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Test your basic knowledge |
First Aid: Biochemistry Molecular
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Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
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study here
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Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. A site - incoming aminoacyl tRNA - Psite accomodates growing Peptide - E site holds EmplytRNA as it exits
What does the hydroxylation of proline and lysine require
Plasma membrane composition
Going APE
capped and tail transcript is called
2. Bind 50S blocking translocation
missense mutation
Macrolides
Prokaryote RNA pol
Enhancer
3. Lysine/hydroxylysine and combines to form collagen
What type of collagen is most affected in Ehlers Danlos
Stable (quiescent)
Tropocollagen cross links between_____ to form____
Griseofulvin
4. Exocytose procollagen into extracellylar sace
Excocytosis of collagen
Prokaryote RNA pol
methionine is only encoded by
Cell cycle order
5. Three amino acids necessary for purine synthesis= glutamine - aspartate and glycine
chromatin structure
Mebendazole/thiabendazole
Gag on pure gold
Which end of the nucleotide has the triphosphate
6. Condensed - transciptionally inactive HC- Highly condensed
Higher the cholesterol or long saturated fatty acid content
Protein synthesis is in which direction
Guanine has a
Heterochromatin
7. Genetic bone disorder (brittle bone disease) type 1 colalgen - fractures (during birth) 2) Blue sclerae 3) hearing loss 4) dental imperfections 1:10000 may be confused with child abuse
DNA topoisomerases
Common amino acids in elastin
Osteogenesis Imperfecta
mRNA stop codons
8. Nucleotide excision repair - Base Excision repair - Mismath repair
Single Strand DNA Repair types
Total energy expenditure requirement for translocation
Associations of Ehlers Danlos
Proofreading function in eukaryotic RNA
9. Prokaryotic only. Elongates leading strand by adding deoxynucleotides to the 3prime end. Elongates laggin strand. 3 prime to 5 prime exonuclease activity
DNA ligase
Gag on pure gold
the tRNA- amino acid bond
DNA pol III
10. Anti cancer - act on microtubules
Vincristine/Vinblastine
Chediak Higashi syndrome
Enhancers and silencer may be located_____
Rough ER
11. Substituting a purine for a pyrimdine or vice versa
transversion
microtubule
Silencer
Double Strand DNA repair
12. MRNA
commaless - non - overlapping
capped and tail transcript is called
DNA topoisomerases
The only histone not on the core
13. Proline - glycine
Exons
Common amino acids in elastin
Step Three of RNA processing
Which end of the nucleotide has the triphosphate
14. Intervening noncoding segments of DNA
Base excision repair
Introns
Cholchicine
Hereditary non polyposis colorectal cancer
15. Inhibit formation of the initation complex and cause misreading of mRNA
What ties teh nucleosome together
Osteogenesis Imperfecta
Non homologous end joining
Aminoglycosides
16. Aminoacyl - tRNA binds to A site 2) peptidyltransferase catalyzes peptide bond formation transfers growing polypeptie to amino acid in A site 3) ribosome advances 3 nucleotides toward the 3 prime end of RNA moving peptiydyl RNA to P site
missense mutation
Mismatch repair
Elongation
Single Strand DNA Repair types
17. Unwinds DNA template at replication fork
Translocation
Functional organization of the gene
Order of mitosis
helicase
18. Unmethylated - newly synthesized string is recognized - mismatched nucleotides are removed and the gap is filled and resealed
CDKs
Pyrimidines
Post - translational modifications
Mismatch repair
19. The 5prime end (energy for the bond)
Osteogenesis Imperfecta
pyrimadines
Which end of the nucleotide has the triphosphate
tRNA
20. Never go to Go divide rapidly with short G1 bone marrow - gut epithelium - skin - hair follicles
Kartageners syndrome
Labile
What does the hydroxylation of proline and lysine require
Associations of Ehlers Danlos
21. P53 and RB normally inhibit g1 to S progression
Xeroderma pigmentosum
Rough ER
step two of RNA processing
Tumor Suppressors
22. The 3 prime end
Which end of the tRNA is the amino acid bound to?
Macrolides
mRNA stop codons
tRNA aminoacylation
23. In the nucleus after transcitpion and only processed RNA is transporte out of the nucleus
Hydroxylation of which amino acids are attached to Glycine to form collagen
RNA processing in eukaryotes occurs
Step Three of RNA processing
microtubule
24. The 3 prime hydroxyl of the nascent chain is the target
DNA/RNA/Protein syntesis direction
mRNA stop codons
Which end of a growing DNA strand is the target
Single Strand DNA Repair types
25. Xlinked recessive IV collagen bm - kidney - ear and eye -- nephritis and defness ocular disturbances
origin of replication
Hydroxylation of which amino acids are attached to Glycine to form collagen
Alports syndrome
Primase
26. Methionine - which may be removed before translation is completed
intermediate filaments
Nucleotide excision repair
In eukaryotes the starting amino acid is...
mRNA stop codons
27. 3 sodium out for 2 potassium in (nout - kin)takes 1 atp and the machine is phosphorylated during the machine cycle
dyenin
Common amino acids in elastin
Sodium K ATPase
commaless - non - overlapping
28. Y shaped region along DNA template where leading and lagging strands are syntehsized
Replication fork
mRNA start codons
Plasma membrane composition
DNA pol III
29. HS1 - HSB - H2 - H4
Which end of the tRNA is the amino acid bound to?
histone octamer names
Protein synthesis initiation
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
30. Type III
Going APE
Covalent alterations
What type of collagen is most affected in Ehlers Danlos
helicase
31. Genetic code is conserved throughout evolution
Ehlers Danlos
Aminoglycosides
universal
desmin
32. Mutation in nucleotide excision repair Dry skin with melanoma and other cancers
Step one of RNA processing
Xeroderma pigmentosum
Hereditary non polyposis colorectal cancer
Thymine has a
33. Change resulting in early stop codon
nonsense
Excocytosis of collagen
Introns
Which end of the tRNA is the amino acid bound to?
34. Changed aaconservative - new aa is similar in chemical structure
capped and tail transcript is called
missense mutation
Alternate splicing
Smooth ER
35. Attachment of ubiquitin to defective proteinds to tag them for breakdown
Proteosomal degradation
Cell cycle order
Step Three of RNA processing
Oubain
36. RNA polymerase I makes rRNA - RNA pol II makes mRNA - RNA pol III makes tRNA
pyrimadines
Macrolides
RNA polymerases in eukaryotes
Double Strand DNA repair
37. Scrutinizes aa before and after it binds to tRNA. If incorrect bond is hydrolyzed.
Post - translational modifications
Example of permanent cells
Macrolides
Aminoacylt - tRNA synthetase
38. Anti breast cancer - acts on mts
single stranded binding proteinds
mRNA start codons
Pyrimidines
Paclitaxil
39. Contain the actual genetic information coding for protein
Exons
Which end of a growing DNA strand is the target
C- G bond
Which is the most and least abundant type of RNA
40. Even 40S 60S =80S
Deamination of cytosine makes
Eukaroytes
Introns
dyenin
41. Tansport cellular cargo toward opposite ends of microtubule tracks
Mebendazole/thiabendazole
Thymine has a
Alports syndrome
Molecular motor protiesn
42. Anit helminth - act on microtubules
RNA polymerases in eukaryotes
AUG codes For what in prokaryotes
Mebendazole/thiabendazole
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
43. Particular sequnece in genomre where DNA replication begins. May be single (prokaryotes) or multiple (eukaryotes)
Griseofulvin
White codon is at the 3 prime end of a tRNA
DNA ligase
origin of replication
44. Inhibits the atpase which increases intracellular sodium which increases intracellular calcium increases cardiaccontractility
Step one of RNA processing
Digoxin (cardiac glycosides)
actin and myosin
Cell cycle
45. Ketone
Guanine has a
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
Smooth ER
Steps in splicing
46. Retrograde to microtubules
Replication fork
Outside the cell what processing must be done in procolalgen
Step Three of RNA processing
dyenin
47. Made from IMP precursor
Methotrexate
purines
capped and tail transcript is called
Eukaroytes
48. Less condensed - transciptionally active=eu truly transcobed
microtubule
Pyrimidines
Oubain
Euchromatin
49. Accurate base pairing is required only in the first 2 nucleotide positions of an mRNA so codons differing ht e3rd wobble psoition may code for the same tRNA/amino acid code
tRNA
Post - translational modifications
Cell cycle
Higher the cholesterol or long saturated fatty acid content
50. Inhibits thymidylate synthase down thymine
microtubule
Double Strand DNA repair
polyadenylation does/does not require a template
5FU
Sorry!:) No result found.
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