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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Cleave terminal regions of procollagen to transform into insoluable tropocolagen
Outside the cell what processing must be done in procolalgen
Gag on pure gold
purines
Aminoacylt - tRNA synthetase
2. Stretch of DNA that alters gene expression by binding transcription factors
microtubule
Enhancer
Molecular motor protiesn
What type of collagen is most affected in Ehlers Danlos
3. Poly adenylation
Glycosolation
step two of RNA processing
AUG codes For what in prokaryotes
transition
4. Close to - far from or even within (in an intron) the gene whose expression it regulates
Enhancers and silencer may be located_____
Cyclins
Initial transcript without processing is known as
tRNA gripping and going places
5. Cilia - glagella - mitotic spindle - neurons - centrioles
microtubule
purines
Alternate splicing
Elastase is inhibited by
6. Asymmetric fluid bilayer - contains - cholesterol - phospholipids - sphingoplipids - glycolipids - and protiends
C- G bond
White codon is at the 3 prime end of a tRNA
Plasma membrane composition
Ehlers Danlos
7. Inhibits the atpase which increases intracellular sodium which increases intracellular calcium increases cardiaccontractility
Digoxin (cardiac glycosides)
Cell cycle order
tRNA activation
Elastase is inhibited by
8. Exocytose procollagen into extracellylar sace
Silencer
Excocytosis of collagen
Double Strand DNA repair
Nucleotide excision repair
9. ATP- AMP (2 phosphoanhydride bonds)
tRNA aminoacylation
Common amino acids in elastin
purines
DNA ligase
10. 1P (blocked by tetracycline)
purines
Step one of RNA processing
Loading tRNA on to ribosome energy requirement
Free ribosomes
11. Retrograde to microtubules
dyenin
Deamination of cytosine makes
Cyclins
nucleotide
12. Inhibits bacterials dihydrofolate reducatese down thymine
trimethoprim
Double Strand DNA repair
Cell cycle
capped and tail transcript is called
13. You glyucosolate hte pro - alpha chain lysine resudens and form procollagen (triple helix of alpha chains)
In eukaryotes the starting amino acid is...
Glycosolation
universal
Neurofilaments
14. Never go to Go divide rapidly with short G1 bone marrow - gut epithelium - skin - hair follicles
mRNA is syntehsized in which direction?
Fluoroquinolones
Labile
degenerate or redundant
15. RER translation of collagen alpha chains (preprocollagen) usually Gly-X-Y
mRNA is syntehsized in which direction?
Macrolides
Collagedn synthesis where?
Introns
16. Bm - kidney - ears and eyes
Type IV collagen is an important structural component of...
Aminoglycosides
Chloramphenicol
missense mutation
17. Capping on 5 prime end (7 methylguanosine) -
Step one of RNA processing
the tRNA- amino acid bond
Cell cycle order
Promoter mutation
18. H1
DNA pol III
Elastin is broken down by
The only histone not on the core
universal
19. Accurate base pairing is required only in the first 2 nucleotide positions of an mRNA so codons differing ht e3rd wobble psoition may code for the same tRNA/amino acid code
DNA ligase
tRNA
Initial transcript without processing is known as
AUG codes For what in prokaryotes
20. 2 H bonds greater GC content greater melting point
A- T
Which end of the tRNA is the amino acid bound to?
RNA processing in eukaryotes occurs
Common amino acids in elastin
21. Specific endonucleases release the oligonucleotide containing damaged bases. DNA polymerase and logase fill and resealt eh gap
Replication fork
Nucleotide excision repair
tRNA activation
Silencer
22. 1) primary transcript combines with snRNPs and other proteins to form spliceosome 2) lariat shaped intermediate is generated 3) Lariat is removed and released to precisely join 2 exons
Heterochromatin
Steps in splicing
commaless - non - overlapping
Total energy expenditure requirement for translocation
23. Anti breast cancer - acts on mts
Paclitaxil
Going APE
Initial transcript without processing is known as
desmin
24. Genetic bone disorder (brittle bone disease) type 1 colalgen - fractures (during birth) 2) Blue sclerae 3) hearing loss 4) dental imperfections 1:10000 may be confused with child abuse
Prokaryote RNA pol
Vincristine/Vinblastine
Osteogenesis Imperfecta
Elastin is broken down by
25. Genetic code is conserved throughout evolution
Molecular motor protiesn
White codon is at the 3 prime end of a tRNA
universal
Which end of a growing DNA strand is the target
26. Activated by GTP hydrolosis initiation factors help assembel the 40 S ribosomal subunites with the initiatior tRNA and are released whent he mRNA and the ribosomal subunit assemple with the complex
polyadenylation does/does not require a template
single stranded binding proteinds
Protein synthesis initiation
Clindamycin
27. Intervening noncoding segments of DNA
Introns
Post - translational modifications
Osteogenesis Imperfecta
Which is the most and least abundant type of RNA
28. Bind 30S subunit preventing attachment of aminoacyl - tRNA
nucleotide
nucleosid
Tetracyclines
Single Strand DNA Repair types
29. 1P blocked by chloramphenicaol and macrolide
Labile
alpha amintin
Enhancer
Translocation
30. CCA AT 3 PRIME END
Enhancer
Chloramphenicol
White codon is at the 3 prime end of a tRNA
Neurofilaments
31. Does not
polyadenylation does/does not require a template
Enhancers and silencer may be located_____
Step one of RNA processing
Smooth ER
32. Microvilli - muscle contraction - cytokinesis - adhering juntions
actin and myosin
Labile
Proteosomal degradation
Elastin is broken down by
33. Faulty collagen synthesis causing 1) hyperextensible skin 2) tendency to bleed 3) hypermobile joints
Cyclins
Permanent cells
Rough ER
Ehlers Danlos
34. G1 - S - G2 - Mitosis
Nucleotide excision repair
Step one of RNA processing
Cell cycle order
C- G bond
35. Odd 30S plus 50 S=70S
Cell cycle order
Prokaryotes
Base excision repair
Non homologous end joining
36. Anit helminth - act on microtubules
DNA pol I
Euchromatin
Elastin is broken down by
Mebendazole/thiabendazole
37. Codes for formyl methionine (f - Met)
Base excision repair
Pyrimidines
AUG codes For what in prokaryotes
Going APE
38. Alpha 1 antitrypisn
Elastase is inhibited by
nucleosid
desmin
Single Strand DNA Repair types
39. Site of secretory protiens (mucus secreting goblet cells and antibody secreting cells)
Nucleotide excision repair
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
Rough ER
Outside the cell what processing must be done in procolalgen
40. Proline - glycine
Common amino acids in elastin
Guanine has a
Introns
What type of collagen is most affected in Ehlers Danlos
41. Change resulting in early stop codon
universal
trimethoprim
Protein synthesis initiation
nonsense
42. Must be both activated and inactivated for cell cycle to progress
Cyclin - CDK
hydroxyurea
Translocation
capped and tail transcript is called
43. Inhibits thymidylate synthase down thymine
tRNA activation
nonsense
White codon is at the 3 prime end of a tRNA
5FU
44. Neuroglia
DNA ligase
GFAP
helicase
Ehlers Danlos
45. Be So Totatally Cool Read Books (bOne - CarTWOlage - Threeticular - Type IV under the floor)
Type IV collagen is an important structural component of...
Elongation
Collagen
Protein synthesis is in which direction
46. Less condensed - transciptionally active=eu truly transcobed
Euchromatin
Associations of Ehlers Danlos
Labile
Paclitaxil
47. Regulatory proteins that control cell cycle events; phase specific; activated CDKs
Cyclins
Functional organization of the gene
What type of collagen is most affected in Ehlers Danlos
Single Strand DNA Repair types
48. MRNA
Steps in splicing
capped and tail transcript is called
helicase
Vincristine/Vinblastine
49. The 3 prime hydroxyl of the nascent chain is the target
Free ribosomes
Which end of a growing DNA strand is the target
microtubule
Neurofilaments
50. Mutation in nucleotide excision repair Dry skin with melanoma and other cancers
DNA pol I
Xeroderma pigmentosum
cytokeratin
Total energy expenditure requirement for translocation