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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Same aa often base change in 3rd position of codon
silent mutation
Deamination of cytosine makes
Neurofilaments
Which end of the tRNA is the amino acid bound to?
2. AD and AR- associated iwth joint dislocation - berry aneurysms - organ rupture
Associations of Ehlers Danlos
Loading tRNA on to ribosome energy requirement
Tetracyclines
Thymine has a
3. ATP- AMP (2 phosphoanhydride bonds)
6MP
tRNA aminoacylation
RNA polymerases in eukaryotes
Prokaryotes
4. Bind 30S subunit preventing attachment of aminoacyl - tRNA
Which end of a growing DNA strand is the target
Tetracyclines
transversion
Enhancers and silencer may be located_____
5. Contain the actual genetic information coding for protein
Nucleotide excision repair
Cyclins
Exons
DNA pol III
6. Even 40S 60S =80S
Glycosolation
Loading tRNA on to ribosome energy requirement
Smooth ER
Eukaroytes
7. Muscle
Enhancer
Guanine has a
desmin
nonsense
8. Splicing out of introns
Step Three of RNA processing
Steps in splicing
Aminoacylt - tRNA synthetase
Type IV collagen is an important structural component of...
9. Bind 50S blocking translocation
pyrimadines
Type IV collagen is an important structural component of...
Macrolides
Hereditary non polyposis colorectal cancer
10. Base + ribose
Protein synthesis initiation
Vincristine/Vinblastine
nucleosid
Aminoacylt - tRNA synthetase
11. ATP
frame shift
tRNA activation
Functional organization of the gene
Cell cycle order
12. Trimming removal of n or c terminal propeptides from zymogens to generate mature proteinds
Cell cycle order
DNA topoisomerases
C- G bond
Post - translational modifications
13. Must be both activated and inactivated for cell cycle to progress
Collagen
Cyclin - CDK
Going APE
Type IV collagen is an important structural component of...
14. Neuroglia
step two of RNA processing
GFAP
Which is the most and least abundant type of RNA
actin and myosin
15. Faulty collagen synthesis causing 1) hyperextensible skin 2) tendency to bleed 3) hypermobile joints
Ehlers Danlos
RNA processing in eukaryotes occurs
Where do introns and exons stay
unambiguous
16. Y shaped region along DNA template where leading and lagging strands are syntehsized
Replication fork
helicase
microtubule
DNA/RNA/Protein syntesis direction
17. The N to C
Protein synthesis is in which direction
Digoxin (cardiac glycosides)
In eukaryotes the starting amino acid is...
Steps in splicing
18. Anti cancer - act on microtubules
Aminoacylt - tRNA synthetase
Vincristine/Vinblastine
Mismatch repair
Labile
19. AUG inAUGurates protein synthesis
mRNA start codons
mRNA stop codons
single stranded binding proteinds
Collagen
20. H1
Tetracyclines
Purines
The only histone not on the core
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
21. A malfunction of mismatch repair (MUt L etc..)
Cell cycle order
Hereditary non polyposis colorectal cancer
Griseofulvin
the tRNA- amino acid bond
22. Proline - glycine
transition
Common amino acids in elastin
Sodium K ATPase
Associations of Ehlers Danlos
23. Inhibits bacterials dihydrofolate reducatese down thymine
Step one of RNA processing
Enhancers and silencer may be located_____
trimethoprim
dyenin
24. Inhibits by binding to the potassium side
Oubain
6MP
Step one of RNA processing
What type of collagen is most affected in Ehlers Danlos
25. Substituting a pyramidine for a pyrimadine
transition
DNA pol I
tRNA gripping and going places
single stranded binding proteinds
26. (A - G) 2 rings Pure As Gold
Aminoacylt - tRNA synthetase
Which end of the nucleotide has the triphosphate
Purines
transition
27. Create a nick in the helix to relieve supercoils created during replication
Permanent cells
Methotrexate
Associations of Ehlers Danlos
DNA topoisomerases
28. Made from IMP precursor
purines
nucleosid
DNA topoisomerases
Silencer
29. 1P blocked by chloramphenicaol and macrolide
Mismatch repair
Translocation
Oubain
trimethoprim
30. Cilia - glagella - mitotic spindle - neurons - centrioles
Cilia structure
Cholchicine
microtubule
Free ribosomes
31. Xlinked recessive IV collagen bm - kidney - ear and eye -- nephritis and defness ocular disturbances
Which is the most and least abundant type of RNA
Outside the cell what processing must be done in procolalgen
Alports syndrome
Protein synthesis initiation
32. Microtubule polymerization defect resulting in lowered phagocytosis. results in recurrent pyogenic infections - partial albinism and peripheral neuropathy
Chediak Higashi syndrome
Hydroxylation of which amino acids are attached to Glycine to form collagen
tRNA Structure
nucleosid
33. Inhibits dihydrofolate reductase down thymine
Step Three of RNA processing
Hydroxylation of which amino acids are attached to Glycine to form collagen
Methotrexate
Immunohistochemical stains vimentin
34. Unattached to any membrane; site of cytosolic and organeller prtoeins
Free ribosomes
chromatin structure
tRNA activation
Example of permanent cells
35. Promoter - enhancer - promoter - TATA- transcription initiation site - coding region (including exons and introns) and then the AATAAA
hydroxyurea
Functional organization of the gene
Aminoglycosides
Euchromatin
36. Cylindrical structure composed of helical array of plymerized dimers of alpha and beta tubulin - flagella - cilia - mitotic spindle - grows slowly collapses quickly
Molecular motor protiesn
microtubule
alpha amintin
polyadenylation does/does not require a template
37. Enter G1 from G0 when stimulated Hepatocytes/lymphocytes
Stable (quiescent)
RNA processing in eukaryotes occurs
Tetracyclines
In eukaryotes the starting amino acid is...
38. H1 string
Hydroxylation of which amino acids are attached to Glycine to form collagen
Pyrimidines
What ties teh nucleosome together
Elastin
39. Type III
Alports syndrome
Collagen
DNA pol III
What type of collagen is most affected in Ehlers Danlos
40. Non homologous end joining
Double Strand DNA repair
unambiguous
AUG codes For what in prokaryotes
Type IV collagen is an important structural component of...
41. Hydroxy proline and hydroxylysine
Hydroxylation of which amino acids are attached to Glycine to form collagen
Gag on pure gold
DNA pol III
universal
42. Three amino acids necessary for purine synthesis= glutamine - aspartate and glycine
White codon is at the 3 prime end of a tRNA
Stable (quiescent)
Elastin is broken down by
Gag on pure gold
43. Rampant - Massive - TIny rRNA is most common - then mRNA and then tRNA
Which is the most and least abundant type of RNA
alpha amintin
Methotrexate
Protein synthesis is in which direction
44. Nucleotide excision repair - Base Excision repair - Mismath repair
Which end of a growing DNA strand is the target
Single Strand DNA Repair types
intermediate filaments
Chediak Higashi syndrome
45. Commonly results in dramatic decrease in amount of gene transcribed
Aminoacylt - tRNA synthetase
Euchromatin
tRNA gripping and going places
Promoter mutation
46. Asymmetric fluid bilayer - contains - cholesterol - phospholipids - sphingoplipids - glycolipids - and protiends
Plasma membrane composition
Example of permanent cells
Griseofulvin
Pyrimidines
47. Alpha 1 antitrypisn
Thymine has a
DNA/RNA/Protein syntesis direction
capped and tail transcript is called
Elastase is inhibited by
48. Particular sequnece in genomre where DNA replication begins. May be single (prokaryotes) or multiple (eukaryotes)
Clindamycin
origin of replication
Rough ER
Functional organization of the gene
49. Aminoacyl - tRNA binds to A site 2) peptidyltransferase catalyzes peptide bond formation transfers growing polypeptie to amino acid in A site 3) ribosome advances 3 nucleotides toward the 3 prime end of RNA moving peptiydyl RNA to P site
Elongation
RNA polymerases in eukaryotes
Elastin is broken down by
nonsense
50. RER translation of collagen alpha chains (preprocollagen) usually Gly-X-Y
Deamination of cytosine makes
Higher the cholesterol or long saturated fatty acid content
5FU
Collagedn synthesis where?