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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Exocytose procollagen into extracellylar sace
Excocytosis of collagen
Exons
Guanine has a
DNA pol I
2. Non homologous end joining
Which end of a growing DNA strand is the target
Double Strand DNA repair
Glycosolation
Methotrexate
3. Faulty collagen synthesis causing 1) hyperextensible skin 2) tendency to bleed 3) hypermobile joints
Chediak Higashi syndrome
Ehlers Danlos
microtubule
Enhancer
4. Responsible for the accuracy of amino acid selection
Glycosolation
mRNA stop codons
Proofreading function in eukaryotic RNA
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
5. Antifungal - act on microtubules
Griseofulvin
Enhancer
actin and myosin
DNA topoisomerases
6. The N to C
C- G bond
RNA processing in eukaryotes occurs
Protein synthesis is in which direction
Higher the cholesterol or long saturated fatty acid content
7. Capping on 5 prime end (7 methylguanosine) -
AUG codes For what in prokaryotes
Sodium K ATPase
Step one of RNA processing
microtubule
8. Epithelial cells
GFAP
cytokeratin
Deamination of cytosine makes
microtubule
9. Specific endonucleases release the oligonucleotide containing damaged bases. DNA polymerase and logase fill and resealt eh gap
Nucleotide excision repair
Which is the most and least abundant type of RNA
transition
Elastin is broken down by
10. Remain in G0 regenerate from stem cells
cytokeratin
Thymine has a
Permanent cells
the tRNA- amino acid bond
11. 4 high enrgy bonds
Rough ER
Initial transcript without processing is known as
Total energy expenditure requirement for translocation
Higher the cholesterol or long saturated fatty acid content
12. Site of secretory protiens (mucus secreting goblet cells and antibody secreting cells)
Gag on pure gold
Rough ER
Loading tRNA on to ribosome energy requirement
helicase
13. Substituting a pyramidine for a pyrimadine
Elastase is inhibited by
transition
Prokaryotes
trimethoprim
14. Ribonucleotide reductase
Non homologous end joining
dyenin
Introns
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
15. Close to - far from or even within (in an intron) the gene whose expression it regulates
The only histone not on the core
DNA/RNA/Protein syntesis direction
Enhancers and silencer may be located_____
Which end of the tRNA is the amino acid bound to?
16. Uracil
commaless - non - overlapping
Deamination of cytosine makes
Kartageners syndrome
Initial transcript without processing is known as
17. Microtubule polymerization defect resulting in lowered phagocytosis. results in recurrent pyogenic infections - partial albinism and peripheral neuropathy
Chediak Higashi syndrome
alpha amintin
microtubule
Euchromatin
18. 1P blocked by chloramphenicaol and macrolide
transversion
transition
Translocation
mRNA is syntehsized in which direction?
19. Hn RNA
microtubule
Guanine has a
Where do introns and exons stay
Initial transcript without processing is known as
20. Bind 50S blocking translocation
Eukaroytes
Macrolides
Primase
Going APE
21. Changed aaconservative - new aa is similar in chemical structure
missense mutation
Where do introns and exons stay
RNA polymerases in eukaryotes
Aminoglycosides
22. Three amino acids necessary for purine synthesis= glutamine - aspartate and glycine
Functional organization of the gene
cytokeratin
Initial transcript without processing is known as
Gag on pure gold
23. A site - incoming aminoacyl tRNA - Psite accomodates growing Peptide - E site holds EmplytRNA as it exits
Steps in splicing
DNA pol I
Going APE
Prokaryote RNA pol
24. Poly adenylation
alpha amintin
Higher the cholesterol or long saturated fatty acid content
step two of RNA processing
tRNA aminoacylation
25. Less condensed - transciptionally active=eu truly transcobed
tRNA gripping and going places
frame shift
Euchromatin
Post - translational modifications
26. H1 string
What ties teh nucleosome together
Elongation
Cyclins
Axonemal dyenin
27. Attachment of ubiquitin to defective proteinds to tag them for breakdown
Silencer
Base excision repair
Proteosomal degradation
In eukaryotes the starting amino acid is...
28. Codes for formyl methionine (f - Met)
AUG codes For what in prokaryotes
origin of replication
Associations of Ehlers Danlos
nucleotide
29. Contain the actual genetic information coding for protein
Promoter mutation
Exons
origin of replication
Elastase is inhibited by
30. Site of dteroid synthesis and detoxification of druigs and poisons (liver hepatocytes and steroid horomore adrenal cortex)
Clindamycin
Smooth ER
Eukaroytes
silent mutation
31. ATP
tRNA activation
single stranded binding proteinds
AUG codes For what in prokaryotes
Excocytosis of collagen
32. Specific glycosylases recognize and remove damaged bases - AP endonuclease cuts DNA at pyrimidne site - empty sugar is removed and the gap is filled and resealed
Base excision repair
pyrimadines
Initial transcript without processing is known as
frame shift
33. No proofreading function but can initiate chains. RNA poymerase II opens DNA at promoter site
Proofreading function in eukaryotic RNA
Type IV collagen is an important structural component of...
Kartageners syndrome
The only histone not on the core
34. Checkpoints control transition between phases of cell cycle. regulated by cyclins - CDKs and tumor suppressors. Mitosis (shortest phse)
single stranded binding proteinds
intermediate filaments
Tumor Suppressors
Cell cycle
35. Inhibits the atpase which increases intracellular sodium which increases intracellular calcium increases cardiaccontractility
Cell cycle
hydroxyurea
microtubule
Digoxin (cardiac glycosides)
36. Bind 30S subunit preventing attachment of aminoacyl - tRNA
Elastase is inhibited by
Tetracyclines
step two of RNA processing
Silencer
37. Inhibits bacterials dihydrofolate reducatese down thymine
Single Strand DNA Repair types
Labile
purines
trimethoprim
38. Hydroxy proline and hydroxylysine
Base excision repair
DNA pol I
Hydroxylation of which amino acids are attached to Glycine to form collagen
Chloramphenicol
39. CCA AT 3 PRIME END
GFAP
Where do introns and exons stay
White codon is at the 3 prime end of a tRNA
universal
40. Inhbits RNA pol II (found in death cap mushrooms)
alpha amintin
Termination
Hydroxylation of which amino acids are attached to Glycine to form collagen
RNA processing in eukaryotes occurs
41. Never go to Go divide rapidly with short G1 bone marrow - gut epithelium - skin - hair follicles
White codon is at the 3 prime end of a tRNA
Labile
Outside the cell what processing must be done in procolalgen
A- T
42. Seals
Post - translational modifications
Axonemal dyenin
DNA ligase
degenerate or redundant
43. Asymmetric fluid bilayer - contains - cholesterol - phospholipids - sphingoplipids - glycolipids - and protiends
DNA topoisomerases
Plasma membrane composition
White codon is at the 3 prime end of a tRNA
Silencer
44. Bm - kidney - ears and eyes
Type IV collagen is an important structural component of...
CDKs
capped and tail transcript is called
AUG codes For what in prokaryotes
45. Greater melting temperature lower fluidity
Non homologous end joining
Covalent alterations
Higher the cholesterol or long saturated fatty acid content
Alternate splicing
46. (A - G) 2 rings Pure As Gold
Elastin is broken down by
Purines
6MP
Collagedn synthesis where?
47. More than 1 codon may code for the same amino acid
Mismatch repair
Ehlers Danlos
degenerate or redundant
Initial transcript without processing is known as
48. Prokaryotic only. Elongates leading strand by adding deoxynucleotides to the 3prime end. Elongates laggin strand. 3 prime to 5 prime exonuclease activity
Cilia structure
frame shift
nucleosid
DNA pol III
49. You glyucosolate hte pro - alpha chain lysine resudens and form procollagen (triple helix of alpha chains)
DNA pol I
Tetracyclines
Cilia structure
Glycosolation
50. Retrograde to microtubules
Xeroderma pigmentosum
Elastin is broken down by
dyenin
Double Strand DNA repair