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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Completed protein is released from ribosme through simple hydrolosis and dissociates
Vincristine/Vinblastine
methionine is only encoded by
Termination
Protein synthesis initiation
2. Regulatory proteins that control cell cycle events; phase specific; activated CDKs
Cyclins
Griseofulvin
DNA ligase
Protein synthesis initiation
3. 3 sodium out for 2 potassium in (nout - kin)takes 1 atp and the machine is phosphorylated during the machine cycle
promoter
Sodium K ATPase
tRNA Structure
GFAP
4. 75-90 nucleotides - 2ary structure cloverleaf form anticodon end is opposite 3 prime aminoacyl end
Purines
Pyrimidines
tRNA Structure
helicase
5. Activated by GTP hydrolosis initiation factors help assembel the 40 S ribosomal subunites with the initiatior tRNA and are released whent he mRNA and the ribosomal subunit assemple with the complex
Paclitaxil
Protein synthesis initiation
What ties teh nucleosome together
Thymine has a
6. Base+ribose+phosphate linked by a phosphodiester bond
Termination
Cyclins
Gag on pure gold
nucleotide
7. Trimming removal of n or c terminal propeptides from zymogens to generate mature proteinds
hydroxyurea
Hereditary non polyposis colorectal cancer
Sodium K ATPase
Post - translational modifications
8. Inhibits ribonucleotide reductase
hydroxyurea
Step one of RNA processing
C- G bond
In eukaryotes the starting amino acid is...
9. Has enough energy to created the peptide bond
the tRNA- amino acid bond
AUG codes For what in prokaryotes
Going APE
polyadenylation does/does not require a template
10. Particular sequnece in genomre where DNA replication begins. May be single (prokaryotes) or multiple (eukaryotes)
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
origin of replication
Functional organization of the gene
Digoxin (cardiac glycosides)
11. Blocks denovo purine synthesis
6MP
Molecular motor protiesn
Sodium K ATPase
Functional organization of the gene
12. Specific endonucleases release the oligonucleotide containing damaged bases. DNA polymerase and logase fill and resealt eh gap
Excocytosis of collagen
Nucleotide excision repair
alpha amintin
Guanine has a
13. Proline - glycine
Common amino acids in elastin
Vincristine/Vinblastine
Tetracyclines
Hydroxylation of which amino acids are attached to Glycine to form collagen
14. Unattached to any membrane; site of cytosolic and organeller prtoeins
Free ribosomes
Purines
What ties teh nucleosome together
Fluoroquinolones
15. 1) primary transcript combines with snRNPs and other proteins to form spliceosome 2) lariat shaped intermediate is generated 3) Lariat is removed and released to precisely join 2 exons
Example of permanent cells
Steps in splicing
mRNA is syntehsized in which direction?
nonsense
16. Microtubule polymerization defect resulting in lowered phagocytosis. results in recurrent pyogenic infections - partial albinism and peripheral neuropathy
Chediak Higashi syndrome
Replication fork
tRNA
desmin
17. Prevents stranges from reannealing
Macrolides
kinesin
Cell cycle
single stranded binding proteinds
18. ATP ase that links peripheral 9 doublets and causes bending of cilium by differential sliding of doublets
Order of mitosis
Axonemal dyenin
Thymine has a
Double Strand DNA repair
19. Enter G1 from G0 when stimulated Hepatocytes/lymphocytes
Stable (quiescent)
CDKs
nucleotide
Base excision repair
20. Inhibits thymidylate synthase down thymine
nucleotide
Alports syndrome
5FU
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
21. Inhibits by binding to the potassium side
Common amino acids in elastin
Purines
universal
Oubain
22. AUG inAUGurates protein synthesis
Which end of a growing DNA strand is the target
Double Strand DNA repair
A- T
mRNA start codons
23. Brings together 2 ends of DNA fragments no requirement for homology
commaless - non - overlapping
Non homologous end joining
cytokeratin
chromatin structure
24. 4 high enrgy bonds
Total energy expenditure requirement for translocation
dyenin
Gag on pure gold
transition
25. Greater melting temperature lower fluidity
Higher the cholesterol or long saturated fatty acid content
chromatin structure
Which end of the nucleotide has the triphosphate
Kartageners syndrome
26. Site where negative regulators bind
Elastin is broken down by
promoter
Silencer
Elastase is inhibited by
27. Substituting a pyramidine for a pyrimadine
pyrimadines
transition
White codon is at the 3 prime end of a tRNA
DNA/RNA/Protein syntesis direction
28. (A - G) 2 rings Pure As Gold
What ties teh nucleosome together
Gag on pure gold
Purines
pyrimadines
29. 1P (blocked by tetracycline)
tRNA aminoacylation
Loading tRNA on to ribosome energy requirement
degenerate or redundant
Silencer
30. Hydroxy proline and hydroxylysine
DNA topoisomerases
Hydroxylation of which amino acids are attached to Glycine to form collagen
Which end of a growing DNA strand is the target
Mismatch repair
31. Introns stay In the nucleus whereas EXons EXit and are EXpressed
Alternate splicing
Which is the most and least abundant type of RNA
Where do introns and exons stay
histone octamer names
32. Site of dteroid synthesis and detoxification of druigs and poisons (liver hepatocytes and steroid horomore adrenal cortex)
Smooth ER
Permanent cells
Tropocollagen cross links between_____ to form____
kinesin
33. 1 RNA polymerase (multisubunite complex) makes all 3 kinds of RNA
Prokaryote RNA pol
degenerate or redundant
Which end of the tRNA is the amino acid bound to?
missense mutation
34. Same aa often base change in 3rd position of codon
Elastase is inhibited by
missense mutation
silent mutation
Where do introns and exons stay
35. Connective tissue
commaless - non - overlapping
Immunohistochemical stains vimentin
Which end of the nucleotide has the triphosphate
Excocytosis of collagen
36. The 5prime end (energy for the bond)
Order of mitosis
Mismatch repair
polyadenylation does/does not require a template
Which end of the nucleotide has the triphosphate
37. Intervening noncoding segments of DNA
Permanent cells
Introns
Prokaryote RNA pol
Chloramphenicol
38. Ketone
CDKs
Aminoacylt - tRNA synthetase
Guanine has a
tRNA activation
39. Inhibits bacterials dihydrofolate reducatese down thymine
trimethoprim
Elastin is broken down by
Step one of RNA processing
promoter
40. Prokaryotic only. Degrades RNA primer and fills in the gap with DNA (5 prime to 3 prime exonuclease)
Nucleotide excision repair
Elongation
nonsense
DNA pol I
41. Genetic bone disorder (brittle bone disease) type 1 colalgen - fractures (during birth) 2) Blue sclerae 3) hearing loss 4) dental imperfections 1:10000 may be confused with child abuse
Osteogenesis Imperfecta
A- T
unambiguous
Prokaryote RNA pol
42. Methyl THYmine has a meTHYl
GFAP
Hereditary non polyposis colorectal cancer
Thymine has a
microtubule
43. UGA - UAG - UAA
degenerate or redundant
Tumor Suppressors
mRNA is syntehsized in which direction?
mRNA stop codons
44. In the nucleus after transcitpion and only processed RNA is transporte out of the nucleus
RNA processing in eukaryotes occurs
Ehlers Danlos
capped and tail transcript is called
transition
45. Cleave terminal regions of procollagen to transform into insoluable tropocolagen
Outside the cell what processing must be done in procolalgen
Step one of RNA processing
Which end of the nucleotide has the triphosphate
methionine is only encoded by
46. Rampant - Massive - TIny rRNA is most common - then mRNA and then tRNA
tRNA activation
Which is the most and least abundant type of RNA
Cilia structure
C- G bond
47. G1 - S - G2 - Mitosis
Excocytosis of collagen
A- T
Covalent alterations
Cell cycle order
48. Checkpoints control transition between phases of cell cycle. regulated by cyclins - CDKs and tumor suppressors. Mitosis (shortest phse)
Silencer
Cell cycle
Sodium K ATPase
Which end of the nucleotide has the triphosphate
49. MRNA
commaless - non - overlapping
tRNA gripping and going places
capped and tail transcript is called
Stable (quiescent)
50. Lysine/hydroxylysine and combines to form collagen
Silencer
silent mutation
Hereditary non polyposis colorectal cancer
Tropocollagen cross links between_____ to form____