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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Stretch of DNA that alters gene expression by binding transcription factors
Enhancer
Which end of the tRNA is the amino acid bound to?
Heterochromatin
Purines
2. A site - incoming aminoacyl tRNA - Psite accomodates growing Peptide - E site holds EmplytRNA as it exits
Going APE
Termination
Vincristine/Vinblastine
Tetracyclines
3. Prokaryotic only. Elongates leading strand by adding deoxynucleotides to the 3prime end. Elongates laggin strand. 3 prime to 5 prime exonuclease activity
Prokaryotes
Common amino acids in elastin
DNA pol III
purines
4. Completed protein is released from ribosme through simple hydrolosis and dissociates
Associations of Ehlers Danlos
Termination
C- G bond
Clindamycin
5. Genetic bone disorder (brittle bone disease) type 1 colalgen - fractures (during birth) 2) Blue sclerae 3) hearing loss 4) dental imperfections 1:10000 may be confused with child abuse
Osteogenesis Imperfecta
Translocation
Prokaryote RNA pol
tRNA Structure
6. 3 sodium out for 2 potassium in (nout - kin)takes 1 atp and the machine is phosphorylated during the machine cycle
kinesin
the tRNA- amino acid bond
Termination
Sodium K ATPase
7. Inhbits RNA pol II (found in death cap mushrooms)
Smooth ER
Purines
Kartageners syndrome
alpha amintin
8. Xlinked recessive IV collagen bm - kidney - ear and eye -- nephritis and defness ocular disturbances
Initial transcript without processing is known as
What does the hydroxylation of proline and lysine require
C- G bond
Alports syndrome
9. CCA AT 3 PRIME END
the tRNA- amino acid bond
White codon is at the 3 prime end of a tRNA
Which end of a growing DNA strand is the target
Cholchicine
10. 75-90 nucleotides - 2ary structure cloverleaf form anticodon end is opposite 3 prime aminoacyl end
Sodium K ATPase
tRNA Structure
Cyclin - CDK
Gag on pure gold
11. Checkpoints control transition between phases of cell cycle. regulated by cyclins - CDKs and tumor suppressors. Mitosis (shortest phse)
Methotrexate
Permanent cells
Cell cycle
Protein synthesis is in which direction
12. The 3 prime end
alpha amintin
degenerate or redundant
Introns
Which end of the tRNA is the amino acid bound to?
13. Odd 30S plus 50 S=70S
Aminoglycosides
Prokaryotes
the tRNA- amino acid bond
What type of collagen is most affected in Ehlers Danlos
14. The 3 prime hydroxyl of the nascent chain is the target
mRNA start codons
Termination
Enhancer
Which end of a growing DNA strand is the target
15. Has enough energy to created the peptide bond
Elongation
Order of mitosis
Step one of RNA processing
the tRNA- amino acid bond
16. Bind 30S subunit preventing attachment of aminoacyl - tRNA
nucleosid
Tetracyclines
Which end of a growing DNA strand is the target
Sodium K ATPase
17. Epithelial cells
Gag on pure gold
step two of RNA processing
The only histone not on the core
cytokeratin
18. Commonly results in dramatic decrease in amount of gene transcribed
silent mutation
Promoter mutation
dyenin
Alternate splicing
19. Less condensed - transciptionally active=eu truly transcobed
capped and tail transcript is called
Cell cycle
Pyrimidines
Euchromatin
20. Activated by GTP hydrolosis initiation factors help assembel the 40 S ribosomal subunites with the initiatior tRNA and are released whent he mRNA and the ribosomal subunit assemple with the complex
pyrimadines
Protein synthesis initiation
Which end of the tRNA is the amino acid bound to?
Tetracyclines
21. DNA And RNA synthesized in the 5-3 direction
Which is the most and least abundant type of RNA
DNA ligase
DNA/RNA/Protein syntesis direction
Thymine has a
22. Must be both activated and inactivated for cell cycle to progress
desmin
Tetracyclines
Cyclin - CDK
Step Three of RNA processing
23. Enter G1 from G0 when stimulated Hepatocytes/lymphocytes
Non homologous end joining
Griseofulvin
Stable (quiescent)
AUG codes For what in prokaryotes
24. Anti cancer - act on microtubules
Stable (quiescent)
Vincristine/Vinblastine
Collagen
Euchromatin
25. Hydroxy proline and hydroxylysine
Hydroxylation of which amino acids are attached to Glycine to form collagen
Loading tRNA on to ribosome energy requirement
Aminoglycosides
Promoter mutation
26. Neurons
Cyclins
Neurofilaments
nucleosid
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
27. More than 1 codon may code for the same amino acid
degenerate or redundant
single stranded binding proteinds
Prokaryotes
Silencer
28. Particular sequnece in genomre where DNA replication begins. May be single (prokaryotes) or multiple (eukaryotes)
helicase
origin of replication
Loading tRNA on to ribosome energy requirement
Covalent alterations
29. Site where RNA polymerase and multiple other transciption factors bind to DNA upstream from gene locus (AT rich upstream sequence with TATA and CAAT boxes)
Cyclins
promoter
tRNA Structure
Silencer
30. Exocytose procollagen into extracellylar sace
Example of permanent cells
Elongation
Excocytosis of collagen
desmin
31. Greater melting temperature lower fluidity
Guanine has a
Single Strand DNA Repair types
Higher the cholesterol or long saturated fatty acid content
Clindamycin
32. Read froma fixed starting point as a continous sequenecs of bases
commaless - non - overlapping
Primase
DNA pol I
DNA pol III
33. Base+ribose+phosphate linked by a phosphodiester bond
Elastin
promoter
DNA ligase
nucleotide
34. Y shaped region along DNA template where leading and lagging strands are syntehsized
Replication fork
Paclitaxil
Plasma membrane composition
Cyclin - CDK
35. Cleave terminal regions of procollagen to transform into insoluable tropocolagen
silent mutation
Xeroderma pigmentosum
Outside the cell what processing must be done in procolalgen
Loading tRNA on to ribosome energy requirement
36. Never go to Go divide rapidly with short G1 bone marrow - gut epithelium - skin - hair follicles
Loading tRNA on to ribosome energy requirement
Osteogenesis Imperfecta
DNA/RNA/Protein syntesis direction
Labile
37. Unmethylated - newly synthesized string is recognized - mismatched nucleotides are removed and the gap is filled and resealed
transition
pyrimadines
Mismatch repair
Post - translational modifications
38. Trimming removal of n or c terminal propeptides from zymogens to generate mature proteinds
Collagen
Protein synthesis initiation
Post - translational modifications
Cyclin - CDK
39. Even 40S 60S =80S
Fluoroquinolones
Associations of Ehlers Danlos
Eukaroytes
chromatin structure
40. Hn RNA
Paclitaxil
C- G bond
Initial transcript without processing is known as
mRNA is syntehsized in which direction?
41. Each codon specifies only 1 amino acid
Steps in splicing
Aminoglycosides
Higher the cholesterol or long saturated fatty acid content
unambiguous
42. Bind 50S blocking translocation
Post - translational modifications
Macrolides
Single Strand DNA Repair types
Collagen
43. Does not
Common amino acids in elastin
Neurofilaments
polyadenylation does/does not require a template
step two of RNA processing
44. Scrutinizes aa before and after it binds to tRNA. If incorrect bond is hydrolyzed.
Neurofilaments
Hydroxylation of which amino acids are attached to Glycine to form collagen
Aminoacylt - tRNA synthetase
In eukaryotes the starting amino acid is...
45. Inhibits ribonucleotide reductase
Going APE
Fluoroquinolones
mRNA start codons
hydroxyurea
46. Uracil
Post - translational modifications
Deamination of cytosine makes
step two of RNA processing
Pyrimidines
47. Tansport cellular cargo toward opposite ends of microtubule tracks
In eukaryotes the starting amino acid is...
Enhancers and silencer may be located_____
hydroxyurea
Molecular motor protiesn
48. Aminoacyl - tRNA binds to A site 2) peptidyltransferase catalyzes peptide bond formation transfers growing polypeptie to amino acid in A site 3) ribosome advances 3 nucleotides toward the 3 prime end of RNA moving peptiydyl RNA to P site
Elongation
kinesin
Excocytosis of collagen
Introns
49. Negatively charged DNA loops twice around histone octamers create a nucloesome bead.
What does the hydroxylation of proline and lysine require
AUG codes For what in prokaryotes
chromatin structure
capped and tail transcript is called
50. Ribonucleotide reductase
frame shift
dyenin
Termination
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by