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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Retrograde to microtubules
dyenin
Elongation
A- T
Type IV collagen is an important structural component of...
2. HS1 - HSB - H2 - H4
histone octamer names
Aminoglycosides
Macrolides
Griseofulvin
3. Immotile cilia due to a dyenin arm defect. Results in male nad female inferticility (sperm immotile) - bronchiectasis - and recurrent sinusisits - associated with situs inversus
Common amino acids in elastin
DNA topoisomerases
AUG codes For what in prokaryotes
Kartageners syndrome
4. Inhibit DNA gyrase (specific prokaryotic topoisomerase)
Plasma membrane composition
Prokaryotes
AUG codes For what in prokaryotes
Fluoroquinolones
5. Genetic code is conserved throughout evolution
Elastin is broken down by
Vincristine/Vinblastine
missense mutation
universal
6. 3 sodium out for 2 potassium in (nout - kin)takes 1 atp and the machine is phosphorylated during the machine cycle
DNA pol III
Aminoglycosides
Sodium K ATPase
Deamination of cytosine makes
7. Cyclin depndent kinases; consituative and inactive
purines
CDKs
silent mutation
DNA/RNA/Protein syntesis direction
8. Methyl THYmine has a meTHYl
Prokaryotes
Sodium K ATPase
DNA topoisomerases
Thymine has a
9. Introns stay In the nucleus whereas EXons EXit and are EXpressed
Where do introns and exons stay
Tropocollagen cross links between_____ to form____
commaless - non - overlapping
Elastin is broken down by
10. More than 1 codon may code for the same amino acid
A- T
universal
degenerate or redundant
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
11. 1) primary transcript combines with snRNPs and other proteins to form spliceosome 2) lariat shaped intermediate is generated 3) Lariat is removed and released to precisely join 2 exons
Higher the cholesterol or long saturated fatty acid content
Stable (quiescent)
Heterochromatin
Steps in splicing
12. Base + ribose
Promoter mutation
tRNA aminoacylation
nucleosid
Replication fork
13. Trimming removal of n or c terminal propeptides from zymogens to generate mature proteinds
Guanine has a
frame shift
AUG codes For what in prokaryotes
Post - translational modifications
14. Microtubule polymerization defect resulting in lowered phagocytosis. results in recurrent pyogenic infections - partial albinism and peripheral neuropathy
silent mutation
Chediak Higashi syndrome
the tRNA- amino acid bond
unambiguous
15. Alpha 1 antitrypisn
frame shift
Gag on pure gold
origin of replication
Elastase is inhibited by
16. The N to C
Mismatch repair
Protein synthesis is in which direction
Cyclins
Neurofilaments
17. Same aa often base change in 3rd position of codon
purines
Clindamycin
trimethoprim
silent mutation
18. Site where RNA polymerase and multiple other transciption factors bind to DNA upstream from gene locus (AT rich upstream sequence with TATA and CAAT boxes)
Molecular motor protiesn
promoter
purines
Stable (quiescent)
19. Made from IMP precursor
Replication fork
Termination
purines
transversion
20. 1 RNA polymerase (multisubunite complex) makes all 3 kinds of RNA
Prokaryote RNA pol
Initial transcript without processing is known as
nucleotide
transition
21. Cylindrical structure composed of helical array of plymerized dimers of alpha and beta tubulin - flagella - cilia - mitotic spindle - grows slowly collapses quickly
tRNA activation
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
microtubule
Alternate splicing
22. Hydroxy proline and hydroxylysine
Hydroxylation of which amino acids are attached to Glycine to form collagen
nonsense
Methotrexate
Double Strand DNA repair
23. Strethchy protein within lungs - large artiers - elastic liaments - vocal cords - ligamenta flava)
Elastin
Nucleotide excision repair
Step Three of RNA processing
single stranded binding proteinds
24. UGA - UAG - UAA
mRNA stop codons
Collagedn synthesis where?
Functional organization of the gene
Eukaroytes
25. Completed protein is released from ribosme through simple hydrolosis and dissociates
purines
Deamination of cytosine makes
tRNA gripping and going places
Termination
26. Type III
GFAP
nonsense
Heterochromatin
What type of collagen is most affected in Ehlers Danlos
27. 1P (blocked by tetracycline)
DNA/RNA/Protein syntesis direction
Loading tRNA on to ribosome energy requirement
actin and myosin
cytokeratin
28. ATP
Example of permanent cells
Kartageners syndrome
tRNA activation
Double Strand DNA repair
29. Faulty collagen synthesis causing 1) hyperextensible skin 2) tendency to bleed 3) hypermobile joints
Ehlers Danlos
Oubain
Chediak Higashi syndrome
degenerate or redundant
30. Muscle
Methotrexate
Total energy expenditure requirement for translocation
desmin
Pyrimidines
31. Anit helminth - act on microtubules
unambiguous
Mebendazole/thiabendazole
Pyrimidines
Replication fork
32. Genetic bone disorder (brittle bone disease) type 1 colalgen - fractures (during birth) 2) Blue sclerae 3) hearing loss 4) dental imperfections 1:10000 may be confused with child abuse
Which end of the nucleotide has the triphosphate
Osteogenesis Imperfecta
Enhancer
Alternate splicing
33. Anterograde to microtubule
the tRNA- amino acid bond
kinesin
Introns
Cell cycle
34. Each codon specifies only 1 amino acid
Tumor Suppressors
unambiguous
Deamination of cytosine makes
Tropocollagen cross links between_____ to form____
35. Inhibits the atpase which increases intracellular sodium which increases intracellular calcium increases cardiaccontractility
Exons
Immunohistochemical stains vimentin
Digoxin (cardiac glycosides)
Chediak Higashi syndrome
36. 1P blocked by chloramphenicaol and macrolide
Translocation
tRNA Structure
Prokaryote RNA pol
Going APE
37. P53 and RB normally inhibit g1 to S progression
tRNA Structure
Termination
Elastase is inhibited by
Tumor Suppressors
38. Specific glycosylases recognize and remove damaged bases - AP endonuclease cuts DNA at pyrimidne site - empty sugar is removed and the gap is filled and resealed
Clindamycin
Macrolides
microtubule
Base excision repair
39. One codon AUG
Methotrexate
DNA topoisomerases
methionine is only encoded by
Glycosolation
40. Xlinked recessive IV collagen bm - kidney - ear and eye -- nephritis and defness ocular disturbances
AUG codes For what in prokaryotes
Excocytosis of collagen
In eukaryotes the starting amino acid is...
Alports syndrome
41. ATP- AMP (2 phosphoanhydride bonds)
Digoxin (cardiac glycosides)
What type of collagen is most affected in Ehlers Danlos
tRNA aminoacylation
Elongation
42. Has enough energy to created the peptide bond
Going APE
Collagen
the tRNA- amino acid bond
degenerate or redundant
43. Anti breast cancer - acts on mts
Paclitaxil
Common amino acids in elastin
What ties teh nucleosome together
Aminoacylt - tRNA synthetase
44. 2 H bonds greater GC content greater melting point
Heterochromatin
Nucleotide excision repair
A- T
Digoxin (cardiac glycosides)
45. Seals
Elastin is broken down by
Fluoroquinolones
Promoter mutation
DNA ligase
46. Unattached to any membrane; site of cytosolic and organeller prtoeins
transition
origin of replication
Purines
Free ribosomes
47. Nucleotide excision repair - Base Excision repair - Mismath repair
Methotrexate
histone octamer names
Single Strand DNA Repair types
What does the hydroxylation of proline and lysine require
48. Inhbits RNA pol II (found in death cap mushrooms)
pyrimadines
Digoxin (cardiac glycosides)
C- G bond
alpha amintin
49. Asymmetric fluid bilayer - contains - cholesterol - phospholipids - sphingoplipids - glycolipids - and protiends
Plasma membrane composition
Labile
Sodium K ATPase
Paclitaxil
50. Hn RNA
Vincristine/Vinblastine
Initial transcript without processing is known as
Covalent alterations
The only histone not on the core