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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Unmethylated - newly synthesized string is recognized - mismatched nucleotides are removed and the gap is filled and resealed
Mismatch repair
Neurofilaments
Going APE
tRNA activation
2. Enter G1 from G0 when stimulated Hepatocytes/lymphocytes
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
Osteogenesis Imperfecta
Stable (quiescent)
Cell cycle
3. ATP- AMP (2 phosphoanhydride bonds)
desmin
Fluoroquinolones
tRNA aminoacylation
transversion
4. Commonly results in dramatic decrease in amount of gene transcribed
Macrolides
chromatin structure
desmin
Promoter mutation
5. Antifungal - act on microtubules
Excocytosis of collagen
Griseofulvin
RNA polymerases in eukaryotes
intermediate filaments
6. Contain the actual genetic information coding for protein
Going APE
Exons
Guanine has a
DNA pol III
7. Greater melting temperature lower fluidity
alpha amintin
universal
Order of mitosis
Higher the cholesterol or long saturated fatty acid content
8. Does not
Enhancers and silencer may be located_____
polyadenylation does/does not require a template
Labile
C- G bond
9. DNA And RNA synthesized in the 5-3 direction
Which end of the tRNA is the amino acid bound to?
Chediak Higashi syndrome
DNA/RNA/Protein syntesis direction
origin of replication
10. Activated by GTP hydrolosis initiation factors help assembel the 40 S ribosomal subunites with the initiatior tRNA and are released whent he mRNA and the ribosomal subunit assemple with the complex
What type of collagen is most affected in Ehlers Danlos
Cholchicine
Thymine has a
Protein synthesis initiation
11. Inhibits dihydrofolate reductase down thymine
GFAP
tRNA activation
Methotrexate
Xeroderma pigmentosum
12. Cyclin depndent kinases; consituative and inactive
RNA processing in eukaryotes occurs
White codon is at the 3 prime end of a tRNA
CDKs
Gag on pure gold
13. CUT 1 ring Cut the Py
C- G bond
Which end of the nucleotide has the triphosphate
nonsense
Pyrimidines
14. Ketone
Single Strand DNA Repair types
tRNA activation
Guanine has a
trimethoprim
15. H1
commaless - non - overlapping
Collagen
Smooth ER
The only histone not on the core
16. Unwinds DNA template at replication fork
tRNA Structure
microtubule
helicase
kinesin
17. Microvilli - muscle contraction - cytokinesis - adhering juntions
alpha amintin
actin and myosin
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
nucleosid
18. Each codon specifies only 1 amino acid
intermediate filaments
Fluoroquinolones
unambiguous
Plasma membrane composition
19. Type III
Cell cycle
What type of collagen is most affected in Ehlers Danlos
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
DNA pol III
20. Change resulting in misreading of all nucleotides downstream - usually resulting in a truncated non functional protien
Single Strand DNA Repair types
Where do introns and exons stay
Order of mitosis
frame shift
21. (A - G) 2 rings Pure As Gold
Translocation
DNA ligase
Eukaroytes
Purines
22. Has enough energy to created the peptide bond
the tRNA- amino acid bond
nucleotide
What does the hydroxylation of proline and lysine require
microtubule
23. Attachment of ubiquitin to defective proteinds to tag them for breakdown
Steps in splicing
microtubule
Proteosomal degradation
Labile
24. Strethchy protein within lungs - large artiers - elastic liaments - vocal cords - ligamenta flava)
the tRNA- amino acid bond
In eukaryotes the starting amino acid is...
Elastin
origin of replication
25. Checkpoints control transition between phases of cell cycle. regulated by cyclins - CDKs and tumor suppressors. Mitosis (shortest phse)
Cell cycle
Non homologous end joining
Elastin
Osteogenesis Imperfecta
26. Must be both activated and inactivated for cell cycle to progress
desmin
nucleotide
Smooth ER
Cyclin - CDK
27. Proline - glycine
Oubain
microtubule
Common amino acids in elastin
A- T
28. You glyucosolate hte pro - alpha chain lysine resudens and form procollagen (triple helix of alpha chains)
Smooth ER
Excocytosis of collagen
Glycosolation
Methotrexate
29. Bm - kidney - ears and eyes
dyenin
Primase
DNA ligase
Type IV collagen is an important structural component of...
30. No proofreading function but can initiate chains. RNA poymerase II opens DNA at promoter site
Outside the cell what processing must be done in procolalgen
Proofreading function in eukaryotic RNA
kinesin
promoter
31. Less condensed - transciptionally active=eu truly transcobed
tRNA gripping and going places
Total energy expenditure requirement for translocation
Oubain
Euchromatin
32. ATP ase that links peripheral 9 doublets and causes bending of cilium by differential sliding of doublets
Tumor Suppressors
Axonemal dyenin
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
Heterochromatin
33. Methyl THYmine has a meTHYl
Cyclins
Thymine has a
Collagen
Common amino acids in elastin
34. Nucleotide excision repair - Base Excision repair - Mismath repair
Immunohistochemical stains vimentin
Steps in splicing
Single Strand DNA Repair types
Going APE
35. A site - incoming aminoacyl tRNA - Psite accomodates growing Peptide - E site holds EmplytRNA as it exits
Kartageners syndrome
Alternate splicing
Going APE
Where do introns and exons stay
36. H1 string
DNA topoisomerases
What ties teh nucleosome together
Aminoglycosides
actin and myosin
37. AUG inAUGurates protein synthesis
chromatin structure
Elastin is broken down by
mRNA start codons
cytokeratin
38. Base + ribose
nucleosid
Nucleotide excision repair
tRNA activation
Osteogenesis Imperfecta
39. Prokaryotic only. Elongates leading strand by adding deoxynucleotides to the 3prime end. Elongates laggin strand. 3 prime to 5 prime exonuclease activity
DNA pol III
Step one of RNA processing
transition
nucleotide
40. Different exons can be combined to make nique protiens in different times
What does the hydroxylation of proline and lysine require
Elastin is broken down by
Alternate splicing
Double Strand DNA repair
41. Specific endonucleases release the oligonucleotide containing damaged bases. DNA polymerase and logase fill and resealt eh gap
Post - translational modifications
mRNA stop codons
A- T
Nucleotide excision repair
42. Seals
single stranded binding proteinds
DNA ligase
Tetracyclines
Osteogenesis Imperfecta
43. UGA - UAG - UAA
Order of mitosis
Cell cycle order
mRNA stop codons
promoter
44. Completed protein is released from ribosme through simple hydrolosis and dissociates
Termination
Stable (quiescent)
nucleotide
Non homologous end joining
45. More than 1 codon may code for the same amino acid
degenerate or redundant
CDKs
tRNA activation
Cholchicine
46. Asymmetric fluid bilayer - contains - cholesterol - phospholipids - sphingoplipids - glycolipids - and protiends
Plasma membrane composition
chromatin structure
nonsense
cytokeratin
47. A malfunction of mismatch repair (MUt L etc..)
polyadenylation does/does not require a template
tRNA gripping and going places
Hereditary non polyposis colorectal cancer
actin and myosin
48. RER translation of collagen alpha chains (preprocollagen) usually Gly-X-Y
Silencer
5FU
DNA/RNA/Protein syntesis direction
Collagedn synthesis where?
49. P53 and RB normally inhibit g1 to S progression
purines
Purines
Tumor Suppressors
Oubain
50. Exocytose procollagen into extracellylar sace
Where do introns and exons stay
Tumor Suppressors
Excocytosis of collagen
Chloramphenicol