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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Prokaryotic only. Degrades RNA primer and fills in the gap with DNA (5 prime to 3 prime exonuclease)
Labile
Higher the cholesterol or long saturated fatty acid content
Associations of Ehlers Danlos
DNA pol I
2. H1 string
What ties teh nucleosome together
tRNA Structure
Exons
histone octamer names
3. Base + ribose
DNA topoisomerases
silent mutation
origin of replication
nucleosid
4. Stretch of DNA that alters gene expression by binding transcription factors
actin and myosin
Enhancer
Neurofilaments
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
5. Close to - far from or even within (in an intron) the gene whose expression it regulates
Enhancers and silencer may be located_____
Purines
degenerate or redundant
Mismatch repair
6. Prophas - metaphase - anaphase telophase
Methotrexate
Order of mitosis
DNA pol III
Paclitaxil
7. Makes an RNA primer on which DNA polymerase II can initiate replication
Where do introns and exons stay
Loading tRNA on to ribosome energy requirement
Primase
unambiguous
8. Even 40S 60S =80S
Eukaroytes
Associations of Ehlers Danlos
Purines
Cilia structure
9. 1P blocked by chloramphenicaol and macrolide
Translocation
Associations of Ehlers Danlos
Griseofulvin
Free ribosomes
10. ATP- AMP (2 phosphoanhydride bonds)
tRNA aminoacylation
Covalent alterations
Initial transcript without processing is known as
Outside the cell what processing must be done in procolalgen
11. RER translation of collagen alpha chains (preprocollagen) usually Gly-X-Y
Xeroderma pigmentosum
nucleotide
Collagedn synthesis where?
6MP
12. Xlinked recessive IV collagen bm - kidney - ear and eye -- nephritis and defness ocular disturbances
Guanine has a
pyrimadines
silent mutation
Alports syndrome
13. Intervening noncoding segments of DNA
What ties teh nucleosome together
Introns
Glycosolation
Alternate splicing
14. Capping on 5 prime end (7 methylguanosine) -
Step one of RNA processing
C- G bond
alpha amintin
RNA processing in eukaryotes occurs
15. Non homologous end joining
Double Strand DNA repair
Euchromatin
Which end of the nucleotide has the triphosphate
Order of mitosis
16. Inhibit DNA gyrase (specific prokaryotic topoisomerase)
Fluoroquinolones
Step one of RNA processing
Protein synthesis initiation
The only histone not on the core
17. Inhibits thymidylate synthase down thymine
Vincristine/Vinblastine
Going APE
alpha amintin
5FU
18. More than 1 codon may code for the same amino acid
trimethoprim
DNA topoisomerases
degenerate or redundant
origin of replication
19. Antifungal - act on microtubules
Covalent alterations
Griseofulvin
What ties teh nucleosome together
universal
20. DNA And RNA synthesized in the 5-3 direction
Paclitaxil
Macrolides
unambiguous
DNA/RNA/Protein syntesis direction
21. Inhibits the atpase which increases intracellular sodium which increases intracellular calcium increases cardiaccontractility
Digoxin (cardiac glycosides)
Which end of a growing DNA strand is the target
silent mutation
Glycosolation
22. Genetic code is conserved throughout evolution
mRNA start codons
universal
Eukaroytes
trimethoprim
23. Retrograde to microtubules
Tropocollagen cross links between_____ to form____
dyenin
cytokeratin
Common amino acids in elastin
24. (A - G) 2 rings Pure As Gold
Termination
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
Purines
Post - translational modifications
25. Faulty collagen synthesis causing 1) hyperextensible skin 2) tendency to bleed 3) hypermobile joints
Ehlers Danlos
Purines
the tRNA- amino acid bond
AUG codes For what in prokaryotes
26. Lysine/hydroxylysine and combines to form collagen
origin of replication
histone octamer names
Which end of a growing DNA strand is the target
Tropocollagen cross links between_____ to form____
27. 1) primary transcript combines with snRNPs and other proteins to form spliceosome 2) lariat shaped intermediate is generated 3) Lariat is removed and released to precisely join 2 exons
Which end of the tRNA is the amino acid bound to?
Cilia structure
Steps in splicing
Chediak Higashi syndrome
28. Methyl THYmine has a meTHYl
Excocytosis of collagen
Translocation
Oubain
Thymine has a
29. Anti breast cancer - acts on mts
Plasma membrane composition
Paclitaxil
Tetracyclines
What type of collagen is most affected in Ehlers Danlos
30. AD and AR- associated iwth joint dislocation - berry aneurysms - organ rupture
Order of mitosis
universal
Where do introns and exons stay
Associations of Ehlers Danlos
31. Site of secretory protiens (mucus secreting goblet cells and antibody secreting cells)
Digoxin (cardiac glycosides)
Elongation
Nucleotide excision repair
Rough ER
32. Cleave terminal regions of procollagen to transform into insoluable tropocolagen
Paclitaxil
Outside the cell what processing must be done in procolalgen
Plasma membrane composition
frame shift
33. 1 RNA polymerase (multisubunite complex) makes all 3 kinds of RNA
actin and myosin
Prokaryote RNA pol
hydroxyurea
Translocation
34. 9+2 arrangement of microtubules -
Cyclins
Mebendazole/thiabendazole
Functional organization of the gene
Cilia structure
35. Connective tissue
Immunohistochemical stains vimentin
Elastin
Enhancer
Osteogenesis Imperfecta
36. G1 - S - G2 - Mitosis
Ehlers Danlos
Cell cycle order
Promoter mutation
White codon is at the 3 prime end of a tRNA
37. Anterograde to microtubule
Griseofulvin
missense mutation
kinesin
Step one of RNA processing
38. Does not
Enhancer
polyadenylation does/does not require a template
Labile
alpha amintin
39. Rampant - Massive - TIny rRNA is most common - then mRNA and then tRNA
Total energy expenditure requirement for translocation
Which is the most and least abundant type of RNA
Excocytosis of collagen
Mebendazole/thiabendazole
40. Muscle
Fluoroquinolones
desmin
frame shift
Ehlers Danlos
41. Regulatory proteins that control cell cycle events; phase specific; activated CDKs
Silencer
Digoxin (cardiac glycosides)
Cyclins
Non homologous end joining
42. Microvilli - muscle contraction - cytokinesis - adhering juntions
Step one of RNA processing
actin and myosin
Elastin
5FU
43. Y shaped region along DNA template where leading and lagging strands are syntehsized
dyenin
hydroxyurea
Tropocollagen cross links between_____ to form____
Replication fork
44. VItamin C
What does the hydroxylation of proline and lysine require
Double Strand DNA repair
Aminoglycosides
Introns
45. No proofreading function but can initiate chains. RNA poymerase II opens DNA at promoter site
Cell cycle order
promoter
desmin
Proofreading function in eukaryotic RNA
46. Change resulting in misreading of all nucleotides downstream - usually resulting in a truncated non functional protien
Non homologous end joining
AUG codes For what in prokaryotes
Vincristine/Vinblastine
frame shift
47. Neurons
Neurofilaments
Xeroderma pigmentosum
the tRNA- amino acid bond
Purines
48. Neurons - skeletal - and cardiac muscle - RBCs
frame shift
Oubain
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
Example of permanent cells
49. 2 H bonds greater GC content greater melting point
A- T
Elastin
the tRNA- amino acid bond
Digoxin (cardiac glycosides)
50. H1
intermediate filaments
Elastase is inhibited by
Elongation
The only histone not on the core