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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Genetic code is conserved throughout evolution
Single Strand DNA Repair types
universal
Sodium K ATPase
promoter
2. Read froma fixed starting point as a continous sequenecs of bases
Mebendazole/thiabendazole
Tropocollagen cross links between_____ to form____
commaless - non - overlapping
trimethoprim
3. Stretch of DNA that alters gene expression by binding transcription factors
Elongation
Heterochromatin
Enhancer
Mebendazole/thiabendazole
4. Promoter - enhancer - promoter - TATA- transcription initiation site - coding region (including exons and introns) and then the AATAAA
intermediate filaments
Functional organization of the gene
Single Strand DNA Repair types
Free ribosomes
5. H1 string
What ties teh nucleosome together
Silencer
Promoter mutation
Which end of the tRNA is the amino acid bound to?
6. Faulty collagen synthesis causing 1) hyperextensible skin 2) tendency to bleed 3) hypermobile joints
Ehlers Danlos
Molecular motor protiesn
tRNA activation
The only histone not on the core
7. 5 prime to 3 prime
Higher the cholesterol or long saturated fatty acid content
Chediak Higashi syndrome
mRNA is syntehsized in which direction?
Cell cycle order
8. G1 - S - G2 - Mitosis
Single Strand DNA Repair types
Cell cycle order
DNA pol I
promoter
9. Must be both activated and inactivated for cell cycle to progress
Cyclin - CDK
Euchromatin
purines
chromatin structure
10. Genetic bone disorder (brittle bone disease) type 1 colalgen - fractures (during birth) 2) Blue sclerae 3) hearing loss 4) dental imperfections 1:10000 may be confused with child abuse
Osteogenesis Imperfecta
Permanent cells
Labile
single stranded binding proteinds
11. 75-90 nucleotides - 2ary structure cloverleaf form anticodon end is opposite 3 prime aminoacyl end
commaless - non - overlapping
actin and myosin
Smooth ER
tRNA Structure
12. Microtubule polymerization defect resulting in lowered phagocytosis. results in recurrent pyogenic infections - partial albinism and peripheral neuropathy
tRNA gripping and going places
Chediak Higashi syndrome
Glycosolation
trimethoprim
13. Makes an RNA primer on which DNA polymerase II can initiate replication
Primase
Digoxin (cardiac glycosides)
commaless - non - overlapping
Stable (quiescent)
14. Enter G1 from G0 when stimulated Hepatocytes/lymphocytes
Stable (quiescent)
Steps in splicing
nonsense
Tropocollagen cross links between_____ to form____
15. Anti breast cancer - acts on mts
actin and myosin
Paclitaxil
Kartageners syndrome
hydroxyurea
16. Tansport cellular cargo toward opposite ends of microtubule tracks
Mismatch repair
Collagedn synthesis where?
transversion
Molecular motor protiesn
17. 3 sodium out for 2 potassium in (nout - kin)takes 1 atp and the machine is phosphorylated during the machine cycle
Elastase is inhibited by
DNA topoisomerases
Macrolides
Sodium K ATPase
18. The 5prime end (energy for the bond)
Which end of the nucleotide has the triphosphate
Deamination of cytosine makes
Labile
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
19. Blocks denovo purine synthesis
6MP
Alports syndrome
Loading tRNA on to ribosome energy requirement
the tRNA- amino acid bond
20. ATP
tRNA activation
Oubain
cytokeratin
Aminoacylt - tRNA synthetase
21. Vimentin - desmin - cytockeratin - glial fibrillary acid proteins - neurofilaments
intermediate filaments
purines
Alports syndrome
Cell cycle order
22. Trimming removal of n or c terminal propeptides from zymogens to generate mature proteinds
Post - translational modifications
Exons
Glycosolation
unambiguous
23. Each codon specifies only 1 amino acid
Smooth ER
Order of mitosis
unambiguous
Digoxin (cardiac glycosides)
24. Particular sequnece in genomre where DNA replication begins. May be single (prokaryotes) or multiple (eukaryotes)
Single Strand DNA Repair types
Outside the cell what processing must be done in procolalgen
What type of collagen is most affected in Ehlers Danlos
origin of replication
25. Three amino acids necessary for purine synthesis= glutamine - aspartate and glycine
Gag on pure gold
Total energy expenditure requirement for translocation
mRNA stop codons
chromatin structure
26. Base + ribose
tRNA Structure
nucleosid
Plasma membrane composition
Tropocollagen cross links between_____ to form____
27. Neurons - skeletal - and cardiac muscle - RBCs
Primase
trimethoprim
Example of permanent cells
Mebendazole/thiabendazole
28. Cleave terminal regions of procollagen to transform into insoluable tropocolagen
Paclitaxil
Outside the cell what processing must be done in procolalgen
step two of RNA processing
What type of collagen is most affected in Ehlers Danlos
29. No proofreading function but can initiate chains. RNA poymerase II opens DNA at promoter site
Proofreading function in eukaryotic RNA
5FU
Step one of RNA processing
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
30. Methyl THYmine has a meTHYl
Collagen
methionine is only encoded by
Thymine has a
Paclitaxil
31. Seals
hydroxyurea
DNA ligase
polyadenylation does/does not require a template
Osteogenesis Imperfecta
32. Site of secretory protiens (mucus secreting goblet cells and antibody secreting cells)
Rough ER
mRNA start codons
Common amino acids in elastin
Excocytosis of collagen
33. Change resulting in misreading of all nucleotides downstream - usually resulting in a truncated non functional protien
Base excision repair
Primase
frame shift
Excocytosis of collagen
34. A site - incoming aminoacyl tRNA - Psite accomodates growing Peptide - E site holds EmplytRNA as it exits
Paclitaxil
Neurofilaments
promoter
Going APE
35. Inhibits ribonucleotide reductase
Termination
hydroxyurea
Step Three of RNA processing
Exons
36. RER translation of collagen alpha chains (preprocollagen) usually Gly-X-Y
Macrolides
Initial transcript without processing is known as
Collagedn synthesis where?
Neurofilaments
37. Introns stay In the nucleus whereas EXons EXit and are EXpressed
Plasma membrane composition
Oubain
Where do introns and exons stay
helicase
38. HS1 - HSB - H2 - H4
Immunohistochemical stains vimentin
Cell cycle
histone octamer names
Going APE
39. Remain in G0 regenerate from stem cells
Paclitaxil
Where do introns and exons stay
Permanent cells
Rough ER
40. Methionine - which may be removed before translation is completed
Mebendazole/thiabendazole
Clindamycin
In eukaryotes the starting amino acid is...
pyrimadines
41. The 3 prime hydroxyl of the nascent chain is the target
the tRNA- amino acid bond
Which end of a growing DNA strand is the target
Primase
Initial transcript without processing is known as
42. Antigout - acts on mts
Cholchicine
commaless - non - overlapping
DNA topoisomerases
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
43. Base+ribose+phosphate linked by a phosphodiester bond
Initial transcript without processing is known as
nucleotide
Proteosomal degradation
Mismatch repair
44. 1P (blocked by tetracycline)
Loading tRNA on to ribosome energy requirement
Silencer
A- T
methionine is only encoded by
45. Specific endonucleases release the oligonucleotide containing damaged bases. DNA polymerase and logase fill and resealt eh gap
Nucleotide excision repair
What type of collagen is most affected in Ehlers Danlos
Protein synthesis is in which direction
purines
46. 4 high enrgy bonds
Total energy expenditure requirement for translocation
helicase
Digoxin (cardiac glycosides)
Cell cycle
47. Inhibits 50S peptidyl transferase
Elastin
Chloramphenicol
Associations of Ehlers Danlos
Hereditary non polyposis colorectal cancer
48. The N to C
kinesin
RNA processing in eukaryotes occurs
Protein synthesis is in which direction
Chloramphenicol
49. Neuroglia
GFAP
Gag on pure gold
Excocytosis of collagen
In eukaryotes the starting amino acid is...
50. Binds 50S blocking translocation
Clindamycin
mRNA start codons
Example of permanent cells
Collagedn synthesis where?