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First Aid: Biochemistry Molecular

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Inhibits thymidylate synthase down thymine






2. Inhibits the atpase which increases intracellular sodium which increases intracellular calcium increases cardiaccontractility






3. Neuroglia






4. A malfunction of mismatch repair (MUt L etc..)






5. Immotile cilia due to a dyenin arm defect. Results in male nad female inferticility (sperm immotile) - bronchiectasis - and recurrent sinusisits - associated with situs inversus






6. Less condensed - transciptionally active=eu truly transcobed






7. Intervening noncoding segments of DNA






8. The 3 prime hydroxyl of the nascent chain is the target






9. Methionine - which may be removed before translation is completed






10. Site where negative regulators bind






11. RER translation of collagen alpha chains (preprocollagen) usually Gly-X-Y






12. Unwinds DNA template at replication fork






13. 1) primary transcript combines with snRNPs and other proteins to form spliceosome 2) lariat shaped intermediate is generated 3) Lariat is removed and released to precisely join 2 exons






14. Microtubule polymerization defect resulting in lowered phagocytosis. results in recurrent pyogenic infections - partial albinism and peripheral neuropathy






15. Activated by GTP hydrolosis initiation factors help assembel the 40 S ribosomal subunites with the initiatior tRNA and are released whent he mRNA and the ribosomal subunit assemple with the complex






16. UGA - UAG - UAA






17. Responsible for the accuracy of amino acid selection






18. Type III






19. Bind 30S subunit preventing attachment of aminoacyl - tRNA






20. Non homologous end joining






21. Particular sequnece in genomre where DNA replication begins. May be single (prokaryotes) or multiple (eukaryotes)






22. Even 40S 60S =80S






23. Condensed - transciptionally inactive HC- Highly condensed






24. RNA polymerase I makes rRNA - RNA pol II makes mRNA - RNA pol III makes tRNA






25. A site - incoming aminoacyl tRNA - Psite accomodates growing Peptide - E site holds EmplytRNA as it exits






26. Prokaryotic only. Elongates leading strand by adding deoxynucleotides to the 3prime end. Elongates laggin strand. 3 prime to 5 prime exonuclease activity






27. Changed aaconservative - new aa is similar in chemical structure






28. Change resulting in early stop codon






29. In the nucleus after transcitpion and only processed RNA is transporte out of the nucleus






30. Inhibit formation of the initation complex and cause misreading of mRNA






31. Promoter - enhancer - promoter - TATA- transcription initiation site - coding region (including exons and introns) and then the AATAAA






32. Commonly results in dramatic decrease in amount of gene transcribed






33. Genetic bone disorder (brittle bone disease) type 1 colalgen - fractures (during birth) 2) Blue sclerae 3) hearing loss 4) dental imperfections 1:10000 may be confused with child abuse






34. G1 - S - G2 - Mitosis






35. The 3 prime end






36. Same aa often base change in 3rd position of codon






37. Prevents stranges from reannealing






38. H1 string






39. Must be both activated and inactivated for cell cycle to progress






40. Be So Totatally Cool Read Books (bOne - CarTWOlage - Threeticular - Type IV under the floor)






41. The N to C






42. Unmethylated - newly synthesized string is recognized - mismatched nucleotides are removed and the gap is filled and resealed






43. Cleave terminal regions of procollagen to transform into insoluable tropocolagen






44. 1P blocked by chloramphenicaol and macrolide






45. Regulatory proteins that control cell cycle events; phase specific; activated CDKs






46. 1P (blocked by tetracycline)






47. Prokaryotic only. Degrades RNA primer and fills in the gap with DNA (5 prime to 3 prime exonuclease)






48. 9+2 arrangement of microtubules -






49. Phosphorylation - glycosloation - hyderoxylation






50. Specific endonucleases release the oligonucleotide containing damaged bases. DNA polymerase and logase fill and resealt eh gap