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First Aid: Biochemistry Molecular

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Commonly results in dramatic decrease in amount of gene transcribed






2. Anti breast cancer - acts on mts






3. Anti cancer - act on microtubules






4. Antigout - acts on mts






5. Nucleotide excision repair - Base Excision repair - Mismath repair






6. AD and AR- associated iwth joint dislocation - berry aneurysms - organ rupture






7. Trimming removal of n or c terminal propeptides from zymogens to generate mature proteinds






8. Stretch of DNA that alters gene expression by binding transcription factors






9. Genetic bone disorder (brittle bone disease) type 1 colalgen - fractures (during birth) 2) Blue sclerae 3) hearing loss 4) dental imperfections 1:10000 may be confused with child abuse






10. Prokaryotic only. Degrades RNA primer and fills in the gap with DNA (5 prime to 3 prime exonuclease)






11. Codes for formyl methionine (f - Met)






12. Tansport cellular cargo toward opposite ends of microtubule tracks






13. Capping on 5 prime end (7 methylguanosine) -






14. H1






15. Cylindrical structure composed of helical array of plymerized dimers of alpha and beta tubulin - flagella - cilia - mitotic spindle - grows slowly collapses quickly






16. HS1 - HSB - H2 - H4






17. Greater melting temperature lower fluidity






18. Vimentin - desmin - cytockeratin - glial fibrillary acid proteins - neurofilaments






19. Strethchy protein within lungs - large artiers - elastic liaments - vocal cords - ligamenta flava)






20. Unmethylated - newly synthesized string is recognized - mismatched nucleotides are removed and the gap is filled and resealed






21. 5 prime to 3 prime






22. Methionine - which may be removed before translation is completed






23. Site where negative regulators bind






24. CUT 1 ring Cut the Py






25. Responsible for the accuracy of amino acid selection






26. Proline - glycine






27. Retrograde to microtubules






28. No proofreading function but can initiate chains. RNA poymerase II opens DNA at promoter site






29. Inhibits dihydrofolate reductase down thymine






30. 75-90 nucleotides - 2ary structure cloverleaf form anticodon end is opposite 3 prime aminoacyl end






31. Exocytose procollagen into extracellylar sace






32. Different exons can be combined to make nique protiens in different times






33. Change resulting in early stop codon






34. Unwinds DNA template at replication fork






35. Site of secretory protiens (mucus secreting goblet cells and antibody secreting cells)






36. A malfunction of mismatch repair (MUt L etc..)






37. DNA And RNA synthesized in the 5-3 direction






38. Negatively charged DNA loops twice around histone octamers create a nucloesome bead.






39. Three amino acids necessary for purine synthesis= glutamine - aspartate and glycine






40. Phosphorylation - glycosloation - hyderoxylation






41. Inhibits by binding to the potassium side






42. Inhibits bacterials dihydrofolate reducatese down thymine






43. A site - incoming aminoacyl tRNA - Psite accomodates growing Peptide - E site holds EmplytRNA as it exits






44. Cleave terminal regions of procollagen to transform into insoluable tropocolagen






45. Remain in G0 regenerate from stem cells






46. Microtubule polymerization defect resulting in lowered phagocytosis. results in recurrent pyogenic infections - partial albinism and peripheral neuropathy






47. Same aa often base change in 3rd position of codon






48. 1P blocked by chloramphenicaol and macrolide






49. CCA AT 3 PRIME END






50. Microvilli - muscle contraction - cytokinesis - adhering juntions