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First Aid: Biochemistry Molecular

Subjects : health-sciences, first-aid

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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1. Ketone
Functional organization of the gene
Guanine has a
Silencer
Labile

2. Brings together 2 ends of DNA fragments no requirement for homology
Tumor Suppressors
Non homologous end joining
Methotrexate
Oubain

3. Even 40S 60S =80S
Eukaroytes
tRNA aminoacylation
mRNA is syntehsized in which direction?
alpha amintin

4. 3 H bonds
In eukaryotes the starting amino acid is...
Stable (quiescent)
C- G bond
Exons

5. Inhibits ribonucleotide reductase
Total energy expenditure requirement for translocation
tRNA gripping and going places
microtubule
hydroxyurea

6. In the nucleus after transcitpion and only processed RNA is transporte out of the nucleus
tRNA gripping and going places
Hereditary non polyposis colorectal cancer
DNA/RNA/Protein syntesis direction
RNA processing in eukaryotes occurs

7. Close to - far from or even within (in an intron) the gene whose expression it regulates
Enhancers and silencer may be located_____
kinesin
Tetracyclines
Cilia structure

8. Has enough energy to created the peptide bond
tRNA aminoacylation
the tRNA- amino acid bond
AUG codes For what in prokaryotes
Enhancer

9. Splicing out of introns
C- G bond
Gag on pure gold
Step Three of RNA processing
Rough ER

10. 3 sodium out for 2 potassium in (nout - kin)takes 1 atp and the machine is phosphorylated during the machine cycle
CDKs
Sodium K ATPase
capped and tail transcript is called
frame shift

11. Methionine - which may be removed before translation is completed
nucleosid
In eukaryotes the starting amino acid is...
What type of collagen is most affected in Ehlers Danlos
CDKs

12. (A - G) 2 rings Pure As Gold
Gag on pure gold
unambiguous
Protein synthesis initiation
Purines

13. Asymmetric fluid bilayer - contains - cholesterol - phospholipids - sphingoplipids - glycolipids - and protiends
Step one of RNA processing
missense mutation
Plasma membrane composition
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by

14. Inhibit formation of the initation complex and cause misreading of mRNA
Example of permanent cells
Collagedn synthesis where?
Aminoglycosides
Deamination of cytosine makes

15. RER translation of collagen alpha chains (preprocollagen) usually Gly-X-Y
Permanent cells
the tRNA- amino acid bond
transition
Collagedn synthesis where?

16. H1 string
transition
RNA processing in eukaryotes occurs
Ehlers Danlos
What ties teh nucleosome together

17. UGA - UAG - UAA
Going APE
Xeroderma pigmentosum
nonsense
mRNA stop codons

18. Inhibits bacterials dihydrofolate reducatese down thymine
Rough ER
Protein synthesis is in which direction
Exons
trimethoprim

19. Exocytose procollagen into extracellylar sace
Excocytosis of collagen
Macrolides
alpha amintin
cytokeratin

20. Unwinds DNA template at replication fork
Oubain
helicase
Alports syndrome
trimethoprim

21. Never go to Go divide rapidly with short G1 bone marrow - gut epithelium - skin - hair follicles
Elastin is broken down by
Ehlers Danlos
missense mutation
Labile

22. Type III
desmin
What type of collagen is most affected in Ehlers Danlos
Kartageners syndrome
GFAP

23. Negatively charged DNA loops twice around histone octamers create a nucloesome bead.
tRNA Structure
chromatin structure
Macrolides
Methotrexate

24. 5 prime to 3 prime
Aminoacylt - tRNA synthetase
mRNA is syntehsized in which direction?
DNA pol I
Which end of the nucleotide has the triphosphate

25. The 3 prime hydroxyl of the nascent chain is the target
Step one of RNA processing
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
Which end of a growing DNA strand is the target
Example of permanent cells

26. Enter G1 from G0 when stimulated Hepatocytes/lymphocytes
Stable (quiescent)
Eukaroytes
RNA processing in eukaryotes occurs
Chediak Higashi syndrome

27. Trimming removal of n or c terminal propeptides from zymogens to generate mature proteinds
Protein synthesis initiation
Post - translational modifications
microtubule
Non homologous end joining

28. 2 H bonds greater GC content greater melting point
commaless - non - overlapping
A- T
Loading tRNA on to ribosome energy requirement
Chloramphenicol

29. Intervening noncoding segments of DNA
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
actin and myosin
Introns
Where do introns and exons stay

30. Anit helminth - act on microtubules
Fluoroquinolones
Mebendazole/thiabendazole
AUG codes For what in prokaryotes
Going APE

31. 1) primary transcript combines with snRNPs and other proteins to form spliceosome 2) lariat shaped intermediate is generated 3) Lariat is removed and released to precisely join 2 exons
Steps in splicing
step two of RNA processing
Higher the cholesterol or long saturated fatty acid content
Eukaroytes

32. H1
mRNA stop codons
Kartageners syndrome
Example of permanent cells
The only histone not on the core

33. Stretch of DNA that alters gene expression by binding transcription factors
capped and tail transcript is called
Enhancer
What ties teh nucleosome together
Immunohistochemical stains vimentin

34. RNA polymerase I makes rRNA - RNA pol II makes mRNA - RNA pol III makes tRNA
Non homologous end joining
nonsense
Elastase is inhibited by
RNA polymerases in eukaryotes

35. Substituting a pyramidine for a pyrimadine
purines
transition
Mebendazole/thiabendazole
missense mutation

36. 4 high enrgy bonds
Proofreading function in eukaryotic RNA
Total energy expenditure requirement for translocation
transversion
alpha amintin

37. Makes an RNA primer on which DNA polymerase II can initiate replication
Primase
Elongation
Functional organization of the gene
Step Three of RNA processing

38. Prokaryotic only. Elongates leading strand by adding deoxynucleotides to the 3prime end. Elongates laggin strand. 3 prime to 5 prime exonuclease activity
Alternate splicing
DNA pol III
origin of replication
Total energy expenditure requirement for translocation

39. Responsible for the accuracy of amino acid selection
DNA/RNA/Protein syntesis direction
Non homologous end joining
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
mRNA start codons

40. Hydroxy proline and hydroxylysine
Elastase is inhibited by
Heterochromatin
Hydroxylation of which amino acids are attached to Glycine to form collagen
DNA pol III

41. Phosphorylation - glycosloation - hyderoxylation
C- G bond
Collagen
Covalent alterations
silent mutation

42. Prophas - metaphase - anaphase telophase
tRNA activation
Cell cycle order
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
Order of mitosis

43. Neurons - skeletal - and cardiac muscle - RBCs
Termination
Example of permanent cells
desmin
Base excision repair

44. Inhibits the atpase which increases intracellular sodium which increases intracellular calcium increases cardiaccontractility
actin and myosin
Order of mitosis
Digoxin (cardiac glycosides)
Chediak Higashi syndrome

45. Base + ribose
Exons
alpha amintin
nucleosid
kinesin

46. MRNA
Cilia structure
hydroxyurea
capped and tail transcript is called
kinesin

47. Change resulting in early stop codon
Nucleotide excision repair
nonsense
tRNA aminoacylation
microtubule

48. Codes for formyl methionine (f - Met)
Going APE
Axonemal dyenin
Outside the cell what processing must be done in procolalgen
AUG codes For what in prokaryotes

49. Mutation in nucleotide excision repair Dry skin with melanoma and other cancers
Kartageners syndrome
Xeroderma pigmentosum
Which is the most and least abundant type of RNA
Molecular motor protiesn

50. Anti breast cancer - acts on mts
Paclitaxil
helicase
Griseofulvin
Which is the most and least abundant type of RNA

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First Aid: Biochemistry Molecular

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