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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Must be both activated and inactivated for cell cycle to progress
Loading tRNA on to ribosome energy requirement
Cyclin - CDK
AUG codes For what in prokaryotes
Pyrimidines
2. The 3 prime end
promoter
Proofreading function in eukaryotic RNA
Elastase is inhibited by
Which end of the tRNA is the amino acid bound to?
3. RER translation of collagen alpha chains (preprocollagen) usually Gly-X-Y
Collagedn synthesis where?
A- T
pyrimadines
Exons
4. 1P (blocked by tetracycline)
Gag on pure gold
Vincristine/Vinblastine
Clindamycin
Loading tRNA on to ribosome energy requirement
5. (A - G) 2 rings Pure As Gold
Order of mitosis
Xeroderma pigmentosum
Cholchicine
Purines
6. 2 H bonds greater GC content greater melting point
A- T
Enhancers and silencer may be located_____
Example of permanent cells
capped and tail transcript is called
7. You glyucosolate hte pro - alpha chain lysine resudens and form procollagen (triple helix of alpha chains)
nucleosid
Chediak Higashi syndrome
Glycosolation
cytokeratin
8. Base + ribose
Translocation
Immunohistochemical stains vimentin
missense mutation
nucleosid
9. Prokaryotic only. Elongates leading strand by adding deoxynucleotides to the 3prime end. Elongates laggin strand. 3 prime to 5 prime exonuclease activity
Step Three of RNA processing
Osteogenesis Imperfecta
Clindamycin
DNA pol III
10. Specific glycosylases recognize and remove damaged bases - AP endonuclease cuts DNA at pyrimidne site - empty sugar is removed and the gap is filled and resealed
Labile
DNA topoisomerases
Axonemal dyenin
Base excision repair
11. HS1 - HSB - H2 - H4
Xeroderma pigmentosum
histone octamer names
Smooth ER
DNA/RNA/Protein syntesis direction
12. Anti breast cancer - acts on mts
Smooth ER
Which is the most and least abundant type of RNA
6MP
Paclitaxil
13. Antigout - acts on mts
Hereditary non polyposis colorectal cancer
tRNA activation
DNA ligase
Cholchicine
14. Unmethylated - newly synthesized string is recognized - mismatched nucleotides are removed and the gap is filled and resealed
tRNA activation
Where do introns and exons stay
Exons
Mismatch repair
15. Rampant - Massive - TIny rRNA is most common - then mRNA and then tRNA
Osteogenesis Imperfecta
Step one of RNA processing
Which is the most and least abundant type of RNA
Functional organization of the gene
16. Anti cancer - act on microtubules
Exons
Vincristine/Vinblastine
Fluoroquinolones
RNA polymerases in eukaryotes
17. Unattached to any membrane; site of cytosolic and organeller prtoeins
What type of collagen is most affected in Ehlers Danlos
In eukaryotes the starting amino acid is...
Protein synthesis is in which direction
Free ribosomes
18. ATP ase that links peripheral 9 doublets and causes bending of cilium by differential sliding of doublets
Alternate splicing
Heterochromatin
methionine is only encoded by
Axonemal dyenin
19. Connective tissue
Immunohistochemical stains vimentin
Rough ER
tRNA activation
Collagen
20. Brings together 2 ends of DNA fragments no requirement for homology
DNA pol I
Non homologous end joining
Purines
capped and tail transcript is called
21. Antifungal - act on microtubules
Prokaryote RNA pol
Griseofulvin
actin and myosin
purines
22. Different exons can be combined to make nique protiens in different times
tRNA gripping and going places
Alternate splicing
Deamination of cytosine makes
Guanine has a
23. Vimentin - desmin - cytockeratin - glial fibrillary acid proteins - neurofilaments
Purines
intermediate filaments
Prokaryotes
Labile
24. Site where negative regulators bind
Silencer
Hereditary non polyposis colorectal cancer
Heterochromatin
Protein synthesis initiation
25. Tansport cellular cargo toward opposite ends of microtubule tracks
Outside the cell what processing must be done in procolalgen
Molecular motor protiesn
White codon is at the 3 prime end of a tRNA
Euchromatin
26. Epithelial cells
Which end of a growing DNA strand is the target
cytokeratin
Axonemal dyenin
Enhancer
27. Bm - kidney - ears and eyes
Type IV collagen is an important structural component of...
desmin
Elastin is broken down by
Termination
28. Anit helminth - act on microtubules
Mebendazole/thiabendazole
CDKs
kinesin
What ties teh nucleosome together
29. Substituting a pyramidine for a pyrimadine
transition
Cyclin - CDK
Cyclins
Prokaryote RNA pol
30. Mutation in nucleotide excision repair Dry skin with melanoma and other cancers
Glycosolation
A- T
Xeroderma pigmentosum
Enhancer
31. Change resulting in early stop codon
nonsense
GFAP
cytokeratin
tRNA
32. Completed protein is released from ribosme through simple hydrolosis and dissociates
Paclitaxil
Termination
Where do introns and exons stay
Silencer
33. Attachment of ubiquitin to defective proteinds to tag them for breakdown
Excocytosis of collagen
Proteosomal degradation
the tRNA- amino acid bond
Outside the cell what processing must be done in procolalgen
34. Poly adenylation
transition
Cholchicine
step two of RNA processing
Methotrexate
35. Binds 50S blocking translocation
Hereditary non polyposis colorectal cancer
Guanine has a
Clindamycin
Eukaroytes
36. P53 and RB normally inhibit g1 to S progression
Tumor Suppressors
Excocytosis of collagen
Where do introns and exons stay
Total energy expenditure requirement for translocation
37. Checkpoints control transition between phases of cell cycle. regulated by cyclins - CDKs and tumor suppressors. Mitosis (shortest phse)
Smooth ER
DNA pol I
Cell cycle
In eukaryotes the starting amino acid is...
38. Changed aaconservative - new aa is similar in chemical structure
missense mutation
promoter
Proteosomal degradation
Paclitaxil
39. Neuroglia
microtubule
alpha amintin
A- T
GFAP
40. Stretch of DNA that alters gene expression by binding transcription factors
Elastase is inhibited by
tRNA aminoacylation
Enhancer
tRNA Structure
41. Elastase
Enhancer
Collagen
Elastin is broken down by
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
42. Phosphorylation - glycosloation - hyderoxylation
Protein synthesis initiation
commaless - non - overlapping
Immunohistochemical stains vimentin
Covalent alterations
43. Change resulting in misreading of all nucleotides downstream - usually resulting in a truncated non functional protien
dyenin
pyrimadines
frame shift
Hereditary non polyposis colorectal cancer
44. Be So Totatally Cool Read Books (bOne - CarTWOlage - Threeticular - Type IV under the floor)
transition
Collagen
polyadenylation does/does not require a template
Hereditary non polyposis colorectal cancer
45. Proline - glycine
mRNA start codons
Common amino acids in elastin
Step Three of RNA processing
Stable (quiescent)
46. Promoter - enhancer - promoter - TATA- transcription initiation site - coding region (including exons and introns) and then the AATAAA
Tetracyclines
5FU
mRNA start codons
Functional organization of the gene
47. 9+2 arrangement of microtubules -
Base excision repair
Cilia structure
Aminoglycosides
Enhancers and silencer may be located_____
48. Create a nick in the helix to relieve supercoils created during replication
Ehlers Danlos
DNA topoisomerases
dyenin
Rough ER
49. The 3 prime hydroxyl of the nascent chain is the target
Which end of a growing DNA strand is the target
tRNA
Hereditary non polyposis colorectal cancer
Digoxin (cardiac glycosides)
50. The 5prime end (energy for the bond)
pyrimadines
Which end of the nucleotide has the triphosphate
Clindamycin
Mebendazole/thiabendazole