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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. 1P blocked by chloramphenicaol and macrolide
Exons
Enhancers and silencer may be located_____
Translocation
What does the hydroxylation of proline and lysine require
2. Promoter - enhancer - promoter - TATA- transcription initiation site - coding region (including exons and introns) and then the AATAAA
Functional organization of the gene
Purines
microtubule
Replication fork
3. Strethchy protein within lungs - large artiers - elastic liaments - vocal cords - ligamenta flava)
Initial transcript without processing is known as
Elastin
mRNA is syntehsized in which direction?
Macrolides
4. Alpha 1 antitrypisn
Elastase is inhibited by
Cholchicine
Which is the most and least abundant type of RNA
Promoter mutation
5. No proofreading function but can initiate chains. RNA poymerase II opens DNA at promoter site
Tropocollagen cross links between_____ to form____
Cholchicine
Silencer
Proofreading function in eukaryotic RNA
6. Cyclin depndent kinases; consituative and inactive
CDKs
transition
Proofreading function in eukaryotic RNA
tRNA aminoacylation
7. Bind 30S subunit preventing attachment of aminoacyl - tRNA
pyrimadines
transversion
Tetracyclines
Tropocollagen cross links between_____ to form____
8. Genetic code is conserved throughout evolution
Alternate splicing
unambiguous
universal
chromatin structure
9. Read froma fixed starting point as a continous sequenecs of bases
Rough ER
commaless - non - overlapping
Type IV collagen is an important structural component of...
Which end of a growing DNA strand is the target
10. Aminoacyl - tRNA binds to A site 2) peptidyltransferase catalyzes peptide bond formation transfers growing polypeptie to amino acid in A site 3) ribosome advances 3 nucleotides toward the 3 prime end of RNA moving peptiydyl RNA to P site
CDKs
Aminoacylt - tRNA synthetase
Elongation
Alports syndrome
11. H1
The only histone not on the core
promoter
Labile
6MP
12. Epithelial cells
Which end of a growing DNA strand is the target
cytokeratin
Osteogenesis Imperfecta
Griseofulvin
13. Rampant - Massive - TIny rRNA is most common - then mRNA and then tRNA
mRNA start codons
Which is the most and least abundant type of RNA
Step Three of RNA processing
Post - translational modifications
14. 4 high enrgy bonds
Vincristine/Vinblastine
Methotrexate
DNA/RNA/Protein syntesis direction
Total energy expenditure requirement for translocation
15. One codon AUG
methionine is only encoded by
Chloramphenicol
Primase
alpha amintin
16. Scrutinizes aa before and after it binds to tRNA. If incorrect bond is hydrolyzed.
Step Three of RNA processing
CDKs
desmin
Aminoacylt - tRNA synthetase
17. Xlinked recessive IV collagen bm - kidney - ear and eye -- nephritis and defness ocular disturbances
Going APE
Hereditary non polyposis colorectal cancer
Tropocollagen cross links between_____ to form____
Alports syndrome
18. Antifungal - act on microtubules
Smooth ER
Griseofulvin
Promoter mutation
Introns
19. Binds 50S blocking translocation
Primase
Outside the cell what processing must be done in procolalgen
Clindamycin
degenerate or redundant
20. Inhibit formation of the initation complex and cause misreading of mRNA
transition
5FU
Type IV collagen is an important structural component of...
Aminoglycosides
21. Elastase
Excocytosis of collagen
Thymine has a
Elastin is broken down by
purines
22. Microvilli - muscle contraction - cytokinesis - adhering juntions
actin and myosin
frame shift
Cilia structure
Cell cycle
23. Cilia - glagella - mitotic spindle - neurons - centrioles
microtubule
Collagen
Elastin is broken down by
A- T
24. RER translation of collagen alpha chains (preprocollagen) usually Gly-X-Y
kinesin
Type IV collagen is an important structural component of...
Collagedn synthesis where?
White codon is at the 3 prime end of a tRNA
25. Activated by GTP hydrolosis initiation factors help assembel the 40 S ribosomal subunites with the initiatior tRNA and are released whent he mRNA and the ribosomal subunit assemple with the complex
polyadenylation does/does not require a template
transversion
Deamination of cytosine makes
Protein synthesis initiation
26. Changed aaconservative - new aa is similar in chemical structure
missense mutation
histone octamer names
DNA pol III
Kartageners syndrome
27. GTP
Prokaryote RNA pol
Total energy expenditure requirement for translocation
Aminoglycosides
tRNA gripping and going places
28. 3 H bonds
helicase
Termination
6MP
C- G bond
29. Create a nick in the helix to relieve supercoils created during replication
Which end of a growing DNA strand is the target
DNA topoisomerases
Double Strand DNA repair
Covalent alterations
30. UGA - UAG - UAA
Plasma membrane composition
Cell cycle order
mRNA stop codons
Protein synthesis is in which direction
31. Methyl THYmine has a meTHYl
Covalent alterations
Thymine has a
RNA polymerases in eukaryotes
The only histone not on the core
32. Ketone
Heterochromatin
Step Three of RNA processing
Outside the cell what processing must be done in procolalgen
Guanine has a
33. Muscle
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
Cell cycle
Initial transcript without processing is known as
desmin
34. Inhbits RNA pol II (found in death cap mushrooms)
intermediate filaments
pyrimadines
Elastase is inhibited by
alpha amintin
35. Inhibit DNA gyrase (specific prokaryotic topoisomerase)
silent mutation
Fluoroquinolones
origin of replication
Thymine has a
36. Made from IMP precursor
In eukaryotes the starting amino acid is...
Methotrexate
Smooth ER
purines
37. Prokaryotic only. Degrades RNA primer and fills in the gap with DNA (5 prime to 3 prime exonuclease)
RNA processing in eukaryotes occurs
DNA pol I
Type IV collagen is an important structural component of...
Smooth ER
38. Must be both activated and inactivated for cell cycle to progress
CDKs
Glycosolation
Cyclin - CDK
Oubain
39. CUT 1 ring Cut the Py
tRNA gripping and going places
Pyrimidines
methionine is only encoded by
Sodium K ATPase
40. Anterograde to microtubule
kinesin
Guanine has a
tRNA activation
nucleotide
41. Specific glycosylases recognize and remove damaged bases - AP endonuclease cuts DNA at pyrimidne site - empty sugar is removed and the gap is filled and resealed
Base excision repair
Associations of Ehlers Danlos
transversion
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
42. Inhibits thymidylate synthase down thymine
tRNA aminoacylation
5FU
universal
Rough ER
43. Vimentin - desmin - cytockeratin - glial fibrillary acid proteins - neurofilaments
Glycosolation
intermediate filaments
kinesin
cytokeratin
44. Substituting a pyramidine for a pyrimadine
RNA polymerases in eukaryotes
nonsense
transition
Common amino acids in elastin
45. H1 string
Paclitaxil
What ties teh nucleosome together
Sodium K ATPase
mRNA stop codons
46. A malfunction of mismatch repair (MUt L etc..)
Hereditary non polyposis colorectal cancer
desmin
Where do introns and exons stay
DNA topoisomerases
47. Unmethylated - newly synthesized string is recognized - mismatched nucleotides are removed and the gap is filled and resealed
Loading tRNA on to ribosome energy requirement
the tRNA- amino acid bond
Mismatch repair
Hereditary non polyposis colorectal cancer
48. Attachment of ubiquitin to defective proteinds to tag them for breakdown
Elastin is broken down by
Proteosomal degradation
Chloramphenicol
Collagedn synthesis where?
49. Inhibits the atpase which increases intracellular sodium which increases intracellular calcium increases cardiaccontractility
Digoxin (cardiac glycosides)
Where do introns and exons stay
Alports syndrome
Nucleotide excision repair
50. Checkpoints control transition between phases of cell cycle. regulated by cyclins - CDKs and tumor suppressors. Mitosis (shortest phse)
unambiguous
Cell cycle
Tropocollagen cross links between_____ to form____
histone octamer names