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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Capping on 5 prime end (7 methylguanosine) -
Step one of RNA processing
Deamination of cytosine makes
Initial transcript without processing is known as
DNA topoisomerases
2. Microvilli - muscle contraction - cytokinesis - adhering juntions
purines
tRNA Structure
Prokaryotes
actin and myosin
3. Inhibits ribonucleotide reductase
Which end of a growing DNA strand is the target
hydroxyurea
Deamination of cytosine makes
transversion
4. Same aa often base change in 3rd position of codon
silent mutation
DNA ligase
Example of permanent cells
Steps in splicing
5. Made from orogate precuror with PRPP added later
Heterochromatin
Nucleotide excision repair
Paclitaxil
pyrimadines
6. Unmethylated - newly synthesized string is recognized - mismatched nucleotides are removed and the gap is filled and resealed
tRNA
Double Strand DNA repair
6MP
Mismatch repair
7. Cyclin depndent kinases; consituative and inactive
Initial transcript without processing is known as
Stable (quiescent)
Osteogenesis Imperfecta
CDKs
8. Microtubule polymerization defect resulting in lowered phagocytosis. results in recurrent pyogenic infections - partial albinism and peripheral neuropathy
Aminoglycosides
Primase
Clindamycin
Chediak Higashi syndrome
9. Connective tissue
Proofreading function in eukaryotic RNA
Immunohistochemical stains vimentin
CDKs
step two of RNA processing
10. Uracil
Step Three of RNA processing
DNA topoisomerases
Deamination of cytosine makes
Which end of the tRNA is the amino acid bound to?
11. 1P (blocked by tetracycline)
Loading tRNA on to ribosome energy requirement
Purines
Which end of a growing DNA strand is the target
What ties teh nucleosome together
12. CCA AT 3 PRIME END
Clindamycin
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
White codon is at the 3 prime end of a tRNA
Going APE
13. ATP
mRNA is syntehsized in which direction?
tRNA activation
histone octamer names
Nucleotide excision repair
14. Inhibits dihydrofolate reductase down thymine
Clindamycin
actin and myosin
Methotrexate
Eukaroytes
15. Tansport cellular cargo toward opposite ends of microtubule tracks
Exons
hydroxyurea
Molecular motor protiesn
Outside the cell what processing must be done in procolalgen
16. Prevents stranges from reannealing
Base excision repair
single stranded binding proteinds
Cholchicine
DNA topoisomerases
17. 5 prime to 3 prime
Neurofilaments
mRNA is syntehsized in which direction?
helicase
What does the hydroxylation of proline and lysine require
18. Codes for formyl methionine (f - Met)
AUG codes For what in prokaryotes
Kartageners syndrome
Ehlers Danlos
Step one of RNA processing
19. Type III
Osteogenesis Imperfecta
Labile
step two of RNA processing
What type of collagen is most affected in Ehlers Danlos
20. 1) primary transcript combines with snRNPs and other proteins to form spliceosome 2) lariat shaped intermediate is generated 3) Lariat is removed and released to precisely join 2 exons
Smooth ER
Steps in splicing
Alternate splicing
RNA polymerases in eukaryotes
21. Does not
Axonemal dyenin
5FU
Protein synthesis initiation
polyadenylation does/does not require a template
22. Remain in G0 regenerate from stem cells
Permanent cells
Hereditary non polyposis colorectal cancer
The only histone not on the core
Translocation
23. VItamin C
Purines
What does the hydroxylation of proline and lysine require
Cholchicine
polyadenylation does/does not require a template
24. A site - incoming aminoacyl tRNA - Psite accomodates growing Peptide - E site holds EmplytRNA as it exits
helicase
Tropocollagen cross links between_____ to form____
Going APE
Chloramphenicol
25. Inhibits thymidylate synthase down thymine
Single Strand DNA Repair types
5FU
cytokeratin
Molecular motor protiesn
26. Made from IMP precursor
purines
Elastin is broken down by
mRNA is syntehsized in which direction?
Initial transcript without processing is known as
27. MRNA
Enhancers and silencer may be located_____
Excocytosis of collagen
capped and tail transcript is called
Proofreading function in eukaryotic RNA
28. 75-90 nucleotides - 2ary structure cloverleaf form anticodon end is opposite 3 prime aminoacyl end
Primase
A- T
DNA/RNA/Protein syntesis direction
tRNA Structure
29. Asymmetric fluid bilayer - contains - cholesterol - phospholipids - sphingoplipids - glycolipids - and protiends
Elongation
Plasma membrane composition
Cell cycle order
The only histone not on the core
30. Anti cancer - act on microtubules
Elongation
Vincristine/Vinblastine
What ties teh nucleosome together
Molecular motor protiesn
31. Alpha 1 antitrypisn
Elastase is inhibited by
Immunohistochemical stains vimentin
Cell cycle order
Xeroderma pigmentosum
32. Seals
Base excision repair
Type IV collagen is an important structural component of...
DNA ligase
Hydroxylation of which amino acids are attached to Glycine to form collagen
33. Inhibits 50S peptidyl transferase
Digoxin (cardiac glycosides)
Eukaroytes
Axonemal dyenin
Chloramphenicol
34. 3 H bonds
Fluoroquinolones
silent mutation
C- G bond
universal
35. In the nucleus after transcitpion and only processed RNA is transporte out of the nucleus
RNA processing in eukaryotes occurs
desmin
cytokeratin
Smooth ER
36. Stretch of DNA that alters gene expression by binding transcription factors
Enhancer
transition
C- G bond
Replication fork
37. Promoter - enhancer - promoter - TATA- transcription initiation site - coding region (including exons and introns) and then the AATAAA
nucleotide
Associations of Ehlers Danlos
Functional organization of the gene
tRNA activation
38. Site of dteroid synthesis and detoxification of druigs and poisons (liver hepatocytes and steroid horomore adrenal cortex)
Smooth ER
Step one of RNA processing
unambiguous
What type of collagen is most affected in Ehlers Danlos
39. Anterograde to microtubule
Which end of the tRNA is the amino acid bound to?
kinesin
universal
What does the hydroxylation of proline and lysine require
40. Makes an RNA primer on which DNA polymerase II can initiate replication
DNA topoisomerases
Primase
capped and tail transcript is called
RNA processing in eukaryotes occurs
41. CUT 1 ring Cut the Py
Pyrimidines
Oubain
trimethoprim
single stranded binding proteinds
42. Proline - glycine
Collagedn synthesis where?
5FU
Common amino acids in elastin
Kartageners syndrome
43. Aminoacyl - tRNA binds to A site 2) peptidyltransferase catalyzes peptide bond formation transfers growing polypeptie to amino acid in A site 3) ribosome advances 3 nucleotides toward the 3 prime end of RNA moving peptiydyl RNA to P site
Elongation
Loading tRNA on to ribosome energy requirement
Functional organization of the gene
Which is the most and least abundant type of RNA
44. Intervening noncoding segments of DNA
Introns
Silencer
Kartageners syndrome
Termination
45. Blocks denovo purine synthesis
A- T
intermediate filaments
Methotrexate
6MP
46. Enter G1 from G0 when stimulated Hepatocytes/lymphocytes
Proteosomal degradation
nonsense
chromatin structure
Stable (quiescent)
47. Site where negative regulators bind
Elastin
Silencer
actin and myosin
Common amino acids in elastin
48. Negatively charged DNA loops twice around histone octamers create a nucloesome bead.
step two of RNA processing
chromatin structure
Nucleotide excision repair
Macrolides
49. Commonly results in dramatic decrease in amount of gene transcribed
What ties teh nucleosome together
Cell cycle order
Ehlers Danlos
Promoter mutation
50. Base+ribose+phosphate linked by a phosphodiester bond
nucleotide
alpha amintin
Methotrexate
Step Three of RNA processing