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First Aid: Biochemistry Molecular

Subjects : health-sciences, first-aid

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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1. Nucleotide excision repair - Base Excision repair - Mismath repair
single stranded binding proteinds
Replication fork
Single Strand DNA Repair types
frame shift

2. A site - incoming aminoacyl tRNA - Psite accomodates growing Peptide - E site holds EmplytRNA as it exits
Introns
Going APE
helicase
Alternate splicing

3. Particular sequnece in genomre where DNA replication begins. May be single (prokaryotes) or multiple (eukaryotes)
DNA pol III
transition
Prokaryote RNA pol
origin of replication

4. Seals
Post - translational modifications
DNA ligase
polyadenylation does/does not require a template
silent mutation

5. Prokaryotic only. Degrades RNA primer and fills in the gap with DNA (5 prime to 3 prime exonuclease)
Eukaroytes
Cyclins
Axonemal dyenin
DNA pol I

6. Less condensed - transciptionally active=eu truly transcobed
Euchromatin
tRNA Structure
microtubule
Purines

7. Prokaryotic only. Elongates leading strand by adding deoxynucleotides to the 3prime end. Elongates laggin strand. 3 prime to 5 prime exonuclease activity
The only histone not on the core
Mebendazole/thiabendazole
Going APE
DNA pol III

8. Attachment of ubiquitin to defective proteinds to tag them for breakdown
Which end of the tRNA is the amino acid bound to?
Proteosomal degradation
Griseofulvin
RNA processing in eukaryotes occurs

9. 9+2 arrangement of microtubules -
Covalent alterations
Which is the most and least abundant type of RNA
Cilia structure
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon

10. Has enough energy to created the peptide bond
Which end of the tRNA is the amino acid bound to?
the tRNA- amino acid bond
Elastin is broken down by
desmin

11. Scrutinizes aa before and after it binds to tRNA. If incorrect bond is hydrolyzed.
Termination
Chloramphenicol
Xeroderma pigmentosum
Aminoacylt - tRNA synthetase

12. Ketone
Guanine has a
Chediak Higashi syndrome
DNA ligase
Higher the cholesterol or long saturated fatty acid content

13. Retrograde to microtubules
dyenin
What ties teh nucleosome together
White codon is at the 3 prime end of a tRNA
Immunohistochemical stains vimentin

14. Makes an RNA primer on which DNA polymerase II can initiate replication
Chediak Higashi syndrome
alpha amintin
Primase
Going APE

15. The 3 prime end
promoter
Oubain
Permanent cells
Which end of the tRNA is the amino acid bound to?

16. Anti breast cancer - acts on mts
Promoter mutation
Cholchicine
Paclitaxil
tRNA activation

17. 5 prime to 3 prime
Translocation
What type of collagen is most affected in Ehlers Danlos
Griseofulvin
mRNA is syntehsized in which direction?

18. Bind 50S blocking translocation
Macrolides
desmin
Which end of a growing DNA strand is the target
Cholchicine

19. Responsible for the accuracy of amino acid selection
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
Excocytosis of collagen
Order of mitosis
Cholchicine

20. HS1 - HSB - H2 - H4
origin of replication
6MP
microtubule
histone octamer names

21. Non homologous end joining
Which end of a growing DNA strand is the target
Double Strand DNA repair
frame shift
Clindamycin

22. CCA AT 3 PRIME END
Protein synthesis initiation
White codon is at the 3 prime end of a tRNA
Cilia structure
Promoter mutation

23. Proline - glycine
Osteogenesis Imperfecta
Common amino acids in elastin
intermediate filaments
hydroxyurea

24. A malfunction of mismatch repair (MUt L etc..)
Eukaroytes
Elongation
Hereditary non polyposis colorectal cancer
Smooth ER

25. Aminoacyl - tRNA binds to A site 2) peptidyltransferase catalyzes peptide bond formation transfers growing polypeptie to amino acid in A site 3) ribosome advances 3 nucleotides toward the 3 prime end of RNA moving peptiydyl RNA to P site
DNA topoisomerases
Exons
Elongation
Digoxin (cardiac glycosides)

26. P53 and RB normally inhibit g1 to S progression
desmin
Tumor Suppressors
Base excision repair
Immunohistochemical stains vimentin

27. RER translation of collagen alpha chains (preprocollagen) usually Gly-X-Y
Collagedn synthesis where?
Elastase is inhibited by
origin of replication
transversion

28. Exocytose procollagen into extracellylar sace
alpha amintin
tRNA Structure
Excocytosis of collagen
Paclitaxil

29. Even 40S 60S =80S
Eukaroytes
transversion
nucleosid
mRNA stop codons

30. You glyucosolate hte pro - alpha chain lysine resudens and form procollagen (triple helix of alpha chains)
Digoxin (cardiac glycosides)
Gag on pure gold
Glycosolation
actin and myosin

31. Vimentin - desmin - cytockeratin - glial fibrillary acid proteins - neurofilaments
intermediate filaments
Tumor Suppressors
Common amino acids in elastin
Outside the cell what processing must be done in procolalgen

32. Faulty collagen synthesis causing 1) hyperextensible skin 2) tendency to bleed 3) hypermobile joints
Loading tRNA on to ribosome energy requirement
unambiguous
alpha amintin
Ehlers Danlos

33. Binds 50S blocking translocation
Clindamycin
Euchromatin
Ehlers Danlos
dyenin

34. 75-90 nucleotides - 2ary structure cloverleaf form anticodon end is opposite 3 prime aminoacyl end
C- G bond
Chediak Higashi syndrome
Elongation
tRNA Structure

35. G1 - S - G2 - Mitosis
hydroxyurea
tRNA Structure
Labile
Cell cycle order

36. Prevents stranges from reannealing
DNA topoisomerases
single stranded binding proteinds
Outside the cell what processing must be done in procolalgen
silent mutation

37. Neurons
Neurofilaments
DNA topoisomerases
alpha amintin
Chloramphenicol

38. 1P blocked by chloramphenicaol and macrolide
transition
Where do introns and exons stay
6MP
Translocation

39. VItamin C
C- G bond
What does the hydroxylation of proline and lysine require
transition
Deamination of cytosine makes

40. Brings together 2 ends of DNA fragments no requirement for homology
Excocytosis of collagen
Non homologous end joining
Axonemal dyenin
Gag on pure gold

41. Unwinds DNA template at replication fork
Silencer
helicase
commaless - non - overlapping
Xeroderma pigmentosum

42. Substituting a pyramidine for a pyrimadine
Total energy expenditure requirement for translocation
Alternate splicing
Step one of RNA processing
transition

43. Different exons can be combined to make nique protiens in different times
C- G bond
Step one of RNA processing
Alternate splicing
actin and myosin

44. Microtubule polymerization defect resulting in lowered phagocytosis. results in recurrent pyogenic infections - partial albinism and peripheral neuropathy
Chediak Higashi syndrome
silent mutation
Tumor Suppressors
promoter

45. Cleave terminal regions of procollagen to transform into insoluable tropocolagen
Outside the cell what processing must be done in procolalgen
Glycosolation
Functional organization of the gene
Translocation

46. Be So Totatally Cool Read Books (bOne - CarTWOlage - Threeticular - Type IV under the floor)
mRNA stop codons
Cell cycle
Collagen
Cell cycle order

47. Cylindrical structure composed of helical array of plymerized dimers of alpha and beta tubulin - flagella - cilia - mitotic spindle - grows slowly collapses quickly
microtubule
transition
The only histone not on the core
pyrimadines

48. Microvilli - muscle contraction - cytokinesis - adhering juntions
actin and myosin
Order of mitosis
What ties teh nucleosome together
desmin

49. Y shaped region along DNA template where leading and lagging strands are syntehsized
Replication fork
Prokaryotes
histone octamer names
Total energy expenditure requirement for translocation

50. Create a nick in the helix to relieve supercoils created during replication
DNA topoisomerases
Digoxin (cardiac glycosides)
A- T
Termination

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First Aid: Biochemistry Molecular

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