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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Three amino acids necessary for purine synthesis= glutamine - aspartate and glycine
Osteogenesis Imperfecta
Gag on pure gold
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
Vincristine/Vinblastine
2. Condensed - transciptionally inactive HC- Highly condensed
Heterochromatin
What type of collagen is most affected in Ehlers Danlos
Griseofulvin
Alports syndrome
3. Rampant - Massive - TIny rRNA is most common - then mRNA and then tRNA
commaless - non - overlapping
Which is the most and least abundant type of RNA
Enhancers and silencer may be located_____
DNA pol III
4. AD and AR- associated iwth joint dislocation - berry aneurysms - organ rupture
desmin
Termination
Associations of Ehlers Danlos
DNA ligase
5. Responsible for the accuracy of amino acid selection
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
A- T
nonsense
mRNA stop codons
6. Change resulting in early stop codon
Methotrexate
nonsense
Which end of the nucleotide has the triphosphate
Macrolides
7. A site - incoming aminoacyl tRNA - Psite accomodates growing Peptide - E site holds EmplytRNA as it exits
Steps in splicing
microtubule
DNA pol III
Going APE
8. Site where negative regulators bind
What type of collagen is most affected in Ehlers Danlos
Protein synthesis initiation
tRNA
Silencer
9. Aminoacyl - tRNA binds to A site 2) peptidyltransferase catalyzes peptide bond formation transfers growing polypeptie to amino acid in A site 3) ribosome advances 3 nucleotides toward the 3 prime end of RNA moving peptiydyl RNA to P site
Primase
Cell cycle
Total energy expenditure requirement for translocation
Elongation
10. Anti breast cancer - acts on mts
Vincristine/Vinblastine
Translocation
Chloramphenicol
Paclitaxil
11. Neuroglia
Associations of Ehlers Danlos
Kartageners syndrome
GFAP
Tumor Suppressors
12. Phosphorylation - glycosloation - hyderoxylation
Covalent alterations
transversion
cytokeratin
Which is the most and least abundant type of RNA
13. Substituting a purine for a pyrimdine or vice versa
actin and myosin
transversion
tRNA Structure
Total energy expenditure requirement for translocation
14. RER translation of collagen alpha chains (preprocollagen) usually Gly-X-Y
Chloramphenicol
Gag on pure gold
Collagedn synthesis where?
Sodium K ATPase
15. One codon AUG
methionine is only encoded by
C- G bond
pyrimadines
promoter
16. Enter G1 from G0 when stimulated Hepatocytes/lymphocytes
CDKs
Griseofulvin
Stable (quiescent)
Silencer
17. H1
The only histone not on the core
Which is the most and least abundant type of RNA
Translocation
Elongation
18. HS1 - HSB - H2 - H4
Termination
Enhancers and silencer may be located_____
GFAP
histone octamer names
19. Must be both activated and inactivated for cell cycle to progress
Higher the cholesterol or long saturated fatty acid content
step two of RNA processing
Xeroderma pigmentosum
Cyclin - CDK
20. Attachment of ubiquitin to defective proteinds to tag them for breakdown
Rough ER
dyenin
Type IV collagen is an important structural component of...
Proteosomal degradation
21. Splicing out of introns
AUG codes For what in prokaryotes
Post - translational modifications
Elastin
Step Three of RNA processing
22. Site of dteroid synthesis and detoxification of druigs and poisons (liver hepatocytes and steroid horomore adrenal cortex)
helicase
Initial transcript without processing is known as
White codon is at the 3 prime end of a tRNA
Smooth ER
23. Inhibits bacterials dihydrofolate reducatese down thymine
Elastase is inhibited by
Single Strand DNA Repair types
Non homologous end joining
trimethoprim
24. Cleave terminal regions of procollagen to transform into insoluable tropocolagen
Aminoglycosides
Purines
RNA processing in eukaryotes occurs
Outside the cell what processing must be done in procolalgen
25. Tansport cellular cargo toward opposite ends of microtubule tracks
Molecular motor protiesn
tRNA aminoacylation
Tumor Suppressors
Primase
26. Epithelial cells
Cholchicine
Guanine has a
methionine is only encoded by
cytokeratin
27. Change resulting in misreading of all nucleotides downstream - usually resulting in a truncated non functional protien
Osteogenesis Imperfecta
frame shift
transversion
Which end of the nucleotide has the triphosphate
28. Proline - glycine
Cell cycle order
Type IV collagen is an important structural component of...
Which is the most and least abundant type of RNA
Common amino acids in elastin
29. ATP- AMP (2 phosphoanhydride bonds)
tRNA aminoacylation
Cell cycle order
nonsense
Plasma membrane composition
30. AUG inAUGurates protein synthesis
microtubule
mRNA start codons
Cyclin - CDK
Eukaroytes
31. DNA And RNA synthesized in the 5-3 direction
mRNA stop codons
Chloramphenicol
Alternate splicing
DNA/RNA/Protein syntesis direction
32. Connective tissue
hydroxyurea
Immunohistochemical stains vimentin
Which is the most and least abundant type of RNA
Steps in splicing
33. Has enough energy to created the peptide bond
Enhancers and silencer may be located_____
the tRNA- amino acid bond
Gag on pure gold
GFAP
34. Vimentin - desmin - cytockeratin - glial fibrillary acid proteins - neurofilaments
mRNA is syntehsized in which direction?
mRNA stop codons
kinesin
intermediate filaments
35. 3 H bonds
Step Three of RNA processing
C- G bond
Chloramphenicol
Aminoglycosides
36. Microtubule polymerization defect resulting in lowered phagocytosis. results in recurrent pyogenic infections - partial albinism and peripheral neuropathy
Macrolides
Elastase is inhibited by
Chediak Higashi syndrome
Double Strand DNA repair
37. Type III
Smooth ER
actin and myosin
tRNA
What type of collagen is most affected in Ehlers Danlos
38. Inhibits by binding to the potassium side
C- G bond
universal
cytokeratin
Oubain
39. Commonly results in dramatic decrease in amount of gene transcribed
Elastin is broken down by
Promoter mutation
Heterochromatin
alpha amintin
40. Ribonucleotide reductase
Elastin
actin and myosin
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
Cholchicine
41. RNA polymerase I makes rRNA - RNA pol II makes mRNA - RNA pol III makes tRNA
Cilia structure
DNA ligase
Covalent alterations
RNA polymerases in eukaryotes
42. Intervening noncoding segments of DNA
unambiguous
Free ribosomes
Introns
Collagedn synthesis where?
43. Inhibits thymidylate synthase down thymine
silent mutation
5FU
Eukaroytes
polyadenylation does/does not require a template
44. Ketone
Steps in splicing
AUG codes For what in prokaryotes
Molecular motor protiesn
Guanine has a
45. MRNA
Covalent alterations
nonsense
capped and tail transcript is called
White codon is at the 3 prime end of a tRNA
46. Antigout - acts on mts
6MP
pyrimadines
Prokaryote RNA pol
Cholchicine
47. Prokaryotic only. Elongates leading strand by adding deoxynucleotides to the 3prime end. Elongates laggin strand. 3 prime to 5 prime exonuclease activity
DNA/RNA/Protein syntesis direction
Order of mitosis
Cyclins
DNA pol III
48. Different exons can be combined to make nique protiens in different times
Alternate splicing
6MP
Mismatch repair
dyenin
49. Unattached to any membrane; site of cytosolic and organeller prtoeins
What ties teh nucleosome together
Thymine has a
RNA processing in eukaryotes occurs
Free ribosomes
50. Alpha 1 antitrypisn
A- T
Eukaroytes
Elastase is inhibited by
Total energy expenditure requirement for translocation