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First Aid: Biochemistry Molecular

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Anit helminth - act on microtubules






2. Inhibits ribonucleotide reductase






3. H1 string






4. Connective tissue






5. P53 and RB normally inhibit g1 to S progression






6. Enter G1 from G0 when stimulated Hepatocytes/lymphocytes






7. Anterograde to microtubule






8. Microvilli - muscle contraction - cytokinesis - adhering juntions






9. 2 H bonds greater GC content greater melting point






10. Muscle






11. Checkpoints control transition between phases of cell cycle. regulated by cyclins - CDKs and tumor suppressors. Mitosis (shortest phse)






12. RER translation of collagen alpha chains (preprocollagen) usually Gly-X-Y






13. Cyclin depndent kinases; consituative and inactive






14. Inhibits dihydrofolate reductase down thymine






15. Codes for formyl methionine (f - Met)






16. Cylindrical structure composed of helical array of plymerized dimers of alpha and beta tubulin - flagella - cilia - mitotic spindle - grows slowly collapses quickly






17. Inhibit DNA gyrase (specific prokaryotic topoisomerase)






18. Inhibits by binding to the potassium side






19. Must be both activated and inactivated for cell cycle to progress






20. Cleave terminal regions of procollagen to transform into insoluable tropocolagen






21. Makes an RNA primer on which DNA polymerase II can initiate replication






22. Blocks denovo purine synthesis






23. Negatively charged DNA loops twice around histone octamers create a nucloesome bead.






24. Create a nick in the helix to relieve supercoils created during replication






25. Vimentin - desmin - cytockeratin - glial fibrillary acid proteins - neurofilaments






26. Has enough energy to created the peptide bond






27. Capping on 5 prime end (7 methylguanosine) -






28. Attachment of ubiquitin to defective proteinds to tag them for breakdown






29. Accurate base pairing is required only in the first 2 nucleotide positions of an mRNA so codons differing ht e3rd wobble psoition may code for the same tRNA/amino acid code






30. Base+ribose+phosphate linked by a phosphodiester bond






31. RNA polymerase I makes rRNA - RNA pol II makes mRNA - RNA pol III makes tRNA






32. Particular sequnece in genomre where DNA replication begins. May be single (prokaryotes) or multiple (eukaryotes)






33. A malfunction of mismatch repair (MUt L etc..)






34. Be So Totatally Cool Read Books (bOne - CarTWOlage - Threeticular - Type IV under the floor)






35. Close to - far from or even within (in an intron) the gene whose expression it regulates






36. Completed protein is released from ribosme through simple hydrolosis and dissociates






37. Even 40S 60S =80S






38. You glyucosolate hte pro - alpha chain lysine resudens and form procollagen (triple helix of alpha chains)






39. CCA AT 3 PRIME END






40. Less condensed - transciptionally active=eu truly transcobed






41. Methyl THYmine has a meTHYl






42. One codon AUG






43. Substituting a purine for a pyrimdine or vice versa






44. Commonly results in dramatic decrease in amount of gene transcribed






45. Site where RNA polymerase and multiple other transciption factors bind to DNA upstream from gene locus (AT rich upstream sequence with TATA and CAAT boxes)






46. No proofreading function but can initiate chains. RNA poymerase II opens DNA at promoter site






47. A site - incoming aminoacyl tRNA - Psite accomodates growing Peptide - E site holds EmplytRNA as it exits






48. Introns stay In the nucleus whereas EXons EXit and are EXpressed






49. Aminoacyl - tRNA binds to A site 2) peptidyltransferase catalyzes peptide bond formation transfers growing polypeptie to amino acid in A site 3) ribosome advances 3 nucleotides toward the 3 prime end of RNA moving peptiydyl RNA to P site






50. Faulty collagen synthesis causing 1) hyperextensible skin 2) tendency to bleed 3) hypermobile joints