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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Prevents stranges from reannealing
Immunohistochemical stains vimentin
Oubain
single stranded binding proteinds
Which end of the tRNA is the amino acid bound to?
2. Elastase
Aminoglycosides
Protein synthesis initiation
Elastin is broken down by
cytokeratin
3. Different exons can be combined to make nique protiens in different times
Alternate splicing
Aminoglycosides
Common amino acids in elastin
Single Strand DNA Repair types
4. Antigout - acts on mts
Cholchicine
Macrolides
nonsense
Cyclins
5. Change resulting in misreading of all nucleotides downstream - usually resulting in a truncated non functional protien
Guanine has a
desmin
frame shift
Axonemal dyenin
6. ATP ase that links peripheral 9 doublets and causes bending of cilium by differential sliding of doublets
A- T
Axonemal dyenin
universal
Aminoglycosides
7. Prokaryotic only. Degrades RNA primer and fills in the gap with DNA (5 prime to 3 prime exonuclease)
Pyrimidines
Where do introns and exons stay
Step one of RNA processing
DNA pol I
8. Bind 30S subunit preventing attachment of aminoacyl - tRNA
Higher the cholesterol or long saturated fatty acid content
Tetracyclines
Mismatch repair
Single Strand DNA Repair types
9. Anti cancer - act on microtubules
Prokaryotes
Outside the cell what processing must be done in procolalgen
Silencer
Vincristine/Vinblastine
10. CCA AT 3 PRIME END
Order of mitosis
tRNA
Sodium K ATPase
White codon is at the 3 prime end of a tRNA
11. Read froma fixed starting point as a continous sequenecs of bases
Excocytosis of collagen
RNA processing in eukaryotes occurs
commaless - non - overlapping
Termination
12. (A - G) 2 rings Pure As Gold
Covalent alterations
Purines
Hereditary non polyposis colorectal cancer
Digoxin (cardiac glycosides)
13. Responsible for the accuracy of amino acid selection
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
Euchromatin
intermediate filaments
tRNA Structure
14. A site - incoming aminoacyl tRNA - Psite accomodates growing Peptide - E site holds EmplytRNA as it exits
Going APE
Outside the cell what processing must be done in procolalgen
C- G bond
DNA/RNA/Protein syntesis direction
15. Three amino acids necessary for purine synthesis= glutamine - aspartate and glycine
step two of RNA processing
White codon is at the 3 prime end of a tRNA
Gag on pure gold
transition
16. Accurate base pairing is required only in the first 2 nucleotide positions of an mRNA so codons differing ht e3rd wobble psoition may code for the same tRNA/amino acid code
commaless - non - overlapping
dyenin
trimethoprim
tRNA
17. In the nucleus after transcitpion and only processed RNA is transporte out of the nucleus
Deamination of cytosine makes
RNA processing in eukaryotes occurs
Purines
Cell cycle order
18. Has enough energy to created the peptide bond
the tRNA- amino acid bond
AUG codes For what in prokaryotes
Osteogenesis Imperfecta
Single Strand DNA Repair types
19. 3 H bonds
Molecular motor protiesn
Covalent alterations
Primase
C- G bond
20. Inhibits dihydrofolate reductase down thymine
Methotrexate
polyadenylation does/does not require a template
Which is the most and least abundant type of RNA
What ties teh nucleosome together
21. RNA polymerase I makes rRNA - RNA pol II makes mRNA - RNA pol III makes tRNA
Type IV collagen is an important structural component of...
single stranded binding proteinds
RNA polymerases in eukaryotes
nucleosid
22. Retrograde to microtubules
Replication fork
Outside the cell what processing must be done in procolalgen
dyenin
Fluoroquinolones
23. Genetic bone disorder (brittle bone disease) type 1 colalgen - fractures (during birth) 2) Blue sclerae 3) hearing loss 4) dental imperfections 1:10000 may be confused with child abuse
Outside the cell what processing must be done in procolalgen
Osteogenesis Imperfecta
methionine is only encoded by
Proteosomal degradation
24. Type III
tRNA
What type of collagen is most affected in Ehlers Danlos
Mebendazole/thiabendazole
DNA pol I
25. Codes for formyl methionine (f - Met)
AUG codes For what in prokaryotes
Nucleotide excision repair
histone octamer names
nucleosid
26. Made from IMP precursor
purines
Single Strand DNA Repair types
Associations of Ehlers Danlos
DNA/RNA/Protein syntesis direction
27. Aminoacyl - tRNA binds to A site 2) peptidyltransferase catalyzes peptide bond formation transfers growing polypeptie to amino acid in A site 3) ribosome advances 3 nucleotides toward the 3 prime end of RNA moving peptiydyl RNA to P site
Elongation
the tRNA- amino acid bond
Hereditary non polyposis colorectal cancer
origin of replication
28. The 3 prime hydroxyl of the nascent chain is the target
Double Strand DNA repair
kinesin
Associations of Ehlers Danlos
Which end of a growing DNA strand is the target
29. Inhibits the atpase which increases intracellular sodium which increases intracellular calcium increases cardiaccontractility
polyadenylation does/does not require a template
Digoxin (cardiac glycosides)
Total energy expenditure requirement for translocation
Gag on pure gold
30. Scrutinizes aa before and after it binds to tRNA. If incorrect bond is hydrolyzed.
Aminoacylt - tRNA synthetase
hydroxyurea
transversion
degenerate or redundant
31. Asymmetric fluid bilayer - contains - cholesterol - phospholipids - sphingoplipids - glycolipids - and protiends
Sodium K ATPase
Plasma membrane composition
Prokaryotes
Stable (quiescent)
32. You glyucosolate hte pro - alpha chain lysine resudens and form procollagen (triple helix of alpha chains)
Excocytosis of collagen
Glycosolation
C- G bond
Prokaryote RNA pol
33. DNA And RNA synthesized in the 5-3 direction
Which end of a growing DNA strand is the target
Hydroxylation of which amino acids are attached to Glycine to form collagen
DNA/RNA/Protein syntesis direction
microtubule
34. Trimming removal of n or c terminal propeptides from zymogens to generate mature proteinds
Which end of a growing DNA strand is the target
Collagedn synthesis where?
Covalent alterations
Post - translational modifications
35. Each codon specifies only 1 amino acid
Double Strand DNA repair
unambiguous
transition
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
36. 4 high enrgy bonds
Total energy expenditure requirement for translocation
dyenin
Rough ER
single stranded binding proteinds
37. Same aa often base change in 3rd position of codon
Tropocollagen cross links between_____ to form____
silent mutation
Loading tRNA on to ribosome energy requirement
alpha amintin
38. Create a nick in the helix to relieve supercoils created during replication
purines
trimethoprim
DNA topoisomerases
Elastase is inhibited by
39. Cylindrical structure composed of helical array of plymerized dimers of alpha and beta tubulin - flagella - cilia - mitotic spindle - grows slowly collapses quickly
Mismatch repair
microtubule
Glycosolation
actin and myosin
40. Site of dteroid synthesis and detoxification of druigs and poisons (liver hepatocytes and steroid horomore adrenal cortex)
Vincristine/Vinblastine
Aminoglycosides
Tumor Suppressors
Smooth ER
41. Neurons
Associations of Ehlers Danlos
Order of mitosis
Digoxin (cardiac glycosides)
Neurofilaments
42. Non homologous end joining
Double Strand DNA repair
tRNA aminoacylation
Guanine has a
step two of RNA processing
43. Neurons - skeletal - and cardiac muscle - RBCs
Example of permanent cells
Loading tRNA on to ribosome energy requirement
Aminoglycosides
Proteosomal degradation
44. AD and AR- associated iwth joint dislocation - berry aneurysms - organ rupture
Associations of Ehlers Danlos
Excocytosis of collagen
Macrolides
Protein synthesis initiation
45. Changed aaconservative - new aa is similar in chemical structure
Enhancers and silencer may be located_____
chromatin structure
missense mutation
RNA processing in eukaryotes occurs
46. Cleave terminal regions of procollagen to transform into insoluable tropocolagen
Neurofilaments
Termination
What type of collagen is most affected in Ehlers Danlos
Outside the cell what processing must be done in procolalgen
47. Ketone
Guanine has a
trimethoprim
missense mutation
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
48. Antifungal - act on microtubules
the tRNA- amino acid bond
Proofreading function in eukaryotic RNA
Griseofulvin
Proteosomal degradation
49. 1P blocked by chloramphenicaol and macrolide
origin of replication
DNA/RNA/Protein syntesis direction
Enhancer
Translocation
50. Site of secretory protiens (mucus secreting goblet cells and antibody secreting cells)
Rough ER
Initial transcript without processing is known as
Total energy expenditure requirement for translocation
alpha amintin