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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Even 40S 60S =80S
Chloramphenicol
Introns
Oubain
Eukaroytes
2. Inhbits RNA pol II (found in death cap mushrooms)
Griseofulvin
alpha amintin
Which end of the nucleotide has the triphosphate
Neurofilaments
3. Asymmetric fluid bilayer - contains - cholesterol - phospholipids - sphingoplipids - glycolipids - and protiends
kinesin
Plasma membrane composition
microtubule
helicase
4. Specific glycosylases recognize and remove damaged bases - AP endonuclease cuts DNA at pyrimidne site - empty sugar is removed and the gap is filled and resealed
RNA processing in eukaryotes occurs
Rough ER
Hydroxylation of which amino acids are attached to Glycine to form collagen
Base excision repair
5. Codes for formyl methionine (f - Met)
universal
RNA polymerases in eukaryotes
AUG codes For what in prokaryotes
chromatin structure
6. (A - G) 2 rings Pure As Gold
Proteosomal degradation
Tumor Suppressors
actin and myosin
Purines
7. Unmethylated - newly synthesized string is recognized - mismatched nucleotides are removed and the gap is filled and resealed
Mismatch repair
Pyrimidines
Vincristine/Vinblastine
Type IV collagen is an important structural component of...
8. RNA polymerase I makes rRNA - RNA pol II makes mRNA - RNA pol III makes tRNA
RNA polymerases in eukaryotes
Proteosomal degradation
hydroxyurea
Tetracyclines
9. Anti breast cancer - acts on mts
mRNA start codons
Paclitaxil
Initial transcript without processing is known as
Cholchicine
10. Commonly results in dramatic decrease in amount of gene transcribed
6MP
Tumor Suppressors
Promoter mutation
commaless - non - overlapping
11. Strethchy protein within lungs - large artiers - elastic liaments - vocal cords - ligamenta flava)
Permanent cells
Elastin
step two of RNA processing
Post - translational modifications
12. Different exons can be combined to make nique protiens in different times
Alternate splicing
In eukaryotes the starting amino acid is...
Free ribosomes
Common amino acids in elastin
13. Vimentin - desmin - cytockeratin - glial fibrillary acid proteins - neurofilaments
Tropocollagen cross links between_____ to form____
Which end of the nucleotide has the triphosphate
Hereditary non polyposis colorectal cancer
intermediate filaments
14. Bind 50S blocking translocation
Digoxin (cardiac glycosides)
Macrolides
transition
commaless - non - overlapping
15. Inhibits the atpase which increases intracellular sodium which increases intracellular calcium increases cardiaccontractility
Aminoglycosides
Vincristine/Vinblastine
In eukaryotes the starting amino acid is...
Digoxin (cardiac glycosides)
16. Be So Totatally Cool Read Books (bOne - CarTWOlage - Threeticular - Type IV under the floor)
Higher the cholesterol or long saturated fatty acid content
Collagen
Methotrexate
tRNA Structure
17. Inhibits by binding to the potassium side
Oubain
Which is the most and least abundant type of RNA
silent mutation
Going APE
18. Scrutinizes aa before and after it binds to tRNA. If incorrect bond is hydrolyzed.
Paclitaxil
silent mutation
Aminoacylt - tRNA synthetase
C- G bond
19. Regulatory proteins that control cell cycle events; phase specific; activated CDKs
Cyclins
mRNA start codons
missense mutation
Tropocollagen cross links between_____ to form____
20. Uracil
step two of RNA processing
intermediate filaments
Deamination of cytosine makes
Mismatch repair
21. The 3 prime hydroxyl of the nascent chain is the target
DNA/RNA/Protein syntesis direction
cytokeratin
Cyclin - CDK
Which end of a growing DNA strand is the target
22. Introns stay In the nucleus whereas EXons EXit and are EXpressed
mRNA start codons
universal
Where do introns and exons stay
trimethoprim
23. Neuroglia
Example of permanent cells
helicase
Promoter mutation
GFAP
24. Changed aaconservative - new aa is similar in chemical structure
Sodium K ATPase
methionine is only encoded by
missense mutation
Enhancers and silencer may be located_____
25. Binds 50S blocking translocation
Clindamycin
Elastase is inhibited by
polyadenylation does/does not require a template
DNA topoisomerases
26. RER translation of collagen alpha chains (preprocollagen) usually Gly-X-Y
Collagedn synthesis where?
Kartageners syndrome
Elastin
Mebendazole/thiabendazole
27. Mutation in nucleotide excision repair Dry skin with melanoma and other cancers
Eukaroytes
Xeroderma pigmentosum
Neurofilaments
Step one of RNA processing
28. One codon AUG
Protein synthesis initiation
methionine is only encoded by
tRNA Structure
nucleotide
29. Create a nick in the helix to relieve supercoils created during replication
DNA/RNA/Protein syntesis direction
AUG codes For what in prokaryotes
Example of permanent cells
DNA topoisomerases
30. You glyucosolate hte pro - alpha chain lysine resudens and form procollagen (triple helix of alpha chains)
In eukaryotes the starting amino acid is...
Guanine has a
Glycosolation
Ehlers Danlos
31. 2 H bonds greater GC content greater melting point
intermediate filaments
A- T
Where do introns and exons stay
transversion
32. UGA - UAG - UAA
microtubule
Mismatch repair
Alports syndrome
mRNA stop codons
33. Blocks denovo purine synthesis
6MP
kinesin
Which is the most and least abundant type of RNA
Introns
34. Bind 30S subunit preventing attachment of aminoacyl - tRNA
microtubule
Tetracyclines
Protein synthesis is in which direction
Plasma membrane composition
35. The N to C
Protein synthesis is in which direction
Xeroderma pigmentosum
Exons
unambiguous
36. Genetic bone disorder (brittle bone disease) type 1 colalgen - fractures (during birth) 2) Blue sclerae 3) hearing loss 4) dental imperfections 1:10000 may be confused with child abuse
Cell cycle order
degenerate or redundant
Osteogenesis Imperfecta
Introns
37. 4 high enrgy bonds
Step Three of RNA processing
6MP
Eukaroytes
Total energy expenditure requirement for translocation
38. Responsible for the accuracy of amino acid selection
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
Cyclin - CDK
Initial transcript without processing is known as
Alports syndrome
39. No proofreading function but can initiate chains. RNA poymerase II opens DNA at promoter site
Plasma membrane composition
origin of replication
Proofreading function in eukaryotic RNA
chromatin structure
40. Enter G1 from G0 when stimulated Hepatocytes/lymphocytes
degenerate or redundant
Stable (quiescent)
Rough ER
origin of replication
41. Poly adenylation
nucleosid
CDKs
step two of RNA processing
DNA pol I
42. Particular sequnece in genomre where DNA replication begins. May be single (prokaryotes) or multiple (eukaryotes)
Protein synthesis is in which direction
Free ribosomes
Step one of RNA processing
origin of replication
43. Made from IMP precursor
purines
transversion
Collagedn synthesis where?
Guanine has a
44. Microtubule polymerization defect resulting in lowered phagocytosis. results in recurrent pyogenic infections - partial albinism and peripheral neuropathy
Tumor Suppressors
transversion
Chediak Higashi syndrome
Kartageners syndrome
45. More than 1 codon may code for the same amino acid
degenerate or redundant
pyrimadines
kinesin
Cyclin - CDK
46. Connective tissue
Clindamycin
Immunohistochemical stains vimentin
AUG codes For what in prokaryotes
Excocytosis of collagen
47. Aminoacyl - tRNA binds to A site 2) peptidyltransferase catalyzes peptide bond formation transfers growing polypeptie to amino acid in A site 3) ribosome advances 3 nucleotides toward the 3 prime end of RNA moving peptiydyl RNA to P site
nonsense
desmin
Elongation
universal
48. Activated by GTP hydrolosis initiation factors help assembel the 40 S ribosomal subunites with the initiatior tRNA and are released whent he mRNA and the ribosomal subunit assemple with the complex
Protein synthesis initiation
Glycosolation
unambiguous
Free ribosomes
49. Odd 30S plus 50 S=70S
Prokaryotes
Oubain
alpha amintin
single stranded binding proteinds
50. 1P (blocked by tetracycline)
Initial transcript without processing is known as
Loading tRNA on to ribosome energy requirement
Cholchicine
DNA ligase