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First Aid: Biochemistry Molecular

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. 1P blocked by chloramphenicaol and macrolide






2. Promoter - enhancer - promoter - TATA- transcription initiation site - coding region (including exons and introns) and then the AATAAA






3. Strethchy protein within lungs - large artiers - elastic liaments - vocal cords - ligamenta flava)






4. Alpha 1 antitrypisn






5. No proofreading function but can initiate chains. RNA poymerase II opens DNA at promoter site






6. Cyclin depndent kinases; consituative and inactive






7. Bind 30S subunit preventing attachment of aminoacyl - tRNA






8. Genetic code is conserved throughout evolution






9. Read froma fixed starting point as a continous sequenecs of bases






10. Aminoacyl - tRNA binds to A site 2) peptidyltransferase catalyzes peptide bond formation transfers growing polypeptie to amino acid in A site 3) ribosome advances 3 nucleotides toward the 3 prime end of RNA moving peptiydyl RNA to P site






11. H1






12. Epithelial cells






13. Rampant - Massive - TIny rRNA is most common - then mRNA and then tRNA






14. 4 high enrgy bonds






15. One codon AUG






16. Scrutinizes aa before and after it binds to tRNA. If incorrect bond is hydrolyzed.






17. Xlinked recessive IV collagen bm - kidney - ear and eye -- nephritis and defness ocular disturbances






18. Antifungal - act on microtubules






19. Binds 50S blocking translocation






20. Inhibit formation of the initation complex and cause misreading of mRNA






21. Elastase






22. Microvilli - muscle contraction - cytokinesis - adhering juntions






23. Cilia - glagella - mitotic spindle - neurons - centrioles






24. RER translation of collagen alpha chains (preprocollagen) usually Gly-X-Y






25. Activated by GTP hydrolosis initiation factors help assembel the 40 S ribosomal subunites with the initiatior tRNA and are released whent he mRNA and the ribosomal subunit assemple with the complex






26. Changed aaconservative - new aa is similar in chemical structure






27. GTP






28. 3 H bonds






29. Create a nick in the helix to relieve supercoils created during replication






30. UGA - UAG - UAA






31. Methyl THYmine has a meTHYl






32. Ketone






33. Muscle






34. Inhbits RNA pol II (found in death cap mushrooms)






35. Inhibit DNA gyrase (specific prokaryotic topoisomerase)






36. Made from IMP precursor






37. Prokaryotic only. Degrades RNA primer and fills in the gap with DNA (5 prime to 3 prime exonuclease)






38. Must be both activated and inactivated for cell cycle to progress






39. CUT 1 ring Cut the Py






40. Anterograde to microtubule






41. Specific glycosylases recognize and remove damaged bases - AP endonuclease cuts DNA at pyrimidne site - empty sugar is removed and the gap is filled and resealed






42. Inhibits thymidylate synthase down thymine






43. Vimentin - desmin - cytockeratin - glial fibrillary acid proteins - neurofilaments






44. Substituting a pyramidine for a pyrimadine






45. H1 string






46. A malfunction of mismatch repair (MUt L etc..)






47. Unmethylated - newly synthesized string is recognized - mismatched nucleotides are removed and the gap is filled and resealed






48. Attachment of ubiquitin to defective proteinds to tag them for breakdown






49. Inhibits the atpase which increases intracellular sodium which increases intracellular calcium increases cardiaccontractility






50. Checkpoints control transition between phases of cell cycle. regulated by cyclins - CDKs and tumor suppressors. Mitosis (shortest phse)