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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Poly adenylation
Which end of the nucleotide has the triphosphate
step two of RNA processing
Covalent alterations
Proteosomal degradation
2. Prokaryotic only. Degrades RNA primer and fills in the gap with DNA (5 prime to 3 prime exonuclease)
RNA processing in eukaryotes occurs
DNA pol I
nucleotide
A- T
3. Inhibit DNA gyrase (specific prokaryotic topoisomerase)
Silencer
Collagen
Digoxin (cardiac glycosides)
Fluoroquinolones
4. Immotile cilia due to a dyenin arm defect. Results in male nad female inferticility (sperm immotile) - bronchiectasis - and recurrent sinusisits - associated with situs inversus
Loading tRNA on to ribosome energy requirement
purines
Enhancers and silencer may be located_____
Kartageners syndrome
5. Must be both activated and inactivated for cell cycle to progress
RNA polymerases in eukaryotes
Alternate splicing
Cyclin - CDK
alpha amintin
6. Prophas - metaphase - anaphase telophase
capped and tail transcript is called
Oubain
Smooth ER
Order of mitosis
7. 75-90 nucleotides - 2ary structure cloverleaf form anticodon end is opposite 3 prime aminoacyl end
tRNA Structure
Mebendazole/thiabendazole
nonsense
Methotrexate
8. AUG inAUGurates protein synthesis
mRNA start codons
Cell cycle
tRNA aminoacylation
dyenin
9. Inhibits bacterials dihydrofolate reducatese down thymine
trimethoprim
DNA topoisomerases
Post - translational modifications
Which end of the nucleotide has the triphosphate
10. Methionine - which may be removed before translation is completed
Cilia structure
Molecular motor protiesn
In eukaryotes the starting amino acid is...
Functional organization of the gene
11. Promoter - enhancer - promoter - TATA- transcription initiation site - coding region (including exons and introns) and then the AATAAA
Xeroderma pigmentosum
Elastin is broken down by
Functional organization of the gene
Sodium K ATPase
12. Responsible for the accuracy of amino acid selection
Aminoglycosides
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
Post - translational modifications
CDKs
13. Regulatory proteins that control cell cycle events; phase specific; activated CDKs
tRNA
RNA processing in eukaryotes occurs
Aminoacylt - tRNA synthetase
Cyclins
14. Change resulting in early stop codon
tRNA aminoacylation
Collagedn synthesis where?
nonsense
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
15. Methyl THYmine has a meTHYl
microtubule
Thymine has a
Hereditary non polyposis colorectal cancer
Initial transcript without processing is known as
16. Anti breast cancer - acts on mts
Alports syndrome
Cyclin - CDK
Paclitaxil
DNA topoisomerases
17. Read froma fixed starting point as a continous sequenecs of bases
Thymine has a
Alternate splicing
commaless - non - overlapping
Purines
18. RNA polymerase I makes rRNA - RNA pol II makes mRNA - RNA pol III makes tRNA
unambiguous
trimethoprim
Introns
RNA polymerases in eukaryotes
19. Phosphorylation - glycosloation - hyderoxylation
Covalent alterations
polyadenylation does/does not require a template
Labile
Permanent cells
20. You glyucosolate hte pro - alpha chain lysine resudens and form procollagen (triple helix of alpha chains)
Primase
Glycosolation
White codon is at the 3 prime end of a tRNA
Euchromatin
21. Retrograde to microtubules
Labile
dyenin
What does the hydroxylation of proline and lysine require
microtubule
22. Hn RNA
RNA polymerases in eukaryotes
Initial transcript without processing is known as
Smooth ER
Guanine has a
23. Attachment of ubiquitin to defective proteinds to tag them for breakdown
Proteosomal degradation
Which is the most and least abundant type of RNA
Elastin is broken down by
Aminoglycosides
24. Stretch of DNA that alters gene expression by binding transcription factors
Which end of the tRNA is the amino acid bound to?
Enhancer
6MP
Post - translational modifications
25. Substituting a purine for a pyrimdine or vice versa
transversion
Elastin is broken down by
DNA ligase
5FU
26. Site where negative regulators bind
Silencer
DNA ligase
Hydroxylation of which amino acids are attached to Glycine to form collagen
Single Strand DNA Repair types
27. 9+2 arrangement of microtubules -
Cilia structure
desmin
Exons
Functional organization of the gene
28. Has enough energy to created the peptide bond
tRNA
Paclitaxil
the tRNA- amino acid bond
universal
29. Odd 30S plus 50 S=70S
Single Strand DNA Repair types
Order of mitosis
Prokaryotes
Tumor Suppressors
30. Nucleotide excision repair - Base Excision repair - Mismath repair
Promoter mutation
Tumor Suppressors
Single Strand DNA Repair types
nucleotide
31. Bm - kidney - ears and eyes
degenerate or redundant
Type IV collagen is an important structural component of...
Cilia structure
frame shift
32. Neuroglia
GFAP
What does the hydroxylation of proline and lysine require
Excocytosis of collagen
Fluoroquinolones
33. Codes for formyl methionine (f - Met)
AUG codes For what in prokaryotes
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
Total energy expenditure requirement for translocation
Elastase is inhibited by
34. In the nucleus after transcitpion and only processed RNA is transporte out of the nucleus
promoter
Chediak Higashi syndrome
Pyrimidines
RNA processing in eukaryotes occurs
35. Three amino acids necessary for purine synthesis= glutamine - aspartate and glycine
AUG codes For what in prokaryotes
silent mutation
Gag on pure gold
Exons
36. Commonly results in dramatic decrease in amount of gene transcribed
microtubule
Cell cycle order
Promoter mutation
Order of mitosis
37. Xlinked recessive IV collagen bm - kidney - ear and eye -- nephritis and defness ocular disturbances
Prokaryote RNA pol
Xeroderma pigmentosum
Order of mitosis
Alports syndrome
38. Prokaryotic only. Elongates leading strand by adding deoxynucleotides to the 3prime end. Elongates laggin strand. 3 prime to 5 prime exonuclease activity
A- T
DNA pol III
White codon is at the 3 prime end of a tRNA
Introns
39. Inhibits dihydrofolate reductase down thymine
Aminoacylt - tRNA synthetase
Protein synthesis initiation
Methotrexate
trimethoprim
40. Contain the actual genetic information coding for protein
Exons
Vincristine/Vinblastine
DNA pol I
Digoxin (cardiac glycosides)
41. Intervening noncoding segments of DNA
tRNA Structure
Molecular motor protiesn
What type of collagen is most affected in Ehlers Danlos
Introns
42. DNA And RNA synthesized in the 5-3 direction
DNA/RNA/Protein syntesis direction
Rough ER
Pyrimidines
Which is the most and least abundant type of RNA
43. Y shaped region along DNA template where leading and lagging strands are syntehsized
Prokaryotes
intermediate filaments
Replication fork
universal
44. Tansport cellular cargo toward opposite ends of microtubule tracks
Methotrexate
Chediak Higashi syndrome
Functional organization of the gene
Molecular motor protiesn
45. Asymmetric fluid bilayer - contains - cholesterol - phospholipids - sphingoplipids - glycolipids - and protiends
Where do introns and exons stay
silent mutation
Griseofulvin
Plasma membrane composition
46. 1P blocked by chloramphenicaol and macrolide
Chloramphenicol
RNA processing in eukaryotes occurs
Translocation
Cyclins
47. Base+ribose+phosphate linked by a phosphodiester bond
Neurofilaments
nonsense
nucleotide
CDKs
48. Ketone
Osteogenesis Imperfecta
Guanine has a
RNA processing in eukaryotes occurs
Hereditary non polyposis colorectal cancer
49. Ribonucleotide reductase
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
DNA pol III
mRNA is syntehsized in which direction?
Chloramphenicol
50. Less condensed - transciptionally active=eu truly transcobed
Euchromatin
Which end of a growing DNA strand is the target
universal
C- G bond