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First Aid: Biochemistry Molecular

Subjects : health-sciences, first-aid

Instructions:

Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can study here.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Changed aaconservative - new aa is similar in chemical structure
Sodium K ATPase
Gag on pure gold
missense mutation
Deamination of cytosine makes

2. ATP ase that links peripheral 9 doublets and causes bending of cilium by differential sliding of doublets
Double Strand DNA repair
Axonemal dyenin
Which is the most and least abundant type of RNA
Elastin is broken down by

3. H1
The only histone not on the core
Cell cycle order
origin of replication
Which end of a growing DNA strand is the target

4. Inhibit formation of the initation complex and cause misreading of mRNA
Aminoglycosides
Tumor Suppressors
step two of RNA processing
What ties teh nucleosome together

5. Bind 50S blocking translocation
Macrolides
actin and myosin
origin of replication
What ties teh nucleosome together

6. Type III
Cholchicine
What type of collagen is most affected in Ehlers Danlos
Cilia structure
What does the hydroxylation of proline and lysine require

7. Exocytose procollagen into extracellylar sace
capped and tail transcript is called
Paclitaxil
Non homologous end joining
Excocytosis of collagen

8. VItamin C
purines
Free ribosomes
Silencer
What does the hydroxylation of proline and lysine require

9. Prokaryotic only. Degrades RNA primer and fills in the gap with DNA (5 prime to 3 prime exonuclease)
A- T
dyenin
DNA pol I
Glycosolation

10. Prokaryotic only. Elongates leading strand by adding deoxynucleotides to the 3prime end. Elongates laggin strand. 3 prime to 5 prime exonuclease activity
Sodium K ATPase
DNA pol III
What does the hydroxylation of proline and lysine require
universal

11. Y shaped region along DNA template where leading and lagging strands are syntehsized
Replication fork
Alternate splicing
Stable (quiescent)
Cell cycle order

12. 5 prime to 3 prime
mRNA is syntehsized in which direction?
Associations of Ehlers Danlos
Protein synthesis initiation
Chloramphenicol

13. Responsible for the accuracy of amino acid selection
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
helicase
microtubule
Elastase is inhibited by

14. Seals
Fluoroquinolones
DNA ligase
single stranded binding proteinds
Vincristine/Vinblastine

15. Base + ribose
Elastase is inhibited by
RNA processing in eukaryotes occurs
nucleosid
Axonemal dyenin

16. Promoter - enhancer - promoter - TATA- transcription initiation site - coding region (including exons and introns) and then the AATAAA
Functional organization of the gene
Where do introns and exons stay
Plasma membrane composition
tRNA Structure

17. Particular sequnece in genomre where DNA replication begins. May be single (prokaryotes) or multiple (eukaryotes)
origin of replication
What ties teh nucleosome together
purines
Which end of the tRNA is the amino acid bound to?

18. Tansport cellular cargo toward opposite ends of microtubule tracks
Mismatch repair
C- G bond
Molecular motor protiesn
Plasma membrane composition

19. Site where RNA polymerase and multiple other transciption factors bind to DNA upstream from gene locus (AT rich upstream sequence with TATA and CAAT boxes)
Steps in splicing
promoter
DNA pol III
Immunohistochemical stains vimentin

20. Immotile cilia due to a dyenin arm defect. Results in male nad female inferticility (sperm immotile) - bronchiectasis - and recurrent sinusisits - associated with situs inversus
CDKs
Kartageners syndrome
DNA ligase
Methotrexate

21. Antigout - acts on mts
Termination
Cyclins
Cholchicine
AUG codes For what in prokaryotes

22. Unwinds DNA template at replication fork
mRNA is syntehsized in which direction?
Alports syndrome
helicase
Smooth ER

23. Inhibits the atpase which increases intracellular sodium which increases intracellular calcium increases cardiaccontractility
Molecular motor protiesn
Elastin
Axonemal dyenin
Digoxin (cardiac glycosides)

24. Stretch of DNA that alters gene expression by binding transcription factors
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
Enhancer
Which end of the tRNA is the amino acid bound to?
tRNA aminoacylation

25. Be So Totatally Cool Read Books (bOne - CarTWOlage - Threeticular - Type IV under the floor)
Elongation
Mismatch repair
Which is the most and least abundant type of RNA
Collagen

26. Cyclin depndent kinases; consituative and inactive
CDKs
commaless - non - overlapping
Molecular motor protiesn
tRNA gripping and going places

27. Capping on 5 prime end (7 methylguanosine) -
Initial transcript without processing is known as
Step one of RNA processing
commaless - non - overlapping
AUG codes For what in prokaryotes

28. Unmethylated - newly synthesized string is recognized - mismatched nucleotides are removed and the gap is filled and resealed
the tRNA- amino acid bond
Where do introns and exons stay
RNA polymerases in eukaryotes
Mismatch repair

29. Close to - far from or even within (in an intron) the gene whose expression it regulates
Enhancers and silencer may be located_____
Outside the cell what processing must be done in procolalgen
Cyclins
Common amino acids in elastin

30. Anti breast cancer - acts on mts
mRNA stop codons
Functional organization of the gene
nucleosid
Paclitaxil

31. Retrograde to microtubules
dyenin
Prokaryotes
Hereditary non polyposis colorectal cancer
promoter

32. Brings together 2 ends of DNA fragments no requirement for homology
Chloramphenicol
Non homologous end joining
tRNA aminoacylation
Sodium K ATPase

33. DNA And RNA synthesized in the 5-3 direction
Cilia structure
commaless - non - overlapping
DNA/RNA/Protein syntesis direction
Which end of a growing DNA strand is the target

34. RNA polymerase I makes rRNA - RNA pol II makes mRNA - RNA pol III makes tRNA
capped and tail transcript is called
RNA polymerases in eukaryotes
Euchromatin
Cyclins

35. Elastase
Elastin is broken down by
tRNA
In eukaryotes the starting amino acid is...
Macrolides

36. Scrutinizes aa before and after it binds to tRNA. If incorrect bond is hydrolyzed.
Purines
Axonemal dyenin
Free ribosomes
Aminoacylt - tRNA synthetase

37. Odd 30S plus 50 S=70S
Cyclins
helicase
Exons
Prokaryotes

38. Microtubule polymerization defect resulting in lowered phagocytosis. results in recurrent pyogenic infections - partial albinism and peripheral neuropathy
Protein synthesis initiation
Chediak Higashi syndrome
Single Strand DNA Repair types
Stable (quiescent)

39. Faulty collagen synthesis causing 1) hyperextensible skin 2) tendency to bleed 3) hypermobile joints
Promoter mutation
Ehlers Danlos
kinesin
Covalent alterations

40. Attachment of ubiquitin to defective proteinds to tag them for breakdown
Free ribosomes
Translocation
Excocytosis of collagen
Proteosomal degradation

41. Trimming removal of n or c terminal propeptides from zymogens to generate mature proteinds
Which end of the tRNA is the amino acid bound to?
C- G bond
microtubule
Post - translational modifications

42. Genetic code is conserved throughout evolution
Glycosolation
tRNA
universal
histone octamer names

43. Hn RNA
trimethoprim
Griseofulvin
Initial transcript without processing is known as
Outside the cell what processing must be done in procolalgen

44. Poly adenylation
The only histone not on the core
Cyclins
step two of RNA processing
Mebendazole/thiabendazole

45. Activated by GTP hydrolosis initiation factors help assembel the 40 S ribosomal subunites with the initiatior tRNA and are released whent he mRNA and the ribosomal subunit assemple with the complex
Termination
Protein synthesis initiation
Proofreading function in eukaryotic RNA
Alports syndrome

46. Methionine - which may be removed before translation is completed
Oubain
Protein synthesis is in which direction
In eukaryotes the starting amino acid is...
Tropocollagen cross links between_____ to form____

47. Condensed - transciptionally inactive HC- Highly condensed
capped and tail transcript is called
Heterochromatin
Aminoglycosides
mRNA stop codons

48. 3 H bonds
actin and myosin
nonsense
Ehlers Danlos
C- G bond

49. Cleave terminal regions of procollagen to transform into insoluable tropocolagen
Methotrexate
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
Glycosolation
Outside the cell what processing must be done in procolalgen

50. Commonly results in dramatic decrease in amount of gene transcribed
Eukaroytes
Kartageners syndrome
Promoter mutation
Protein synthesis initiation