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First Aid: Biochemistry Molecular

Subjects : health-sciences, first-aid

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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1. Each codon specifies only 1 amino acid
Stable (quiescent)
Collagedn synthesis where?
unambiguous
kinesin

2. CUT 1 ring Cut the Py
Pyrimidines
5FU
tRNA Structure
Permanent cells

3. Completed protein is released from ribosme through simple hydrolosis and dissociates
Elastin
DNA ligase
Termination
Introns

4. Site where negative regulators bind
the tRNA- amino acid bond
Silencer
Step Three of RNA processing
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by

5. GTP
capped and tail transcript is called
Which is the most and least abundant type of RNA
trimethoprim
tRNA gripping and going places

6. Substituting a purine for a pyrimdine or vice versa
Functional organization of the gene
transversion
Post - translational modifications
Immunohistochemical stains vimentin

7. Enter G1 from G0 when stimulated Hepatocytes/lymphocytes
Pyrimidines
Associations of Ehlers Danlos
Stable (quiescent)
Non homologous end joining

8. Inhibits dihydrofolate reductase down thymine
Methotrexate
Primase
transition
Covalent alterations

9. Attachment of ubiquitin to defective proteinds to tag them for breakdown
Post - translational modifications
tRNA aminoacylation
mRNA start codons
Proteosomal degradation

10. Prokaryotic only. Degrades RNA primer and fills in the gap with DNA (5 prime to 3 prime exonuclease)
Mebendazole/thiabendazole
DNA pol I
Exons
Gag on pure gold

11. Promoter - enhancer - promoter - TATA- transcription initiation site - coding region (including exons and introns) and then the AATAAA
DNA ligase
Functional organization of the gene
Translocation
Hydroxylation of which amino acids are attached to Glycine to form collagen

12. Bind 50S blocking translocation
Cell cycle order
Collagedn synthesis where?
Macrolides
Introns

13. Checkpoints control transition between phases of cell cycle. regulated by cyclins - CDKs and tumor suppressors. Mitosis (shortest phse)
Replication fork
Rough ER
Free ribosomes
Cell cycle

14. MRNA
capped and tail transcript is called
Single Strand DNA Repair types
Exons
pyrimadines

15. Anterograde to microtubule
Outside the cell what processing must be done in procolalgen
Fluoroquinolones
kinesin
C- G bond

16. UGA - UAG - UAA
Associations of Ehlers Danlos
Glycosolation
Post - translational modifications
mRNA stop codons

17. The N to C
Protein synthesis is in which direction
Associations of Ehlers Danlos
Neurofilaments
Digoxin (cardiac glycosides)

18. Stretch of DNA that alters gene expression by binding transcription factors
Type IV collagen is an important structural component of...
microtubule
degenerate or redundant
Enhancer

19. Made from orogate precuror with PRPP added later
Ehlers Danlos
pyrimadines
Stable (quiescent)
microtubule

20. Unmethylated - newly synthesized string is recognized - mismatched nucleotides are removed and the gap is filled and resealed
Osteogenesis Imperfecta
microtubule
Enhancers and silencer may be located_____
Mismatch repair

21. Create a nick in the helix to relieve supercoils created during replication
helicase
DNA topoisomerases
Sodium K ATPase
Which end of a growing DNA strand is the target

22. Genetic bone disorder (brittle bone disease) type 1 colalgen - fractures (during birth) 2) Blue sclerae 3) hearing loss 4) dental imperfections 1:10000 may be confused with child abuse
Axonemal dyenin
Osteogenesis Imperfecta
CDKs
Exons

23. Site where RNA polymerase and multiple other transciption factors bind to DNA upstream from gene locus (AT rich upstream sequence with TATA and CAAT boxes)
the tRNA- amino acid bond
promoter
DNA topoisomerases
Prokaryotes

24. The 3 prime hydroxyl of the nascent chain is the target
Which end of a growing DNA strand is the target
Alports syndrome
Clindamycin
Tetracyclines

25. H1
Permanent cells
Collagen
The only histone not on the core
Kartageners syndrome

26. Binds 50S blocking translocation
Clindamycin
AUG codes For what in prokaryotes
hydroxyurea
Enhancer

27. Hydroxy proline and hydroxylysine
What ties teh nucleosome together
Hydroxylation of which amino acids are attached to Glycine to form collagen
Going APE
silent mutation

28. Accurate base pairing is required only in the first 2 nucleotide positions of an mRNA so codons differing ht e3rd wobble psoition may code for the same tRNA/amino acid code
DNA pol III
tRNA
pyrimadines
Protein synthesis initiation

29. The 3 prime end
Which end of the tRNA is the amino acid bound to?
silent mutation
Base excision repair
transversion

30. Exocytose procollagen into extracellylar sace
Cilia structure
Excocytosis of collagen
Which end of the tRNA is the amino acid bound to?
DNA pol I

31. Site of secretory protiens (mucus secreting goblet cells and antibody secreting cells)
Total energy expenditure requirement for translocation
Rough ER
Ehlers Danlos
Oubain

32. Change resulting in early stop codon
Order of mitosis
actin and myosin
Promoter mutation
nonsense

33. Changed aaconservative - new aa is similar in chemical structure
Step one of RNA processing
transition
missense mutation
methionine is only encoded by

34. 1P (blocked by tetracycline)
Prokaryotes
Elongation
6MP
Loading tRNA on to ribosome energy requirement

35. Scrutinizes aa before and after it binds to tRNA. If incorrect bond is hydrolyzed.
Example of permanent cells
Aminoacylt - tRNA synthetase
frame shift
Type IV collagen is an important structural component of...

36. In the nucleus after transcitpion and only processed RNA is transporte out of the nucleus
Tetracyclines
Protein synthesis initiation
RNA processing in eukaryotes occurs
Aminoglycosides

37. Base+ribose+phosphate linked by a phosphodiester bond
Osteogenesis Imperfecta
Common amino acids in elastin
Cell cycle order
nucleotide

38. Greater melting temperature lower fluidity
single stranded binding proteinds
Higher the cholesterol or long saturated fatty acid content
Enhancers and silencer may be located_____
Mismatch repair

39. Never go to Go divide rapidly with short G1 bone marrow - gut epithelium - skin - hair follicles
Griseofulvin
Proofreading function in eukaryotic RNA
Labile
Deamination of cytosine makes

40. 2 H bonds greater GC content greater melting point
Which end of a growing DNA strand is the target
A- T
DNA ligase
hydroxyurea

41. Cyclin depndent kinases; consituative and inactive
Mebendazole/thiabendazole
mRNA start codons
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
CDKs

42. Unattached to any membrane; site of cytosolic and organeller prtoeins
Tumor Suppressors
CDKs
Associations of Ehlers Danlos
Free ribosomes

43. The 5prime end (energy for the bond)
Which end of the nucleotide has the triphosphate
capped and tail transcript is called
cytokeratin
Initial transcript without processing is known as

44. Bind 30S subunit preventing attachment of aminoacyl - tRNA
trimethoprim
Nucleotide excision repair
Promoter mutation
Tetracyclines

45. A malfunction of mismatch repair (MUt L etc..)
Hereditary non polyposis colorectal cancer
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
What ties teh nucleosome together
Which end of the nucleotide has the triphosphate

46. Inhibits bacterials dihydrofolate reducatese down thymine
Protein synthesis is in which direction
nucleosid
Primase
trimethoprim

47. Inhibits thymidylate synthase down thymine
Common amino acids in elastin
5FU
Neurofilaments
Cell cycle

48. Prophas - metaphase - anaphase telophase
Order of mitosis
Paclitaxil
Where do introns and exons stay
hydroxyurea

49. Neurons - skeletal - and cardiac muscle - RBCs
Tropocollagen cross links between_____ to form____
Example of permanent cells
intermediate filaments
Eukaroytes

50. Unwinds DNA template at replication fork
The only histone not on the core
Macrolides
DNA pol III
helicase

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First Aid: Biochemistry Molecular

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