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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Nucleotide excision repair - Base Excision repair - Mismath repair
mRNA start codons
Permanent cells
trimethoprim
Single Strand DNA Repair types
2. Elastase
Elastin is broken down by
Silencer
Promoter mutation
alpha amintin
3. Three amino acids necessary for purine synthesis= glutamine - aspartate and glycine
Gag on pure gold
actin and myosin
Proteosomal degradation
Fluoroquinolones
4. Tansport cellular cargo toward opposite ends of microtubule tracks
Molecular motor protiesn
tRNA Structure
Going APE
polyadenylation does/does not require a template
5. Intervening noncoding segments of DNA
Protein synthesis initiation
Introns
microtubule
histone octamer names
6. Scrutinizes aa before and after it binds to tRNA. If incorrect bond is hydrolyzed.
tRNA aminoacylation
tRNA activation
Which end of the nucleotide has the triphosphate
Aminoacylt - tRNA synthetase
7. Never go to Go divide rapidly with short G1 bone marrow - gut epithelium - skin - hair follicles
Labile
A- T
Step one of RNA processing
pyrimadines
8. Base+ribose+phosphate linked by a phosphodiester bond
6MP
nucleotide
Cyclins
Guanine has a
9. Particular sequnece in genomre where DNA replication begins. May be single (prokaryotes) or multiple (eukaryotes)
Introns
origin of replication
Going APE
mRNA stop codons
10. Hydroxy proline and hydroxylysine
Guanine has a
Double Strand DNA repair
promoter
Hydroxylation of which amino acids are attached to Glycine to form collagen
11. 9+2 arrangement of microtubules -
transversion
Cell cycle
Excocytosis of collagen
Cilia structure
12. Immotile cilia due to a dyenin arm defect. Results in male nad female inferticility (sperm immotile) - bronchiectasis - and recurrent sinusisits - associated with situs inversus
Higher the cholesterol or long saturated fatty acid content
dyenin
Kartageners syndrome
tRNA Structure
13. Must be both activated and inactivated for cell cycle to progress
DNA topoisomerases
Free ribosomes
histone octamer names
Cyclin - CDK
14. Different exons can be combined to make nique protiens in different times
What type of collagen is most affected in Ehlers Danlos
Elastin
Functional organization of the gene
Alternate splicing
15. Create a nick in the helix to relieve supercoils created during replication
Kartageners syndrome
DNA topoisomerases
Protein synthesis is in which direction
Protein synthesis initiation
16. Regulatory proteins that control cell cycle events; phase specific; activated CDKs
Deamination of cytosine makes
Hereditary non polyposis colorectal cancer
dyenin
Cyclins
17. Inhibits bacterials dihydrofolate reducatese down thymine
helicase
Free ribosomes
DNA pol III
trimethoprim
18. 1 RNA polymerase (multisubunite complex) makes all 3 kinds of RNA
pyrimadines
Digoxin (cardiac glycosides)
Cilia structure
Prokaryote RNA pol
19. Ribonucleotide reductase
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
Aminoglycosides
Total energy expenditure requirement for translocation
microtubule
20. Greater melting temperature lower fluidity
Higher the cholesterol or long saturated fatty acid content
Silencer
Where do introns and exons stay
Stable (quiescent)
21. UGA - UAG - UAA
mRNA stop codons
transition
Cholchicine
pyrimadines
22. Inhibits dihydrofolate reductase down thymine
Base excision repair
Methotrexate
Elongation
Sodium K ATPase
23. Attachment of ubiquitin to defective proteinds to tag them for breakdown
Loading tRNA on to ribosome energy requirement
Methotrexate
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
Proteosomal degradation
24. Unattached to any membrane; site of cytosolic and organeller prtoeins
Aminoglycosides
alpha amintin
Free ribosomes
Rough ER
25. P53 and RB normally inhibit g1 to S progression
nucleosid
Tumor Suppressors
Guanine has a
Loading tRNA on to ribosome energy requirement
26. Same aa often base change in 3rd position of codon
Replication fork
Stable (quiescent)
silent mutation
Free ribosomes
27. Codes for formyl methionine (f - Met)
Enhancers and silencer may be located_____
Free ribosomes
Steps in splicing
AUG codes For what in prokaryotes
28. Capping on 5 prime end (7 methylguanosine) -
Step one of RNA processing
Tetracyclines
universal
Cell cycle order
29. Promoter - enhancer - promoter - TATA- transcription initiation site - coding region (including exons and introns) and then the AATAAA
Chediak Higashi syndrome
Single Strand DNA Repair types
Functional organization of the gene
Cyclins
30. MRNA
Xeroderma pigmentosum
Mismatch repair
capped and tail transcript is called
nucleotide
31. VItamin C
Prokaryote RNA pol
purines
What does the hydroxylation of proline and lysine require
Xeroderma pigmentosum
32. Microtubule polymerization defect resulting in lowered phagocytosis. results in recurrent pyogenic infections - partial albinism and peripheral neuropathy
Chediak Higashi syndrome
hydroxyurea
DNA ligase
Euchromatin
33. Substituting a pyramidine for a pyrimadine
C- G bond
transition
Collagen
histone octamer names
34. Prokaryotic only. Elongates leading strand by adding deoxynucleotides to the 3prime end. Elongates laggin strand. 3 prime to 5 prime exonuclease activity
DNA pol III
Total energy expenditure requirement for translocation
Aminoacylt - tRNA synthetase
actin and myosin
35. Methionine - which may be removed before translation is completed
In eukaryotes the starting amino acid is...
Guanine has a
Common amino acids in elastin
transversion
36. Each codon specifies only 1 amino acid
unambiguous
Eukaroytes
What ties teh nucleosome together
Chloramphenicol
37. Anti cancer - act on microtubules
Pyrimidines
Vincristine/Vinblastine
Chediak Higashi syndrome
Covalent alterations
38. Non homologous end joining
Permanent cells
Aminoacylt - tRNA synthetase
Hydroxylation of which amino acids are attached to Glycine to form collagen
Double Strand DNA repair
39. Prevents stranges from reannealing
Tetracyclines
Griseofulvin
single stranded binding proteinds
Purines
40. A malfunction of mismatch repair (MUt L etc..)
Vincristine/Vinblastine
C- G bond
Hereditary non polyposis colorectal cancer
Immunohistochemical stains vimentin
41. One codon AUG
mRNA is syntehsized in which direction?
methionine is only encoded by
Order of mitosis
dyenin
42. Site of secretory protiens (mucus secreting goblet cells and antibody secreting cells)
Which end of the tRNA is the amino acid bound to?
Rough ER
Pyrimidines
Introns
43. Seals
DNA ligase
Kartageners syndrome
Elongation
Elastin
44. Cylindrical structure composed of helical array of plymerized dimers of alpha and beta tubulin - flagella - cilia - mitotic spindle - grows slowly collapses quickly
microtubule
polyadenylation does/does not require a template
Osteogenesis Imperfecta
Hereditary non polyposis colorectal cancer
45. ATP- AMP (2 phosphoanhydride bonds)
capped and tail transcript is called
tRNA aminoacylation
helicase
Fluoroquinolones
46. Poly adenylation
6MP
step two of RNA processing
Collagedn synthesis where?
chromatin structure
47. Change resulting in misreading of all nucleotides downstream - usually resulting in a truncated non functional protien
mRNA is syntehsized in which direction?
frame shift
Kartageners syndrome
Smooth ER
48. Asymmetric fluid bilayer - contains - cholesterol - phospholipids - sphingoplipids - glycolipids - and protiends
purines
Plasma membrane composition
Tetracyclines
Loading tRNA on to ribosome energy requirement
49. Condensed - transciptionally inactive HC- Highly condensed
Clindamycin
Example of permanent cells
Termination
Heterochromatin
50. Accurate base pairing is required only in the first 2 nucleotide positions of an mRNA so codons differing ht e3rd wobble psoition may code for the same tRNA/amino acid code
tRNA
step two of RNA processing
Hydroxylation of which amino acids are attached to Glycine to form collagen
methionine is only encoded by