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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Be So Totatally Cool Read Books (bOne - CarTWOlage - Threeticular - Type IV under the floor)
dyenin
Thymine has a
Collagen
DNA/RNA/Protein syntesis direction
2. Inhibit formation of the initation complex and cause misreading of mRNA
Mebendazole/thiabendazole
Neurofilaments
Methotrexate
Aminoglycosides
3. The 5prime end (energy for the bond)
Which end of the nucleotide has the triphosphate
Prokaryote RNA pol
Euchromatin
Collagedn synthesis where?
4. Cylindrical structure composed of helical array of plymerized dimers of alpha and beta tubulin - flagella - cilia - mitotic spindle - grows slowly collapses quickly
Alternate splicing
Guanine has a
microtubule
Macrolides
5. Hydroxy proline and hydroxylysine
Hydroxylation of which amino acids are attached to Glycine to form collagen
Initial transcript without processing is known as
Non homologous end joining
Alports syndrome
6. Capping on 5 prime end (7 methylguanosine) -
Hydroxylation of which amino acids are attached to Glycine to form collagen
Step one of RNA processing
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
silent mutation
7. Makes an RNA primer on which DNA polymerase II can initiate replication
Primase
DNA ligase
Elongation
tRNA gripping and going places
8. Specific glycosylases recognize and remove damaged bases - AP endonuclease cuts DNA at pyrimidne site - empty sugar is removed and the gap is filled and resealed
nucleotide
Elastin
tRNA aminoacylation
Base excision repair
9. Tansport cellular cargo toward opposite ends of microtubule tracks
Molecular motor protiesn
commaless - non - overlapping
origin of replication
Cyclin - CDK
10. Neurons
Neurofilaments
Immunohistochemical stains vimentin
Proofreading function in eukaryotic RNA
Exons
11. Inhibits 50S peptidyl transferase
Chloramphenicol
microtubule
Which end of the tRNA is the amino acid bound to?
GFAP
12. Contain the actual genetic information coding for protein
Excocytosis of collagen
Exons
Elastin
Cell cycle order
13. Changed aaconservative - new aa is similar in chemical structure
Fluoroquinolones
Hydroxylation of which amino acids are attached to Glycine to form collagen
microtubule
missense mutation
14. Has enough energy to created the peptide bond
the tRNA- amino acid bond
capped and tail transcript is called
cytokeratin
Kartageners syndrome
15. Intervening noncoding segments of DNA
commaless - non - overlapping
Introns
missense mutation
tRNA activation
16. Vimentin - desmin - cytockeratin - glial fibrillary acid proteins - neurofilaments
Double Strand DNA repair
The only histone not on the core
Purines
intermediate filaments
17. Connective tissue
nucleotide
the tRNA- amino acid bond
Gag on pure gold
Immunohistochemical stains vimentin
18. Type III
Osteogenesis Imperfecta
What type of collagen is most affected in Ehlers Danlos
Aminoacylt - tRNA synthetase
Step one of RNA processing
19. Introns stay In the nucleus whereas EXons EXit and are EXpressed
The only histone not on the core
Where do introns and exons stay
Exons
Order of mitosis
20. Anit helminth - act on microtubules
tRNA aminoacylation
Immunohistochemical stains vimentin
Cholchicine
Mebendazole/thiabendazole
21. Trimming removal of n or c terminal propeptides from zymogens to generate mature proteinds
Step one of RNA processing
Proteosomal degradation
Vincristine/Vinblastine
Post - translational modifications
22. Inhbits RNA pol II (found in death cap mushrooms)
hydroxyurea
DNA topoisomerases
alpha amintin
the tRNA- amino acid bond
23. 1) primary transcript combines with snRNPs and other proteins to form spliceosome 2) lariat shaped intermediate is generated 3) Lariat is removed and released to precisely join 2 exons
Outside the cell what processing must be done in procolalgen
Steps in splicing
What type of collagen is most affected in Ehlers Danlos
Elastin is broken down by
24. Neurons - skeletal - and cardiac muscle - RBCs
Higher the cholesterol or long saturated fatty acid content
Example of permanent cells
desmin
Elastin is broken down by
25. Site of secretory protiens (mucus secreting goblet cells and antibody secreting cells)
Digoxin (cardiac glycosides)
Hereditary non polyposis colorectal cancer
DNA pol I
Rough ER
26. Rampant - Massive - TIny rRNA is most common - then mRNA and then tRNA
Elongation
Sodium K ATPase
Which is the most and least abundant type of RNA
Heterochromatin
27. Close to - far from or even within (in an intron) the gene whose expression it regulates
Enhancers and silencer may be located_____
hydroxyurea
Stable (quiescent)
5FU
28. Inhibits the atpase which increases intracellular sodium which increases intracellular calcium increases cardiaccontractility
Digoxin (cardiac glycosides)
DNA/RNA/Protein syntesis direction
AUG codes For what in prokaryotes
the tRNA- amino acid bond
29. Inhibits bacterials dihydrofolate reducatese down thymine
Single Strand DNA Repair types
helicase
What type of collagen is most affected in Ehlers Danlos
trimethoprim
30. Particular sequnece in genomre where DNA replication begins. May be single (prokaryotes) or multiple (eukaryotes)
Elastin
Clindamycin
origin of replication
cytokeratin
31. Epithelial cells
Replication fork
Elastin
cytokeratin
Chloramphenicol
32. Promoter - enhancer - promoter - TATA- transcription initiation site - coding region (including exons and introns) and then the AATAAA
Which end of the nucleotide has the triphosphate
Primase
Functional organization of the gene
Macrolides
33. Ribonucleotide reductase
trimethoprim
nonsense
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
nucleotide
34. 4 high enrgy bonds
Total energy expenditure requirement for translocation
nonsense
Initial transcript without processing is known as
Alternate splicing
35. 9+2 arrangement of microtubules -
White codon is at the 3 prime end of a tRNA
Replication fork
cytokeratin
Cilia structure
36. Same aa often base change in 3rd position of codon
tRNA activation
silent mutation
DNA pol I
Initial transcript without processing is known as
37. Antigout - acts on mts
Exons
Cholchicine
Molecular motor protiesn
kinesin
38. Y shaped region along DNA template where leading and lagging strands are syntehsized
What type of collagen is most affected in Ehlers Danlos
Replication fork
Tropocollagen cross links between_____ to form____
RNA polymerases in eukaryotes
39. Change resulting in misreading of all nucleotides downstream - usually resulting in a truncated non functional protien
Base excision repair
CDKs
Collagedn synthesis where?
frame shift
40. Cleave terminal regions of procollagen to transform into insoluable tropocolagen
Covalent alterations
Outside the cell what processing must be done in procolalgen
Deamination of cytosine makes
silent mutation
41. 5 prime to 3 prime
mRNA is syntehsized in which direction?
Translocation
Macrolides
Xeroderma pigmentosum
42. No proofreading function but can initiate chains. RNA poymerase II opens DNA at promoter site
hydroxyurea
Pyrimidines
Proofreading function in eukaryotic RNA
microtubule
43. 2 H bonds greater GC content greater melting point
Primase
Functional organization of the gene
Initial transcript without processing is known as
A- T
44. Bind 30S subunit preventing attachment of aminoacyl - tRNA
Mebendazole/thiabendazole
Tetracyclines
Clindamycin
promoter
45. Cyclin depndent kinases; consituative and inactive
CDKs
degenerate or redundant
Glycosolation
Covalent alterations
46. GTP
Cholchicine
tRNA gripping and going places
Cell cycle
AUG codes For what in prokaryotes
47. Condensed - transciptionally inactive HC- Highly condensed
Methotrexate
Heterochromatin
C- G bond
Elongation
48. Odd 30S plus 50 S=70S
Stable (quiescent)
Permanent cells
commaless - non - overlapping
Prokaryotes
49. Create a nick in the helix to relieve supercoils created during replication
Prokaryote RNA pol
DNA topoisomerases
Free ribosomes
tRNA aminoacylation
50. Less condensed - transciptionally active=eu truly transcobed
Euchromatin
Chloramphenicol
Common amino acids in elastin
Protein synthesis is in which direction