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First Aid: Biochemistry Molecular

Instructions:
  • Answer 50 questions in 15 minutes.
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  • Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. HS1 - HSB - H2 - H4






2. 75-90 nucleotides - 2ary structure cloverleaf form anticodon end is opposite 3 prime aminoacyl end






3. G1 - S - G2 - Mitosis






4. Poly adenylation






5. Prevents stranges from reannealing






6. Hn RNA






7. Prokaryotic only. Elongates leading strand by adding deoxynucleotides to the 3prime end. Elongates laggin strand. 3 prime to 5 prime exonuclease activity






8. Epithelial cells






9. Site where negative regulators bind






10. Cilia - glagella - mitotic spindle - neurons - centrioles






11. Xlinked recessive IV collagen bm - kidney - ear and eye -- nephritis and defness ocular disturbances






12. Bm - kidney - ears and eyes






13. VItamin C






14. Microtubule polymerization defect resulting in lowered phagocytosis. results in recurrent pyogenic infections - partial albinism and peripheral neuropathy






15. ATP ase that links peripheral 9 doublets and causes bending of cilium by differential sliding of doublets






16. Neurons






17. Nucleotide excision repair - Base Excision repair - Mismath repair






18. Phosphorylation - glycosloation - hyderoxylation






19. P53 and RB normally inhibit g1 to S progression






20. Blocks denovo purine synthesis






21. Inhibit DNA gyrase (specific prokaryotic topoisomerase)






22. Each codon specifies only 1 amino acid






23. Brings together 2 ends of DNA fragments no requirement for homology






24. Methyl THYmine has a meTHYl






25. A site - incoming aminoacyl tRNA - Psite accomodates growing Peptide - E site holds EmplytRNA as it exits






26. Capping on 5 prime end (7 methylguanosine) -






27. Same aa often base change in 3rd position of codon






28. 1 RNA polymerase (multisubunite complex) makes all 3 kinds of RNA






29. Type III






30. Binds 50S blocking translocation






31. Anterograde to microtubule






32. Inhibits thymidylate synthase down thymine






33. Rampant - Massive - TIny rRNA is most common - then mRNA and then tRNA






34. H1






35. ATP






36. Site of dteroid synthesis and detoxification of druigs and poisons (liver hepatocytes and steroid horomore adrenal cortex)






37. Made from orogate precuror with PRPP added later






38. Unwinds DNA template at replication fork






39. Greater melting temperature lower fluidity






40. 1P (blocked by tetracycline)






41. Attachment of ubiquitin to defective proteinds to tag them for breakdown






42. Ketone






43. A malfunction of mismatch repair (MUt L etc..)






44. Specific glycosylases recognize and remove damaged bases - AP endonuclease cuts DNA at pyrimidne site - empty sugar is removed and the gap is filled and resealed






45. H1 string






46. Inhibits 50S peptidyl transferase






47. Genetic bone disorder (brittle bone disease) type 1 colalgen - fractures (during birth) 2) Blue sclerae 3) hearing loss 4) dental imperfections 1:10000 may be confused with child abuse






48. Negatively charged DNA loops twice around histone octamers create a nucloesome bead.






49. Codes for formyl methionine (f - Met)






50. Contain the actual genetic information coding for protein







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