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Test your basic knowledge |
First Aid: Biochemistry Molecular
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Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
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study here
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Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Inhibits 50S peptidyl transferase
Protein synthesis initiation
tRNA
Replication fork
Chloramphenicol
2. Base + ribose
Cholchicine
purines
Vincristine/Vinblastine
nucleosid
3. AUG inAUGurates protein synthesis
Alternate splicing
mRNA start codons
alpha amintin
Proofreading function in eukaryotic RNA
4. HS1 - HSB - H2 - H4
Non homologous end joining
histone octamer names
What does the hydroxylation of proline and lysine require
Rough ER
5. Xlinked recessive IV collagen bm - kidney - ear and eye -- nephritis and defness ocular disturbances
tRNA gripping and going places
nonsense
Non homologous end joining
Alports syndrome
6. Stretch of DNA that alters gene expression by binding transcription factors
tRNA activation
Translocation
CDKs
Enhancer
7. Substituting a purine for a pyrimdine or vice versa
GFAP
DNA/RNA/Protein syntesis direction
transversion
DNA ligase
8. Faulty collagen synthesis causing 1) hyperextensible skin 2) tendency to bleed 3) hypermobile joints
Ehlers Danlos
RNA polymerases in eukaryotes
6MP
cytokeratin
9. GTP
hydroxyurea
Cilia structure
Step one of RNA processing
tRNA gripping and going places
10. Tansport cellular cargo toward opposite ends of microtubule tracks
Covalent alterations
Molecular motor protiesn
commaless - non - overlapping
Functional organization of the gene
11. RNA polymerase I makes rRNA - RNA pol II makes mRNA - RNA pol III makes tRNA
missense mutation
Prokaryote RNA pol
RNA polymerases in eukaryotes
Total energy expenditure requirement for translocation
12. Even 40S 60S =80S
Eukaroytes
Elastase is inhibited by
Silencer
Which end of a growing DNA strand is the target
13. G1 - S - G2 - Mitosis
Functional organization of the gene
Cell cycle order
Termination
Guanine has a
14. The N to C
Protein synthesis is in which direction
polyadenylation does/does not require a template
transition
GFAP
15. Hydroxy proline and hydroxylysine
Hydroxylation of which amino acids are attached to Glycine to form collagen
Exons
kinesin
Total energy expenditure requirement for translocation
16. Anterograde to microtubule
kinesin
Aminoglycosides
Protein synthesis is in which direction
Non homologous end joining
17. In the nucleus after transcitpion and only processed RNA is transporte out of the nucleus
Prokaryote RNA pol
Double Strand DNA repair
RNA processing in eukaryotes occurs
Permanent cells
18. Does not
6MP
Vincristine/Vinblastine
polyadenylation does/does not require a template
DNA ligase
19. AD and AR- associated iwth joint dislocation - berry aneurysms - organ rupture
Associations of Ehlers Danlos
nucleotide
microtubule
Macrolides
20. Base+ribose+phosphate linked by a phosphodiester bond
Digoxin (cardiac glycosides)
Heterochromatin
nucleotide
Double Strand DNA repair
21. Must be both activated and inactivated for cell cycle to progress
Euchromatin
Cyclin - CDK
Functional organization of the gene
Step Three of RNA processing
22. Lysine/hydroxylysine and combines to form collagen
Heterochromatin
Cilia structure
Tropocollagen cross links between_____ to form____
DNA/RNA/Protein syntesis direction
23. Ribonucleotide reductase
Chloramphenicol
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
Nucleotide excision repair
Proteosomal degradation
24. Cyclin depndent kinases; consituative and inactive
Thymine has a
CDKs
Which end of the tRNA is the amino acid bound to?
tRNA aminoacylation
25. H1
Hydroxylation of which amino acids are attached to Glycine to form collagen
Axonemal dyenin
desmin
The only histone not on the core
26. Promoter - enhancer - promoter - TATA- transcription initiation site - coding region (including exons and introns) and then the AATAAA
Covalent alterations
Which end of a growing DNA strand is the target
microtubule
Functional organization of the gene
27. Epithelial cells
cytokeratin
Methotrexate
GFAP
Hydroxylation of which amino acids are attached to Glycine to form collagen
28. Inhibit formation of the initation complex and cause misreading of mRNA
Euchromatin
Aminoglycosides
Where do introns and exons stay
kinesin
29. Changed aaconservative - new aa is similar in chemical structure
Permanent cells
missense mutation
purines
degenerate or redundant
30. Microvilli - muscle contraction - cytokinesis - adhering juntions
Tetracyclines
Collagedn synthesis where?
Neurofilaments
actin and myosin
31. Immotile cilia due to a dyenin arm defect. Results in male nad female inferticility (sperm immotile) - bronchiectasis - and recurrent sinusisits - associated with situs inversus
dyenin
Kartageners syndrome
Which is the most and least abundant type of RNA
Cell cycle order
32. Vimentin - desmin - cytockeratin - glial fibrillary acid proteins - neurofilaments
intermediate filaments
Elastin is broken down by
What type of collagen is most affected in Ehlers Danlos
RNA polymerases in eukaryotes
33. 3 H bonds
C- G bond
microtubule
Chloramphenicol
Step one of RNA processing
34. Cleave terminal regions of procollagen to transform into insoluable tropocolagen
Step Three of RNA processing
Guanine has a
Example of permanent cells
Outside the cell what processing must be done in procolalgen
35. Methionine - which may be removed before translation is completed
In eukaryotes the starting amino acid is...
Alports syndrome
promoter
kinesin
36. Anti cancer - act on microtubules
Nucleotide excision repair
Vincristine/Vinblastine
Where do introns and exons stay
tRNA activation
37. Change resulting in early stop codon
nonsense
Silencer
Cyclins
Functional organization of the gene
38. Site of secretory protiens (mucus secreting goblet cells and antibody secreting cells)
Cyclin - CDK
purines
RNA polymerases in eukaryotes
Rough ER
39. Seals
desmin
Pyrimidines
DNA ligase
Cell cycle
40. 9+2 arrangement of microtubules -
Functional organization of the gene
Elastase is inhibited by
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
Cilia structure
41. A malfunction of mismatch repair (MUt L etc..)
Xeroderma pigmentosum
mRNA stop codons
Hereditary non polyposis colorectal cancer
Excocytosis of collagen
42. Anti breast cancer - acts on mts
step two of RNA processing
Associations of Ehlers Danlos
A- T
Paclitaxil
43. Prokaryotic only. Elongates leading strand by adding deoxynucleotides to the 3prime end. Elongates laggin strand. 3 prime to 5 prime exonuclease activity
DNA pol III
Cyclins
Step one of RNA processing
hydroxyurea
44. Unmethylated - newly synthesized string is recognized - mismatched nucleotides are removed and the gap is filled and resealed
Mismatch repair
Elongation
mRNA stop codons
The only histone not on the core
45. Anit helminth - act on microtubules
Gag on pure gold
DNA ligase
Cyclins
Mebendazole/thiabendazole
46. Enter G1 from G0 when stimulated Hepatocytes/lymphocytes
Stable (quiescent)
Cell cycle
Neurofilaments
Glycosolation
47. Substituting a pyramidine for a pyrimadine
Enhancers and silencer may be located_____
transition
Permanent cells
What does the hydroxylation of proline and lysine require
48. Splicing out of introns
Cell cycle
Ehlers Danlos
Tetracyclines
Step Three of RNA processing
49. More than 1 codon may code for the same amino acid
Enhancers and silencer may be located_____
degenerate or redundant
Rough ER
DNA pol III
50. Alpha 1 antitrypisn
Cilia structure
Non homologous end joining
Elastase is inhibited by
Where do introns and exons stay
Sorry!:) No result found.
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