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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Microtubule polymerization defect resulting in lowered phagocytosis. results in recurrent pyogenic infections - partial albinism and peripheral neuropathy
Chediak Higashi syndrome
kinesin
Osteogenesis Imperfecta
Tropocollagen cross links between_____ to form____
2. Tansport cellular cargo toward opposite ends of microtubule tracks
Molecular motor protiesn
actin and myosin
Deamination of cytosine makes
mRNA stop codons
3. Anit helminth - act on microtubules
Mebendazole/thiabendazole
DNA topoisomerases
Hereditary non polyposis colorectal cancer
Pyrimidines
4. HS1 - HSB - H2 - H4
histone octamer names
Thymine has a
Elastase is inhibited by
Permanent cells
5. GTP
Step Three of RNA processing
tRNA activation
hydroxyurea
tRNA gripping and going places
6. Regulatory proteins that control cell cycle events; phase specific; activated CDKs
Digoxin (cardiac glycosides)
Cyclins
Glycosolation
Chediak Higashi syndrome
7. Stretch of DNA that alters gene expression by binding transcription factors
nucleotide
transversion
Enhancer
The only histone not on the core
8. No proofreading function but can initiate chains. RNA poymerase II opens DNA at promoter site
Order of mitosis
Proofreading function in eukaryotic RNA
tRNA
RNA polymerases in eukaryotes
9. Site of secretory protiens (mucus secreting goblet cells and antibody secreting cells)
Smooth ER
Rough ER
Digoxin (cardiac glycosides)
Hydroxylation of which amino acids are attached to Glycine to form collagen
10. One codon AUG
The only histone not on the core
methionine is only encoded by
RNA polymerases in eukaryotes
Glycosolation
11. The 5prime end (energy for the bond)
mRNA start codons
What ties teh nucleosome together
Which end of the nucleotide has the triphosphate
Which end of the tRNA is the amino acid bound to?
12. Has enough energy to created the peptide bond
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
mRNA stop codons
Proteosomal degradation
the tRNA- amino acid bond
13. Anterograde to microtubule
Cell cycle
kinesin
Deamination of cytosine makes
Ehlers Danlos
14. 1P (blocked by tetracycline)
Thymine has a
White codon is at the 3 prime end of a tRNA
Loading tRNA on to ribosome energy requirement
GFAP
15. 75-90 nucleotides - 2ary structure cloverleaf form anticodon end is opposite 3 prime aminoacyl end
single stranded binding proteinds
origin of replication
tRNA Structure
In eukaryotes the starting amino acid is...
16. Epithelial cells
cytokeratin
Hereditary non polyposis colorectal cancer
Going APE
Griseofulvin
17. Substituting a purine for a pyrimdine or vice versa
transversion
single stranded binding proteinds
Step Three of RNA processing
histone octamer names
18. Exocytose procollagen into extracellylar sace
Excocytosis of collagen
actin and myosin
Order of mitosis
single stranded binding proteinds
19. Odd 30S plus 50 S=70S
Silencer
DNA pol I
Prokaryotes
promoter
20. Cleave terminal regions of procollagen to transform into insoluable tropocolagen
tRNA Structure
Outside the cell what processing must be done in procolalgen
Which end of the tRNA is the amino acid bound to?
intermediate filaments
21. You glyucosolate hte pro - alpha chain lysine resudens and form procollagen (triple helix of alpha chains)
Glycosolation
Purines
Protein synthesis is in which direction
Tumor Suppressors
22. Capping on 5 prime end (7 methylguanosine) -
Chediak Higashi syndrome
Step one of RNA processing
nucleotide
microtubule
23. Scrutinizes aa before and after it binds to tRNA. If incorrect bond is hydrolyzed.
Collagedn synthesis where?
cytokeratin
Aminoacylt - tRNA synthetase
the tRNA- amino acid bond
24. In the nucleus after transcitpion and only processed RNA is transporte out of the nucleus
capped and tail transcript is called
Deamination of cytosine makes
RNA processing in eukaryotes occurs
Example of permanent cells
25. Change resulting in early stop codon
nonsense
Guanine has a
Termination
Smooth ER
26. Does not
Higher the cholesterol or long saturated fatty acid content
polyadenylation does/does not require a template
tRNA Structure
the tRNA- amino acid bond
27. Rampant - Massive - TIny rRNA is most common - then mRNA and then tRNA
Introns
alpha amintin
Which is the most and least abundant type of RNA
Outside the cell what processing must be done in procolalgen
28. Close to - far from or even within (in an intron) the gene whose expression it regulates
Heterochromatin
Enhancers and silencer may be located_____
Deamination of cytosine makes
Covalent alterations
29. 1) primary transcript combines with snRNPs and other proteins to form spliceosome 2) lariat shaped intermediate is generated 3) Lariat is removed and released to precisely join 2 exons
methionine is only encoded by
Steps in splicing
transition
RNA polymerases in eukaryotes
30. The N to C
Mebendazole/thiabendazole
Protein synthesis is in which direction
Vincristine/Vinblastine
RNA polymerases in eukaryotes
31. Commonly results in dramatic decrease in amount of gene transcribed
Digoxin (cardiac glycosides)
Methotrexate
Translocation
Promoter mutation
32. Immotile cilia due to a dyenin arm defect. Results in male nad female inferticility (sperm immotile) - bronchiectasis - and recurrent sinusisits - associated with situs inversus
Tetracyclines
DNA/RNA/Protein syntesis direction
Kartageners syndrome
Loading tRNA on to ribosome energy requirement
33. AD and AR- associated iwth joint dislocation - berry aneurysms - organ rupture
Associations of Ehlers Danlos
degenerate or redundant
Primase
Sodium K ATPase
34. Made from IMP precursor
purines
chromatin structure
Cilia structure
Plasma membrane composition
35. Alpha 1 antitrypisn
Elastase is inhibited by
Going APE
Exons
Proteosomal degradation
36. Read froma fixed starting point as a continous sequenecs of bases
Step Three of RNA processing
commaless - non - overlapping
Euchromatin
Silencer
37. Bind 50S blocking translocation
Initial transcript without processing is known as
Macrolides
Glycosolation
Cell cycle
38. Even 40S 60S =80S
Eukaroytes
Example of permanent cells
Total energy expenditure requirement for translocation
nucleosid
39. ATP- AMP (2 phosphoanhydride bonds)
Clindamycin
tRNA aminoacylation
A- T
6MP
40. More than 1 codon may code for the same amino acid
Steps in splicing
Immunohistochemical stains vimentin
degenerate or redundant
intermediate filaments
41. Poly adenylation
Cyclin - CDK
Pyrimidines
step two of RNA processing
A- T
42. Non homologous end joining
Excocytosis of collagen
Protein synthesis initiation
Cell cycle
Double Strand DNA repair
43. AUG inAUGurates protein synthesis
Outside the cell what processing must be done in procolalgen
Neurofilaments
capped and tail transcript is called
mRNA start codons
44. Cilia - glagella - mitotic spindle - neurons - centrioles
Cholchicine
Promoter mutation
microtubule
Loading tRNA on to ribosome energy requirement
45. Antifungal - act on microtubules
Outside the cell what processing must be done in procolalgen
Aminoacylt - tRNA synthetase
Griseofulvin
nucleotide
46. Muscle
transition
desmin
Plasma membrane composition
Purines
47. Must be both activated and inactivated for cell cycle to progress
commaless - non - overlapping
Tetracyclines
dyenin
Cyclin - CDK
48. Prevents stranges from reannealing
Labile
C- G bond
Smooth ER
single stranded binding proteinds
49. Xlinked recessive IV collagen bm - kidney - ear and eye -- nephritis and defness ocular disturbances
Alports syndrome
tRNA gripping and going places
Protein synthesis is in which direction
transversion
50. Particular sequnece in genomre where DNA replication begins. May be single (prokaryotes) or multiple (eukaryotes)
Smooth ER
Elastin is broken down by
mRNA stop codons
origin of replication