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Test your basic knowledge |
First Aid: Biochemistry Molecular
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Subjects
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health-sciences
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first-aid
Instructions:
Answer 50 questions in 15 minutes.
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study here
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Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Accurate base pairing is required only in the first 2 nucleotide positions of an mRNA so codons differing ht e3rd wobble psoition may code for the same tRNA/amino acid code
Protein synthesis is in which direction
Sodium K ATPase
Alports syndrome
tRNA
2. Made from IMP precursor
White codon is at the 3 prime end of a tRNA
Vincristine/Vinblastine
Permanent cells
purines
3. Cylindrical structure composed of helical array of plymerized dimers of alpha and beta tubulin - flagella - cilia - mitotic spindle - grows slowly collapses quickly
single stranded binding proteinds
Exons
Euchromatin
microtubule
4. Prophas - metaphase - anaphase telophase
Order of mitosis
Elastase is inhibited by
Covalent alterations
Plasma membrane composition
5. Unattached to any membrane; site of cytosolic and organeller prtoeins
mRNA is syntehsized in which direction?
Free ribosomes
Cyclin - CDK
Step Three of RNA processing
6. Attachment of ubiquitin to defective proteinds to tag them for breakdown
Promoter mutation
Proteosomal degradation
desmin
single stranded binding proteinds
7. Change resulting in early stop codon
tRNA Structure
origin of replication
alpha amintin
nonsense
8. Inhibits bacterials dihydrofolate reducatese down thymine
trimethoprim
Immunohistochemical stains vimentin
Cyclin - CDK
Which is the most and least abundant type of RNA
9. Mutation in nucleotide excision repair Dry skin with melanoma and other cancers
AUG codes For what in prokaryotes
Associations of Ehlers Danlos
desmin
Xeroderma pigmentosum
10. Has enough energy to created the peptide bond
Neurofilaments
the tRNA- amino acid bond
mRNA start codons
C- G bond
11. Create a nick in the helix to relieve supercoils created during replication
trimethoprim
DNA topoisomerases
Aminoglycosides
Tropocollagen cross links between_____ to form____
12. Asymmetric fluid bilayer - contains - cholesterol - phospholipids - sphingoplipids - glycolipids - and protiends
Cell cycle
C- G bond
unambiguous
Plasma membrane composition
13. Even 40S 60S =80S
Eukaroytes
Silencer
Enhancer
trimethoprim
14. UGA - UAG - UAA
Higher the cholesterol or long saturated fatty acid content
mRNA stop codons
Molecular motor protiesn
Prokaryote RNA pol
15. 3 H bonds
Elastin is broken down by
C- G bond
What does the hydroxylation of proline and lysine require
Elastin
16. Neuroglia
single stranded binding proteinds
Base excision repair
mRNA start codons
GFAP
17. Proline - glycine
Tetracyclines
Common amino acids in elastin
Elastase is inhibited by
Molecular motor protiesn
18. Must be both activated and inactivated for cell cycle to progress
Cyclin - CDK
Nucleotide excision repair
Sodium K ATPase
DNA pol I
19. Faulty collagen synthesis causing 1) hyperextensible skin 2) tendency to bleed 3) hypermobile joints
Ehlers Danlos
Outside the cell what processing must be done in procolalgen
Promoter mutation
mRNA is syntehsized in which direction?
20. Greater melting temperature lower fluidity
Alports syndrome
kinesin
methionine is only encoded by
Higher the cholesterol or long saturated fatty acid content
21. P53 and RB normally inhibit g1 to S progression
Tumor Suppressors
What does the hydroxylation of proline and lysine require
Eukaroytes
A- T
22. 4 high enrgy bonds
Mismatch repair
silent mutation
Total energy expenditure requirement for translocation
Which end of the nucleotide has the triphosphate
23. Anti breast cancer - acts on mts
transversion
Functional organization of the gene
Mismatch repair
Paclitaxil
24. ATP- AMP (2 phosphoanhydride bonds)
Tumor Suppressors
degenerate or redundant
tRNA aminoacylation
mRNA stop codons
25. Anterograde to microtubule
Guanine has a
tRNA aminoacylation
kinesin
origin of replication
26. Regulatory proteins that control cell cycle events; phase specific; activated CDKs
DNA pol III
Cyclins
Kartageners syndrome
Hydroxylation of which amino acids are attached to Glycine to form collagen
27. Prokaryotic only. Degrades RNA primer and fills in the gap with DNA (5 prime to 3 prime exonuclease)
Cyclin - CDK
Enhancers and silencer may be located_____
GFAP
DNA pol I
28. Anti cancer - act on microtubules
6MP
Euchromatin
Vincristine/Vinblastine
Pyrimidines
29. Contain the actual genetic information coding for protein
commaless - non - overlapping
Exons
desmin
Elastin is broken down by
30. Retrograde to microtubules
Elastin is broken down by
tRNA gripping and going places
Chediak Higashi syndrome
dyenin
31. Particular sequnece in genomre where DNA replication begins. May be single (prokaryotes) or multiple (eukaryotes)
origin of replication
Protein synthesis is in which direction
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
actin and myosin
32. Less condensed - transciptionally active=eu truly transcobed
White codon is at the 3 prime end of a tRNA
What does the hydroxylation of proline and lysine require
DNA topoisomerases
Euchromatin
33. Never go to Go divide rapidly with short G1 bone marrow - gut epithelium - skin - hair follicles
Permanent cells
Hereditary non polyposis colorectal cancer
Labile
5FU
34. Microtubule polymerization defect resulting in lowered phagocytosis. results in recurrent pyogenic infections - partial albinism and peripheral neuropathy
origin of replication
Chediak Higashi syndrome
Elastase is inhibited by
Vincristine/Vinblastine
35. Inhibits dihydrofolate reductase down thymine
Pyrimidines
methionine is only encoded by
Methotrexate
The only histone not on the core
36. Antigout - acts on mts
Cholchicine
In eukaryotes the starting amino acid is...
Digoxin (cardiac glycosides)
intermediate filaments
37. Antifungal - act on microtubules
intermediate filaments
degenerate or redundant
Cell cycle order
Griseofulvin
38. In the nucleus after transcitpion and only processed RNA is transporte out of the nucleus
Aminoglycosides
Alports syndrome
RNA processing in eukaryotes occurs
Cell cycle order
39. Elastase
Elastin is broken down by
Chediak Higashi syndrome
Tumor Suppressors
Introns
40. H1 string
microtubule
What ties teh nucleosome together
kinesin
Which end of the tRNA is the amino acid bound to?
41. HS1 - HSB - H2 - H4
Chediak Higashi syndrome
nucleotide
histone octamer names
Covalent alterations
42. Seals
Aminoacylt - tRNA synthetase
Tropocollagen cross links between_____ to form____
Chloramphenicol
DNA ligase
43. ATP
capped and tail transcript is called
Paclitaxil
tRNA activation
Tropocollagen cross links between_____ to form____
44. G1 - S - G2 - Mitosis
Axonemal dyenin
Cell cycle order
What ties teh nucleosome together
Which end of a growing DNA strand is the target
45. Neurons - skeletal - and cardiac muscle - RBCs
DNA topoisomerases
Axonemal dyenin
Example of permanent cells
transversion
46. Epithelial cells
Collagen
5FU
Free ribosomes
cytokeratin
47. 2 H bonds greater GC content greater melting point
Enhancer
Mebendazole/thiabendazole
White codon is at the 3 prime end of a tRNA
A- T
48. Completed protein is released from ribosme through simple hydrolosis and dissociates
capped and tail transcript is called
Cyclins
Termination
AUG codes For what in prokaryotes
49. VItamin C
Higher the cholesterol or long saturated fatty acid content
What does the hydroxylation of proline and lysine require
desmin
Which end of a growing DNA strand is the target
50. Anit helminth - act on microtubules
Introns
Aminoglycosides
GFAP
Mebendazole/thiabendazole
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