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First Aid: Biochemistry Molecular

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Microtubule polymerization defect resulting in lowered phagocytosis. results in recurrent pyogenic infections - partial albinism and peripheral neuropathy






2. Site where RNA polymerase and multiple other transciption factors bind to DNA upstream from gene locus (AT rich upstream sequence with TATA and CAAT boxes)






3. (A - G) 2 rings Pure As Gold






4. Negatively charged DNA loops twice around histone octamers create a nucloesome bead.






5. Anti cancer - act on microtubules






6. Ketone






7. Retrograde to microtubules






8. 5 prime to 3 prime






9. Condensed - transciptionally inactive HC- Highly condensed






10. Binds 50S blocking translocation






11. Base+ribose+phosphate linked by a phosphodiester bond






12. More than 1 codon may code for the same amino acid






13. In the nucleus after transcitpion and only processed RNA is transporte out of the nucleus






14. Specific glycosylases recognize and remove damaged bases - AP endonuclease cuts DNA at pyrimidne site - empty sugar is removed and the gap is filled and resealed






15. Brings together 2 ends of DNA fragments no requirement for homology






16. Muscle






17. Change resulting in early stop codon






18. The N to C






19. Commonly results in dramatic decrease in amount of gene transcribed






20. Cleave terminal regions of procollagen to transform into insoluable tropocolagen






21. Inhibits 50S peptidyl transferase






22. Elastase






23. Ribonucleotide reductase






24. Different exons can be combined to make nique protiens in different times






25. Inhibit DNA gyrase (specific prokaryotic topoisomerase)






26. 1 RNA polymerase (multisubunite complex) makes all 3 kinds of RNA






27. Prokaryotic only. Degrades RNA primer and fills in the gap with DNA (5 prime to 3 prime exonuclease)






28. Splicing out of introns






29. Faulty collagen synthesis causing 1) hyperextensible skin 2) tendency to bleed 3) hypermobile joints






30. Genetic code is conserved throughout evolution






31. Completed protein is released from ribosme through simple hydrolosis and dissociates






32. Codes for formyl methionine (f - Met)






33. Bind 30S subunit preventing attachment of aminoacyl - tRNA






34. Non homologous end joining






35. ATP- AMP (2 phosphoanhydride bonds)






36. Anterograde to microtubule






37. 4 high enrgy bonds






38. Y shaped region along DNA template where leading and lagging strands are syntehsized






39. 1P blocked by chloramphenicaol and macrolide






40. Alpha 1 antitrypisn






41. Three amino acids necessary for purine synthesis= glutamine - aspartate and glycine






42. Unattached to any membrane; site of cytosolic and organeller prtoeins






43. Prevents stranges from reannealing






44. Prokaryotic only. Elongates leading strand by adding deoxynucleotides to the 3prime end. Elongates laggin strand. 3 prime to 5 prime exonuclease activity






45. Does not






46. UGA - UAG - UAA






47. VItamin C






48. Neurons - skeletal - and cardiac muscle - RBCs






49. Introns stay In the nucleus whereas EXons EXit and are EXpressed






50. Exocytose procollagen into extracellylar sace