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First Aid: Biochemistry Molecular

Instructions:
  • Answer 50 questions in 15 minutes.
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  • Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. CUT 1 ring Cut the Py






2. Tansport cellular cargo toward opposite ends of microtubule tracks






3. Binds 50S blocking translocation






4. Immotile cilia due to a dyenin arm defect. Results in male nad female inferticility (sperm immotile) - bronchiectasis - and recurrent sinusisits - associated with situs inversus






5. Checkpoints control transition between phases of cell cycle. regulated by cyclins - CDKs and tumor suppressors. Mitosis (shortest phse)






6. ATP






7. Rampant - Massive - TIny rRNA is most common - then mRNA and then tRNA






8. Substituting a purine for a pyrimdine or vice versa






9. ATP ase that links peripheral 9 doublets and causes bending of cilium by differential sliding of doublets






10. Anti cancer - act on microtubules






11. 1P blocked by chloramphenicaol and macrolide






12. Inhibit DNA gyrase (specific prokaryotic topoisomerase)






13. Cyclin depndent kinases; consituative and inactive






14. Faulty collagen synthesis causing 1) hyperextensible skin 2) tendency to bleed 3) hypermobile joints






15. The 5prime end (energy for the bond)






16. Enter G1 from G0 when stimulated Hepatocytes/lymphocytes






17. 4 high enrgy bonds






18. Three amino acids necessary for purine synthesis= glutamine - aspartate and glycine






19. Scrutinizes aa before and after it binds to tRNA. If incorrect bond is hydrolyzed.






20. Unattached to any membrane; site of cytosolic and organeller prtoeins






21. Antifungal - act on microtubules






22. 75-90 nucleotides - 2ary structure cloverleaf form anticodon end is opposite 3 prime aminoacyl end






23. Change resulting in early stop codon






24. Regulatory proteins that control cell cycle events; phase specific; activated CDKs






25. Has enough energy to created the peptide bond






26. 3 sodium out for 2 potassium in (nout - kin)takes 1 atp and the machine is phosphorylated during the machine cycle






27. Ketone






28. Hydroxy proline and hydroxylysine






29. Type III






30. Attachment of ubiquitin to defective proteinds to tag them for breakdown






31. Connective tissue






32. Greater melting temperature lower fluidity






33. Stretch of DNA that alters gene expression by binding transcription factors






34. Inhibit formation of the initation complex and cause misreading of mRNA






35. Cleave terminal regions of procollagen to transform into insoluable tropocolagen






36. A site - incoming aminoacyl tRNA - Psite accomodates growing Peptide - E site holds EmplytRNA as it exits






37. UGA - UAG - UAA






38. Nucleotide excision repair - Base Excision repair - Mismath repair






39. 1) primary transcript combines with snRNPs and other proteins to form spliceosome 2) lariat shaped intermediate is generated 3) Lariat is removed and released to precisely join 2 exons






40. Blocks denovo purine synthesis






41. Never go to Go divide rapidly with short G1 bone marrow - gut epithelium - skin - hair follicles






42. Poly adenylation






43. More than 1 codon may code for the same amino acid






44. Each codon specifies only 1 amino acid






45. Be So Totatally Cool Read Books (bOne - CarTWOlage - Threeticular - Type IV under the floor)






46. Uracil






47. Substituting a pyramidine for a pyrimadine






48. Inhibits the atpase which increases intracellular sodium which increases intracellular calcium increases cardiaccontractility






49. Antigout - acts on mts






50. Different exons can be combined to make nique protiens in different times







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