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First Aid: Biochemistry Molecular

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Faulty collagen synthesis causing 1) hyperextensible skin 2) tendency to bleed 3) hypermobile joints






2. G1 - S - G2 - Mitosis






3. Site where RNA polymerase and multiple other transciption factors bind to DNA upstream from gene locus (AT rich upstream sequence with TATA and CAAT boxes)






4. Cleave terminal regions of procollagen to transform into insoluable tropocolagen






5. Ribonucleotide reductase






6. Antifungal - act on microtubules






7. 4 high enrgy bonds






8. Cylindrical structure composed of helical array of plymerized dimers of alpha and beta tubulin - flagella - cilia - mitotic spindle - grows slowly collapses quickly






9. Y shaped region along DNA template where leading and lagging strands are syntehsized






10. Condensed - transciptionally inactive HC- Highly condensed






11. Prophas - metaphase - anaphase telophase






12. Does not






13. Specific endonucleases release the oligonucleotide containing damaged bases. DNA polymerase and logase fill and resealt eh gap






14. 1P (blocked by tetracycline)






15. Create a nick in the helix to relieve supercoils created during replication






16. DNA And RNA synthesized in the 5-3 direction






17. One codon AUG






18. Capping on 5 prime end (7 methylguanosine) -






19. Base + ribose






20. Mutation in nucleotide excision repair Dry skin with melanoma and other cancers






21. Anti breast cancer - acts on mts






22. Inhibit DNA gyrase (specific prokaryotic topoisomerase)






23. Asymmetric fluid bilayer - contains - cholesterol - phospholipids - sphingoplipids - glycolipids - and protiends






24. Base+ribose+phosphate linked by a phosphodiester bond






25. Prevents stranges from reannealing






26. AUG inAUGurates protein synthesis






27. Tansport cellular cargo toward opposite ends of microtubule tracks






28. Particular sequnece in genomre where DNA replication begins. May be single (prokaryotes) or multiple (eukaryotes)






29. Type III






30. UGA - UAG - UAA






31. Commonly results in dramatic decrease in amount of gene transcribed






32. Same aa often base change in 3rd position of codon






33. Ketone






34. 75-90 nucleotides - 2ary structure cloverleaf form anticodon end is opposite 3 prime aminoacyl end






35. Codes for formyl methionine (f - Met)






36. Connective tissue






37. Regulatory proteins that control cell cycle events; phase specific; activated CDKs






38. Genetic bone disorder (brittle bone disease) type 1 colalgen - fractures (during birth) 2) Blue sclerae 3) hearing loss 4) dental imperfections 1:10000 may be confused with child abuse






39. Made from orogate precuror with PRPP added later






40. Microtubule polymerization defect resulting in lowered phagocytosis. results in recurrent pyogenic infections - partial albinism and peripheral neuropathy






41. Activated by GTP hydrolosis initiation factors help assembel the 40 S ribosomal subunites with the initiatior tRNA and are released whent he mRNA and the ribosomal subunit assemple with the complex






42. Phosphorylation - glycosloation - hyderoxylation






43. Change resulting in early stop codon






44. Has enough energy to created the peptide bond






45. Checkpoints control transition between phases of cell cycle. regulated by cyclins - CDKs and tumor suppressors. Mitosis (shortest phse)






46. Neurons - skeletal - and cardiac muscle - RBCs






47. Remain in G0 regenerate from stem cells






48. HS1 - HSB - H2 - H4






49. Neuroglia






50. Trimming removal of n or c terminal propeptides from zymogens to generate mature proteinds