts






46. 3 H bonds






47. Anti cancer - act on microtubules






48. MRNA






49. Aminoacyl - tRNA binds to A site 2) peptidyltransferase catalyzes peptide bond formation transfers growing polypeptie to amino acid in A site 3) ribosome advances 3 nucleotides toward the 3 prime end of RNA moving peptiydyl RNA to P site






50. Seals