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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. 1 RNA polymerase (multisubunite complex) makes all 3 kinds of RNA
nonsense
Axonemal dyenin
Aminoglycosides
Prokaryote RNA pol
2. Never go to Go divide rapidly with short G1 bone marrow - gut epithelium - skin - hair follicles
Cyclins
Hydroxylation of which amino acids are attached to Glycine to form collagen
tRNA
Labile
3. 1) primary transcript combines with snRNPs and other proteins to form spliceosome 2) lariat shaped intermediate is generated 3) Lariat is removed and released to precisely join 2 exons
Nucleotide excision repair
Prokaryote RNA pol
Steps in splicing
Protein synthesis is in which direction
4. Substituting a purine for a pyrimdine or vice versa
transversion
Alports syndrome
What does the hydroxylation of proline and lysine require
Base excision repair
5. Less condensed - transciptionally active=eu truly transcobed
Euchromatin
Common amino acids in elastin
commaless - non - overlapping
GFAP
6. H1
5FU
Cell cycle order
capped and tail transcript is called
The only histone not on the core
7. Activated by GTP hydrolosis initiation factors help assembel the 40 S ribosomal subunites with the initiatior tRNA and are released whent he mRNA and the ribosomal subunit assemple with the complex
polyadenylation does/does not require a template
Functional organization of the gene
Smooth ER
Protein synthesis initiation
8. Close to - far from or even within (in an intron) the gene whose expression it regulates
Gag on pure gold
Enhancers and silencer may be located_____
tRNA gripping and going places
Higher the cholesterol or long saturated fatty acid content
9. P53 and RB normally inhibit g1 to S progression
Kartageners syndrome
Cell cycle
Tumor Suppressors
silent mutation
10. HS1 - HSB - H2 - H4
histone octamer names
capped and tail transcript is called
Glycosolation
Elastin
11. Completed protein is released from ribosme through simple hydrolosis and dissociates
Molecular motor protiesn
Steps in splicing
Ehlers Danlos
Termination
12. Intervening noncoding segments of DNA
purines
Xeroderma pigmentosum
RNA processing in eukaryotes occurs
Introns
13. Commonly results in dramatic decrease in amount of gene transcribed
purines
Promoter mutation
trimethoprim
Chloramphenicol
14. Change resulting in early stop codon
Glycosolation
nonsense
Post - translational modifications
Free ribosomes
15. In the nucleus after transcitpion and only processed RNA is transporte out of the nucleus
Tumor Suppressors
Plasma membrane composition
dyenin
RNA processing in eukaryotes occurs
16. Hn RNA
Pyrimidines
Methotrexate
Initial transcript without processing is known as
Silencer
17. Bm - kidney - ears and eyes
Collagen
Type IV collagen is an important structural component of...
transversion
Stable (quiescent)
18. Each codon specifies only 1 amino acid
Elastase is inhibited by
chromatin structure
origin of replication
unambiguous
19. The 5prime end (energy for the bond)
origin of replication
Which end of the nucleotide has the triphosphate
Elongation
Oubain
20. Enter G1 from G0 when stimulated Hepatocytes/lymphocytes
Protein synthesis is in which direction
Double Strand DNA repair
Stable (quiescent)
Outside the cell what processing must be done in procolalgen
21. Alpha 1 antitrypisn
tRNA activation
Elastase is inhibited by
Which end of the nucleotide has the triphosphate
promoter
22. Retrograde to microtubules
dyenin
methionine is only encoded by
What type of collagen is most affected in Ehlers Danlos
Step Three of RNA processing
23. Must be both activated and inactivated for cell cycle to progress
Total energy expenditure requirement for translocation
Cyclin - CDK
Replication fork
Rough ER
24. Inhibits thymidylate synthase down thymine
Order of mitosis
5FU
Guanine has a
Hereditary non polyposis colorectal cancer
25. 75-90 nucleotides - 2ary structure cloverleaf form anticodon end is opposite 3 prime aminoacyl end
desmin
Ehlers Danlos
tRNA Structure
Nucleotide excision repair
26. Inhibits by binding to the potassium side
CDKs
Oubain
Translocation
A- T
27. (A - G) 2 rings Pure As Gold
actin and myosin
Double Strand DNA repair
mRNA stop codons
Purines
28. Inhibits the atpase which increases intracellular sodium which increases intracellular calcium increases cardiaccontractility
dyenin
Digoxin (cardiac glycosides)
DNA/RNA/Protein syntesis direction
Gag on pure gold
29. Inhibits ribonucleotide reductase
Purines
Aminoacylt - tRNA synthetase
hydroxyurea
Total energy expenditure requirement for translocation
30. Bind 50S blocking translocation
Macrolides
alpha amintin
Stable (quiescent)
Base excision repair
31. The 3 prime hydroxyl of the nascent chain is the target
nonsense
Proofreading function in eukaryotic RNA
Which end of a growing DNA strand is the target
GFAP
32. Ribonucleotide reductase
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
tRNA Structure
Sodium K ATPase
Enhancer
33. Cleave terminal regions of procollagen to transform into insoluable tropocolagen
Outside the cell what processing must be done in procolalgen
Euchromatin
Common amino acids in elastin
Protein synthesis is in which direction
34. Neurons
Mebendazole/thiabendazole
universal
AUG codes For what in prokaryotes
Neurofilaments
35. Trimming removal of n or c terminal propeptides from zymogens to generate mature proteinds
Post - translational modifications
Cell cycle order
origin of replication
Digoxin (cardiac glycosides)
36. Checkpoints control transition between phases of cell cycle. regulated by cyclins - CDKs and tumor suppressors. Mitosis (shortest phse)
capped and tail transcript is called
Cyclin - CDK
Eukaroytes
Cell cycle
37. Microvilli - muscle contraction - cytokinesis - adhering juntions
actin and myosin
Purines
Single Strand DNA Repair types
Hydroxylation of which amino acids are attached to Glycine to form collagen
38. Attachment of ubiquitin to defective proteinds to tag them for breakdown
Pyrimidines
Proteosomal degradation
What type of collagen is most affected in Ehlers Danlos
Alports syndrome
39. One codon AUG
Introns
Chediak Higashi syndrome
methionine is only encoded by
GFAP
40. Remain in G0 regenerate from stem cells
tRNA aminoacylation
Permanent cells
helicase
Methotrexate
41. Muscle
microtubule
desmin
frame shift
transition
42. Introns stay In the nucleus whereas EXons EXit and are EXpressed
Xeroderma pigmentosum
What ties teh nucleosome together
promoter
Where do introns and exons stay
43. 3 H bonds
C- G bond
6MP
Post - translational modifications
Base excision repair
44. Antifungal - act on microtubules
Griseofulvin
Axonemal dyenin
chromatin structure
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
45. Elastase
Mebendazole/thiabendazole
Prokaryote RNA pol
6MP
Elastin is broken down by
46. Made from orogate precuror with PRPP added later
pyrimadines
missense mutation
Common amino acids in elastin
Non homologous end joining
47. You glyucosolate hte pro - alpha chain lysine resudens and form procollagen (triple helix of alpha chains)
Thymine has a
universal
nonsense
Glycosolation
48. RER translation of collagen alpha chains (preprocollagen) usually Gly-X-Y
Collagedn synthesis where?
dyenin
DNA pol III
Deamination of cytosine makes
49. Cilia - glagella - mitotic spindle - neurons - centrioles
tRNA Structure
Tropocollagen cross links between_____ to form____
microtubule
Cell cycle order
50. Brings together 2 ends of DNA fragments no requirement for homology
frame shift
Non homologous end joining
Covalent alterations
Immunohistochemical stains vimentin