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First Aid: Biochemistry Molecular

Instructions:
  • Answer 50 questions in 15 minutes.
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  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Inhibits bacterials dihydrofolate reducatese down thymine






2. ATP






3. Anterograde to microtubule






4. AUG inAUGurates protein synthesis






5. Inhibit DNA gyrase (specific prokaryotic topoisomerase)






6. Cilia - glagella - mitotic spindle - neurons - centrioles






7. Splicing out of introns






8. In the nucleus after transcitpion and only processed RNA is transporte out of the nucleus






9. The 3 prime hydroxyl of the nascent chain is the target






10. Antigout - acts on mts






11. Prokaryotic only. Degrades RNA primer and fills in the gap with DNA (5 prime to 3 prime exonuclease)






12. Binds 50S blocking translocation






13. Uracil






14. Seals






15. Completed protein is released from ribosme through simple hydrolosis and dissociates






16. Negatively charged DNA loops twice around histone octamers create a nucloesome bead.






17. H1 string






18. Blocks denovo purine synthesis






19. Anti cancer - act on microtubules






20. 5 prime to 3 prime






21. Elastase






22. Made from orogate precuror with PRPP added later






23. Checkpoints control transition between phases of cell cycle. regulated by cyclins - CDKs and tumor suppressors. Mitosis (shortest phse)






24. Vimentin - desmin - cytockeratin - glial fibrillary acid proteins - neurofilaments






25. 1P (blocked by tetracycline)






26. Methionine - which may be removed before translation is completed






27. 1 RNA polymerase (multisubunite complex) makes all 3 kinds of RNA






28. Odd 30S plus 50 S=70S






29. Immotile cilia due to a dyenin arm defect. Results in male nad female inferticility (sperm immotile) - bronchiectasis - and recurrent sinusisits - associated with situs inversus






30. Type III






31. Nucleotide excision repair - Base Excision repair - Mismath repair






32. Promoter - enhancer - promoter - TATA- transcription initiation site - coding region (including exons and introns) and then the AATAAA






33. Introns stay In the nucleus whereas EXons EXit and are EXpressed






34. Inhibits by binding to the potassium side






35. DNA And RNA synthesized in the 5-3 direction






36. Inhibits ribonucleotide reductase






37. Bind 30S subunit preventing attachment of aminoacyl - tRNA






38. Site of dteroid synthesis and detoxification of druigs and poisons (liver hepatocytes and steroid horomore adrenal cortex)






39. Different exons can be combined to make nique protiens in different times






40. Remain in G0 regenerate from stem cells






41. Mutation in nucleotide excision repair Dry skin with melanoma and other cancers






42. Accurate base pairing is required only in the first 2 nucleotide positions of an mRNA so codons differing ht e3rd wobble psoition may code for the same tRNA/amino acid code






43. Cylindrical structure composed of helical array of plymerized dimers of alpha and beta tubulin - flagella - cilia - mitotic spindle - grows slowly collapses quickly






44. Proline - glycine






45. The 3 prime end






46. Unattached to any membrane; site of cytosolic and organeller prtoeins






47. Even 40S 60S =80S






48. Site where negative regulators bind






49. Greater melting temperature lower fluidity






50. Condensed - transciptionally inactive HC- Highly condensed