SUBJECTS
|
BROWSE
|
CAREER CENTER
|
POPULAR
|
JOIN
|
LOGIN
Business Skills
|
Soft Skills
|
Basic Literacy
|
Certifications
About
|
Help
|
Privacy
|
Terms
|
Email
Search
Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Stretch of DNA that alters gene expression by binding transcription factors
GFAP
Termination
Enhancer
tRNA activation
2. H1
Excocytosis of collagen
Tropocollagen cross links between_____ to form____
The only histone not on the core
GFAP
3. Responsible for the accuracy of amino acid selection
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
Axonemal dyenin
desmin
Collagen
4. Commonly results in dramatic decrease in amount of gene transcribed
Initial transcript without processing is known as
Which is the most and least abundant type of RNA
Promoter mutation
Associations of Ehlers Danlos
5. Remain in G0 regenerate from stem cells
Elongation
dyenin
Permanent cells
Where do introns and exons stay
6. Site where RNA polymerase and multiple other transciption factors bind to DNA upstream from gene locus (AT rich upstream sequence with TATA and CAAT boxes)
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
promoter
Type IV collagen is an important structural component of...
Cholchicine
7. Cilia - glagella - mitotic spindle - neurons - centrioles
Elongation
6MP
microtubule
actin and myosin
8. Site of dteroid synthesis and detoxification of druigs and poisons (liver hepatocytes and steroid horomore adrenal cortex)
Smooth ER
Heterochromatin
Clindamycin
5FU
9. Promoter - enhancer - promoter - TATA- transcription initiation site - coding region (including exons and introns) and then the AATAAA
methionine is only encoded by
Which end of the tRNA is the amino acid bound to?
Functional organization of the gene
Glycosolation
10. 75-90 nucleotides - 2ary structure cloverleaf form anticodon end is opposite 3 prime aminoacyl end
Cell cycle
Type IV collagen is an important structural component of...
tRNA Structure
Elastin
11. Cyclin depndent kinases; consituative and inactive
degenerate or redundant
CDKs
Going APE
actin and myosin
12. Microtubule polymerization defect resulting in lowered phagocytosis. results in recurrent pyogenic infections - partial albinism and peripheral neuropathy
Example of permanent cells
origin of replication
silent mutation
Chediak Higashi syndrome
13. Mutation in nucleotide excision repair Dry skin with melanoma and other cancers
Cyclins
Mebendazole/thiabendazole
Xeroderma pigmentosum
Alports syndrome
14. The 3 prime end
pyrimadines
Proteosomal degradation
Which end of the tRNA is the amino acid bound to?
What does the hydroxylation of proline and lysine require
15. Never go to Go divide rapidly with short G1 bone marrow - gut epithelium - skin - hair follicles
mRNA stop codons
Nucleotide excision repair
Aminoacylt - tRNA synthetase
Labile
16. You glyucosolate hte pro - alpha chain lysine resudens and form procollagen (triple helix of alpha chains)
Which end of a growing DNA strand is the target
Glycosolation
desmin
Molecular motor protiesn
17. Methionine - which may be removed before translation is completed
In eukaryotes the starting amino acid is...
Example of permanent cells
Purines
Smooth ER
18. Immotile cilia due to a dyenin arm defect. Results in male nad female inferticility (sperm immotile) - bronchiectasis - and recurrent sinusisits - associated with situs inversus
Kartageners syndrome
Exons
Purines
single stranded binding proteinds
19. Phosphorylation - glycosloation - hyderoxylation
Cholchicine
silent mutation
Covalent alterations
Prokaryote RNA pol
20. Lysine/hydroxylysine and combines to form collagen
mRNA stop codons
Replication fork
AUG codes For what in prokaryotes
Tropocollagen cross links between_____ to form____
21. The 5prime end (energy for the bond)
Cyclins
Chediak Higashi syndrome
Which end of the nucleotide has the triphosphate
Functional organization of the gene
22. Anterograde to microtubule
kinesin
Elongation
mRNA stop codons
The only histone not on the core
23. Different exons can be combined to make nique protiens in different times
Introns
Alternate splicing
Single Strand DNA Repair types
Cyclins
24. The 3 prime hydroxyl of the nascent chain is the target
Which end of a growing DNA strand is the target
trimethoprim
cytokeratin
Permanent cells
25. Faulty collagen synthesis causing 1) hyperextensible skin 2) tendency to bleed 3) hypermobile joints
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
silent mutation
Ehlers Danlos
Elastase is inhibited by
26. DNA And RNA synthesized in the 5-3 direction
Euchromatin
The only histone not on the core
Ehlers Danlos
DNA/RNA/Protein syntesis direction
27. Inhbits RNA pol II (found in death cap mushrooms)
alpha amintin
Where do introns and exons stay
Chloramphenicol
capped and tail transcript is called
28. ATP
tRNA activation
Base excision repair
Immunohistochemical stains vimentin
commaless - non - overlapping
29. 3 H bonds
C- G bond
Chediak Higashi syndrome
Clindamycin
kinesin
30. Inhibits 50S peptidyl transferase
Outside the cell what processing must be done in procolalgen
Chloramphenicol
What ties teh nucleosome together
Mismatch repair
31. Vimentin - desmin - cytockeratin - glial fibrillary acid proteins - neurofilaments
Protein synthesis is in which direction
intermediate filaments
degenerate or redundant
microtubule
32. Codes for formyl methionine (f - Met)
AUG codes For what in prokaryotes
Pyrimidines
Griseofulvin
single stranded binding proteinds
33. Introns stay In the nucleus whereas EXons EXit and are EXpressed
Euchromatin
Where do introns and exons stay
5FU
Exons
34. Methyl THYmine has a meTHYl
Step Three of RNA processing
Which end of the nucleotide has the triphosphate
Primase
Thymine has a
35. Checkpoints control transition between phases of cell cycle. regulated by cyclins - CDKs and tumor suppressors. Mitosis (shortest phse)
the tRNA- amino acid bond
Cell cycle
Macrolides
Immunohistochemical stains vimentin
36. 1) primary transcript combines with snRNPs and other proteins to form spliceosome 2) lariat shaped intermediate is generated 3) Lariat is removed and released to precisely join 2 exons
Going APE
Type IV collagen is an important structural component of...
What type of collagen is most affected in Ehlers Danlos
Steps in splicing
37. VItamin C
What does the hydroxylation of proline and lysine require
Xeroderma pigmentosum
Cilia structure
Axonemal dyenin
38. Change resulting in misreading of all nucleotides downstream - usually resulting in a truncated non functional protien
desmin
Alternate splicing
frame shift
Xeroderma pigmentosum
39. Inhibits by binding to the potassium side
Oubain
Functional organization of the gene
pyrimadines
degenerate or redundant
40. Change resulting in early stop codon
What type of collagen is most affected in Ehlers Danlos
nonsense
microtubule
commaless - non - overlapping
41. Bm - kidney - ears and eyes
unambiguous
Macrolides
Axonemal dyenin
Type IV collagen is an important structural component of...
42. Connective tissue
Aminoglycosides
Kartageners syndrome
Immunohistochemical stains vimentin
Euchromatin
43. HS1 - HSB - H2 - H4
histone octamer names
Stable (quiescent)
promoter
Eukaroytes
44. Anti breast cancer - acts on mts
single stranded binding proteinds
Paclitaxil
AUG codes For what in prokaryotes
commaless - non - overlapping
45. Unwinds DNA template at replication fork
single stranded binding proteinds
Which is the most and least abundant type of RNA
AUG codes For what in prokaryotes
helicase
46. Xlinked recessive IV collagen bm - kidney - ear and eye -- nephritis and defness ocular disturbances
mRNA start codons
Enhancers and silencer may be located_____
Alports syndrome
C- G bond
47. More than 1 codon may code for the same amino acid
The only histone not on the core
degenerate or redundant
tRNA
Aminoglycosides
48. Seals
Xeroderma pigmentosum
DNA ligase
mRNA is syntehsized in which direction?
Proofreading function in eukaryotic RNA
49. Y shaped region along DNA template where leading and lagging strands are syntehsized
Exons
Free ribosomes
Protein synthesis is in which direction
Replication fork
50. Be So Totatally Cool Read Books (bOne - CarTWOlage - Threeticular - Type IV under the floor)
Griseofulvin
tRNA
Collagen
unambiguous