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First Aid: Biochemistry Molecular

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Hydroxy proline and hydroxylysine






2. Prokaryotic only. Degrades RNA primer and fills in the gap with DNA (5 prime to 3 prime exonuclease)






3. Specific endonucleases release the oligonucleotide containing damaged bases. DNA polymerase and logase fill and resealt eh gap






4. Base + ribose






5. Checkpoints control transition between phases of cell cycle. regulated by cyclins - CDKs and tumor suppressors. Mitosis (shortest phse)






6. MRNA






7. Anti cancer - act on microtubules






8. 3 H bonds






9. Create a nick in the helix to relieve supercoils created during replication






10. One codon AUG






11. Anit helminth - act on microtubules






12. Aminoacyl - tRNA binds to A site 2) peptidyltransferase catalyzes peptide bond formation transfers growing polypeptie to amino acid in A site 3) ribosome advances 3 nucleotides toward the 3 prime end of RNA moving peptiydyl RNA to P site






13. Has enough energy to created the peptide bond






14. 75-90 nucleotides - 2ary structure cloverleaf form anticodon end is opposite 3 prime aminoacyl end






15. The 3 prime end






16. Promoter - enhancer - promoter - TATA- transcription initiation site - coding region (including exons and introns) and then the AATAAA






17. Inhbits RNA pol II (found in death cap mushrooms)






18. A site - incoming aminoacyl tRNA - Psite accomodates growing Peptide - E site holds EmplytRNA as it exits






19. Hn RNA






20. Bm - kidney - ears and eyes






21. Lysine/hydroxylysine and combines to form collagen






22. Anterograde to microtubule






23. Completed protein is released from ribosme through simple hydrolosis and dissociates






24. 1P (blocked by tetracycline)






25. AD and AR- associated iwth joint dislocation - berry aneurysms - organ rupture






26. Faulty collagen synthesis causing 1) hyperextensible skin 2) tendency to bleed 3) hypermobile joints






27. Changed aaconservative - new aa is similar in chemical structure






28. Condensed - transciptionally inactive HC- Highly condensed






29. Cyclin depndent kinases; consituative and inactive






30. Never go to Go divide rapidly with short G1 bone marrow - gut epithelium - skin - hair follicles






31. No proofreading function but can initiate chains. RNA poymerase II opens DNA at promoter site






32. Elastase






33. Poly adenylation






34. Inhibits by binding to the potassium side






35. Site where RNA polymerase and multiple other transciption factors bind to DNA upstream from gene locus (AT rich upstream sequence with TATA and CAAT boxes)






36. Neuroglia






37. Xlinked recessive IV collagen bm - kidney - ear and eye -- nephritis and defness ocular disturbances






38. Inhibits the atpase which increases intracellular sodium which increases intracellular calcium increases cardiaccontractility






39. Less condensed - transciptionally active=eu truly transcobed






40. Muscle






41. Binds 50S blocking translocation






42. Particular sequnece in genomre where DNA replication begins. May be single (prokaryotes) or multiple (eukaryotes)






43. Seals






44. Change resulting in misreading of all nucleotides downstream - usually resulting in a truncated non functional protien






45. Unattached to any membrane; site of cytosolic and organeller prtoeins






46. 3 sodium out for 2 potassium in (nout - kin)takes 1 atp and the machine is phosphorylated during the machine cycle






47. Ketone






48. 5 prime to 3 prime






49. The 3 prime hydroxyl of the nascent chain is the target






50. In the nucleus after transcitpion and only processed RNA is transporte out of the nucleus