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First Aid: Biochemistry Molecular

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Substituting a pyramidine for a pyrimadine






2. Uracil






3. Negatively charged DNA loops twice around histone octamers create a nucloesome bead.






4. AD and AR- associated iwth joint dislocation - berry aneurysms - organ rupture






5. Made from orogate precuror with PRPP added later






6. Prokaryotic only. Elongates leading strand by adding deoxynucleotides to the 3prime end. Elongates laggin strand. 3 prime to 5 prime exonuclease activity






7. Inhbits RNA pol II (found in death cap mushrooms)






8. Hn RNA






9. Each codon specifies only 1 amino acid






10. Inhibits by binding to the potassium side






11. Nucleotide excision repair - Base Excision repair - Mismath repair






12. Blocks denovo purine synthesis






13. Bm - kidney - ears and eyes






14. Has enough energy to created the peptide bond






15. Condensed - transciptionally inactive HC- Highly condensed






16. Inhibits thymidylate synthase down thymine






17. Bind 50S blocking translocation






18. Connective tissue






19. In the nucleus after transcitpion and only processed RNA is transporte out of the nucleus






20. AUG inAUGurates protein synthesis






21. Inhibits ribonucleotide reductase






22. Xlinked recessive IV collagen bm - kidney - ear and eye -- nephritis and defness ocular disturbances






23. Made from IMP precursor






24. Site of secretory protiens (mucus secreting goblet cells and antibody secreting cells)






25. 1) primary transcript combines with snRNPs and other proteins to form spliceosome 2) lariat shaped intermediate is generated 3) Lariat is removed and released to precisely join 2 exons






26. Unwinds DNA template at replication fork






27. Mutation in nucleotide excision repair Dry skin with melanoma and other cancers






28. Binds 50S blocking translocation






29. Exocytose procollagen into extracellylar sace






30. Must be both activated and inactivated for cell cycle to progress






31. Capping on 5 prime end (7 methylguanosine) -






32. Neuroglia






33. Change resulting in misreading of all nucleotides downstream - usually resulting in a truncated non functional protien






34. Anterograde to microtubule






35. Cleave terminal regions of procollagen to transform into insoluable tropocolagen






36. Antigout - acts on mts






37. VItamin C






38. Non homologous end joining






39. Contain the actual genetic information coding for protein






40. Substituting a purine for a pyrimdine or vice versa






41. Genetic bone disorder (brittle bone disease) type 1 colalgen - fractures (during birth) 2) Blue sclerae 3) hearing loss 4) dental imperfections 1:10000 may be confused with child abuse






42. Phosphorylation - glycosloation - hyderoxylation






43. Tansport cellular cargo toward opposite ends of microtubule tracks






44. Codes for formyl methionine (f - Met)






45. (A - G) 2 rings Pure As Gold






46. Inhibits dihydrofolate reductase down thymine






47. 2 H bonds greater GC content greater melting point






48. Microtubule polymerization defect resulting in lowered phagocytosis. results in recurrent pyogenic infections - partial albinism and peripheral neuropathy






49. 1P (blocked by tetracycline)






50. Brings together 2 ends of DNA fragments no requirement for homology