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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Enter G1 from G0 when stimulated Hepatocytes/lymphocytes
Which end of the tRNA is the amino acid bound to?
Order of mitosis
Aminoacylt - tRNA synthetase
Stable (quiescent)
2. (A - G) 2 rings Pure As Gold
Non homologous end joining
silent mutation
Purines
Axonemal dyenin
3. Responsible for the accuracy of amino acid selection
silent mutation
Going APE
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
chromatin structure
4. AD and AR- associated iwth joint dislocation - berry aneurysms - organ rupture
Elastin
Cyclins
Associations of Ehlers Danlos
histone octamer names
5. Prokaryotic only. Elongates leading strand by adding deoxynucleotides to the 3prime end. Elongates laggin strand. 3 prime to 5 prime exonuclease activity
mRNA start codons
Sodium K ATPase
Mebendazole/thiabendazole
DNA pol III
6. Inhibits ribonucleotide reductase
Alternate splicing
hydroxyurea
Enhancers and silencer may be located_____
Thymine has a
7. Cylindrical structure composed of helical array of plymerized dimers of alpha and beta tubulin - flagella - cilia - mitotic spindle - grows slowly collapses quickly
microtubule
Functional organization of the gene
Exons
Cell cycle order
8. Rampant - Massive - TIny rRNA is most common - then mRNA and then tRNA
Common amino acids in elastin
Cell cycle
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
Which is the most and least abundant type of RNA
9. A site - incoming aminoacyl tRNA - Psite accomodates growing Peptide - E site holds EmplytRNA as it exits
Tetracyclines
Going APE
Termination
What does the hydroxylation of proline and lysine require
10. Attachment of ubiquitin to defective proteinds to tag them for breakdown
silent mutation
C- G bond
Proteosomal degradation
Going APE
11. P53 and RB normally inhibit g1 to S progression
Purines
Tumor Suppressors
intermediate filaments
Collagedn synthesis where?
12. UGA - UAG - UAA
Collagedn synthesis where?
Termination
mRNA stop codons
Type IV collagen is an important structural component of...
13. Scrutinizes aa before and after it binds to tRNA. If incorrect bond is hydrolyzed.
Ehlers Danlos
Aminoacylt - tRNA synthetase
Tetracyclines
Single Strand DNA Repair types
14. MRNA
Purines
capped and tail transcript is called
DNA ligase
frame shift
15. Cleave terminal regions of procollagen to transform into insoluable tropocolagen
Hydroxylation of which amino acids are attached to Glycine to form collagen
Chloramphenicol
Outside the cell what processing must be done in procolalgen
A- T
16. Non homologous end joining
Aminoglycosides
Prokaryotes
Double Strand DNA repair
Osteogenesis Imperfecta
17. Even 40S 60S =80S
The only histone not on the core
What ties teh nucleosome together
Which end of the nucleotide has the triphosphate
Eukaroytes
18. Bind 30S subunit preventing attachment of aminoacyl - tRNA
Labile
Tetracyclines
DNA pol I
Protein synthesis is in which direction
19. Intervening noncoding segments of DNA
Cilia structure
Introns
Cell cycle order
Termination
20. Site where RNA polymerase and multiple other transciption factors bind to DNA upstream from gene locus (AT rich upstream sequence with TATA and CAAT boxes)
Sodium K ATPase
Higher the cholesterol or long saturated fatty acid content
Tetracyclines
promoter
21. Aminoacyl - tRNA binds to A site 2) peptidyltransferase catalyzes peptide bond formation transfers growing polypeptie to amino acid in A site 3) ribosome advances 3 nucleotides toward the 3 prime end of RNA moving peptiydyl RNA to P site
Elongation
Protein synthesis is in which direction
Associations of Ehlers Danlos
tRNA aminoacylation
22. 1) primary transcript combines with snRNPs and other proteins to form spliceosome 2) lariat shaped intermediate is generated 3) Lariat is removed and released to precisely join 2 exons
single stranded binding proteinds
Macrolides
Guanine has a
Steps in splicing
23. Type III
Common amino acids in elastin
What type of collagen is most affected in Ehlers Danlos
polyadenylation does/does not require a template
Promoter mutation
24. Contain the actual genetic information coding for protein
Exons
Clindamycin
Promoter mutation
DNA ligase
25. Unwinds DNA template at replication fork
Prokaryotes
Elastase is inhibited by
the tRNA- amino acid bond
helicase
26. 75-90 nucleotides - 2ary structure cloverleaf form anticodon end is opposite 3 prime aminoacyl end
transition
tRNA Structure
intermediate filaments
Cyclin - CDK
27. 5 prime to 3 prime
silent mutation
Step Three of RNA processing
mRNA is syntehsized in which direction?
Hydroxylation of which amino acids are attached to Glycine to form collagen
28. Three amino acids necessary for purine synthesis= glutamine - aspartate and glycine
Kartageners syndrome
Gag on pure gold
actin and myosin
Axonemal dyenin
29. Made from orogate precuror with PRPP added later
pyrimadines
Exons
Where do introns and exons stay
Paclitaxil
30. Methyl THYmine has a meTHYl
Paclitaxil
White codon is at the 3 prime end of a tRNA
Thymine has a
Prokaryote RNA pol
31. 1P blocked by chloramphenicaol and macrolide
Mismatch repair
Translocation
histone octamer names
nucleosid
32. Hn RNA
Aminoacylt - tRNA synthetase
tRNA gripping and going places
RNA polymerases in eukaryotes
Initial transcript without processing is known as
33. Anti breast cancer - acts on mts
Paclitaxil
Protein synthesis initiation
hydroxyurea
Base excision repair
34. Antigout - acts on mts
In eukaryotes the starting amino acid is...
Cholchicine
silent mutation
Alports syndrome
35. 2 H bonds greater GC content greater melting point
Outside the cell what processing must be done in procolalgen
commaless - non - overlapping
Which end of the tRNA is the amino acid bound to?
A- T
36. Must be both activated and inactivated for cell cycle to progress
Cyclin - CDK
DNA pol III
Hydroxylation of which amino acids are attached to Glycine to form collagen
actin and myosin
37. Inhibits the atpase which increases intracellular sodium which increases intracellular calcium increases cardiaccontractility
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
A- T
Digoxin (cardiac glycosides)
mRNA stop codons
38. Negatively charged DNA loops twice around histone octamers create a nucloesome bead.
chromatin structure
kinesin
Pyrimidines
methionine is only encoded by
39. Commonly results in dramatic decrease in amount of gene transcribed
Initial transcript without processing is known as
Protein synthesis initiation
Purines
Promoter mutation
40. Strethchy protein within lungs - large artiers - elastic liaments - vocal cords - ligamenta flava)
Elastin
Cell cycle
microtubule
pyrimadines
41. Binds 50S blocking translocation
Clindamycin
Free ribosomes
nucleosid
The only histone not on the core
42. Faulty collagen synthesis causing 1) hyperextensible skin 2) tendency to bleed 3) hypermobile joints
Ehlers Danlos
step two of RNA processing
Outside the cell what processing must be done in procolalgen
Which end of the tRNA is the amino acid bound to?
43. Inhibits by binding to the potassium side
histone octamer names
Oubain
Associations of Ehlers Danlos
Collagedn synthesis where?
44. In the nucleus after transcitpion and only processed RNA is transporte out of the nucleus
Cyclins
RNA processing in eukaryotes occurs
Osteogenesis Imperfecta
universal
45. 1 RNA polymerase (multisubunite complex) makes all 3 kinds of RNA
Immunohistochemical stains vimentin
microtubule
Initial transcript without processing is known as
Prokaryote RNA pol
46. The 3 prime end
Proofreading function in eukaryotic RNA
Steps in splicing
intermediate filaments
Which end of the tRNA is the amino acid bound to?
47. Base + ribose
Steps in splicing
transition
nucleosid
frame shift
48. Proline - glycine
Common amino acids in elastin
Xeroderma pigmentosum
Exons
Excocytosis of collagen
49. Genetic code is conserved throughout evolution
universal
Type IV collagen is an important structural component of...
capped and tail transcript is called
Rough ER
50. Prokaryotic only. Degrades RNA primer and fills in the gap with DNA (5 prime to 3 prime exonuclease)
What does the hydroxylation of proline and lysine require
Cholchicine
DNA pol I
Osteogenesis Imperfecta