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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Mutation in nucleotide excision repair Dry skin with melanoma and other cancers
RNA polymerases in eukaryotes
Outside the cell what processing must be done in procolalgen
degenerate or redundant
Xeroderma pigmentosum
2. A site - incoming aminoacyl tRNA - Psite accomodates growing Peptide - E site holds EmplytRNA as it exits
nucleotide
Elastin
Going APE
Silencer
3. Microvilli - muscle contraction - cytokinesis - adhering juntions
the tRNA- amino acid bond
Steps in splicing
actin and myosin
dyenin
4. Cyclin depndent kinases; consituative and inactive
Stable (quiescent)
CDKs
tRNA activation
Steps in splicing
5. Site of secretory protiens (mucus secreting goblet cells and antibody secreting cells)
Rough ER
desmin
Collagedn synthesis where?
Purines
6. 2 H bonds greater GC content greater melting point
Nucleotide excision repair
Non homologous end joining
The only histone not on the core
A- T
7. Site where negative regulators bind
Eukaroytes
frame shift
single stranded binding proteinds
Silencer
8. Bind 30S subunit preventing attachment of aminoacyl - tRNA
The only histone not on the core
Elongation
Silencer
Tetracyclines
9. Prophas - metaphase - anaphase telophase
Collagen
step two of RNA processing
universal
Order of mitosis
10. Even 40S 60S =80S
Labile
Eukaroytes
Protein synthesis initiation
Cyclins
11. Each codon specifies only 1 amino acid
Termination
5FU
unambiguous
Hereditary non polyposis colorectal cancer
12. Binds 50S blocking translocation
In eukaryotes the starting amino acid is...
chromatin structure
Step Three of RNA processing
Clindamycin
13. Site of dteroid synthesis and detoxification of druigs and poisons (liver hepatocytes and steroid horomore adrenal cortex)
Promoter mutation
Protein synthesis initiation
Smooth ER
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
14. Does not
polyadenylation does/does not require a template
The only histone not on the core
frame shift
Cholchicine
15. Inhibits 50S peptidyl transferase
Chloramphenicol
Proofreading function in eukaryotic RNA
6MP
Going APE
16. Specific endonucleases release the oligonucleotide containing damaged bases. DNA polymerase and logase fill and resealt eh gap
Nucleotide excision repair
chromatin structure
Elongation
Which end of the nucleotide has the triphosphate
17. You glyucosolate hte pro - alpha chain lysine resudens and form procollagen (triple helix of alpha chains)
Glycosolation
Plasma membrane composition
chromatin structure
microtubule
18. Xlinked recessive IV collagen bm - kidney - ear and eye -- nephritis and defness ocular disturbances
Proofreading function in eukaryotic RNA
Exons
DNA topoisomerases
Alports syndrome
19. Close to - far from or even within (in an intron) the gene whose expression it regulates
Cilia structure
Tetracyclines
Enhancers and silencer may be located_____
dyenin
20. Greater melting temperature lower fluidity
Stable (quiescent)
Higher the cholesterol or long saturated fatty acid content
Collagen
Aminoacylt - tRNA synthetase
21. Base + ribose
silent mutation
intermediate filaments
kinesin
nucleosid
22. Immotile cilia due to a dyenin arm defect. Results in male nad female inferticility (sperm immotile) - bronchiectasis - and recurrent sinusisits - associated with situs inversus
Tetracyclines
Kartageners syndrome
Type IV collagen is an important structural component of...
trimethoprim
23. Brings together 2 ends of DNA fragments no requirement for homology
Non homologous end joining
Kartageners syndrome
kinesin
mRNA stop codons
24. Inhibits dihydrofolate reductase down thymine
pyrimadines
Methotrexate
CDKs
AUG codes For what in prokaryotes
25. Genetic bone disorder (brittle bone disease) type 1 colalgen - fractures (during birth) 2) Blue sclerae 3) hearing loss 4) dental imperfections 1:10000 may be confused with child abuse
Osteogenesis Imperfecta
GFAP
Digoxin (cardiac glycosides)
DNA topoisomerases
26. Prokaryotic only. Elongates leading strand by adding deoxynucleotides to the 3prime end. Elongates laggin strand. 3 prime to 5 prime exonuclease activity
dyenin
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
microtubule
DNA pol III
27. Vimentin - desmin - cytockeratin - glial fibrillary acid proteins - neurofilaments
Single Strand DNA Repair types
Example of permanent cells
Heterochromatin
intermediate filaments
28. Neurons
alpha amintin
Neurofilaments
CDKs
Pyrimidines
29. 75-90 nucleotides - 2ary structure cloverleaf form anticodon end is opposite 3 prime aminoacyl end
Eukaroytes
nonsense
RNA processing in eukaryotes occurs
tRNA Structure
30. H1 string
transversion
Alports syndrome
What does the hydroxylation of proline and lysine require
What ties teh nucleosome together
31. Completed protein is released from ribosme through simple hydrolosis and dissociates
Ehlers Danlos
Non homologous end joining
Termination
Total energy expenditure requirement for translocation
32. Made from orogate precuror with PRPP added later
pyrimadines
Which end of a growing DNA strand is the target
promoter
Eukaroytes
33. Prokaryotic only. Degrades RNA primer and fills in the gap with DNA (5 prime to 3 prime exonuclease)
Stable (quiescent)
actin and myosin
Mebendazole/thiabendazole
DNA pol I
34. Makes an RNA primer on which DNA polymerase II can initiate replication
Alports syndrome
Labile
Primase
What does the hydroxylation of proline and lysine require
35. Site where RNA polymerase and multiple other transciption factors bind to DNA upstream from gene locus (AT rich upstream sequence with TATA and CAAT boxes)
Fluoroquinolones
tRNA aminoacylation
trimethoprim
promoter
36. 9+2 arrangement of microtubules -
AUG codes For what in prokaryotes
helicase
chromatin structure
Cilia structure
37. 3 H bonds
AUG codes For what in prokaryotes
mRNA is syntehsized in which direction?
C- G bond
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
38. Unattached to any membrane; site of cytosolic and organeller prtoeins
Fluoroquinolones
mRNA is syntehsized in which direction?
Free ribosomes
promoter
39. VItamin C
Thymine has a
What does the hydroxylation of proline and lysine require
RNA processing in eukaryotes occurs
unambiguous
40. The 3 prime end
Which end of the tRNA is the amino acid bound to?
Euchromatin
Kartageners syndrome
Methotrexate
41. Made from IMP precursor
purines
DNA pol III
degenerate or redundant
tRNA aminoacylation
42. CUT 1 ring Cut the Py
Gag on pure gold
Pyrimidines
Covalent alterations
Common amino acids in elastin
43. Cleave terminal regions of procollagen to transform into insoluable tropocolagen
Digoxin (cardiac glycosides)
RNA polymerases in eukaryotes
Double Strand DNA repair
Outside the cell what processing must be done in procolalgen
44. Change resulting in misreading of all nucleotides downstream - usually resulting in a truncated non functional protien
Collagedn synthesis where?
frame shift
Prokaryotes
Functional organization of the gene
45. Elastase
Prokaryotes
Elastin is broken down by
Guanine has a
Labile
46. Substituting a purine for a pyrimdine or vice versa
Non homologous end joining
Enhancers and silencer may be located_____
DNA ligase
transversion
47. Codes for formyl methionine (f - Met)
AUG codes For what in prokaryotes
Functional organization of the gene
Proteosomal degradation
Silencer
48. Splicing out of introns
RNA polymerases in eukaryotes
Ehlers Danlos
nucleosid
Step Three of RNA processing
49. Responsible for the accuracy of amino acid selection
Guanine has a
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
Euchromatin
Alternate splicing
50. G1 - S - G2 - Mitosis
RNA processing in eukaryotes occurs
Cell cycle order
DNA pol I
purines