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First Aid: Biochemistry Molecular

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. 1P (blocked by tetracycline)






2. Prokaryotic only. Elongates leading strand by adding deoxynucleotides to the 3prime end. Elongates laggin strand. 3 prime to 5 prime exonuclease activity






3. Cyclin depndent kinases; consituative and inactive






4. Change resulting in misreading of all nucleotides downstream - usually resulting in a truncated non functional protien






5. Never go to Go divide rapidly with short G1 bone marrow - gut epithelium - skin - hair follicles






6. Inhibits bacterials dihydrofolate reducatese down thymine






7. 3 sodium out for 2 potassium in (nout - kin)takes 1 atp and the machine is phosphorylated during the machine cycle






8. UGA - UAG - UAA






9. Type III






10. ATP






11. Change resulting in early stop codon






12. Prokaryotic only. Degrades RNA primer and fills in the gap with DNA (5 prime to 3 prime exonuclease)






13. HS1 - HSB - H2 - H4






14. Changed aaconservative - new aa is similar in chemical structure






15. Specific endonucleases release the oligonucleotide containing damaged bases. DNA polymerase and logase fill and resealt eh gap






16. Prevents stranges from reannealing






17. 1P blocked by chloramphenicaol and macrolide






18. Hn RNA






19. 1) primary transcript combines with snRNPs and other proteins to form spliceosome 2) lariat shaped intermediate is generated 3) Lariat is removed and released to precisely join 2 exons






20. Same aa often base change in 3rd position of codon






21. Non homologous end joining






22. Promoter - enhancer - promoter - TATA- transcription initiation site - coding region (including exons and introns) and then the AATAAA






23. Bind 30S subunit preventing attachment of aminoacyl - tRNA






24. Be So Totatally Cool Read Books (bOne - CarTWOlage - Threeticular - Type IV under the floor)






25. Substituting a pyramidine for a pyrimadine






26. Binds 50S blocking translocation






27. One codon AUG






28. Antifungal - act on microtubules






29. You glyucosolate hte pro - alpha chain lysine resudens and form procollagen (triple helix of alpha chains)






30. Hydroxy proline and hydroxylysine






31. Base + ribose






32. Inhibit DNA gyrase (specific prokaryotic topoisomerase)






33. Specific glycosylases recognize and remove damaged bases - AP endonuclease cuts DNA at pyrimidne site - empty sugar is removed and the gap is filled and resealed






34. Responsible for the accuracy of amino acid selection






35. Does not






36. P53 and RB normally inhibit g1 to S progression






37. Enter G1 from G0 when stimulated Hepatocytes/lymphocytes






38. Accurate base pairing is required only in the first 2 nucleotide positions of an mRNA so codons differing ht e3rd wobble psoition may code for the same tRNA/amino acid code






39. Anit helminth - act on microtubules






40. Poly adenylation






41. Proline - glycine






42. More than 1 codon may code for the same amino acid






43. Anti cancer - act on microtubules






44. 1 RNA polymerase (multisubunite complex) makes all 3 kinds of RNA






45. Read froma fixed starting point as a continous sequenecs of bases






46. Mutation in nucleotide excision repair Dry skin with melanoma and other cancers






47. Negatively charged DNA loops twice around histone octamers create a nucloesome bead.






48. Odd 30S plus 50 S=70S






49. Aminoacyl - tRNA binds to A site 2) peptidyltransferase catalyzes peptide bond formation transfers growing polypeptie to amino acid in A site 3) ribosome advances 3 nucleotides toward the 3 prime end of RNA moving peptiydyl RNA to P site






50. G1 - S - G2 - Mitosis