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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Made from orogate precuror with PRPP added later
the tRNA- amino acid bond
pyrimadines
Which end of a growing DNA strand is the target
Cyclins
2. Cyclin depndent kinases; consituative and inactive
CDKs
commaless - non - overlapping
Chloramphenicol
Oubain
3. More than 1 codon may code for the same amino acid
Molecular motor protiesn
purines
degenerate or redundant
Aminoacylt - tRNA synthetase
4. P53 and RB normally inhibit g1 to S progression
Tumor Suppressors
Protein synthesis is in which direction
Primase
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
5. ATP- AMP (2 phosphoanhydride bonds)
Pyrimidines
tRNA aminoacylation
Vincristine/Vinblastine
tRNA gripping and going places
6. In the nucleus after transcitpion and only processed RNA is transporte out of the nucleus
Covalent alterations
RNA processing in eukaryotes occurs
Cholchicine
microtubule
7. 1 RNA polymerase (multisubunite complex) makes all 3 kinds of RNA
histone octamer names
Elongation
Prokaryote RNA pol
Guanine has a
8. Greater melting temperature lower fluidity
Paclitaxil
The only histone not on the core
Sodium K ATPase
Higher the cholesterol or long saturated fatty acid content
9. Bind 30S subunit preventing attachment of aminoacyl - tRNA
Heterochromatin
Griseofulvin
DNA/RNA/Protein syntesis direction
Tetracyclines
10. Asymmetric fluid bilayer - contains - cholesterol - phospholipids - sphingoplipids - glycolipids - and protiends
Eukaroytes
capped and tail transcript is called
Proteosomal degradation
Plasma membrane composition
11. Capping on 5 prime end (7 methylguanosine) -
the tRNA- amino acid bond
What ties teh nucleosome together
Step one of RNA processing
Non homologous end joining
12. Y shaped region along DNA template where leading and lagging strands are syntehsized
Replication fork
Example of permanent cells
The only histone not on the core
Axonemal dyenin
13. Seals
DNA ligase
Excocytosis of collagen
Single Strand DNA Repair types
Prokaryotes
14. Inhbits RNA pol II (found in death cap mushrooms)
alpha amintin
Immunohistochemical stains vimentin
purines
Griseofulvin
15. Contain the actual genetic information coding for protein
DNA topoisomerases
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
Gag on pure gold
Exons
16. Connective tissue
Immunohistochemical stains vimentin
Tetracyclines
transversion
chromatin structure
17. Has enough energy to created the peptide bond
Base excision repair
commaless - non - overlapping
Aminoacylt - tRNA synthetase
the tRNA- amino acid bond
18. The 5prime end (energy for the bond)
Hydroxylation of which amino acids are attached to Glycine to form collagen
Chloramphenicol
Which end of the nucleotide has the triphosphate
alpha amintin
19. GTP
capped and tail transcript is called
tRNA gripping and going places
Alports syndrome
Proteosomal degradation
20. Ribonucleotide reductase
Alternate splicing
Steps in splicing
Prokaryote RNA pol
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
21. Enter G1 from G0 when stimulated Hepatocytes/lymphocytes
Methotrexate
intermediate filaments
Which end of the nucleotide has the triphosphate
Stable (quiescent)
22. Activated by GTP hydrolosis initiation factors help assembel the 40 S ribosomal subunites with the initiatior tRNA and are released whent he mRNA and the ribosomal subunit assemple with the complex
Alternate splicing
AUG codes For what in prokaryotes
Protein synthesis initiation
5FU
23. Less condensed - transciptionally active=eu truly transcobed
Silencer
Nucleotide excision repair
Euchromatin
Plasma membrane composition
24. Site where RNA polymerase and multiple other transciption factors bind to DNA upstream from gene locus (AT rich upstream sequence with TATA and CAAT boxes)
promoter
Clindamycin
Termination
C- G bond
25. Strethchy protein within lungs - large artiers - elastic liaments - vocal cords - ligamenta flava)
Plasma membrane composition
Macrolides
Elastin
Glycosolation
26. Change resulting in misreading of all nucleotides downstream - usually resulting in a truncated non functional protien
Which is the most and least abundant type of RNA
frame shift
Chloramphenicol
Alternate splicing
27. Binds 50S blocking translocation
Axonemal dyenin
Clindamycin
alpha amintin
Permanent cells
28. Negatively charged DNA loops twice around histone octamers create a nucloesome bead.
Paclitaxil
CDKs
promoter
chromatin structure
29. ATP ase that links peripheral 9 doublets and causes bending of cilium by differential sliding of doublets
Cyclin - CDK
commaless - non - overlapping
Axonemal dyenin
intermediate filaments
30. Poly adenylation
dyenin
step two of RNA processing
Hydroxylation of which amino acids are attached to Glycine to form collagen
DNA pol III
31. UGA - UAG - UAA
Termination
mRNA stop codons
The only histone not on the core
Alternate splicing
32. Rampant - Massive - TIny rRNA is most common - then mRNA and then tRNA
Axonemal dyenin
Plasma membrane composition
Which is the most and least abundant type of RNA
What does the hydroxylation of proline and lysine require
33. Exocytose procollagen into extracellylar sace
Xeroderma pigmentosum
Excocytosis of collagen
mRNA is syntehsized in which direction?
Proteosomal degradation
34. Inhibits the atpase which increases intracellular sodium which increases intracellular calcium increases cardiaccontractility
Digoxin (cardiac glycosides)
unambiguous
frame shift
Tumor Suppressors
35. Muscle
Plasma membrane composition
Paclitaxil
desmin
Vincristine/Vinblastine
36. Remain in G0 regenerate from stem cells
kinesin
CDKs
Permanent cells
Elastin is broken down by
37. Specific glycosylases recognize and remove damaged bases - AP endonuclease cuts DNA at pyrimidne site - empty sugar is removed and the gap is filled and resealed
Base excision repair
A- T
Step Three of RNA processing
Purines
38. Completed protein is released from ribosme through simple hydrolosis and dissociates
Termination
Kartageners syndrome
Rough ER
Neurofilaments
39. Inhibits bacterials dihydrofolate reducatese down thymine
Base excision repair
C- G bond
Purines
trimethoprim
40. Inhibits dihydrofolate reductase down thymine
Where do introns and exons stay
Methotrexate
Macrolides
Mebendazole/thiabendazole
41. Inhibits 50S peptidyl transferase
Chloramphenicol
Example of permanent cells
Enhancer
desmin
42. Substituting a purine for a pyrimdine or vice versa
cytokeratin
transversion
tRNA activation
dyenin
43. Cylindrical structure composed of helical array of plymerized dimers of alpha and beta tubulin - flagella - cilia - mitotic spindle - grows slowly collapses quickly
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
Promoter mutation
microtubule
unambiguous
44. Unmethylated - newly synthesized string is recognized - mismatched nucleotides are removed and the gap is filled and resealed
Functional organization of the gene
Mismatch repair
Clindamycin
Nucleotide excision repair
45. Be So Totatally Cool Read Books (bOne - CarTWOlage - Threeticular - Type IV under the floor)
Cyclin - CDK
Enhancers and silencer may be located_____
Collagen
CDKs
46. One codon AUG
tRNA gripping and going places
Cell cycle
single stranded binding proteinds
methionine is only encoded by
47. Accurate base pairing is required only in the first 2 nucleotide positions of an mRNA so codons differing ht e3rd wobble psoition may code for the same tRNA/amino acid code
Introns
C- G bond
Cilia structure
tRNA
48. Non homologous end joining
Double Strand DNA repair
degenerate or redundant
nonsense
missense mutation
49. Inhibits thymidylate synthase down thymine
5FU
Aminoglycosides
Tumor Suppressors
mRNA stop codons
50. Intervening noncoding segments of DNA
microtubule
Cyclins
Hereditary non polyposis colorectal cancer
Introns