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Test your basic knowledge |
First Aid: Biochemistry Molecular
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Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
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study here
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Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Odd 30S plus 50 S=70S
Prokaryotes
universal
Permanent cells
Chloramphenicol
2. Xlinked recessive IV collagen bm - kidney - ear and eye -- nephritis and defness ocular disturbances
microtubule
Cilia structure
Enhancers and silencer may be located_____
Alports syndrome
3. Inhibits dihydrofolate reductase down thymine
Which end of the nucleotide has the triphosphate
Cell cycle
Elongation
Methotrexate
4. HS1 - HSB - H2 - H4
Protein synthesis initiation
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
CDKs
histone octamer names
5. Prokaryotic only. Degrades RNA primer and fills in the gap with DNA (5 prime to 3 prime exonuclease)
DNA pol I
Immunohistochemical stains vimentin
promoter
Glycosolation
6. Checkpoints control transition between phases of cell cycle. regulated by cyclins - CDKs and tumor suppressors. Mitosis (shortest phse)
Guanine has a
Cell cycle
tRNA gripping and going places
Hereditary non polyposis colorectal cancer
7. Specific glycosylases recognize and remove damaged bases - AP endonuclease cuts DNA at pyrimidne site - empty sugar is removed and the gap is filled and resealed
Rough ER
Proofreading function in eukaryotic RNA
Prokaryotes
Base excision repair
8. ATP ase that links peripheral 9 doublets and causes bending of cilium by differential sliding of doublets
Functional organization of the gene
Xeroderma pigmentosum
5FU
Axonemal dyenin
9. Each codon specifies only 1 amino acid
unambiguous
Covalent alterations
Cholchicine
DNA ligase
10. Made from orogate precuror with PRPP added later
Purines
chromatin structure
Ehlers Danlos
pyrimadines
11. Bind 50S blocking translocation
Macrolides
Exons
Cholchicine
Elastin
12. 1) primary transcript combines with snRNPs and other proteins to form spliceosome 2) lariat shaped intermediate is generated 3) Lariat is removed and released to precisely join 2 exons
Molecular motor protiesn
DNA pol I
Steps in splicing
Glycosolation
13. Trimming removal of n or c terminal propeptides from zymogens to generate mature proteinds
RNA polymerases in eukaryotes
Post - translational modifications
silent mutation
purines
14. Inhibits bacterials dihydrofolate reducatese down thymine
Griseofulvin
Ehlers Danlos
chromatin structure
trimethoprim
15. Anit helminth - act on microtubules
What does the hydroxylation of proline and lysine require
Ehlers Danlos
Mebendazole/thiabendazole
Cell cycle
16. Epithelial cells
alpha amintin
Protein synthesis is in which direction
Going APE
cytokeratin
17. Bind 30S subunit preventing attachment of aminoacyl - tRNA
Tetracyclines
Elastin
DNA/RNA/Protein syntesis direction
the tRNA- amino acid bond
18. 5 prime to 3 prime
intermediate filaments
mRNA is syntehsized in which direction?
Free ribosomes
actin and myosin
19. Even 40S 60S =80S
Excocytosis of collagen
nonsense
Associations of Ehlers Danlos
Eukaroytes
20. Three amino acids necessary for purine synthesis= glutamine - aspartate and glycine
histone octamer names
Prokaryote RNA pol
Gag on pure gold
frame shift
21. Phosphorylation - glycosloation - hyderoxylation
Outside the cell what processing must be done in procolalgen
trimethoprim
Covalent alterations
RNA polymerases in eukaryotes
22. Cilia - glagella - mitotic spindle - neurons - centrioles
DNA ligase
Kartageners syndrome
silent mutation
microtubule
23. H1
trimethoprim
Digoxin (cardiac glycosides)
Cell cycle order
The only histone not on the core
24. Bm - kidney - ears and eyes
Which end of a growing DNA strand is the target
degenerate or redundant
Elastin
Type IV collagen is an important structural component of...
25. Close to - far from or even within (in an intron) the gene whose expression it regulates
Promoter mutation
Replication fork
Enhancers and silencer may be located_____
Clindamycin
26. Change resulting in misreading of all nucleotides downstream - usually resulting in a truncated non functional protien
pyrimadines
frame shift
Alternate splicing
chromatin structure
27. Type III
universal
What type of collagen is most affected in Ehlers Danlos
White codon is at the 3 prime end of a tRNA
Plasma membrane composition
28. Regulatory proteins that control cell cycle events; phase specific; activated CDKs
Paclitaxil
Cyclins
5FU
transversion
29. Asymmetric fluid bilayer - contains - cholesterol - phospholipids - sphingoplipids - glycolipids - and protiends
desmin
mRNA is syntehsized in which direction?
Plasma membrane composition
tRNA
30. Neurons
Heterochromatin
Neurofilaments
Ehlers Danlos
helicase
31. Nucleotide excision repair - Base Excision repair - Mismath repair
Aminoacylt - tRNA synthetase
Single Strand DNA Repair types
Rough ER
microtubule
32. G1 - S - G2 - Mitosis
Common amino acids in elastin
Which end of the nucleotide has the triphosphate
Cell cycle order
Chediak Higashi syndrome
33. Cyclin depndent kinases; consituative and inactive
microtubule
Exons
CDKs
step two of RNA processing
34. Y shaped region along DNA template where leading and lagging strands are syntehsized
Gag on pure gold
What type of collagen is most affected in Ehlers Danlos
Replication fork
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
35. (A - G) 2 rings Pure As Gold
6MP
The only histone not on the core
Purines
Going APE
36. Rampant - Massive - TIny rRNA is most common - then mRNA and then tRNA
Hydroxylation of which amino acids are attached to Glycine to form collagen
Kartageners syndrome
helicase
Which is the most and least abundant type of RNA
37. Codes for formyl methionine (f - Met)
Prokaryote RNA pol
Translocation
Functional organization of the gene
AUG codes For what in prokaryotes
38. Anti breast cancer - acts on mts
Griseofulvin
chromatin structure
Paclitaxil
nucleosid
39. Made from IMP precursor
Primase
purines
Promoter mutation
frame shift
40. Must be both activated and inactivated for cell cycle to progress
Cyclin - CDK
DNA pol I
Enhancer
Methotrexate
41. Inhibits ribonucleotide reductase
hydroxyurea
Functional organization of the gene
missense mutation
Type IV collagen is an important structural component of...
42. Immotile cilia due to a dyenin arm defect. Results in male nad female inferticility (sperm immotile) - bronchiectasis - and recurrent sinusisits - associated with situs inversus
Clindamycin
Molecular motor protiesn
Kartageners syndrome
Stable (quiescent)
43. 3 sodium out for 2 potassium in (nout - kin)takes 1 atp and the machine is phosphorylated during the machine cycle
Alports syndrome
mRNA start codons
Immunohistochemical stains vimentin
Sodium K ATPase
44. Scrutinizes aa before and after it binds to tRNA. If incorrect bond is hydrolyzed.
Common amino acids in elastin
Proofreading function in eukaryotic RNA
Aminoacylt - tRNA synthetase
Cilia structure
45. Brings together 2 ends of DNA fragments no requirement for homology
Non homologous end joining
Initial transcript without processing is known as
Which end of the tRNA is the amino acid bound to?
hydroxyurea
46. 1P blocked by chloramphenicaol and macrolide
Translocation
Labile
DNA pol I
Aminoglycosides
47. A site - incoming aminoacyl tRNA - Psite accomodates growing Peptide - E site holds EmplytRNA as it exits
mRNA stop codons
Purines
Going APE
Gag on pure gold
48. Read froma fixed starting point as a continous sequenecs of bases
microtubule
Cell cycle order
5FU
commaless - non - overlapping
49. Exocytose procollagen into extracellylar sace
Euchromatin
DNA pol III
Excocytosis of collagen
kinesin
50. 75-90 nucleotides - 2ary structure cloverleaf form anticodon end is opposite 3 prime aminoacyl end
tRNA Structure
Outside the cell what processing must be done in procolalgen
Termination
origin of replication
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