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First Aid: Biochemistry Molecular

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Negatively charged DNA loops twice around histone octamers create a nucloesome bead.






2. 3 H bonds






3. Intervening noncoding segments of DNA






4. Inhibits the atpase which increases intracellular sodium which increases intracellular calcium increases cardiaccontractility






5. The 5prime end (energy for the bond)






6. No proofreading function but can initiate chains. RNA poymerase II opens DNA at promoter site






7. A site - incoming aminoacyl tRNA - Psite accomodates growing Peptide - E site holds EmplytRNA as it exits






8. Cyclin depndent kinases; consituative and inactive






9. Condensed - transciptionally inactive HC- Highly condensed






10. The N to C






11. Site where RNA polymerase and multiple other transciption factors bind to DNA upstream from gene locus (AT rich upstream sequence with TATA and CAAT boxes)






12. Specific endonucleases release the oligonucleotide containing damaged bases. DNA polymerase and logase fill and resealt eh gap






13. Close to - far from or even within (in an intron) the gene whose expression it regulates






14. The 3 prime end






15. Particular sequnece in genomre where DNA replication begins. May be single (prokaryotes) or multiple (eukaryotes)






16. Microtubule polymerization defect resulting in lowered phagocytosis. results in recurrent pyogenic infections - partial albinism and peripheral neuropathy






17. Same aa often base change in 3rd position of codon






18. Be So Totatally Cool Read Books (bOne - CarTWOlage - Threeticular - Type IV under the floor)






19. Base + ribose






20. Hn RNA






21. Scrutinizes aa before and after it binds to tRNA. If incorrect bond is hydrolyzed.






22. More than 1 codon may code for the same amino acid






23. Immotile cilia due to a dyenin arm defect. Results in male nad female inferticility (sperm immotile) - bronchiectasis - and recurrent sinusisits - associated with situs inversus






24. Splicing out of introns






25. 1) primary transcript combines with snRNPs and other proteins to form spliceosome 2) lariat shaped intermediate is generated 3) Lariat is removed and released to precisely join 2 exons






26. Odd 30S plus 50 S=70S






27. Even 40S 60S =80S






28. Checkpoints control transition between phases of cell cycle. regulated by cyclins - CDKs and tumor suppressors. Mitosis (shortest phse)






29. 1 RNA polymerase (multisubunite complex) makes all 3 kinds of RNA






30. Stretch of DNA that alters gene expression by binding transcription factors






31. Phosphorylation - glycosloation - hyderoxylation






32. Poly adenylation






33. H1 string






34. Three amino acids necessary for purine synthesis= glutamine - aspartate and glycine






35. MRNA






36. Inhibit DNA gyrase (specific prokaryotic topoisomerase)






37. P53 and RB normally inhibit g1 to S progression






38. Nucleotide excision repair - Base Excision repair - Mismath repair






39. Makes an RNA primer on which DNA polymerase II can initiate replication






40. Antifungal - act on microtubules






41. Never go to Go divide rapidly with short G1 bone marrow - gut epithelium - skin - hair follicles






42. Strethchy protein within lungs - large artiers - elastic liaments - vocal cords - ligamenta flava)






43. Promoter - enhancer - promoter - TATA- transcription initiation site - coding region (including exons and introns) and then the AATAAA






44. CUT 1 ring Cut the Py






45. ATP






46. Create a nick in the helix to relieve supercoils created during replication






47. Capping on 5 prime end (7 methylguanosine) -






48. 3 sodium out for 2 potassium in (nout - kin)takes 1 atp and the machine is phosphorylated during the machine cycle






49. Xlinked recessive IV collagen bm - kidney - ear and eye -- nephritis and defness ocular disturbances






50. 2 H bonds greater GC content greater melting point