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First Aid: Biochemistry Molecular

Instructions:
  • Answer 50 questions in 15 minutes.
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  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Inhibits 50S peptidyl transferase






2. DNA And RNA synthesized in the 5-3 direction






3. Immotile cilia due to a dyenin arm defect. Results in male nad female inferticility (sperm immotile) - bronchiectasis - and recurrent sinusisits - associated with situs inversus






4. ATP






5. Neurons






6. Site where negative regulators bind






7. Specific glycosylases recognize and remove damaged bases - AP endonuclease cuts DNA at pyrimidne site - empty sugar is removed and the gap is filled and resealed






8. Bind 50S blocking translocation






9. Muscle






10. Aminoacyl - tRNA binds to A site 2) peptidyltransferase catalyzes peptide bond formation transfers growing polypeptie to amino acid in A site 3) ribosome advances 3 nucleotides toward the 3 prime end of RNA moving peptiydyl RNA to P site






11. Bind 30S subunit preventing attachment of aminoacyl - tRNA






12. 3 sodium out for 2 potassium in (nout - kin)takes 1 atp and the machine is phosphorylated during the machine cycle






13. Specific endonucleases release the oligonucleotide containing damaged bases. DNA polymerase and logase fill and resealt eh gap






14. Antigout - acts on mts






15. A site - incoming aminoacyl tRNA - Psite accomodates growing Peptide - E site holds EmplytRNA as it exits






16. 75-90 nucleotides - 2ary structure cloverleaf form anticodon end is opposite 3 prime aminoacyl end






17. ATP- AMP (2 phosphoanhydride bonds)






18. Methionine - which may be removed before translation is completed






19. (A - G) 2 rings Pure As Gold






20. Neurons - skeletal - and cardiac muscle - RBCs






21. Attachment of ubiquitin to defective proteinds to tag them for breakdown






22. Prokaryotic only. Degrades RNA primer and fills in the gap with DNA (5 prime to 3 prime exonuclease)






23. No proofreading function but can initiate chains. RNA poymerase II opens DNA at promoter site






24. Odd 30S plus 50 S=70S






25. 1) primary transcript combines with snRNPs and other proteins to form spliceosome 2) lariat shaped intermediate is generated 3) Lariat is removed and released to precisely join 2 exons






26. Inhibits ribonucleotide reductase






27. Site of dteroid synthesis and detoxification of druigs and poisons (liver hepatocytes and steroid horomore adrenal cortex)






28. 2 H bonds greater GC content greater melting point






29. H1 string






30. Microtubule polymerization defect resulting in lowered phagocytosis. results in recurrent pyogenic infections - partial albinism and peripheral neuropathy






31. Hydroxy proline and hydroxylysine






32. Codes for formyl methionine (f - Met)






33. Ribonucleotide reductase






34. You glyucosolate hte pro - alpha chain lysine resudens and form procollagen (triple helix of alpha chains)






35. G1 - S - G2 - Mitosis






36. CUT 1 ring Cut the Py






37. Site where RNA polymerase and multiple other transciption factors bind to DNA upstream from gene locus (AT rich upstream sequence with TATA and CAAT boxes)






38. Binds 50S blocking translocation






39. Type III






40. Cylindrical structure composed of helical array of plymerized dimers of alpha and beta tubulin - flagella - cilia - mitotic spindle - grows slowly collapses quickly






41. Exocytose procollagen into extracellylar sace






42. Blocks denovo purine synthesis






43. Made from orogate precuror with PRPP added later






44. Cyclin depndent kinases; consituative and inactive






45. Genetic code is conserved throughout evolution






46. Never go to Go divide rapidly with short G1 bone marrow - gut epithelium - skin - hair follicles






47. Close to - far from or even within (in an intron) the gene whose expression it regulates






48. Microvilli - muscle contraction - cytokinesis - adhering juntions






49. RER translation of collagen alpha chains (preprocollagen) usually Gly-X-Y






50. Neuroglia







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