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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Inhibits 50S peptidyl transferase
mRNA start codons
RNA processing in eukaryotes occurs
Chloramphenicol
Xeroderma pigmentosum
2. Prophas - metaphase - anaphase telophase
unambiguous
Functional organization of the gene
White codon is at the 3 prime end of a tRNA
Order of mitosis
3. 3 sodium out for 2 potassium in (nout - kin)takes 1 atp and the machine is phosphorylated during the machine cycle
Sodium K ATPase
DNA topoisomerases
microtubule
frame shift
4. Made from IMP precursor
Step Three of RNA processing
Single Strand DNA Repair types
origin of replication
purines
5. Non homologous end joining
frame shift
Smooth ER
Immunohistochemical stains vimentin
Double Strand DNA repair
6. Neurons
What ties teh nucleosome together
Neurofilaments
intermediate filaments
What type of collagen is most affected in Ehlers Danlos
7. Microtubule polymerization defect resulting in lowered phagocytosis. results in recurrent pyogenic infections - partial albinism and peripheral neuropathy
transition
Chediak Higashi syndrome
hydroxyurea
Outside the cell what processing must be done in procolalgen
8. Neurons - skeletal - and cardiac muscle - RBCs
commaless - non - overlapping
Prokaryotes
Example of permanent cells
actin and myosin
9. Elastase
Elastin is broken down by
Hereditary non polyposis colorectal cancer
Proofreading function in eukaryotic RNA
Pyrimidines
10. Three amino acids necessary for purine synthesis= glutamine - aspartate and glycine
C- G bond
Free ribosomes
Gag on pure gold
kinesin
11. Exocytose procollagen into extracellylar sace
Which end of the nucleotide has the triphosphate
Excocytosis of collagen
cytokeratin
universal
12. Tansport cellular cargo toward opposite ends of microtubule tracks
Where do introns and exons stay
What does the hydroxylation of proline and lysine require
Molecular motor protiesn
Higher the cholesterol or long saturated fatty acid content
13. Read froma fixed starting point as a continous sequenecs of bases
Hereditary non polyposis colorectal cancer
Elongation
nucleotide
commaless - non - overlapping
14. Substituting a purine for a pyrimdine or vice versa
transversion
Introns
Covalent alterations
DNA/RNA/Protein syntesis direction
15. Commonly results in dramatic decrease in amount of gene transcribed
Plasma membrane composition
Promoter mutation
AUG codes For what in prokaryotes
Axonemal dyenin
16. Base+ribose+phosphate linked by a phosphodiester bond
Proteosomal degradation
tRNA aminoacylation
nucleotide
Free ribosomes
17. Greater melting temperature lower fluidity
Higher the cholesterol or long saturated fatty acid content
tRNA aminoacylation
Cyclin - CDK
Prokaryotes
18. CUT 1 ring Cut the Py
Pyrimidines
step two of RNA processing
Elastase is inhibited by
In eukaryotes the starting amino acid is...
19. Uracil
Deamination of cytosine makes
Initial transcript without processing is known as
Which end of the nucleotide has the triphosphate
Free ribosomes
20. Site of secretory protiens (mucus secreting goblet cells and antibody secreting cells)
Covalent alterations
C- G bond
Rough ER
The only histone not on the core
21. 3 H bonds
Where do introns and exons stay
C- G bond
Silencer
Heterochromatin
22. Cleave terminal regions of procollagen to transform into insoluable tropocolagen
Euchromatin
Cell cycle
Osteogenesis Imperfecta
Outside the cell what processing must be done in procolalgen
23. Remain in G0 regenerate from stem cells
Permanent cells
Immunohistochemical stains vimentin
silent mutation
Termination
24. Responsible for the accuracy of amino acid selection
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
GFAP
Tumor Suppressors
In eukaryotes the starting amino acid is...
25. Changed aaconservative - new aa is similar in chemical structure
GFAP
missense mutation
Stable (quiescent)
chromatin structure
26. Methionine - which may be removed before translation is completed
Base excision repair
In eukaryotes the starting amino acid is...
nonsense
Going APE
27. One codon AUG
methionine is only encoded by
DNA ligase
Where do introns and exons stay
microtubule
28. No proofreading function but can initiate chains. RNA poymerase II opens DNA at promoter site
DNA pol III
Proofreading function in eukaryotic RNA
kinesin
Oubain
29. Change resulting in misreading of all nucleotides downstream - usually resulting in a truncated non functional protien
frame shift
Example of permanent cells
Cyclin - CDK
mRNA stop codons
30. Negatively charged DNA loops twice around histone octamers create a nucloesome bead.
chromatin structure
C- G bond
Replication fork
Methotrexate
31. Prokaryotic only. Elongates leading strand by adding deoxynucleotides to the 3prime end. Elongates laggin strand. 3 prime to 5 prime exonuclease activity
DNA pol III
Stable (quiescent)
Plasma membrane composition
degenerate or redundant
32. Contain the actual genetic information coding for protein
Exons
Where do introns and exons stay
desmin
actin and myosin
33. Splicing out of introns
single stranded binding proteinds
Which end of the tRNA is the amino acid bound to?
Step Three of RNA processing
Protein synthesis is in which direction
34. Genetic bone disorder (brittle bone disease) type 1 colalgen - fractures (during birth) 2) Blue sclerae 3) hearing loss 4) dental imperfections 1:10000 may be confused with child abuse
Osteogenesis Imperfecta
Cholchicine
6MP
Methotrexate
35. Aminoacyl - tRNA binds to A site 2) peptidyltransferase catalyzes peptide bond formation transfers growing polypeptie to amino acid in A site 3) ribosome advances 3 nucleotides toward the 3 prime end of RNA moving peptiydyl RNA to P site
silent mutation
Alternate splicing
Elongation
DNA topoisomerases
36. Site where RNA polymerase and multiple other transciption factors bind to DNA upstream from gene locus (AT rich upstream sequence with TATA and CAAT boxes)
Associations of Ehlers Danlos
promoter
Chloramphenicol
Smooth ER
37. G1 - S - G2 - Mitosis
Cell cycle order
Enhancers and silencer may be located_____
Tetracyclines
transition
38. Scrutinizes aa before and after it binds to tRNA. If incorrect bond is hydrolyzed.
frame shift
Cell cycle
Aminoacylt - tRNA synthetase
hydroxyurea
39. Anti breast cancer - acts on mts
helicase
Elastase is inhibited by
Paclitaxil
Excocytosis of collagen
40. Ribonucleotide reductase
Tetracyclines
Smooth ER
Which is the most and least abundant type of RNA
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
41. Hn RNA
unambiguous
Macrolides
What does the hydroxylation of proline and lysine require
Initial transcript without processing is known as
42. Muscle
Where do introns and exons stay
desmin
helicase
RNA polymerases in eukaryotes
43. Poly adenylation
DNA ligase
Elastase is inhibited by
Smooth ER
step two of RNA processing
44. More than 1 codon may code for the same amino acid
Introns
Fluoroquinolones
degenerate or redundant
Order of mitosis
45. Specific endonucleases release the oligonucleotide containing damaged bases. DNA polymerase and logase fill and resealt eh gap
Nucleotide excision repair
Chloramphenicol
single stranded binding proteinds
Enhancers and silencer may be located_____
46. Proline - glycine
Common amino acids in elastin
Sodium K ATPase
DNA pol III
Hydroxylation of which amino acids are attached to Glycine to form collagen
47. 2 H bonds greater GC content greater melting point
Smooth ER
Elastase is inhibited by
purines
A- T
48. Particular sequnece in genomre where DNA replication begins. May be single (prokaryotes) or multiple (eukaryotes)
Cyclin - CDK
Single Strand DNA Repair types
origin of replication
Free ribosomes
49. Be So Totatally Cool Read Books (bOne - CarTWOlage - Threeticular - Type IV under the floor)
Which is the most and least abundant type of RNA
Plasma membrane composition
Collagen
the tRNA- amino acid bond
50. The N to C
Protein synthesis is in which direction
Xeroderma pigmentosum
Ehlers Danlos
Order of mitosis