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First Aid: Biochemistry Molecular

Instructions:
  • Answer 50 questions in 15 minutes.
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  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Neuroglia






2. The 3 prime hydroxyl of the nascent chain is the target






3. 4 high enrgy bonds






4. Prokaryotic only. Degrades RNA primer and fills in the gap with DNA (5 prime to 3 prime exonuclease)






5. Change resulting in misreading of all nucleotides downstream - usually resulting in a truncated non functional protien






6. 9+2 arrangement of microtubules -






7. Methyl THYmine has a meTHYl






8. Inhibits thymidylate synthase down thymine






9. Unwinds DNA template at replication fork






10. Promoter - enhancer - promoter - TATA- transcription initiation site - coding region (including exons and introns) and then the AATAAA






11. Site of secretory protiens (mucus secreting goblet cells and antibody secreting cells)






12. Epithelial cells






13. Create a nick in the helix to relieve supercoils created during replication






14. AUG inAUGurates protein synthesis






15. ATP






16. Base+ribose+phosphate linked by a phosphodiester bond






17. Commonly results in dramatic decrease in amount of gene transcribed






18. Methionine - which may be removed before translation is completed






19. Cilia - glagella - mitotic spindle - neurons - centrioles






20. Genetic bone disorder (brittle bone disease) type 1 colalgen - fractures (during birth) 2) Blue sclerae 3) hearing loss 4) dental imperfections 1:10000 may be confused with child abuse






21. 2 H bonds greater GC content greater melting point






22. Non homologous end joining






23. Condensed - transciptionally inactive HC- Highly condensed






24. Rampant - Massive - TIny rRNA is most common - then mRNA and then tRNA






25. Inhibits 50S peptidyl transferase






26. Inhibits the atpase which increases intracellular sodium which increases intracellular calcium increases cardiaccontractility






27. 3 H bonds






28. Unattached to any membrane; site of cytosolic and organeller prtoeins






29. 1) primary transcript combines with snRNPs and other proteins to form spliceosome 2) lariat shaped intermediate is generated 3) Lariat is removed and released to precisely join 2 exons






30. No proofreading function but can initiate chains. RNA poymerase II opens DNA at promoter site






31. Ribonucleotide reductase






32. Alpha 1 antitrypisn






33. Inhibit formation of the initation complex and cause misreading of mRNA






34. Stretch of DNA that alters gene expression by binding transcription factors






35. Bm - kidney - ears and eyes






36. DNA And RNA synthesized in the 5-3 direction






37. Exocytose procollagen into extracellylar sace






38. Nucleotide excision repair - Base Excision repair - Mismath repair






39. Less condensed - transciptionally active=eu truly transcobed






40. Specific endonucleases release the oligonucleotide containing damaged bases. DNA polymerase and logase fill and resealt eh gap






41. Even 40S 60S =80S






42. Asymmetric fluid bilayer - contains - cholesterol - phospholipids - sphingoplipids - glycolipids - and protiends






43. Bind 50S blocking translocation






44. A site - incoming aminoacyl tRNA - Psite accomodates growing Peptide - E site holds EmplytRNA as it exits






45. Three amino acids necessary for purine synthesis= glutamine - aspartate and glycine






46. Remain in G0 regenerate from stem cells






47. VItamin C






48. Seals






49. Prevents stranges from reannealing






50. Mutation in nucleotide excision repair Dry skin with melanoma and other cancers