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First Aid: Biochemistry Molecular

Instructions:
  • Answer 50 questions in 15 minutes.
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  • Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Site of dteroid synthesis and detoxification of druigs and poisons (liver hepatocytes and steroid horomore adrenal cortex)






2. Makes an RNA primer on which DNA polymerase II can initiate replication






3. Inhibits by binding to the potassium side






4. Inhibits ribonucleotide reductase






5. Rampant - Massive - TIny rRNA is most common - then mRNA and then tRNA






6. Epithelial cells






7. 4 high enrgy bonds






8. ATP ase that links peripheral 9 doublets and causes bending of cilium by differential sliding of doublets






9. Commonly results in dramatic decrease in amount of gene transcribed






10. Inhibits 50S peptidyl transferase






11. Antifungal - act on microtubules






12. Bind 30S subunit preventing attachment of aminoacyl - tRNA






13. Inhibits dihydrofolate reductase down thymine






14. Lysine/hydroxylysine and combines to form collagen






15. Anti breast cancer - acts on mts






16. Prokaryotic only. Elongates leading strand by adding deoxynucleotides to the 3prime end. Elongates laggin strand. 3 prime to 5 prime exonuclease activity






17. Specific glycosylases recognize and remove damaged bases - AP endonuclease cuts DNA at pyrimidne site - empty sugar is removed and the gap is filled and resealed






18. Asymmetric fluid bilayer - contains - cholesterol - phospholipids - sphingoplipids - glycolipids - and protiends






19. Made from IMP precursor






20. 75-90 nucleotides - 2ary structure cloverleaf form anticodon end is opposite 3 prime aminoacyl end






21. H1






22. Poly adenylation






23. Antigout - acts on mts






24. AUG inAUGurates protein synthesis






25. 1) primary transcript combines with snRNPs and other proteins to form spliceosome 2) lariat shaped intermediate is generated 3) Lariat is removed and released to precisely join 2 exons






26. Substituting a pyramidine for a pyrimadine






27. Blocks denovo purine synthesis






28. Type III






29. Splicing out of introns






30. ATP- AMP (2 phosphoanhydride bonds)






31. Prophas - metaphase - anaphase telophase






32. Capping on 5 prime end (7 methylguanosine) -






33. One codon AUG






34. Enter G1 from G0 when stimulated Hepatocytes/lymphocytes






35. Responsible for the accuracy of amino acid selection






36. HS1 - HSB - H2 - H4






37. Regulatory proteins that control cell cycle events; phase specific; activated CDKs






38. Same aa often base change in 3rd position of codon






39. Elastase






40. Immotile cilia due to a dyenin arm defect. Results in male nad female inferticility (sperm immotile) - bronchiectasis - and recurrent sinusisits - associated with situs inversus






41. A site - incoming aminoacyl tRNA - Psite accomodates growing Peptide - E site holds EmplytRNA as it exits






42. P53 and RB normally inhibit g1 to S progression






43. RNA polymerase I makes rRNA - RNA pol II makes mRNA - RNA pol III makes tRNA






44. Attachment of ubiquitin to defective proteinds to tag them for breakdown






45. UGA - UAG - UAA






46. 2 H bonds greater GC content greater melting point






47. Each codon specifies only 1 amino acid






48. 1P (blocked by tetracycline)






49. Does not






50. Strethchy protein within lungs - large artiers - elastic liaments - vocal cords - ligamenta flava)






Can you answer 50 questions in 15 minutes?



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