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Test your basic knowledge |
First Aid: Biochemistry Molecular
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Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
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study here
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Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Prevents stranges from reannealing
single stranded binding proteinds
Clindamycin
Gag on pure gold
Hydroxylation of which amino acids are attached to Glycine to form collagen
2. Specific endonucleases release the oligonucleotide containing damaged bases. DNA polymerase and logase fill and resealt eh gap
Base excision repair
unambiguous
Molecular motor protiesn
Nucleotide excision repair
3. AUG inAUGurates protein synthesis
methionine is only encoded by
mRNA start codons
Collagen
Immunohistochemical stains vimentin
4. Lysine/hydroxylysine and combines to form collagen
Tropocollagen cross links between_____ to form____
CDKs
Nucleotide excision repair
Enhancers and silencer may be located_____
5. Completed protein is released from ribosme through simple hydrolosis and dissociates
Termination
Permanent cells
Outside the cell what processing must be done in procolalgen
Enhancers and silencer may be located_____
6. Anterograde to microtubule
kinesin
Griseofulvin
Protein synthesis is in which direction
Vincristine/Vinblastine
7. Particular sequnece in genomre where DNA replication begins. May be single (prokaryotes) or multiple (eukaryotes)
origin of replication
Protein synthesis initiation
Xeroderma pigmentosum
Which end of a growing DNA strand is the target
8. Inhibits ribonucleotide reductase
Mebendazole/thiabendazole
hydroxyurea
Purines
Prokaryotes
9. Neurons - skeletal - and cardiac muscle - RBCs
silent mutation
Post - translational modifications
Step Three of RNA processing
Example of permanent cells
10. P53 and RB normally inhibit g1 to S progression
capped and tail transcript is called
Gag on pure gold
Prokaryote RNA pol
Tumor Suppressors
11. Microtubule polymerization defect resulting in lowered phagocytosis. results in recurrent pyogenic infections - partial albinism and peripheral neuropathy
Loading tRNA on to ribosome energy requirement
Prokaryote RNA pol
Type IV collagen is an important structural component of...
Chediak Higashi syndrome
12. Xlinked recessive IV collagen bm - kidney - ear and eye -- nephritis and defness ocular disturbances
Alports syndrome
nucleosid
Step one of RNA processing
nucleotide
13. Cleave terminal regions of procollagen to transform into insoluable tropocolagen
The only histone not on the core
Paclitaxil
actin and myosin
Outside the cell what processing must be done in procolalgen
14. Inhibits by binding to the potassium side
tRNA gripping and going places
Which is the most and least abundant type of RNA
Where do introns and exons stay
Oubain
15. Made from IMP precursor
Exons
purines
What type of collagen is most affected in Ehlers Danlos
Step one of RNA processing
16. Cilia - glagella - mitotic spindle - neurons - centrioles
GFAP
microtubule
Where do introns and exons stay
mRNA is syntehsized in which direction?
17. Exocytose procollagen into extracellylar sace
Mismatch repair
Enhancers and silencer may be located_____
What ties teh nucleosome together
Excocytosis of collagen
18. Substituting a pyramidine for a pyrimadine
transition
Molecular motor protiesn
RNA polymerases in eukaryotes
Steps in splicing
19. 9+2 arrangement of microtubules -
Total energy expenditure requirement for translocation
Gag on pure gold
Cilia structure
mRNA start codons
20. ATP
Replication fork
tRNA activation
mRNA start codons
Fluoroquinolones
21. Unwinds DNA template at replication fork
helicase
Pyrimidines
Elastin is broken down by
microtubule
22. Change resulting in early stop codon
Introns
nonsense
Stable (quiescent)
Primase
23. Changed aaconservative - new aa is similar in chemical structure
Elastin is broken down by
missense mutation
DNA pol III
The only histone not on the core
24. Even 40S 60S =80S
Cyclins
Base excision repair
Eukaroytes
What type of collagen is most affected in Ehlers Danlos
25. Neuroglia
GFAP
Higher the cholesterol or long saturated fatty acid content
Replication fork
Vincristine/Vinblastine
26. Blocks denovo purine synthesis
Introns
6MP
CDKs
Elastin is broken down by
27. Be So Totatally Cool Read Books (bOne - CarTWOlage - Threeticular - Type IV under the floor)
degenerate or redundant
Collagen
Ehlers Danlos
single stranded binding proteinds
28. 1 RNA polymerase (multisubunite complex) makes all 3 kinds of RNA
pyrimadines
Prokaryote RNA pol
polyadenylation does/does not require a template
actin and myosin
29. Binds 50S blocking translocation
Neurofilaments
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
mRNA stop codons
Clindamycin
30. Attachment of ubiquitin to defective proteinds to tag them for breakdown
Prokaryote RNA pol
Proteosomal degradation
Enhancers and silencer may be located_____
Which is the most and least abundant type of RNA
31. Non homologous end joining
Osteogenesis Imperfecta
Double Strand DNA repair
Digoxin (cardiac glycosides)
Methotrexate
32. Brings together 2 ends of DNA fragments no requirement for homology
Non homologous end joining
Covalent alterations
Digoxin (cardiac glycosides)
histone octamer names
33. Type III
Mebendazole/thiabendazole
mRNA stop codons
dyenin
What type of collagen is most affected in Ehlers Danlos
34. Codes for formyl methionine (f - Met)
intermediate filaments
AUG codes For what in prokaryotes
Oubain
Hydroxylation of which amino acids are attached to Glycine to form collagen
35. The 3 prime end
single stranded binding proteinds
Which end of the tRNA is the amino acid bound to?
Stable (quiescent)
Promoter mutation
36. CCA AT 3 PRIME END
White codon is at the 3 prime end of a tRNA
Enhancers and silencer may be located_____
tRNA activation
Pyrimidines
37. Site where RNA polymerase and multiple other transciption factors bind to DNA upstream from gene locus (AT rich upstream sequence with TATA and CAAT boxes)
promoter
Proofreading function in eukaryotic RNA
mRNA start codons
tRNA activation
38. (A - G) 2 rings Pure As Gold
Purines
capped and tail transcript is called
mRNA start codons
DNA pol I
39. 1P blocked by chloramphenicaol and macrolide
Mismatch repair
Translocation
Rough ER
6MP
40. Prophas - metaphase - anaphase telophase
Protein synthesis is in which direction
Heterochromatin
Example of permanent cells
Order of mitosis
41. Y shaped region along DNA template where leading and lagging strands are syntehsized
Elastin
Hydroxylation of which amino acids are attached to Glycine to form collagen
Enhancer
Replication fork
42. Methionine - which may be removed before translation is completed
Elastin
Silencer
In eukaryotes the starting amino acid is...
mRNA stop codons
43. Base+ribose+phosphate linked by a phosphodiester bond
Purines
nucleotide
DNA topoisomerases
Guanine has a
44. Microvilli - muscle contraction - cytokinesis - adhering juntions
Heterochromatin
Alternate splicing
Pyrimidines
actin and myosin
45. A site - incoming aminoacyl tRNA - Psite accomodates growing Peptide - E site holds EmplytRNA as it exits
Going APE
Sodium K ATPase
transversion
What does the hydroxylation of proline and lysine require
46. 4 high enrgy bonds
Total energy expenditure requirement for translocation
Cilia structure
Clindamycin
Elastase is inhibited by
47. 5 prime to 3 prime
Outside the cell what processing must be done in procolalgen
mRNA is syntehsized in which direction?
Silencer
Cyclins
48. Promoter - enhancer - promoter - TATA- transcription initiation site - coding region (including exons and introns) and then the AATAAA
Functional organization of the gene
nonsense
Promoter mutation
Total energy expenditure requirement for translocation
49. A malfunction of mismatch repair (MUt L etc..)
Base excision repair
Hereditary non polyposis colorectal cancer
Eukaroytes
Non homologous end joining
50. H1 string
Oubain
What ties teh nucleosome together
kinesin
tRNA aminoacylation
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