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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Muscle
mRNA is syntehsized in which direction?
commaless - non - overlapping
desmin
Digoxin (cardiac glycosides)
2. Codes for formyl methionine (f - Met)
Which is the most and least abundant type of RNA
AUG codes For what in prokaryotes
Silencer
tRNA activation
3. Read froma fixed starting point as a continous sequenecs of bases
mRNA start codons
Ehlers Danlos
Guanine has a
commaless - non - overlapping
4. Cilia - glagella - mitotic spindle - neurons - centrioles
Where do introns and exons stay
microtubule
Higher the cholesterol or long saturated fatty acid content
Cholchicine
5. Inhibits dihydrofolate reductase down thymine
Chediak Higashi syndrome
Methotrexate
transition
Step Three of RNA processing
6. RER translation of collagen alpha chains (preprocollagen) usually Gly-X-Y
Elongation
unambiguous
Excocytosis of collagen
Collagedn synthesis where?
7. Intervening noncoding segments of DNA
tRNA gripping and going places
Molecular motor protiesn
Introns
Exons
8. Brings together 2 ends of DNA fragments no requirement for homology
Non homologous end joining
nonsense
White codon is at the 3 prime end of a tRNA
Rough ER
9. Create a nick in the helix to relieve supercoils created during replication
Excocytosis of collagen
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
DNA topoisomerases
Tumor Suppressors
10. Made from orogate precuror with PRPP added later
Protein synthesis is in which direction
Which end of a growing DNA strand is the target
Which end of the tRNA is the amino acid bound to?
pyrimadines
11. Never go to Go divide rapidly with short G1 bone marrow - gut epithelium - skin - hair follicles
In eukaryotes the starting amino acid is...
step two of RNA processing
Labile
Elastase is inhibited by
12. 1 RNA polymerase (multisubunite complex) makes all 3 kinds of RNA
Guanine has a
Chediak Higashi syndrome
Prokaryotes
Prokaryote RNA pol
13. Seals
What does the hydroxylation of proline and lysine require
C- G bond
silent mutation
DNA ligase
14. Hn RNA
Initial transcript without processing is known as
DNA/RNA/Protein syntesis direction
What type of collagen is most affected in Ehlers Danlos
helicase
15. Base + ribose
Non homologous end joining
histone octamer names
nucleosid
the tRNA- amino acid bond
16. Different exons can be combined to make nique protiens in different times
Alternate splicing
Griseofulvin
mRNA is syntehsized in which direction?
Aminoglycosides
17. In the nucleus after transcitpion and only processed RNA is transporte out of the nucleus
Elastin is broken down by
capped and tail transcript is called
silent mutation
RNA processing in eukaryotes occurs
18. Poly adenylation
step two of RNA processing
C- G bond
Deamination of cytosine makes
Ehlers Danlos
19. VItamin C
What does the hydroxylation of proline and lysine require
Protein synthesis is in which direction
Mebendazole/thiabendazole
origin of replication
20. 1P (blocked by tetracycline)
Loading tRNA on to ribosome energy requirement
Eukaroytes
Vincristine/Vinblastine
Nucleotide excision repair
21. (A - G) 2 rings Pure As Gold
Purines
Neurofilaments
Kartageners syndrome
dyenin
22. Checkpoints control transition between phases of cell cycle. regulated by cyclins - CDKs and tumor suppressors. Mitosis (shortest phse)
Plasma membrane composition
Cell cycle
promoter
Elastin
23. Activated by GTP hydrolosis initiation factors help assembel the 40 S ribosomal subunites with the initiatior tRNA and are released whent he mRNA and the ribosomal subunit assemple with the complex
Protein synthesis initiation
histone octamer names
Sodium K ATPase
Proteosomal degradation
24. 75-90 nucleotides - 2ary structure cloverleaf form anticodon end is opposite 3 prime aminoacyl end
Covalent alterations
tRNA Structure
Introns
methionine is only encoded by
25. Change resulting in early stop codon
Total energy expenditure requirement for translocation
nonsense
Aminoacylt - tRNA synthetase
Hereditary non polyposis colorectal cancer
26. Inhibits 50S peptidyl transferase
Chloramphenicol
Stable (quiescent)
microtubule
Proteosomal degradation
27. The 3 prime hydroxyl of the nascent chain is the target
Which end of a growing DNA strand is the target
Chloramphenicol
RNA polymerases in eukaryotes
Guanine has a
28. Substituting a pyramidine for a pyrimadine
Permanent cells
Aminoglycosides
transition
Protein synthesis initiation
29. Connective tissue
Proofreading function in eukaryotic RNA
Nucleotide excision repair
In eukaryotes the starting amino acid is...
Immunohistochemical stains vimentin
30. Site where RNA polymerase and multiple other transciption factors bind to DNA upstream from gene locus (AT rich upstream sequence with TATA and CAAT boxes)
Cilia structure
promoter
Termination
Tropocollagen cross links between_____ to form____
31. Inhibits the atpase which increases intracellular sodium which increases intracellular calcium increases cardiaccontractility
Proofreading function in eukaryotic RNA
RNA polymerases in eukaryotes
RNA processing in eukaryotes occurs
Digoxin (cardiac glycosides)
32. Promoter - enhancer - promoter - TATA- transcription initiation site - coding region (including exons and introns) and then the AATAAA
Functional organization of the gene
Immunohistochemical stains vimentin
What type of collagen is most affected in Ehlers Danlos
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
33. Elastase
transversion
Elastin is broken down by
Type IV collagen is an important structural component of...
Sodium K ATPase
34. 2 H bonds greater GC content greater melting point
A- T
Guanine has a
Which end of a growing DNA strand is the target
Going APE
35. 3 H bonds
What does the hydroxylation of proline and lysine require
C- G bond
Vincristine/Vinblastine
desmin
36. Microvilli - muscle contraction - cytokinesis - adhering juntions
Tetracyclines
actin and myosin
Introns
C- G bond
37. Enter G1 from G0 when stimulated Hepatocytes/lymphocytes
Stable (quiescent)
Which end of the tRNA is the amino acid bound to?
commaless - non - overlapping
5FU
38. Anit helminth - act on microtubules
Cyclins
Hereditary non polyposis colorectal cancer
Gag on pure gold
Mebendazole/thiabendazole
39. RNA polymerase I makes rRNA - RNA pol II makes mRNA - RNA pol III makes tRNA
RNA polymerases in eukaryotes
In eukaryotes the starting amino acid is...
Common amino acids in elastin
White codon is at the 3 prime end of a tRNA
40. Cyclin depndent kinases; consituative and inactive
Step Three of RNA processing
nonsense
Proofreading function in eukaryotic RNA
CDKs
41. UGA - UAG - UAA
histone octamer names
mRNA stop codons
Functional organization of the gene
White codon is at the 3 prime end of a tRNA
42. Hydroxy proline and hydroxylysine
Outside the cell what processing must be done in procolalgen
Glycosolation
Digoxin (cardiac glycosides)
Hydroxylation of which amino acids are attached to Glycine to form collagen
43. Ketone
silent mutation
Guanine has a
Aminoacylt - tRNA synthetase
hydroxyurea
44. Bind 50S blocking translocation
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
promoter
Associations of Ehlers Danlos
Macrolides
45. Blocks denovo purine synthesis
6MP
Translocation
Nucleotide excision repair
Enhancer
46. 5 prime to 3 prime
mRNA is syntehsized in which direction?
Collagedn synthesis where?
Hydroxylation of which amino acids are attached to Glycine to form collagen
Base excision repair
47. Methyl THYmine has a meTHYl
Clindamycin
Digoxin (cardiac glycosides)
Thymine has a
Elastin
48. Antigout - acts on mts
Which end of a growing DNA strand is the target
Gag on pure gold
Cholchicine
Oubain
49. Commonly results in dramatic decrease in amount of gene transcribed
cytokeratin
Promoter mutation
Base excision repair
Elastin
50. Capping on 5 prime end (7 methylguanosine) -
Step one of RNA processing
Griseofulvin
single stranded binding proteinds
Labile