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First Aid: Biochemistry Molecular

Instructions:
  • Answer 50 questions in 15 minutes.
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  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Substituting a pyramidine for a pyrimadine






2. Hn RNA






3. H1 string






4. 4 high enrgy bonds






5. Scrutinizes aa before and after it binds to tRNA. If incorrect bond is hydrolyzed.






6. AD and AR- associated iwth joint dislocation - berry aneurysms - organ rupture






7. Epithelial cells






8. AUG inAUGurates protein synthesis






9. Changed aaconservative - new aa is similar in chemical structure






10. Unattached to any membrane; site of cytosolic and organeller prtoeins






11. Elastase






12. Odd 30S plus 50 S=70S






13. Commonly results in dramatic decrease in amount of gene transcribed






14. Antigout - acts on mts






15. Tansport cellular cargo toward opposite ends of microtubule tracks






16. More than 1 codon may code for the same amino acid






17. A malfunction of mismatch repair (MUt L etc..)






18. Uracil






19. Inhibit formation of the initation complex and cause misreading of mRNA






20. Anti breast cancer - acts on mts






21. Accurate base pairing is required only in the first 2 nucleotide positions of an mRNA so codons differing ht e3rd wobble psoition may code for the same tRNA/amino acid code






22. Antifungal - act on microtubules






23. Negatively charged DNA loops twice around histone octamers create a nucloesome bead.






24. Splicing out of introns






25. Close to - far from or even within (in an intron) the gene whose expression it regulates






26. Contain the actual genetic information coding for protein






27. Immotile cilia due to a dyenin arm defect. Results in male nad female inferticility (sperm immotile) - bronchiectasis - and recurrent sinusisits - associated with situs inversus






28. Bind 50S blocking translocation






29. Lysine/hydroxylysine and combines to form collagen






30. Specific endonucleases release the oligonucleotide containing damaged bases. DNA polymerase and logase fill and resealt eh gap






31. Retrograde to microtubules






32. Bm - kidney - ears and eyes






33. Blocks denovo purine synthesis






34. Made from IMP precursor






35. RNA polymerase I makes rRNA - RNA pol II makes mRNA - RNA pol III makes tRNA






36. Genetic code is conserved throughout evolution






37. GTP






38. 1P blocked by chloramphenicaol and macrolide






39. Specific glycosylases recognize and remove damaged bases - AP endonuclease cuts DNA at pyrimidne site - empty sugar is removed and the gap is filled and resealed






40. Methyl THYmine has a meTHYl






41. Greater melting temperature lower fluidity






42. Poly adenylation






43. Particular sequnece in genomre where DNA replication begins. May be single (prokaryotes) or multiple (eukaryotes)






44. ATP






45. 1) primary transcript combines with snRNPs and other proteins to form spliceosome 2) lariat shaped intermediate is generated 3) Lariat is removed and released to precisely join 2 exons






46. Prokaryotic only. Elongates leading strand by adding deoxynucleotides to the 3prime end. Elongates laggin strand. 3 prime to 5 prime exonuclease activity






47. Trimming removal of n or c terminal propeptides from zymogens to generate mature proteinds






48. CUT 1 ring Cut the Py






49. Y shaped region along DNA template where leading and lagging strands are syntehsized






50. Bind 30S subunit preventing attachment of aminoacyl - tRNA