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First Aid: Biochemistry Molecular

Instructions:
  • Answer 50 questions in 15 minutes.
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  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Inhibits 50S peptidyl transferase






2. Prophas - metaphase - anaphase telophase






3. 3 sodium out for 2 potassium in (nout - kin)takes 1 atp and the machine is phosphorylated during the machine cycle






4. Made from IMP precursor






5. Non homologous end joining






6. Neurons






7. Microtubule polymerization defect resulting in lowered phagocytosis. results in recurrent pyogenic infections - partial albinism and peripheral neuropathy






8. Neurons - skeletal - and cardiac muscle - RBCs






9. Elastase






10. Three amino acids necessary for purine synthesis= glutamine - aspartate and glycine






11. Exocytose procollagen into extracellylar sace






12. Tansport cellular cargo toward opposite ends of microtubule tracks






13. Read froma fixed starting point as a continous sequenecs of bases






14. Substituting a purine for a pyrimdine or vice versa






15. Commonly results in dramatic decrease in amount of gene transcribed






16. Base+ribose+phosphate linked by a phosphodiester bond






17. Greater melting temperature lower fluidity






18. CUT 1 ring Cut the Py






19. Uracil






20. Site of secretory protiens (mucus secreting goblet cells and antibody secreting cells)






21. 3 H bonds






22. Cleave terminal regions of procollagen to transform into insoluable tropocolagen






23. Remain in G0 regenerate from stem cells






24. Responsible for the accuracy of amino acid selection






25. Changed aaconservative - new aa is similar in chemical structure






26. Methionine - which may be removed before translation is completed






27. One codon AUG






28. No proofreading function but can initiate chains. RNA poymerase II opens DNA at promoter site






29. Change resulting in misreading of all nucleotides downstream - usually resulting in a truncated non functional protien






30. Negatively charged DNA loops twice around histone octamers create a nucloesome bead.






31. Prokaryotic only. Elongates leading strand by adding deoxynucleotides to the 3prime end. Elongates laggin strand. 3 prime to 5 prime exonuclease activity






32. Contain the actual genetic information coding for protein






33. Splicing out of introns






34. Genetic bone disorder (brittle bone disease) type 1 colalgen - fractures (during birth) 2) Blue sclerae 3) hearing loss 4) dental imperfections 1:10000 may be confused with child abuse






35. Aminoacyl - tRNA binds to A site 2) peptidyltransferase catalyzes peptide bond formation transfers growing polypeptie to amino acid in A site 3) ribosome advances 3 nucleotides toward the 3 prime end of RNA moving peptiydyl RNA to P site






36. Site where RNA polymerase and multiple other transciption factors bind to DNA upstream from gene locus (AT rich upstream sequence with TATA and CAAT boxes)






37. G1 - S - G2 - Mitosis






38. Scrutinizes aa before and after it binds to tRNA. If incorrect bond is hydrolyzed.






39. Anti breast cancer - acts on mts






40. Ribonucleotide reductase






41. Hn RNA






42. Muscle






43. Poly adenylation






44. More than 1 codon may code for the same amino acid






45. Specific endonucleases release the oligonucleotide containing damaged bases. DNA polymerase and logase fill and resealt eh gap






46. Proline - glycine






47. 2 H bonds greater GC content greater melting point






48. Particular sequnece in genomre where DNA replication begins. May be single (prokaryotes) or multiple (eukaryotes)






49. Be So Totatally Cool Read Books (bOne - CarTWOlage - Threeticular - Type IV under the floor)






50. The N to C