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First Aid: Biochemistry Molecular

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Close to - far from or even within (in an intron) the gene whose expression it regulates






2. MRNA






3. Particular sequnece in genomre where DNA replication begins. May be single (prokaryotes) or multiple (eukaryotes)






4. Site where RNA polymerase and multiple other transciption factors bind to DNA upstream from gene locus (AT rich upstream sequence with TATA and CAAT boxes)






5. DNA And RNA synthesized in the 5-3 direction






6. Binds 50S blocking translocation






7. 5 prime to 3 prime






8. Faulty collagen synthesis causing 1) hyperextensible skin 2) tendency to bleed 3) hypermobile joints






9. Same aa often base change in 3rd position of codon






10. Substituting a pyramidine for a pyrimadine






11. Base+ribose+phosphate linked by a phosphodiester bond






12. Elastase






13. Brings together 2 ends of DNA fragments no requirement for homology






14. Inhibits ribonucleotide reductase






15. The 3 prime hydroxyl of the nascent chain is the target






16. CCA AT 3 PRIME END






17. Splicing out of introns






18. Seals






19. Bind 50S blocking translocation






20. Anti cancer - act on microtubules






21. Checkpoints control transition between phases of cell cycle. regulated by cyclins - CDKs and tumor suppressors. Mitosis (shortest phse)






22. Commonly results in dramatic decrease in amount of gene transcribed






23. Regulatory proteins that control cell cycle events; phase specific; activated CDKs






24. Prokaryotic only. Degrades RNA primer and fills in the gap with DNA (5 prime to 3 prime exonuclease)






25. Xlinked recessive IV collagen bm - kidney - ear and eye -- nephritis and defness ocular disturbances






26. Even 40S 60S =80S






27. 2 H bonds greater GC content greater melting point






28. Anit helminth - act on microtubules






29. VItamin C






30. Inhibit formation of the initation complex and cause misreading of mRNA






31. Rampant - Massive - TIny rRNA is most common - then mRNA and then tRNA






32. Nucleotide excision repair - Base Excision repair - Mismath repair






33. Neurons






34. Genetic code is conserved throughout evolution






35. Three amino acids necessary for purine synthesis= glutamine - aspartate and glycine






36. Phosphorylation - glycosloation - hyderoxylation






37. Unmethylated - newly synthesized string is recognized - mismatched nucleotides are removed and the gap is filled and resealed






38. Mutation in nucleotide excision repair Dry skin with melanoma and other cancers






39. P53 and RB normally inhibit g1 to S progression






40. Lysine/hydroxylysine and combines to form collagen






41. Enter G1 from G0 when stimulated Hepatocytes/lymphocytes






42. Ribonucleotide reductase






43. Proline - glycine






44. AUG inAUGurates protein synthesis






45. CUT 1 ring Cut the Py






46. Cylindrical structure composed of helical array of plymerized dimers of alpha and beta tubulin - flagella - cilia - mitotic spindle - grows slowly collapses quickly






47. No proofreading function but can initiate chains. RNA poymerase II opens DNA at promoter site






48. Ketone






49. Neurons - skeletal - and cardiac muscle - RBCs






50. Promoter - enhancer - promoter - TATA- transcription initiation site - coding region (including exons and introns) and then the AATAAA