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First Aid: Biochemistry Molecular

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Retrograde to microtubules






2. HS1 - HSB - H2 - H4






3. Immotile cilia due to a dyenin arm defect. Results in male nad female inferticility (sperm immotile) - bronchiectasis - and recurrent sinusisits - associated with situs inversus






4. Inhibit DNA gyrase (specific prokaryotic topoisomerase)






5. Genetic code is conserved throughout evolution






6. 3 sodium out for 2 potassium in (nout - kin)takes 1 atp and the machine is phosphorylated during the machine cycle






7. Cyclin depndent kinases; consituative and inactive






8. Methyl THYmine has a meTHYl






9. Introns stay In the nucleus whereas EXons EXit and are EXpressed






10. More than 1 codon may code for the same amino acid






11. 1) primary transcript combines with snRNPs and other proteins to form spliceosome 2) lariat shaped intermediate is generated 3) Lariat is removed and released to precisely join 2 exons






12. Base + ribose






13. Trimming removal of n or c terminal propeptides from zymogens to generate mature proteinds






14. Microtubule polymerization defect resulting in lowered phagocytosis. results in recurrent pyogenic infections - partial albinism and peripheral neuropathy






15. Alpha 1 antitrypisn






16. The N to C






17. Same aa often base change in 3rd position of codon






18. Site where RNA polymerase and multiple other transciption factors bind to DNA upstream from gene locus (AT rich upstream sequence with TATA and CAAT boxes)






19. Made from IMP precursor






20. 1 RNA polymerase (multisubunite complex) makes all 3 kinds of RNA






21. Cylindrical structure composed of helical array of plymerized dimers of alpha and beta tubulin - flagella - cilia - mitotic spindle - grows slowly collapses quickly






22. Hydroxy proline and hydroxylysine






23. Strethchy protein within lungs - large artiers - elastic liaments - vocal cords - ligamenta flava)






24. UGA - UAG - UAA






25. Completed protein is released from ribosme through simple hydrolosis and dissociates






26. Type III






27. 1P (blocked by tetracycline)






28. ATP






29. Faulty collagen synthesis causing 1) hyperextensible skin 2) tendency to bleed 3) hypermobile joints






30. Muscle






31. Anit helminth - act on microtubules






32. Genetic bone disorder (brittle bone disease) type 1 colalgen - fractures (during birth) 2) Blue sclerae 3) hearing loss 4) dental imperfections 1:10000 may be confused with child abuse






33. Anterograde to microtubule






34. Each codon specifies only 1 amino acid






35. Inhibits the atpase which increases intracellular sodium which increases intracellular calcium increases cardiaccontractility






36. 1P blocked by chloramphenicaol and macrolide






37. P53 and RB normally inhibit g1 to S progression






38. Specific glycosylases recognize and remove damaged bases - AP endonuclease cuts DNA at pyrimidne site - empty sugar is removed and the gap is filled and resealed






39. One codon AUG






40. Xlinked recessive IV collagen bm - kidney - ear and eye -- nephritis and defness ocular disturbances






41. ATP- AMP (2 phosphoanhydride bonds)






42. Has enough energy to created the peptide bond






43. Anti breast cancer - acts on mts






44. 2 H bonds greater GC content greater melting point






45. Seals






46. Unattached to any membrane; site of cytosolic and organeller prtoeins






47. Nucleotide excision repair - Base Excision repair - Mismath repair






48. Inhbits RNA pol II (found in death cap mushrooms)






49. Asymmetric fluid bilayer - contains - cholesterol - phospholipids - sphingoplipids - glycolipids - and protiends






50. Hn RNA