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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Specific endonucleases release the oligonucleotide containing damaged bases. DNA polymerase and logase fill and resealt eh gap
Cyclins
Axonemal dyenin
Nucleotide excision repair
Cell cycle
2. Ketone
the tRNA- amino acid bond
Guanine has a
DNA/RNA/Protein syntesis direction
cytokeratin
3. Substituting a pyramidine for a pyrimadine
transition
Cell cycle
Nucleotide excision repair
polyadenylation does/does not require a template
4. Xlinked recessive IV collagen bm - kidney - ear and eye -- nephritis and defness ocular disturbances
Permanent cells
Chediak Higashi syndrome
Alports syndrome
step two of RNA processing
5. Capping on 5 prime end (7 methylguanosine) -
Step one of RNA processing
Collagedn synthesis where?
Digoxin (cardiac glycosides)
Deamination of cytosine makes
6. Unmethylated - newly synthesized string is recognized - mismatched nucleotides are removed and the gap is filled and resealed
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
Labile
Mismatch repair
Oubain
7. Neurons - skeletal - and cardiac muscle - RBCs
Oubain
Replication fork
tRNA gripping and going places
Example of permanent cells
8. HS1 - HSB - H2 - H4
Which end of the tRNA is the amino acid bound to?
Prokaryote RNA pol
histone octamer names
silent mutation
9. Microtubule polymerization defect resulting in lowered phagocytosis. results in recurrent pyogenic infections - partial albinism and peripheral neuropathy
Elongation
tRNA activation
Chediak Higashi syndrome
histone octamer names
10. Inhibits thymidylate synthase down thymine
5FU
mRNA stop codons
Base excision repair
Sodium K ATPase
11. Poly adenylation
Axonemal dyenin
Stable (quiescent)
Tumor Suppressors
step two of RNA processing
12. Commonly results in dramatic decrease in amount of gene transcribed
Promoter mutation
hydroxyurea
DNA topoisomerases
Proofreading function in eukaryotic RNA
13. Be So Totatally Cool Read Books (bOne - CarTWOlage - Threeticular - Type IV under the floor)
Cyclin - CDK
Collagen
Tetracyclines
Alports syndrome
14. 4 high enrgy bonds
Example of permanent cells
Total energy expenditure requirement for translocation
White codon is at the 3 prime end of a tRNA
DNA pol III
15. H1 string
What ties teh nucleosome together
Example of permanent cells
tRNA aminoacylation
Free ribosomes
16. P53 and RB normally inhibit g1 to S progression
Cell cycle order
In eukaryotes the starting amino acid is...
Common amino acids in elastin
Tumor Suppressors
17. AUG inAUGurates protein synthesis
cytokeratin
mRNA start codons
White codon is at the 3 prime end of a tRNA
Elongation
18. Phosphorylation - glycosloation - hyderoxylation
nonsense
Covalent alterations
trimethoprim
Purines
19. Brings together 2 ends of DNA fragments no requirement for homology
Non homologous end joining
Chediak Higashi syndrome
nucleotide
universal
20. Remain in G0 regenerate from stem cells
Permanent cells
Functional organization of the gene
White codon is at the 3 prime end of a tRNA
mRNA stop codons
21. Has enough energy to created the peptide bond
What does the hydroxylation of proline and lysine require
transversion
intermediate filaments
the tRNA- amino acid bond
22. 9+2 arrangement of microtubules -
nucleotide
chromatin structure
Cilia structure
desmin
23. Different exons can be combined to make nique protiens in different times
Cilia structure
Alternate splicing
Promoter mutation
Type IV collagen is an important structural component of...
24. Microvilli - muscle contraction - cytokinesis - adhering juntions
Cilia structure
Glycosolation
nucleosid
actin and myosin
25. 1P (blocked by tetracycline)
tRNA aminoacylation
Loading tRNA on to ribosome energy requirement
nucleotide
Introns
26. Vimentin - desmin - cytockeratin - glial fibrillary acid proteins - neurofilaments
intermediate filaments
Glycosolation
Cyclin - CDK
Replication fork
27. 75-90 nucleotides - 2ary structure cloverleaf form anticodon end is opposite 3 prime aminoacyl end
Initial transcript without processing is known as
Fluoroquinolones
A- T
tRNA Structure
28. Anti breast cancer - acts on mts
Clindamycin
Paclitaxil
Free ribosomes
the tRNA- amino acid bond
29. Odd 30S plus 50 S=70S
Prokaryote RNA pol
DNA ligase
Prokaryotes
Thymine has a
30. Bind 50S blocking translocation
Fluoroquinolones
Example of permanent cells
tRNA Structure
Macrolides
31. Rampant - Massive - TIny rRNA is most common - then mRNA and then tRNA
Stable (quiescent)
Tropocollagen cross links between_____ to form____
degenerate or redundant
Which is the most and least abundant type of RNA
32. UGA - UAG - UAA
Kartageners syndrome
mRNA stop codons
Termination
Eukaroytes
33. Ribonucleotide reductase
What type of collagen is most affected in Ehlers Danlos
Steps in splicing
Protein synthesis initiation
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
34. Splicing out of introns
Step Three of RNA processing
degenerate or redundant
cytokeratin
mRNA is syntehsized in which direction?
35. Neurons
Sodium K ATPase
Neurofilaments
Mismatch repair
Which is the most and least abundant type of RNA
36. Muscle
Rough ER
Molecular motor protiesn
Tumor Suppressors
desmin
37. MRNA
Enhancer
kinesin
capped and tail transcript is called
hydroxyurea
38. Trimming removal of n or c terminal propeptides from zymogens to generate mature proteinds
Base excision repair
Post - translational modifications
tRNA aminoacylation
Excocytosis of collagen
39. Inhibits dihydrofolate reductase down thymine
unambiguous
Neurofilaments
Methotrexate
Elongation
40. Antifungal - act on microtubules
universal
Griseofulvin
Higher the cholesterol or long saturated fatty acid content
Xeroderma pigmentosum
41. Bind 30S subunit preventing attachment of aminoacyl - tRNA
methionine is only encoded by
nucleosid
Mebendazole/thiabendazole
Tetracyclines
42. Mutation in nucleotide excision repair Dry skin with melanoma and other cancers
Methotrexate
Xeroderma pigmentosum
Cyclins
Post - translational modifications
43. Cilia - glagella - mitotic spindle - neurons - centrioles
microtubule
Steps in splicing
Guanine has a
Enhancer
44. Type III
desmin
What type of collagen is most affected in Ehlers Danlos
Pyrimidines
5FU
45. Does not
Excocytosis of collagen
polyadenylation does/does not require a template
Which end of the nucleotide has the triphosphate
Tumor Suppressors
46. Responsible for the accuracy of amino acid selection
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
intermediate filaments
DNA pol III
Hydroxylation of which amino acids are attached to Glycine to form collagen
47. RER translation of collagen alpha chains (preprocollagen) usually Gly-X-Y
purines
Collagedn synthesis where?
C- G bond
Elastase is inhibited by
48. Negatively charged DNA loops twice around histone octamers create a nucloesome bead.
Order of mitosis
Ehlers Danlos
Common amino acids in elastin
chromatin structure
49. In the nucleus after transcitpion and only processed RNA is transporte out of the nucleus
Elongation
Stable (quiescent)
RNA processing in eukaryotes occurs
Glycosolation
50. Anit helminth - act on microtubules
Mebendazole/thiabendazole
the tRNA- amino acid bond
Thymine has a
nucleotide