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Test your basic knowledge |
First Aid: Biochemistry Molecular
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Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
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study here
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Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Retrograde to microtubules
tRNA Structure
dyenin
Step one of RNA processing
Xeroderma pigmentosum
2. Substituting a pyramidine for a pyrimadine
polyadenylation does/does not require a template
Rough ER
transition
CDKs
3. Create a nick in the helix to relieve supercoils created during replication
What does the hydroxylation of proline and lysine require
Protein synthesis is in which direction
DNA topoisomerases
Step one of RNA processing
4. Aminoacyl - tRNA binds to A site 2) peptidyltransferase catalyzes peptide bond formation transfers growing polypeptie to amino acid in A site 3) ribosome advances 3 nucleotides toward the 3 prime end of RNA moving peptiydyl RNA to P site
Non homologous end joining
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
Sodium K ATPase
Elongation
5. Inhibit formation of the initation complex and cause misreading of mRNA
5FU
Aminoglycosides
Proofreading function in eukaryotic RNA
Cholchicine
6. Neuroglia
Prokaryotes
Osteogenesis Imperfecta
Free ribosomes
GFAP
7. Intervening noncoding segments of DNA
Cyclins
tRNA gripping and going places
Introns
Common amino acids in elastin
8. Site where negative regulators bind
silent mutation
Osteogenesis Imperfecta
histone octamer names
Silencer
9. Change resulting in early stop codon
Example of permanent cells
tRNA activation
nonsense
Hydroxylation of which amino acids are attached to Glycine to form collagen
10. You glyucosolate hte pro - alpha chain lysine resudens and form procollagen (triple helix of alpha chains)
microtubule
6MP
Glycosolation
Rough ER
11. Phosphorylation - glycosloation - hyderoxylation
Which end of the tRNA is the amino acid bound to?
Glycosolation
Covalent alterations
transversion
12. H1 string
mRNA is syntehsized in which direction?
White codon is at the 3 prime end of a tRNA
Fluoroquinolones
What ties teh nucleosome together
13. AD and AR- associated iwth joint dislocation - berry aneurysms - organ rupture
Chloramphenicol
Cyclin - CDK
6MP
Associations of Ehlers Danlos
14. Y shaped region along DNA template where leading and lagging strands are syntehsized
hydroxyurea
Replication fork
silent mutation
chromatin structure
15. Substituting a purine for a pyrimdine or vice versa
commaless - non - overlapping
transversion
missense mutation
universal
16. 1 RNA polymerase (multisubunite complex) makes all 3 kinds of RNA
Prokaryote RNA pol
Introns
Order of mitosis
In eukaryotes the starting amino acid is...
17. Ketone
tRNA Structure
polyadenylation does/does not require a template
Guanine has a
transversion
18. Unmethylated - newly synthesized string is recognized - mismatched nucleotides are removed and the gap is filled and resealed
Glycosolation
Mismatch repair
Cilia structure
Free ribosomes
19. Does not
Mebendazole/thiabendazole
polyadenylation does/does not require a template
missense mutation
Higher the cholesterol or long saturated fatty acid content
20. Remain in G0 regenerate from stem cells
Protein synthesis is in which direction
Permanent cells
Exons
Loading tRNA on to ribosome energy requirement
21. Trimming removal of n or c terminal propeptides from zymogens to generate mature proteinds
DNA/RNA/Protein syntesis direction
In eukaryotes the starting amino acid is...
Post - translational modifications
5FU
22. Splicing out of introns
Vincristine/Vinblastine
Step Three of RNA processing
Nucleotide excision repair
Protein synthesis is in which direction
23. Mutation in nucleotide excision repair Dry skin with melanoma and other cancers
silent mutation
Xeroderma pigmentosum
desmin
Mismatch repair
24. Nucleotide excision repair - Base Excision repair - Mismath repair
nonsense
Single Strand DNA Repair types
Rough ER
Oubain
25. RER translation of collagen alpha chains (preprocollagen) usually Gly-X-Y
degenerate or redundant
Elastin is broken down by
Promoter mutation
Collagedn synthesis where?
26. Asymmetric fluid bilayer - contains - cholesterol - phospholipids - sphingoplipids - glycolipids - and protiends
Introns
Plasma membrane composition
step two of RNA processing
Tumor Suppressors
27. Site where RNA polymerase and multiple other transciption factors bind to DNA upstream from gene locus (AT rich upstream sequence with TATA and CAAT boxes)
dyenin
Steps in splicing
promoter
Deamination of cytosine makes
28. Completed protein is released from ribosme through simple hydrolosis and dissociates
tRNA
Oubain
Termination
RNA polymerases in eukaryotes
29. 4 high enrgy bonds
Which end of a growing DNA strand is the target
Total energy expenditure requirement for translocation
nucleosid
Tropocollagen cross links between_____ to form____
30. Unwinds DNA template at replication fork
Fluoroquinolones
GFAP
helicase
Protein synthesis is in which direction
31. Commonly results in dramatic decrease in amount of gene transcribed
commaless - non - overlapping
Chloramphenicol
Promoter mutation
C- G bond
32. Xlinked recessive IV collagen bm - kidney - ear and eye -- nephritis and defness ocular disturbances
Permanent cells
Purines
Paclitaxil
Alports syndrome
33. Neurons - skeletal - and cardiac muscle - RBCs
Example of permanent cells
Order of mitosis
Double Strand DNA repair
Promoter mutation
34. Non homologous end joining
Griseofulvin
Immunohistochemical stains vimentin
Osteogenesis Imperfecta
Double Strand DNA repair
35. Brings together 2 ends of DNA fragments no requirement for homology
C- G bond
White codon is at the 3 prime end of a tRNA
Non homologous end joining
commaless - non - overlapping
36. 75-90 nucleotides - 2ary structure cloverleaf form anticodon end is opposite 3 prime aminoacyl end
origin of replication
tRNA Structure
Cyclin - CDK
Post - translational modifications
37. Accurate base pairing is required only in the first 2 nucleotide positions of an mRNA so codons differing ht e3rd wobble psoition may code for the same tRNA/amino acid code
Cyclin - CDK
tRNA
Protein synthesis initiation
Aminoacylt - tRNA synthetase
38. Faulty collagen synthesis causing 1) hyperextensible skin 2) tendency to bleed 3) hypermobile joints
kinesin
Ehlers Danlos
Primase
Base excision repair
39. 9+2 arrangement of microtubules -
Translocation
Associations of Ehlers Danlos
Neurofilaments
Cilia structure
40. Change resulting in misreading of all nucleotides downstream - usually resulting in a truncated non functional protien
Mismatch repair
frame shift
Elastin
Hydroxylation of which amino acids are attached to Glycine to form collagen
41. Read froma fixed starting point as a continous sequenecs of bases
helicase
commaless - non - overlapping
Common amino acids in elastin
cytokeratin
42. A malfunction of mismatch repair (MUt L etc..)
Excocytosis of collagen
Euchromatin
Initial transcript without processing is known as
Hereditary non polyposis colorectal cancer
43. Prophas - metaphase - anaphase telophase
frame shift
nonsense
Heterochromatin
Order of mitosis
44. Microtubule polymerization defect resulting in lowered phagocytosis. results in recurrent pyogenic infections - partial albinism and peripheral neuropathy
Euchromatin
Chediak Higashi syndrome
Macrolides
Proofreading function in eukaryotic RNA
45. Seals
White codon is at the 3 prime end of a tRNA
DNA ligase
Prokaryotes
Guanine has a
46. Site of dteroid synthesis and detoxification of druigs and poisons (liver hepatocytes and steroid horomore adrenal cortex)
Purines
Smooth ER
Euchromatin
5FU
47. Site of secretory protiens (mucus secreting goblet cells and antibody secreting cells)
Plasma membrane composition
Type IV collagen is an important structural component of...
Rough ER
Which is the most and least abundant type of RNA
48. Lysine/hydroxylysine and combines to form collagen
step two of RNA processing
Step Three of RNA processing
Step one of RNA processing
Tropocollagen cross links between_____ to form____
49. Never go to Go divide rapidly with short G1 bone marrow - gut epithelium - skin - hair follicles
Cyclin - CDK
Labile
capped and tail transcript is called
nonsense
50. Responsible for the accuracy of amino acid selection
dyenin
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
Protein synthesis initiation
Cell cycle
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