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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Site where negative regulators bind
Silencer
Promoter mutation
Oubain
Steps in splicing
2. Read froma fixed starting point as a continous sequenecs of bases
commaless - non - overlapping
Alternate splicing
Purines
Permanent cells
3. Methyl THYmine has a meTHYl
Protein synthesis is in which direction
Cell cycle
Associations of Ehlers Danlos
Thymine has a
4. Inhibit DNA gyrase (specific prokaryotic topoisomerase)
tRNA
Fluoroquinolones
transition
Glycosolation
5. Elastase
Order of mitosis
Hereditary non polyposis colorectal cancer
Primase
Elastin is broken down by
6. You glyucosolate hte pro - alpha chain lysine resudens and form procollagen (triple helix of alpha chains)
Glycosolation
Cyclin - CDK
Elongation
The only histone not on the core
7. Prophas - metaphase - anaphase telophase
Exons
Permanent cells
Order of mitosis
Elastin
8. Faulty collagen synthesis causing 1) hyperextensible skin 2) tendency to bleed 3) hypermobile joints
What ties teh nucleosome together
Ehlers Danlos
kinesin
microtubule
9. AUG inAUGurates protein synthesis
mRNA start codons
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
Nucleotide excision repair
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
10. Blocks denovo purine synthesis
Neurofilaments
Clindamycin
6MP
Mismatch repair
11. 2 H bonds greater GC content greater melting point
Outside the cell what processing must be done in procolalgen
Plasma membrane composition
Vincristine/Vinblastine
A- T
12. Inhbits RNA pol II (found in death cap mushrooms)
alpha amintin
methionine is only encoded by
Fluoroquinolones
actin and myosin
13. Particular sequnece in genomre where DNA replication begins. May be single (prokaryotes) or multiple (eukaryotes)
What type of collagen is most affected in Ehlers Danlos
missense mutation
origin of replication
trimethoprim
14. Must be both activated and inactivated for cell cycle to progress
polyadenylation does/does not require a template
Cyclin - CDK
Tumor Suppressors
Introns
15. Anterograde to microtubule
Cholchicine
kinesin
Which end of the nucleotide has the triphosphate
Griseofulvin
16. Substituting a pyramidine for a pyrimadine
promoter
Which is the most and least abundant type of RNA
commaless - non - overlapping
transition
17. Hn RNA
Chediak Higashi syndrome
Translocation
Initial transcript without processing is known as
Order of mitosis
18. Less condensed - transciptionally active=eu truly transcobed
Free ribosomes
Euchromatin
GFAP
Elongation
19. Contain the actual genetic information coding for protein
Exons
Promoter mutation
Ehlers Danlos
trimethoprim
20. Unattached to any membrane; site of cytosolic and organeller prtoeins
actin and myosin
Axonemal dyenin
Free ribosomes
Exons
21. Unwinds DNA template at replication fork
helicase
Smooth ER
purines
Alternate splicing
22. Cyclin depndent kinases; consituative and inactive
microtubule
Silencer
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
CDKs
23. Hydroxy proline and hydroxylysine
Hydroxylation of which amino acids are attached to Glycine to form collagen
missense mutation
Tetracyclines
DNA/RNA/Protein syntesis direction
24. Remain in G0 regenerate from stem cells
Elongation
Mismatch repair
Glycosolation
Permanent cells
25. Substituting a purine for a pyrimdine or vice versa
Which is the most and least abundant type of RNA
transversion
What type of collagen is most affected in Ehlers Danlos
What does the hydroxylation of proline and lysine require
26. RER translation of collagen alpha chains (preprocollagen) usually Gly-X-Y
Collagedn synthesis where?
In eukaryotes the starting amino acid is...
Molecular motor protiesn
Methotrexate
27. Create a nick in the helix to relieve supercoils created during replication
intermediate filaments
DNA topoisomerases
A- T
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
28. Exocytose procollagen into extracellylar sace
Covalent alterations
Outside the cell what processing must be done in procolalgen
Free ribosomes
Excocytosis of collagen
29. Made from orogate precuror with PRPP added later
Permanent cells
Cell cycle
Which is the most and least abundant type of RNA
pyrimadines
30. CUT 1 ring Cut the Py
polyadenylation does/does not require a template
Step Three of RNA processing
Permanent cells
Pyrimidines
31. H1
Example of permanent cells
Deamination of cytosine makes
transition
The only histone not on the core
32. HS1 - HSB - H2 - H4
Clindamycin
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
Thymine has a
histone octamer names
33. The 5prime end (energy for the bond)
Introns
mRNA stop codons
Which end of the nucleotide has the triphosphate
tRNA Structure
34. Ribonucleotide reductase
Eukaroytes
6MP
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
mRNA start codons
35. Anit helminth - act on microtubules
transition
Proofreading function in eukaryotic RNA
Mebendazole/thiabendazole
Nucleotide excision repair
36. P53 and RB normally inhibit g1 to S progression
Osteogenesis Imperfecta
Tumor Suppressors
Molecular motor protiesn
Translocation
37. Responsible for the accuracy of amino acid selection
Non homologous end joining
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
DNA topoisomerases
step two of RNA processing
38. Cilia - glagella - mitotic spindle - neurons - centrioles
microtubule
desmin
Chediak Higashi syndrome
Cholchicine
39. 1P blocked by chloramphenicaol and macrolide
Translocation
Deamination of cytosine makes
Proofreading function in eukaryotic RNA
Gag on pure gold
40. Base+ribose+phosphate linked by a phosphodiester bond
transversion
Vincristine/Vinblastine
nucleotide
Replication fork
41. Prokaryotic only. Elongates leading strand by adding deoxynucleotides to the 3prime end. Elongates laggin strand. 3 prime to 5 prime exonuclease activity
Cell cycle
Molecular motor protiesn
Smooth ER
DNA pol III
42. 3 sodium out for 2 potassium in (nout - kin)takes 1 atp and the machine is phosphorylated during the machine cycle
Excocytosis of collagen
Sodium K ATPase
Nucleotide excision repair
microtubule
43. Greater melting temperature lower fluidity
Protein synthesis initiation
Plasma membrane composition
microtubule
Higher the cholesterol or long saturated fatty acid content
44. Change resulting in misreading of all nucleotides downstream - usually resulting in a truncated non functional protien
intermediate filaments
tRNA Structure
Which end of a growing DNA strand is the target
frame shift
45. Epithelial cells
cytokeratin
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
Cyclins
Cyclin - CDK
46. 75-90 nucleotides - 2ary structure cloverleaf form anticodon end is opposite 3 prime aminoacyl end
Mismatch repair
transversion
Cilia structure
tRNA Structure
47. 3 H bonds
Promoter mutation
C- G bond
intermediate filaments
Enhancers and silencer may be located_____
48. Enter G1 from G0 when stimulated Hepatocytes/lymphocytes
nonsense
Primase
Exons
Stable (quiescent)
49. Genetic code is conserved throughout evolution
Molecular motor protiesn
CDKs
Alternate splicing
universal
50. Close to - far from or even within (in an intron) the gene whose expression it regulates
Post - translational modifications
Euchromatin
Plasma membrane composition
Enhancers and silencer may be located_____