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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Inhibit formation of the initation complex and cause misreading of mRNA
5FU
RNA polymerases in eukaryotes
Neurofilaments
Aminoglycosides
2. RER translation of collagen alpha chains (preprocollagen) usually Gly-X-Y
Oubain
Functional organization of the gene
Deamination of cytosine makes
Collagedn synthesis where?
3. Base + ribose
nucleosid
methionine is only encoded by
tRNA Structure
Euchromatin
4. Y shaped region along DNA template where leading and lagging strands are syntehsized
Euchromatin
Eukaroytes
Replication fork
Which end of the tRNA is the amino acid bound to?
5. 2 H bonds greater GC content greater melting point
In eukaryotes the starting amino acid is...
A- T
frame shift
Purines
6. Alpha 1 antitrypisn
The only histone not on the core
Sodium K ATPase
Cholchicine
Elastase is inhibited by
7. Prokaryotic only. Elongates leading strand by adding deoxynucleotides to the 3prime end. Elongates laggin strand. 3 prime to 5 prime exonuclease activity
Excocytosis of collagen
Digoxin (cardiac glycosides)
DNA pol III
unambiguous
8. Genetic code is conserved throughout evolution
Molecular motor protiesn
Which is the most and least abundant type of RNA
tRNA activation
universal
9. Prokaryotic only. Degrades RNA primer and fills in the gap with DNA (5 prime to 3 prime exonuclease)
DNA pol I
kinesin
What does the hydroxylation of proline and lysine require
Cholchicine
10. Change resulting in early stop codon
transition
nonsense
Guanine has a
dyenin
11. Never go to Go divide rapidly with short G1 bone marrow - gut epithelium - skin - hair follicles
Labile
Promoter mutation
Clindamycin
frame shift
12. Capping on 5 prime end (7 methylguanosine) -
RNA polymerases in eukaryotes
Tumor Suppressors
Step one of RNA processing
Xeroderma pigmentosum
13. ATP
Oubain
Example of permanent cells
cytokeratin
tRNA activation
14. Inhibits ribonucleotide reductase
hydroxyurea
universal
Cyclin - CDK
Chloramphenicol
15. (A - G) 2 rings Pure As Gold
Alternate splicing
Introns
Purines
Collagen
16. Remain in G0 regenerate from stem cells
Mebendazole/thiabendazole
Permanent cells
Purines
Which end of a growing DNA strand is the target
17. GTP
Euchromatin
actin and myosin
tRNA gripping and going places
Pyrimidines
18. Checkpoints control transition between phases of cell cycle. regulated by cyclins - CDKs and tumor suppressors. Mitosis (shortest phse)
mRNA stop codons
Cell cycle
White codon is at the 3 prime end of a tRNA
Example of permanent cells
19. Cylindrical structure composed of helical array of plymerized dimers of alpha and beta tubulin - flagella - cilia - mitotic spindle - grows slowly collapses quickly
Primase
Prokaryote RNA pol
microtubule
frame shift
20. H1 string
Exons
What ties teh nucleosome together
Common amino acids in elastin
DNA pol I
21. Unwinds DNA template at replication fork
helicase
Protein synthesis is in which direction
Mebendazole/thiabendazole
Neurofilaments
22. Seals
Total energy expenditure requirement for translocation
Enhancers and silencer may be located_____
Tropocollagen cross links between_____ to form____
DNA ligase
23. MRNA
Outside the cell what processing must be done in procolalgen
C- G bond
Alports syndrome
capped and tail transcript is called
24. Uracil
Deamination of cytosine makes
capped and tail transcript is called
tRNA aminoacylation
transversion
25. Be So Totatally Cool Read Books (bOne - CarTWOlage - Threeticular - Type IV under the floor)
Translocation
Smooth ER
Elongation
Collagen
26. Inhibits dihydrofolate reductase down thymine
Glycosolation
What ties teh nucleosome together
Methotrexate
DNA pol III
27. Type III
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
Alports syndrome
What type of collagen is most affected in Ehlers Danlos
step two of RNA processing
28. Asymmetric fluid bilayer - contains - cholesterol - phospholipids - sphingoplipids - glycolipids - and protiends
Protein synthesis is in which direction
Plasma membrane composition
nucleosid
Proteosomal degradation
29. A malfunction of mismatch repair (MUt L etc..)
DNA/RNA/Protein syntesis direction
Hereditary non polyposis colorectal cancer
C- G bond
Thymine has a
30. Has enough energy to created the peptide bond
origin of replication
Total energy expenditure requirement for translocation
the tRNA- amino acid bond
Fluoroquinolones
31. Enter G1 from G0 when stimulated Hepatocytes/lymphocytes
Stable (quiescent)
White codon is at the 3 prime end of a tRNA
6MP
Excocytosis of collagen
32. The 5prime end (energy for the bond)
Which end of the nucleotide has the triphosphate
microtubule
Cilia structure
Euchromatin
33. Specific endonucleases release the oligonucleotide containing damaged bases. DNA polymerase and logase fill and resealt eh gap
Collagen
Thymine has a
Nucleotide excision repair
helicase
34. Inhibits thymidylate synthase down thymine
5FU
Protein synthesis initiation
Fluoroquinolones
Exons
35. Contain the actual genetic information coding for protein
5FU
desmin
Exons
Methotrexate
36. 75-90 nucleotides - 2ary structure cloverleaf form anticodon end is opposite 3 prime aminoacyl end
tRNA Structure
Alports syndrome
Loading tRNA on to ribosome energy requirement
degenerate or redundant
37. AD and AR- associated iwth joint dislocation - berry aneurysms - organ rupture
Chediak Higashi syndrome
Associations of Ehlers Danlos
hydroxyurea
5FU
38. Made from IMP precursor
purines
A- T
Heterochromatin
desmin
39. Inhibits bacterials dihydrofolate reducatese down thymine
Covalent alterations
trimethoprim
Mismatch repair
Functional organization of the gene
40. Bm - kidney - ears and eyes
Steps in splicing
Type IV collagen is an important structural component of...
Post - translational modifications
Replication fork
41. 1P blocked by chloramphenicaol and macrolide
Translocation
The only histone not on the core
mRNA is syntehsized in which direction?
pyrimadines
42. No proofreading function but can initiate chains. RNA poymerase II opens DNA at promoter site
Silencer
single stranded binding proteinds
Proofreading function in eukaryotic RNA
Clindamycin
43. Trimming removal of n or c terminal propeptides from zymogens to generate mature proteinds
Aminoglycosides
Outside the cell what processing must be done in procolalgen
Enhancer
Post - translational modifications
44. A site - incoming aminoacyl tRNA - Psite accomodates growing Peptide - E site holds EmplytRNA as it exits
C- G bond
purines
Going APE
Introns
45. Inhibits 50S peptidyl transferase
Chloramphenicol
silent mutation
nonsense
Digoxin (cardiac glycosides)
46. Does not
Cell cycle order
polyadenylation does/does not require a template
Initial transcript without processing is known as
Prokaryotes
47. Greater melting temperature lower fluidity
pyrimadines
Higher the cholesterol or long saturated fatty acid content
Griseofulvin
mRNA start codons
48. Different exons can be combined to make nique protiens in different times
Alternate splicing
Clindamycin
Cyclins
DNA pol III
49. RNA polymerase I makes rRNA - RNA pol II makes mRNA - RNA pol III makes tRNA
Elastin is broken down by
Higher the cholesterol or long saturated fatty acid content
Loading tRNA on to ribosome energy requirement
RNA polymerases in eukaryotes
50. Muscle
helicase
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
desmin
Heterochromatin