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First Aid: Biochemistry Molecular

Subjects : health-sciences, first-aid

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Type III
Hydroxylation of which amino acids are attached to Glycine to form collagen
Nucleotide excision repair
Non homologous end joining
What type of collagen is most affected in Ehlers Danlos

2. Makes an RNA primer on which DNA polymerase II can initiate replication
RNA polymerases in eukaryotes
Cholchicine
Example of permanent cells
Primase

3. Inhibits ribonucleotide reductase
cytokeratin
kinesin
hydroxyurea
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by

4. 3 sodium out for 2 potassium in (nout - kin)takes 1 atp and the machine is phosphorylated during the machine cycle
Xeroderma pigmentosum
Sodium K ATPase
Digoxin (cardiac glycosides)
Elastin is broken down by

5. Immotile cilia due to a dyenin arm defect. Results in male nad female inferticility (sperm immotile) - bronchiectasis - and recurrent sinusisits - associated with situs inversus
origin of replication
Kartageners syndrome
Elastase is inhibited by
White codon is at the 3 prime end of a tRNA

6. Inhibits by binding to the potassium side
nucleotide
Oubain
Neurofilaments
Step Three of RNA processing

7. Three amino acids necessary for purine synthesis= glutamine - aspartate and glycine
Higher the cholesterol or long saturated fatty acid content
DNA pol III
Heterochromatin
Gag on pure gold

8. Blocks denovo purine synthesis
origin of replication
6MP
Initial transcript without processing is known as
Base excision repair

9. G1 - S - G2 - Mitosis
RNA processing in eukaryotes occurs
Cell cycle order
Associations of Ehlers Danlos
Digoxin (cardiac glycosides)

10. Read froma fixed starting point as a continous sequenecs of bases
tRNA aminoacylation
commaless - non - overlapping
Tetracyclines
Purines

11. Less condensed - transciptionally active=eu truly transcobed
unambiguous
degenerate or redundant
Single Strand DNA Repair types
Euchromatin

12. Poly adenylation
step two of RNA processing
Cilia structure
capped and tail transcript is called
Eukaroytes

13. Vimentin - desmin - cytockeratin - glial fibrillary acid proteins - neurofilaments
Molecular motor protiesn
Macrolides
Step one of RNA processing
intermediate filaments

14. MRNA
step two of RNA processing
Rough ER
capped and tail transcript is called
Introns

15. 1P (blocked by tetracycline)
Which end of a growing DNA strand is the target
Loading tRNA on to ribosome energy requirement
polyadenylation does/does not require a template
Guanine has a

16. VItamin C
What does the hydroxylation of proline and lysine require
Excocytosis of collagen
Double Strand DNA repair
Single Strand DNA Repair types

17. Hydroxy proline and hydroxylysine
The only histone not on the core
Hydroxylation of which amino acids are attached to Glycine to form collagen
What type of collagen is most affected in Ehlers Danlos
Aminoacylt - tRNA synthetase

18. Bind 50S blocking translocation
The only histone not on the core
Osteogenesis Imperfecta
Glycosolation
Macrolides

19. Contain the actual genetic information coding for protein
Exons
What type of collagen is most affected in Ehlers Danlos
Prokaryotes
Griseofulvin

20. Asymmetric fluid bilayer - contains - cholesterol - phospholipids - sphingoplipids - glycolipids - and protiends
Plasma membrane composition
mRNA stop codons
What does the hydroxylation of proline and lysine require
purines

21. Inhibits the atpase which increases intracellular sodium which increases intracellular calcium increases cardiaccontractility
Digoxin (cardiac glycosides)
Gag on pure gold
Chediak Higashi syndrome
pyrimadines

22. Epithelial cells
Cholchicine
cytokeratin
Type IV collagen is an important structural component of...
Exons

23. Site where RNA polymerase and multiple other transciption factors bind to DNA upstream from gene locus (AT rich upstream sequence with TATA and CAAT boxes)
Prokaryote RNA pol
promoter
DNA pol III
Non homologous end joining

24. Brings together 2 ends of DNA fragments no requirement for homology
Chediak Higashi syndrome
promoter
Non homologous end joining
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by

25. Same aa often base change in 3rd position of codon
Macrolides
Post - translational modifications
silent mutation
Alternate splicing

26. The 5prime end (energy for the bond)
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
mRNA start codons
Which end of the nucleotide has the triphosphate
Higher the cholesterol or long saturated fatty acid content

27. Inhibits thymidylate synthase down thymine
5FU
Chediak Higashi syndrome
Step Three of RNA processing
Post - translational modifications

28. HS1 - HSB - H2 - H4
histone octamer names
Single Strand DNA Repair types
Cilia structure
Cholchicine

29. Scrutinizes aa before and after it binds to tRNA. If incorrect bond is hydrolyzed.
Base excision repair
Aminoacylt - tRNA synthetase
microtubule
Cholchicine

30. You glyucosolate hte pro - alpha chain lysine resudens and form procollagen (triple helix of alpha chains)
Cholchicine
5FU
Glycosolation
degenerate or redundant

31. Rampant - Massive - TIny rRNA is most common - then mRNA and then tRNA
Thymine has a
Which is the most and least abundant type of RNA
RNA polymerases in eukaryotes
Chediak Higashi syndrome

32. Methionine - which may be removed before translation is completed
In eukaryotes the starting amino acid is...
Covalent alterations
nonsense
Gag on pure gold

33. Inhibits 50S peptidyl transferase
What type of collagen is most affected in Ehlers Danlos
Which end of the nucleotide has the triphosphate
Cyclins
Chloramphenicol

34. Uracil
Plasma membrane composition
Higher the cholesterol or long saturated fatty acid content
Total energy expenditure requirement for translocation
Deamination of cytosine makes

35. Genetic bone disorder (brittle bone disease) type 1 colalgen - fractures (during birth) 2) Blue sclerae 3) hearing loss 4) dental imperfections 1:10000 may be confused with child abuse
Order of mitosis
Osteogenesis Imperfecta
Permanent cells
Proofreading function in eukaryotic RNA

36. CCA AT 3 PRIME END
GFAP
Osteogenesis Imperfecta
White codon is at the 3 prime end of a tRNA
Immunohistochemical stains vimentin

37. Never go to Go divide rapidly with short G1 bone marrow - gut epithelium - skin - hair follicles
Replication fork
trimethoprim
Labile
Step one of RNA processing

38. Inhibit DNA gyrase (specific prokaryotic topoisomerase)
Base excision repair
Fluoroquinolones
In eukaryotes the starting amino acid is...
Cell cycle

39. AD and AR- associated iwth joint dislocation - berry aneurysms - organ rupture
Associations of Ehlers Danlos
GFAP
Chloramphenicol
Step Three of RNA processing

40. GTP
CDKs
tRNA gripping and going places
pyrimadines
Type IV collagen is an important structural component of...

41. Particular sequnece in genomre where DNA replication begins. May be single (prokaryotes) or multiple (eukaryotes)
universal
Which is the most and least abundant type of RNA
origin of replication
Molecular motor protiesn

42. UGA - UAG - UAA
Total energy expenditure requirement for translocation
Excocytosis of collagen
mRNA stop codons
Single Strand DNA Repair types

43. No proofreading function but can initiate chains. RNA poymerase II opens DNA at promoter site
actin and myosin
Proofreading function in eukaryotic RNA
Common amino acids in elastin
C- G bond

44. Strethchy protein within lungs - large artiers - elastic liaments - vocal cords - ligamenta flava)
Guanine has a
Elastin
Introns
Prokaryote RNA pol

45. Anti cancer - act on microtubules
Vincristine/Vinblastine
Cell cycle order
Common amino acids in elastin
Going APE

46. Inhibit formation of the initation complex and cause misreading of mRNA
Aminoglycosides
Smooth ER
Cell cycle
Alports syndrome

47. Y shaped region along DNA template where leading and lagging strands are syntehsized
Common amino acids in elastin
universal
Replication fork
Covalent alterations

48. Regulatory proteins that control cell cycle events; phase specific; activated CDKs
Covalent alterations
Cyclins
Which end of the tRNA is the amino acid bound to?
Translocation

49. Stretch of DNA that alters gene expression by binding transcription factors
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
Enhancer
Nucleotide excision repair
Replication fork

50. RNA polymerase I makes rRNA - RNA pol II makes mRNA - RNA pol III makes tRNA
Paclitaxil
RNA polymerases in eukaryotes
Purines
Mebendazole/thiabendazole