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First Aid: Biochemistry Molecular

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Create a nick in the helix to relieve supercoils created during replication






2. Site where negative regulators bind






3. Base + ribose






4. A site - incoming aminoacyl tRNA - Psite accomodates growing Peptide - E site holds EmplytRNA as it exits






5. RNA polymerase I makes rRNA - RNA pol II makes mRNA - RNA pol III makes tRNA






6. Regulatory proteins that control cell cycle events; phase specific; activated CDKs






7. Never go to Go divide rapidly with short G1 bone marrow - gut epithelium - skin - hair follicles






8. Introns stay In the nucleus whereas EXons EXit and are EXpressed






9. Antigout - acts on mts






10. Substituting a pyramidine for a pyrimadine






11. Change resulting in early stop codon






12. Methyl THYmine has a meTHYl






13. Each codon specifies only 1 amino acid






14. Genetic bone disorder (brittle bone disease) type 1 colalgen - fractures (during birth) 2) Blue sclerae 3) hearing loss 4) dental imperfections 1:10000 may be confused with child abuse






15. Brings together 2 ends of DNA fragments no requirement for homology






16. Capping on 5 prime end (7 methylguanosine) -






17. Lysine/hydroxylysine and combines to form collagen






18. Blocks denovo purine synthesis






19. Mutation in nucleotide excision repair Dry skin with melanoma and other cancers






20. Unattached to any membrane; site of cytosolic and organeller prtoeins






21. Attachment of ubiquitin to defective proteinds to tag them for breakdown






22. Binds 50S blocking translocation






23. RER translation of collagen alpha chains (preprocollagen) usually Gly-X-Y






24. Cyclin depndent kinases; consituative and inactive






25. Three amino acids necessary for purine synthesis= glutamine - aspartate and glycine






26. ATP






27. Muscle






28. Prokaryotic only. Elongates leading strand by adding deoxynucleotides to the 3prime end. Elongates laggin strand. 3 prime to 5 prime exonuclease activity






29. (A - G) 2 rings Pure As Gold






30. A malfunction of mismatch repair (MUt L etc..)






31. Ribonucleotide reductase






32. Epithelial cells






33. Made from orogate precuror with PRPP added later






34. Inhbits RNA pol II (found in death cap mushrooms)






35. Nucleotide excision repair - Base Excision repair - Mismath repair






36. In the nucleus after transcitpion and only processed RNA is transporte out of the nucleus






37. VItamin C






38. Connective tissue






39. Inhibit DNA gyrase (specific prokaryotic topoisomerase)






40. HS1 - HSB - H2 - H4






41. Seals






42. Trimming removal of n or c terminal propeptides from zymogens to generate mature proteinds






43. 75-90 nucleotides - 2ary structure cloverleaf form anticodon end is opposite 3 prime aminoacyl end






44. Prophas - metaphase - anaphase telophase






45. 2 H bonds greater GC content greater melting point






46. Made from IMP precursor






47. Vimentin - desmin - cytockeratin - glial fibrillary acid proteins - neurofilaments






48. Uracil






49. Inhibits the atpase which increases intracellular sodium which increases intracellular calcium increases cardiaccontractility






50. Site of dteroid synthesis and detoxification of druigs and poisons (liver hepatocytes and steroid horomore adrenal cortex)