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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Each codon specifies only 1 amino acid
unambiguous
microtubule
Vincristine/Vinblastine
Excocytosis of collagen
2. One codon AUG
methionine is only encoded by
6MP
What does the hydroxylation of proline and lysine require
promoter
3. GTP
tRNA gripping and going places
Higher the cholesterol or long saturated fatty acid content
DNA pol I
Alports syndrome
4. ATP
Prokaryote RNA pol
Type IV collagen is an important structural component of...
Aminoacylt - tRNA synthetase
tRNA activation
5. Remain in G0 regenerate from stem cells
Methotrexate
tRNA
Permanent cells
Loading tRNA on to ribosome energy requirement
6. A site - incoming aminoacyl tRNA - Psite accomodates growing Peptide - E site holds EmplytRNA as it exits
Alternate splicing
alpha amintin
Going APE
Elastin is broken down by
7. Substituting a purine for a pyrimdine or vice versa
transversion
Mebendazole/thiabendazole
Cell cycle order
transition
8. Blocks denovo purine synthesis
Immunohistochemical stains vimentin
6MP
5FU
Proofreading function in eukaryotic RNA
9. Change resulting in misreading of all nucleotides downstream - usually resulting in a truncated non functional protien
Termination
Which end of a growing DNA strand is the target
Aminoacylt - tRNA synthetase
frame shift
10. Strethchy protein within lungs - large artiers - elastic liaments - vocal cords - ligamenta flava)
Elastin
helicase
Elongation
Hereditary non polyposis colorectal cancer
11. Methyl THYmine has a meTHYl
Thymine has a
commaless - non - overlapping
Free ribosomes
Nucleotide excision repair
12. VItamin C
Common amino acids in elastin
Free ribosomes
What does the hydroxylation of proline and lysine require
Alternate splicing
13. G1 - S - G2 - Mitosis
Cell cycle order
Which end of a growing DNA strand is the target
6MP
Nucleotide excision repair
14. Inhibit formation of the initation complex and cause misreading of mRNA
Termination
Aminoglycosides
Chediak Higashi syndrome
Which end of the tRNA is the amino acid bound to?
15. Bind 50S blocking translocation
Macrolides
Non homologous end joining
Neurofilaments
Guanine has a
16. Anit helminth - act on microtubules
White codon is at the 3 prime end of a tRNA
Promoter mutation
helicase
Mebendazole/thiabendazole
17. Greater melting temperature lower fluidity
Example of permanent cells
Non homologous end joining
Higher the cholesterol or long saturated fatty acid content
Free ribosomes
18. HS1 - HSB - H2 - H4
missense mutation
Post - translational modifications
Deamination of cytosine makes
histone octamer names
19. Ketone
Guanine has a
transversion
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
Axonemal dyenin
20. Close to - far from or even within (in an intron) the gene whose expression it regulates
Vincristine/Vinblastine
Cyclin - CDK
Enhancers and silencer may be located_____
GFAP
21. Attachment of ubiquitin to defective proteinds to tag them for breakdown
Pyrimidines
Griseofulvin
Proteosomal degradation
DNA pol III
22. Site where RNA polymerase and multiple other transciption factors bind to DNA upstream from gene locus (AT rich upstream sequence with TATA and CAAT boxes)
Chloramphenicol
Step Three of RNA processing
promoter
Smooth ER
23. Microtubule polymerization defect resulting in lowered phagocytosis. results in recurrent pyogenic infections - partial albinism and peripheral neuropathy
C- G bond
Oubain
Silencer
Chediak Higashi syndrome
24. H1
Elastin is broken down by
dyenin
Cilia structure
The only histone not on the core
25. Stretch of DNA that alters gene expression by binding transcription factors
Digoxin (cardiac glycosides)
Enhancer
Stable (quiescent)
Aminoacylt - tRNA synthetase
26. Different exons can be combined to make nique protiens in different times
Alternate splicing
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
mRNA start codons
silent mutation
27. Inhbits RNA pol II (found in death cap mushrooms)
Where do introns and exons stay
hydroxyurea
alpha amintin
Paclitaxil
28. AD and AR- associated iwth joint dislocation - berry aneurysms - organ rupture
Which end of a growing DNA strand is the target
Initial transcript without processing is known as
Associations of Ehlers Danlos
Deamination of cytosine makes
29. Same aa often base change in 3rd position of codon
silent mutation
Elastin is broken down by
Sodium K ATPase
transition
30. Immotile cilia due to a dyenin arm defect. Results in male nad female inferticility (sperm immotile) - bronchiectasis - and recurrent sinusisits - associated with situs inversus
Kartageners syndrome
Deamination of cytosine makes
Total energy expenditure requirement for translocation
nucleotide
31. Even 40S 60S =80S
DNA pol I
Fluoroquinolones
Eukaroytes
Protein synthesis initiation
32. 1) primary transcript combines with snRNPs and other proteins to form spliceosome 2) lariat shaped intermediate is generated 3) Lariat is removed and released to precisely join 2 exons
Protein synthesis is in which direction
Example of permanent cells
Methotrexate
Steps in splicing
33. Inhibits ribonucleotide reductase
Eukaroytes
trimethoprim
hydroxyurea
Euchromatin
34. The 3 prime end
Which end of the tRNA is the amino acid bound to?
Eukaroytes
origin of replication
Thymine has a
35. Less condensed - transciptionally active=eu truly transcobed
trimethoprim
commaless - non - overlapping
nucleosid
Euchromatin
36. Asymmetric fluid bilayer - contains - cholesterol - phospholipids - sphingoplipids - glycolipids - and protiends
mRNA stop codons
Collagen
Plasma membrane composition
Purines
37. You glyucosolate hte pro - alpha chain lysine resudens and form procollagen (triple helix of alpha chains)
Glycosolation
transversion
Oubain
microtubule
38. Non homologous end joining
step two of RNA processing
Double Strand DNA repair
transversion
Tumor Suppressors
39. Anti breast cancer - acts on mts
Oubain
polyadenylation does/does not require a template
Excocytosis of collagen
Paclitaxil
40. 5 prime to 3 prime
Elastase is inhibited by
mRNA is syntehsized in which direction?
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
Base excision repair
41. Promoter - enhancer - promoter - TATA- transcription initiation site - coding region (including exons and introns) and then the AATAAA
Functional organization of the gene
What type of collagen is most affected in Ehlers Danlos
mRNA start codons
Deamination of cytosine makes
42. DNA And RNA synthesized in the 5-3 direction
chromatin structure
DNA/RNA/Protein syntesis direction
Kartageners syndrome
Permanent cells
43. Bm - kidney - ears and eyes
Type IV collagen is an important structural component of...
RNA processing in eukaryotes occurs
Replication fork
Smooth ER
44. Codes for formyl methionine (f - Met)
Heterochromatin
Prokaryote RNA pol
Order of mitosis
AUG codes For what in prokaryotes
45. AUG inAUGurates protein synthesis
mRNA start codons
Which end of a growing DNA strand is the target
Mebendazole/thiabendazole
AUG codes For what in prokaryotes
46. The N to C
Protein synthesis is in which direction
Eukaroytes
trimethoprim
Immunohistochemical stains vimentin
47. Introns stay In the nucleus whereas EXons EXit and are EXpressed
Where do introns and exons stay
Associations of Ehlers Danlos
transition
single stranded binding proteinds
48. The 5prime end (energy for the bond)
Mebendazole/thiabendazole
CDKs
silent mutation
Which end of the nucleotide has the triphosphate
49. Inhibits 50S peptidyl transferase
Purines
DNA pol III
alpha amintin
Chloramphenicol
50. Regulatory proteins that control cell cycle events; phase specific; activated CDKs
Base excision repair
Cyclins
Methotrexate
Covalent alterations