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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. G1 - S - G2 - Mitosis
The only histone not on the core
Cell cycle order
Silencer
Termination
2. Anti cancer - act on microtubules
Step Three of RNA processing
5FU
Vincristine/Vinblastine
Initial transcript without processing is known as
3. Inhibits 50S peptidyl transferase
Example of permanent cells
Chloramphenicol
Double Strand DNA repair
Tetracyclines
4. Tansport cellular cargo toward opposite ends of microtubule tracks
universal
microtubule
Molecular motor protiesn
single stranded binding proteinds
5. UGA - UAG - UAA
transversion
Griseofulvin
mRNA stop codons
Primase
6. Phosphorylation - glycosloation - hyderoxylation
A- T
Covalent alterations
desmin
Introns
7. VItamin C
5FU
RNA processing in eukaryotes occurs
Osteogenesis Imperfecta
What does the hydroxylation of proline and lysine require
8. Strethchy protein within lungs - large artiers - elastic liaments - vocal cords - ligamenta flava)
Ehlers Danlos
Elastin
single stranded binding proteinds
Paclitaxil
9. Made from IMP precursor
Xeroderma pigmentosum
Heterochromatin
purines
promoter
10. Same aa often base change in 3rd position of codon
Immunohistochemical stains vimentin
histone octamer names
Hydroxylation of which amino acids are attached to Glycine to form collagen
silent mutation
11. Makes an RNA primer on which DNA polymerase II can initiate replication
Collagen
intermediate filaments
Which end of the tRNA is the amino acid bound to?
Primase
12. ATP
RNA polymerases in eukaryotes
tRNA activation
Exons
Glycosolation
13. CUT 1 ring Cut the Py
Cell cycle
Pyrimidines
Gag on pure gold
tRNA activation
14. The 3 prime hydroxyl of the nascent chain is the target
Which end of a growing DNA strand is the target
6MP
Eukaroytes
RNA polymerases in eukaryotes
15. Genetic bone disorder (brittle bone disease) type 1 colalgen - fractures (during birth) 2) Blue sclerae 3) hearing loss 4) dental imperfections 1:10000 may be confused with child abuse
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
missense mutation
Osteogenesis Imperfecta
Digoxin (cardiac glycosides)
16. Even 40S 60S =80S
Functional organization of the gene
Eukaroytes
degenerate or redundant
Griseofulvin
17. Anti breast cancer - acts on mts
Aminoacylt - tRNA synthetase
Paclitaxil
Which is the most and least abundant type of RNA
Immunohistochemical stains vimentin
18. 1P blocked by chloramphenicaol and macrolide
Translocation
AUG codes For what in prokaryotes
Replication fork
helicase
19. Ketone
Associations of Ehlers Danlos
Xeroderma pigmentosum
6MP
Guanine has a
20. ATP ase that links peripheral 9 doublets and causes bending of cilium by differential sliding of doublets
GFAP
Axonemal dyenin
DNA pol III
commaless - non - overlapping
21. Condensed - transciptionally inactive HC- Highly condensed
Rough ER
Heterochromatin
Functional organization of the gene
Kartageners syndrome
22. Uracil
Alports syndrome
Elastase is inhibited by
Deamination of cytosine makes
single stranded binding proteinds
23. AD and AR- associated iwth joint dislocation - berry aneurysms - organ rupture
5FU
Cholchicine
Permanent cells
Associations of Ehlers Danlos
24. Vimentin - desmin - cytockeratin - glial fibrillary acid proteins - neurofilaments
helicase
intermediate filaments
tRNA Structure
Alports syndrome
25. Intervening noncoding segments of DNA
origin of replication
microtubule
nucleotide
Introns
26. 1) primary transcript combines with snRNPs and other proteins to form spliceosome 2) lariat shaped intermediate is generated 3) Lariat is removed and released to precisely join 2 exons
Which is the most and least abundant type of RNA
Type IV collagen is an important structural component of...
Steps in splicing
Macrolides
27. A malfunction of mismatch repair (MUt L etc..)
Elastin
Introns
Hereditary non polyposis colorectal cancer
Translocation
28. Promoter - enhancer - promoter - TATA- transcription initiation site - coding region (including exons and introns) and then the AATAAA
silent mutation
trimethoprim
capped and tail transcript is called
Functional organization of the gene
29. Particular sequnece in genomre where DNA replication begins. May be single (prokaryotes) or multiple (eukaryotes)
Higher the cholesterol or long saturated fatty acid content
Covalent alterations
Permanent cells
origin of replication
30. Commonly results in dramatic decrease in amount of gene transcribed
Promoter mutation
Associations of Ehlers Danlos
step two of RNA processing
Prokaryotes
31. Aminoacyl - tRNA binds to A site 2) peptidyltransferase catalyzes peptide bond formation transfers growing polypeptie to amino acid in A site 3) ribosome advances 3 nucleotides toward the 3 prime end of RNA moving peptiydyl RNA to P site
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
Steps in splicing
Outside the cell what processing must be done in procolalgen
Elongation
32. Activated by GTP hydrolosis initiation factors help assembel the 40 S ribosomal subunites with the initiatior tRNA and are released whent he mRNA and the ribosomal subunit assemple with the complex
Deamination of cytosine makes
RNA polymerases in eukaryotes
Steps in splicing
Protein synthesis initiation
33. Binds 50S blocking translocation
Clindamycin
Which is the most and least abundant type of RNA
DNA pol III
methionine is only encoded by
34. Prokaryotic only. Degrades RNA primer and fills in the gap with DNA (5 prime to 3 prime exonuclease)
DNA pol I
Cell cycle order
Stable (quiescent)
C- G bond
35. 5 prime to 3 prime
Free ribosomes
mRNA is syntehsized in which direction?
helicase
Steps in splicing
36. ATP- AMP (2 phosphoanhydride bonds)
tRNA aminoacylation
Replication fork
mRNA stop codons
origin of replication
37. Connective tissue
GFAP
Cyclin - CDK
intermediate filaments
Immunohistochemical stains vimentin
38. Bind 50S blocking translocation
Macrolides
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
Primase
CDKs
39. Brings together 2 ends of DNA fragments no requirement for homology
Non homologous end joining
Cell cycle order
Prokaryote RNA pol
Chloramphenicol
40. Inhibits the atpase which increases intracellular sodium which increases intracellular calcium increases cardiaccontractility
What does the hydroxylation of proline and lysine require
Digoxin (cardiac glycosides)
intermediate filaments
Labile
41. Inhibits thymidylate synthase down thymine
tRNA
5FU
Fluoroquinolones
Single Strand DNA Repair types
42. Contain the actual genetic information coding for protein
RNA processing in eukaryotes occurs
origin of replication
Exons
Macrolides
43. Exocytose procollagen into extracellylar sace
silent mutation
Excocytosis of collagen
The only histone not on the core
Oubain
44. Nucleotide excision repair - Base Excision repair - Mismath repair
Gag on pure gold
Guanine has a
Introns
Single Strand DNA Repair types
45. Xlinked recessive IV collagen bm - kidney - ear and eye -- nephritis and defness ocular disturbances
What ties teh nucleosome together
Mismatch repair
helicase
Alports syndrome
46. Methyl THYmine has a meTHYl
Axonemal dyenin
Thymine has a
Example of permanent cells
Immunohistochemical stains vimentin
47. Inhbits RNA pol II (found in death cap mushrooms)
Mebendazole/thiabendazole
alpha amintin
Smooth ER
Termination
48. Blocks denovo purine synthesis
single stranded binding proteinds
Stable (quiescent)
6MP
transition
49. Responsible for the accuracy of amino acid selection
GFAP
Which end of the nucleotide has the triphosphate
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
RNA processing in eukaryotes occurs
50. HS1 - HSB - H2 - H4
Enhancer
histone octamer names
transversion
Elongation