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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Scrutinizes aa before and after it binds to tRNA. If incorrect bond is hydrolyzed.
Fluoroquinolones
Aminoacylt - tRNA synthetase
tRNA Structure
Exons
2. Retrograde to microtubules
Which end of the nucleotide has the triphosphate
Outside the cell what processing must be done in procolalgen
The only histone not on the core
dyenin
3. 1 RNA polymerase (multisubunite complex) makes all 3 kinds of RNA
single stranded binding proteinds
Prokaryote RNA pol
Protein synthesis initiation
Tropocollagen cross links between_____ to form____
4. Genetic bone disorder (brittle bone disease) type 1 colalgen - fractures (during birth) 2) Blue sclerae 3) hearing loss 4) dental imperfections 1:10000 may be confused with child abuse
Osteogenesis Imperfecta
Functional organization of the gene
Step one of RNA processing
Pyrimidines
5. Asymmetric fluid bilayer - contains - cholesterol - phospholipids - sphingoplipids - glycolipids - and protiends
Free ribosomes
Order of mitosis
transition
Plasma membrane composition
6. Commonly results in dramatic decrease in amount of gene transcribed
Promoter mutation
Cell cycle
Where do introns and exons stay
The only histone not on the core
7. Remain in G0 regenerate from stem cells
Nucleotide excision repair
Order of mitosis
Permanent cells
Clindamycin
8. Has enough energy to created the peptide bond
DNA/RNA/Protein syntesis direction
the tRNA- amino acid bond
Which is the most and least abundant type of RNA
Rough ER
9. Non homologous end joining
commaless - non - overlapping
Double Strand DNA repair
Common amino acids in elastin
Which end of a growing DNA strand is the target
10. Cyclin depndent kinases; consituative and inactive
Vincristine/Vinblastine
Enhancer
CDKs
Promoter mutation
11. Hydroxy proline and hydroxylysine
unambiguous
Hydroxylation of which amino acids are attached to Glycine to form collagen
nonsense
Loading tRNA on to ribosome energy requirement
12. Seals
Going APE
Translocation
promoter
DNA ligase
13. Odd 30S plus 50 S=70S
Prokaryotes
Tetracyclines
nucleosid
tRNA aminoacylation
14. Cilia - glagella - mitotic spindle - neurons - centrioles
degenerate or redundant
DNA pol III
microtubule
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
15. Methionine - which may be removed before translation is completed
DNA/RNA/Protein syntesis direction
Sodium K ATPase
Common amino acids in elastin
In eukaryotes the starting amino acid is...
16. P53 and RB normally inhibit g1 to S progression
6MP
Tumor Suppressors
C- G bond
actin and myosin
17. Same aa often base change in 3rd position of codon
tRNA Structure
silent mutation
Hydroxylation of which amino acids are attached to Glycine to form collagen
transversion
18. Substituting a pyramidine for a pyrimadine
What type of collagen is most affected in Ehlers Danlos
tRNA Structure
C- G bond
transition
19. Connective tissue
Rough ER
Immunohistochemical stains vimentin
Enhancers and silencer may be located_____
Step Three of RNA processing
20. Activated by GTP hydrolosis initiation factors help assembel the 40 S ribosomal subunites with the initiatior tRNA and are released whent he mRNA and the ribosomal subunit assemple with the complex
polyadenylation does/does not require a template
Protein synthesis initiation
Exons
Which is the most and least abundant type of RNA
21. Inhibits bacterials dihydrofolate reducatese down thymine
trimethoprim
Where do introns and exons stay
What type of collagen is most affected in Ehlers Danlos
the tRNA- amino acid bond
22. Antigout - acts on mts
Free ribosomes
Cilia structure
Cholchicine
nucleotide
23. HS1 - HSB - H2 - H4
Aminoacylt - tRNA synthetase
histone octamer names
Total energy expenditure requirement for translocation
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
24. Less condensed - transciptionally active=eu truly transcobed
Euchromatin
Example of permanent cells
mRNA start codons
What ties teh nucleosome together
25. Regulatory proteins that control cell cycle events; phase specific; activated CDKs
Total energy expenditure requirement for translocation
Chloramphenicol
Proteosomal degradation
Cyclins
26. Unmethylated - newly synthesized string is recognized - mismatched nucleotides are removed and the gap is filled and resealed
helicase
Mismatch repair
GFAP
Proteosomal degradation
27. Inhibits the atpase which increases intracellular sodium which increases intracellular calcium increases cardiaccontractility
Guanine has a
Termination
Digoxin (cardiac glycosides)
Which end of the tRNA is the amino acid bound to?
28. Faulty collagen synthesis causing 1) hyperextensible skin 2) tendency to bleed 3) hypermobile joints
Proteosomal degradation
Ehlers Danlos
Guanine has a
universal
29. Substituting a purine for a pyrimdine or vice versa
Thymine has a
A- T
transversion
Tumor Suppressors
30. Does not
polyadenylation does/does not require a template
Prokaryotes
C- G bond
histone octamer names
31. Unwinds DNA template at replication fork
helicase
Fluoroquinolones
Steps in splicing
Paclitaxil
32. Blocks denovo purine synthesis
6MP
Initial transcript without processing is known as
Which end of the tRNA is the amino acid bound to?
Thymine has a
33. RER translation of collagen alpha chains (preprocollagen) usually Gly-X-Y
Elastin
Stable (quiescent)
Initial transcript without processing is known as
Collagedn synthesis where?
34. ATP
RNA processing in eukaryotes occurs
degenerate or redundant
What does the hydroxylation of proline and lysine require
tRNA activation
35. RNA polymerase I makes rRNA - RNA pol II makes mRNA - RNA pol III makes tRNA
RNA processing in eukaryotes occurs
RNA polymerases in eukaryotes
What does the hydroxylation of proline and lysine require
Cilia structure
36. Type III
What type of collagen is most affected in Ehlers Danlos
Initial transcript without processing is known as
kinesin
Mebendazole/thiabendazole
37. Xlinked recessive IV collagen bm - kidney - ear and eye -- nephritis and defness ocular disturbances
Enhancer
Protein synthesis is in which direction
Alports syndrome
Paclitaxil
38. Bind 30S subunit preventing attachment of aminoacyl - tRNA
Tetracyclines
In eukaryotes the starting amino acid is...
Order of mitosis
Hydroxylation of which amino acids are attached to Glycine to form collagen
39. Inhibits thymidylate synthase down thymine
Neurofilaments
nonsense
Aminoacylt - tRNA synthetase
5FU
40. Bind 50S blocking translocation
Fluoroquinolones
Macrolides
Euchromatin
capped and tail transcript is called
41. Anterograde to microtubule
Elastase is inhibited by
hydroxyurea
kinesin
Collagen
42. Microvilli - muscle contraction - cytokinesis - adhering juntions
polyadenylation does/does not require a template
actin and myosin
trimethoprim
Loading tRNA on to ribosome energy requirement
43. Inhibits 50S peptidyl transferase
The only histone not on the core
Aminoglycosides
5FU
Chloramphenicol
44. Different exons can be combined to make nique protiens in different times
Alternate splicing
Labile
Step one of RNA processing
Base excision repair
45. 75-90 nucleotides - 2ary structure cloverleaf form anticodon end is opposite 3 prime aminoacyl end
Macrolides
single stranded binding proteinds
tRNA Structure
RNA processing in eukaryotes occurs
46. Three amino acids necessary for purine synthesis= glutamine - aspartate and glycine
Xeroderma pigmentosum
Gag on pure gold
Total energy expenditure requirement for translocation
Vincristine/Vinblastine
47. Rampant - Massive - TIny rRNA is most common - then mRNA and then tRNA
Thymine has a
Molecular motor protiesn
RNA processing in eukaryotes occurs
Which is the most and least abundant type of RNA
48. Promoter - enhancer - promoter - TATA- transcription initiation site - coding region (including exons and introns) and then the AATAAA
mRNA stop codons
Functional organization of the gene
Molecular motor protiesn
Type IV collagen is an important structural component of...
49. Intervening noncoding segments of DNA
C- G bond
Deamination of cytosine makes
Excocytosis of collagen
Introns
50. Microtubule polymerization defect resulting in lowered phagocytosis. results in recurrent pyogenic infections - partial albinism and peripheral neuropathy
Nucleotide excision repair
Chediak Higashi syndrome
Chloramphenicol
Alternate splicing