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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Cyclin depndent kinases; consituative and inactive
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
Non homologous end joining
Cyclins
CDKs
2. In the nucleus after transcitpion and only processed RNA is transporte out of the nucleus
What does the hydroxylation of proline and lysine require
RNA processing in eukaryotes occurs
Tropocollagen cross links between_____ to form____
frame shift
3. Has enough energy to created the peptide bond
Double Strand DNA repair
Cyclins
Kartageners syndrome
the tRNA- amino acid bond
4. Inhibits by binding to the potassium side
Oubain
Aminoglycosides
microtubule
Non homologous end joining
5. Contain the actual genetic information coding for protein
Kartageners syndrome
Permanent cells
Exons
methionine is only encoded by
6. Same aa often base change in 3rd position of codon
silent mutation
the tRNA- amino acid bond
GFAP
Cell cycle
7. (A - G) 2 rings Pure As Gold
Exons
Aminoacylt - tRNA synthetase
Purines
mRNA start codons
8. Base+ribose+phosphate linked by a phosphodiester bond
nucleotide
Excocytosis of collagen
unambiguous
Single Strand DNA Repair types
9. Binds 50S blocking translocation
Termination
Clindamycin
Exons
transversion
10. A malfunction of mismatch repair (MUt L etc..)
Hereditary non polyposis colorectal cancer
Chloramphenicol
tRNA Structure
mRNA is syntehsized in which direction?
11. Trimming removal of n or c terminal propeptides from zymogens to generate mature proteinds
Base excision repair
histone octamer names
nucleosid
Post - translational modifications
12. Bind 50S blocking translocation
Glycosolation
promoter
Macrolides
chromatin structure
13. Changed aaconservative - new aa is similar in chemical structure
missense mutation
step two of RNA processing
desmin
Primase
14. Exocytose procollagen into extracellylar sace
Tetracyclines
missense mutation
Excocytosis of collagen
C- G bond
15. Base + ribose
Deamination of cytosine makes
universal
Cyclins
nucleosid
16. Inhibits 50S peptidyl transferase
Pyrimidines
Chloramphenicol
Associations of Ehlers Danlos
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
17. Nucleotide excision repair - Base Excision repair - Mismath repair
nonsense
Single Strand DNA Repair types
AUG codes For what in prokaryotes
CDKs
18. GTP
Digoxin (cardiac glycosides)
tRNA gripping and going places
Termination
Chloramphenicol
19. Y shaped region along DNA template where leading and lagging strands are syntehsized
degenerate or redundant
Replication fork
intermediate filaments
Nucleotide excision repair
20. 75-90 nucleotides - 2ary structure cloverleaf form anticodon end is opposite 3 prime aminoacyl end
Gag on pure gold
tRNA Structure
Fluoroquinolones
Which end of a growing DNA strand is the target
21. Site where RNA polymerase and multiple other transciption factors bind to DNA upstream from gene locus (AT rich upstream sequence with TATA and CAAT boxes)
Labile
Mebendazole/thiabendazole
Ehlers Danlos
promoter
22. Each codon specifies only 1 amino acid
unambiguous
Cyclin - CDK
Euchromatin
Neurofilaments
23. Less condensed - transciptionally active=eu truly transcobed
Promoter mutation
Euchromatin
Protein synthesis is in which direction
Glycosolation
24. Microtubule polymerization defect resulting in lowered phagocytosis. results in recurrent pyogenic infections - partial albinism and peripheral neuropathy
tRNA
Chediak Higashi syndrome
Vincristine/Vinblastine
unambiguous
25. Rampant - Massive - TIny rRNA is most common - then mRNA and then tRNA
Eukaroytes
Cholchicine
Collagedn synthesis where?
Which is the most and least abundant type of RNA
26. Substituting a pyramidine for a pyrimadine
Cyclin - CDK
Thymine has a
Termination
transition
27. Anti cancer - act on microtubules
Cyclin - CDK
Axonemal dyenin
Paclitaxil
Vincristine/Vinblastine
28. Be So Totatally Cool Read Books (bOne - CarTWOlage - Threeticular - Type IV under the floor)
Collagen
Plasma membrane composition
Aminoacylt - tRNA synthetase
Single Strand DNA Repair types
29. The 3 prime hydroxyl of the nascent chain is the target
pyrimadines
What type of collagen is most affected in Ehlers Danlos
Which end of a growing DNA strand is the target
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
30. Condensed - transciptionally inactive HC- Highly condensed
Heterochromatin
nucleosid
Rough ER
Collagen
31. Vimentin - desmin - cytockeratin - glial fibrillary acid proteins - neurofilaments
Clindamycin
Immunohistochemical stains vimentin
intermediate filaments
Associations of Ehlers Danlos
32. Uracil
frame shift
Deamination of cytosine makes
Alports syndrome
Nucleotide excision repair
33. Type III
Kartageners syndrome
purines
What type of collagen is most affected in Ehlers Danlos
Protein synthesis is in which direction
34. Prokaryotic only. Elongates leading strand by adding deoxynucleotides to the 3prime end. Elongates laggin strand. 3 prime to 5 prime exonuclease activity
Initial transcript without processing is known as
C- G bond
DNA pol III
tRNA
35. Promoter - enhancer - promoter - TATA- transcription initiation site - coding region (including exons and introns) and then the AATAAA
nonsense
the tRNA- amino acid bond
Double Strand DNA repair
Functional organization of the gene
36. Codes for formyl methionine (f - Met)
Proteosomal degradation
Smooth ER
AUG codes For what in prokaryotes
What does the hydroxylation of proline and lysine require
37. Genetic code is conserved throughout evolution
origin of replication
Hydroxylation of which amino acids are attached to Glycine to form collagen
universal
tRNA activation
38. Cleave terminal regions of procollagen to transform into insoluable tropocolagen
Chloramphenicol
tRNA aminoacylation
Outside the cell what processing must be done in procolalgen
Paclitaxil
39. Connective tissue
Immunohistochemical stains vimentin
Elastase is inhibited by
White codon is at the 3 prime end of a tRNA
kinesin
40. Elastase
Elastin is broken down by
Going APE
Associations of Ehlers Danlos
Replication fork
41. Stretch of DNA that alters gene expression by binding transcription factors
Collagedn synthesis where?
Enhancer
Collagen
frame shift
42. Activated by GTP hydrolosis initiation factors help assembel the 40 S ribosomal subunites with the initiatior tRNA and are released whent he mRNA and the ribosomal subunit assemple with the complex
Protein synthesis initiation
Post - translational modifications
RNA polymerases in eukaryotes
Pyrimidines
43. Neuroglia
GFAP
Step one of RNA processing
Macrolides
Prokaryote RNA pol
44. Muscle
Which end of a growing DNA strand is the target
silent mutation
desmin
universal
45. Made from orogate precuror with PRPP added later
pyrimadines
The only histone not on the core
AUG codes For what in prokaryotes
Post - translational modifications
46. Genetic bone disorder (brittle bone disease) type 1 colalgen - fractures (during birth) 2) Blue sclerae 3) hearing loss 4) dental imperfections 1:10000 may be confused with child abuse
tRNA aminoacylation
Osteogenesis Imperfecta
Exons
Prokaryotes
47. Seals
Which end of the tRNA is the amino acid bound to?
Chediak Higashi syndrome
DNA ligase
Guanine has a
48. Immotile cilia due to a dyenin arm defect. Results in male nad female inferticility (sperm immotile) - bronchiectasis - and recurrent sinusisits - associated with situs inversus
Alternate splicing
Where do introns and exons stay
cytokeratin
Kartageners syndrome
49. Aminoacyl - tRNA binds to A site 2) peptidyltransferase catalyzes peptide bond formation transfers growing polypeptie to amino acid in A site 3) ribosome advances 3 nucleotides toward the 3 prime end of RNA moving peptiydyl RNA to P site
Silencer
desmin
histone octamer names
Elongation
50. ATP ase that links peripheral 9 doublets and causes bending of cilium by differential sliding of doublets
Axonemal dyenin
Collagedn synthesis where?
step two of RNA processing
6MP