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First Aid: Biochemistry Molecular

Instructions:
  • Answer 50 questions in 15 minutes.
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  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Cyclin depndent kinases; consituative and inactive






2. More than 1 codon may code for the same amino acid






3. 1) primary transcript combines with snRNPs and other proteins to form spliceosome 2) lariat shaped intermediate is generated 3) Lariat is removed and released to precisely join 2 exons






4. 3 sodium out for 2 potassium in (nout - kin)takes 1 atp and the machine is phosphorylated during the machine cycle






5. H1 string






6. Made from orogate precuror with PRPP added later






7. One codon AUG






8. Capping on 5 prime end (7 methylguanosine) -






9. Genetic bone disorder (brittle bone disease) type 1 colalgen - fractures (during birth) 2) Blue sclerae 3) hearing loss 4) dental imperfections 1:10000 may be confused with child abuse






10. Nucleotide excision repair - Base Excision repair - Mismath repair






11. Promoter - enhancer - promoter - TATA- transcription initiation site - coding region (including exons and introns) and then the AATAAA






12. Connective tissue






13. Checkpoints control transition between phases of cell cycle. regulated by cyclins - CDKs and tumor suppressors. Mitosis (shortest phse)






14. 2 H bonds greater GC content greater melting point






15. Methionine - which may be removed before translation is completed






16. Lysine/hydroxylysine and combines to form collagen






17. Substituting a purine for a pyrimdine or vice versa






18. Change resulting in misreading of all nucleotides downstream - usually resulting in a truncated non functional protien






19. Inhibits thymidylate synthase down thymine






20. Negatively charged DNA loops twice around histone octamers create a nucloesome bead.






21. Base + ribose






22. Seals






23. Alpha 1 antitrypisn






24. Inhibit formation of the initation complex and cause misreading of mRNA






25. 1P blocked by chloramphenicaol and macrolide






26. H1






27. Introns stay In the nucleus whereas EXons EXit and are EXpressed






28. Never go to Go divide rapidly with short G1 bone marrow - gut epithelium - skin - hair follicles






29. Retrograde to microtubules






30. Blocks denovo purine synthesis






31. Neuroglia






32. Contain the actual genetic information coding for protein






33. Changed aaconservative - new aa is similar in chemical structure






34. Substituting a pyramidine for a pyrimadine






35. Y shaped region along DNA template where leading and lagging strands are syntehsized






36. Splicing out of introns






37. 9+2 arrangement of microtubules -






38. Prokaryotic only. Degrades RNA primer and fills in the gap with DNA (5 prime to 3 prime exonuclease)






39. Proline - glycine






40. Ketone






41. Be So Totatally Cool Read Books (bOne - CarTWOlage - Threeticular - Type IV under the floor)






42. Different exons can be combined to make nique protiens in different times






43. Rampant - Massive - TIny rRNA is most common - then mRNA and then tRNA






44. Intervening noncoding segments of DNA






45. Microtubule polymerization defect resulting in lowered phagocytosis. results in recurrent pyogenic infections - partial albinism and peripheral neuropathy






46. ATP ase that links peripheral 9 doublets and causes bending of cilium by differential sliding of doublets






47. Unattached to any membrane; site of cytosolic and organeller prtoeins






48. Uracil






49. Activated by GTP hydrolosis initiation factors help assembel the 40 S ribosomal subunites with the initiatior tRNA and are released whent he mRNA and the ribosomal subunit assemple with the complex






50. Asymmetric fluid bilayer - contains - cholesterol - phospholipids - sphingoplipids - glycolipids - and protiends