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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Microtubule polymerization defect resulting in lowered phagocytosis. results in recurrent pyogenic infections - partial albinism and peripheral neuropathy
Example of permanent cells
Chediak Higashi syndrome
actin and myosin
Elastase is inhibited by
2. Site where RNA polymerase and multiple other transciption factors bind to DNA upstream from gene locus (AT rich upstream sequence with TATA and CAAT boxes)
Which end of the nucleotide has the triphosphate
nucleotide
actin and myosin
promoter
3. (A - G) 2 rings Pure As Gold
Base excision repair
Total energy expenditure requirement for translocation
Purines
Tumor Suppressors
4. Negatively charged DNA loops twice around histone octamers create a nucloesome bead.
Gag on pure gold
silent mutation
chromatin structure
The only histone not on the core
5. Anti cancer - act on microtubules
Vincristine/Vinblastine
CDKs
Tetracyclines
Proteosomal degradation
6. Ketone
Non homologous end joining
Elastin is broken down by
Guanine has a
alpha amintin
7. Retrograde to microtubules
frame shift
dyenin
Xeroderma pigmentosum
The only histone not on the core
8. 5 prime to 3 prime
What ties teh nucleosome together
mRNA is syntehsized in which direction?
dyenin
Ehlers Danlos
9. Condensed - transciptionally inactive HC- Highly condensed
chromatin structure
Oubain
Heterochromatin
Tumor Suppressors
10. Binds 50S blocking translocation
5FU
tRNA gripping and going places
Clindamycin
methionine is only encoded by
11. Base+ribose+phosphate linked by a phosphodiester bond
nucleotide
microtubule
Order of mitosis
capped and tail transcript is called
12. More than 1 codon may code for the same amino acid
universal
Protein synthesis initiation
degenerate or redundant
GFAP
13. In the nucleus after transcitpion and only processed RNA is transporte out of the nucleus
Sodium K ATPase
missense mutation
RNA processing in eukaryotes occurs
Base excision repair
14. Specific glycosylases recognize and remove damaged bases - AP endonuclease cuts DNA at pyrimidne site - empty sugar is removed and the gap is filled and resealed
RNA polymerases in eukaryotes
Base excision repair
Total energy expenditure requirement for translocation
trimethoprim
15. Brings together 2 ends of DNA fragments no requirement for homology
What type of collagen is most affected in Ehlers Danlos
Non homologous end joining
hydroxyurea
desmin
16. Muscle
Termination
desmin
Ehlers Danlos
Enhancers and silencer may be located_____
17. Change resulting in early stop codon
nonsense
kinesin
histone octamer names
Alternate splicing
18. The N to C
Going APE
degenerate or redundant
unambiguous
Protein synthesis is in which direction
19. Commonly results in dramatic decrease in amount of gene transcribed
Promoter mutation
Going APE
Pyrimidines
tRNA Structure
20. Cleave terminal regions of procollagen to transform into insoluable tropocolagen
Outside the cell what processing must be done in procolalgen
Where do introns and exons stay
chromatin structure
nucleosid
21. Inhibits 50S peptidyl transferase
Elastin is broken down by
Aminoglycosides
Thymine has a
Chloramphenicol
22. Elastase
Where do introns and exons stay
Hereditary non polyposis colorectal cancer
Alternate splicing
Elastin is broken down by
23. Ribonucleotide reductase
Collagedn synthesis where?
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
Osteogenesis Imperfecta
Labile
24. Different exons can be combined to make nique protiens in different times
Alternate splicing
Double Strand DNA repair
purines
Common amino acids in elastin
25. Inhibit DNA gyrase (specific prokaryotic topoisomerase)
Exons
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
Fluoroquinolones
Steps in splicing
26. 1 RNA polymerase (multisubunite complex) makes all 3 kinds of RNA
Mebendazole/thiabendazole
Prokaryote RNA pol
Eukaroytes
What does the hydroxylation of proline and lysine require
27. Prokaryotic only. Degrades RNA primer and fills in the gap with DNA (5 prime to 3 prime exonuclease)
Excocytosis of collagen
DNA pol I
Cyclins
Smooth ER
28. Splicing out of introns
Primase
microtubule
Step Three of RNA processing
Elastase is inhibited by
29. Faulty collagen synthesis causing 1) hyperextensible skin 2) tendency to bleed 3) hypermobile joints
nucleosid
Higher the cholesterol or long saturated fatty acid content
Ehlers Danlos
Smooth ER
30. Genetic code is conserved throughout evolution
Cilia structure
tRNA activation
Which is the most and least abundant type of RNA
universal
31. Completed protein is released from ribosme through simple hydrolosis and dissociates
degenerate or redundant
5FU
DNA/RNA/Protein syntesis direction
Termination
32. Codes for formyl methionine (f - Met)
Alternate splicing
Clindamycin
AUG codes For what in prokaryotes
Plasma membrane composition
33. Bind 30S subunit preventing attachment of aminoacyl - tRNA
Tetracyclines
Which is the most and least abundant type of RNA
Outside the cell what processing must be done in procolalgen
Stable (quiescent)
34. Non homologous end joining
Exons
Base excision repair
Double Strand DNA repair
Chloramphenicol
35. ATP- AMP (2 phosphoanhydride bonds)
Aminoglycosides
Prokaryotes
tRNA aminoacylation
Macrolides
36. Anterograde to microtubule
degenerate or redundant
Gag on pure gold
Cell cycle
kinesin
37. 4 high enrgy bonds
Total energy expenditure requirement for translocation
What type of collagen is most affected in Ehlers Danlos
Primase
Going APE
38. Y shaped region along DNA template where leading and lagging strands are syntehsized
Replication fork
GFAP
capped and tail transcript is called
Example of permanent cells
39. 1P blocked by chloramphenicaol and macrolide
What type of collagen is most affected in Ehlers Danlos
Translocation
Hydroxylation of which amino acids are attached to Glycine to form collagen
RNA processing in eukaryotes occurs
40. Alpha 1 antitrypisn
Replication fork
Enhancers and silencer may be located_____
promoter
Elastase is inhibited by
41. Three amino acids necessary for purine synthesis= glutamine - aspartate and glycine
Hereditary non polyposis colorectal cancer
Eukaroytes
Kartageners syndrome
Gag on pure gold
42. Unattached to any membrane; site of cytosolic and organeller prtoeins
Total energy expenditure requirement for translocation
Excocytosis of collagen
Free ribosomes
White codon is at the 3 prime end of a tRNA
43. Prevents stranges from reannealing
Cell cycle order
single stranded binding proteinds
desmin
actin and myosin
44. Prokaryotic only. Elongates leading strand by adding deoxynucleotides to the 3prime end. Elongates laggin strand. 3 prime to 5 prime exonuclease activity
Clindamycin
DNA pol III
Which end of a growing DNA strand is the target
Higher the cholesterol or long saturated fatty acid content
45. Does not
White codon is at the 3 prime end of a tRNA
Cilia structure
Eukaroytes
polyadenylation does/does not require a template
46. UGA - UAG - UAA
Chloramphenicol
microtubule
mRNA stop codons
Mebendazole/thiabendazole
47. VItamin C
Hereditary non polyposis colorectal cancer
Guanine has a
What does the hydroxylation of proline and lysine require
Smooth ER
48. Neurons - skeletal - and cardiac muscle - RBCs
Example of permanent cells
Alternate splicing
Vincristine/Vinblastine
Alports syndrome
49. Introns stay In the nucleus whereas EXons EXit and are EXpressed
Alports syndrome
Ehlers Danlos
Where do introns and exons stay
RNA polymerases in eukaryotes
50. Exocytose procollagen into extracellylar sace
Outside the cell what processing must be done in procolalgen
tRNA activation
Xeroderma pigmentosum
Excocytosis of collagen