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First Aid: Biochemistry Molecular

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Mutation in nucleotide excision repair Dry skin with melanoma and other cancers






2. 1P (blocked by tetracycline)






3. Negatively charged DNA loops twice around histone octamers create a nucloesome bead.






4. Commonly results in dramatic decrease in amount of gene transcribed






5. Completed protein is released from ribosme through simple hydrolosis and dissociates






6. ATP- AMP (2 phosphoanhydride bonds)






7. More than 1 codon may code for the same amino acid






8. Elastase






9. Prokaryotic only. Elongates leading strand by adding deoxynucleotides to the 3prime end. Elongates laggin strand. 3 prime to 5 prime exonuclease activity






10. RER translation of collagen alpha chains (preprocollagen) usually Gly-X-Y






11. Cyclin depndent kinases; consituative and inactive






12. Close to - far from or even within (in an intron) the gene whose expression it regulates






13. Particular sequnece in genomre where DNA replication begins. May be single (prokaryotes) or multiple (eukaryotes)






14. No proofreading function but can initiate chains. RNA poymerase II opens DNA at promoter site






15. 3 H bonds






16. 3 sodium out for 2 potassium in (nout - kin)takes 1 atp and the machine is phosphorylated during the machine cycle






17. Regulatory proteins that control cell cycle events; phase specific; activated CDKs






18. Site where RNA polymerase and multiple other transciption factors bind to DNA upstream from gene locus (AT rich upstream sequence with TATA and CAAT boxes)






19. Inhibits the atpase which increases intracellular sodium which increases intracellular calcium increases cardiaccontractility






20. Has enough energy to created the peptide bond






21. The N to C






22. Genetic bone disorder (brittle bone disease) type 1 colalgen - fractures (during birth) 2) Blue sclerae 3) hearing loss 4) dental imperfections 1:10000 may be confused with child abuse






23. You glyucosolate hte pro - alpha chain lysine resudens and form procollagen (triple helix of alpha chains)






24. Neuroglia






25. Epithelial cells






26. Change resulting in misreading of all nucleotides downstream - usually resulting in a truncated non functional protien






27. Site where negative regulators bind






28. Anti breast cancer - acts on mts






29. Methyl THYmine has a meTHYl






30. ATP






31. G1 - S - G2 - Mitosis






32. Ketone






33. Microtubule polymerization defect resulting in lowered phagocytosis. results in recurrent pyogenic infections - partial albinism and peripheral neuropathy






34. AUG inAUGurates protein synthesis






35. Base + ribose






36. Made from orogate precuror with PRPP added later






37. Trimming removal of n or c terminal propeptides from zymogens to generate mature proteinds






38. Substituting a pyramidine for a pyrimadine






39. Capping on 5 prime end (7 methylguanosine) -






40. AD and AR- associated iwth joint dislocation - berry aneurysms - organ rupture






41. Bm - kidney - ears and eyes






42. Read froma fixed starting point as a continous sequenecs of bases






43. Faulty collagen synthesis causing 1) hyperextensible skin 2) tendency to bleed 3) hypermobile joints






44. Vimentin - desmin - cytockeratin - glial fibrillary acid proteins - neurofilaments






45. Each codon specifies only 1 amino acid






46. Unattached to any membrane; site of cytosolic and organeller prtoeins






47. Be So Totatally Cool Read Books (bOne - CarTWOlage - Threeticular - Type IV under the floor)






48. Change resulting in early stop codon






49. Hydroxy proline and hydroxylysine






50. Inhibit DNA gyrase (specific prokaryotic topoisomerase)