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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Negatively charged DNA loops twice around histone octamers create a nucloesome bead.
chromatin structure
6MP
desmin
nonsense
2. Site of dteroid synthesis and detoxification of druigs and poisons (liver hepatocytes and steroid horomore adrenal cortex)
RNA processing in eukaryotes occurs
Smooth ER
tRNA
tRNA activation
3. Immotile cilia due to a dyenin arm defect. Results in male nad female inferticility (sperm immotile) - bronchiectasis - and recurrent sinusisits - associated with situs inversus
actin and myosin
Osteogenesis Imperfecta
Kartageners syndrome
universal
4. Asymmetric fluid bilayer - contains - cholesterol - phospholipids - sphingoplipids - glycolipids - and protiends
Plasma membrane composition
Type IV collagen is an important structural component of...
nonsense
capped and tail transcript is called
5. Create a nick in the helix to relieve supercoils created during replication
C- G bond
DNA topoisomerases
dyenin
Promoter mutation
6. Specific glycosylases recognize and remove damaged bases - AP endonuclease cuts DNA at pyrimidne site - empty sugar is removed and the gap is filled and resealed
intermediate filaments
microtubule
Proofreading function in eukaryotic RNA
Base excision repair
7. Methyl THYmine has a meTHYl
Translocation
Immunohistochemical stains vimentin
Thymine has a
Rough ER
8. Prokaryotic only. Degrades RNA primer and fills in the gap with DNA (5 prime to 3 prime exonuclease)
DNA pol I
tRNA gripping and going places
Digoxin (cardiac glycosides)
Prokaryote RNA pol
9. Enter G1 from G0 when stimulated Hepatocytes/lymphocytes
Stable (quiescent)
Chloramphenicol
Cholchicine
Outside the cell what processing must be done in procolalgen
10. Changed aaconservative - new aa is similar in chemical structure
Elastase is inhibited by
methionine is only encoded by
missense mutation
5FU
11. Inhibits ribonucleotide reductase
What does the hydroxylation of proline and lysine require
Order of mitosis
hydroxyurea
missense mutation
12. Inhibits by binding to the potassium side
Neurofilaments
Rough ER
Oubain
Euchromatin
13. Ketone
Plasma membrane composition
Guanine has a
Collagen
microtubule
14. Trimming removal of n or c terminal propeptides from zymogens to generate mature proteinds
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
Single Strand DNA Repair types
Chediak Higashi syndrome
Post - translational modifications
15. Brings together 2 ends of DNA fragments no requirement for homology
Eukaroytes
Tropocollagen cross links between_____ to form____
Non homologous end joining
tRNA Structure
16. VItamin C
Mismatch repair
In eukaryotes the starting amino acid is...
Tumor Suppressors
What does the hydroxylation of proline and lysine require
17. Strethchy protein within lungs - large artiers - elastic liaments - vocal cords - ligamenta flava)
Elastin
Proteosomal degradation
Eukaroytes
Oubain
18. GTP
tRNA gripping and going places
Heterochromatin
mRNA stop codons
Protein synthesis is in which direction
19. You glyucosolate hte pro - alpha chain lysine resudens and form procollagen (triple helix of alpha chains)
Promoter mutation
Chloramphenicol
Mismatch repair
Glycosolation
20. Has enough energy to created the peptide bond
the tRNA- amino acid bond
alpha amintin
tRNA activation
Paclitaxil
21. CUT 1 ring Cut the Py
Non homologous end joining
Labile
Pyrimidines
Oubain
22. Cleave terminal regions of procollagen to transform into insoluable tropocolagen
Outside the cell what processing must be done in procolalgen
Loading tRNA on to ribosome energy requirement
Enhancers and silencer may be located_____
Alports syndrome
23. Seals
DNA ligase
missense mutation
Hydroxylation of which amino acids are attached to Glycine to form collagen
Elastin
24. Completed protein is released from ribosme through simple hydrolosis and dissociates
Termination
Steps in splicing
microtubule
commaless - non - overlapping
25. Inhibits bacterials dihydrofolate reducatese down thymine
Aminoacylt - tRNA synthetase
histone octamer names
trimethoprim
Elongation
26. Change resulting in misreading of all nucleotides downstream - usually resulting in a truncated non functional protien
frame shift
Rough ER
Steps in splicing
cytokeratin
27. Attachment of ubiquitin to defective proteinds to tag them for breakdown
Mismatch repair
purines
Proteosomal degradation
Going APE
28. Neurons
Neurofilaments
Immunohistochemical stains vimentin
Permanent cells
Proteosomal degradation
29. Hydroxy proline and hydroxylysine
silent mutation
Hydroxylation of which amino acids are attached to Glycine to form collagen
DNA ligase
Thymine has a
30. G1 - S - G2 - Mitosis
Cell cycle order
actin and myosin
Step one of RNA processing
Prokaryote RNA pol
31. Activated by GTP hydrolosis initiation factors help assembel the 40 S ribosomal subunites with the initiatior tRNA and are released whent he mRNA and the ribosomal subunit assemple with the complex
Fluoroquinolones
Protein synthesis initiation
Aminoacylt - tRNA synthetase
Proteosomal degradation
32. Methionine - which may be removed before translation is completed
RNA processing in eukaryotes occurs
histone octamer names
Double Strand DNA repair
In eukaryotes the starting amino acid is...
33. CCA AT 3 PRIME END
White codon is at the 3 prime end of a tRNA
silent mutation
step two of RNA processing
Enhancer
34. Accurate base pairing is required only in the first 2 nucleotide positions of an mRNA so codons differing ht e3rd wobble psoition may code for the same tRNA/amino acid code
Associations of Ehlers Danlos
Free ribosomes
tRNA
AUG codes For what in prokaryotes
35. Site where RNA polymerase and multiple other transciption factors bind to DNA upstream from gene locus (AT rich upstream sequence with TATA and CAAT boxes)
Prokaryote RNA pol
commaless - non - overlapping
promoter
Alports syndrome
36. Unwinds DNA template at replication fork
Step one of RNA processing
Mismatch repair
helicase
tRNA
37. 1 RNA polymerase (multisubunite complex) makes all 3 kinds of RNA
CDKs
Prokaryote RNA pol
Elastase is inhibited by
Tetracyclines
38. H1
The only histone not on the core
Going APE
Collagedn synthesis where?
Deamination of cytosine makes
39. Be So Totatally Cool Read Books (bOne - CarTWOlage - Threeticular - Type IV under the floor)
Enhancers and silencer may be located_____
Collagen
AUG codes For what in prokaryotes
universal
40. Microvilli - muscle contraction - cytokinesis - adhering juntions
Associations of Ehlers Danlos
actin and myosin
origin of replication
Purines
41. Xlinked recessive IV collagen bm - kidney - ear and eye -- nephritis and defness ocular disturbances
chromatin structure
Deamination of cytosine makes
Alports syndrome
Going APE
42. Commonly results in dramatic decrease in amount of gene transcribed
Guanine has a
intermediate filaments
Promoter mutation
Primase
43. 1P (blocked by tetracycline)
Xeroderma pigmentosum
Loading tRNA on to ribosome energy requirement
mRNA stop codons
Primase
44. The 3 prime hydroxyl of the nascent chain is the target
Cyclins
Thymine has a
microtubule
Which end of a growing DNA strand is the target
45. Phosphorylation - glycosloation - hyderoxylation
Alports syndrome
hydroxyurea
Fluoroquinolones
Covalent alterations
46. Condensed - transciptionally inactive HC- Highly condensed
Cell cycle order
Heterochromatin
Euchromatin
Alports syndrome
47. 2 H bonds greater GC content greater melting point
CDKs
Heterochromatin
capped and tail transcript is called
A- T
48. Exocytose procollagen into extracellylar sace
Chloramphenicol
5FU
Chediak Higashi syndrome
Excocytosis of collagen
49. Cilia - glagella - mitotic spindle - neurons - centrioles
Tetracyclines
Guanine has a
silent mutation
microtubule
50. Same aa often base change in 3rd position of codon
Loading tRNA on to ribosome energy requirement
DNA topoisomerases
Labile
silent mutation