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First Aid: Biochemistry Molecular

Subjects : health-sciences, first-aid

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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1. Nucleotide excision repair - Base Excision repair - Mismath repair
Fluoroquinolones
Which end of the tRNA is the amino acid bound to?
Single Strand DNA Repair types
Step one of RNA processing

2. More than 1 codon may code for the same amino acid
degenerate or redundant
CDKs
kinesin
tRNA gripping and going places

3. The N to C
purines
Stable (quiescent)
Protein synthesis is in which direction
kinesin

4. Read froma fixed starting point as a continous sequenecs of bases
commaless - non - overlapping
Non homologous end joining
microtubule
Protein synthesis initiation

5. 5 prime to 3 prime
Hydroxylation of which amino acids are attached to Glycine to form collagen
mRNA is syntehsized in which direction?
Permanent cells
Oubain

6. Alpha 1 antitrypisn
Initial transcript without processing is known as
Promoter mutation
Elastase is inhibited by
transition

7. G1 - S - G2 - Mitosis
Permanent cells
mRNA stop codons
Collagedn synthesis where?
Cell cycle order

8. 1) primary transcript combines with snRNPs and other proteins to form spliceosome 2) lariat shaped intermediate is generated 3) Lariat is removed and released to precisely join 2 exons
CDKs
Steps in splicing
Promoter mutation
Plasma membrane composition

9. Completed protein is released from ribosme through simple hydrolosis and dissociates
Total energy expenditure requirement for translocation
Griseofulvin
nucleotide
Termination

10. The 3 prime hydroxyl of the nascent chain is the target
Fluoroquinolones
Which end of a growing DNA strand is the target
Cholchicine
Where do introns and exons stay

11. Rampant - Massive - TIny rRNA is most common - then mRNA and then tRNA
Rough ER
Which is the most and least abundant type of RNA
Order of mitosis
RNA processing in eukaryotes occurs

12. Hn RNA
Prokaryotes
Tropocollagen cross links between_____ to form____
microtubule
Initial transcript without processing is known as

13. Site of secretory protiens (mucus secreting goblet cells and antibody secreting cells)
mRNA start codons
helicase
Rough ER
Cyclins

14. Cilia - glagella - mitotic spindle - neurons - centrioles
Protein synthesis initiation
commaless - non - overlapping
Chediak Higashi syndrome
microtubule

15. Different exons can be combined to make nique protiens in different times
Gag on pure gold
Cilia structure
Alternate splicing
transition

16. Trimming removal of n or c terminal propeptides from zymogens to generate mature proteinds
trimethoprim
Excocytosis of collagen
Post - translational modifications
Tumor Suppressors

17. Microtubule polymerization defect resulting in lowered phagocytosis. results in recurrent pyogenic infections - partial albinism and peripheral neuropathy
Molecular motor protiesn
Chediak Higashi syndrome
Mebendazole/thiabendazole
Which end of the nucleotide has the triphosphate

18. Less condensed - transciptionally active=eu truly transcobed
Cilia structure
Euchromatin
Where do introns and exons stay
The only histone not on the core

19. AD and AR- associated iwth joint dislocation - berry aneurysms - organ rupture
Associations of Ehlers Danlos
nonsense
Chediak Higashi syndrome
chromatin structure

20. Change resulting in early stop codon
nonsense
tRNA aminoacylation
GFAP
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon

21. Inhbits RNA pol II (found in death cap mushrooms)
Eukaroytes
Xeroderma pigmentosum
Which end of a growing DNA strand is the target
alpha amintin

22. ATP- AMP (2 phosphoanhydride bonds)
methionine is only encoded by
tRNA aminoacylation
DNA pol I
Promoter mutation

23. Binds 50S blocking translocation
Oubain
chromatin structure
Clindamycin
actin and myosin

24. You glyucosolate hte pro - alpha chain lysine resudens and form procollagen (triple helix of alpha chains)
nucleosid
mRNA is syntehsized in which direction?
Glycosolation
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon

25. Attachment of ubiquitin to defective proteinds to tag them for breakdown
Tumor Suppressors
GFAP
DNA ligase
Proteosomal degradation

26. Commonly results in dramatic decrease in amount of gene transcribed
Which end of the tRNA is the amino acid bound to?
Promoter mutation
DNA/RNA/Protein syntesis direction
Termination

27. VItamin C
Digoxin (cardiac glycosides)
What does the hydroxylation of proline and lysine require
pyrimadines
Euchromatin

28. Does not
polyadenylation does/does not require a template
DNA topoisomerases
Non homologous end joining
Associations of Ehlers Danlos

29. Capping on 5 prime end (7 methylguanosine) -
Step one of RNA processing
Fluoroquinolones
Glycosolation
Collagedn synthesis where?

30. Genetic code is conserved throughout evolution
Stable (quiescent)
Tumor Suppressors
universal
Eukaroytes

31. Retrograde to microtubules
dyenin
A- T
What type of collagen is most affected in Ehlers Danlos
missense mutation

32. Bind 50S blocking translocation
Macrolides
What does the hydroxylation of proline and lysine require
cytokeratin
Collagen

33. Y shaped region along DNA template where leading and lagging strands are syntehsized
Mismatch repair
Cilia structure
Replication fork
Griseofulvin

34. Elastase
What does the hydroxylation of proline and lysine require
Which end of the tRNA is the amino acid bound to?
mRNA is syntehsized in which direction?
Elastin is broken down by

35. 2 H bonds greater GC content greater melting point
Cyclin - CDK
Chediak Higashi syndrome
What ties teh nucleosome together
A- T

36. Hydroxy proline and hydroxylysine
cytokeratin
Guanine has a
Hydroxylation of which amino acids are attached to Glycine to form collagen
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon

37. AUG inAUGurates protein synthesis
mRNA start codons
pyrimadines
Cell cycle
White codon is at the 3 prime end of a tRNA

38. 1P (blocked by tetracycline)
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
transversion
Loading tRNA on to ribosome energy requirement
trimethoprim

39. Must be both activated and inactivated for cell cycle to progress
Chediak Higashi syndrome
Functional organization of the gene
commaless - non - overlapping
Cyclin - CDK

40. Contain the actual genetic information coding for protein
Exons
DNA pol III
DNA/RNA/Protein syntesis direction
intermediate filaments

41. Regulatory proteins that control cell cycle events; phase specific; activated CDKs
Termination
promoter
Cyclins
origin of replication

42. Base+ribose+phosphate linked by a phosphodiester bond
Stable (quiescent)
nucleotide
CDKs
Collagen

43. Exocytose procollagen into extracellylar sace
Covalent alterations
Aminoglycosides
Which end of the tRNA is the amino acid bound to?
Excocytosis of collagen

44. Scrutinizes aa before and after it binds to tRNA. If incorrect bond is hydrolyzed.
Total energy expenditure requirement for translocation
Example of permanent cells
Oubain
Aminoacylt - tRNA synthetase

45. Vimentin - desmin - cytockeratin - glial fibrillary acid proteins - neurofilaments
intermediate filaments
dyenin
Heterochromatin
Double Strand DNA repair

46. Site where RNA polymerase and multiple other transciption factors bind to DNA upstream from gene locus (AT rich upstream sequence with TATA and CAAT boxes)
Tumor Suppressors
promoter
Translocation
Aminoglycosides

47. ATP ase that links peripheral 9 doublets and causes bending of cilium by differential sliding of doublets
Aminoacylt - tRNA synthetase
Axonemal dyenin
Prokaryotes
Macrolides

48. RER translation of collagen alpha chains (preprocollagen) usually Gly-X-Y
Excocytosis of collagen
Enhancer
Exons
Collagedn synthesis where?

49. CUT 1 ring Cut the Py
dyenin
Free ribosomes
A- T
Pyrimidines

50. Proline - glycine
Common amino acids in elastin
nucleotide
In eukaryotes the starting amino acid is...
DNA/RNA/Protein syntesis direction

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First Aid: Biochemistry Molecular

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