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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Enter G1 from G0 when stimulated Hepatocytes/lymphocytes
Hereditary non polyposis colorectal cancer
Griseofulvin
Stable (quiescent)
trimethoprim
2. Particular sequnece in genomre where DNA replication begins. May be single (prokaryotes) or multiple (eukaryotes)
helicase
Total energy expenditure requirement for translocation
trimethoprim
origin of replication
3. One codon AUG
Steps in splicing
DNA ligase
nucleotide
methionine is only encoded by
4. Cylindrical structure composed of helical array of plymerized dimers of alpha and beta tubulin - flagella - cilia - mitotic spindle - grows slowly collapses quickly
Step Three of RNA processing
Alports syndrome
Tropocollagen cross links between_____ to form____
microtubule
5. Scrutinizes aa before and after it binds to tRNA. If incorrect bond is hydrolyzed.
Aminoacylt - tRNA synthetase
GFAP
Exons
tRNA
6. Completed protein is released from ribosme through simple hydrolosis and dissociates
Where do introns and exons stay
nucleosid
Covalent alterations
Termination
7. Three amino acids necessary for purine synthesis= glutamine - aspartate and glycine
Ehlers Danlos
Gag on pure gold
microtubule
Which end of the nucleotide has the triphosphate
8. Specific glycosylases recognize and remove damaged bases - AP endonuclease cuts DNA at pyrimidne site - empty sugar is removed and the gap is filled and resealed
Higher the cholesterol or long saturated fatty acid content
Base excision repair
Protein synthesis is in which direction
silent mutation
9. Anti breast cancer - acts on mts
purines
Stable (quiescent)
Alports syndrome
Paclitaxil
10. Aminoacyl - tRNA binds to A site 2) peptidyltransferase catalyzes peptide bond formation transfers growing polypeptie to amino acid in A site 3) ribosome advances 3 nucleotides toward the 3 prime end of RNA moving peptiydyl RNA to P site
DNA topoisomerases
Replication fork
Hereditary non polyposis colorectal cancer
Elongation
11. The 3 prime end
Which end of the tRNA is the amino acid bound to?
tRNA Structure
Post - translational modifications
Hereditary non polyposis colorectal cancer
12. Bm - kidney - ears and eyes
Type IV collagen is an important structural component of...
Glycosolation
Proteosomal degradation
Deamination of cytosine makes
13. Be So Totatally Cool Read Books (bOne - CarTWOlage - Threeticular - Type IV under the floor)
Collagen
frame shift
Sodium K ATPase
Step Three of RNA processing
14. Inhibits the atpase which increases intracellular sodium which increases intracellular calcium increases cardiaccontractility
Kartageners syndrome
purines
Hydroxylation of which amino acids are attached to Glycine to form collagen
Digoxin (cardiac glycosides)
15. Ketone
transition
DNA pol I
desmin
Guanine has a
16. Inhibit DNA gyrase (specific prokaryotic topoisomerase)
tRNA activation
Elongation
Chloramphenicol
Fluoroquinolones
17. Different exons can be combined to make nique protiens in different times
Alternate splicing
hydroxyurea
missense mutation
RNA processing in eukaryotes occurs
18. Activated by GTP hydrolosis initiation factors help assembel the 40 S ribosomal subunites with the initiatior tRNA and are released whent he mRNA and the ribosomal subunit assemple with the complex
Axonemal dyenin
Protein synthesis initiation
Collagedn synthesis where?
Common amino acids in elastin
19. Inhibits by binding to the potassium side
intermediate filaments
Oubain
Higher the cholesterol or long saturated fatty acid content
Covalent alterations
20. Retrograde to microtubules
hydroxyurea
Excocytosis of collagen
dyenin
Going APE
21. 1 RNA polymerase (multisubunite complex) makes all 3 kinds of RNA
Prokaryote RNA pol
capped and tail transcript is called
Kartageners syndrome
Rough ER
22. Greater melting temperature lower fluidity
tRNA gripping and going places
Cell cycle order
universal
Higher the cholesterol or long saturated fatty acid content
23. Close to - far from or even within (in an intron) the gene whose expression it regulates
Enhancers and silencer may be located_____
Neurofilaments
GFAP
Collagen
24. The N to C
mRNA stop codons
missense mutation
Hereditary non polyposis colorectal cancer
Protein synthesis is in which direction
25. HS1 - HSB - H2 - H4
Loading tRNA on to ribosome energy requirement
histone octamer names
Cell cycle order
Labile
26. Neurons - skeletal - and cardiac muscle - RBCs
helicase
Base excision repair
Example of permanent cells
Termination
27. Each codon specifies only 1 amino acid
actin and myosin
unambiguous
purines
Cilia structure
28. Bind 50S blocking translocation
Protein synthesis is in which direction
Macrolides
Methotrexate
Clindamycin
29. Genetic bone disorder (brittle bone disease) type 1 colalgen - fractures (during birth) 2) Blue sclerae 3) hearing loss 4) dental imperfections 1:10000 may be confused with child abuse
Osteogenesis Imperfecta
Axonemal dyenin
Stable (quiescent)
Elongation
30. G1 - S - G2 - Mitosis
Cell cycle order
Clindamycin
Going APE
Oubain
31. Immotile cilia due to a dyenin arm defect. Results in male nad female inferticility (sperm immotile) - bronchiectasis - and recurrent sinusisits - associated with situs inversus
Guanine has a
mRNA is syntehsized in which direction?
White codon is at the 3 prime end of a tRNA
Kartageners syndrome
32. Less condensed - transciptionally active=eu truly transcobed
Prokaryote RNA pol
Euchromatin
universal
Termination
33. RER translation of collagen alpha chains (preprocollagen) usually Gly-X-Y
Alports syndrome
CDKs
Eukaroytes
Collagedn synthesis where?
34. Xlinked recessive IV collagen bm - kidney - ear and eye -- nephritis and defness ocular disturbances
Smooth ER
Promoter mutation
Alports syndrome
Prokaryote RNA pol
35. You glyucosolate hte pro - alpha chain lysine resudens and form procollagen (triple helix of alpha chains)
unambiguous
Euchromatin
transversion
Glycosolation
36. Specific endonucleases release the oligonucleotide containing damaged bases. DNA polymerase and logase fill and resealt eh gap
Elongation
Chediak Higashi syndrome
Nucleotide excision repair
DNA ligase
37. Muscle
desmin
Methotrexate
Kartageners syndrome
Alports syndrome
38. Commonly results in dramatic decrease in amount of gene transcribed
Excocytosis of collagen
Which end of the tRNA is the amino acid bound to?
Promoter mutation
Example of permanent cells
39. Changed aaconservative - new aa is similar in chemical structure
Neurofilaments
Step one of RNA processing
missense mutation
Eukaroytes
40. Seals
Type IV collagen is an important structural component of...
Higher the cholesterol or long saturated fatty acid content
DNA ligase
Guanine has a
41. Change resulting in misreading of all nucleotides downstream - usually resulting in a truncated non functional protien
Associations of Ehlers Danlos
Which end of the tRNA is the amino acid bound to?
Cyclins
frame shift
42. Microtubule polymerization defect resulting in lowered phagocytosis. results in recurrent pyogenic infections - partial albinism and peripheral neuropathy
Labile
Which is the most and least abundant type of RNA
Chediak Higashi syndrome
Vincristine/Vinblastine
43. Same aa often base change in 3rd position of codon
silent mutation
universal
Smooth ER
Single Strand DNA Repair types
44. 1P blocked by chloramphenicaol and macrolide
Translocation
actin and myosin
Protein synthesis is in which direction
Cyclin - CDK
45. Made from orogate precuror with PRPP added later
Double Strand DNA repair
Cyclin - CDK
pyrimadines
Steps in splicing
46. AUG inAUGurates protein synthesis
Kartageners syndrome
mRNA start codons
In eukaryotes the starting amino acid is...
Plasma membrane composition
47. Checkpoints control transition between phases of cell cycle. regulated by cyclins - CDKs and tumor suppressors. Mitosis (shortest phse)
Tumor Suppressors
Axonemal dyenin
Cell cycle
Molecular motor protiesn
48. Inhibits dihydrofolate reductase down thymine
RNA processing in eukaryotes occurs
Methotrexate
intermediate filaments
Type IV collagen is an important structural component of...
49. Mutation in nucleotide excision repair Dry skin with melanoma and other cancers
Xeroderma pigmentosum
Nucleotide excision repair
universal
Thymine has a
50. A site - incoming aminoacyl tRNA - Psite accomodates growing Peptide - E site holds EmplytRNA as it exits
Silencer
Going APE
Prokaryote RNA pol
Type IV collagen is an important structural component of...