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First Aid: Biochemistry Molecular

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Negatively charged DNA loops twice around histone octamers create a nucloesome bead.






2. Lysine/hydroxylysine and combines to form collagen






3. More than 1 codon may code for the same amino acid






4. Close to - far from or even within (in an intron) the gene whose expression it regulates






5. Capping on 5 prime end (7 methylguanosine) -






6. Anit helminth - act on microtubules






7. Trimming removal of n or c terminal propeptides from zymogens to generate mature proteinds






8. Different exons can be combined to make nique protiens in different times






9. Specific glycosylases recognize and remove damaged bases - AP endonuclease cuts DNA at pyrimidne site - empty sugar is removed and the gap is filled and resealed






10. In the nucleus after transcitpion and only processed RNA is transporte out of the nucleus






11. A malfunction of mismatch repair (MUt L etc..)






12. Connective tissue






13. Bm - kidney - ears and eyes






14. AD and AR- associated iwth joint dislocation - berry aneurysms - organ rupture






15. ATP- AMP (2 phosphoanhydride bonds)






16. One codon AUG






17. Prokaryotic only. Degrades RNA primer and fills in the gap with DNA (5 prime to 3 prime exonuclease)






18. Substituting a purine for a pyrimdine or vice versa






19. Epithelial cells






20. Site where RNA polymerase and multiple other transciption factors bind to DNA upstream from gene locus (AT rich upstream sequence with TATA and CAAT boxes)






21. Inhibits thymidylate synthase down thymine






22. 1 RNA polymerase (multisubunite complex) makes all 3 kinds of RNA






23. 1) primary transcript combines with snRNPs and other proteins to form spliceosome 2) lariat shaped intermediate is generated 3) Lariat is removed and released to precisely join 2 exons






24. Introns stay In the nucleus whereas EXons EXit and are EXpressed






25. Proline - glycine






26. Neuroglia






27. Hydroxy proline and hydroxylysine






28. HS1 - HSB - H2 - H4






29. No proofreading function but can initiate chains. RNA poymerase II opens DNA at promoter site






30. Aminoacyl - tRNA binds to A site 2) peptidyltransferase catalyzes peptide bond formation transfers growing polypeptie to amino acid in A site 3) ribosome advances 3 nucleotides toward the 3 prime end of RNA moving peptiydyl RNA to P site






31. Cilia - glagella - mitotic spindle - neurons - centrioles






32. Faulty collagen synthesis causing 1) hyperextensible skin 2) tendency to bleed 3) hypermobile joints






33. 4 high enrgy bonds






34. Completed protein is released from ribosme through simple hydrolosis and dissociates






35. CUT 1 ring Cut the Py






36. Checkpoints control transition between phases of cell cycle. regulated by cyclins - CDKs and tumor suppressors. Mitosis (shortest phse)






37. Ketone






38. Contain the actual genetic information coding for protein






39. Accurate base pairing is required only in the first 2 nucleotide positions of an mRNA so codons differing ht e3rd wobble psoition may code for the same tRNA/amino acid code






40. Promoter - enhancer - promoter - TATA- transcription initiation site - coding region (including exons and introns) and then the AATAAA






41. Microtubule polymerization defect resulting in lowered phagocytosis. results in recurrent pyogenic infections - partial albinism and peripheral neuropathy






42. Mutation in nucleotide excision repair Dry skin with melanoma and other cancers






43. Immotile cilia due to a dyenin arm defect. Results in male nad female inferticility (sperm immotile) - bronchiectasis - and recurrent sinusisits - associated with situs inversus






44. Remain in G0 regenerate from stem cells






45. Site of dteroid synthesis and detoxification of druigs and poisons (liver hepatocytes and steroid horomore adrenal cortex)






46. Attachment of ubiquitin to defective proteinds to tag them for breakdown






47. The 3 prime hydroxyl of the nascent chain is the target






48. Strethchy protein within lungs - large artiers - elastic liaments - vocal cords - ligamenta flava)






49. 9+2 arrangement of microtubules -






50. (A - G) 2 rings Pure As Gold







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