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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Anit helminth - act on microtubules
What does the hydroxylation of proline and lysine require
Type IV collagen is an important structural component of...
Which end of the tRNA is the amino acid bound to?
Mebendazole/thiabendazole
2. Inhibits ribonucleotide reductase
pyrimadines
Aminoacylt - tRNA synthetase
hydroxyurea
Aminoglycosides
3. H1 string
Promoter mutation
Stable (quiescent)
Oubain
What ties teh nucleosome together
4. Connective tissue
commaless - non - overlapping
Heterochromatin
DNA ligase
Immunohistochemical stains vimentin
5. P53 and RB normally inhibit g1 to S progression
Tropocollagen cross links between_____ to form____
Rough ER
Tumor Suppressors
Deamination of cytosine makes
6. Enter G1 from G0 when stimulated Hepatocytes/lymphocytes
What type of collagen is most affected in Ehlers Danlos
Cyclin - CDK
Stable (quiescent)
Mismatch repair
7. Anterograde to microtubule
Silencer
kinesin
Enhancers and silencer may be located_____
Stable (quiescent)
8. Microvilli - muscle contraction - cytokinesis - adhering juntions
actin and myosin
DNA ligase
Alports syndrome
unambiguous
9. 2 H bonds greater GC content greater melting point
A- T
mRNA stop codons
Elongation
transversion
10. Muscle
Chloramphenicol
Methotrexate
desmin
step two of RNA processing
11. Checkpoints control transition between phases of cell cycle. regulated by cyclins - CDKs and tumor suppressors. Mitosis (shortest phse)
AUG codes For what in prokaryotes
hydroxyurea
intermediate filaments
Cell cycle
12. RER translation of collagen alpha chains (preprocollagen) usually Gly-X-Y
Nucleotide excision repair
Single Strand DNA Repair types
Guanine has a
Collagedn synthesis where?
13. Cyclin depndent kinases; consituative and inactive
CDKs
Translocation
silent mutation
pyrimadines
14. Inhibits dihydrofolate reductase down thymine
Promoter mutation
Euchromatin
DNA pol I
Methotrexate
15. Codes for formyl methionine (f - Met)
AUG codes For what in prokaryotes
What does the hydroxylation of proline and lysine require
Sodium K ATPase
Mebendazole/thiabendazole
16. Cylindrical structure composed of helical array of plymerized dimers of alpha and beta tubulin - flagella - cilia - mitotic spindle - grows slowly collapses quickly
microtubule
Loading tRNA on to ribosome energy requirement
Going APE
Type IV collagen is an important structural component of...
17. Inhibit DNA gyrase (specific prokaryotic topoisomerase)
tRNA aminoacylation
Gag on pure gold
Fluoroquinolones
RNA processing in eukaryotes occurs
18. Inhibits by binding to the potassium side
Paclitaxil
Oubain
Type IV collagen is an important structural component of...
Ehlers Danlos
19. Must be both activated and inactivated for cell cycle to progress
Cilia structure
Heterochromatin
Hydroxylation of which amino acids are attached to Glycine to form collagen
Cyclin - CDK
20. Cleave terminal regions of procollagen to transform into insoluable tropocolagen
Outside the cell what processing must be done in procolalgen
Initial transcript without processing is known as
Common amino acids in elastin
nucleotide
21. Makes an RNA primer on which DNA polymerase II can initiate replication
transversion
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
degenerate or redundant
Primase
22. Blocks denovo purine synthesis
nucleotide
6MP
Permanent cells
hydroxyurea
23. Negatively charged DNA loops twice around histone octamers create a nucloesome bead.
chromatin structure
Tetracyclines
silent mutation
6MP
24. Create a nick in the helix to relieve supercoils created during replication
step two of RNA processing
degenerate or redundant
Free ribosomes
DNA topoisomerases
25. Vimentin - desmin - cytockeratin - glial fibrillary acid proteins - neurofilaments
Aminoglycosides
Rough ER
Digoxin (cardiac glycosides)
intermediate filaments
26. Has enough energy to created the peptide bond
Excocytosis of collagen
Cilia structure
purines
the tRNA- amino acid bond
27. Capping on 5 prime end (7 methylguanosine) -
Functional organization of the gene
Step one of RNA processing
cytokeratin
Xeroderma pigmentosum
28. Attachment of ubiquitin to defective proteinds to tag them for breakdown
Proteosomal degradation
Nucleotide excision repair
Silencer
Axonemal dyenin
29. Accurate base pairing is required only in the first 2 nucleotide positions of an mRNA so codons differing ht e3rd wobble psoition may code for the same tRNA/amino acid code
tRNA
Tropocollagen cross links between_____ to form____
Clindamycin
In eukaryotes the starting amino acid is...
30. Base+ribose+phosphate linked by a phosphodiester bond
Clindamycin
nucleotide
silent mutation
nucleosid
31. RNA polymerase I makes rRNA - RNA pol II makes mRNA - RNA pol III makes tRNA
Aminoglycosides
RNA polymerases in eukaryotes
methionine is only encoded by
Silencer
32. Particular sequnece in genomre where DNA replication begins. May be single (prokaryotes) or multiple (eukaryotes)
Cholchicine
Cilia structure
Sodium K ATPase
origin of replication
33. A malfunction of mismatch repair (MUt L etc..)
Hereditary non polyposis colorectal cancer
Enhancers and silencer may be located_____
Nucleotide excision repair
silent mutation
34. Be So Totatally Cool Read Books (bOne - CarTWOlage - Threeticular - Type IV under the floor)
Which end of the tRNA is the amino acid bound to?
Cholchicine
Collagen
Termination
35. Close to - far from or even within (in an intron) the gene whose expression it regulates
What ties teh nucleosome together
Paclitaxil
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
Enhancers and silencer may be located_____
36. Completed protein is released from ribosme through simple hydrolosis and dissociates
Primase
actin and myosin
Alports syndrome
Termination
37. Even 40S 60S =80S
Total energy expenditure requirement for translocation
In eukaryotes the starting amino acid is...
Collagen
Eukaroytes
38. You glyucosolate hte pro - alpha chain lysine resudens and form procollagen (triple helix of alpha chains)
Glycosolation
RNA polymerases in eukaryotes
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
Covalent alterations
39. CCA AT 3 PRIME END
White codon is at the 3 prime end of a tRNA
Single Strand DNA Repair types
Elastin is broken down by
Silencer
40. Less condensed - transciptionally active=eu truly transcobed
Associations of Ehlers Danlos
Type IV collagen is an important structural component of...
A- T
Euchromatin
41. Methyl THYmine has a meTHYl
tRNA aminoacylation
mRNA start codons
Sodium K ATPase
Thymine has a
42. One codon AUG
methionine is only encoded by
Tumor Suppressors
White codon is at the 3 prime end of a tRNA
Where do introns and exons stay
43. Substituting a purine for a pyrimdine or vice versa
Molecular motor protiesn
What type of collagen is most affected in Ehlers Danlos
transversion
Exons
44. Commonly results in dramatic decrease in amount of gene transcribed
Promoter mutation
chromatin structure
Functional organization of the gene
Osteogenesis Imperfecta
45. Site where RNA polymerase and multiple other transciption factors bind to DNA upstream from gene locus (AT rich upstream sequence with TATA and CAAT boxes)
Cyclin - CDK
Total energy expenditure requirement for translocation
promoter
DNA pol I
46. No proofreading function but can initiate chains. RNA poymerase II opens DNA at promoter site
Aminoglycosides
helicase
Proofreading function in eukaryotic RNA
transition
47. A site - incoming aminoacyl tRNA - Psite accomodates growing Peptide - E site holds EmplytRNA as it exits
alpha amintin
Enhancers and silencer may be located_____
Free ribosomes
Going APE
48. Introns stay In the nucleus whereas EXons EXit and are EXpressed
Proofreading function in eukaryotic RNA
polyadenylation does/does not require a template
Heterochromatin
Where do introns and exons stay
49. Aminoacyl - tRNA binds to A site 2) peptidyltransferase catalyzes peptide bond formation transfers growing polypeptie to amino acid in A site 3) ribosome advances 3 nucleotides toward the 3 prime end of RNA moving peptiydyl RNA to P site
C- G bond
Deamination of cytosine makes
Enhancer
Elongation
50. Faulty collagen synthesis causing 1) hyperextensible skin 2) tendency to bleed 3) hypermobile joints
Pyrimidines
Ehlers Danlos
Sodium K ATPase
Fluoroquinolones