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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Create a nick in the helix to relieve supercoils created during replication
Cell cycle
Common amino acids in elastin
Labile
DNA topoisomerases
2. Must be both activated and inactivated for cell cycle to progress
intermediate filaments
Cyclin - CDK
Introns
Which end of a growing DNA strand is the target
3. Binds 50S blocking translocation
Clindamycin
Methotrexate
Rough ER
What type of collagen is most affected in Ehlers Danlos
4. 1P (blocked by tetracycline)
Loading tRNA on to ribosome energy requirement
RNA polymerases in eukaryotes
step two of RNA processing
Alports syndrome
5. Aminoacyl - tRNA binds to A site 2) peptidyltransferase catalyzes peptide bond formation transfers growing polypeptie to amino acid in A site 3) ribosome advances 3 nucleotides toward the 3 prime end of RNA moving peptiydyl RNA to P site
Which end of the tRNA is the amino acid bound to?
Step Three of RNA processing
Elongation
Exons
6. Y shaped region along DNA template where leading and lagging strands are syntehsized
Replication fork
tRNA Structure
Which is the most and least abundant type of RNA
origin of replication
7. UGA - UAG - UAA
Neurofilaments
mRNA stop codons
Termination
Proteosomal degradation
8. Different exons can be combined to make nique protiens in different times
Alternate splicing
Replication fork
Ehlers Danlos
purines
9. Anit helminth - act on microtubules
Mebendazole/thiabendazole
Permanent cells
Chediak Higashi syndrome
hydroxyurea
10. CCA AT 3 PRIME END
White codon is at the 3 prime end of a tRNA
Thymine has a
DNA topoisomerases
Double Strand DNA repair
11. Stretch of DNA that alters gene expression by binding transcription factors
Digoxin (cardiac glycosides)
tRNA gripping and going places
unambiguous
Enhancer
12. Responsible for the accuracy of amino acid selection
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
Collagedn synthesis where?
What type of collagen is most affected in Ehlers Danlos
13. Intervening noncoding segments of DNA
Proteosomal degradation
Single Strand DNA Repair types
DNA pol I
Introns
14. Never go to Go divide rapidly with short G1 bone marrow - gut epithelium - skin - hair follicles
Labile
Cholchicine
helicase
tRNA
15. Proline - glycine
Common amino acids in elastin
DNA topoisomerases
Elastase is inhibited by
helicase
16. Elastase
Elastin is broken down by
step two of RNA processing
Steps in splicing
nonsense
17. Base + ribose
nucleosid
single stranded binding proteinds
Higher the cholesterol or long saturated fatty acid content
Thymine has a
18. Inhibit DNA gyrase (specific prokaryotic topoisomerase)
Fluoroquinolones
single stranded binding proteinds
RNA polymerases in eukaryotes
DNA/RNA/Protein syntesis direction
19. Epithelial cells
Which end of the nucleotide has the triphosphate
Elastin
cytokeratin
Prokaryote RNA pol
20. Introns stay In the nucleus whereas EXons EXit and are EXpressed
Introns
Example of permanent cells
Where do introns and exons stay
silent mutation
21. Particular sequnece in genomre where DNA replication begins. May be single (prokaryotes) or multiple (eukaryotes)
Exons
Elastin is broken down by
The only histone not on the core
origin of replication
22. Type III
desmin
cytokeratin
What ties teh nucleosome together
What type of collagen is most affected in Ehlers Danlos
23. 1 RNA polymerase (multisubunite complex) makes all 3 kinds of RNA
DNA/RNA/Protein syntesis direction
Prokaryote RNA pol
Tumor Suppressors
dyenin
24. Close to - far from or even within (in an intron) the gene whose expression it regulates
Enhancers and silencer may be located_____
Single Strand DNA Repair types
Clindamycin
chromatin structure
25. Exocytose procollagen into extracellylar sace
Total energy expenditure requirement for translocation
mRNA stop codons
Proteosomal degradation
Excocytosis of collagen
26. Even 40S 60S =80S
Outside the cell what processing must be done in procolalgen
Eukaroytes
Alports syndrome
the tRNA- amino acid bond
27. Changed aaconservative - new aa is similar in chemical structure
Collagen
mRNA stop codons
missense mutation
the tRNA- amino acid bond
28. Regulatory proteins that control cell cycle events; phase specific; activated CDKs
Cyclins
DNA pol III
Immunohistochemical stains vimentin
Free ribosomes
29. HS1 - HSB - H2 - H4
histone octamer names
Fluoroquinolones
Macrolides
transition
30. Unmethylated - newly synthesized string is recognized - mismatched nucleotides are removed and the gap is filled and resealed
Mismatch repair
Elongation
nucleosid
purines
31. 1) primary transcript combines with snRNPs and other proteins to form spliceosome 2) lariat shaped intermediate is generated 3) Lariat is removed and released to precisely join 2 exons
silent mutation
Which end of a growing DNA strand is the target
Steps in splicing
tRNA
32. ATP- AMP (2 phosphoanhydride bonds)
Single Strand DNA Repair types
the tRNA- amino acid bond
Double Strand DNA repair
tRNA aminoacylation
33. A malfunction of mismatch repair (MUt L etc..)
Excocytosis of collagen
Going APE
Hereditary non polyposis colorectal cancer
Aminoacylt - tRNA synthetase
34. Change resulting in early stop codon
Gag on pure gold
Fluoroquinolones
nonsense
Exons
35. Odd 30S plus 50 S=70S
Chloramphenicol
Example of permanent cells
actin and myosin
Prokaryotes
36. Bind 30S subunit preventing attachment of aminoacyl - tRNA
Tetracyclines
Osteogenesis Imperfecta
Elastin
Cyclin - CDK
37. Ribonucleotide reductase
actin and myosin
Initial transcript without processing is known as
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
universal
38. Negatively charged DNA loops twice around histone octamers create a nucloesome bead.
chromatin structure
Tropocollagen cross links between_____ to form____
C- G bond
alpha amintin
39. GTP
Vincristine/Vinblastine
Functional organization of the gene
tRNA gripping and going places
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
40. Completed protein is released from ribosme through simple hydrolosis and dissociates
Labile
Cell cycle
Termination
tRNA activation
41. Nucleotide excision repair - Base Excision repair - Mismath repair
Single Strand DNA Repair types
Guanine has a
Free ribosomes
helicase
42. Cylindrical structure composed of helical array of plymerized dimers of alpha and beta tubulin - flagella - cilia - mitotic spindle - grows slowly collapses quickly
Macrolides
Cell cycle order
microtubule
Example of permanent cells
43. Alpha 1 antitrypisn
Elastase is inhibited by
tRNA
mRNA is syntehsized in which direction?
Which is the most and least abundant type of RNA
44. Same aa often base change in 3rd position of codon
Thymine has a
Collagedn synthesis where?
Vincristine/Vinblastine
silent mutation
45. Unattached to any membrane; site of cytosolic and organeller prtoeins
Termination
Pyrimidines
Free ribosomes
Glycosolation
46. H1 string
Euchromatin
Cholchicine
Elastase is inhibited by
What ties teh nucleosome together
47. Greater melting temperature lower fluidity
Paclitaxil
Cell cycle order
Protein synthesis is in which direction
Higher the cholesterol or long saturated fatty acid content
48. Inhibits the atpase which increases intracellular sodium which increases intracellular calcium increases cardiaccontractility
kinesin
Digoxin (cardiac glycosides)
Proofreading function in eukaryotic RNA
Aminoacylt - tRNA synthetase
49. Commonly results in dramatic decrease in amount of gene transcribed
Stable (quiescent)
Promoter mutation
histone octamer names
missense mutation
50. Remain in G0 regenerate from stem cells
Ehlers Danlos
nucleotide
Permanent cells
Single Strand DNA Repair types