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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Commonly results in dramatic decrease in amount of gene transcribed
Promoter mutation
silent mutation
hydroxyurea
Cholchicine
2. Cilia - glagella - mitotic spindle - neurons - centrioles
transition
Stable (quiescent)
microtubule
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
3. Hn RNA
Initial transcript without processing is known as
DNA pol III
CDKs
Kartageners syndrome
4. Ketone
Aminoglycosides
Replication fork
polyadenylation does/does not require a template
Guanine has a
5. Inhibit formation of the initation complex and cause misreading of mRNA
Higher the cholesterol or long saturated fatty acid content
tRNA gripping and going places
histone octamer names
Aminoglycosides
6. 75-90 nucleotides - 2ary structure cloverleaf form anticodon end is opposite 3 prime aminoacyl end
Heterochromatin
Cell cycle order
tRNA Structure
trimethoprim
7. Stretch of DNA that alters gene expression by binding transcription factors
Example of permanent cells
Non homologous end joining
Enhancer
Xeroderma pigmentosum
8. Unwinds DNA template at replication fork
helicase
actin and myosin
microtubule
chromatin structure
9. Inhibits ribonucleotide reductase
Griseofulvin
White codon is at the 3 prime end of a tRNA
hydroxyurea
Which end of the nucleotide has the triphosphate
10. Anterograde to microtubule
alpha amintin
Kartageners syndrome
Step one of RNA processing
kinesin
11. Less condensed - transciptionally active=eu truly transcobed
Type IV collagen is an important structural component of...
Which end of a growing DNA strand is the target
Euchromatin
Protein synthesis initiation
12. A malfunction of mismatch repair (MUt L etc..)
Smooth ER
Example of permanent cells
Hereditary non polyposis colorectal cancer
universal
13. Methionine - which may be removed before translation is completed
In eukaryotes the starting amino acid is...
microtubule
Euchromatin
nucleotide
14. Methyl THYmine has a meTHYl
DNA pol III
trimethoprim
Thymine has a
DNA pol I
15. 1) primary transcript combines with snRNPs and other proteins to form spliceosome 2) lariat shaped intermediate is generated 3) Lariat is removed and released to precisely join 2 exons
Steps in splicing
Prokaryote RNA pol
Cilia structure
Silencer
16. Strethchy protein within lungs - large artiers - elastic liaments - vocal cords - ligamenta flava)
A- T
Elastin
Functional organization of the gene
5FU
17. Antigout - acts on mts
Prokaryotes
Chloramphenicol
Cholchicine
Griseofulvin
18. Completed protein is released from ribosme through simple hydrolosis and dissociates
Immunohistochemical stains vimentin
Loading tRNA on to ribosome energy requirement
Collagen
Termination
19. Proline - glycine
trimethoprim
Base excision repair
Common amino acids in elastin
tRNA activation
20. Rampant - Massive - TIny rRNA is most common - then mRNA and then tRNA
Which is the most and least abundant type of RNA
Order of mitosis
DNA ligase
Which end of a growing DNA strand is the target
21. Seals
tRNA Structure
DNA ligase
the tRNA- amino acid bond
Initial transcript without processing is known as
22. Different exons can be combined to make nique protiens in different times
Chediak Higashi syndrome
Alternate splicing
Labile
Common amino acids in elastin
23. Xlinked recessive IV collagen bm - kidney - ear and eye -- nephritis and defness ocular disturbances
Macrolides
Cell cycle
Alports syndrome
Eukaroytes
24. Neurons - skeletal - and cardiac muscle - RBCs
Enhancer
AUG codes For what in prokaryotes
Fluoroquinolones
Example of permanent cells
25. Inhibits thymidylate synthase down thymine
5FU
Example of permanent cells
Neurofilaments
Methotrexate
26. Site where negative regulators bind
Silencer
Purines
What type of collagen is most affected in Ehlers Danlos
Step one of RNA processing
27. Same aa often base change in 3rd position of codon
C- G bond
silent mutation
Digoxin (cardiac glycosides)
transversion
28. Retrograde to microtubules
Proofreading function in eukaryotic RNA
dyenin
Hereditary non polyposis colorectal cancer
Tetracyclines
29. Made from IMP precursor
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
DNA pol I
purines
Going APE
30. Bind 50S blocking translocation
Macrolides
Immunohistochemical stains vimentin
What ties teh nucleosome together
Steps in splicing
31. Has enough energy to created the peptide bond
Steps in splicing
AUG codes For what in prokaryotes
Mismatch repair
the tRNA- amino acid bond
32. 4 high enrgy bonds
Ehlers Danlos
Cell cycle
Total energy expenditure requirement for translocation
Termination
33. Accurate base pairing is required only in the first 2 nucleotide positions of an mRNA so codons differing ht e3rd wobble psoition may code for the same tRNA/amino acid code
frame shift
polyadenylation does/does not require a template
Oubain
tRNA
34. Brings together 2 ends of DNA fragments no requirement for homology
Termination
mRNA stop codons
Elastin is broken down by
Non homologous end joining
35. 3 H bonds
C- G bond
Mismatch repair
universal
Elastin
36. You glyucosolate hte pro - alpha chain lysine resudens and form procollagen (triple helix of alpha chains)
unambiguous
Termination
Glycosolation
Protein synthesis initiation
37. Introns stay In the nucleus whereas EXons EXit and are EXpressed
promoter
microtubule
unambiguous
Where do introns and exons stay
38. Binds 50S blocking translocation
Clindamycin
Where do introns and exons stay
histone octamer names
Tetracyclines
39. Anti breast cancer - acts on mts
single stranded binding proteinds
microtubule
Paclitaxil
missense mutation
40. Exocytose procollagen into extracellylar sace
Excocytosis of collagen
Clindamycin
Protein synthesis initiation
AUG codes For what in prokaryotes
41. VItamin C
mRNA start codons
missense mutation
What does the hydroxylation of proline and lysine require
Tropocollagen cross links between_____ to form____
42. Greater melting temperature lower fluidity
Immunohistochemical stains vimentin
Tetracyclines
Higher the cholesterol or long saturated fatty acid content
step two of RNA processing
43. Neuroglia
In eukaryotes the starting amino acid is...
tRNA gripping and going places
GFAP
Cilia structure
44. In the nucleus after transcitpion and only processed RNA is transporte out of the nucleus
RNA processing in eukaryotes occurs
What type of collagen is most affected in Ehlers Danlos
Heterochromatin
Deamination of cytosine makes
45. The N to C
Molecular motor protiesn
Which end of a growing DNA strand is the target
capped and tail transcript is called
Protein synthesis is in which direction
46. Promoter - enhancer - promoter - TATA- transcription initiation site - coding region (including exons and introns) and then the AATAAA
tRNA Structure
Excocytosis of collagen
Functional organization of the gene
promoter
47. Elastase
Elastin is broken down by
Example of permanent cells
step two of RNA processing
Cholchicine
48. Cylindrical structure composed of helical array of plymerized dimers of alpha and beta tubulin - flagella - cilia - mitotic spindle - grows slowly collapses quickly
In eukaryotes the starting amino acid is...
microtubule
Initial transcript without processing is known as
Stable (quiescent)
49. Prokaryotic only. Degrades RNA primer and fills in the gap with DNA (5 prime to 3 prime exonuclease)
tRNA
DNA pol I
Prokaryotes
Step Three of RNA processing
50. Blocks denovo purine synthesis
tRNA gripping and going places
Elastase is inhibited by
6MP
Going APE