Test your basic knowledge |

First Aid: Biochemistry Molecular

Subjects : health-sciences, first-aid

Instructions:

Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can study here.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Non homologous end joining
Double Strand DNA repair
Elastase is inhibited by
Promoter mutation
intermediate filaments

2. CCA AT 3 PRIME END
White codon is at the 3 prime end of a tRNA
DNA pol I
DNA topoisomerases
Pyrimidines

3. Inhibits by binding to the potassium side
pyrimadines
Outside the cell what processing must be done in procolalgen
Oubain
RNA polymerases in eukaryotes

4. More than 1 codon may code for the same amino acid
mRNA start codons
DNA pol I
degenerate or redundant
Alports syndrome

5. Ribonucleotide reductase
Purines
Elastin
DNA/RNA/Protein syntesis direction
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by

6. RER translation of collagen alpha chains (preprocollagen) usually Gly-X-Y
Cholchicine
Tropocollagen cross links between_____ to form____
Collagedn synthesis where?
Elastin

7. Specific endonucleases release the oligonucleotide containing damaged bases. DNA polymerase and logase fill and resealt eh gap
Euchromatin
Cell cycle order
Nucleotide excision repair
degenerate or redundant

8. Read froma fixed starting point as a continous sequenecs of bases
Promoter mutation
DNA pol I
unambiguous
commaless - non - overlapping

9. Brings together 2 ends of DNA fragments no requirement for homology
Non homologous end joining
Permanent cells
Where do introns and exons stay
Silencer

10. Immotile cilia due to a dyenin arm defect. Results in male nad female inferticility (sperm immotile) - bronchiectasis - and recurrent sinusisits - associated with situs inversus
unambiguous
Enhancers and silencer may be located_____
Example of permanent cells
Kartageners syndrome

11. Substituting a pyramidine for a pyrimadine
Covalent alterations
Nucleotide excision repair
transition
polyadenylation does/does not require a template

12. Neurons - skeletal - and cardiac muscle - RBCs
Thymine has a
Elastin
Cyclins
Example of permanent cells

13. Contain the actual genetic information coding for protein
Neurofilaments
the tRNA- amino acid bond
Which end of the nucleotide has the triphosphate
Exons

14. Unattached to any membrane; site of cytosolic and organeller prtoeins
Vincristine/Vinblastine
Termination
Free ribosomes
Osteogenesis Imperfecta

15. Lysine/hydroxylysine and combines to form collagen
single stranded binding proteinds
Tropocollagen cross links between_____ to form____
Non homologous end joining
Where do introns and exons stay

16. No proofreading function but can initiate chains. RNA poymerase II opens DNA at promoter site
Proofreading function in eukaryotic RNA
methionine is only encoded by
Immunohistochemical stains vimentin
Which end of the tRNA is the amino acid bound to?

17. Site where negative regulators bind
Silencer
DNA/RNA/Protein syntesis direction
Methotrexate
unambiguous

18. Codes for formyl methionine (f - Met)
AUG codes For what in prokaryotes
capped and tail transcript is called
Initial transcript without processing is known as
Glycosolation

19. UGA - UAG - UAA
mRNA stop codons
commaless - non - overlapping
Protein synthesis initiation
Steps in splicing

20. Made from orogate precuror with PRPP added later
mRNA is syntehsized in which direction?
pyrimadines
Higher the cholesterol or long saturated fatty acid content
Macrolides

21. Site where RNA polymerase and multiple other transciption factors bind to DNA upstream from gene locus (AT rich upstream sequence with TATA and CAAT boxes)
promoter
transversion
degenerate or redundant
Promoter mutation

22. H1
AUG codes For what in prokaryotes
Single Strand DNA Repair types
Chloramphenicol
The only histone not on the core

23. Unmethylated - newly synthesized string is recognized - mismatched nucleotides are removed and the gap is filled and resealed
Cyclins
Elastase is inhibited by
Mismatch repair
Total energy expenditure requirement for translocation

24. Three amino acids necessary for purine synthesis= glutamine - aspartate and glycine
Cyclins
methionine is only encoded by
tRNA aminoacylation
Gag on pure gold

25. Cylindrical structure composed of helical array of plymerized dimers of alpha and beta tubulin - flagella - cilia - mitotic spindle - grows slowly collapses quickly
microtubule
Promoter mutation
Total energy expenditure requirement for translocation
Excocytosis of collagen

26. Hydroxy proline and hydroxylysine
Tetracyclines
Pyrimidines
Hydroxylation of which amino acids are attached to Glycine to form collagen
microtubule

27. Genetic bone disorder (brittle bone disease) type 1 colalgen - fractures (during birth) 2) Blue sclerae 3) hearing loss 4) dental imperfections 1:10000 may be confused with child abuse
chromatin structure
histone octamer names
What does the hydroxylation of proline and lysine require
Osteogenesis Imperfecta

28. The 5prime end (energy for the bond)
Functional organization of the gene
What type of collagen is most affected in Ehlers Danlos
Which end of the nucleotide has the triphosphate
Digoxin (cardiac glycosides)

29. Bm - kidney - ears and eyes
Type IV collagen is an important structural component of...
single stranded binding proteinds
Aminoglycosides
Where do introns and exons stay

30. Methionine - which may be removed before translation is completed
In eukaryotes the starting amino acid is...
kinesin
Non homologous end joining
the tRNA- amino acid bond

31. Anit helminth - act on microtubules
tRNA gripping and going places
Mebendazole/thiabendazole
chromatin structure
Associations of Ehlers Danlos

32. Genetic code is conserved throughout evolution
cytokeratin
universal
GFAP
What does the hydroxylation of proline and lysine require

33. The 3 prime hydroxyl of the nascent chain is the target
Which end of a growing DNA strand is the target
Replication fork
Where do introns and exons stay
Cell cycle order

34. Y shaped region along DNA template where leading and lagging strands are syntehsized
Ehlers Danlos
mRNA start codons
Replication fork
Step one of RNA processing

35. Inhibits bacterials dihydrofolate reducatese down thymine
Base excision repair
RNA polymerases in eukaryotes
trimethoprim
Axonemal dyenin

36. Site of secretory protiens (mucus secreting goblet cells and antibody secreting cells)
Tumor Suppressors
Translocation
the tRNA- amino acid bond
Rough ER

37. ATP
capped and tail transcript is called
tRNA activation
Axonemal dyenin
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon

38. Prokaryotic only. Degrades RNA primer and fills in the gap with DNA (5 prime to 3 prime exonuclease)
mRNA start codons
Prokaryotes
White codon is at the 3 prime end of a tRNA
DNA pol I

39. Unwinds DNA template at replication fork
helicase
Outside the cell what processing must be done in procolalgen
Higher the cholesterol or long saturated fatty acid content
DNA pol III

40. Proline - glycine
Common amino acids in elastin
Proofreading function in eukaryotic RNA
Double Strand DNA repair
tRNA Structure

41. Enter G1 from G0 when stimulated Hepatocytes/lymphocytes
Stable (quiescent)
GFAP
Loading tRNA on to ribosome energy requirement
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by

42. Exocytose procollagen into extracellylar sace
Elongation
Glycosolation
Excocytosis of collagen
Silencer

43. Retrograde to microtubules
Neurofilaments
Chediak Higashi syndrome
Smooth ER
dyenin

44. (A - G) 2 rings Pure As Gold
Tumor Suppressors
microtubule
Purines
chromatin structure

45. Poly adenylation
Clindamycin
Prokaryotes
Enhancers and silencer may be located_____
step two of RNA processing

46. Elastase
Elastin is broken down by
DNA pol I
Euchromatin
CDKs

47. DNA And RNA synthesized in the 5-3 direction
RNA polymerases in eukaryotes
What type of collagen is most affected in Ehlers Danlos
DNA/RNA/Protein syntesis direction
Pyrimidines

48. Particular sequnece in genomre where DNA replication begins. May be single (prokaryotes) or multiple (eukaryotes)
transversion
origin of replication
the tRNA- amino acid bond
Higher the cholesterol or long saturated fatty acid content

49. Prokaryotic only. Elongates leading strand by adding deoxynucleotides to the 3prime end. Elongates laggin strand. 3 prime to 5 prime exonuclease activity
DNA pol III
nucleotide
alpha amintin
Elastin

50. Splicing out of introns
Step Three of RNA processing
alpha amintin
Stable (quiescent)
Clindamycin