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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Odd 30S plus 50 S=70S
Prokaryotes
Smooth ER
C- G bond
Digoxin (cardiac glycosides)
2. A site - incoming aminoacyl tRNA - Psite accomodates growing Peptide - E site holds EmplytRNA as it exits
silent mutation
Going APE
RNA processing in eukaryotes occurs
Initial transcript without processing is known as
3. Trimming removal of n or c terminal propeptides from zymogens to generate mature proteinds
Nucleotide excision repair
Post - translational modifications
chromatin structure
Gag on pure gold
4. 4 high enrgy bonds
Protein synthesis is in which direction
Total energy expenditure requirement for translocation
Which end of the nucleotide has the triphosphate
degenerate or redundant
5. Phosphorylation - glycosloation - hyderoxylation
single stranded binding proteinds
Digoxin (cardiac glycosides)
Covalent alterations
5FU
6. Intervening noncoding segments of DNA
Introns
Total energy expenditure requirement for translocation
polyadenylation does/does not require a template
nonsense
7. Attachment of ubiquitin to defective proteinds to tag them for breakdown
Smooth ER
Proteosomal degradation
tRNA
Double Strand DNA repair
8. H1
alpha amintin
desmin
Oubain
The only histone not on the core
9. Made from IMP precursor
Step one of RNA processing
mRNA start codons
purines
Exons
10. Site of dteroid synthesis and detoxification of druigs and poisons (liver hepatocytes and steroid horomore adrenal cortex)
Protein synthesis initiation
Functional organization of the gene
In eukaryotes the starting amino acid is...
Smooth ER
11. 2 H bonds greater GC content greater melting point
tRNA gripping and going places
6MP
Thymine has a
A- T
12. 9+2 arrangement of microtubules -
Purines
pyrimadines
Cilia structure
Digoxin (cardiac glycosides)
13. Never go to Go divide rapidly with short G1 bone marrow - gut epithelium - skin - hair follicles
Labile
Higher the cholesterol or long saturated fatty acid content
Enhancers and silencer may be located_____
Immunohistochemical stains vimentin
14. You glyucosolate hte pro - alpha chain lysine resudens and form procollagen (triple helix of alpha chains)
purines
Step one of RNA processing
Glycosolation
Mebendazole/thiabendazole
15. ATP ase that links peripheral 9 doublets and causes bending of cilium by differential sliding of doublets
RNA polymerases in eukaryotes
transversion
Axonemal dyenin
Kartageners syndrome
16. Seals
Outside the cell what processing must be done in procolalgen
Immunohistochemical stains vimentin
DNA ligase
GFAP
17. Checkpoints control transition between phases of cell cycle. regulated by cyclins - CDKs and tumor suppressors. Mitosis (shortest phse)
Xeroderma pigmentosum
Cell cycle
What ties teh nucleosome together
Collagen
18. Methionine - which may be removed before translation is completed
degenerate or redundant
5FU
In eukaryotes the starting amino acid is...
Hydroxylation of which amino acids are attached to Glycine to form collagen
19. Muscle
desmin
Aminoglycosides
capped and tail transcript is called
DNA ligase
20. Activated by GTP hydrolosis initiation factors help assembel the 40 S ribosomal subunites with the initiatior tRNA and are released whent he mRNA and the ribosomal subunit assemple with the complex
CDKs
Which end of the nucleotide has the triphosphate
Introns
Protein synthesis initiation
21. Anit helminth - act on microtubules
Which is the most and least abundant type of RNA
Mebendazole/thiabendazole
Elastin is broken down by
Kartageners syndrome
22. 75-90 nucleotides - 2ary structure cloverleaf form anticodon end is opposite 3 prime aminoacyl end
tRNA Structure
Elastin
desmin
Translocation
23. Proline - glycine
Prokaryotes
What type of collagen is most affected in Ehlers Danlos
Common amino acids in elastin
Guanine has a
24. Neurons - skeletal - and cardiac muscle - RBCs
Aminoglycosides
Heterochromatin
tRNA gripping and going places
Example of permanent cells
25. Bind 30S subunit preventing attachment of aminoacyl - tRNA
Going APE
nucleosid
5FU
Tetracyclines
26. Exocytose procollagen into extracellylar sace
White codon is at the 3 prime end of a tRNA
Initial transcript without processing is known as
Excocytosis of collagen
A- T
27. Bind 50S blocking translocation
Order of mitosis
Enhancer
Macrolides
Immunohistochemical stains vimentin
28. ATP
Total energy expenditure requirement for translocation
GFAP
tRNA gripping and going places
tRNA activation
29. Connective tissue
polyadenylation does/does not require a template
methionine is only encoded by
6MP
Immunohistochemical stains vimentin
30. Non homologous end joining
Double Strand DNA repair
Alports syndrome
DNA topoisomerases
Introns
31. Condensed - transciptionally inactive HC- Highly condensed
Collagedn synthesis where?
Fluoroquinolones
Heterochromatin
Cell cycle order
32. Retrograde to microtubules
helicase
histone octamer names
Eukaroytes
dyenin
33. AUG inAUGurates protein synthesis
Alternate splicing
mRNA start codons
cytokeratin
nucleosid
34. Immotile cilia due to a dyenin arm defect. Results in male nad female inferticility (sperm immotile) - bronchiectasis - and recurrent sinusisits - associated with situs inversus
Kartageners syndrome
6MP
Initial transcript without processing is known as
In eukaryotes the starting amino acid is...
35. Ribonucleotide reductase
pyrimadines
Total energy expenditure requirement for translocation
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
Alports syndrome
36. Neuroglia
Hydroxylation of which amino acids are attached to Glycine to form collagen
Prokaryotes
GFAP
Cyclin - CDK
37. Faulty collagen synthesis causing 1) hyperextensible skin 2) tendency to bleed 3) hypermobile joints
Tumor Suppressors
Ehlers Danlos
tRNA gripping and going places
Single Strand DNA Repair types
38. 3 sodium out for 2 potassium in (nout - kin)takes 1 atp and the machine is phosphorylated during the machine cycle
Which is the most and least abundant type of RNA
Sodium K ATPase
Chediak Higashi syndrome
microtubule
39. Type III
Higher the cholesterol or long saturated fatty acid content
histone octamer names
What type of collagen is most affected in Ehlers Danlos
Mebendazole/thiabendazole
40. Antigout - acts on mts
silent mutation
chromatin structure
Cholchicine
promoter
41. Inhibits the atpase which increases intracellular sodium which increases intracellular calcium increases cardiaccontractility
Proofreading function in eukaryotic RNA
Step one of RNA processing
Digoxin (cardiac glycosides)
desmin
42. RNA polymerase I makes rRNA - RNA pol II makes mRNA - RNA pol III makes tRNA
Functional organization of the gene
RNA polymerases in eukaryotes
Digoxin (cardiac glycosides)
Osteogenesis Imperfecta
43. Cylindrical structure composed of helical array of plymerized dimers of alpha and beta tubulin - flagella - cilia - mitotic spindle - grows slowly collapses quickly
microtubule
Oubain
Ehlers Danlos
What type of collagen is most affected in Ehlers Danlos
44. Be So Totatally Cool Read Books (bOne - CarTWOlage - Threeticular - Type IV under the floor)
Macrolides
Prokaryote RNA pol
Collagen
Elongation
45. Genetic bone disorder (brittle bone disease) type 1 colalgen - fractures (during birth) 2) Blue sclerae 3) hearing loss 4) dental imperfections 1:10000 may be confused with child abuse
Termination
Osteogenesis Imperfecta
Cell cycle order
promoter
46. Made from orogate precuror with PRPP added later
Hydroxylation of which amino acids are attached to Glycine to form collagen
dyenin
pyrimadines
Cholchicine
47. Negatively charged DNA loops twice around histone octamers create a nucloesome bead.
kinesin
chromatin structure
the tRNA- amino acid bond
Silencer
48. Inhibits ribonucleotide reductase
nonsense
hydroxyurea
Cilia structure
Excocytosis of collagen
49. Enter G1 from G0 when stimulated Hepatocytes/lymphocytes
Stable (quiescent)
What type of collagen is most affected in Ehlers Danlos
Excocytosis of collagen
Eukaroytes
50. Inhibit formation of the initation complex and cause misreading of mRNA
Prokaryotes
Aminoglycosides
Translocation
intermediate filaments