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First Aid: Biochemistry Molecular

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Enter G1 from G0 when stimulated Hepatocytes/lymphocytes






2. Particular sequnece in genomre where DNA replication begins. May be single (prokaryotes) or multiple (eukaryotes)






3. One codon AUG






4. Cylindrical structure composed of helical array of plymerized dimers of alpha and beta tubulin - flagella - cilia - mitotic spindle - grows slowly collapses quickly






5. Scrutinizes aa before and after it binds to tRNA. If incorrect bond is hydrolyzed.






6. Completed protein is released from ribosme through simple hydrolosis and dissociates






7. Three amino acids necessary for purine synthesis= glutamine - aspartate and glycine






8. Specific glycosylases recognize and remove damaged bases - AP endonuclease cuts DNA at pyrimidne site - empty sugar is removed and the gap is filled and resealed






9. Anti breast cancer - acts on mts






10. Aminoacyl - tRNA binds to A site 2) peptidyltransferase catalyzes peptide bond formation transfers growing polypeptie to amino acid in A site 3) ribosome advances 3 nucleotides toward the 3 prime end of RNA moving peptiydyl RNA to P site






11. The 3 prime end






12. Bm - kidney - ears and eyes






13. Be So Totatally Cool Read Books (bOne - CarTWOlage - Threeticular - Type IV under the floor)






14. Inhibits the atpase which increases intracellular sodium which increases intracellular calcium increases cardiaccontractility






15. Ketone






16. Inhibit DNA gyrase (specific prokaryotic topoisomerase)






17. Different exons can be combined to make nique protiens in different times






18. Activated by GTP hydrolosis initiation factors help assembel the 40 S ribosomal subunites with the initiatior tRNA and are released whent he mRNA and the ribosomal subunit assemple with the complex






19. Inhibits by binding to the potassium side






20. Retrograde to microtubules






21. 1 RNA polymerase (multisubunite complex) makes all 3 kinds of RNA






22. Greater melting temperature lower fluidity






23. Close to - far from or even within (in an intron) the gene whose expression it regulates






24. The N to C






25. HS1 - HSB - H2 - H4






26. Neurons - skeletal - and cardiac muscle - RBCs






27. Each codon specifies only 1 amino acid






28. Bind 50S blocking translocation






29. Genetic bone disorder (brittle bone disease) type 1 colalgen - fractures (during birth) 2) Blue sclerae 3) hearing loss 4) dental imperfections 1:10000 may be confused with child abuse






30. G1 - S - G2 - Mitosis






31. Immotile cilia due to a dyenin arm defect. Results in male nad female inferticility (sperm immotile) - bronchiectasis - and recurrent sinusisits - associated with situs inversus






32. Less condensed - transciptionally active=eu truly transcobed






33. RER translation of collagen alpha chains (preprocollagen) usually Gly-X-Y






34. Xlinked recessive IV collagen bm - kidney - ear and eye -- nephritis and defness ocular disturbances






35. You glyucosolate hte pro - alpha chain lysine resudens and form procollagen (triple helix of alpha chains)






36. Specific endonucleases release the oligonucleotide containing damaged bases. DNA polymerase and logase fill and resealt eh gap






37. Muscle






38. Commonly results in dramatic decrease in amount of gene transcribed






39. Changed aaconservative - new aa is similar in chemical structure






40. Seals






41. Change resulting in misreading of all nucleotides downstream - usually resulting in a truncated non functional protien






42. Microtubule polymerization defect resulting in lowered phagocytosis. results in recurrent pyogenic infections - partial albinism and peripheral neuropathy






43. Same aa often base change in 3rd position of codon






44. 1P blocked by chloramphenicaol and macrolide






45. Made from orogate precuror with PRPP added later






46. AUG inAUGurates protein synthesis






47. Checkpoints control transition between phases of cell cycle. regulated by cyclins - CDKs and tumor suppressors. Mitosis (shortest phse)






48. Inhibits dihydrofolate reductase down thymine






49. Mutation in nucleotide excision repair Dry skin with melanoma and other cancers






50. A site - incoming aminoacyl tRNA - Psite accomodates growing Peptide - E site holds EmplytRNA as it exits