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First Aid: Biochemistry Molecular

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Xlinked recessive IV collagen bm - kidney - ear and eye -- nephritis and defness ocular disturbances






2. Odd 30S plus 50 S=70S






3. Inhibit formation of the initation complex and cause misreading of mRNA






4. Greater melting temperature lower fluidity






5. ATP






6. Condensed - transciptionally inactive HC- Highly condensed






7. The 5prime end (energy for the bond)






8. Blocks denovo purine synthesis






9. Connective tissue






10. RNA polymerase I makes rRNA - RNA pol II makes mRNA - RNA pol III makes tRNA






11. Hn RNA






12. H1






13. RER translation of collagen alpha chains (preprocollagen) usually Gly-X-Y






14. Inhibits dihydrofolate reductase down thymine






15. Retrograde to microtubules






16. GTP






17. Inhibits ribonucleotide reductase






18. Trimming removal of n or c terminal propeptides from zymogens to generate mature proteinds






19. Muscle






20. Genetic bone disorder (brittle bone disease) type 1 colalgen - fractures (during birth) 2) Blue sclerae 3) hearing loss 4) dental imperfections 1:10000 may be confused with child abuse






21. Particular sequnece in genomre where DNA replication begins. May be single (prokaryotes) or multiple (eukaryotes)






22. Three amino acids necessary for purine synthesis= glutamine - aspartate and glycine






23. Strethchy protein within lungs - large artiers - elastic liaments - vocal cords - ligamenta flava)






24. Immotile cilia due to a dyenin arm defect. Results in male nad female inferticility (sperm immotile) - bronchiectasis - and recurrent sinusisits - associated with situs inversus






25. Close to - far from or even within (in an intron) the gene whose expression it regulates






26. Elastase






27. Type III






28. Base+ribose+phosphate linked by a phosphodiester bond






29. Unmethylated - newly synthesized string is recognized - mismatched nucleotides are removed and the gap is filled and resealed






30. The 3 prime end






31. Be So Totatally Cool Read Books (bOne - CarTWOlage - Threeticular - Type IV under the floor)






32. Capping on 5 prime end (7 methylguanosine) -






33. Anti breast cancer - acts on mts






34. CUT 1 ring Cut the Py






35. Activated by GTP hydrolosis initiation factors help assembel the 40 S ribosomal subunites with the initiatior tRNA and are released whent he mRNA and the ribosomal subunit assemple with the complex






36. Substituting a pyramidine for a pyrimadine






37. Contain the actual genetic information coding for protein






38. Cyclin depndent kinases; consituative and inactive






39. Methyl THYmine has a meTHYl






40. Attachment of ubiquitin to defective proteinds to tag them for breakdown






41. 1) primary transcript combines with snRNPs and other proteins to form spliceosome 2) lariat shaped intermediate is generated 3) Lariat is removed and released to precisely join 2 exons






42. Seals






43. Site of dteroid synthesis and detoxification of druigs and poisons (liver hepatocytes and steroid horomore adrenal cortex)






44. Completed protein is released from ribosme through simple hydrolosis and dissociates






45. Checkpoints control transition between phases of cell cycle. regulated by cyclins - CDKs and tumor suppressors. Mitosis (shortest phse)






46. UGA - UAG - UAA






47. 5 prime to 3 prime






48. The 3 prime hydroxyl of the nascent chain is the target






49. ATP- AMP (2 phosphoanhydride bonds)






50. Remain in G0 regenerate from stem cells