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First Aid: Biochemistry Molecular

Instructions:
  • Answer 50 questions in 15 minutes.
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  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. A site - incoming aminoacyl tRNA - Psite accomodates growing Peptide - E site holds EmplytRNA as it exits






2. Bind 50S blocking translocation






3. Lysine/hydroxylysine and combines to form collagen






4. Exocytose procollagen into extracellylar sace






5. Three amino acids necessary for purine synthesis= glutamine - aspartate and glycine






6. Condensed - transciptionally inactive HC- Highly condensed






7. Genetic bone disorder (brittle bone disease) type 1 colalgen - fractures (during birth) 2) Blue sclerae 3) hearing loss 4) dental imperfections 1:10000 may be confused with child abuse






8. Nucleotide excision repair - Base Excision repair - Mismath repair






9. Prokaryotic only. Elongates leading strand by adding deoxynucleotides to the 3prime end. Elongates laggin strand. 3 prime to 5 prime exonuclease activity






10. Anti cancer - act on microtubules






11. Substituting a purine for a pyrimdine or vice versa






12. MRNA






13. Proline - glycine






14. Intervening noncoding segments of DNA






15. Inhibit formation of the initation complex and cause misreading of mRNA






16. Aminoacyl - tRNA binds to A site 2) peptidyltransferase catalyzes peptide bond formation transfers growing polypeptie to amino acid in A site 3) ribosome advances 3 nucleotides toward the 3 prime end of RNA moving peptiydyl RNA to P site






17. Unwinds DNA template at replication fork






18. Unmethylated - newly synthesized string is recognized - mismatched nucleotides are removed and the gap is filled and resealed






19. The 5prime end (energy for the bond)






20. Never go to Go divide rapidly with short G1 bone marrow - gut epithelium - skin - hair follicles






21. P53 and RB normally inhibit g1 to S progression






22. The 3 prime end






23. In the nucleus after transcitpion and only processed RNA is transporte out of the nucleus






24. The 3 prime hydroxyl of the nascent chain is the target






25. Xlinked recessive IV collagen bm - kidney - ear and eye -- nephritis and defness ocular disturbances






26. Methionine - which may be removed before translation is completed






27. 3 sodium out for 2 potassium in (nout - kin)takes 1 atp and the machine is phosphorylated during the machine cycle






28. Y shaped region along DNA template where leading and lagging strands are syntehsized






29. HS1 - HSB - H2 - H4






30. Type III






31. Genetic code is conserved throughout evolution






32. Mutation in nucleotide excision repair Dry skin with melanoma and other cancers






33. Change resulting in early stop codon






34. Changed aaconservative - new aa is similar in chemical structure






35. Attachment of ubiquitin to defective proteinds to tag them for breakdown






36. RNA polymerase I makes rRNA - RNA pol II makes mRNA - RNA pol III makes tRNA






37. Scrutinizes aa before and after it binds to tRNA. If incorrect bond is hydrolyzed.






38. Anti breast cancer - acts on mts






39. Contain the actual genetic information coding for protein






40. Even 40S 60S =80S






41. Tansport cellular cargo toward opposite ends of microtubule tracks






42. Anit helminth - act on microtubules






43. Particular sequnece in genomre where DNA replication begins. May be single (prokaryotes) or multiple (eukaryotes)






44. Inhibits the atpase which increases intracellular sodium which increases intracellular calcium increases cardiaccontractility






45. Ketone






46. Retrograde to microtubules






47. Made from IMP precursor






48. Less condensed - transciptionally active=eu truly transcobed






49. Accurate base pairing is required only in the first 2 nucleotide positions of an mRNA so codons differing ht e3rd wobble psoition may code for the same tRNA/amino acid code






50. Inhibits thymidylate synthase down thymine







Sorry!:) No result found.

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