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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Odd 30S plus 50 S=70S
Prokaryotes
Tetracyclines
microtubule
Which end of the nucleotide has the triphosphate
2. Prophas - metaphase - anaphase telophase
single stranded binding proteinds
Order of mitosis
step two of RNA processing
Cilia structure
3. Cilia - glagella - mitotic spindle - neurons - centrioles
Base excision repair
microtubule
Proteosomal degradation
Functional organization of the gene
4. 9+2 arrangement of microtubules -
The only histone not on the core
Associations of Ehlers Danlos
Cilia structure
Enhancer
5. Genetic bone disorder (brittle bone disease) type 1 colalgen - fractures (during birth) 2) Blue sclerae 3) hearing loss 4) dental imperfections 1:10000 may be confused with child abuse
Promoter mutation
tRNA aminoacylation
Osteogenesis Imperfecta
origin of replication
6. Nucleotide excision repair - Base Excision repair - Mismath repair
nonsense
Elongation
Permanent cells
Single Strand DNA Repair types
7. Vimentin - desmin - cytockeratin - glial fibrillary acid proteins - neurofilaments
intermediate filaments
Loading tRNA on to ribosome energy requirement
Labile
Griseofulvin
8. RNA polymerase I makes rRNA - RNA pol II makes mRNA - RNA pol III makes tRNA
Guanine has a
frame shift
Collagen
RNA polymerases in eukaryotes
9. Inhibits the atpase which increases intracellular sodium which increases intracellular calcium increases cardiaccontractility
Digoxin (cardiac glycosides)
Hydroxylation of which amino acids are attached to Glycine to form collagen
What does the hydroxylation of proline and lysine require
Base excision repair
10. The 5prime end (energy for the bond)
intermediate filaments
Vincristine/Vinblastine
degenerate or redundant
Which end of the nucleotide has the triphosphate
11. Ribonucleotide reductase
transversion
Type IV collagen is an important structural component of...
Heterochromatin
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
12. Base + ribose
origin of replication
Labile
Purines
nucleosid
13. Three amino acids necessary for purine synthesis= glutamine - aspartate and glycine
Higher the cholesterol or long saturated fatty acid content
Gag on pure gold
Enhancers and silencer may be located_____
What ties teh nucleosome together
14. Activated by GTP hydrolosis initiation factors help assembel the 40 S ribosomal subunites with the initiatior tRNA and are released whent he mRNA and the ribosomal subunit assemple with the complex
Molecular motor protiesn
Protein synthesis initiation
Covalent alterations
mRNA stop codons
15. ATP- AMP (2 phosphoanhydride bonds)
Gag on pure gold
Silencer
Macrolides
tRNA aminoacylation
16. Completed protein is released from ribosme through simple hydrolosis and dissociates
Step Three of RNA processing
Single Strand DNA Repair types
missense mutation
Termination
17. Methionine - which may be removed before translation is completed
Smooth ER
In eukaryotes the starting amino acid is...
tRNA Structure
Purines
18. Xlinked recessive IV collagen bm - kidney - ear and eye -- nephritis and defness ocular disturbances
Gag on pure gold
alpha amintin
RNA processing in eukaryotes occurs
Alports syndrome
19. Asymmetric fluid bilayer - contains - cholesterol - phospholipids - sphingoplipids - glycolipids - and protiends
missense mutation
Plasma membrane composition
Hydroxylation of which amino acids are attached to Glycine to form collagen
Protein synthesis is in which direction
20. Made from orogate precuror with PRPP added later
commaless - non - overlapping
Which end of the nucleotide has the triphosphate
pyrimadines
Proteosomal degradation
21. Checkpoints control transition between phases of cell cycle. regulated by cyclins - CDKs and tumor suppressors. Mitosis (shortest phse)
White codon is at the 3 prime end of a tRNA
Cell cycle
Xeroderma pigmentosum
missense mutation
22. 1P blocked by chloramphenicaol and macrolide
Silencer
Labile
Translocation
Total energy expenditure requirement for translocation
23. Base+ribose+phosphate linked by a phosphodiester bond
tRNA gripping and going places
nucleotide
What ties teh nucleosome together
Example of permanent cells
24. Cleave terminal regions of procollagen to transform into insoluable tropocolagen
In eukaryotes the starting amino acid is...
mRNA is syntehsized in which direction?
tRNA gripping and going places
Outside the cell what processing must be done in procolalgen
25. Scrutinizes aa before and after it binds to tRNA. If incorrect bond is hydrolyzed.
Common amino acids in elastin
Aminoacylt - tRNA synthetase
polyadenylation does/does not require a template
universal
26. AUG inAUGurates protein synthesis
Which is the most and least abundant type of RNA
helicase
mRNA start codons
A- T
27. Tansport cellular cargo toward opposite ends of microtubule tracks
Example of permanent cells
Molecular motor protiesn
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
Which end of a growing DNA strand is the target
28. Microtubule polymerization defect resulting in lowered phagocytosis. results in recurrent pyogenic infections - partial albinism and peripheral neuropathy
Total energy expenditure requirement for translocation
6MP
Post - translational modifications
Chediak Higashi syndrome
29. 1 RNA polymerase (multisubunite complex) makes all 3 kinds of RNA
Nucleotide excision repair
Cell cycle
In eukaryotes the starting amino acid is...
Prokaryote RNA pol
30. Intervening noncoding segments of DNA
Going APE
Introns
step two of RNA processing
Nucleotide excision repair
31. 3 sodium out for 2 potassium in (nout - kin)takes 1 atp and the machine is phosphorylated during the machine cycle
Digoxin (cardiac glycosides)
Sodium K ATPase
mRNA stop codons
Fluoroquinolones
32. Attachment of ubiquitin to defective proteinds to tag them for breakdown
cytokeratin
Proteosomal degradation
Alports syndrome
Initial transcript without processing is known as
33. RER translation of collagen alpha chains (preprocollagen) usually Gly-X-Y
the tRNA- amino acid bond
Collagedn synthesis where?
RNA processing in eukaryotes occurs
helicase
34. GTP
histone octamer names
tRNA gripping and going places
hydroxyurea
Steps in splicing
35. In the nucleus after transcitpion and only processed RNA is transporte out of the nucleus
Alports syndrome
GFAP
RNA processing in eukaryotes occurs
mRNA start codons
36. CCA AT 3 PRIME END
tRNA activation
microtubule
methionine is only encoded by
White codon is at the 3 prime end of a tRNA
37. Antifungal - act on microtubules
Deamination of cytosine makes
Macrolides
Enhancer
Griseofulvin
38. Neurons
Clindamycin
Common amino acids in elastin
Neurofilaments
alpha amintin
39. 1) primary transcript combines with snRNPs and other proteins to form spliceosome 2) lariat shaped intermediate is generated 3) Lariat is removed and released to precisely join 2 exons
commaless - non - overlapping
DNA pol III
dyenin
Steps in splicing
40. Seals
DNA ligase
mRNA stop codons
Mebendazole/thiabendazole
dyenin
41. Faulty collagen synthesis causing 1) hyperextensible skin 2) tendency to bleed 3) hypermobile joints
microtubule
Clindamycin
What ties teh nucleosome together
Ehlers Danlos
42. 1P (blocked by tetracycline)
Molecular motor protiesn
tRNA
Macrolides
Loading tRNA on to ribosome energy requirement
43. Be So Totatally Cool Read Books (bOne - CarTWOlage - Threeticular - Type IV under the floor)
Collagen
Proteosomal degradation
Stable (quiescent)
Type IV collagen is an important structural component of...
44. Hydroxy proline and hydroxylysine
helicase
Hydroxylation of which amino acids are attached to Glycine to form collagen
Total energy expenditure requirement for translocation
Pyrimidines
45. Unattached to any membrane; site of cytosolic and organeller prtoeins
Outside the cell what processing must be done in procolalgen
Covalent alterations
Free ribosomes
microtubule
46. Less condensed - transciptionally active=eu truly transcobed
Tumor Suppressors
Euchromatin
DNA pol I
Tropocollagen cross links between_____ to form____
47. Contain the actual genetic information coding for protein
Chloramphenicol
Alternate splicing
Steps in splicing
Exons
48. Regulatory proteins that control cell cycle events; phase specific; activated CDKs
Clindamycin
Cyclins
Cell cycle
Total energy expenditure requirement for translocation
49. Strethchy protein within lungs - large artiers - elastic liaments - vocal cords - ligamenta flava)
Clindamycin
Elastin
chromatin structure
transition
50. Proline - glycine
Neurofilaments
Common amino acids in elastin
chromatin structure
Purines