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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Cilia - glagella - mitotic spindle - neurons - centrioles
Chloramphenicol
Elongation
Going APE
microtubule
2. 1 RNA polymerase (multisubunite complex) makes all 3 kinds of RNA
Prokaryote RNA pol
Chloramphenicol
histone octamer names
DNA/RNA/Protein syntesis direction
3. CCA AT 3 PRIME END
Cyclins
White codon is at the 3 prime end of a tRNA
tRNA aminoacylation
kinesin
4. Bm - kidney - ears and eyes
Protein synthesis initiation
White codon is at the 3 prime end of a tRNA
Type IV collagen is an important structural component of...
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
5. Immotile cilia due to a dyenin arm defect. Results in male nad female inferticility (sperm immotile) - bronchiectasis - and recurrent sinusisits - associated with situs inversus
Alports syndrome
DNA topoisomerases
mRNA is syntehsized in which direction?
Kartageners syndrome
6. Asymmetric fluid bilayer - contains - cholesterol - phospholipids - sphingoplipids - glycolipids - and protiends
Plasma membrane composition
tRNA activation
Rough ER
C- G bond
7. Antigout - acts on mts
helicase
Higher the cholesterol or long saturated fatty acid content
Cholchicine
tRNA gripping and going places
8. Faulty collagen synthesis causing 1) hyperextensible skin 2) tendency to bleed 3) hypermobile joints
Xeroderma pigmentosum
dyenin
Ehlers Danlos
tRNA
9. Contain the actual genetic information coding for protein
DNA ligase
Exons
desmin
Fluoroquinolones
10. AUG inAUGurates protein synthesis
mRNA start codons
Nucleotide excision repair
Macrolides
tRNA
11. Genetic bone disorder (brittle bone disease) type 1 colalgen - fractures (during birth) 2) Blue sclerae 3) hearing loss 4) dental imperfections 1:10000 may be confused with child abuse
Osteogenesis Imperfecta
Macrolides
Smooth ER
Prokaryote RNA pol
12. 75-90 nucleotides - 2ary structure cloverleaf form anticodon end is opposite 3 prime aminoacyl end
tRNA Structure
Heterochromatin
mRNA stop codons
Digoxin (cardiac glycosides)
13. 1P blocked by chloramphenicaol and macrolide
the tRNA- amino acid bond
Which is the most and least abundant type of RNA
Translocation
RNA polymerases in eukaryotes
14. Y shaped region along DNA template where leading and lagging strands are syntehsized
Ehlers Danlos
Purines
Prokaryotes
Replication fork
15. Change resulting in misreading of all nucleotides downstream - usually resulting in a truncated non functional protien
Xeroderma pigmentosum
DNA pol III
DNA/RNA/Protein syntesis direction
frame shift
16. Alpha 1 antitrypisn
desmin
Elastase is inhibited by
kinesin
Oubain
17. Different exons can be combined to make nique protiens in different times
Cyclin - CDK
Aminoglycosides
Alternate splicing
DNA pol III
18. Completed protein is released from ribosme through simple hydrolosis and dissociates
Free ribosomes
Osteogenesis Imperfecta
Termination
helicase
19. Lysine/hydroxylysine and combines to form collagen
Tropocollagen cross links between_____ to form____
tRNA aminoacylation
Proteosomal degradation
Collagedn synthesis where?
20. Seals
Griseofulvin
Enhancers and silencer may be located_____
DNA ligase
alpha amintin
21. Muscle
Oubain
Heterochromatin
desmin
Protein synthesis initiation
22. 2 H bonds greater GC content greater melting point
Base excision repair
Proofreading function in eukaryotic RNA
A- T
Vincristine/Vinblastine
23. 3 sodium out for 2 potassium in (nout - kin)takes 1 atp and the machine is phosphorylated during the machine cycle
Cyclin - CDK
cytokeratin
methionine is only encoded by
Sodium K ATPase
24. Checkpoints control transition between phases of cell cycle. regulated by cyclins - CDKs and tumor suppressors. Mitosis (shortest phse)
Cell cycle
Collagen
Macrolides
tRNA activation
25. Ketone
Elastin
Methotrexate
Termination
Guanine has a
26. Inhibits by binding to the potassium side
Loading tRNA on to ribosome energy requirement
helicase
Oubain
Chloramphenicol
27. In the nucleus after transcitpion and only processed RNA is transporte out of the nucleus
Enhancers and silencer may be located_____
tRNA Structure
trimethoprim
RNA processing in eukaryotes occurs
28. Tansport cellular cargo toward opposite ends of microtubule tracks
Heterochromatin
tRNA Structure
Protein synthesis is in which direction
Molecular motor protiesn
29. 1P (blocked by tetracycline)
Plasma membrane composition
capped and tail transcript is called
Loading tRNA on to ribosome energy requirement
Which end of the nucleotide has the triphosphate
30. Prokaryotic only. Degrades RNA primer and fills in the gap with DNA (5 prime to 3 prime exonuclease)
DNA pol I
Permanent cells
5FU
Functional organization of the gene
31. 1) primary transcript combines with snRNPs and other proteins to form spliceosome 2) lariat shaped intermediate is generated 3) Lariat is removed and released to precisely join 2 exons
Initial transcript without processing is known as
Steps in splicing
Chloramphenicol
actin and myosin
32. The 5prime end (energy for the bond)
Which end of the nucleotide has the triphosphate
tRNA aminoacylation
Example of permanent cells
Step one of RNA processing
33. Codes for formyl methionine (f - Met)
5FU
the tRNA- amino acid bond
Prokaryotes
AUG codes For what in prokaryotes
34. Promoter - enhancer - promoter - TATA- transcription initiation site - coding region (including exons and introns) and then the AATAAA
Functional organization of the gene
Purines
Going APE
Alports syndrome
35. Base+ribose+phosphate linked by a phosphodiester bond
Higher the cholesterol or long saturated fatty acid content
nucleotide
DNA ligase
Which is the most and least abundant type of RNA
36. Remain in G0 regenerate from stem cells
Tropocollagen cross links between_____ to form____
Permanent cells
Mismatch repair
Elastin
37. Microvilli - muscle contraction - cytokinesis - adhering juntions
nonsense
Enhancer
actin and myosin
transversion
38. Neurons - skeletal - and cardiac muscle - RBCs
Fluoroquinolones
Example of permanent cells
polyadenylation does/does not require a template
Cell cycle order
39. Specific endonucleases release the oligonucleotide containing damaged bases. DNA polymerase and logase fill and resealt eh gap
Griseofulvin
Nucleotide excision repair
commaless - non - overlapping
Labile
40. Odd 30S plus 50 S=70S
Smooth ER
Prokaryotes
Single Strand DNA Repair types
Cilia structure
41. Bind 30S subunit preventing attachment of aminoacyl - tRNA
Tetracyclines
Elastin
single stranded binding proteinds
Cyclins
42. Be So Totatally Cool Read Books (bOne - CarTWOlage - Threeticular - Type IV under the floor)
Collagen
Cyclin - CDK
Enhancer
Chloramphenicol
43. RER translation of collagen alpha chains (preprocollagen) usually Gly-X-Y
Fluoroquinolones
Collagedn synthesis where?
Methotrexate
missense mutation
44. Prokaryotic only. Elongates leading strand by adding deoxynucleotides to the 3prime end. Elongates laggin strand. 3 prime to 5 prime exonuclease activity
Tetracyclines
DNA pol III
Step one of RNA processing
Higher the cholesterol or long saturated fatty acid content
45. Anit helminth - act on microtubules
What type of collagen is most affected in Ehlers Danlos
purines
Mebendazole/thiabendazole
5FU
46. A malfunction of mismatch repair (MUt L etc..)
mRNA is syntehsized in which direction?
Hereditary non polyposis colorectal cancer
transition
nonsense
47. Microtubule polymerization defect resulting in lowered phagocytosis. results in recurrent pyogenic infections - partial albinism and peripheral neuropathy
Aminoacylt - tRNA synthetase
Chediak Higashi syndrome
Molecular motor protiesn
Cyclin - CDK
48. Exocytose procollagen into extracellylar sace
Excocytosis of collagen
promoter
hydroxyurea
DNA ligase
49. Phosphorylation - glycosloation - hyderoxylation
desmin
Order of mitosis
Covalent alterations
Where do introns and exons stay
50. Hn RNA
Initial transcript without processing is known as
A- T
C- G bond
intermediate filaments