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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. 75-90 nucleotides - 2ary structure cloverleaf form anticodon end is opposite 3 prime aminoacyl end
mRNA stop codons
DNA pol I
tRNA Structure
Excocytosis of collagen
2. Phosphorylation - glycosloation - hyderoxylation
Labile
Tetracyclines
Elongation
Covalent alterations
3. Inhibits bacterials dihydrofolate reducatese down thymine
pyrimadines
Total energy expenditure requirement for translocation
Macrolides
trimethoprim
4. Asymmetric fluid bilayer - contains - cholesterol - phospholipids - sphingoplipids - glycolipids - and protiends
nonsense
Proofreading function in eukaryotic RNA
Collagedn synthesis where?
Plasma membrane composition
5. Epithelial cells
Plasma membrane composition
Single Strand DNA Repair types
Purines
cytokeratin
6. Antifungal - act on microtubules
Cholchicine
transversion
C- G bond
Griseofulvin
7. Substituting a purine for a pyrimdine or vice versa
Translocation
Exons
Heterochromatin
transversion
8. VItamin C
Smooth ER
What does the hydroxylation of proline and lysine require
Steps in splicing
Post - translational modifications
9. Be So Totatally Cool Read Books (bOne - CarTWOlage - Threeticular - Type IV under the floor)
Loading tRNA on to ribosome energy requirement
Collagen
Introns
missense mutation
10. Introns stay In the nucleus whereas EXons EXit and are EXpressed
Where do introns and exons stay
Double Strand DNA repair
Which end of a growing DNA strand is the target
Tropocollagen cross links between_____ to form____
11. Inhibits 50S peptidyl transferase
missense mutation
Glycosolation
Gag on pure gold
Chloramphenicol
12. Specific glycosylases recognize and remove damaged bases - AP endonuclease cuts DNA at pyrimidne site - empty sugar is removed and the gap is filled and resealed
kinesin
Base excision repair
Oubain
Chloramphenicol
13. In the nucleus after transcitpion and only processed RNA is transporte out of the nucleus
Xeroderma pigmentosum
mRNA is syntehsized in which direction?
Digoxin (cardiac glycosides)
RNA processing in eukaryotes occurs
14. Immotile cilia due to a dyenin arm defect. Results in male nad female inferticility (sperm immotile) - bronchiectasis - and recurrent sinusisits - associated with situs inversus
nucleotide
Proteosomal degradation
What type of collagen is most affected in Ehlers Danlos
Kartageners syndrome
15. Faulty collagen synthesis causing 1) hyperextensible skin 2) tendency to bleed 3) hypermobile joints
Euchromatin
Glycosolation
Immunohistochemical stains vimentin
Ehlers Danlos
16. HS1 - HSB - H2 - H4
histone octamer names
Translocation
Mismatch repair
Alports syndrome
17. No proofreading function but can initiate chains. RNA poymerase II opens DNA at promoter site
Proofreading function in eukaryotic RNA
Post - translational modifications
Heterochromatin
Primase
18. Changed aaconservative - new aa is similar in chemical structure
Double Strand DNA repair
GFAP
Deamination of cytosine makes
missense mutation
19. Inhibits the atpase which increases intracellular sodium which increases intracellular calcium increases cardiaccontractility
Excocytosis of collagen
Digoxin (cardiac glycosides)
CDKs
Higher the cholesterol or long saturated fatty acid content
20. Genetic code is conserved throughout evolution
Free ribosomes
Hydroxylation of which amino acids are attached to Glycine to form collagen
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
universal
21. Tansport cellular cargo toward opposite ends of microtubule tracks
microtubule
Non homologous end joining
Axonemal dyenin
Molecular motor protiesn
22. Neurons
Elastase is inhibited by
Neurofilaments
A- T
Digoxin (cardiac glycosides)
23. Aminoacyl - tRNA binds to A site 2) peptidyltransferase catalyzes peptide bond formation transfers growing polypeptie to amino acid in A site 3) ribosome advances 3 nucleotides toward the 3 prime end of RNA moving peptiydyl RNA to P site
Which end of the tRNA is the amino acid bound to?
step two of RNA processing
Elongation
Immunohistochemical stains vimentin
24. The 3 prime hydroxyl of the nascent chain is the target
promoter
RNA polymerases in eukaryotes
Which end of a growing DNA strand is the target
Heterochromatin
25. Unwinds DNA template at replication fork
Termination
helicase
the tRNA- amino acid bond
Cilia structure
26. Never go to Go divide rapidly with short G1 bone marrow - gut epithelium - skin - hair follicles
Total energy expenditure requirement for translocation
Covalent alterations
Labile
Cilia structure
27. Base+ribose+phosphate linked by a phosphodiester bond
Loading tRNA on to ribosome energy requirement
Immunohistochemical stains vimentin
nucleotide
trimethoprim
28. You glyucosolate hte pro - alpha chain lysine resudens and form procollagen (triple helix of alpha chains)
Glycosolation
commaless - non - overlapping
helicase
Tumor Suppressors
29. 3 sodium out for 2 potassium in (nout - kin)takes 1 atp and the machine is phosphorylated during the machine cycle
Sodium K ATPase
Purines
Prokaryotes
Steps in splicing
30. Scrutinizes aa before and after it binds to tRNA. If incorrect bond is hydrolyzed.
DNA/RNA/Protein syntesis direction
Aminoacylt - tRNA synthetase
CDKs
purines
31. Neurons - skeletal - and cardiac muscle - RBCs
Protein synthesis is in which direction
Purines
Example of permanent cells
Neurofilaments
32. Made from orogate precuror with PRPP added later
silent mutation
pyrimadines
Heterochromatin
RNA polymerases in eukaryotes
33. Nucleotide excision repair - Base Excision repair - Mismath repair
Proofreading function in eukaryotic RNA
Single Strand DNA Repair types
Methotrexate
Cyclins
34. Promoter - enhancer - promoter - TATA- transcription initiation site - coding region (including exons and introns) and then the AATAAA
Macrolides
Common amino acids in elastin
Functional organization of the gene
Stable (quiescent)
35. Bm - kidney - ears and eyes
Type IV collagen is an important structural component of...
Double Strand DNA repair
Cyclins
chromatin structure
36. Same aa often base change in 3rd position of codon
silent mutation
Methotrexate
Macrolides
Osteogenesis Imperfecta
37. P53 and RB normally inhibit g1 to S progression
microtubule
White codon is at the 3 prime end of a tRNA
Type IV collagen is an important structural component of...
Tumor Suppressors
38. Non homologous end joining
Double Strand DNA repair
CDKs
Plasma membrane composition
transition
39. Must be both activated and inactivated for cell cycle to progress
What does the hydroxylation of proline and lysine require
Collagen
missense mutation
Cyclin - CDK
40. Blocks denovo purine synthesis
6MP
Elastin is broken down by
Rough ER
frame shift
41. AUG inAUGurates protein synthesis
mRNA start codons
Cell cycle order
Methotrexate
Ehlers Danlos
42. Does not
DNA/RNA/Protein syntesis direction
trimethoprim
polyadenylation does/does not require a template
helicase
43. Hn RNA
Vincristine/Vinblastine
Total energy expenditure requirement for translocation
desmin
Initial transcript without processing is known as
44. Prokaryotic only. Degrades RNA primer and fills in the gap with DNA (5 prime to 3 prime exonuclease)
DNA pol I
Axonemal dyenin
single stranded binding proteinds
kinesin
45. Rampant - Massive - TIny rRNA is most common - then mRNA and then tRNA
DNA topoisomerases
Hydroxylation of which amino acids are attached to Glycine to form collagen
Which is the most and least abundant type of RNA
What does the hydroxylation of proline and lysine require
46. Contain the actual genetic information coding for protein
Exons
RNA polymerases in eukaryotes
tRNA aminoacylation
Collagedn synthesis where?
47. Attachment of ubiquitin to defective proteinds to tag them for breakdown
Proteosomal degradation
mRNA is syntehsized in which direction?
Going APE
Cholchicine
48. Each codon specifies only 1 amino acid
In eukaryotes the starting amino acid is...
unambiguous
Primase
transversion
49. Prophas - metaphase - anaphase telophase
Paclitaxil
Order of mitosis
nucleosid
Termination
50. Hydroxy proline and hydroxylysine
Kartageners syndrome
Hydroxylation of which amino acids are attached to Glycine to form collagen
Double Strand DNA repair
Oubain