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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Xlinked recessive IV collagen bm - kidney - ear and eye -- nephritis and defness ocular disturbances
Clindamycin
Xeroderma pigmentosum
single stranded binding proteinds
Alports syndrome
2. Odd 30S plus 50 S=70S
Stable (quiescent)
Prokaryotes
Exons
Step Three of RNA processing
3. Inhibit formation of the initation complex and cause misreading of mRNA
Cilia structure
trimethoprim
Aminoglycosides
Higher the cholesterol or long saturated fatty acid content
4. Greater melting temperature lower fluidity
Which end of the nucleotide has the triphosphate
missense mutation
Higher the cholesterol or long saturated fatty acid content
6MP
5. ATP
Protein synthesis is in which direction
tRNA activation
Mismatch repair
Covalent alterations
6. Condensed - transciptionally inactive HC- Highly condensed
Heterochromatin
Cell cycle order
GFAP
Neurofilaments
7. The 5prime end (energy for the bond)
Which end of the nucleotide has the triphosphate
commaless - non - overlapping
actin and myosin
purines
8. Blocks denovo purine synthesis
6MP
Promoter mutation
Double Strand DNA repair
Mismatch repair
9. Connective tissue
Fluoroquinolones
Elongation
Immunohistochemical stains vimentin
Type IV collagen is an important structural component of...
10. RNA polymerase I makes rRNA - RNA pol II makes mRNA - RNA pol III makes tRNA
Axonemal dyenin
Guanine has a
Elastase is inhibited by
RNA polymerases in eukaryotes
11. Hn RNA
missense mutation
Molecular motor protiesn
Initial transcript without processing is known as
CDKs
12. H1
The only histone not on the core
intermediate filaments
Permanent cells
missense mutation
13. RER translation of collagen alpha chains (preprocollagen) usually Gly-X-Y
Collagedn synthesis where?
nucleotide
Elastin is broken down by
Hydroxylation of which amino acids are attached to Glycine to form collagen
14. Inhibits dihydrofolate reductase down thymine
pyrimadines
Exons
Steps in splicing
Methotrexate
15. Retrograde to microtubules
Griseofulvin
dyenin
unambiguous
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
16. GTP
Clindamycin
Collagen
tRNA gripping and going places
nonsense
17. Inhibits ribonucleotide reductase
microtubule
Silencer
Chloramphenicol
hydroxyurea
18. Trimming removal of n or c terminal propeptides from zymogens to generate mature proteinds
alpha amintin
Post - translational modifications
Protein synthesis initiation
mRNA is syntehsized in which direction?
19. Muscle
Elongation
desmin
Protein synthesis initiation
Which end of a growing DNA strand is the target
20. Genetic bone disorder (brittle bone disease) type 1 colalgen - fractures (during birth) 2) Blue sclerae 3) hearing loss 4) dental imperfections 1:10000 may be confused with child abuse
Osteogenesis Imperfecta
Associations of Ehlers Danlos
Free ribosomes
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
21. Particular sequnece in genomre where DNA replication begins. May be single (prokaryotes) or multiple (eukaryotes)
White codon is at the 3 prime end of a tRNA
Aminoacylt - tRNA synthetase
origin of replication
Deamination of cytosine makes
22. Three amino acids necessary for purine synthesis= glutamine - aspartate and glycine
Gag on pure gold
nonsense
A- T
What type of collagen is most affected in Ehlers Danlos
23. Strethchy protein within lungs - large artiers - elastic liaments - vocal cords - ligamenta flava)
Translocation
Elastin
Type IV collagen is an important structural component of...
Associations of Ehlers Danlos
24. Immotile cilia due to a dyenin arm defect. Results in male nad female inferticility (sperm immotile) - bronchiectasis - and recurrent sinusisits - associated with situs inversus
Kartageners syndrome
Tumor Suppressors
White codon is at the 3 prime end of a tRNA
Free ribosomes
25. Close to - far from or even within (in an intron) the gene whose expression it regulates
Vincristine/Vinblastine
single stranded binding proteinds
Euchromatin
Enhancers and silencer may be located_____
26. Elastase
Primase
alpha amintin
Elastin is broken down by
Cell cycle
27. Type III
Thymine has a
mRNA start codons
What type of collagen is most affected in Ehlers Danlos
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
28. Base+ribose+phosphate linked by a phosphodiester bond
helicase
nucleotide
Step Three of RNA processing
histone octamer names
29. Unmethylated - newly synthesized string is recognized - mismatched nucleotides are removed and the gap is filled and resealed
Mismatch repair
Protein synthesis is in which direction
Collagen
purines
30. The 3 prime end
Which end of the tRNA is the amino acid bound to?
Aminoacylt - tRNA synthetase
Mebendazole/thiabendazole
Chloramphenicol
31. Be So Totatally Cool Read Books (bOne - CarTWOlage - Threeticular - Type IV under the floor)
degenerate or redundant
Guanine has a
DNA ligase
Collagen
32. Capping on 5 prime end (7 methylguanosine) -
DNA topoisomerases
Thymine has a
Nucleotide excision repair
Step one of RNA processing
33. Anti breast cancer - acts on mts
Replication fork
Cyclin - CDK
Tetracyclines
Paclitaxil
34. CUT 1 ring Cut the Py
Aminoglycosides
Pyrimidines
pyrimadines
Higher the cholesterol or long saturated fatty acid content
35. Activated by GTP hydrolosis initiation factors help assembel the 40 S ribosomal subunites with the initiatior tRNA and are released whent he mRNA and the ribosomal subunit assemple with the complex
Heterochromatin
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
Protein synthesis initiation
chromatin structure
36. Substituting a pyramidine for a pyrimadine
transition
Where do introns and exons stay
Ehlers Danlos
In eukaryotes the starting amino acid is...
37. Contain the actual genetic information coding for protein
Type IV collagen is an important structural component of...
Macrolides
Exons
transversion
38. Cyclin depndent kinases; consituative and inactive
CDKs
Promoter mutation
Sodium K ATPase
Step Three of RNA processing
39. Methyl THYmine has a meTHYl
Going APE
5FU
Translocation
Thymine has a
40. Attachment of ubiquitin to defective proteinds to tag them for breakdown
In eukaryotes the starting amino acid is...
Collagedn synthesis where?
Double Strand DNA repair
Proteosomal degradation
41. 1) primary transcript combines with snRNPs and other proteins to form spliceosome 2) lariat shaped intermediate is generated 3) Lariat is removed and released to precisely join 2 exons
Enhancer
Excocytosis of collagen
Osteogenesis Imperfecta
Steps in splicing
42. Seals
Permanent cells
Outside the cell what processing must be done in procolalgen
DNA ligase
Tetracyclines
43. Site of dteroid synthesis and detoxification of druigs and poisons (liver hepatocytes and steroid horomore adrenal cortex)
Smooth ER
Guanine has a
tRNA activation
alpha amintin
44. Completed protein is released from ribosme through simple hydrolosis and dissociates
Glycosolation
Termination
Prokaryote RNA pol
Free ribosomes
45. Checkpoints control transition between phases of cell cycle. regulated by cyclins - CDKs and tumor suppressors. Mitosis (shortest phse)
Mebendazole/thiabendazole
Which end of a growing DNA strand is the target
What ties teh nucleosome together
Cell cycle
46. UGA - UAG - UAA
Aminoglycosides
Tetracyclines
Loading tRNA on to ribosome energy requirement
mRNA stop codons
47. 5 prime to 3 prime
Oubain
mRNA stop codons
mRNA is syntehsized in which direction?
Which is the most and least abundant type of RNA
48. The 3 prime hydroxyl of the nascent chain is the target
Plasma membrane composition
Which end of a growing DNA strand is the target
Neurofilaments
RNA polymerases in eukaryotes
49. ATP- AMP (2 phosphoanhydride bonds)
Cell cycle
mRNA start codons
tRNA aminoacylation
Tumor Suppressors
50. Remain in G0 regenerate from stem cells
Example of permanent cells
Stable (quiescent)
Labile
Permanent cells