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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Site of dteroid synthesis and detoxification of druigs and poisons (liver hepatocytes and steroid horomore adrenal cortex)
Gag on pure gold
tRNA gripping and going places
Going APE
Smooth ER
2. Inhibits dihydrofolate reductase down thymine
Associations of Ehlers Danlos
Methotrexate
mRNA start codons
microtubule
3. Anterograde to microtubule
transition
kinesin
Smooth ER
missense mutation
4. Specific glycosylases recognize and remove damaged bases - AP endonuclease cuts DNA at pyrimidne site - empty sugar is removed and the gap is filled and resealed
Collagedn synthesis where?
alpha amintin
RNA polymerases in eukaryotes
Base excision repair
5. GTP
Outside the cell what processing must be done in procolalgen
Tumor Suppressors
tRNA gripping and going places
Protein synthesis is in which direction
6. Inhibits bacterials dihydrofolate reducatese down thymine
trimethoprim
What ties teh nucleosome together
Mebendazole/thiabendazole
Non homologous end joining
7. Microvilli - muscle contraction - cytokinesis - adhering juntions
Associations of Ehlers Danlos
Mismatch repair
actin and myosin
Initial transcript without processing is known as
8. 75-90 nucleotides - 2ary structure cloverleaf form anticodon end is opposite 3 prime aminoacyl end
Chediak Higashi syndrome
tRNA Structure
6MP
Fluoroquinolones
9. Inhbits RNA pol II (found in death cap mushrooms)
Protein synthesis initiation
Elastin is broken down by
alpha amintin
microtubule
10. A malfunction of mismatch repair (MUt L etc..)
DNA ligase
Hereditary non polyposis colorectal cancer
Free ribosomes
GFAP
11. The 3 prime hydroxyl of the nascent chain is the target
Enhancers and silencer may be located_____
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
Which end of a growing DNA strand is the target
mRNA start codons
12. Same aa often base change in 3rd position of codon
silent mutation
Gag on pure gold
Protein synthesis initiation
Which end of the nucleotide has the triphosphate
13. Site where negative regulators bind
Permanent cells
Griseofulvin
What ties teh nucleosome together
Silencer
14. Substituting a pyramidine for a pyrimadine
CDKs
transition
DNA pol I
tRNA
15. Nucleotide excision repair - Base Excision repair - Mismath repair
Single Strand DNA Repair types
Methotrexate
Which end of a growing DNA strand is the target
Protein synthesis is in which direction
16. Uracil
C- G bond
Heterochromatin
Chloramphenicol
Deamination of cytosine makes
17. Asymmetric fluid bilayer - contains - cholesterol - phospholipids - sphingoplipids - glycolipids - and protiends
Plasma membrane composition
Xeroderma pigmentosum
Exons
Alports syndrome
18. Made from IMP precursor
Introns
purines
Mismatch repair
Protein synthesis initiation
19. Activated by GTP hydrolosis initiation factors help assembel the 40 S ribosomal subunites with the initiatior tRNA and are released whent he mRNA and the ribosomal subunit assemple with the complex
tRNA activation
Promoter mutation
transversion
Protein synthesis initiation
20. Anit helminth - act on microtubules
polyadenylation does/does not require a template
Mebendazole/thiabendazole
Kartageners syndrome
Heterochromatin
21. ATP- AMP (2 phosphoanhydride bonds)
pyrimadines
Griseofulvin
Stable (quiescent)
tRNA aminoacylation
22. ATP
tRNA activation
Cilia structure
alpha amintin
White codon is at the 3 prime end of a tRNA
23. Retrograde to microtubules
dyenin
Where do introns and exons stay
DNA ligase
5FU
24. 1 RNA polymerase (multisubunite complex) makes all 3 kinds of RNA
Tetracyclines
Prokaryote RNA pol
mRNA start codons
Base excision repair
25. Rampant - Massive - TIny rRNA is most common - then mRNA and then tRNA
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
Rough ER
Which is the most and least abundant type of RNA
nucleosid
26. Promoter - enhancer - promoter - TATA- transcription initiation site - coding region (including exons and introns) and then the AATAAA
Functional organization of the gene
Osteogenesis Imperfecta
Cholchicine
Kartageners syndrome
27. Neuroglia
GFAP
Which is the most and least abundant type of RNA
DNA pol III
Smooth ER
28. Connective tissue
helicase
Immunohistochemical stains vimentin
Common amino acids in elastin
Steps in splicing
29. HS1 - HSB - H2 - H4
commaless - non - overlapping
Type IV collagen is an important structural component of...
The only histone not on the core
histone octamer names
30. Y shaped region along DNA template where leading and lagging strands are syntehsized
Elastin is broken down by
Replication fork
In eukaryotes the starting amino acid is...
trimethoprim
31. Genetic code is conserved throughout evolution
The only histone not on the core
Elastin is broken down by
universal
Prokaryote RNA pol
32. The 5prime end (energy for the bond)
What ties teh nucleosome together
Which end of the nucleotide has the triphosphate
Macrolides
Prokaryotes
33. Inhibit formation of the initation complex and cause misreading of mRNA
Aminoglycosides
Hydroxylation of which amino acids are attached to Glycine to form collagen
Vincristine/Vinblastine
Proteosomal degradation
34. Remain in G0 regenerate from stem cells
Glycosolation
Step Three of RNA processing
Permanent cells
Stable (quiescent)
35. Methyl THYmine has a meTHYl
Replication fork
nonsense
Exons
Thymine has a
36. The N to C
Protein synthesis is in which direction
Kartageners syndrome
Elongation
Prokaryotes
37. AUG inAUGurates protein synthesis
DNA pol I
mRNA start codons
transversion
Collagedn synthesis where?
38. Stretch of DNA that alters gene expression by binding transcription factors
chromatin structure
Steps in splicing
Hydroxylation of which amino acids are attached to Glycine to form collagen
Enhancer
39. Different exons can be combined to make nique protiens in different times
Common amino acids in elastin
Prokaryote RNA pol
Alternate splicing
Permanent cells
40. RNA polymerase I makes rRNA - RNA pol II makes mRNA - RNA pol III makes tRNA
RNA polymerases in eukaryotes
tRNA activation
The only histone not on the core
Excocytosis of collagen
41. Splicing out of introns
transition
Cyclin - CDK
Step Three of RNA processing
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
42. Inhibits thymidylate synthase down thymine
Total energy expenditure requirement for translocation
Which end of the tRNA is the amino acid bound to?
5FU
Molecular motor protiesn
43. Anti breast cancer - acts on mts
commaless - non - overlapping
tRNA
unambiguous
Paclitaxil
44. CCA AT 3 PRIME END
Pyrimidines
Chloramphenicol
White codon is at the 3 prime end of a tRNA
mRNA is syntehsized in which direction?
45. MRNA
Step one of RNA processing
Loading tRNA on to ribosome energy requirement
capped and tail transcript is called
nonsense
46. Does not
Which end of a growing DNA strand is the target
tRNA activation
Step one of RNA processing
polyadenylation does/does not require a template
47. P53 and RB normally inhibit g1 to S progression
Free ribosomes
Tumor Suppressors
Which end of a growing DNA strand is the target
Single Strand DNA Repair types
48. Inhibits ribonucleotide reductase
tRNA Structure
Heterochromatin
Higher the cholesterol or long saturated fatty acid content
hydroxyurea
49. Even 40S 60S =80S
Which end of the nucleotide has the triphosphate
Xeroderma pigmentosum
Eukaroytes
Tetracyclines
50. Seals
Clindamycin
DNA ligase
Heterochromatin
Loading tRNA on to ribosome energy requirement