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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Never go to Go divide rapidly with short G1 bone marrow - gut epithelium - skin - hair follicles
Purines
Labile
Higher the cholesterol or long saturated fatty acid content
helicase
2. GTP
Macrolides
promoter
DNA pol I
tRNA gripping and going places
3. Create a nick in the helix to relieve supercoils created during replication
Tetracyclines
DNA topoisomerases
DNA ligase
C- G bond
4. Inhibits bacterials dihydrofolate reducatese down thymine
What ties teh nucleosome together
trimethoprim
cytokeratin
Vincristine/Vinblastine
5. Lysine/hydroxylysine and combines to form collagen
Free ribosomes
Tropocollagen cross links between_____ to form____
Pyrimidines
Vincristine/Vinblastine
6. RNA polymerase I makes rRNA - RNA pol II makes mRNA - RNA pol III makes tRNA
Hydroxylation of which amino acids are attached to Glycine to form collagen
Pyrimidines
RNA polymerases in eukaryotes
Mebendazole/thiabendazole
7. Cylindrical structure composed of helical array of plymerized dimers of alpha and beta tubulin - flagella - cilia - mitotic spindle - grows slowly collapses quickly
6MP
Cell cycle
Outside the cell what processing must be done in procolalgen
microtubule
8. HS1 - HSB - H2 - H4
Excocytosis of collagen
histone octamer names
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
Cell cycle
9. Makes an RNA primer on which DNA polymerase II can initiate replication
Primase
What type of collagen is most affected in Ehlers Danlos
Glycosolation
Step one of RNA processing
10. Prokaryotic only. Elongates leading strand by adding deoxynucleotides to the 3prime end. Elongates laggin strand. 3 prime to 5 prime exonuclease activity
DNA pol III
Protein synthesis initiation
Step Three of RNA processing
Plasma membrane composition
11. Regulatory proteins that control cell cycle events; phase specific; activated CDKs
Sodium K ATPase
6MP
Silencer
Cyclins
12. Greater melting temperature lower fluidity
Alternate splicing
Higher the cholesterol or long saturated fatty acid content
Covalent alterations
The only histone not on the core
13. Stretch of DNA that alters gene expression by binding transcription factors
Functional organization of the gene
the tRNA- amino acid bond
Enhancer
The only histone not on the core
14. Genetic code is conserved throughout evolution
universal
Step one of RNA processing
Order of mitosis
Primase
15. Trimming removal of n or c terminal propeptides from zymogens to generate mature proteinds
Hereditary non polyposis colorectal cancer
mRNA is syntehsized in which direction?
Cell cycle
Post - translational modifications
16. Change resulting in misreading of all nucleotides downstream - usually resulting in a truncated non functional protien
A- T
frame shift
trimethoprim
Tumor Suppressors
17. You glyucosolate hte pro - alpha chain lysine resudens and form procollagen (triple helix of alpha chains)
What ties teh nucleosome together
White codon is at the 3 prime end of a tRNA
Glycosolation
Post - translational modifications
18. 2 H bonds greater GC content greater melting point
DNA/RNA/Protein syntesis direction
A- T
Hereditary non polyposis colorectal cancer
cytokeratin
19. G1 - S - G2 - Mitosis
Euchromatin
Elastin is broken down by
Collagen
Cell cycle order
20. Alpha 1 antitrypisn
single stranded binding proteinds
Eukaroytes
Elastase is inhibited by
mRNA stop codons
21. Tansport cellular cargo toward opposite ends of microtubule tracks
Cyclin - CDK
Molecular motor protiesn
Tropocollagen cross links between_____ to form____
Base excision repair
22. Made from IMP precursor
purines
C- G bond
microtubule
Introns
23. The 5prime end (energy for the bond)
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
Steps in splicing
Which end of the nucleotide has the triphosphate
Prokaryotes
24. Phosphorylation - glycosloation - hyderoxylation
Covalent alterations
Non homologous end joining
Aminoacylt - tRNA synthetase
Osteogenesis Imperfecta
25. Prokaryotic only. Degrades RNA primer and fills in the gap with DNA (5 prime to 3 prime exonuclease)
Chloramphenicol
Which end of a growing DNA strand is the target
Osteogenesis Imperfecta
DNA pol I
26. Unmethylated - newly synthesized string is recognized - mismatched nucleotides are removed and the gap is filled and resealed
helicase
Mismatch repair
DNA/RNA/Protein syntesis direction
Thymine has a
27. Cilia - glagella - mitotic spindle - neurons - centrioles
Exons
microtubule
A- T
Deamination of cytosine makes
28. Nucleotide excision repair - Base Excision repair - Mismath repair
Type IV collagen is an important structural component of...
Single Strand DNA Repair types
Guanine has a
Outside the cell what processing must be done in procolalgen
29. Hydroxy proline and hydroxylysine
Plasma membrane composition
Hydroxylation of which amino acids are attached to Glycine to form collagen
Elastin
Order of mitosis
30. Cyclin depndent kinases; consituative and inactive
Post - translational modifications
tRNA activation
CDKs
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
31. Brings together 2 ends of DNA fragments no requirement for homology
Non homologous end joining
nonsense
Collagen
kinesin
32. Ketone
Guanine has a
the tRNA- amino acid bond
Type IV collagen is an important structural component of...
Cell cycle order
33. AUG inAUGurates protein synthesis
Which end of a growing DNA strand is the target
Collagedn synthesis where?
mRNA start codons
dyenin
34. Microtubule polymerization defect resulting in lowered phagocytosis. results in recurrent pyogenic infections - partial albinism and peripheral neuropathy
Elastin
Chediak Higashi syndrome
Smooth ER
Which end of the tRNA is the amino acid bound to?
35. Elastase
RNA polymerases in eukaryotes
Purines
Elastin is broken down by
Osteogenesis Imperfecta
36. Rampant - Massive - TIny rRNA is most common - then mRNA and then tRNA
Protein synthesis is in which direction
CDKs
capped and tail transcript is called
Which is the most and least abundant type of RNA
37. 9+2 arrangement of microtubules -
Free ribosomes
Cilia structure
Elastase is inhibited by
Proofreading function in eukaryotic RNA
38. Binds 50S blocking translocation
A- T
Clindamycin
purines
Tetracyclines
39. Cleave terminal regions of procollagen to transform into insoluable tropocolagen
tRNA
Outside the cell what processing must be done in procolalgen
Silencer
DNA pol III
40. Xlinked recessive IV collagen bm - kidney - ear and eye -- nephritis and defness ocular disturbances
Alports syndrome
single stranded binding proteinds
Thymine has a
Hereditary non polyposis colorectal cancer
41. Type III
kinesin
Initial transcript without processing is known as
What type of collagen is most affected in Ehlers Danlos
Mismatch repair
42. Specific endonucleases release the oligonucleotide containing damaged bases. DNA polymerase and logase fill and resealt eh gap
microtubule
Prokaryote RNA pol
Nucleotide excision repair
Eukaroytes
43. Inhibits ribonucleotide reductase
Free ribosomes
Methotrexate
hydroxyurea
Going APE
44. Anti cancer - act on microtubules
tRNA Structure
Vincristine/Vinblastine
Digoxin (cardiac glycosides)
Sodium K ATPase
45. A site - incoming aminoacyl tRNA - Psite accomodates growing Peptide - E site holds EmplytRNA as it exits
Immunohistochemical stains vimentin
mRNA is syntehsized in which direction?
Silencer
Going APE
46. The N to C
Protein synthesis is in which direction
Stable (quiescent)
transversion
tRNA Structure
47. Site of secretory protiens (mucus secreting goblet cells and antibody secreting cells)
6MP
origin of replication
Rough ER
mRNA start codons
48. Substituting a pyramidine for a pyrimadine
Cholchicine
Double Strand DNA repair
Deamination of cytosine makes
transition
49. Methionine - which may be removed before translation is completed
Vincristine/Vinblastine
Tropocollagen cross links between_____ to form____
In eukaryotes the starting amino acid is...
Post - translational modifications
50. Base + ribose
commaless - non - overlapping
Griseofulvin
Promoter mutation
nucleosid