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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Change resulting in early stop codon
transition
Macrolides
6MP
nonsense
2. Methyl THYmine has a meTHYl
Enhancer
Thymine has a
White codon is at the 3 prime end of a tRNA
Where do introns and exons stay
3. Inhibits bacterials dihydrofolate reducatese down thymine
Elastase is inhibited by
trimethoprim
Step one of RNA processing
purines
4. Made from IMP precursor
universal
purines
Kartageners syndrome
Oubain
5. Same aa often base change in 3rd position of codon
Axonemal dyenin
silent mutation
DNA pol I
Which end of the tRNA is the amino acid bound to?
6. VItamin C
nucleosid
Common amino acids in elastin
What does the hydroxylation of proline and lysine require
Initial transcript without processing is known as
7. Condensed - transciptionally inactive HC- Highly condensed
Initial transcript without processing is known as
Heterochromatin
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
Digoxin (cardiac glycosides)
8. 5 prime to 3 prime
tRNA activation
Step Three of RNA processing
methionine is only encoded by
mRNA is syntehsized in which direction?
9. RER translation of collagen alpha chains (preprocollagen) usually Gly-X-Y
Ehlers Danlos
C- G bond
Collagedn synthesis where?
Introns
10. Different exons can be combined to make nique protiens in different times
Aminoglycosides
Labile
Which end of the tRNA is the amino acid bound to?
Alternate splicing
11. Codes for formyl methionine (f - Met)
tRNA activation
What does the hydroxylation of proline and lysine require
GFAP
AUG codes For what in prokaryotes
12. Nucleotide excision repair - Base Excision repair - Mismath repair
Single Strand DNA Repair types
Gag on pure gold
What does the hydroxylation of proline and lysine require
the tRNA- amino acid bond
13. More than 1 codon may code for the same amino acid
Which is the most and least abundant type of RNA
degenerate or redundant
Step Three of RNA processing
Functional organization of the gene
14. Change resulting in misreading of all nucleotides downstream - usually resulting in a truncated non functional protien
frame shift
Neurofilaments
Elastin is broken down by
Cyclins
15. Non homologous end joining
Going APE
Molecular motor protiesn
Hydroxylation of which amino acids are attached to Glycine to form collagen
Double Strand DNA repair
16. Microtubule polymerization defect resulting in lowered phagocytosis. results in recurrent pyogenic infections - partial albinism and peripheral neuropathy
Prokaryote RNA pol
nucleosid
Free ribosomes
Chediak Higashi syndrome
17. Splicing out of introns
Common amino acids in elastin
Purines
chromatin structure
Step Three of RNA processing
18. Poly adenylation
Hydroxylation of which amino acids are attached to Glycine to form collagen
Clindamycin
Prokaryote RNA pol
step two of RNA processing
19. Faulty collagen synthesis causing 1) hyperextensible skin 2) tendency to bleed 3) hypermobile joints
Where do introns and exons stay
Ehlers Danlos
DNA pol III
hydroxyurea
20. Base+ribose+phosphate linked by a phosphodiester bond
nucleotide
purines
DNA ligase
Functional organization of the gene
21. Inhbits RNA pol II (found in death cap mushrooms)
cytokeratin
alpha amintin
Translocation
Neurofilaments
22. Be So Totatally Cool Read Books (bOne - CarTWOlage - Threeticular - Type IV under the floor)
Collagen
Loading tRNA on to ribosome energy requirement
Prokaryotes
Xeroderma pigmentosum
23. HS1 - HSB - H2 - H4
Exons
Ehlers Danlos
Gag on pure gold
histone octamer names
24. The 3 prime end
Silencer
Associations of Ehlers Danlos
Tumor Suppressors
Which end of the tRNA is the amino acid bound to?
25. Capping on 5 prime end (7 methylguanosine) -
Aminoacylt - tRNA synthetase
Step one of RNA processing
Molecular motor protiesn
Alternate splicing
26. A site - incoming aminoacyl tRNA - Psite accomodates growing Peptide - E site holds EmplytRNA as it exits
GFAP
Step one of RNA processing
Going APE
Collagedn synthesis where?
27. Genetic code is conserved throughout evolution
transversion
desmin
universal
Neurofilaments
28. H1
Elastase is inhibited by
The only histone not on the core
transition
Eukaroytes
29. Inhibits the atpase which increases intracellular sodium which increases intracellular calcium increases cardiaccontractility
Enhancers and silencer may be located_____
Proofreading function in eukaryotic RNA
Prokaryotes
Digoxin (cardiac glycosides)
30. Connective tissue
Immunohistochemical stains vimentin
frame shift
A- T
Going APE
31. Specific glycosylases recognize and remove damaged bases - AP endonuclease cuts DNA at pyrimidne site - empty sugar is removed and the gap is filled and resealed
Which is the most and least abundant type of RNA
nonsense
Base excision repair
Enhancers and silencer may be located_____
32. Neuroglia
microtubule
GFAP
Outside the cell what processing must be done in procolalgen
Neurofilaments
33. Enter G1 from G0 when stimulated Hepatocytes/lymphocytes
Double Strand DNA repair
What does the hydroxylation of proline and lysine require
Stable (quiescent)
Proteosomal degradation
34. Inhibits dihydrofolate reductase down thymine
Methotrexate
Rough ER
Collagen
chromatin structure
35. Blocks denovo purine synthesis
Ehlers Danlos
6MP
Clindamycin
Loading tRNA on to ribosome energy requirement
36. Aminoacyl - tRNA binds to A site 2) peptidyltransferase catalyzes peptide bond formation transfers growing polypeptie to amino acid in A site 3) ribosome advances 3 nucleotides toward the 3 prime end of RNA moving peptiydyl RNA to P site
Griseofulvin
Elongation
Aminoacylt - tRNA synthetase
Proteosomal degradation
37. Hn RNA
Post - translational modifications
C- G bond
Initial transcript without processing is known as
Purines
38. Phosphorylation - glycosloation - hyderoxylation
Step Three of RNA processing
Covalent alterations
White codon is at the 3 prime end of a tRNA
alpha amintin
39. Regulatory proteins that control cell cycle events; phase specific; activated CDKs
Cyclins
What does the hydroxylation of proline and lysine require
Purines
Enhancers and silencer may be located_____
40. Inhibits ribonucleotide reductase
polyadenylation does/does not require a template
nucleosid
hydroxyurea
Which is the most and least abundant type of RNA
41. Proline - glycine
Elastin is broken down by
Enhancer
Common amino acids in elastin
Alports syndrome
42. Site of dteroid synthesis and detoxification of druigs and poisons (liver hepatocytes and steroid horomore adrenal cortex)
Covalent alterations
Smooth ER
A- T
Cyclins
43. Neurons - skeletal - and cardiac muscle - RBCs
Immunohistochemical stains vimentin
trimethoprim
Example of permanent cells
helicase
44. Unmethylated - newly synthesized string is recognized - mismatched nucleotides are removed and the gap is filled and resealed
Macrolides
methionine is only encoded by
Tropocollagen cross links between_____ to form____
Mismatch repair
45. Introns stay In the nucleus whereas EXons EXit and are EXpressed
Where do introns and exons stay
Promoter mutation
Fluoroquinolones
Enhancers and silencer may be located_____
46. Elastase
Base excision repair
microtubule
Sodium K ATPase
Elastin is broken down by
47. Specific endonucleases release the oligonucleotide containing damaged bases. DNA polymerase and logase fill and resealt eh gap
nonsense
nucleotide
Nucleotide excision repair
Which end of a growing DNA strand is the target
48. Trimming removal of n or c terminal propeptides from zymogens to generate mature proteinds
capped and tail transcript is called
desmin
Post - translational modifications
Nucleotide excision repair
49. Antigout - acts on mts
Cholchicine
the tRNA- amino acid bond
frame shift
Tropocollagen cross links between_____ to form____
50. Genetic bone disorder (brittle bone disease) type 1 colalgen - fractures (during birth) 2) Blue sclerae 3) hearing loss 4) dental imperfections 1:10000 may be confused with child abuse
Osteogenesis Imperfecta
CDKs
Glycosolation
Higher the cholesterol or long saturated fatty acid content