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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Prokaryotic only. Elongates leading strand by adding deoxynucleotides to the 3prime end. Elongates laggin strand. 3 prime to 5 prime exonuclease activity
Eukaroytes
DNA pol III
Initial transcript without processing is known as
tRNA Structure
2. Retrograde to microtubules
What ties teh nucleosome together
dyenin
Fluoroquinolones
the tRNA- amino acid bond
3. Checkpoints control transition between phases of cell cycle. regulated by cyclins - CDKs and tumor suppressors. Mitosis (shortest phse)
origin of replication
Cyclin - CDK
histone octamer names
Cell cycle
4. Bm - kidney - ears and eyes
C- G bond
Introns
5FU
Type IV collagen is an important structural component of...
5. Neurons
Neurofilaments
promoter
microtubule
Double Strand DNA repair
6. Neuroglia
GFAP
cytokeratin
Prokaryotes
commaless - non - overlapping
7. Cilia - glagella - mitotic spindle - neurons - centrioles
Elongation
Hydroxylation of which amino acids are attached to Glycine to form collagen
microtubule
White codon is at the 3 prime end of a tRNA
8. Inhibits thymidylate synthase down thymine
5FU
Heterochromatin
In eukaryotes the starting amino acid is...
Promoter mutation
9. 1 RNA polymerase (multisubunite complex) makes all 3 kinds of RNA
Guanine has a
Replication fork
Prokaryote RNA pol
Double Strand DNA repair
10. Introns stay In the nucleus whereas EXons EXit and are EXpressed
universal
Nucleotide excision repair
Where do introns and exons stay
Excocytosis of collagen
11. ATP
Hereditary non polyposis colorectal cancer
tRNA
Labile
tRNA activation
12. Completed protein is released from ribosme through simple hydrolosis and dissociates
Elongation
Termination
Type IV collagen is an important structural component of...
Proofreading function in eukaryotic RNA
13. H1
Proofreading function in eukaryotic RNA
Glycosolation
Which is the most and least abundant type of RNA
The only histone not on the core
14. Attachment of ubiquitin to defective proteinds to tag them for breakdown
Purines
Proteosomal degradation
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
Where do introns and exons stay
15. 3 sodium out for 2 potassium in (nout - kin)takes 1 atp and the machine is phosphorylated during the machine cycle
Sodium K ATPase
Tumor Suppressors
nucleosid
pyrimadines
16. Genetic code is conserved throughout evolution
universal
purines
Elastase is inhibited by
Where do introns and exons stay
17. P53 and RB normally inhibit g1 to S progression
Tumor Suppressors
Functional organization of the gene
desmin
nonsense
18. Connective tissue
Fluoroquinolones
Immunohistochemical stains vimentin
Eukaroytes
mRNA is syntehsized in which direction?
19. Cylindrical structure composed of helical array of plymerized dimers of alpha and beta tubulin - flagella - cilia - mitotic spindle - grows slowly collapses quickly
microtubule
Enhancers and silencer may be located_____
Outside the cell what processing must be done in procolalgen
Replication fork
20. Change resulting in early stop codon
AUG codes For what in prokaryotes
nonsense
Loading tRNA on to ribosome energy requirement
DNA pol III
21. Inhibit formation of the initation complex and cause misreading of mRNA
Elastin
Aminoglycosides
Collagen
What does the hydroxylation of proline and lysine require
22. ATP ase that links peripheral 9 doublets and causes bending of cilium by differential sliding of doublets
Elastin is broken down by
Axonemal dyenin
Step Three of RNA processing
Smooth ER
23. Phosphorylation - glycosloation - hyderoxylation
step two of RNA processing
missense mutation
mRNA is syntehsized in which direction?
Covalent alterations
24. Makes an RNA primer on which DNA polymerase II can initiate replication
step two of RNA processing
tRNA aminoacylation
Primase
hydroxyurea
25. Microvilli - muscle contraction - cytokinesis - adhering juntions
actin and myosin
Elongation
Replication fork
histone octamer names
26. Type III
Tumor Suppressors
Which end of a growing DNA strand is the target
What type of collagen is most affected in Ehlers Danlos
silent mutation
27. More than 1 codon may code for the same amino acid
Deamination of cytosine makes
Tetracyclines
degenerate or redundant
Permanent cells
28. Anti cancer - act on microtubules
Vincristine/Vinblastine
Immunohistochemical stains vimentin
Associations of Ehlers Danlos
Oubain
29. Methionine - which may be removed before translation is completed
Clindamycin
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
Sodium K ATPase
In eukaryotes the starting amino acid is...
30. Inhibits bacterials dihydrofolate reducatese down thymine
Hydroxylation of which amino acids are attached to Glycine to form collagen
Aminoglycosides
trimethoprim
mRNA stop codons
31. Genetic bone disorder (brittle bone disease) type 1 colalgen - fractures (during birth) 2) Blue sclerae 3) hearing loss 4) dental imperfections 1:10000 may be confused with child abuse
Osteogenesis Imperfecta
Enhancers and silencer may be located_____
Chediak Higashi syndrome
trimethoprim
32. Antigout - acts on mts
mRNA start codons
Cholchicine
Excocytosis of collagen
DNA topoisomerases
33. Aminoacyl - tRNA binds to A site 2) peptidyltransferase catalyzes peptide bond formation transfers growing polypeptie to amino acid in A site 3) ribosome advances 3 nucleotides toward the 3 prime end of RNA moving peptiydyl RNA to P site
Mebendazole/thiabendazole
Single Strand DNA Repair types
cytokeratin
Elongation
34. Each codon specifies only 1 amino acid
Which end of the nucleotide has the triphosphate
unambiguous
desmin
Exons
35. Stretch of DNA that alters gene expression by binding transcription factors
Base excision repair
kinesin
Enhancer
The only histone not on the core
36. Muscle
Going APE
Glycosolation
cytokeratin
desmin
37. Y shaped region along DNA template where leading and lagging strands are syntehsized
Tetracyclines
Outside the cell what processing must be done in procolalgen
Exons
Replication fork
38. Site where negative regulators bind
Order of mitosis
CDKs
Silencer
DNA/RNA/Protein syntesis direction
39. Neurons - skeletal - and cardiac muscle - RBCs
Where do introns and exons stay
Xeroderma pigmentosum
Example of permanent cells
A- T
40. 75-90 nucleotides - 2ary structure cloverleaf form anticodon end is opposite 3 prime aminoacyl end
Kartageners syndrome
tRNA Structure
Deamination of cytosine makes
6MP
41. No proofreading function but can initiate chains. RNA poymerase II opens DNA at promoter site
Chloramphenicol
RNA processing in eukaryotes occurs
tRNA aminoacylation
Proofreading function in eukaryotic RNA
42. 2 H bonds greater GC content greater melting point
DNA pol I
A- T
Permanent cells
microtubule
43. Site where RNA polymerase and multiple other transciption factors bind to DNA upstream from gene locus (AT rich upstream sequence with TATA and CAAT boxes)
step two of RNA processing
chromatin structure
promoter
Common amino acids in elastin
44. Unmethylated - newly synthesized string is recognized - mismatched nucleotides are removed and the gap is filled and resealed
Chloramphenicol
Mismatch repair
Tumor Suppressors
Euchromatin
45. Site of dteroid synthesis and detoxification of druigs and poisons (liver hepatocytes and steroid horomore adrenal cortex)
methionine is only encoded by
the tRNA- amino acid bond
Smooth ER
5FU
46. The N to C
Digoxin (cardiac glycosides)
unambiguous
Vincristine/Vinblastine
Protein synthesis is in which direction
47. Specific endonucleases release the oligonucleotide containing damaged bases. DNA polymerase and logase fill and resealt eh gap
Cholchicine
tRNA Structure
Molecular motor protiesn
Nucleotide excision repair
48. Cyclin depndent kinases; consituative and inactive
6MP
CDKs
What ties teh nucleosome together
Termination
49. You glyucosolate hte pro - alpha chain lysine resudens and form procollagen (triple helix of alpha chains)
kinesin
Glycosolation
Cell cycle
Free ribosomes
50. Ketone
frame shift
actin and myosin
What ties teh nucleosome together
Guanine has a