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First Aid: Biochemistry Molecular

Instructions:
  • Answer 50 questions in 15 minutes.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Binds 50S blocking translocation






2. Prokaryotic only. Elongates leading strand by adding deoxynucleotides to the 3prime end. Elongates laggin strand. 3 prime to 5 prime exonuclease activity






3. UGA - UAG - UAA






4. VItamin C






5. Read froma fixed starting point as a continous sequenecs of bases






6. Muscle






7. Genetic code is conserved throughout evolution






8. Vimentin - desmin - cytockeratin - glial fibrillary acid proteins - neurofilaments






9. CCA AT 3 PRIME END






10. RNA polymerase I makes rRNA - RNA pol II makes mRNA - RNA pol III makes tRNA






11. Specific glycosylases recognize and remove damaged bases - AP endonuclease cuts DNA at pyrimidne site - empty sugar is removed and the gap is filled and resealed






12. Base+ribose+phosphate linked by a phosphodiester bond






13. Completed protein is released from ribosme through simple hydrolosis and dissociates






14. RER translation of collagen alpha chains (preprocollagen) usually Gly-X-Y






15. The 3 prime end






16. Close to - far from or even within (in an intron) the gene whose expression it regulates






17. No proofreading function but can initiate chains. RNA poymerase II opens DNA at promoter site






18. HS1 - HSB - H2 - H4






19. Inhibits by binding to the potassium side






20. Attachment of ubiquitin to defective proteinds to tag them for breakdown






21. Anterograde to microtubule






22. Anit helminth - act on microtubules






23. GTP






24. Inhibit DNA gyrase (specific prokaryotic topoisomerase)






25. Faulty collagen synthesis causing 1) hyperextensible skin 2) tendency to bleed 3) hypermobile joints






26. One codon AUG






27. Less condensed - transciptionally active=eu truly transcobed






28. Epithelial cells






29. H1






30. Site where negative regulators bind






31. Specific endonucleases release the oligonucleotide containing damaged bases. DNA polymerase and logase fill and resealt eh gap






32. Blocks denovo purine synthesis






33. Substituting a pyramidine for a pyrimadine






34. Even 40S 60S =80S






35. Contain the actual genetic information coding for protein






36. Inhibits the atpase which increases intracellular sodium which increases intracellular calcium increases cardiaccontractility






37. Methionine - which may be removed before translation is completed






38. The N to C






39. AD and AR- associated iwth joint dislocation - berry aneurysms - organ rupture






40. Activated by GTP hydrolosis initiation factors help assembel the 40 S ribosomal subunites with the initiatior tRNA and are released whent he mRNA and the ribosomal subunit assemple with the complex






41. Strethchy protein within lungs - large artiers - elastic liaments - vocal cords - ligamenta flava)






42. Unattached to any membrane; site of cytosolic and organeller prtoeins






43. Stretch of DNA that alters gene expression by binding transcription factors






44. Hydroxy proline and hydroxylysine






45. Phosphorylation - glycosloation - hyderoxylation






46. Anti breast cancer - acts on mts






47. The 3 prime hydroxyl of the nascent chain is the target






48. Tansport cellular cargo toward opposite ends of microtubule tracks






49. ATP






50. ATP ase that links peripheral 9 doublets and causes bending of cilium by differential sliding of doublets







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