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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Be So Totatally Cool Read Books (bOne - CarTWOlage - Threeticular - Type IV under the floor)
Collagen
DNA pol III
alpha amintin
Protein synthesis is in which direction
2. Antigout - acts on mts
Cholchicine
Smooth ER
Introns
Base excision repair
3. Inhibits dihydrofolate reductase down thymine
A- T
Methotrexate
Which end of the nucleotide has the triphosphate
Clindamycin
4. Activated by GTP hydrolosis initiation factors help assembel the 40 S ribosomal subunites with the initiatior tRNA and are released whent he mRNA and the ribosomal subunit assemple with the complex
pyrimadines
Aminoglycosides
AUG codes For what in prokaryotes
Protein synthesis initiation
5. Splicing out of introns
Step Three of RNA processing
Labile
commaless - non - overlapping
White codon is at the 3 prime end of a tRNA
6. Muscle
Outside the cell what processing must be done in procolalgen
desmin
DNA pol I
Proteosomal degradation
7. AD and AR- associated iwth joint dislocation - berry aneurysms - organ rupture
Which end of a growing DNA strand is the target
DNA pol III
Going APE
Associations of Ehlers Danlos
8. Close to - far from or even within (in an intron) the gene whose expression it regulates
Enhancers and silencer may be located_____
Methotrexate
Replication fork
Axonemal dyenin
9. Commonly results in dramatic decrease in amount of gene transcribed
Example of permanent cells
Promoter mutation
Collagen
Exons
10. H1
Single Strand DNA Repair types
Outside the cell what processing must be done in procolalgen
RNA polymerases in eukaryotes
The only histone not on the core
11. Prokaryotic only. Elongates leading strand by adding deoxynucleotides to the 3prime end. Elongates laggin strand. 3 prime to 5 prime exonuclease activity
Chediak Higashi syndrome
C- G bond
DNA pol III
desmin
12. Regulatory proteins that control cell cycle events; phase specific; activated CDKs
Cyclins
Cell cycle
intermediate filaments
missense mutation
13. Retrograde to microtubules
dyenin
missense mutation
degenerate or redundant
Kartageners syndrome
14. Microtubule polymerization defect resulting in lowered phagocytosis. results in recurrent pyogenic infections - partial albinism and peripheral neuropathy
Functional organization of the gene
cytokeratin
Chediak Higashi syndrome
tRNA activation
15. Anti breast cancer - acts on mts
the tRNA- amino acid bond
Paclitaxil
Oubain
Prokaryotes
16. Hydroxy proline and hydroxylysine
Replication fork
Aminoacylt - tRNA synthetase
Hydroxylation of which amino acids are attached to Glycine to form collagen
Outside the cell what processing must be done in procolalgen
17. Genetic code is conserved throughout evolution
Elastase is inhibited by
universal
tRNA gripping and going places
Collagen
18. Each codon specifies only 1 amino acid
DNA pol III
unambiguous
kinesin
Going APE
19. The 3 prime hydroxyl of the nascent chain is the target
The only histone not on the core
What ties teh nucleosome together
Which end of a growing DNA strand is the target
Macrolides
20. Exocytose procollagen into extracellylar sace
CDKs
Mismatch repair
tRNA gripping and going places
Excocytosis of collagen
21. Anti cancer - act on microtubules
Vincristine/Vinblastine
Paclitaxil
tRNA aminoacylation
Sodium K ATPase
22. GTP
tRNA gripping and going places
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
DNA ligase
RNA polymerases in eukaryotes
23. 5 prime to 3 prime
Primase
Base excision repair
Osteogenesis Imperfecta
mRNA is syntehsized in which direction?
24. Poly adenylation
Proteosomal degradation
step two of RNA processing
Thymine has a
What type of collagen is most affected in Ehlers Danlos
25. Cyclin depndent kinases; consituative and inactive
nucleosid
purines
CDKs
Thymine has a
26. Genetic bone disorder (brittle bone disease) type 1 colalgen - fractures (during birth) 2) Blue sclerae 3) hearing loss 4) dental imperfections 1:10000 may be confused with child abuse
Exons
Labile
Osteogenesis Imperfecta
Replication fork
27. Scrutinizes aa before and after it binds to tRNA. If incorrect bond is hydrolyzed.
purines
White codon is at the 3 prime end of a tRNA
DNA pol III
Aminoacylt - tRNA synthetase
28. Rampant - Massive - TIny rRNA is most common - then mRNA and then tRNA
Loading tRNA on to ribosome energy requirement
Which is the most and least abundant type of RNA
Digoxin (cardiac glycosides)
Excocytosis of collagen
29. Inhibits thymidylate synthase down thymine
Protein synthesis is in which direction
5FU
Primase
Gag on pure gold
30. VItamin C
Hereditary non polyposis colorectal cancer
What does the hydroxylation of proline and lysine require
Proofreading function in eukaryotic RNA
Collagedn synthesis where?
31. More than 1 codon may code for the same amino acid
degenerate or redundant
Labile
Cholchicine
Cilia structure
32. Codes for formyl methionine (f - Met)
desmin
AUG codes For what in prokaryotes
DNA ligase
Cell cycle order
33. Less condensed - transciptionally active=eu truly transcobed
Plasma membrane composition
alpha amintin
Euchromatin
5FU
34. Aminoacyl - tRNA binds to A site 2) peptidyltransferase catalyzes peptide bond formation transfers growing polypeptie to amino acid in A site 3) ribosome advances 3 nucleotides toward the 3 prime end of RNA moving peptiydyl RNA to P site
Sodium K ATPase
Xeroderma pigmentosum
Elongation
Guanine has a
35. Same aa often base change in 3rd position of codon
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
degenerate or redundant
silent mutation
Mebendazole/thiabendazole
36. Changed aaconservative - new aa is similar in chemical structure
Cell cycle
missense mutation
Replication fork
dyenin
37. Trimming removal of n or c terminal propeptides from zymogens to generate mature proteinds
DNA topoisomerases
chromatin structure
Rough ER
Post - translational modifications
38. Makes an RNA primer on which DNA polymerase II can initiate replication
tRNA activation
Cyclins
Primase
Chediak Higashi syndrome
39. Brings together 2 ends of DNA fragments no requirement for homology
Hydroxylation of which amino acids are attached to Glycine to form collagen
Immunohistochemical stains vimentin
Sodium K ATPase
Non homologous end joining
40. Bm - kidney - ears and eyes
Primase
Common amino acids in elastin
Type IV collagen is an important structural component of...
Initial transcript without processing is known as
41. Does not
Translocation
Mismatch repair
Free ribosomes
polyadenylation does/does not require a template
42. Capping on 5 prime end (7 methylguanosine) -
tRNA
Step one of RNA processing
tRNA gripping and going places
Stable (quiescent)
43. Inhibits the atpase which increases intracellular sodium which increases intracellular calcium increases cardiaccontractility
Elastase is inhibited by
Non homologous end joining
Digoxin (cardiac glycosides)
Heterochromatin
44. 4 high enrgy bonds
chromatin structure
RNA processing in eukaryotes occurs
Total energy expenditure requirement for translocation
silent mutation
45. Non homologous end joining
helicase
Double Strand DNA repair
Single Strand DNA Repair types
Replication fork
46. (A - G) 2 rings Pure As Gold
Aminoglycosides
Promoter mutation
Purines
Elastin is broken down by
47. No proofreading function but can initiate chains. RNA poymerase II opens DNA at promoter site
mRNA start codons
alpha amintin
nonsense
Proofreading function in eukaryotic RNA
48. A site - incoming aminoacyl tRNA - Psite accomodates growing Peptide - E site holds EmplytRNA as it exits
White codon is at the 3 prime end of a tRNA
commaless - non - overlapping
the tRNA- amino acid bond
Going APE
49. Phosphorylation - glycosloation - hyderoxylation
Prokaryote RNA pol
Step Three of RNA processing
Covalent alterations
Thymine has a
50. Never go to Go divide rapidly with short G1 bone marrow - gut epithelium - skin - hair follicles
DNA topoisomerases
polyadenylation does/does not require a template
Labile
tRNA gripping and going places