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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Substituting a pyramidine for a pyrimadine
transition
helicase
Total energy expenditure requirement for translocation
Mebendazole/thiabendazole
2. Hn RNA
Plasma membrane composition
Elongation
Alternate splicing
Initial transcript without processing is known as
3. H1 string
origin of replication
commaless - non - overlapping
Aminoglycosides
What ties teh nucleosome together
4. 4 high enrgy bonds
Clindamycin
Total energy expenditure requirement for translocation
Gag on pure gold
Initial transcript without processing is known as
5. Scrutinizes aa before and after it binds to tRNA. If incorrect bond is hydrolyzed.
Molecular motor protiesn
Aminoacylt - tRNA synthetase
Cholchicine
Paclitaxil
6. AD and AR- associated iwth joint dislocation - berry aneurysms - organ rupture
tRNA gripping and going places
White codon is at the 3 prime end of a tRNA
Associations of Ehlers Danlos
Common amino acids in elastin
7. Epithelial cells
Macrolides
Higher the cholesterol or long saturated fatty acid content
Labile
cytokeratin
8. AUG inAUGurates protein synthesis
mRNA start codons
Associations of Ehlers Danlos
Neurofilaments
Functional organization of the gene
9. Changed aaconservative - new aa is similar in chemical structure
Termination
missense mutation
Immunohistochemical stains vimentin
helicase
10. Unattached to any membrane; site of cytosolic and organeller prtoeins
methionine is only encoded by
Xeroderma pigmentosum
Free ribosomes
Prokaryotes
11. Elastase
Proofreading function in eukaryotic RNA
Elastin is broken down by
Collagen
DNA pol I
12. Odd 30S plus 50 S=70S
helicase
Where do introns and exons stay
Cell cycle order
Prokaryotes
13. Commonly results in dramatic decrease in amount of gene transcribed
Oubain
tRNA activation
Which is the most and least abundant type of RNA
Promoter mutation
14. Antigout - acts on mts
Cholchicine
GFAP
frame shift
Prokaryote RNA pol
15. Tansport cellular cargo toward opposite ends of microtubule tracks
Type IV collagen is an important structural component of...
Osteogenesis Imperfecta
C- G bond
Molecular motor protiesn
16. More than 1 codon may code for the same amino acid
degenerate or redundant
Step one of RNA processing
Nucleotide excision repair
nucleosid
17. A malfunction of mismatch repair (MUt L etc..)
Covalent alterations
Which is the most and least abundant type of RNA
missense mutation
Hereditary non polyposis colorectal cancer
18. Uracil
Purines
Type IV collagen is an important structural component of...
Deamination of cytosine makes
Proteosomal degradation
19. Inhibit formation of the initation complex and cause misreading of mRNA
Free ribosomes
Vincristine/Vinblastine
Aminoglycosides
Neurofilaments
20. Anti breast cancer - acts on mts
Which is the most and least abundant type of RNA
alpha amintin
Paclitaxil
Cyclin - CDK
21. Accurate base pairing is required only in the first 2 nucleotide positions of an mRNA so codons differing ht e3rd wobble psoition may code for the same tRNA/amino acid code
Stable (quiescent)
Enhancers and silencer may be located_____
Chloramphenicol
tRNA
22. Antifungal - act on microtubules
White codon is at the 3 prime end of a tRNA
tRNA Structure
Cyclin - CDK
Griseofulvin
23. Negatively charged DNA loops twice around histone octamers create a nucloesome bead.
Digoxin (cardiac glycosides)
Common amino acids in elastin
chromatin structure
Mismatch repair
24. Splicing out of introns
Excocytosis of collagen
Step Three of RNA processing
CDKs
Primase
25. Close to - far from or even within (in an intron) the gene whose expression it regulates
helicase
Total energy expenditure requirement for translocation
Enhancers and silencer may be located_____
C- G bond
26. Contain the actual genetic information coding for protein
Exons
Ehlers Danlos
Cyclin - CDK
Prokaryotes
27. Immotile cilia due to a dyenin arm defect. Results in male nad female inferticility (sperm immotile) - bronchiectasis - and recurrent sinusisits - associated with situs inversus
Osteogenesis Imperfecta
Neurofilaments
Kartageners syndrome
Alports syndrome
28. Bind 50S blocking translocation
Macrolides
DNA ligase
Deamination of cytosine makes
Permanent cells
29. Lysine/hydroxylysine and combines to form collagen
Tropocollagen cross links between_____ to form____
Sodium K ATPase
Cholchicine
mRNA is syntehsized in which direction?
30. Specific endonucleases release the oligonucleotide containing damaged bases. DNA polymerase and logase fill and resealt eh gap
Nucleotide excision repair
AUG codes For what in prokaryotes
step two of RNA processing
Axonemal dyenin
31. Retrograde to microtubules
Griseofulvin
Order of mitosis
dyenin
Enhancer
32. Bm - kidney - ears and eyes
Cell cycle
Termination
Type IV collagen is an important structural component of...
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
33. Blocks denovo purine synthesis
alpha amintin
Loading tRNA on to ribosome energy requirement
6MP
Covalent alterations
34. Made from IMP precursor
Ehlers Danlos
RNA processing in eukaryotes occurs
purines
Elastin
35. RNA polymerase I makes rRNA - RNA pol II makes mRNA - RNA pol III makes tRNA
Tetracyclines
single stranded binding proteinds
RNA polymerases in eukaryotes
Free ribosomes
36. Genetic code is conserved throughout evolution
desmin
universal
Which end of a growing DNA strand is the target
White codon is at the 3 prime end of a tRNA
37. GTP
mRNA stop codons
Permanent cells
tRNA gripping and going places
purines
38. 1P blocked by chloramphenicaol and macrolide
trimethoprim
Osteogenesis Imperfecta
Eukaroytes
Translocation
39. Specific glycosylases recognize and remove damaged bases - AP endonuclease cuts DNA at pyrimidne site - empty sugar is removed and the gap is filled and resealed
Base excision repair
Griseofulvin
tRNA Structure
Double Strand DNA repair
40. Methyl THYmine has a meTHYl
Oubain
Thymine has a
Heterochromatin
Base excision repair
41. Greater melting temperature lower fluidity
tRNA gripping and going places
Tetracyclines
Higher the cholesterol or long saturated fatty acid content
pyrimadines
42. Poly adenylation
Which end of the nucleotide has the triphosphate
single stranded binding proteinds
step two of RNA processing
Protein synthesis is in which direction
43. Particular sequnece in genomre where DNA replication begins. May be single (prokaryotes) or multiple (eukaryotes)
origin of replication
Molecular motor protiesn
Proofreading function in eukaryotic RNA
polyadenylation does/does not require a template
44. ATP
Mismatch repair
What ties teh nucleosome together
tRNA activation
Total energy expenditure requirement for translocation
45. 1) primary transcript combines with snRNPs and other proteins to form spliceosome 2) lariat shaped intermediate is generated 3) Lariat is removed and released to precisely join 2 exons
Hereditary non polyposis colorectal cancer
Permanent cells
Outside the cell what processing must be done in procolalgen
Steps in splicing
46. Prokaryotic only. Elongates leading strand by adding deoxynucleotides to the 3prime end. Elongates laggin strand. 3 prime to 5 prime exonuclease activity
DNA pol III
origin of replication
Immunohistochemical stains vimentin
silent mutation
47. Trimming removal of n or c terminal propeptides from zymogens to generate mature proteinds
Post - translational modifications
Osteogenesis Imperfecta
Chediak Higashi syndrome
CDKs
48. CUT 1 ring Cut the Py
silent mutation
Pyrimidines
nucleotide
Axonemal dyenin
49. Y shaped region along DNA template where leading and lagging strands are syntehsized
Replication fork
chromatin structure
Tumor Suppressors
Neurofilaments
50. Bind 30S subunit preventing attachment of aminoacyl - tRNA
Paclitaxil
Tetracyclines
Which end of the nucleotide has the triphosphate
White codon is at the 3 prime end of a tRNA