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First Aid: Biochemistry Molecular

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Stretch of DNA that alters gene expression by binding transcription factors






2. A site - incoming aminoacyl tRNA - Psite accomodates growing Peptide - E site holds EmplytRNA as it exits






3. Prokaryotic only. Elongates leading strand by adding deoxynucleotides to the 3prime end. Elongates laggin strand. 3 prime to 5 prime exonuclease activity






4. Completed protein is released from ribosme through simple hydrolosis and dissociates






5. Genetic bone disorder (brittle bone disease) type 1 colalgen - fractures (during birth) 2) Blue sclerae 3) hearing loss 4) dental imperfections 1:10000 may be confused with child abuse






6. 3 sodium out for 2 potassium in (nout - kin)takes 1 atp and the machine is phosphorylated during the machine cycle






7. Inhbits RNA pol II (found in death cap mushrooms)






8. Xlinked recessive IV collagen bm - kidney - ear and eye -- nephritis and defness ocular disturbances






9. CCA AT 3 PRIME END






10. 75-90 nucleotides - 2ary structure cloverleaf form anticodon end is opposite 3 prime aminoacyl end






11. Checkpoints control transition between phases of cell cycle. regulated by cyclins - CDKs and tumor suppressors. Mitosis (shortest phse)






12. The 3 prime end






13. Odd 30S plus 50 S=70S






14. The 3 prime hydroxyl of the nascent chain is the target






15. Has enough energy to created the peptide bond






16. Bind 30S subunit preventing attachment of aminoacyl - tRNA






17. Epithelial cells






18. Commonly results in dramatic decrease in amount of gene transcribed






19. Less condensed - transciptionally active=eu truly transcobed






20. Activated by GTP hydrolosis initiation factors help assembel the 40 S ribosomal subunites with the initiatior tRNA and are released whent he mRNA and the ribosomal subunit assemple with the complex






21. DNA And RNA synthesized in the 5-3 direction






22. Must be both activated and inactivated for cell cycle to progress






23. Enter G1 from G0 when stimulated Hepatocytes/lymphocytes






24. Anti cancer - act on microtubules






25. Hydroxy proline and hydroxylysine






26. Neurons






27. More than 1 codon may code for the same amino acid






28. Particular sequnece in genomre where DNA replication begins. May be single (prokaryotes) or multiple (eukaryotes)






29. Site where RNA polymerase and multiple other transciption factors bind to DNA upstream from gene locus (AT rich upstream sequence with TATA and CAAT boxes)






30. Exocytose procollagen into extracellylar sace






31. Greater melting temperature lower fluidity






32. Read froma fixed starting point as a continous sequenecs of bases






33. Base+ribose+phosphate linked by a phosphodiester bond






34. Y shaped region along DNA template where leading and lagging strands are syntehsized






35. Cleave terminal regions of procollagen to transform into insoluable tropocolagen






36. Never go to Go divide rapidly with short G1 bone marrow - gut epithelium - skin - hair follicles






37. Unmethylated - newly synthesized string is recognized - mismatched nucleotides are removed and the gap is filled and resealed






38. Trimming removal of n or c terminal propeptides from zymogens to generate mature proteinds






39. Even 40S 60S =80S






40. Hn RNA






41. Each codon specifies only 1 amino acid






42. Bind 50S blocking translocation






43. Does not






44. Scrutinizes aa before and after it binds to tRNA. If incorrect bond is hydrolyzed.






45. Inhibits ribonucleotide reductase






46. Uracil






47. Tansport cellular cargo toward opposite ends of microtubule tracks






48. Aminoacyl - tRNA binds to A site 2) peptidyltransferase catalyzes peptide bond formation transfers growing polypeptie to amino acid in A site 3) ribosome advances 3 nucleotides toward the 3 prime end of RNA moving peptiydyl RNA to P site






49. Negatively charged DNA loops twice around histone octamers create a nucloesome bead.






50. Ribonucleotide reductase