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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. The 3 prime hydroxyl of the nascent chain is the target
Which end of a growing DNA strand is the target
Clindamycin
Xeroderma pigmentosum
origin of replication
2. Responsible for the accuracy of amino acid selection
capped and tail transcript is called
Step one of RNA processing
Tropocollagen cross links between_____ to form____
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
3. 1P blocked by chloramphenicaol and macrolide
Collagen
Which end of the nucleotide has the triphosphate
Chediak Higashi syndrome
Translocation
4. Commonly results in dramatic decrease in amount of gene transcribed
intermediate filaments
Elastin is broken down by
Steps in splicing
Promoter mutation
5. Faulty collagen synthesis causing 1) hyperextensible skin 2) tendency to bleed 3) hypermobile joints
nucleosid
Ehlers Danlos
Which is the most and least abundant type of RNA
Initial transcript without processing is known as
6. Hydroxy proline and hydroxylysine
degenerate or redundant
Hydroxylation of which amino acids are attached to Glycine to form collagen
Base excision repair
mRNA stop codons
7. Site of secretory protiens (mucus secreting goblet cells and antibody secreting cells)
What ties teh nucleosome together
Molecular motor protiesn
Rough ER
Proofreading function in eukaryotic RNA
8. Activated by GTP hydrolosis initiation factors help assembel the 40 S ribosomal subunites with the initiatior tRNA and are released whent he mRNA and the ribosomal subunit assemple with the complex
Protein synthesis initiation
desmin
Collagedn synthesis where?
Going APE
9. Promoter - enhancer - promoter - TATA- transcription initiation site - coding region (including exons and introns) and then the AATAAA
Prokaryotes
Functional organization of the gene
Protein synthesis is in which direction
nucleotide
10. Anit helminth - act on microtubules
tRNA
Mebendazole/thiabendazole
Loading tRNA on to ribosome energy requirement
origin of replication
11. Ketone
Guanine has a
Prokaryote RNA pol
mRNA start codons
Molecular motor protiesn
12. MRNA
capped and tail transcript is called
Excocytosis of collagen
Which is the most and least abundant type of RNA
Paclitaxil
13. Inhibits dihydrofolate reductase down thymine
Axonemal dyenin
Methotrexate
silent mutation
tRNA Structure
14. Neurons
DNA pol III
Prokaryotes
Neurofilaments
Purines
15. Asymmetric fluid bilayer - contains - cholesterol - phospholipids - sphingoplipids - glycolipids - and protiends
transition
Plasma membrane composition
tRNA Structure
Proofreading function in eukaryotic RNA
16. 2 H bonds greater GC content greater melting point
transition
Fluoroquinolones
A- T
Xeroderma pigmentosum
17. (A - G) 2 rings Pure As Gold
Purines
Termination
tRNA aminoacylation
Macrolides
18. 1 RNA polymerase (multisubunite complex) makes all 3 kinds of RNA
Order of mitosis
Covalent alterations
single stranded binding proteinds
Prokaryote RNA pol
19. Anterograde to microtubule
methionine is only encoded by
commaless - non - overlapping
kinesin
trimethoprim
20. Base+ribose+phosphate linked by a phosphodiester bond
nucleotide
GFAP
Total energy expenditure requirement for translocation
Fluoroquinolones
21. Microtubule polymerization defect resulting in lowered phagocytosis. results in recurrent pyogenic infections - partial albinism and peripheral neuropathy
Chediak Higashi syndrome
Griseofulvin
cytokeratin
intermediate filaments
22. Scrutinizes aa before and after it binds to tRNA. If incorrect bond is hydrolyzed.
Protein synthesis is in which direction
Aminoacylt - tRNA synthetase
Post - translational modifications
Mebendazole/thiabendazole
23. AD and AR- associated iwth joint dislocation - berry aneurysms - organ rupture
microtubule
Associations of Ehlers Danlos
Elastin is broken down by
Xeroderma pigmentosum
24. Inhibits thymidylate synthase down thymine
5FU
Steps in splicing
AUG codes For what in prokaryotes
Initial transcript without processing is known as
25. Remain in G0 regenerate from stem cells
Permanent cells
Tumor Suppressors
Immunohistochemical stains vimentin
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
26. Site where negative regulators bind
hydroxyurea
GFAP
mRNA start codons
Silencer
27. Substituting a purine for a pyrimdine or vice versa
tRNA gripping and going places
Griseofulvin
transversion
Hydroxylation of which amino acids are attached to Glycine to form collagen
28. Inhibits the atpase which increases intracellular sodium which increases intracellular calcium increases cardiaccontractility
dyenin
Cell cycle
Digoxin (cardiac glycosides)
histone octamer names
29. Microvilli - muscle contraction - cytokinesis - adhering juntions
mRNA stop codons
actin and myosin
Prokaryote RNA pol
Heterochromatin
30. Neuroglia
C- G bond
Gag on pure gold
tRNA aminoacylation
GFAP
31. Made from IMP precursor
6MP
White codon is at the 3 prime end of a tRNA
nonsense
purines
32. Odd 30S plus 50 S=70S
helicase
Aminoglycosides
silent mutation
Prokaryotes
33. Hn RNA
Elongation
White codon is at the 3 prime end of a tRNA
Initial transcript without processing is known as
desmin
34. VItamin C
the tRNA- amino acid bond
step two of RNA processing
What does the hydroxylation of proline and lysine require
kinesin
35. Cleave terminal regions of procollagen to transform into insoluable tropocolagen
Outside the cell what processing must be done in procolalgen
Exons
Guanine has a
dyenin
36. Condensed - transciptionally inactive HC- Highly condensed
Heterochromatin
promoter
Rough ER
Fluoroquinolones
37. Never go to Go divide rapidly with short G1 bone marrow - gut epithelium - skin - hair follicles
desmin
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
actin and myosin
Labile
38. Bind 50S blocking translocation
Macrolides
Prokaryote RNA pol
Smooth ER
Hydroxylation of which amino acids are attached to Glycine to form collagen
39. Site of dteroid synthesis and detoxification of druigs and poisons (liver hepatocytes and steroid horomore adrenal cortex)
Covalent alterations
6MP
Steps in splicing
Smooth ER
40. Codes for formyl methionine (f - Met)
AUG codes For what in prokaryotes
DNA ligase
Heterochromatin
the tRNA- amino acid bond
41. Blocks denovo purine synthesis
6MP
mRNA start codons
desmin
Aminoacylt - tRNA synthetase
42. Uracil
Digoxin (cardiac glycosides)
Introns
Deamination of cytosine makes
Which end of the tRNA is the amino acid bound to?
43. In the nucleus after transcitpion and only processed RNA is transporte out of the nucleus
degenerate or redundant
GFAP
Methotrexate
RNA processing in eukaryotes occurs
44. RNA polymerase I makes rRNA - RNA pol II makes mRNA - RNA pol III makes tRNA
RNA polymerases in eukaryotes
Griseofulvin
Cholchicine
Axonemal dyenin
45. Methionine - which may be removed before translation is completed
In eukaryotes the starting amino acid is...
tRNA
Cholchicine
Primase
46. 9+2 arrangement of microtubules -
intermediate filaments
Cilia structure
desmin
Cholchicine
47. Brings together 2 ends of DNA fragments no requirement for homology
Neurofilaments
frame shift
Vincristine/Vinblastine
Non homologous end joining
48. Site where RNA polymerase and multiple other transciption factors bind to DNA upstream from gene locus (AT rich upstream sequence with TATA and CAAT boxes)
Osteogenesis Imperfecta
promoter
Which end of the tRNA is the amino acid bound to?
Mismatch repair
49. A site - incoming aminoacyl tRNA - Psite accomodates growing Peptide - E site holds EmplytRNA as it exits
Going APE
Post - translational modifications
mRNA start codons
Vincristine/Vinblastine
50. The 5prime end (energy for the bond)
Post - translational modifications
Which end of the nucleotide has the triphosphate
Aminoglycosides
White codon is at the 3 prime end of a tRNA