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First Aid: Biochemistry Molecular

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. No proofreading function but can initiate chains. RNA poymerase II opens DNA at promoter site






2. Condensed - transciptionally inactive HC- Highly condensed






3. CCA AT 3 PRIME END






4. Unmethylated - newly synthesized string is recognized - mismatched nucleotides are removed and the gap is filled and resealed






5. Poly adenylation






6. Makes an RNA primer on which DNA polymerase II can initiate replication






7. Negatively charged DNA loops twice around histone octamers create a nucloesome bead.






8. AUG inAUGurates protein synthesis






9. H1






10. Cilia - glagella - mitotic spindle - neurons - centrioles






11. Anit helminth - act on microtubules






12. Capping on 5 prime end (7 methylguanosine) -






13. Anti breast cancer - acts on mts






14. Inhibits dihydrofolate reductase down thymine






15. 5 prime to 3 prime






16. Cleave terminal regions of procollagen to transform into insoluable tropocolagen






17. The 3 prime hydroxyl of the nascent chain is the target






18. Inhibits 50S peptidyl transferase






19. Attachment of ubiquitin to defective proteinds to tag them for breakdown






20. A site - incoming aminoacyl tRNA - Psite accomodates growing Peptide - E site holds EmplytRNA as it exits






21. Made from orogate precuror with PRPP added later






22. Cylindrical structure composed of helical array of plymerized dimers of alpha and beta tubulin - flagella - cilia - mitotic spindle - grows slowly collapses quickly






23. Ketone






24. The N to C






25. Vimentin - desmin - cytockeratin - glial fibrillary acid proteins - neurofilaments






26. Hydroxy proline and hydroxylysine






27. Checkpoints control transition between phases of cell cycle. regulated by cyclins - CDKs and tumor suppressors. Mitosis (shortest phse)






28. Prokaryotic only. Elongates leading strand by adding deoxynucleotides to the 3prime end. Elongates laggin strand. 3 prime to 5 prime exonuclease activity






29. Each codon specifies only 1 amino acid






30. Create a nick in the helix to relieve supercoils created during replication






31. MRNA






32. Contain the actual genetic information coding for protein






33. Site of dteroid synthesis and detoxification of druigs and poisons (liver hepatocytes and steroid horomore adrenal cortex)






34. Does not






35. 9+2 arrangement of microtubules -






36. Prevents stranges from reannealing






37. ATP- AMP (2 phosphoanhydride bonds)






38. Even 40S 60S =80S






39. Aminoacyl - tRNA binds to A site 2) peptidyltransferase catalyzes peptide bond formation transfers growing polypeptie to amino acid in A site 3) ribosome advances 3 nucleotides toward the 3 prime end of RNA moving peptiydyl RNA to P site






40. Methyl THYmine has a meTHYl






41. The 3 prime end






42. 1 RNA polymerase (multisubunite complex) makes all 3 kinds of RNA






43. Scrutinizes aa before and after it binds to tRNA. If incorrect bond is hydrolyzed.






44. Particular sequnece in genomre where DNA replication begins. May be single (prokaryotes) or multiple (eukaryotes)






45. 75-90 nucleotides - 2ary structure cloverleaf form anticodon end is opposite 3 prime aminoacyl end






46. Read froma fixed starting point as a continous sequenecs of bases






47. Never go to Go divide rapidly with short G1 bone marrow - gut epithelium - skin - hair follicles






48. Tansport cellular cargo toward opposite ends of microtubule tracks






49. Bind 30S subunit preventing attachment of aminoacyl - tRNA






50. Blocks denovo purine synthesis