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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Accurate base pairing is required only in the first 2 nucleotide positions of an mRNA so codons differing ht e3rd wobble psoition may code for the same tRNA/amino acid code
Mebendazole/thiabendazole
tRNA
Purines
Enhancers and silencer may be located_____
2. RNA polymerase I makes rRNA - RNA pol II makes mRNA - RNA pol III makes tRNA
RNA polymerases in eukaryotes
Translocation
Neurofilaments
mRNA start codons
3. Microvilli - muscle contraction - cytokinesis - adhering juntions
Collagen
Where do introns and exons stay
actin and myosin
RNA processing in eukaryotes occurs
4. Scrutinizes aa before and after it binds to tRNA. If incorrect bond is hydrolyzed.
frame shift
transition
Nucleotide excision repair
Aminoacylt - tRNA synthetase
5. Stretch of DNA that alters gene expression by binding transcription factors
Plasma membrane composition
Mismatch repair
Enhancer
Step one of RNA processing
6. Seals
cytokeratin
What type of collagen is most affected in Ehlers Danlos
Mismatch repair
DNA ligase
7. MRNA
origin of replication
capped and tail transcript is called
actin and myosin
Exons
8. Uracil
Which end of the tRNA is the amino acid bound to?
Alports syndrome
Deamination of cytosine makes
Kartageners syndrome
9. Never go to Go divide rapidly with short G1 bone marrow - gut epithelium - skin - hair follicles
dyenin
Outside the cell what processing must be done in procolalgen
DNA ligase
Labile
10. Cleave terminal regions of procollagen to transform into insoluable tropocolagen
Introns
Outside the cell what processing must be done in procolalgen
mRNA is syntehsized in which direction?
A- T
11. Attachment of ubiquitin to defective proteinds to tag them for breakdown
Immunohistochemical stains vimentin
the tRNA- amino acid bond
Proteosomal degradation
GFAP
12. 3 H bonds
capped and tail transcript is called
C- G bond
Eukaroytes
single stranded binding proteinds
13. Rampant - Massive - TIny rRNA is most common - then mRNA and then tRNA
Which end of the tRNA is the amino acid bound to?
Double Strand DNA repair
Which is the most and least abundant type of RNA
DNA pol III
14. Substituting a purine for a pyrimdine or vice versa
Proofreading function in eukaryotic RNA
Elongation
transversion
Primase
15. HS1 - HSB - H2 - H4
histone octamer names
DNA topoisomerases
What does the hydroxylation of proline and lysine require
actin and myosin
16. Odd 30S plus 50 S=70S
C- G bond
tRNA gripping and going places
Prokaryotes
Common amino acids in elastin
17. Remain in G0 regenerate from stem cells
Permanent cells
Mebendazole/thiabendazole
Ehlers Danlos
methionine is only encoded by
18. Lysine/hydroxylysine and combines to form collagen
Cyclin - CDK
Tropocollagen cross links between_____ to form____
Proofreading function in eukaryotic RNA
histone octamer names
19. Inhibit DNA gyrase (specific prokaryotic topoisomerase)
Which is the most and least abundant type of RNA
Rough ER
Fluoroquinolones
universal
20. Methionine - which may be removed before translation is completed
Cell cycle order
In eukaryotes the starting amino acid is...
Cyclins
Elongation
21. Prokaryotic only. Elongates leading strand by adding deoxynucleotides to the 3prime end. Elongates laggin strand. 3 prime to 5 prime exonuclease activity
What type of collagen is most affected in Ehlers Danlos
histone octamer names
AUG codes For what in prokaryotes
DNA pol III
22. Intervening noncoding segments of DNA
Termination
Cilia structure
Cholchicine
Introns
23. Inhibits thymidylate synthase down thymine
5FU
Higher the cholesterol or long saturated fatty acid content
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
CDKs
24. Xlinked recessive IV collagen bm - kidney - ear and eye -- nephritis and defness ocular disturbances
Step Three of RNA processing
nucleotide
Alports syndrome
In eukaryotes the starting amino acid is...
25. Genetic bone disorder (brittle bone disease) type 1 colalgen - fractures (during birth) 2) Blue sclerae 3) hearing loss 4) dental imperfections 1:10000 may be confused with child abuse
Clindamycin
kinesin
Osteogenesis Imperfecta
Base excision repair
26. H1
The only histone not on the core
Example of permanent cells
Pyrimidines
origin of replication
27. Capping on 5 prime end (7 methylguanosine) -
Step one of RNA processing
What type of collagen is most affected in Ehlers Danlos
Protein synthesis initiation
step two of RNA processing
28. 9+2 arrangement of microtubules -
Cilia structure
Which end of the nucleotide has the triphosphate
intermediate filaments
Collagen
29. ATP ase that links peripheral 9 doublets and causes bending of cilium by differential sliding of doublets
Neurofilaments
cytokeratin
Guanine has a
Axonemal dyenin
30. UGA - UAG - UAA
Step Three of RNA processing
mRNA stop codons
Vincristine/Vinblastine
Nucleotide excision repair
31. Anti cancer - act on microtubules
Vincristine/Vinblastine
Deamination of cytosine makes
What does the hydroxylation of proline and lysine require
Protein synthesis is in which direction
32. 5 prime to 3 prime
C- G bond
mRNA is syntehsized in which direction?
Protein synthesis is in which direction
In eukaryotes the starting amino acid is...
33. Must be both activated and inactivated for cell cycle to progress
Xeroderma pigmentosum
Free ribosomes
Cyclin - CDK
chromatin structure
34. Close to - far from or even within (in an intron) the gene whose expression it regulates
Enhancers and silencer may be located_____
helicase
Immunohistochemical stains vimentin
Stable (quiescent)
35. RER translation of collagen alpha chains (preprocollagen) usually Gly-X-Y
Immunohistochemical stains vimentin
Termination
Introns
Collagedn synthesis where?
36. Activated by GTP hydrolosis initiation factors help assembel the 40 S ribosomal subunites with the initiatior tRNA and are released whent he mRNA and the ribosomal subunit assemple with the complex
Going APE
Exons
Thymine has a
Protein synthesis initiation
37. 2 H bonds greater GC content greater melting point
Associations of Ehlers Danlos
kinesin
Protein synthesis is in which direction
A- T
38. Elastase
frame shift
Enhancer
Post - translational modifications
Elastin is broken down by
39. 1) primary transcript combines with snRNPs and other proteins to form spliceosome 2) lariat shaped intermediate is generated 3) Lariat is removed and released to precisely join 2 exons
What type of collagen is most affected in Ehlers Danlos
Collagen
Kartageners syndrome
Steps in splicing
40. Proline - glycine
Type IV collagen is an important structural component of...
Common amino acids in elastin
capped and tail transcript is called
Neurofilaments
41. Inhibits the atpase which increases intracellular sodium which increases intracellular calcium increases cardiaccontractility
Associations of Ehlers Danlos
The only histone not on the core
transversion
Digoxin (cardiac glycosides)
42. Vimentin - desmin - cytockeratin - glial fibrillary acid proteins - neurofilaments
Permanent cells
Elongation
intermediate filaments
Gag on pure gold
43. CUT 1 ring Cut the Py
Stable (quiescent)
Pyrimidines
Cilia structure
Hereditary non polyposis colorectal cancer
44. AD and AR- associated iwth joint dislocation - berry aneurysms - organ rupture
In eukaryotes the starting amino acid is...
Collagen
Associations of Ehlers Danlos
Thymine has a
45. Negatively charged DNA loops twice around histone octamers create a nucloesome bead.
GFAP
chromatin structure
Silencer
Permanent cells
46. Site where negative regulators bind
GFAP
Xeroderma pigmentosum
intermediate filaments
Silencer
47. Does not
polyadenylation does/does not require a template
Exons
In eukaryotes the starting amino acid is...
Heterochromatin
48. Faulty collagen synthesis causing 1) hyperextensible skin 2) tendency to bleed 3) hypermobile joints
5FU
Smooth ER
Ehlers Danlos
nonsense
49. Cilia - glagella - mitotic spindle - neurons - centrioles
unambiguous
Termination
microtubule
capped and tail transcript is called
50. Changed aaconservative - new aa is similar in chemical structure
DNA pol III
Thymine has a
missense mutation
Silencer