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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. No proofreading function but can initiate chains. RNA poymerase II opens DNA at promoter site
Tropocollagen cross links between_____ to form____
Proofreading function in eukaryotic RNA
the tRNA- amino acid bond
White codon is at the 3 prime end of a tRNA
2. The 5prime end (energy for the bond)
histone octamer names
Excocytosis of collagen
Which end of the nucleotide has the triphosphate
Gag on pure gold
3. Bind 30S subunit preventing attachment of aminoacyl - tRNA
Tetracyclines
polyadenylation does/does not require a template
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
Hydroxylation of which amino acids are attached to Glycine to form collagen
4. A site - incoming aminoacyl tRNA - Psite accomodates growing Peptide - E site holds EmplytRNA as it exits
transversion
Outside the cell what processing must be done in procolalgen
Going APE
The only histone not on the core
5. Less condensed - transciptionally active=eu truly transcobed
methionine is only encoded by
transition
missense mutation
Euchromatin
6. Xlinked recessive IV collagen bm - kidney - ear and eye -- nephritis and defness ocular disturbances
tRNA Structure
Elastin
Alports syndrome
White codon is at the 3 prime end of a tRNA
7. Nucleotide excision repair - Base Excision repair - Mismath repair
Single Strand DNA Repair types
Going APE
helicase
Elastin is broken down by
8. Antifungal - act on microtubules
Macrolides
Elastin
Translocation
Griseofulvin
9. Elastase
Step one of RNA processing
Elastin is broken down by
Vincristine/Vinblastine
Neurofilaments
10. Enter G1 from G0 when stimulated Hepatocytes/lymphocytes
GFAP
Alports syndrome
Stable (quiescent)
actin and myosin
11. Type III
Tetracyclines
What type of collagen is most affected in Ehlers Danlos
Molecular motor protiesn
alpha amintin
12. Scrutinizes aa before and after it binds to tRNA. If incorrect bond is hydrolyzed.
nucleotide
Aminoacylt - tRNA synthetase
Kartageners syndrome
silent mutation
13. Greater melting temperature lower fluidity
Cilia structure
Higher the cholesterol or long saturated fatty acid content
Cell cycle order
pyrimadines
14. Must be both activated and inactivated for cell cycle to progress
Cyclin - CDK
microtubule
Exons
Neurofilaments
15. Base + ribose
Euchromatin
Kartageners syndrome
nucleosid
polyadenylation does/does not require a template
16. Bind 50S blocking translocation
Which end of a growing DNA strand is the target
Going APE
Macrolides
Xeroderma pigmentosum
17. Microtubule polymerization defect resulting in lowered phagocytosis. results in recurrent pyogenic infections - partial albinism and peripheral neuropathy
Which end of the tRNA is the amino acid bound to?
Chediak Higashi syndrome
intermediate filaments
Step one of RNA processing
18. 1P blocked by chloramphenicaol and macrolide
nucleotide
origin of replication
Hereditary non polyposis colorectal cancer
Translocation
19. Change resulting in early stop codon
transversion
5FU
nonsense
Exons
20. Inhibit DNA gyrase (specific prokaryotic topoisomerase)
Collagen
Fluoroquinolones
Functional organization of the gene
Total energy expenditure requirement for translocation
21. Binds 50S blocking translocation
Alternate splicing
Eukaroytes
Clindamycin
Higher the cholesterol or long saturated fatty acid content
22. Exocytose procollagen into extracellylar sace
Excocytosis of collagen
Griseofulvin
What ties teh nucleosome together
Total energy expenditure requirement for translocation
23. Substituting a purine for a pyrimdine or vice versa
tRNA aminoacylation
transversion
purines
Aminoacylt - tRNA synthetase
24. You glyucosolate hte pro - alpha chain lysine resudens and form procollagen (triple helix of alpha chains)
Collagedn synthesis where?
Aminoglycosides
Glycosolation
the tRNA- amino acid bond
25. Negatively charged DNA loops twice around histone octamers create a nucloesome bead.
Kartageners syndrome
desmin
Step one of RNA processing
chromatin structure
26. Codes for formyl methionine (f - Met)
AUG codes For what in prokaryotes
Cell cycle
tRNA
Elastin is broken down by
27. Inhibits dihydrofolate reductase down thymine
methionine is only encoded by
C- G bond
What type of collagen is most affected in Ehlers Danlos
Methotrexate
28. Makes an RNA primer on which DNA polymerase II can initiate replication
Protein synthesis is in which direction
Collagedn synthesis where?
Primase
Prokaryote RNA pol
29. VItamin C
What does the hydroxylation of proline and lysine require
pyrimadines
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
Thymine has a
30. Particular sequnece in genomre where DNA replication begins. May be single (prokaryotes) or multiple (eukaryotes)
Alports syndrome
Deamination of cytosine makes
origin of replication
C- G bond
31. Intervening noncoding segments of DNA
Introns
Thymine has a
Hydroxylation of which amino acids are attached to Glycine to form collagen
Termination
32. Bm - kidney - ears and eyes
Neurofilaments
DNA/RNA/Protein syntesis direction
What type of collagen is most affected in Ehlers Danlos
Type IV collagen is an important structural component of...
33. Unattached to any membrane; site of cytosolic and organeller prtoeins
dyenin
Aminoacylt - tRNA synthetase
Free ribosomes
Elongation
34. (A - G) 2 rings Pure As Gold
silent mutation
Aminoacylt - tRNA synthetase
Purines
actin and myosin
35. Capping on 5 prime end (7 methylguanosine) -
Protein synthesis initiation
Stable (quiescent)
Step one of RNA processing
Where do introns and exons stay
36. 1P (blocked by tetracycline)
Chediak Higashi syndrome
Collagedn synthesis where?
Loading tRNA on to ribosome energy requirement
unambiguous
37. Cleave terminal regions of procollagen to transform into insoluable tropocolagen
promoter
helicase
desmin
Outside the cell what processing must be done in procolalgen
38. RER translation of collagen alpha chains (preprocollagen) usually Gly-X-Y
silent mutation
Deamination of cytosine makes
Cell cycle
Collagedn synthesis where?
39. RNA polymerase I makes rRNA - RNA pol II makes mRNA - RNA pol III makes tRNA
Gag on pure gold
What ties teh nucleosome together
RNA polymerases in eukaryotes
Double Strand DNA repair
40. Contain the actual genetic information coding for protein
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
Gag on pure gold
Exons
Base excision repair
41. P53 and RB normally inhibit g1 to S progression
Tumor Suppressors
RNA polymerases in eukaryotes
microtubule
Replication fork
42. Completed protein is released from ribosme through simple hydrolosis and dissociates
Elastin
Functional organization of the gene
Termination
Step one of RNA processing
43. Changed aaconservative - new aa is similar in chemical structure
promoter
Non homologous end joining
missense mutation
Silencer
44. Anit helminth - act on microtubules
dyenin
Collagedn synthesis where?
Cyclin - CDK
Mebendazole/thiabendazole
45. Non homologous end joining
Double Strand DNA repair
Functional organization of the gene
Mismatch repair
mRNA stop codons
46. Muscle
desmin
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
Excocytosis of collagen
silent mutation
47. Anti breast cancer - acts on mts
Steps in splicing
promoter
Paclitaxil
microtubule
48. Unmethylated - newly synthesized string is recognized - mismatched nucleotides are removed and the gap is filled and resealed
Mismatch repair
Outside the cell what processing must be done in procolalgen
DNA ligase
Euchromatin
49. Inhibits thymidylate synthase down thymine
Going APE
AUG codes For what in prokaryotes
actin and myosin
5FU
50. 5 prime to 3 prime
mRNA is syntehsized in which direction?
kinesin
Griseofulvin
Chloramphenicol