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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Negatively charged DNA loops twice around histone octamers create a nucloesome bead.
Which end of the tRNA is the amino acid bound to?
Loading tRNA on to ribosome energy requirement
chromatin structure
Aminoacylt - tRNA synthetase
2. 3 H bonds
Step Three of RNA processing
Post - translational modifications
C- G bond
Collagen
3. Intervening noncoding segments of DNA
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
Elastin is broken down by
commaless - non - overlapping
Introns
4. Inhibits the atpase which increases intracellular sodium which increases intracellular calcium increases cardiaccontractility
transition
5FU
Step one of RNA processing
Digoxin (cardiac glycosides)
5. The 5prime end (energy for the bond)
Elastase is inhibited by
nucleosid
What ties teh nucleosome together
Which end of the nucleotide has the triphosphate
6. No proofreading function but can initiate chains. RNA poymerase II opens DNA at promoter site
Higher the cholesterol or long saturated fatty acid content
Eukaroytes
Proofreading function in eukaryotic RNA
Collagedn synthesis where?
7. A site - incoming aminoacyl tRNA - Psite accomodates growing Peptide - E site holds EmplytRNA as it exits
What type of collagen is most affected in Ehlers Danlos
Going APE
Osteogenesis Imperfecta
Prokaryote RNA pol
8. Cyclin depndent kinases; consituative and inactive
Thymine has a
CDKs
Cyclins
Primase
9. Condensed - transciptionally inactive HC- Highly condensed
chromatin structure
Alports syndrome
Elastin
Heterochromatin
10. The N to C
Methotrexate
chromatin structure
Protein synthesis is in which direction
Chloramphenicol
11. Site where RNA polymerase and multiple other transciption factors bind to DNA upstream from gene locus (AT rich upstream sequence with TATA and CAAT boxes)
Glycosolation
Primase
promoter
Deamination of cytosine makes
12. Specific endonucleases release the oligonucleotide containing damaged bases. DNA polymerase and logase fill and resealt eh gap
Initial transcript without processing is known as
Osteogenesis Imperfecta
Pyrimidines
Nucleotide excision repair
13. Close to - far from or even within (in an intron) the gene whose expression it regulates
Thymine has a
Elastin
Enhancers and silencer may be located_____
Which end of the nucleotide has the triphosphate
14. The 3 prime end
AUG codes For what in prokaryotes
Which end of the tRNA is the amino acid bound to?
Post - translational modifications
Elastin
15. Particular sequnece in genomre where DNA replication begins. May be single (prokaryotes) or multiple (eukaryotes)
Rough ER
Associations of Ehlers Danlos
Exons
origin of replication
16. Microtubule polymerization defect resulting in lowered phagocytosis. results in recurrent pyogenic infections - partial albinism and peripheral neuropathy
DNA topoisomerases
Termination
Macrolides
Chediak Higashi syndrome
17. Same aa often base change in 3rd position of codon
nucleotide
DNA pol III
silent mutation
Chediak Higashi syndrome
18. Be So Totatally Cool Read Books (bOne - CarTWOlage - Threeticular - Type IV under the floor)
Collagen
Nucleotide excision repair
polyadenylation does/does not require a template
C- G bond
19. Base + ribose
promoter
mRNA stop codons
actin and myosin
nucleosid
20. Hn RNA
Rough ER
Initial transcript without processing is known as
Deamination of cytosine makes
In eukaryotes the starting amino acid is...
21. Scrutinizes aa before and after it binds to tRNA. If incorrect bond is hydrolyzed.
Covalent alterations
single stranded binding proteinds
Double Strand DNA repair
Aminoacylt - tRNA synthetase
22. More than 1 codon may code for the same amino acid
degenerate or redundant
kinesin
Neurofilaments
step two of RNA processing
23. Immotile cilia due to a dyenin arm defect. Results in male nad female inferticility (sperm immotile) - bronchiectasis - and recurrent sinusisits - associated with situs inversus
Pyrimidines
Kartageners syndrome
What ties teh nucleosome together
Silencer
24. Splicing out of introns
Chloramphenicol
Outside the cell what processing must be done in procolalgen
Step Three of RNA processing
Xeroderma pigmentosum
25. 1) primary transcript combines with snRNPs and other proteins to form spliceosome 2) lariat shaped intermediate is generated 3) Lariat is removed and released to precisely join 2 exons
Elastin
Steps in splicing
kinesin
Replication fork
26. Odd 30S plus 50 S=70S
tRNA activation
Hereditary non polyposis colorectal cancer
Prokaryotes
transition
27. Even 40S 60S =80S
5FU
tRNA Structure
Macrolides
Eukaroytes
28. Checkpoints control transition between phases of cell cycle. regulated by cyclins - CDKs and tumor suppressors. Mitosis (shortest phse)
Post - translational modifications
Steps in splicing
5FU
Cell cycle
29. 1 RNA polymerase (multisubunite complex) makes all 3 kinds of RNA
Prokaryote RNA pol
Neurofilaments
Elastin
GFAP
30. Stretch of DNA that alters gene expression by binding transcription factors
Which end of the tRNA is the amino acid bound to?
Enhancer
Proteosomal degradation
missense mutation
31. Phosphorylation - glycosloation - hyderoxylation
5FU
silent mutation
Protein synthesis is in which direction
Covalent alterations
32. Poly adenylation
A- T
Cell cycle order
step two of RNA processing
Nucleotide excision repair
33. H1 string
Cholchicine
What ties teh nucleosome together
Axonemal dyenin
Which end of the tRNA is the amino acid bound to?
34. Three amino acids necessary for purine synthesis= glutamine - aspartate and glycine
frame shift
helicase
degenerate or redundant
Gag on pure gold
35. MRNA
Ehlers Danlos
capped and tail transcript is called
RNA processing in eukaryotes occurs
Free ribosomes
36. Inhibit DNA gyrase (specific prokaryotic topoisomerase)
Exons
Fluoroquinolones
Elastase is inhibited by
Mebendazole/thiabendazole
37. P53 and RB normally inhibit g1 to S progression
Labile
AUG codes For what in prokaryotes
Tumor Suppressors
dyenin
38. Nucleotide excision repair - Base Excision repair - Mismath repair
Single Strand DNA Repair types
DNA pol III
promoter
the tRNA- amino acid bond
39. Makes an RNA primer on which DNA polymerase II can initiate replication
Cyclins
Primase
Aminoacylt - tRNA synthetase
unambiguous
40. Antifungal - act on microtubules
Silencer
Hereditary non polyposis colorectal cancer
nucleosid
Griseofulvin
41. Never go to Go divide rapidly with short G1 bone marrow - gut epithelium - skin - hair follicles
Mismatch repair
Labile
Enhancers and silencer may be located_____
Immunohistochemical stains vimentin
42. Strethchy protein within lungs - large artiers - elastic liaments - vocal cords - ligamenta flava)
Elongation
Which end of the nucleotide has the triphosphate
Guanine has a
Elastin
43. Promoter - enhancer - promoter - TATA- transcription initiation site - coding region (including exons and introns) and then the AATAAA
Order of mitosis
degenerate or redundant
What does the hydroxylation of proline and lysine require
Functional organization of the gene
44. CUT 1 ring Cut the Py
Outside the cell what processing must be done in procolalgen
Cell cycle
Pyrimidines
DNA pol III
45. ATP
hydroxyurea
Associations of Ehlers Danlos
nucleotide
tRNA activation
46. Create a nick in the helix to relieve supercoils created during replication
DNA topoisomerases
Replication fork
Proofreading function in eukaryotic RNA
silent mutation
47. Capping on 5 prime end (7 methylguanosine) -
Step one of RNA processing
Paclitaxil
pyrimadines
Functional organization of the gene
48. 3 sodium out for 2 potassium in (nout - kin)takes 1 atp and the machine is phosphorylated during the machine cycle
Aminoacylt - tRNA synthetase
Euchromatin
Sodium K ATPase
tRNA activation
49. Xlinked recessive IV collagen bm - kidney - ear and eye -- nephritis and defness ocular disturbances
Alports syndrome
CDKs
Base excision repair
tRNA Structure
50. 2 H bonds greater GC content greater melting point
tRNA
Methotrexate
A- T
Glycosolation