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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Strethchy protein within lungs - large artiers - elastic liaments - vocal cords - ligamenta flava)
Elastin
Protein synthesis is in which direction
single stranded binding proteinds
Higher the cholesterol or long saturated fatty acid content
2. P53 and RB normally inhibit g1 to S progression
Cilia structure
Higher the cholesterol or long saturated fatty acid content
Tumor Suppressors
Guanine has a
3. Ketone
silent mutation
Step Three of RNA processing
Loading tRNA on to ribosome energy requirement
Guanine has a
4. Splicing out of introns
Primase
Step Three of RNA processing
tRNA activation
Order of mitosis
5. Connective tissue
Step one of RNA processing
Collagen
Immunohistochemical stains vimentin
5FU
6. Read froma fixed starting point as a continous sequenecs of bases
Paclitaxil
commaless - non - overlapping
5FU
Hydroxylation of which amino acids are attached to Glycine to form collagen
7. Introns stay In the nucleus whereas EXons EXit and are EXpressed
Osteogenesis Imperfecta
Where do introns and exons stay
intermediate filaments
origin of replication
8. DNA And RNA synthesized in the 5-3 direction
Labile
purines
Smooth ER
DNA/RNA/Protein syntesis direction
9. Inhibits by binding to the potassium side
Oubain
Guanine has a
Prokaryotes
What type of collagen is most affected in Ehlers Danlos
10. Blocks denovo purine synthesis
6MP
Hydroxylation of which amino acids are attached to Glycine to form collagen
Post - translational modifications
Gag on pure gold
11. Methyl THYmine has a meTHYl
Thymine has a
mRNA is syntehsized in which direction?
Xeroderma pigmentosum
Elongation
12. Three amino acids necessary for purine synthesis= glutamine - aspartate and glycine
Macrolides
nucleotide
Gag on pure gold
Step Three of RNA processing
13. RNA polymerase I makes rRNA - RNA pol II makes mRNA - RNA pol III makes tRNA
Example of permanent cells
RNA polymerases in eukaryotes
Fluoroquinolones
Immunohistochemical stains vimentin
14. ATP ase that links peripheral 9 doublets and causes bending of cilium by differential sliding of doublets
Cilia structure
Kartageners syndrome
Axonemal dyenin
Collagen
15. Antigout - acts on mts
Cholchicine
Cilia structure
unambiguous
universal
16. Inhibits bacterials dihydrofolate reducatese down thymine
Going APE
trimethoprim
tRNA
intermediate filaments
17. Inhibits the atpase which increases intracellular sodium which increases intracellular calcium increases cardiaccontractility
Digoxin (cardiac glycosides)
C- G bond
White codon is at the 3 prime end of a tRNA
Elastin
18. Vimentin - desmin - cytockeratin - glial fibrillary acid proteins - neurofilaments
Chloramphenicol
DNA topoisomerases
Osteogenesis Imperfecta
intermediate filaments
19. Substituting a pyramidine for a pyrimadine
Cyclins
Gag on pure gold
transition
Steps in splicing
20. Seals
Outside the cell what processing must be done in procolalgen
purines
DNA ligase
Cholchicine
21. Same aa often base change in 3rd position of codon
silent mutation
Protein synthesis initiation
Plasma membrane composition
step two of RNA processing
22. UGA - UAG - UAA
Prokaryote RNA pol
mRNA stop codons
White codon is at the 3 prime end of a tRNA
silent mutation
23. Genetic bone disorder (brittle bone disease) type 1 colalgen - fractures (during birth) 2) Blue sclerae 3) hearing loss 4) dental imperfections 1:10000 may be confused with child abuse
Which end of the nucleotide has the triphosphate
Collagen
Mebendazole/thiabendazole
Osteogenesis Imperfecta
24. Never go to Go divide rapidly with short G1 bone marrow - gut epithelium - skin - hair follicles
dyenin
Tetracyclines
Labile
Where do introns and exons stay
25. Rampant - Massive - TIny rRNA is most common - then mRNA and then tRNA
alpha amintin
Going APE
Higher the cholesterol or long saturated fatty acid content
Which is the most and least abundant type of RNA
26. Scrutinizes aa before and after it binds to tRNA. If incorrect bond is hydrolyzed.
Tetracyclines
DNA pol III
mRNA is syntehsized in which direction?
Aminoacylt - tRNA synthetase
27. 1P blocked by chloramphenicaol and macrolide
Going APE
Alports syndrome
Translocation
Promoter mutation
28. Checkpoints control transition between phases of cell cycle. regulated by cyclins - CDKs and tumor suppressors. Mitosis (shortest phse)
Which end of a growing DNA strand is the target
Single Strand DNA Repair types
Collagedn synthesis where?
Cell cycle
29. Even 40S 60S =80S
Cyclins
Step one of RNA processing
Eukaroytes
Going APE
30. 1P (blocked by tetracycline)
Loading tRNA on to ribosome energy requirement
frame shift
Labile
commaless - non - overlapping
31. Odd 30S plus 50 S=70S
Sodium K ATPase
Prokaryotes
Permanent cells
Step one of RNA processing
32. Inhibit formation of the initation complex and cause misreading of mRNA
Aminoglycosides
DNA ligase
Protein synthesis initiation
Vincristine/Vinblastine
33. Made from orogate precuror with PRPP added later
6MP
pyrimadines
actin and myosin
microtubule
34. AUG inAUGurates protein synthesis
microtubule
Macrolides
RNA polymerases in eukaryotes
mRNA start codons
35. A site - incoming aminoacyl tRNA - Psite accomodates growing Peptide - E site holds EmplytRNA as it exits
Going APE
Exons
tRNA gripping and going places
DNA pol I
36. Binds 50S blocking translocation
mRNA is syntehsized in which direction?
Clindamycin
pyrimadines
methionine is only encoded by
37. Uracil
Methotrexate
Deamination of cytosine makes
desmin
Macrolides
38. Immotile cilia due to a dyenin arm defect. Results in male nad female inferticility (sperm immotile) - bronchiectasis - and recurrent sinusisits - associated with situs inversus
Common amino acids in elastin
Griseofulvin
cytokeratin
Kartageners syndrome
39. 4 high enrgy bonds
Enhancers and silencer may be located_____
Which is the most and least abundant type of RNA
capped and tail transcript is called
Total energy expenditure requirement for translocation
40. A malfunction of mismatch repair (MUt L etc..)
hydroxyurea
Hereditary non polyposis colorectal cancer
Elongation
Purines
41. CCA AT 3 PRIME END
White codon is at the 3 prime end of a tRNA
AUG codes For what in prokaryotes
dyenin
actin and myosin
42. Type III
What type of collagen is most affected in Ehlers Danlos
DNA pol III
Purines
Oubain
43. Inhibits ribonucleotide reductase
DNA pol III
Smooth ER
Clindamycin
hydroxyurea
44. H1 string
Fluoroquinolones
What ties teh nucleosome together
Guanine has a
Total energy expenditure requirement for translocation
45. Change resulting in early stop codon
nonsense
Smooth ER
The only histone not on the core
Elastin
46. Substituting a purine for a pyrimdine or vice versa
transversion
actin and myosin
origin of replication
Aminoacylt - tRNA synthetase
47. GTP
tRNA gripping and going places
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
Which end of the nucleotide has the triphosphate
Mismatch repair
48. Inhibits 50S peptidyl transferase
alpha amintin
chromatin structure
Chloramphenicol
pyrimadines
49. Neurons
universal
DNA/RNA/Protein syntesis direction
Rough ER
Neurofilaments
50. Inhibit DNA gyrase (specific prokaryotic topoisomerase)
Tropocollagen cross links between_____ to form____
Fluoroquinolones
nucleotide
Cilia structure