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First Aid: Biochemistry Molecular

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Accurate base pairing is required only in the first 2 nucleotide positions of an mRNA so codons differing ht e3rd wobble psoition may code for the same tRNA/amino acid code






2. RNA polymerase I makes rRNA - RNA pol II makes mRNA - RNA pol III makes tRNA






3. Microvilli - muscle contraction - cytokinesis - adhering juntions






4. Scrutinizes aa before and after it binds to tRNA. If incorrect bond is hydrolyzed.






5. Stretch of DNA that alters gene expression by binding transcription factors






6. Seals






7. MRNA






8. Uracil






9. Never go to Go divide rapidly with short G1 bone marrow - gut epithelium - skin - hair follicles






10. Cleave terminal regions of procollagen to transform into insoluable tropocolagen






11. Attachment of ubiquitin to defective proteinds to tag them for breakdown






12. 3 H bonds






13. Rampant - Massive - TIny rRNA is most common - then mRNA and then tRNA






14. Substituting a purine for a pyrimdine or vice versa






15. HS1 - HSB - H2 - H4






16. Odd 30S plus 50 S=70S






17. Remain in G0 regenerate from stem cells






18. Lysine/hydroxylysine and combines to form collagen






19. Inhibit DNA gyrase (specific prokaryotic topoisomerase)






20. Methionine - which may be removed before translation is completed






21. Prokaryotic only. Elongates leading strand by adding deoxynucleotides to the 3prime end. Elongates laggin strand. 3 prime to 5 prime exonuclease activity






22. Intervening noncoding segments of DNA






23. Inhibits thymidylate synthase down thymine






24. Xlinked recessive IV collagen bm - kidney - ear and eye -- nephritis and defness ocular disturbances






25. Genetic bone disorder (brittle bone disease) type 1 colalgen - fractures (during birth) 2) Blue sclerae 3) hearing loss 4) dental imperfections 1:10000 may be confused with child abuse






26. H1






27. Capping on 5 prime end (7 methylguanosine) -






28. 9+2 arrangement of microtubules -






29. ATP ase that links peripheral 9 doublets and causes bending of cilium by differential sliding of doublets






30. UGA - UAG - UAA






31. Anti cancer - act on microtubules






32. 5 prime to 3 prime






33. Must be both activated and inactivated for cell cycle to progress






34. Close to - far from or even within (in an intron) the gene whose expression it regulates






35. RER translation of collagen alpha chains (preprocollagen) usually Gly-X-Y






36. Activated by GTP hydrolosis initiation factors help assembel the 40 S ribosomal subunites with the initiatior tRNA and are released whent he mRNA and the ribosomal subunit assemple with the complex






37. 2 H bonds greater GC content greater melting point






38. Elastase






39. 1) primary transcript combines with snRNPs and other proteins to form spliceosome 2) lariat shaped intermediate is generated 3) Lariat is removed and released to precisely join 2 exons






40. Proline - glycine






41. Inhibits the atpase which increases intracellular sodium which increases intracellular calcium increases cardiaccontractility






42. Vimentin - desmin - cytockeratin - glial fibrillary acid proteins - neurofilaments






43. CUT 1 ring Cut the Py






44. AD and AR- associated iwth joint dislocation - berry aneurysms - organ rupture






45. Negatively charged DNA loops twice around histone octamers create a nucloesome bead.






46. Site where negative regulators bind






47. Does not






48. Faulty collagen synthesis causing 1) hyperextensible skin 2) tendency to bleed 3) hypermobile joints






49. Cilia - glagella - mitotic spindle - neurons - centrioles






50. Changed aaconservative - new aa is similar in chemical structure