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First Aid: Biochemistry Molecular

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Non homologous end joining






2. Substituting a pyramidine for a pyrimadine






3. Neurons - skeletal - and cardiac muscle - RBCs






4. Stretch of DNA that alters gene expression by binding transcription factors






5. Anti breast cancer - acts on mts






6. Cleave terminal regions of procollagen to transform into insoluable tropocolagen






7. Read froma fixed starting point as a continous sequenecs of bases






8. P53 and RB normally inhibit g1 to S progression






9. Substituting a purine for a pyrimdine or vice versa






10. RNA polymerase I makes rRNA - RNA pol II makes mRNA - RNA pol III makes tRNA






11. Rampant - Massive - TIny rRNA is most common - then mRNA and then tRNA






12. Cyclin depndent kinases; consituative and inactive






13. Strethchy protein within lungs - large artiers - elastic liaments - vocal cords - ligamenta flava)






14. Hydroxy proline and hydroxylysine






15. Changed aaconservative - new aa is similar in chemical structure






16. Never go to Go divide rapidly with short G1 bone marrow - gut epithelium - skin - hair follicles






17. Antigout - acts on mts






18. Close to - far from or even within (in an intron) the gene whose expression it regulates






19. Alpha 1 antitrypisn






20. Responsible for the accuracy of amino acid selection






21. Base+ribose+phosphate linked by a phosphodiester bond






22. Genetic bone disorder (brittle bone disease) type 1 colalgen - fractures (during birth) 2) Blue sclerae 3) hearing loss 4) dental imperfections 1:10000 may be confused with child abuse






23. Elastase






24. Promoter - enhancer - promoter - TATA- transcription initiation site - coding region (including exons and introns) and then the AATAAA






25. Aminoacyl - tRNA binds to A site 2) peptidyltransferase catalyzes peptide bond formation transfers growing polypeptie to amino acid in A site 3) ribosome advances 3 nucleotides toward the 3 prime end of RNA moving peptiydyl RNA to P site






26. Remain in G0 regenerate from stem cells






27. 2 H bonds greater GC content greater melting point






28. Bind 50S blocking translocation






29. Does not






30. 1 RNA polymerase (multisubunite complex) makes all 3 kinds of RNA






31. Completed protein is released from ribosme through simple hydrolosis and dissociates






32. Activated by GTP hydrolosis initiation factors help assembel the 40 S ribosomal subunites with the initiatior tRNA and are released whent he mRNA and the ribosomal subunit assemple with the complex






33. Anit helminth - act on microtubules






34. Made from orogate precuror with PRPP added later






35. Each codon specifies only 1 amino acid






36. Y shaped region along DNA template where leading and lagging strands are syntehsized






37. Intervening noncoding segments of DNA






38. Scrutinizes aa before and after it binds to tRNA. If incorrect bond is hydrolyzed.






39. 5 prime to 3 prime






40. 4 high enrgy bonds






41. G1 - S - G2 - Mitosis






42. Accurate base pairing is required only in the first 2 nucleotide positions of an mRNA so codons differing ht e3rd wobble psoition may code for the same tRNA/amino acid code






43. H1 string






44. A site - incoming aminoacyl tRNA - Psite accomodates growing Peptide - E site holds EmplytRNA as it exits






45. 3 sodium out for 2 potassium in (nout - kin)takes 1 atp and the machine is phosphorylated during the machine cycle






46. Ribonucleotide reductase






47. ATP






48. Change resulting in misreading of all nucleotides downstream - usually resulting in a truncated non functional protien






49. Immotile cilia due to a dyenin arm defect. Results in male nad female inferticility (sperm immotile) - bronchiectasis - and recurrent sinusisits - associated with situs inversus






50. Nucleotide excision repair - Base Excision repair - Mismath repair