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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Create a nick in the helix to relieve supercoils created during replication
DNA ligase
DNA topoisomerases
Labile
Axonemal dyenin
2. Site where negative regulators bind
kinesin
tRNA activation
Silencer
Gag on pure gold
3. Base + ribose
transition
A- T
nucleosid
In eukaryotes the starting amino acid is...
4. A site - incoming aminoacyl tRNA - Psite accomodates growing Peptide - E site holds EmplytRNA as it exits
hydroxyurea
Silencer
Going APE
Tropocollagen cross links between_____ to form____
5. RNA polymerase I makes rRNA - RNA pol II makes mRNA - RNA pol III makes tRNA
frame shift
purines
RNA polymerases in eukaryotes
Alternate splicing
6. Regulatory proteins that control cell cycle events; phase specific; activated CDKs
Cyclins
Clindamycin
Guanine has a
Rough ER
7. Never go to Go divide rapidly with short G1 bone marrow - gut epithelium - skin - hair follicles
Macrolides
Associations of Ehlers Danlos
Cyclins
Labile
8. Introns stay In the nucleus whereas EXons EXit and are EXpressed
Initial transcript without processing is known as
Thymine has a
transition
Where do introns and exons stay
9. Antigout - acts on mts
Common amino acids in elastin
tRNA Structure
Cholchicine
Prokaryote RNA pol
10. Substituting a pyramidine for a pyrimadine
Translocation
transition
Elastase is inhibited by
Mebendazole/thiabendazole
11. Change resulting in early stop codon
Steps in splicing
Where do introns and exons stay
Post - translational modifications
nonsense
12. Methyl THYmine has a meTHYl
Pyrimidines
Clindamycin
Proofreading function in eukaryotic RNA
Thymine has a
13. Each codon specifies only 1 amino acid
unambiguous
DNA ligase
Enhancers and silencer may be located_____
Heterochromatin
14. Genetic bone disorder (brittle bone disease) type 1 colalgen - fractures (during birth) 2) Blue sclerae 3) hearing loss 4) dental imperfections 1:10000 may be confused with child abuse
Going APE
Enhancers and silencer may be located_____
the tRNA- amino acid bond
Osteogenesis Imperfecta
15. Brings together 2 ends of DNA fragments no requirement for homology
Thymine has a
Non homologous end joining
White codon is at the 3 prime end of a tRNA
DNA ligase
16. Capping on 5 prime end (7 methylguanosine) -
Clindamycin
histone octamer names
Macrolides
Step one of RNA processing
17. Lysine/hydroxylysine and combines to form collagen
What does the hydroxylation of proline and lysine require
5FU
the tRNA- amino acid bond
Tropocollagen cross links between_____ to form____
18. Blocks denovo purine synthesis
cytokeratin
Promoter mutation
6MP
DNA topoisomerases
19. Mutation in nucleotide excision repair Dry skin with melanoma and other cancers
Eukaroytes
origin of replication
Xeroderma pigmentosum
hydroxyurea
20. Unattached to any membrane; site of cytosolic and organeller prtoeins
In eukaryotes the starting amino acid is...
Hydroxylation of which amino acids are attached to Glycine to form collagen
tRNA aminoacylation
Free ribosomes
21. Attachment of ubiquitin to defective proteinds to tag them for breakdown
Free ribosomes
Proteosomal degradation
Axonemal dyenin
Immunohistochemical stains vimentin
22. Binds 50S blocking translocation
Enhancer
A- T
Which is the most and least abundant type of RNA
Clindamycin
23. RER translation of collagen alpha chains (preprocollagen) usually Gly-X-Y
Excocytosis of collagen
Clindamycin
Collagedn synthesis where?
Order of mitosis
24. Cyclin depndent kinases; consituative and inactive
CDKs
Macrolides
Step Three of RNA processing
Covalent alterations
25. Three amino acids necessary for purine synthesis= glutamine - aspartate and glycine
Collagen
Gag on pure gold
Elastin is broken down by
degenerate or redundant
26. ATP
nucleosid
Termination
Plasma membrane composition
tRNA activation
27. Muscle
Initial transcript without processing is known as
nucleotide
tRNA gripping and going places
desmin
28. Prokaryotic only. Elongates leading strand by adding deoxynucleotides to the 3prime end. Elongates laggin strand. 3 prime to 5 prime exonuclease activity
RNA processing in eukaryotes occurs
DNA pol III
Step Three of RNA processing
Prokaryote RNA pol
29. (A - G) 2 rings Pure As Gold
DNA/RNA/Protein syntesis direction
nucleotide
Purines
Initial transcript without processing is known as
30. A malfunction of mismatch repair (MUt L etc..)
Stable (quiescent)
Hereditary non polyposis colorectal cancer
unambiguous
Prokaryote RNA pol
31. Ribonucleotide reductase
Termination
Nucleotide excision repair
Elastin
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
32. Epithelial cells
What type of collagen is most affected in Ehlers Danlos
Smooth ER
Cell cycle order
cytokeratin
33. Made from orogate precuror with PRPP added later
Aminoglycosides
Paclitaxil
Mismatch repair
pyrimadines
34. Inhbits RNA pol II (found in death cap mushrooms)
tRNA activation
What does the hydroxylation of proline and lysine require
alpha amintin
Neurofilaments
35. Nucleotide excision repair - Base Excision repair - Mismath repair
Single Strand DNA Repair types
Proteosomal degradation
nucleotide
Loading tRNA on to ribosome energy requirement
36. In the nucleus after transcitpion and only processed RNA is transporte out of the nucleus
Enhancer
trimethoprim
Osteogenesis Imperfecta
RNA processing in eukaryotes occurs
37. VItamin C
Gag on pure gold
nucleosid
Outside the cell what processing must be done in procolalgen
What does the hydroxylation of proline and lysine require
38. Connective tissue
desmin
Alports syndrome
Immunohistochemical stains vimentin
Chloramphenicol
39. Inhibit DNA gyrase (specific prokaryotic topoisomerase)
Glycosolation
dyenin
Kartageners syndrome
Fluoroquinolones
40. HS1 - HSB - H2 - H4
Alports syndrome
histone octamer names
Cyclins
Enhancers and silencer may be located_____
41. Seals
Digoxin (cardiac glycosides)
promoter
DNA ligase
dyenin
42. Trimming removal of n or c terminal propeptides from zymogens to generate mature proteinds
White codon is at the 3 prime end of a tRNA
Free ribosomes
Tropocollagen cross links between_____ to form____
Post - translational modifications
43. 75-90 nucleotides - 2ary structure cloverleaf form anticodon end is opposite 3 prime aminoacyl end
transversion
GFAP
intermediate filaments
tRNA Structure
44. Prophas - metaphase - anaphase telophase
Associations of Ehlers Danlos
tRNA
Double Strand DNA repair
Order of mitosis
45. 2 H bonds greater GC content greater melting point
Silencer
A- T
desmin
Protein synthesis is in which direction
46. Made from IMP precursor
purines
Tropocollagen cross links between_____ to form____
Prokaryotes
Proteosomal degradation
47. Vimentin - desmin - cytockeratin - glial fibrillary acid proteins - neurofilaments
Cyclin - CDK
Protein synthesis initiation
origin of replication
intermediate filaments
48. Uracil
Prokaryotes
Deamination of cytosine makes
missense mutation
Base excision repair
49. Inhibits the atpase which increases intracellular sodium which increases intracellular calcium increases cardiaccontractility
polyadenylation does/does not require a template
actin and myosin
Digoxin (cardiac glycosides)
Euchromatin
50. Site of dteroid synthesis and detoxification of druigs and poisons (liver hepatocytes and steroid horomore adrenal cortex)
Smooth ER
Cell cycle
Glycosolation
Steps in splicing