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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Seals
Cyclins
DNA ligase
Which is the most and least abundant type of RNA
Enhancers and silencer may be located_____
2. 1 RNA polymerase (multisubunite complex) makes all 3 kinds of RNA
transversion
Mismatch repair
Prokaryote RNA pol
tRNA Structure
3. Xlinked recessive IV collagen bm - kidney - ear and eye -- nephritis and defness ocular disturbances
Alports syndrome
Functional organization of the gene
tRNA gripping and going places
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
4. Connective tissue
Heterochromatin
commaless - non - overlapping
Immunohistochemical stains vimentin
Macrolides
5. Uracil
Deamination of cytosine makes
silent mutation
the tRNA- amino acid bond
Replication fork
6. Poly adenylation
microtubule
What ties teh nucleosome together
unambiguous
step two of RNA processing
7. Scrutinizes aa before and after it binds to tRNA. If incorrect bond is hydrolyzed.
Aminoacylt - tRNA synthetase
Glycosolation
missense mutation
Tropocollagen cross links between_____ to form____
8. CCA AT 3 PRIME END
Aminoacylt - tRNA synthetase
White codon is at the 3 prime end of a tRNA
capped and tail transcript is called
Double Strand DNA repair
9. Change resulting in misreading of all nucleotides downstream - usually resulting in a truncated non functional protien
Step one of RNA processing
Proofreading function in eukaryotic RNA
frame shift
Higher the cholesterol or long saturated fatty acid content
10. 3 H bonds
Chediak Higashi syndrome
C- G bond
Elongation
GFAP
11. The 3 prime hydroxyl of the nascent chain is the target
RNA processing in eukaryotes occurs
Which end of a growing DNA strand is the target
Chediak Higashi syndrome
Covalent alterations
12. Retrograde to microtubules
Clindamycin
Cyclins
nucleotide
dyenin
13. 3 sodium out for 2 potassium in (nout - kin)takes 1 atp and the machine is phosphorylated during the machine cycle
Sodium K ATPase
Common amino acids in elastin
The only histone not on the core
DNA ligase
14. Strethchy protein within lungs - large artiers - elastic liaments - vocal cords - ligamenta flava)
single stranded binding proteinds
Vincristine/Vinblastine
Elastin
Ehlers Danlos
15. Prevents stranges from reannealing
What does the hydroxylation of proline and lysine require
single stranded binding proteinds
What type of collagen is most affected in Ehlers Danlos
Immunohistochemical stains vimentin
16. DNA And RNA synthesized in the 5-3 direction
Where do introns and exons stay
DNA/RNA/Protein syntesis direction
Molecular motor protiesn
silent mutation
17. Base + ribose
Cyclin - CDK
Step one of RNA processing
nucleosid
Free ribosomes
18. Phosphorylation - glycosloation - hyderoxylation
Collagedn synthesis where?
Covalent alterations
GFAP
Neurofilaments
19. Prokaryotic only. Degrades RNA primer and fills in the gap with DNA (5 prime to 3 prime exonuclease)
RNA processing in eukaryotes occurs
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
Higher the cholesterol or long saturated fatty acid content
DNA pol I
20. 1) primary transcript combines with snRNPs and other proteins to form spliceosome 2) lariat shaped intermediate is generated 3) Lariat is removed and released to precisely join 2 exons
Steps in splicing
Example of permanent cells
Cell cycle
Covalent alterations
21. 4 high enrgy bonds
Total energy expenditure requirement for translocation
helicase
Which end of the tRNA is the amino acid bound to?
Proofreading function in eukaryotic RNA
22. You glyucosolate hte pro - alpha chain lysine resudens and form procollagen (triple helix of alpha chains)
Glycosolation
Example of permanent cells
Collagen
A- T
23. Hydroxy proline and hydroxylysine
tRNA Structure
nucleosid
mRNA start codons
Hydroxylation of which amino acids are attached to Glycine to form collagen
24. Methionine - which may be removed before translation is completed
Osteogenesis Imperfecta
In eukaryotes the starting amino acid is...
Sodium K ATPase
Paclitaxil
25. Specific glycosylases recognize and remove damaged bases - AP endonuclease cuts DNA at pyrimidne site - empty sugar is removed and the gap is filled and resealed
Primase
Base excision repair
transition
Prokaryotes
26. Contain the actual genetic information coding for protein
desmin
Exons
Common amino acids in elastin
Covalent alterations
27. Each codon specifies only 1 amino acid
Protein synthesis initiation
Neurofilaments
unambiguous
Step one of RNA processing
28. Inhibit formation of the initation complex and cause misreading of mRNA
Aminoglycosides
CDKs
degenerate or redundant
What does the hydroxylation of proline and lysine require
29. 2 H bonds greater GC content greater melting point
What ties teh nucleosome together
A- T
nucleotide
Enhancers and silencer may be located_____
30. Microtubule polymerization defect resulting in lowered phagocytosis. results in recurrent pyogenic infections - partial albinism and peripheral neuropathy
Tetracyclines
Chediak Higashi syndrome
missense mutation
pyrimadines
31. Inhibits bacterials dihydrofolate reducatese down thymine
RNA processing in eukaryotes occurs
helicase
What type of collagen is most affected in Ehlers Danlos
trimethoprim
32. Inhibits thymidylate synthase down thymine
Outside the cell what processing must be done in procolalgen
Collagedn synthesis where?
5FU
Steps in splicing
33. Completed protein is released from ribosme through simple hydrolosis and dissociates
nucleotide
Common amino acids in elastin
Termination
Hydroxylation of which amino acids are attached to Glycine to form collagen
34. Cyclin depndent kinases; consituative and inactive
Nucleotide excision repair
mRNA start codons
CDKs
Clindamycin
35. Faulty collagen synthesis causing 1) hyperextensible skin 2) tendency to bleed 3) hypermobile joints
RNA processing in eukaryotes occurs
Prokaryote RNA pol
White codon is at the 3 prime end of a tRNA
Ehlers Danlos
36. Prokaryotic only. Elongates leading strand by adding deoxynucleotides to the 3prime end. Elongates laggin strand. 3 prime to 5 prime exonuclease activity
DNA pol III
intermediate filaments
desmin
Permanent cells
37. Neurons - skeletal - and cardiac muscle - RBCs
Example of permanent cells
Prokaryote RNA pol
Non homologous end joining
White codon is at the 3 prime end of a tRNA
38. Rampant - Massive - TIny rRNA is most common - then mRNA and then tRNA
Which is the most and least abundant type of RNA
Enhancers and silencer may be located_____
GFAP
microtubule
39. Change resulting in early stop codon
Methotrexate
nonsense
Axonemal dyenin
desmin
40. The 3 prime end
Which end of the tRNA is the amino acid bound to?
Post - translational modifications
silent mutation
actin and myosin
41. Inhbits RNA pol II (found in death cap mushrooms)
alpha amintin
In eukaryotes the starting amino acid is...
DNA topoisomerases
Eukaroytes
42. The N to C
tRNA aminoacylation
Euchromatin
Digoxin (cardiac glycosides)
Protein synthesis is in which direction
43. Ketone
Alternate splicing
degenerate or redundant
Guanine has a
polyadenylation does/does not require a template
44. Substituting a pyramidine for a pyrimadine
transition
desmin
degenerate or redundant
RNA processing in eukaryotes occurs
45. RER translation of collagen alpha chains (preprocollagen) usually Gly-X-Y
Glycosolation
Osteogenesis Imperfecta
chromatin structure
Collagedn synthesis where?
46. Made from IMP precursor
Paclitaxil
5FU
single stranded binding proteinds
purines
47. Odd 30S plus 50 S=70S
Prokaryotes
Deamination of cytosine makes
Collagen
Going APE
48. Trimming removal of n or c terminal propeptides from zymogens to generate mature proteinds
Post - translational modifications
nonsense
pyrimadines
Cholchicine
49. Base+ribose+phosphate linked by a phosphodiester bond
Cyclin - CDK
nucleotide
Permanent cells
helicase
50. Inhibit DNA gyrase (specific prokaryotic topoisomerase)
RNA polymerases in eukaryotes
Oubain
The only histone not on the core
Fluoroquinolones