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Test your basic knowledge |
First Aid: Biochemistry Molecular
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Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
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study here
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Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Inhibit DNA gyrase (specific prokaryotic topoisomerase)
6MP
missense mutation
Immunohistochemical stains vimentin
Fluoroquinolones
2. Ketone
nucleosid
Eukaroytes
Guanine has a
Silencer
3. Inhibits 50S peptidyl transferase
Chloramphenicol
Which end of a growing DNA strand is the target
GFAP
Free ribosomes
4. Inhibits thymidylate synthase down thymine
Smooth ER
Hydroxylation of which amino acids are attached to Glycine to form collagen
5FU
6MP
5. CUT 1 ring Cut the Py
Macrolides
Pyrimidines
Hereditary non polyposis colorectal cancer
Type IV collagen is an important structural component of...
6. Tansport cellular cargo toward opposite ends of microtubule tracks
Plasma membrane composition
Molecular motor protiesn
Alternate splicing
Griseofulvin
7. Antigout - acts on mts
Cholchicine
What type of collagen is most affected in Ehlers Danlos
Functional organization of the gene
Termination
8. Condensed - transciptionally inactive HC- Highly condensed
Exons
Heterochromatin
nucleosid
Protein synthesis is in which direction
9. Retrograde to microtubules
Digoxin (cardiac glycosides)
Axonemal dyenin
What does the hydroxylation of proline and lysine require
dyenin
10. Prevents stranges from reannealing
Sodium K ATPase
single stranded binding proteinds
Translocation
Ehlers Danlos
11. (A - G) 2 rings Pure As Gold
Eukaroytes
Purines
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
missense mutation
12. Alpha 1 antitrypisn
Single Strand DNA Repair types
Elastase is inhibited by
Fluoroquinolones
What type of collagen is most affected in Ehlers Danlos
13. Attachment of ubiquitin to defective proteinds to tag them for breakdown
Proteosomal degradation
Step Three of RNA processing
Xeroderma pigmentosum
hydroxyurea
14. Anti breast cancer - acts on mts
Exons
Paclitaxil
Axonemal dyenin
Higher the cholesterol or long saturated fatty acid content
15. AD and AR- associated iwth joint dislocation - berry aneurysms - organ rupture
origin of replication
Associations of Ehlers Danlos
alpha amintin
Hereditary non polyposis colorectal cancer
16. Blocks denovo purine synthesis
Double Strand DNA repair
6MP
DNA pol I
Fluoroquinolones
17. Seals
Going APE
DNA ligase
Heterochromatin
Outside the cell what processing must be done in procolalgen
18. Negatively charged DNA loops twice around histone octamers create a nucloesome bead.
DNA pol III
intermediate filaments
tRNA aminoacylation
chromatin structure
19. Connective tissue
Xeroderma pigmentosum
C- G bond
Common amino acids in elastin
Immunohistochemical stains vimentin
20. Anti cancer - act on microtubules
Cell cycle
Pyrimidines
Guanine has a
Vincristine/Vinblastine
21. MRNA
Cilia structure
Tropocollagen cross links between_____ to form____
capped and tail transcript is called
Paclitaxil
22. Cilia - glagella - mitotic spindle - neurons - centrioles
tRNA
DNA/RNA/Protein syntesis direction
Enhancers and silencer may be located_____
microtubule
23. In the nucleus after transcitpion and only processed RNA is transporte out of the nucleus
actin and myosin
Loading tRNA on to ribosome energy requirement
RNA processing in eukaryotes occurs
Ehlers Danlos
24. P53 and RB normally inhibit g1 to S progression
Smooth ER
Tumor Suppressors
What ties teh nucleosome together
Prokaryote RNA pol
25. Never go to Go divide rapidly with short G1 bone marrow - gut epithelium - skin - hair follicles
silent mutation
Methotrexate
Labile
origin of replication
26. DNA And RNA synthesized in the 5-3 direction
DNA/RNA/Protein syntesis direction
The only histone not on the core
Stable (quiescent)
Cell cycle order
27. Hydroxy proline and hydroxylysine
Hydroxylation of which amino acids are attached to Glycine to form collagen
Heterochromatin
Cyclins
Cell cycle order
28. 4 high enrgy bonds
Euchromatin
hydroxyurea
Total energy expenditure requirement for translocation
Alternate splicing
29. Neurons - skeletal - and cardiac muscle - RBCs
The only histone not on the core
Example of permanent cells
Higher the cholesterol or long saturated fatty acid content
Purines
30. Contain the actual genetic information coding for protein
Higher the cholesterol or long saturated fatty acid content
White codon is at the 3 prime end of a tRNA
Exons
Aminoacylt - tRNA synthetase
31. VItamin C
Cyclin - CDK
Prokaryote RNA pol
step two of RNA processing
What does the hydroxylation of proline and lysine require
32. Type III
commaless - non - overlapping
Enhancers and silencer may be located_____
silent mutation
What type of collagen is most affected in Ehlers Danlos
33. Remain in G0 regenerate from stem cells
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
RNA processing in eukaryotes occurs
Permanent cells
methionine is only encoded by
34. Antifungal - act on microtubules
tRNA Structure
commaless - non - overlapping
Osteogenesis Imperfecta
Griseofulvin
35. Strethchy protein within lungs - large artiers - elastic liaments - vocal cords - ligamenta flava)
Elastin
histone octamer names
Which end of the nucleotide has the triphosphate
Type IV collagen is an important structural component of...
36. Different exons can be combined to make nique protiens in different times
Loading tRNA on to ribosome energy requirement
Glycosolation
Alternate splicing
Which end of the nucleotide has the triphosphate
37. Close to - far from or even within (in an intron) the gene whose expression it regulates
origin of replication
Cell cycle
CDKs
Enhancers and silencer may be located_____
38. Anterograde to microtubule
kinesin
desmin
Chloramphenicol
Hydroxylation of which amino acids are attached to Glycine to form collagen
39. 75-90 nucleotides - 2ary structure cloverleaf form anticodon end is opposite 3 prime aminoacyl end
intermediate filaments
tRNA gripping and going places
Free ribosomes
tRNA Structure
40. Site where negative regulators bind
DNA/RNA/Protein syntesis direction
intermediate filaments
What does the hydroxylation of proline and lysine require
Silencer
41. Responsible for the accuracy of amino acid selection
alpha amintin
step two of RNA processing
dyenin
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
42. Genetic code is conserved throughout evolution
Termination
trimethoprim
mRNA stop codons
universal
43. Elastase
Elastin is broken down by
nucleosid
Cilia structure
purines
44. A malfunction of mismatch repair (MUt L etc..)
DNA/RNA/Protein syntesis direction
Sodium K ATPase
microtubule
Hereditary non polyposis colorectal cancer
45. Create a nick in the helix to relieve supercoils created during replication
pyrimadines
Protein synthesis initiation
DNA topoisomerases
hydroxyurea
46. Makes an RNA primer on which DNA polymerase II can initiate replication
Primase
Steps in splicing
the tRNA- amino acid bond
What ties teh nucleosome together
47. RER translation of collagen alpha chains (preprocollagen) usually Gly-X-Y
alpha amintin
Digoxin (cardiac glycosides)
Collagedn synthesis where?
Cyclins
48. Inhibit formation of the initation complex and cause misreading of mRNA
Higher the cholesterol or long saturated fatty acid content
The only histone not on the core
Aminoglycosides
Griseofulvin
49. Greater melting temperature lower fluidity
Which end of a growing DNA strand is the target
AUG codes For what in prokaryotes
kinesin
Higher the cholesterol or long saturated fatty acid content
50. Prokaryotic only. Elongates leading strand by adding deoxynucleotides to the 3prime end. Elongates laggin strand. 3 prime to 5 prime exonuclease activity
DNA pol III
polyadenylation does/does not require a template
Digoxin (cardiac glycosides)
Introns
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