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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Inhibits thymidylate synthase down thymine
Going APE
5FU
hydroxyurea
the tRNA- amino acid bond
2. Inhbits RNA pol II (found in death cap mushrooms)
What type of collagen is most affected in Ehlers Danlos
Chloramphenicol
alpha amintin
Tropocollagen cross links between_____ to form____
3. Elastase
degenerate or redundant
Fluoroquinolones
Elastin is broken down by
Replication fork
4. Commonly results in dramatic decrease in amount of gene transcribed
Promoter mutation
Chloramphenicol
Cilia structure
A- T
5. Made from IMP precursor
tRNA activation
Elastase is inhibited by
Alports syndrome
purines
6. Ribonucleotide reductase
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
actin and myosin
Primase
Fluoroquinolones
7. Does not
cytokeratin
Prokaryote RNA pol
polyadenylation does/does not require a template
microtubule
8. Cleave terminal regions of procollagen to transform into insoluable tropocolagen
Elastase is inhibited by
Outside the cell what processing must be done in procolalgen
Tumor Suppressors
histone octamer names
9. Close to - far from or even within (in an intron) the gene whose expression it regulates
tRNA Structure
degenerate or redundant
Aminoglycosides
Enhancers and silencer may be located_____
10. AUG inAUGurates protein synthesis
origin of replication
Gag on pure gold
mRNA start codons
frame shift
11. Makes an RNA primer on which DNA polymerase II can initiate replication
Total energy expenditure requirement for translocation
Primase
trimethoprim
Clindamycin
12. 4 high enrgy bonds
tRNA aminoacylation
Total energy expenditure requirement for translocation
Proofreading function in eukaryotic RNA
Macrolides
13. Introns stay In the nucleus whereas EXons EXit and are EXpressed
Cyclins
Prokaryote RNA pol
Cyclin - CDK
Where do introns and exons stay
14. Lysine/hydroxylysine and combines to form collagen
Which is the most and least abundant type of RNA
Collagedn synthesis where?
Guanine has a
Tropocollagen cross links between_____ to form____
15. Specific glycosylases recognize and remove damaged bases - AP endonuclease cuts DNA at pyrimidne site - empty sugar is removed and the gap is filled and resealed
Base excision repair
Cilia structure
Enhancers and silencer may be located_____
Elastin is broken down by
16. Site of secretory protiens (mucus secreting goblet cells and antibody secreting cells)
Exons
Rough ER
Chediak Higashi syndrome
Deamination of cytosine makes
17. Splicing out of introns
Elastin
Step Three of RNA processing
Oubain
Which end of the nucleotide has the triphosphate
18. Anti breast cancer - acts on mts
Tropocollagen cross links between_____ to form____
Collagen
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
Paclitaxil
19. Bind 30S subunit preventing attachment of aminoacyl - tRNA
Tetracyclines
polyadenylation does/does not require a template
Introns
Steps in splicing
20. HS1 - HSB - H2 - H4
Elastin
Elastin is broken down by
histone octamer names
tRNA activation
21. Intervening noncoding segments of DNA
Termination
Introns
the tRNA- amino acid bond
helicase
22. Bm - kidney - ears and eyes
Type IV collagen is an important structural component of...
Translocation
Associations of Ehlers Danlos
Cholchicine
23. Microvilli - muscle contraction - cytokinesis - adhering juntions
White codon is at the 3 prime end of a tRNA
Alternate splicing
Single Strand DNA Repair types
actin and myosin
24. Site of dteroid synthesis and detoxification of druigs and poisons (liver hepatocytes and steroid horomore adrenal cortex)
RNA processing in eukaryotes occurs
Smooth ER
Which is the most and least abundant type of RNA
tRNA
25. Particular sequnece in genomre where DNA replication begins. May be single (prokaryotes) or multiple (eukaryotes)
origin of replication
Tetracyclines
chromatin structure
RNA processing in eukaryotes occurs
26. Change resulting in early stop codon
nonsense
C- G bond
Cilia structure
transition
27. Create a nick in the helix to relieve supercoils created during replication
DNA topoisomerases
Exons
Step one of RNA processing
Pyrimidines
28. Hn RNA
Initial transcript without processing is known as
What type of collagen is most affected in Ehlers Danlos
Permanent cells
Primase
29. Prophas - metaphase - anaphase telophase
universal
GFAP
Elastin is broken down by
Order of mitosis
30. Prevents stranges from reannealing
single stranded binding proteinds
Which end of the tRNA is the amino acid bound to?
5FU
Rough ER
31. A malfunction of mismatch repair (MUt L etc..)
Cell cycle
Macrolides
Tropocollagen cross links between_____ to form____
Hereditary non polyposis colorectal cancer
32. Proline - glycine
Smooth ER
Common amino acids in elastin
transition
Hereditary non polyposis colorectal cancer
33. The 3 prime hydroxyl of the nascent chain is the target
Which end of a growing DNA strand is the target
Initial transcript without processing is known as
hydroxyurea
cytokeratin
34. Y shaped region along DNA template where leading and lagging strands are syntehsized
Replication fork
capped and tail transcript is called
Ehlers Danlos
commaless - non - overlapping
35. Binds 50S blocking translocation
Clindamycin
microtubule
Enhancers and silencer may be located_____
unambiguous
36. Accurate base pairing is required only in the first 2 nucleotide positions of an mRNA so codons differing ht e3rd wobble psoition may code for the same tRNA/amino acid code
tRNA
helicase
tRNA activation
White codon is at the 3 prime end of a tRNA
37. Type III
Immunohistochemical stains vimentin
Primase
What type of collagen is most affected in Ehlers Danlos
Prokaryotes
38. 2 H bonds greater GC content greater melting point
Aminoglycosides
Sodium K ATPase
A- T
5FU
39. Cylindrical structure composed of helical array of plymerized dimers of alpha and beta tubulin - flagella - cilia - mitotic spindle - grows slowly collapses quickly
What does the hydroxylation of proline and lysine require
microtubule
nonsense
DNA ligase
40. CCA AT 3 PRIME END
Tumor Suppressors
origin of replication
Proofreading function in eukaryotic RNA
White codon is at the 3 prime end of a tRNA
41. G1 - S - G2 - Mitosis
Fluoroquinolones
Cell cycle order
universal
Cyclin - CDK
42. AD and AR- associated iwth joint dislocation - berry aneurysms - organ rupture
Example of permanent cells
Vincristine/Vinblastine
Axonemal dyenin
Associations of Ehlers Danlos
43. Greater melting temperature lower fluidity
Thymine has a
tRNA aminoacylation
Higher the cholesterol or long saturated fatty acid content
Fluoroquinolones
44. Inhibits ribonucleotide reductase
Kartageners syndrome
Cell cycle
Exons
hydroxyurea
45. Faulty collagen synthesis causing 1) hyperextensible skin 2) tendency to bleed 3) hypermobile joints
Ehlers Danlos
Rough ER
cytokeratin
Vincristine/Vinblastine
46. Ketone
Enhancers and silencer may be located_____
Guanine has a
A- T
Chediak Higashi syndrome
47. Inhibits 50S peptidyl transferase
Chloramphenicol
origin of replication
nonsense
step two of RNA processing
48. Genetic bone disorder (brittle bone disease) type 1 colalgen - fractures (during birth) 2) Blue sclerae 3) hearing loss 4) dental imperfections 1:10000 may be confused with child abuse
Common amino acids in elastin
cytokeratin
Osteogenesis Imperfecta
C- G bond
49. Inhibit DNA gyrase (specific prokaryotic topoisomerase)
Collagen
Base excision repair
Fluoroquinolones
histone octamer names
50. CUT 1 ring Cut the Py
promoter
Mebendazole/thiabendazole
Euchromatin
Pyrimidines