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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Epithelial cells
cytokeratin
Going APE
Griseofulvin
DNA pol III
2. Cylindrical structure composed of helical array of plymerized dimers of alpha and beta tubulin - flagella - cilia - mitotic spindle - grows slowly collapses quickly
microtubule
mRNA is syntehsized in which direction?
Collagen
kinesin
3. Exocytose procollagen into extracellylar sace
Axonemal dyenin
microtubule
Excocytosis of collagen
dyenin
4. Type III
Euchromatin
RNA polymerases in eukaryotes
What type of collagen is most affected in Ehlers Danlos
Single Strand DNA Repair types
5. H1
The only histone not on the core
Neurofilaments
Elastase is inhibited by
Guanine has a
6. Connective tissue
the tRNA- amino acid bond
Immunohistochemical stains vimentin
DNA pol III
Paclitaxil
7. P53 and RB normally inhibit g1 to S progression
Methotrexate
kinesin
Tumor Suppressors
Excocytosis of collagen
8. Prokaryotic only. Elongates leading strand by adding deoxynucleotides to the 3prime end. Elongates laggin strand. 3 prime to 5 prime exonuclease activity
Cyclin - CDK
DNA pol III
Euchromatin
6MP
9. Inhibits ribonucleotide reductase
tRNA aminoacylation
Heterochromatin
hydroxyurea
C- G bond
10. Splicing out of introns
intermediate filaments
Step Three of RNA processing
White codon is at the 3 prime end of a tRNA
Cell cycle
11. Responsible for the accuracy of amino acid selection
Mebendazole/thiabendazole
Step one of RNA processing
Steps in splicing
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
12. Non homologous end joining
nucleotide
Double Strand DNA repair
mRNA stop codons
Prokaryote RNA pol
13. Less condensed - transciptionally active=eu truly transcobed
tRNA aminoacylation
Molecular motor protiesn
Euchromatin
A- T
14. Site of dteroid synthesis and detoxification of druigs and poisons (liver hepatocytes and steroid horomore adrenal cortex)
nucleotide
Proofreading function in eukaryotic RNA
Smooth ER
Aminoglycosides
15. AD and AR- associated iwth joint dislocation - berry aneurysms - organ rupture
Plasma membrane composition
Labile
Associations of Ehlers Danlos
Which end of the tRNA is the amino acid bound to?
16. Bm - kidney - ears and eyes
Mismatch repair
Type IV collagen is an important structural component of...
Oubain
The only histone not on the core
17. Inhibits thymidylate synthase down thymine
transversion
tRNA
5FU
What type of collagen is most affected in Ehlers Danlos
18. Activated by GTP hydrolosis initiation factors help assembel the 40 S ribosomal subunites with the initiatior tRNA and are released whent he mRNA and the ribosomal subunit assemple with the complex
C- G bond
Order of mitosis
Protein synthesis initiation
Outside the cell what processing must be done in procolalgen
19. Genetic code is conserved throughout evolution
universal
Aminoacylt - tRNA synthetase
Promoter mutation
Proofreading function in eukaryotic RNA
20. Same aa often base change in 3rd position of codon
Alports syndrome
Kartageners syndrome
White codon is at the 3 prime end of a tRNA
silent mutation
21. Checkpoints control transition between phases of cell cycle. regulated by cyclins - CDKs and tumor suppressors. Mitosis (shortest phse)
Which end of a growing DNA strand is the target
Clindamycin
Cell cycle
Introns
22. Inhibits the atpase which increases intracellular sodium which increases intracellular calcium increases cardiaccontractility
What does the hydroxylation of proline and lysine require
Cyclins
Digoxin (cardiac glycosides)
Rough ER
23. Bind 50S blocking translocation
Methotrexate
Prokaryotes
Macrolides
Stable (quiescent)
24. MRNA
Cilia structure
capped and tail transcript is called
helicase
Chloramphenicol
25. 1P blocked by chloramphenicaol and macrolide
Translocation
Molecular motor protiesn
Enhancer
Osteogenesis Imperfecta
26. 1 RNA polymerase (multisubunite complex) makes all 3 kinds of RNA
Axonemal dyenin
DNA pol III
Elastin
Prokaryote RNA pol
27. In the nucleus after transcitpion and only processed RNA is transporte out of the nucleus
chromatin structure
Stable (quiescent)
Introns
RNA processing in eukaryotes occurs
28. 1P (blocked by tetracycline)
Loading tRNA on to ribosome energy requirement
DNA ligase
Single Strand DNA Repair types
Pyrimidines
29. Y shaped region along DNA template where leading and lagging strands are syntehsized
DNA/RNA/Protein syntesis direction
Replication fork
mRNA start codons
mRNA is syntehsized in which direction?
30. The 5prime end (energy for the bond)
transversion
Which end of the nucleotide has the triphosphate
CDKs
Proteosomal degradation
31. Specific glycosylases recognize and remove damaged bases - AP endonuclease cuts DNA at pyrimidne site - empty sugar is removed and the gap is filled and resealed
The only histone not on the core
unambiguous
Base excision repair
Elongation
32. Inhibits dihydrofolate reductase down thymine
Alports syndrome
cytokeratin
Proteosomal degradation
Methotrexate
33. 75-90 nucleotides - 2ary structure cloverleaf form anticodon end is opposite 3 prime aminoacyl end
Cyclin - CDK
5FU
Protein synthesis initiation
tRNA Structure
34. 4 high enrgy bonds
Order of mitosis
Cilia structure
Total energy expenditure requirement for translocation
Which end of a growing DNA strand is the target
35. Lysine/hydroxylysine and combines to form collagen
Tropocollagen cross links between_____ to form____
Elastase is inhibited by
capped and tail transcript is called
Deamination of cytosine makes
36. 9+2 arrangement of microtubules -
Common amino acids in elastin
Axonemal dyenin
Cilia structure
purines
37. Antifungal - act on microtubules
tRNA Structure
helicase
Deamination of cytosine makes
Griseofulvin
38. Aminoacyl - tRNA binds to A site 2) peptidyltransferase catalyzes peptide bond formation transfers growing polypeptie to amino acid in A site 3) ribosome advances 3 nucleotides toward the 3 prime end of RNA moving peptiydyl RNA to P site
trimethoprim
Covalent alterations
Guanine has a
Elongation
39. RNA polymerase I makes rRNA - RNA pol II makes mRNA - RNA pol III makes tRNA
RNA polymerases in eukaryotes
Promoter mutation
RNA processing in eukaryotes occurs
desmin
40. GTP
Mebendazole/thiabendazole
tRNA gripping and going places
Digoxin (cardiac glycosides)
Chloramphenicol
41. 1) primary transcript combines with snRNPs and other proteins to form spliceosome 2) lariat shaped intermediate is generated 3) Lariat is removed and released to precisely join 2 exons
missense mutation
intermediate filaments
GFAP
Steps in splicing
42. The 3 prime hydroxyl of the nascent chain is the target
missense mutation
universal
tRNA aminoacylation
Which end of a growing DNA strand is the target
43. DNA And RNA synthesized in the 5-3 direction
Alports syndrome
Alternate splicing
DNA/RNA/Protein syntesis direction
Fluoroquinolones
44. Prevents stranges from reannealing
histone octamer names
Common amino acids in elastin
single stranded binding proteinds
the tRNA- amino acid bond
45. ATP- AMP (2 phosphoanhydride bonds)
tRNA aminoacylation
Elastin
Common amino acids in elastin
What does the hydroxylation of proline and lysine require
46. A malfunction of mismatch repair (MUt L etc..)
RNA processing in eukaryotes occurs
Xeroderma pigmentosum
Hereditary non polyposis colorectal cancer
Promoter mutation
47. One codon AUG
Order of mitosis
Paclitaxil
Where do introns and exons stay
methionine is only encoded by
48. Intervening noncoding segments of DNA
Post - translational modifications
Introns
Purines
unambiguous
49. Base+ribose+phosphate linked by a phosphodiester bond
Guanine has a
Chediak Higashi syndrome
nucleotide
Single Strand DNA Repair types
50. Greater melting temperature lower fluidity
RNA polymerases in eukaryotes
Higher the cholesterol or long saturated fatty acid content
tRNA Structure
Prokaryotes