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First Aid: Biochemistry Molecular

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Genetic code is conserved throughout evolution






2. Read froma fixed starting point as a continous sequenecs of bases






3. Stretch of DNA that alters gene expression by binding transcription factors






4. Promoter - enhancer - promoter - TATA- transcription initiation site - coding region (including exons and introns) and then the AATAAA






5. H1 string






6. Faulty collagen synthesis causing 1) hyperextensible skin 2) tendency to bleed 3) hypermobile joints






7. 5 prime to 3 prime






8. G1 - S - G2 - Mitosis






9. Must be both activated and inactivated for cell cycle to progress






10. Genetic bone disorder (brittle bone disease) type 1 colalgen - fractures (during birth) 2) Blue sclerae 3) hearing loss 4) dental imperfections 1:10000 may be confused with child abuse






11. 75-90 nucleotides - 2ary structure cloverleaf form anticodon end is opposite 3 prime aminoacyl end






12. Microtubule polymerization defect resulting in lowered phagocytosis. results in recurrent pyogenic infections - partial albinism and peripheral neuropathy






13. Makes an RNA primer on which DNA polymerase II can initiate replication






14. Enter G1 from G0 when stimulated Hepatocytes/lymphocytes






15. Anti breast cancer - acts on mts






16. Tansport cellular cargo toward opposite ends of microtubule tracks






17. 3 sodium out for 2 potassium in (nout - kin)takes 1 atp and the machine is phosphorylated during the machine cycle






18. The 5prime end (energy for the bond)






19. Blocks denovo purine synthesis






20. ATP






21. Vimentin - desmin - cytockeratin - glial fibrillary acid proteins - neurofilaments






22. Trimming removal of n or c terminal propeptides from zymogens to generate mature proteinds






23. Each codon specifies only 1 amino acid






24. Particular sequnece in genomre where DNA replication begins. May be single (prokaryotes) or multiple (eukaryotes)






25. Three amino acids necessary for purine synthesis= glutamine - aspartate and glycine






26. Base + ribose






27. Neurons - skeletal - and cardiac muscle - RBCs






28. Cleave terminal regions of procollagen to transform into insoluable tropocolagen






29. No proofreading function but can initiate chains. RNA poymerase II opens DNA at promoter site






30. Methyl THYmine has a meTHYl






31. Seals






32. Site of secretory protiens (mucus secreting goblet cells and antibody secreting cells)






33. Change resulting in misreading of all nucleotides downstream - usually resulting in a truncated non functional protien






34. A site - incoming aminoacyl tRNA - Psite accomodates growing Peptide - E site holds EmplytRNA as it exits






35. Inhibits ribonucleotide reductase






36. RER translation of collagen alpha chains (preprocollagen) usually Gly-X-Y






37. Introns stay In the nucleus whereas EXons EXit and are EXpressed






38. HS1 - HSB - H2 - H4






39. Remain in G0 regenerate from stem cells






40. Methionine - which may be removed before translation is completed






41. The 3 prime hydroxyl of the nascent chain is the target






42. Antigout - acts on mts






43. Base+ribose+phosphate linked by a phosphodiester bond






44. 1P (blocked by tetracycline)






45. Specific endonucleases release the oligonucleotide containing damaged bases. DNA polymerase and logase fill and resealt eh gap






46. 4 high enrgy bonds






47. Inhibits 50S peptidyl transferase






48. The N to C






49. Neuroglia






50. Binds 50S blocking translocation