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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Cylindrical structure composed of helical array of plymerized dimers of alpha and beta tubulin - flagella - cilia - mitotic spindle - grows slowly collapses quickly
cytokeratin
Base excision repair
microtubule
Where do introns and exons stay
2. Condensed - transciptionally inactive HC- Highly condensed
GFAP
intermediate filaments
Hereditary non polyposis colorectal cancer
Heterochromatin
3. Methyl THYmine has a meTHYl
Alternate splicing
Thymine has a
Replication fork
Example of permanent cells
4. Brings together 2 ends of DNA fragments no requirement for homology
Rough ER
Hereditary non polyposis colorectal cancer
tRNA
Non homologous end joining
5. Cyclin depndent kinases; consituative and inactive
Protein synthesis is in which direction
Cholchicine
DNA ligase
CDKs
6. The 5prime end (energy for the bond)
Vincristine/Vinblastine
Which end of the nucleotide has the triphosphate
transversion
Collagedn synthesis where?
7. Site where negative regulators bind
Cyclins
microtubule
Silencer
In eukaryotes the starting amino acid is...
8. P53 and RB normally inhibit g1 to S progression
Tumor Suppressors
Single Strand DNA Repair types
In eukaryotes the starting amino acid is...
Promoter mutation
9. Neurons - skeletal - and cardiac muscle - RBCs
C- G bond
methionine is only encoded by
mRNA start codons
Example of permanent cells
10. Completed protein is released from ribosme through simple hydrolosis and dissociates
Xeroderma pigmentosum
Double Strand DNA repair
Proofreading function in eukaryotic RNA
Termination
11. (A - G) 2 rings Pure As Gold
Stable (quiescent)
Purines
tRNA gripping and going places
Steps in splicing
12. Splicing out of introns
nucleosid
What does the hydroxylation of proline and lysine require
Step Three of RNA processing
Translocation
13. Greater melting temperature lower fluidity
nucleotide
Chloramphenicol
Higher the cholesterol or long saturated fatty acid content
Rough ER
14. 2 H bonds greater GC content greater melting point
Free ribosomes
purines
Loading tRNA on to ribosome energy requirement
A- T
15. Trimming removal of n or c terminal propeptides from zymogens to generate mature proteinds
Loading tRNA on to ribosome energy requirement
Post - translational modifications
Labile
What type of collagen is most affected in Ehlers Danlos
16. Promoter - enhancer - promoter - TATA- transcription initiation site - coding region (including exons and introns) and then the AATAAA
Which end of the nucleotide has the triphosphate
transition
tRNA aminoacylation
Functional organization of the gene
17. Negatively charged DNA loops twice around histone octamers create a nucloesome bead.
Mismatch repair
Tropocollagen cross links between_____ to form____
intermediate filaments
chromatin structure
18. Stretch of DNA that alters gene expression by binding transcription factors
C- G bond
transition
Enhancer
Prokaryotes
19. Elastase
Collagen
Elastin is broken down by
microtubule
A- T
20. Antifungal - act on microtubules
transition
Griseofulvin
Collagedn synthesis where?
purines
21. The N to C
Guanine has a
Chloramphenicol
Collagen
Protein synthesis is in which direction
22. H1
Stable (quiescent)
Axonemal dyenin
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
The only histone not on the core
23. Uracil
microtubule
Deamination of cytosine makes
universal
Elastase is inhibited by
24. Genetic code is conserved throughout evolution
Paclitaxil
methionine is only encoded by
universal
Methotrexate
25. Commonly results in dramatic decrease in amount of gene transcribed
Promoter mutation
Heterochromatin
Thymine has a
Covalent alterations
26. Exocytose procollagen into extracellylar sace
Non homologous end joining
Excocytosis of collagen
The only histone not on the core
nonsense
27. Strethchy protein within lungs - large artiers - elastic liaments - vocal cords - ligamenta flava)
Prokaryote RNA pol
Tropocollagen cross links between_____ to form____
Elastin
Which end of a growing DNA strand is the target
28. More than 1 codon may code for the same amino acid
Cholchicine
Mismatch repair
degenerate or redundant
Chloramphenicol
29. Phosphorylation - glycosloation - hyderoxylation
What does the hydroxylation of proline and lysine require
Covalent alterations
commaless - non - overlapping
Macrolides
30. Cilia - glagella - mitotic spindle - neurons - centrioles
DNA topoisomerases
microtubule
Common amino acids in elastin
tRNA gripping and going places
31. 3 sodium out for 2 potassium in (nout - kin)takes 1 atp and the machine is phosphorylated during the machine cycle
Sodium K ATPase
Elastase is inhibited by
Prokaryote RNA pol
Outside the cell what processing must be done in procolalgen
32. Inhibits 50S peptidyl transferase
Post - translational modifications
Chloramphenicol
microtubule
origin of replication
33. VItamin C
What does the hydroxylation of proline and lysine require
degenerate or redundant
Neurofilaments
frame shift
34. Inhibit formation of the initation complex and cause misreading of mRNA
Aminoglycosides
tRNA
Collagen
Which end of a growing DNA strand is the target
35. Binds 50S blocking translocation
Clindamycin
Hydroxylation of which amino acids are attached to Glycine to form collagen
Heterochromatin
Plasma membrane composition
36. Poly adenylation
Deamination of cytosine makes
nonsense
step two of RNA processing
Oubain
37. Anti cancer - act on microtubules
Excocytosis of collagen
Guanine has a
Vincristine/Vinblastine
Ehlers Danlos
38. Made from IMP precursor
tRNA aminoacylation
purines
Cyclins
A- T
39. Antigout - acts on mts
polyadenylation does/does not require a template
Step one of RNA processing
Cholchicine
tRNA activation
40. 75-90 nucleotides - 2ary structure cloverleaf form anticodon end is opposite 3 prime aminoacyl end
5FU
microtubule
tRNA Structure
Enhancer
41. Anterograde to microtubule
chromatin structure
mRNA is syntehsized in which direction?
Higher the cholesterol or long saturated fatty acid content
kinesin
42. Inhibits ribonucleotide reductase
hydroxyurea
missense mutation
Where do introns and exons stay
A- T
43. GTP
tRNA gripping and going places
In eukaryotes the starting amino acid is...
Macrolides
Elastin is broken down by
44. Mutation in nucleotide excision repair Dry skin with melanoma and other cancers
pyrimadines
Xeroderma pigmentosum
silent mutation
Kartageners syndrome
45. Prevents stranges from reannealing
single stranded binding proteinds
promoter
AUG codes For what in prokaryotes
Fluoroquinolones
46. A malfunction of mismatch repair (MUt L etc..)
Griseofulvin
Step one of RNA processing
Hereditary non polyposis colorectal cancer
Excocytosis of collagen
47. Microtubule polymerization defect resulting in lowered phagocytosis. results in recurrent pyogenic infections - partial albinism and peripheral neuropathy
White codon is at the 3 prime end of a tRNA
Chediak Higashi syndrome
Paclitaxil
Proofreading function in eukaryotic RNA
48. Immotile cilia due to a dyenin arm defect. Results in male nad female inferticility (sperm immotile) - bronchiectasis - and recurrent sinusisits - associated with situs inversus
Enhancer
tRNA aminoacylation
Kartageners syndrome
Cyclins
49. Base + ribose
microtubule
Neurofilaments
5FU
nucleosid
50. Retrograde to microtubules
dyenin
Cholchicine
Introns
Stable (quiescent)