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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Bm - kidney - ears and eyes
silent mutation
pyrimadines
Type IV collagen is an important structural component of...
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
2. Site of secretory protiens (mucus secreting goblet cells and antibody secreting cells)
Tetracyclines
Protein synthesis is in which direction
Rough ER
What type of collagen is most affected in Ehlers Danlos
3. Introns stay In the nucleus whereas EXons EXit and are EXpressed
purines
capped and tail transcript is called
single stranded binding proteinds
Where do introns and exons stay
4. Bind 30S subunit preventing attachment of aminoacyl - tRNA
Labile
Tetracyclines
What does the hydroxylation of proline and lysine require
Osteogenesis Imperfecta
5. Three amino acids necessary for purine synthesis= glutamine - aspartate and glycine
Deamination of cytosine makes
DNA ligase
Axonemal dyenin
Gag on pure gold
6. Non homologous end joining
transition
promoter
Cilia structure
Double Strand DNA repair
7. Ribonucleotide reductase
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
nonsense
alpha amintin
Hydroxylation of which amino acids are attached to Glycine to form collagen
8. MRNA
Paclitaxil
Stable (quiescent)
Glycosolation
capped and tail transcript is called
9. Never go to Go divide rapidly with short G1 bone marrow - gut epithelium - skin - hair follicles
actin and myosin
Labile
Digoxin (cardiac glycosides)
Double Strand DNA repair
10. The N to C
Protein synthesis is in which direction
Double Strand DNA repair
chromatin structure
universal
11. Antifungal - act on microtubules
Protein synthesis initiation
Which end of the nucleotide has the triphosphate
Griseofulvin
Which end of a growing DNA strand is the target
12. GTP
Guanine has a
capped and tail transcript is called
Permanent cells
tRNA gripping and going places
13. Methyl THYmine has a meTHYl
tRNA
Guanine has a
Thymine has a
A- T
14. 9+2 arrangement of microtubules -
Thymine has a
Cilia structure
nonsense
intermediate filaments
15. Does not
Sodium K ATPase
polyadenylation does/does not require a template
Translocation
Replication fork
16. Made from IMP precursor
Nucleotide excision repair
nonsense
Which end of the nucleotide has the triphosphate
purines
17. Read froma fixed starting point as a continous sequenecs of bases
dyenin
The only histone not on the core
Aminoacylt - tRNA synthetase
commaless - non - overlapping
18. Changed aaconservative - new aa is similar in chemical structure
Elongation
Tumor Suppressors
Total energy expenditure requirement for translocation
missense mutation
19. Substituting a pyramidine for a pyrimadine
transition
the tRNA- amino acid bond
Replication fork
methionine is only encoded by
20. Connective tissue
Cell cycle order
Alports syndrome
Immunohistochemical stains vimentin
Total energy expenditure requirement for translocation
21. ATP ase that links peripheral 9 doublets and causes bending of cilium by differential sliding of doublets
Common amino acids in elastin
Nucleotide excision repair
Macrolides
Axonemal dyenin
22. Checkpoints control transition between phases of cell cycle. regulated by cyclins - CDKs and tumor suppressors. Mitosis (shortest phse)
Chloramphenicol
Vincristine/Vinblastine
Base excision repair
Cell cycle
23. Methionine - which may be removed before translation is completed
kinesin
In eukaryotes the starting amino acid is...
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
DNA/RNA/Protein syntesis direction
24. Attachment of ubiquitin to defective proteinds to tag them for breakdown
Proteosomal degradation
What ties teh nucleosome together
Molecular motor protiesn
actin and myosin
25. The 5prime end (energy for the bond)
the tRNA- amino acid bond
Hereditary non polyposis colorectal cancer
Which end of the nucleotide has the triphosphate
commaless - non - overlapping
26. Capping on 5 prime end (7 methylguanosine) -
hydroxyurea
Neurofilaments
Step one of RNA processing
trimethoprim
27. Inhibit DNA gyrase (specific prokaryotic topoisomerase)
Chediak Higashi syndrome
Fluoroquinolones
Replication fork
Protein synthesis initiation
28. Xlinked recessive IV collagen bm - kidney - ear and eye -- nephritis and defness ocular disturbances
DNA pol I
Alports syndrome
Gag on pure gold
Cyclins
29. Be So Totatally Cool Read Books (bOne - CarTWOlage - Threeticular - Type IV under the floor)
Collagen
Cilia structure
kinesin
step two of RNA processing
30. 1P (blocked by tetracycline)
Functional organization of the gene
Step Three of RNA processing
Loading tRNA on to ribosome energy requirement
desmin
31. H1
Collagedn synthesis where?
Macrolides
Osteogenesis Imperfecta
The only histone not on the core
32. Inhibits ribonucleotide reductase
microtubule
hydroxyurea
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
dyenin
33. Anit helminth - act on microtubules
Mebendazole/thiabendazole
mRNA start codons
Elastase is inhibited by
Heterochromatin
34. Genetic bone disorder (brittle bone disease) type 1 colalgen - fractures (during birth) 2) Blue sclerae 3) hearing loss 4) dental imperfections 1:10000 may be confused with child abuse
Tropocollagen cross links between_____ to form____
Cell cycle order
Free ribosomes
Osteogenesis Imperfecta
35. Unmethylated - newly synthesized string is recognized - mismatched nucleotides are removed and the gap is filled and resealed
RNA processing in eukaryotes occurs
Mismatch repair
DNA pol I
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
36. Site where negative regulators bind
Silencer
alpha amintin
Step Three of RNA processing
Elastase is inhibited by
37. Contain the actual genetic information coding for protein
Clindamycin
Exons
frame shift
Cilia structure
38. Uracil
universal
Loading tRNA on to ribosome energy requirement
Deamination of cytosine makes
Post - translational modifications
39. Odd 30S plus 50 S=70S
Prokaryotes
Introns
Non homologous end joining
Proofreading function in eukaryotic RNA
40. Strethchy protein within lungs - large artiers - elastic liaments - vocal cords - ligamenta flava)
Collagen
Nucleotide excision repair
universal
Elastin
41. Prophas - metaphase - anaphase telophase
Digoxin (cardiac glycosides)
Order of mitosis
origin of replication
capped and tail transcript is called
42. Neuroglia
Double Strand DNA repair
GFAP
DNA/RNA/Protein syntesis direction
Base excision repair
43. Condensed - transciptionally inactive HC- Highly condensed
Heterochromatin
Griseofulvin
Immunohistochemical stains vimentin
Associations of Ehlers Danlos
44. Mutation in nucleotide excision repair Dry skin with melanoma and other cancers
tRNA
Xeroderma pigmentosum
the tRNA- amino acid bond
Base excision repair
45. 2 H bonds greater GC content greater melting point
Immunohistochemical stains vimentin
AUG codes For what in prokaryotes
missense mutation
A- T
46. 1 RNA polymerase (multisubunite complex) makes all 3 kinds of RNA
DNA/RNA/Protein syntesis direction
Prokaryote RNA pol
Collagedn synthesis where?
Smooth ER
47. 1P blocked by chloramphenicaol and macrolide
Translocation
Nucleotide excision repair
the tRNA- amino acid bond
transition
48. CCA AT 3 PRIME END
Promoter mutation
White codon is at the 3 prime end of a tRNA
cytokeratin
6MP
49. One codon AUG
Enhancer
Griseofulvin
methionine is only encoded by
Step one of RNA processing
50. Retrograde to microtubules
tRNA
promoter
Proofreading function in eukaryotic RNA
dyenin