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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. 4 high enrgy bonds
microtubule
mRNA is syntehsized in which direction?
Total energy expenditure requirement for translocation
desmin
2. Specific endonucleases release the oligonucleotide containing damaged bases. DNA polymerase and logase fill and resealt eh gap
Elongation
Proofreading function in eukaryotic RNA
Methotrexate
Nucleotide excision repair
3. Trimming removal of n or c terminal propeptides from zymogens to generate mature proteinds
DNA topoisomerases
trimethoprim
nonsense
Post - translational modifications
4. Cyclin depndent kinases; consituative and inactive
CDKs
AUG codes For what in prokaryotes
Glycosolation
Methotrexate
5. CCA AT 3 PRIME END
White codon is at the 3 prime end of a tRNA
Free ribosomes
mRNA stop codons
Oubain
6. Y shaped region along DNA template where leading and lagging strands are syntehsized
Heterochromatin
Replication fork
alpha amintin
Labile
7. Made from IMP precursor
Which is the most and least abundant type of RNA
purines
Proofreading function in eukaryotic RNA
Associations of Ehlers Danlos
8. Brings together 2 ends of DNA fragments no requirement for homology
6MP
Type IV collagen is an important structural component of...
Non homologous end joining
Tropocollagen cross links between_____ to form____
9. Exocytose procollagen into extracellylar sace
Chediak Higashi syndrome
Excocytosis of collagen
Double Strand DNA repair
Tetracyclines
10. Inhibit DNA gyrase (specific prokaryotic topoisomerase)
Fluoroquinolones
histone octamer names
Single Strand DNA Repair types
Aminoacylt - tRNA synthetase
11. Phosphorylation - glycosloation - hyderoxylation
trimethoprim
Covalent alterations
Proofreading function in eukaryotic RNA
Protein synthesis initiation
12. Commonly results in dramatic decrease in amount of gene transcribed
Silencer
Enhancer
tRNA Structure
Promoter mutation
13. One codon AUG
Base excision repair
CDKs
Fluoroquinolones
methionine is only encoded by
14. Codes for formyl methionine (f - Met)
Labile
AUG codes For what in prokaryotes
Enhancer
Euchromatin
15. Three amino acids necessary for purine synthesis= glutamine - aspartate and glycine
Covalent alterations
Gag on pure gold
purines
capped and tail transcript is called
16. Neurons
Neurofilaments
tRNA
tRNA gripping and going places
Digoxin (cardiac glycosides)
17. Change resulting in misreading of all nucleotides downstream - usually resulting in a truncated non functional protien
frame shift
Heterochromatin
trimethoprim
the tRNA- amino acid bond
18. No proofreading function but can initiate chains. RNA poymerase II opens DNA at promoter site
Proofreading function in eukaryotic RNA
Which end of the tRNA is the amino acid bound to?
Cell cycle order
Collagen
19. Inhibits dihydrofolate reductase down thymine
Which end of the nucleotide has the triphosphate
alpha amintin
Aminoglycosides
Methotrexate
20. Genetic code is conserved throughout evolution
universal
Cilia structure
Macrolides
Exons
21. Substituting a purine for a pyrimdine or vice versa
Introns
transversion
Pyrimidines
universal
22. Proline - glycine
Mismatch repair
The only histone not on the core
Common amino acids in elastin
Heterochromatin
23. 2 H bonds greater GC content greater melting point
In eukaryotes the starting amino acid is...
A- T
Functional organization of the gene
Aminoacylt - tRNA synthetase
24. Inhibit formation of the initation complex and cause misreading of mRNA
Enhancer
Immunohistochemical stains vimentin
degenerate or redundant
Aminoglycosides
25. ATP ase that links peripheral 9 doublets and causes bending of cilium by differential sliding of doublets
Total energy expenditure requirement for translocation
Digoxin (cardiac glycosides)
histone octamer names
Axonemal dyenin
26. Site where RNA polymerase and multiple other transciption factors bind to DNA upstream from gene locus (AT rich upstream sequence with TATA and CAAT boxes)
Protein synthesis initiation
Translocation
promoter
GFAP
27. H1 string
What ties teh nucleosome together
Molecular motor protiesn
Tropocollagen cross links between_____ to form____
helicase
28. Prokaryotic only. Degrades RNA primer and fills in the gap with DNA (5 prime to 3 prime exonuclease)
step two of RNA processing
6MP
Free ribosomes
DNA pol I
29. Site of dteroid synthesis and detoxification of druigs and poisons (liver hepatocytes and steroid horomore adrenal cortex)
Aminoacylt - tRNA synthetase
Smooth ER
commaless - non - overlapping
Aminoglycosides
30. UGA - UAG - UAA
Functional organization of the gene
Post - translational modifications
mRNA stop codons
tRNA
31. Inhibits thymidylate synthase down thymine
alpha amintin
5FU
Excocytosis of collagen
Euchromatin
32. Completed protein is released from ribosme through simple hydrolosis and dissociates
Nucleotide excision repair
Primase
Which is the most and least abundant type of RNA
Termination
33. AUG inAUGurates protein synthesis
mRNA start codons
Mismatch repair
Steps in splicing
Which end of the nucleotide has the triphosphate
34. AD and AR- associated iwth joint dislocation - berry aneurysms - organ rupture
histone octamer names
Loading tRNA on to ribosome energy requirement
Associations of Ehlers Danlos
What ties teh nucleosome together
35. Inhibits the atpase which increases intracellular sodium which increases intracellular calcium increases cardiaccontractility
Total energy expenditure requirement for translocation
Digoxin (cardiac glycosides)
Methotrexate
Tetracyclines
36. Attachment of ubiquitin to defective proteinds to tag them for breakdown
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
Immunohistochemical stains vimentin
Kartageners syndrome
Proteosomal degradation
37. Microvilli - muscle contraction - cytokinesis - adhering juntions
actin and myosin
desmin
Ehlers Danlos
Step Three of RNA processing
38. Vimentin - desmin - cytockeratin - glial fibrillary acid proteins - neurofilaments
Paclitaxil
Covalent alterations
Hydroxylation of which amino acids are attached to Glycine to form collagen
intermediate filaments
39. 75-90 nucleotides - 2ary structure cloverleaf form anticodon end is opposite 3 prime aminoacyl end
nonsense
pyrimadines
tRNA Structure
frame shift
40. Intervening noncoding segments of DNA
Osteogenesis Imperfecta
Elastin
Cholchicine
Introns
41. Blocks denovo purine synthesis
Prokaryotes
Example of permanent cells
6MP
purines
42. Enter G1 from G0 when stimulated Hepatocytes/lymphocytes
Collagedn synthesis where?
Stable (quiescent)
Cell cycle order
Chloramphenicol
43. Faulty collagen synthesis causing 1) hyperextensible skin 2) tendency to bleed 3) hypermobile joints
tRNA gripping and going places
C- G bond
Ehlers Danlos
tRNA Structure
44. Hydroxy proline and hydroxylysine
Cilia structure
Hydroxylation of which amino acids are attached to Glycine to form collagen
Protein synthesis initiation
Chloramphenicol
45. Create a nick in the helix to relieve supercoils created during replication
Step Three of RNA processing
5FU
Enhancers and silencer may be located_____
DNA topoisomerases
46. CUT 1 ring Cut the Py
Axonemal dyenin
hydroxyurea
mRNA is syntehsized in which direction?
Pyrimidines
47. Capping on 5 prime end (7 methylguanosine) -
Alports syndrome
Tumor Suppressors
Neurofilaments
Step one of RNA processing
48. Never go to Go divide rapidly with short G1 bone marrow - gut epithelium - skin - hair follicles
Alternate splicing
intermediate filaments
Labile
microtubule
49. Splicing out of introns
Digoxin (cardiac glycosides)
Termination
Molecular motor protiesn
Step Three of RNA processing
50. 1 RNA polymerase (multisubunite complex) makes all 3 kinds of RNA
Post - translational modifications
Prokaryote RNA pol
Cyclins
Common amino acids in elastin