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First Aid: Biochemistry Molecular

Subjects : health-sciences, first-aid

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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1. Unattached to any membrane; site of cytosolic and organeller prtoeins
Enhancers and silencer may be located_____
Macrolides
Free ribosomes
Higher the cholesterol or long saturated fatty acid content

2. Different exons can be combined to make nique protiens in different times
Cilia structure
dyenin
alpha amintin
Alternate splicing

3. Methionine - which may be removed before translation is completed
Replication fork
Cilia structure
In eukaryotes the starting amino acid is...
desmin

4. 4 high enrgy bonds
GFAP
Total energy expenditure requirement for translocation
Hydroxylation of which amino acids are attached to Glycine to form collagen
A- T

5. Rampant - Massive - TIny rRNA is most common - then mRNA and then tRNA
Outside the cell what processing must be done in procolalgen
purines
Elastin
Which is the most and least abundant type of RNA

6. Less condensed - transciptionally active=eu truly transcobed
Going APE
Euchromatin
Order of mitosis
Axonemal dyenin

7. Substituting a pyramidine for a pyrimadine
Silencer
transition
Aminoglycosides
Macrolides

8. Condensed - transciptionally inactive HC- Highly condensed
Heterochromatin
Enhancers and silencer may be located_____
capped and tail transcript is called
Primase

9. UGA - UAG - UAA
single stranded binding proteinds
mRNA stop codons
DNA topoisomerases
pyrimadines

10. Three amino acids necessary for purine synthesis= glutamine - aspartate and glycine
mRNA start codons
Where do introns and exons stay
Gag on pure gold
Collagedn synthesis where?

11. Trimming removal of n or c terminal propeptides from zymogens to generate mature proteinds
actin and myosin
Initial transcript without processing is known as
Proteosomal degradation
Post - translational modifications

12. Inhibits the atpase which increases intracellular sodium which increases intracellular calcium increases cardiaccontractility
Digoxin (cardiac glycosides)
Common amino acids in elastin
Aminoacylt - tRNA synthetase
Free ribosomes

13. Anterograde to microtubule
Sodium K ATPase
universal
Base excision repair
kinesin

14. Seals
DNA ligase
Going APE
mRNA stop codons
cytokeratin

15. Negatively charged DNA loops twice around histone octamers create a nucloesome bead.
hydroxyurea
histone octamer names
chromatin structure
Example of permanent cells

16. Made from IMP precursor
purines
Xeroderma pigmentosum
promoter
Single Strand DNA Repair types

17. In the nucleus after transcitpion and only processed RNA is transporte out of the nucleus
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
tRNA aminoacylation
RNA processing in eukaryotes occurs
methionine is only encoded by

18. Inhibits dihydrofolate reductase down thymine
Where do introns and exons stay
Xeroderma pigmentosum
nucleotide
Methotrexate

19. Inhibits 50S peptidyl transferase
RNA processing in eukaryotes occurs
Labile
unambiguous
Chloramphenicol

20. Connective tissue
Order of mitosis
Immunohistochemical stains vimentin
histone octamer names
GFAP

21. Stretch of DNA that alters gene expression by binding transcription factors
DNA/RNA/Protein syntesis direction
Example of permanent cells
Cyclins
Enhancer

22. Unwinds DNA template at replication fork
unambiguous
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
helicase
Free ribosomes

23. RNA polymerase I makes rRNA - RNA pol II makes mRNA - RNA pol III makes tRNA
AUG codes For what in prokaryotes
Excocytosis of collagen
capped and tail transcript is called
RNA polymerases in eukaryotes

24. Enter G1 from G0 when stimulated Hepatocytes/lymphocytes
nucleosid
Stable (quiescent)
Immunohistochemical stains vimentin
Heterochromatin

25. DNA And RNA synthesized in the 5-3 direction
Mebendazole/thiabendazole
Vincristine/Vinblastine
DNA/RNA/Protein syntesis direction
Enhancer

26. Neuroglia
transition
Tumor Suppressors
GFAP
Axonemal dyenin

27. Specific endonucleases release the oligonucleotide containing damaged bases. DNA polymerase and logase fill and resealt eh gap
methionine is only encoded by
Aminoacylt - tRNA synthetase
Nucleotide excision repair
6MP

28. Commonly results in dramatic decrease in amount of gene transcribed
Macrolides
Promoter mutation
The only histone not on the core
Pyrimidines

29. VItamin C
transversion
DNA topoisomerases
pyrimadines
What does the hydroxylation of proline and lysine require

30. The N to C
mRNA start codons
Protein synthesis is in which direction
Which end of a growing DNA strand is the target
universal

31. Bind 30S subunit preventing attachment of aminoacyl - tRNA
CDKs
Tetracyclines
Deamination of cytosine makes
Pyrimidines

32. Even 40S 60S =80S
Eukaroytes
DNA pol I
Elongation
mRNA start codons

33. Particular sequnece in genomre where DNA replication begins. May be single (prokaryotes) or multiple (eukaryotes)
Aminoacylt - tRNA synthetase
nonsense
Functional organization of the gene
origin of replication

34. Immotile cilia due to a dyenin arm defect. Results in male nad female inferticility (sperm immotile) - bronchiectasis - and recurrent sinusisits - associated with situs inversus
missense mutation
Base excision repair
Kartageners syndrome
Aminoacylt - tRNA synthetase

35. Tansport cellular cargo toward opposite ends of microtubule tracks
Vincristine/Vinblastine
Molecular motor protiesn
Axonemal dyenin
Cilia structure

36. Hn RNA
Cell cycle
6MP
Initial transcript without processing is known as
Protein synthesis is in which direction

37. Substituting a purine for a pyrimdine or vice versa
transversion
frame shift
Glycosolation
Elastin is broken down by

38. The 3 prime end
Tetracyclines
Fluoroquinolones
Which end of the tRNA is the amino acid bound to?
In eukaryotes the starting amino acid is...

39. Cilia - glagella - mitotic spindle - neurons - centrioles
Example of permanent cells
microtubule
Aminoglycosides
capped and tail transcript is called

40. Mutation in nucleotide excision repair Dry skin with melanoma and other cancers
Associations of Ehlers Danlos
Post - translational modifications
DNA ligase
Xeroderma pigmentosum

41. Unmethylated - newly synthesized string is recognized - mismatched nucleotides are removed and the gap is filled and resealed
commaless - non - overlapping
Translocation
Mismatch repair
Proteosomal degradation

42. Phosphorylation - glycosloation - hyderoxylation
Eukaroytes
GFAP
Covalent alterations
Rough ER

43. Inhibits ribonucleotide reductase
Translocation
hydroxyurea
origin of replication
actin and myosin

44. Codes for formyl methionine (f - Met)
Gag on pure gold
Enhancer
AUG codes For what in prokaryotes
Example of permanent cells

45. Site of secretory protiens (mucus secreting goblet cells and antibody secreting cells)
Molecular motor protiesn
Rough ER
capped and tail transcript is called
In eukaryotes the starting amino acid is...

46. Inhibits thymidylate synthase down thymine
DNA/RNA/Protein syntesis direction
Associations of Ehlers Danlos
5FU
Chloramphenicol

47. MRNA
capped and tail transcript is called
Non homologous end joining
histone octamer names
Cell cycle

48. Cleave terminal regions of procollagen to transform into insoluable tropocolagen
Gag on pure gold
trimethoprim
Outside the cell what processing must be done in procolalgen
Elastin is broken down by

49. 5 prime to 3 prime
Steps in splicing
DNA pol I
mRNA is syntehsized in which direction?
hydroxyurea

50. Uracil
Deamination of cytosine makes
Promoter mutation
Tropocollagen cross links between_____ to form____
cytokeratin

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First Aid: Biochemistry Molecular

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