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First Aid: Biochemistry Molecular

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. P53 and RB normally inhibit g1 to S progression






2. Completed protein is released from ribosme through simple hydrolosis and dissociates






3. RNA polymerase I makes rRNA - RNA pol II makes mRNA - RNA pol III makes tRNA






4. Type III






5. Prevents stranges from reannealing






6. HS1 - HSB - H2 - H4






7. Read froma fixed starting point as a continous sequenecs of bases






8. Poly adenylation






9. The N to C






10. Introns stay In the nucleus whereas EXons EXit and are EXpressed






11. Three amino acids necessary for purine synthesis= glutamine - aspartate and glycine






12. Site of secretory protiens (mucus secreting goblet cells and antibody secreting cells)






13. Bm - kidney - ears and eyes






14. AUG inAUGurates protein synthesis






15. Stretch of DNA that alters gene expression by binding transcription factors






16. Different exons can be combined to make nique protiens in different times






17. Enter G1 from G0 when stimulated Hepatocytes/lymphocytes






18. Retrograde to microtubules






19. 1) primary transcript combines with snRNPs and other proteins to form spliceosome 2) lariat shaped intermediate is generated 3) Lariat is removed and released to precisely join 2 exons






20. Genetic bone disorder (brittle bone disease) type 1 colalgen - fractures (during birth) 2) Blue sclerae 3) hearing loss 4) dental imperfections 1:10000 may be confused with child abuse






21. Prokaryotic only. Degrades RNA primer and fills in the gap with DNA (5 prime to 3 prime exonuclease)






22. Each codon specifies only 1 amino acid






23. Makes an RNA primer on which DNA polymerase II can initiate replication






24. Exocytose procollagen into extracellylar sace






25. Non homologous end joining






26. Particular sequnece in genomre where DNA replication begins. May be single (prokaryotes) or multiple (eukaryotes)






27. Made from orogate precuror with PRPP added later






28. Change resulting in early stop codon






29. Asymmetric fluid bilayer - contains - cholesterol - phospholipids - sphingoplipids - glycolipids - and protiends






30. Bind 30S subunit preventing attachment of aminoacyl - tRNA






31. Muscle






32. The 5prime end (energy for the bond)






33. Remain in G0 regenerate from stem cells






34. No proofreading function but can initiate chains. RNA poymerase II opens DNA at promoter site






35. In the nucleus after transcitpion and only processed RNA is transporte out of the nucleus






36. Must be both activated and inactivated for cell cycle to progress






37. Intervening noncoding segments of DNA






38. Inhibit DNA gyrase (specific prokaryotic topoisomerase)






39. 75-90 nucleotides - 2ary structure cloverleaf form anticodon end is opposite 3 prime aminoacyl end






40. Inhibit formation of the initation complex and cause misreading of mRNA






41. Trimming removal of n or c terminal propeptides from zymogens to generate mature proteinds






42. Has enough energy to created the peptide bond






43. Rampant - Massive - TIny rRNA is most common - then mRNA and then tRNA






44. A site - incoming aminoacyl tRNA - Psite accomodates growing Peptide - E site holds EmplytRNA as it exits






45. Anit helminth - act on microtubules






46. More than 1 codon may code for the same amino acid






47. 3 sodium out for 2 potassium in (nout - kin)takes 1 atp and the machine is phosphorylated during the machine cycle






48. Odd 30S plus 50 S=70S






49. Splicing out of introns






50. Specific endonucleases release the oligonucleotide containing damaged bases. DNA polymerase and logase fill and resealt eh gap