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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Does not
Protein synthesis initiation
DNA topoisomerases
Prokaryote RNA pol
polyadenylation does/does not require a template
2. Hydroxy proline and hydroxylysine
hydroxyurea
Hydroxylation of which amino acids are attached to Glycine to form collagen
Vincristine/Vinblastine
Paclitaxil
3. Condensed - transciptionally inactive HC- Highly condensed
Heterochromatin
Higher the cholesterol or long saturated fatty acid content
Macrolides
Permanent cells
4. Introns stay In the nucleus whereas EXons EXit and are EXpressed
In eukaryotes the starting amino acid is...
Guanine has a
Osteogenesis Imperfecta
Where do introns and exons stay
5. Inhibit DNA gyrase (specific prokaryotic topoisomerase)
microtubule
DNA ligase
Fluoroquinolones
Type IV collagen is an important structural component of...
6. Microtubule polymerization defect resulting in lowered phagocytosis. results in recurrent pyogenic infections - partial albinism and peripheral neuropathy
Osteogenesis Imperfecta
Cholchicine
Chediak Higashi syndrome
Griseofulvin
7. Muscle
In eukaryotes the starting amino acid is...
Guanine has a
desmin
Mebendazole/thiabendazole
8. HS1 - HSB - H2 - H4
Gag on pure gold
Molecular motor protiesn
histone octamer names
actin and myosin
9. Inhibit formation of the initation complex and cause misreading of mRNA
pyrimadines
The only histone not on the core
Aminoglycosides
What does the hydroxylation of proline and lysine require
10. Tansport cellular cargo toward opposite ends of microtubule tracks
Tropocollagen cross links between_____ to form____
Fluoroquinolones
Molecular motor protiesn
Protein synthesis initiation
11. Less condensed - transciptionally active=eu truly transcobed
mRNA start codons
Euchromatin
Double Strand DNA repair
Alternate splicing
12. Lysine/hydroxylysine and combines to form collagen
Tropocollagen cross links between_____ to form____
White codon is at the 3 prime end of a tRNA
tRNA activation
DNA topoisomerases
13. In the nucleus after transcitpion and only processed RNA is transporte out of the nucleus
5FU
RNA processing in eukaryotes occurs
Macrolides
Silencer
14. Alpha 1 antitrypisn
White codon is at the 3 prime end of a tRNA
Elastase is inhibited by
Non homologous end joining
Plasma membrane composition
15. Site of dteroid synthesis and detoxification of druigs and poisons (liver hepatocytes and steroid horomore adrenal cortex)
nucleosid
Post - translational modifications
Smooth ER
Thymine has a
16. Brings together 2 ends of DNA fragments no requirement for homology
capped and tail transcript is called
Non homologous end joining
Alports syndrome
methionine is only encoded by
17. Antigout - acts on mts
Which end of the nucleotide has the triphosphate
Kartageners syndrome
Cholchicine
Paclitaxil
18. ATP- AMP (2 phosphoanhydride bonds)
universal
tRNA aminoacylation
DNA pol III
Example of permanent cells
19. Substituting a pyramidine for a pyrimadine
Neurofilaments
transition
White codon is at the 3 prime end of a tRNA
Tumor Suppressors
20. 1P (blocked by tetracycline)
Which is the most and least abundant type of RNA
Translocation
Loading tRNA on to ribosome energy requirement
Exons
21. 2 H bonds greater GC content greater melting point
Fluoroquinolones
A- T
Methotrexate
Vincristine/Vinblastine
22. Particular sequnece in genomre where DNA replication begins. May be single (prokaryotes) or multiple (eukaryotes)
origin of replication
Which end of a growing DNA strand is the target
Elastin is broken down by
Fluoroquinolones
23. Attachment of ubiquitin to defective proteinds to tag them for breakdown
DNA/RNA/Protein syntesis direction
Proteosomal degradation
Collagen
nucleosid
24. Negatively charged DNA loops twice around histone octamers create a nucloesome bead.
chromatin structure
methionine is only encoded by
Promoter mutation
helicase
25. Faulty collagen synthesis causing 1) hyperextensible skin 2) tendency to bleed 3) hypermobile joints
Ehlers Danlos
degenerate or redundant
frame shift
RNA polymerases in eukaryotes
26. The 3 prime end
silent mutation
What does the hydroxylation of proline and lysine require
Loading tRNA on to ribosome energy requirement
Which end of the tRNA is the amino acid bound to?
27. Methionine - which may be removed before translation is completed
Protein synthesis initiation
Kartageners syndrome
In eukaryotes the starting amino acid is...
Elastase is inhibited by
28. Prophas - metaphase - anaphase telophase
Example of permanent cells
Vincristine/Vinblastine
Where do introns and exons stay
Order of mitosis
29. Anti breast cancer - acts on mts
In eukaryotes the starting amino acid is...
Which is the most and least abundant type of RNA
mRNA start codons
Paclitaxil
30. Scrutinizes aa before and after it binds to tRNA. If incorrect bond is hydrolyzed.
methionine is only encoded by
Elongation
Aminoacylt - tRNA synthetase
Step one of RNA processing
31. Contain the actual genetic information coding for protein
mRNA stop codons
Exons
6MP
Purines
32. ATP
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
Which end of a growing DNA strand is the target
Where do introns and exons stay
tRNA activation
33. 1 RNA polymerase (multisubunite complex) makes all 3 kinds of RNA
Prokaryote RNA pol
Enhancers and silencer may be located_____
Stable (quiescent)
transition
34. Enter G1 from G0 when stimulated Hepatocytes/lymphocytes
Exons
cytokeratin
Promoter mutation
Stable (quiescent)
35. Immotile cilia due to a dyenin arm defect. Results in male nad female inferticility (sperm immotile) - bronchiectasis - and recurrent sinusisits - associated with situs inversus
alpha amintin
Osteogenesis Imperfecta
Kartageners syndrome
tRNA
36. Activated by GTP hydrolosis initiation factors help assembel the 40 S ribosomal subunites with the initiatior tRNA and are released whent he mRNA and the ribosomal subunit assemple with the complex
Which end of a growing DNA strand is the target
Primase
Protein synthesis initiation
Common amino acids in elastin
37. Cylindrical structure composed of helical array of plymerized dimers of alpha and beta tubulin - flagella - cilia - mitotic spindle - grows slowly collapses quickly
Base excision repair
microtubule
Prokaryotes
Plasma membrane composition
38. Anti cancer - act on microtubules
Vincristine/Vinblastine
pyrimadines
Aminoglycosides
Single Strand DNA Repair types
39. Prokaryotic only. Degrades RNA primer and fills in the gap with DNA (5 prime to 3 prime exonuclease)
Cell cycle order
Translocation
DNA pol I
Step Three of RNA processing
40. CUT 1 ring Cut the Py
RNA polymerases in eukaryotes
Non homologous end joining
frame shift
Pyrimidines
41. 1P blocked by chloramphenicaol and macrolide
nucleotide
microtubule
Euchromatin
Translocation
42. Remain in G0 regenerate from stem cells
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
Permanent cells
Plasma membrane composition
Guanine has a
43. (A - G) 2 rings Pure As Gold
Cell cycle order
Heterochromatin
mRNA stop codons
Purines
44. Hn RNA
Double Strand DNA repair
Initial transcript without processing is known as
Clindamycin
Ehlers Danlos
45. Change resulting in early stop codon
kinesin
Cell cycle order
helicase
nonsense
46. Splicing out of introns
transition
Alternate splicing
Step Three of RNA processing
Loading tRNA on to ribosome energy requirement
47. Prevents stranges from reannealing
Post - translational modifications
AUG codes For what in prokaryotes
single stranded binding proteinds
Where do introns and exons stay
48. Phosphorylation - glycosloation - hyderoxylation
Which is the most and least abundant type of RNA
Covalent alterations
Protein synthesis initiation
Base excision repair
49. Antifungal - act on microtubules
Type IV collagen is an important structural component of...
missense mutation
nucleosid
Griseofulvin
50. P53 and RB normally inhibit g1 to S progression
mRNA start codons
Tumor Suppressors
universal
RNA polymerases in eukaryotes