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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Asymmetric fluid bilayer - contains - cholesterol - phospholipids - sphingoplipids - glycolipids - and protiends
Mismatch repair
Thymine has a
Nucleotide excision repair
Plasma membrane composition
2. Site of dteroid synthesis and detoxification of druigs and poisons (liver hepatocytes and steroid horomore adrenal cortex)
Aminoglycosides
missense mutation
Smooth ER
Promoter mutation
3. Condensed - transciptionally inactive HC- Highly condensed
mRNA stop codons
Order of mitosis
Heterochromatin
Cyclin - CDK
4. Vimentin - desmin - cytockeratin - glial fibrillary acid proteins - neurofilaments
Hydroxylation of which amino acids are attached to Glycine to form collagen
frame shift
Free ribosomes
intermediate filaments
5. Specific glycosylases recognize and remove damaged bases - AP endonuclease cuts DNA at pyrimidne site - empty sugar is removed and the gap is filled and resealed
Deamination of cytosine makes
Free ribosomes
Base excision repair
Neurofilaments
6. Methionine - which may be removed before translation is completed
Alternate splicing
transversion
origin of replication
In eukaryotes the starting amino acid is...
7. CUT 1 ring Cut the Py
Euchromatin
Labile
Pyrimidines
Type IV collagen is an important structural component of...
8. Neurons - skeletal - and cardiac muscle - RBCs
Example of permanent cells
Loading tRNA on to ribosome energy requirement
A- T
single stranded binding proteinds
9. 4 high enrgy bonds
Total energy expenditure requirement for translocation
Cell cycle order
Ehlers Danlos
Protein synthesis initiation
10. Bm - kidney - ears and eyes
Type IV collagen is an important structural component of...
Plasma membrane composition
step two of RNA processing
Collagen
11. Antifungal - act on microtubules
Griseofulvin
In eukaryotes the starting amino acid is...
Elongation
promoter
12. Lysine/hydroxylysine and combines to form collagen
Proteosomal degradation
Tropocollagen cross links between_____ to form____
DNA pol III
Glycosolation
13. Commonly results in dramatic decrease in amount of gene transcribed
Sodium K ATPase
GFAP
Promoter mutation
Permanent cells
14. Enter G1 from G0 when stimulated Hepatocytes/lymphocytes
Enhancers and silencer may be located_____
Alternate splicing
Stable (quiescent)
universal
15. Changed aaconservative - new aa is similar in chemical structure
Alports syndrome
missense mutation
Protein synthesis initiation
nonsense
16. Responsible for the accuracy of amino acid selection
Chediak Higashi syndrome
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
Ehlers Danlos
Heterochromatin
17. Codes for formyl methionine (f - Met)
AUG codes For what in prokaryotes
Stable (quiescent)
Nucleotide excision repair
Euchromatin
18. Substituting a pyramidine for a pyrimadine
5FU
Plasma membrane composition
Oubain
transition
19. Genetic bone disorder (brittle bone disease) type 1 colalgen - fractures (during birth) 2) Blue sclerae 3) hearing loss 4) dental imperfections 1:10000 may be confused with child abuse
Clindamycin
A- T
dyenin
Osteogenesis Imperfecta
20. Intervening noncoding segments of DNA
Introns
Proofreading function in eukaryotic RNA
Promoter mutation
Post - translational modifications
21. Prokaryotic only. Elongates leading strand by adding deoxynucleotides to the 3prime end. Elongates laggin strand. 3 prime to 5 prime exonuclease activity
Cell cycle order
Type IV collagen is an important structural component of...
DNA pol III
Order of mitosis
22. Nucleotide excision repair - Base Excision repair - Mismath repair
mRNA start codons
Single Strand DNA Repair types
tRNA Structure
Common amino acids in elastin
23. In the nucleus after transcitpion and only processed RNA is transporte out of the nucleus
helicase
RNA processing in eukaryotes occurs
Heterochromatin
Oubain
24. H1
Order of mitosis
The only histone not on the core
single stranded binding proteinds
Base excision repair
25. Immotile cilia due to a dyenin arm defect. Results in male nad female inferticility (sperm immotile) - bronchiectasis - and recurrent sinusisits - associated with situs inversus
Enhancers and silencer may be located_____
The only histone not on the core
nonsense
Kartageners syndrome
26. Inhibit DNA gyrase (specific prokaryotic topoisomerase)
tRNA Structure
Fluoroquinolones
Methotrexate
Covalent alterations
27. Hydroxy proline and hydroxylysine
Heterochromatin
kinesin
Tumor Suppressors
Hydroxylation of which amino acids are attached to Glycine to form collagen
28. Retrograde to microtubules
Which end of the tRNA is the amino acid bound to?
universal
dyenin
Deamination of cytosine makes
29. One codon AUG
DNA topoisomerases
frame shift
methionine is only encoded by
Total energy expenditure requirement for translocation
30. Inhibits the atpase which increases intracellular sodium which increases intracellular calcium increases cardiaccontractility
helicase
Digoxin (cardiac glycosides)
actin and myosin
capped and tail transcript is called
31. Tansport cellular cargo toward opposite ends of microtubule tracks
Kartageners syndrome
Excocytosis of collagen
Molecular motor protiesn
Replication fork
32. Activated by GTP hydrolosis initiation factors help assembel the 40 S ribosomal subunites with the initiatior tRNA and are released whent he mRNA and the ribosomal subunit assemple with the complex
What does the hydroxylation of proline and lysine require
Step Three of RNA processing
Protein synthesis initiation
step two of RNA processing
33. Ribonucleotide reductase
Which end of a growing DNA strand is the target
Covalent alterations
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
Step Three of RNA processing
34. Inhibits by binding to the potassium side
origin of replication
Oubain
The only histone not on the core
Silencer
35. Methyl THYmine has a meTHYl
Thymine has a
Order of mitosis
Exons
Promoter mutation
36. Hn RNA
origin of replication
Loading tRNA on to ribosome energy requirement
Euchromatin
Initial transcript without processing is known as
37. Close to - far from or even within (in an intron) the gene whose expression it regulates
kinesin
Enhancers and silencer may be located_____
CDKs
Which end of the nucleotide has the triphosphate
38. Inhibit formation of the initation complex and cause misreading of mRNA
RNA processing in eukaryotes occurs
Associations of Ehlers Danlos
Aminoglycosides
purines
39. Never go to Go divide rapidly with short G1 bone marrow - gut epithelium - skin - hair follicles
Labile
Tetracyclines
transversion
Where do introns and exons stay
40. Inhibits ribonucleotide reductase
Gag on pure gold
Aminoacylt - tRNA synthetase
Kartageners syndrome
hydroxyurea
41. 1 RNA polymerase (multisubunite complex) makes all 3 kinds of RNA
Which end of the nucleotide has the triphosphate
microtubule
5FU
Prokaryote RNA pol
42. Made from orogate precuror with PRPP added later
capped and tail transcript is called
Kartageners syndrome
pyrimadines
Prokaryote RNA pol
43. Rampant - Massive - TIny rRNA is most common - then mRNA and then tRNA
Which is the most and least abundant type of RNA
Translocation
Aminoglycosides
mRNA stop codons
44. A site - incoming aminoacyl tRNA - Psite accomodates growing Peptide - E site holds EmplytRNA as it exits
Xeroderma pigmentosum
Going APE
Neurofilaments
mRNA is syntehsized in which direction?
45. Negatively charged DNA loops twice around histone octamers create a nucloesome bead.
the tRNA- amino acid bond
chromatin structure
Xeroderma pigmentosum
Protein synthesis initiation
46. Inhibits dihydrofolate reductase down thymine
Collagen
capped and tail transcript is called
Associations of Ehlers Danlos
Methotrexate
47. Be So Totatally Cool Read Books (bOne - CarTWOlage - Threeticular - Type IV under the floor)
CDKs
trimethoprim
Collagen
Guanine has a
48. 3 sodium out for 2 potassium in (nout - kin)takes 1 atp and the machine is phosphorylated during the machine cycle
Which end of the nucleotide has the triphosphate
Steps in splicing
Sodium K ATPase
Molecular motor protiesn
49. Inhibits 50S peptidyl transferase
Initial transcript without processing is known as
Higher the cholesterol or long saturated fatty acid content
Elastase is inhibited by
Chloramphenicol
50. AD and AR- associated iwth joint dislocation - berry aneurysms - organ rupture
Associations of Ehlers Danlos
RNA processing in eukaryotes occurs
trimethoprim
Enhancers and silencer may be located_____