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Test your basic knowledge |
First Aid: Biochemistry Molecular
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Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
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study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. HS1 - HSB - H2 - H4
Digoxin (cardiac glycosides)
Kartageners syndrome
nucleosid
histone octamer names
2. 75-90 nucleotides - 2ary structure cloverleaf form anticodon end is opposite 3 prime aminoacyl end
nucleosid
Alternate splicing
Fluoroquinolones
tRNA Structure
3. G1 - S - G2 - Mitosis
A- T
Cell cycle order
Hydroxylation of which amino acids are attached to Glycine to form collagen
methionine is only encoded by
4. Poly adenylation
step two of RNA processing
5FU
purines
DNA pol III
5. Prevents stranges from reannealing
Which is the most and least abundant type of RNA
Type IV collagen is an important structural component of...
single stranded binding proteinds
transversion
6. Hn RNA
Prokaryotes
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
Cyclins
Initial transcript without processing is known as
7. Prokaryotic only. Elongates leading strand by adding deoxynucleotides to the 3prime end. Elongates laggin strand. 3 prime to 5 prime exonuclease activity
Plasma membrane composition
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
Steps in splicing
DNA pol III
8. Epithelial cells
Exons
cytokeratin
Nucleotide excision repair
Cholchicine
9. Site where negative regulators bind
Silencer
Proofreading function in eukaryotic RNA
cytokeratin
silent mutation
10. Cilia - glagella - mitotic spindle - neurons - centrioles
Elastin is broken down by
What ties teh nucleosome together
Which is the most and least abundant type of RNA
microtubule
11. Xlinked recessive IV collagen bm - kidney - ear and eye -- nephritis and defness ocular disturbances
Rough ER
Alports syndrome
Collagen
unambiguous
12. Bm - kidney - ears and eyes
Purines
Type IV collagen is an important structural component of...
Gag on pure gold
Osteogenesis Imperfecta
13. VItamin C
Exons
DNA pol I
The only histone not on the core
What does the hydroxylation of proline and lysine require
14. Microtubule polymerization defect resulting in lowered phagocytosis. results in recurrent pyogenic infections - partial albinism and peripheral neuropathy
Example of permanent cells
Chediak Higashi syndrome
tRNA
RNA processing in eukaryotes occurs
15. ATP ase that links peripheral 9 doublets and causes bending of cilium by differential sliding of doublets
microtubule
Single Strand DNA Repair types
Axonemal dyenin
Silencer
16. Neurons
DNA pol I
Neurofilaments
polyadenylation does/does not require a template
RNA processing in eukaryotes occurs
17. Nucleotide excision repair - Base Excision repair - Mismath repair
Free ribosomes
Single Strand DNA Repair types
Mismatch repair
microtubule
18. Phosphorylation - glycosloation - hyderoxylation
universal
single stranded binding proteinds
Covalent alterations
Tumor Suppressors
19. P53 and RB normally inhibit g1 to S progression
Elastin is broken down by
Tumor Suppressors
DNA pol III
Chloramphenicol
20. Blocks denovo purine synthesis
Cyclins
Total energy expenditure requirement for translocation
6MP
Fluoroquinolones
21. Inhibit DNA gyrase (specific prokaryotic topoisomerase)
mRNA start codons
White codon is at the 3 prime end of a tRNA
Fluoroquinolones
microtubule
22. Each codon specifies only 1 amino acid
Cyclins
unambiguous
Permanent cells
promoter
23. Brings together 2 ends of DNA fragments no requirement for homology
tRNA
Non homologous end joining
Methotrexate
transversion
24. Methyl THYmine has a meTHYl
desmin
Thymine has a
5FU
Cyclins
25. A site - incoming aminoacyl tRNA - Psite accomodates growing Peptide - E site holds EmplytRNA as it exits
Alports syndrome
Chediak Higashi syndrome
5FU
Going APE
26. Capping on 5 prime end (7 methylguanosine) -
Step one of RNA processing
unambiguous
Associations of Ehlers Danlos
GFAP
27. Same aa often base change in 3rd position of codon
Cholchicine
tRNA Structure
silent mutation
pyrimadines
28. 1 RNA polymerase (multisubunite complex) makes all 3 kinds of RNA
Euchromatin
Going APE
Prokaryote RNA pol
Rough ER
29. Type III
Tetracyclines
DNA pol III
histone octamer names
What type of collagen is most affected in Ehlers Danlos
30. Binds 50S blocking translocation
Molecular motor protiesn
Higher the cholesterol or long saturated fatty acid content
Clindamycin
Collagedn synthesis where?
31. Anterograde to microtubule
A- T
Prokaryotes
Euchromatin
kinesin
32. Inhibits thymidylate synthase down thymine
5FU
6MP
DNA topoisomerases
C- G bond
33. Rampant - Massive - TIny rRNA is most common - then mRNA and then tRNA
Gag on pure gold
Termination
Which is the most and least abundant type of RNA
Collagen
34. H1
Post - translational modifications
Outside the cell what processing must be done in procolalgen
The only histone not on the core
Labile
35. ATP
Enhancers and silencer may be located_____
Kartageners syndrome
Pyrimidines
tRNA activation
36. Site of dteroid synthesis and detoxification of druigs and poisons (liver hepatocytes and steroid horomore adrenal cortex)
Kartageners syndrome
Smooth ER
actin and myosin
Outside the cell what processing must be done in procolalgen
37. Made from orogate precuror with PRPP added later
A- T
pyrimadines
In eukaryotes the starting amino acid is...
Cyclins
38. Unwinds DNA template at replication fork
Proofreading function in eukaryotic RNA
helicase
dyenin
6MP
39. Greater melting temperature lower fluidity
Higher the cholesterol or long saturated fatty acid content
Exons
Permanent cells
transversion
40. 1P (blocked by tetracycline)
Tropocollagen cross links between_____ to form____
Loading tRNA on to ribosome energy requirement
Cyclins
The only histone not on the core
41. Attachment of ubiquitin to defective proteinds to tag them for breakdown
tRNA activation
Total energy expenditure requirement for translocation
Thymine has a
Proteosomal degradation
42. Ketone
Chloramphenicol
AUG codes For what in prokaryotes
Mismatch repair
Guanine has a
43. A malfunction of mismatch repair (MUt L etc..)
Neurofilaments
cytokeratin
Hereditary non polyposis colorectal cancer
polyadenylation does/does not require a template
44. Specific glycosylases recognize and remove damaged bases - AP endonuclease cuts DNA at pyrimidne site - empty sugar is removed and the gap is filled and resealed
Base excision repair
Loading tRNA on to ribosome energy requirement
Higher the cholesterol or long saturated fatty acid content
Gag on pure gold
45. H1 string
Griseofulvin
What ties teh nucleosome together
Sodium K ATPase
Alports syndrome
46. Inhibits 50S peptidyl transferase
Proofreading function in eukaryotic RNA
Double Strand DNA repair
CDKs
Chloramphenicol
47. Genetic bone disorder (brittle bone disease) type 1 colalgen - fractures (during birth) 2) Blue sclerae 3) hearing loss 4) dental imperfections 1:10000 may be confused with child abuse
Post - translational modifications
Proofreading function in eukaryotic RNA
Osteogenesis Imperfecta
DNA topoisomerases
48. Negatively charged DNA loops twice around histone octamers create a nucloesome bead.
tRNA aminoacylation
the tRNA- amino acid bond
chromatin structure
Total energy expenditure requirement for translocation
49. Codes for formyl methionine (f - Met)
Chediak Higashi syndrome
AUG codes For what in prokaryotes
hydroxyurea
Double Strand DNA repair
50. Contain the actual genetic information coding for protein
Exons
Paclitaxil
What does the hydroxylation of proline and lysine require
Silencer
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