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First Aid: Biochemistry Molecular

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. 4 high enrgy bonds






2. Specific endonucleases release the oligonucleotide containing damaged bases. DNA polymerase and logase fill and resealt eh gap






3. Trimming removal of n or c terminal propeptides from zymogens to generate mature proteinds






4. Cyclin depndent kinases; consituative and inactive






5. CCA AT 3 PRIME END






6. Y shaped region along DNA template where leading and lagging strands are syntehsized






7. Made from IMP precursor






8. Brings together 2 ends of DNA fragments no requirement for homology






9. Exocytose procollagen into extracellylar sace






10. Inhibit DNA gyrase (specific prokaryotic topoisomerase)






11. Phosphorylation - glycosloation - hyderoxylation






12. Commonly results in dramatic decrease in amount of gene transcribed






13. One codon AUG






14. Codes for formyl methionine (f - Met)






15. Three amino acids necessary for purine synthesis= glutamine - aspartate and glycine






16. Neurons






17. Change resulting in misreading of all nucleotides downstream - usually resulting in a truncated non functional protien






18. No proofreading function but can initiate chains. RNA poymerase II opens DNA at promoter site






19. Inhibits dihydrofolate reductase down thymine






20. Genetic code is conserved throughout evolution






21. Substituting a purine for a pyrimdine or vice versa






22. Proline - glycine






23. 2 H bonds greater GC content greater melting point






24. Inhibit formation of the initation complex and cause misreading of mRNA






25. ATP ase that links peripheral 9 doublets and causes bending of cilium by differential sliding of doublets






26. Site where RNA polymerase and multiple other transciption factors bind to DNA upstream from gene locus (AT rich upstream sequence with TATA and CAAT boxes)






27. H1 string






28. Prokaryotic only. Degrades RNA primer and fills in the gap with DNA (5 prime to 3 prime exonuclease)






29. Site of dteroid synthesis and detoxification of druigs and poisons (liver hepatocytes and steroid horomore adrenal cortex)






30. UGA - UAG - UAA






31. Inhibits thymidylate synthase down thymine






32. Completed protein is released from ribosme through simple hydrolosis and dissociates






33. AUG inAUGurates protein synthesis






34. AD and AR- associated iwth joint dislocation - berry aneurysms - organ rupture






35. Inhibits the atpase which increases intracellular sodium which increases intracellular calcium increases cardiaccontractility






36. Attachment of ubiquitin to defective proteinds to tag them for breakdown






37. Microvilli - muscle contraction - cytokinesis - adhering juntions






38. Vimentin - desmin - cytockeratin - glial fibrillary acid proteins - neurofilaments






39. 75-90 nucleotides - 2ary structure cloverleaf form anticodon end is opposite 3 prime aminoacyl end






40. Intervening noncoding segments of DNA






41. Blocks denovo purine synthesis






42. Enter G1 from G0 when stimulated Hepatocytes/lymphocytes






43. Faulty collagen synthesis causing 1) hyperextensible skin 2) tendency to bleed 3) hypermobile joints






44. Hydroxy proline and hydroxylysine






45. Create a nick in the helix to relieve supercoils created during replication






46. CUT 1 ring Cut the Py






47. Capping on 5 prime end (7 methylguanosine) -






48. Never go to Go divide rapidly with short G1 bone marrow - gut epithelium - skin - hair follicles






49. Splicing out of introns






50. 1 RNA polymerase (multisubunite complex) makes all 3 kinds of RNA