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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Proline - glycine
Cholchicine
Common amino acids in elastin
Post - translational modifications
tRNA
2. Tansport cellular cargo toward opposite ends of microtubule tracks
Glycosolation
Thymine has a
Molecular motor protiesn
Purines
3. Create a nick in the helix to relieve supercoils created during replication
Elastin is broken down by
desmin
DNA topoisomerases
Cyclin - CDK
4. 4 high enrgy bonds
Steps in splicing
Enhancer
Total energy expenditure requirement for translocation
nonsense
5. Uracil
Clindamycin
Cilia structure
Deamination of cytosine makes
Pyrimidines
6. Anti cancer - act on microtubules
Which end of the tRNA is the amino acid bound to?
Order of mitosis
intermediate filaments
Vincristine/Vinblastine
7. Bind 50S blocking translocation
Where do introns and exons stay
Macrolides
Covalent alterations
trimethoprim
8. Elastase
Elastin is broken down by
Step one of RNA processing
Cyclin - CDK
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
9. Muscle
desmin
Example of permanent cells
The only histone not on the core
Pyrimidines
10. Neurons
Neurofilaments
unambiguous
frame shift
Order of mitosis
11. Unattached to any membrane; site of cytosolic and organeller prtoeins
In eukaryotes the starting amino acid is...
Tumor Suppressors
Protein synthesis initiation
Free ribosomes
12. Anti breast cancer - acts on mts
Paclitaxil
Proofreading function in eukaryotic RNA
Glycosolation
Cell cycle
13. Inhibits the atpase which increases intracellular sodium which increases intracellular calcium increases cardiaccontractility
Digoxin (cardiac glycosides)
trimethoprim
chromatin structure
transversion
14. The 3 prime hydroxyl of the nascent chain is the target
Which end of a growing DNA strand is the target
Hydroxylation of which amino acids are attached to Glycine to form collagen
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
Enhancers and silencer may be located_____
15. Neurons - skeletal - and cardiac muscle - RBCs
Double Strand DNA repair
purines
nucleotide
Example of permanent cells
16. Bind 30S subunit preventing attachment of aminoacyl - tRNA
Methotrexate
Protein synthesis is in which direction
Tetracyclines
origin of replication
17. One codon AUG
mRNA start codons
hydroxyurea
Gag on pure gold
methionine is only encoded by
18. Immotile cilia due to a dyenin arm defect. Results in male nad female inferticility (sperm immotile) - bronchiectasis - and recurrent sinusisits - associated with situs inversus
microtubule
Kartageners syndrome
actin and myosin
Elastase is inhibited by
19. Promoter - enhancer - promoter - TATA- transcription initiation site - coding region (including exons and introns) and then the AATAAA
Xeroderma pigmentosum
Glycosolation
Initial transcript without processing is known as
Functional organization of the gene
20. HS1 - HSB - H2 - H4
Enhancer
histone octamer names
Molecular motor protiesn
GFAP
21. Each codon specifies only 1 amino acid
Tumor Suppressors
unambiguous
Protein synthesis initiation
tRNA aminoacylation
22. Cylindrical structure composed of helical array of plymerized dimers of alpha and beta tubulin - flagella - cilia - mitotic spindle - grows slowly collapses quickly
Euchromatin
microtubule
Order of mitosis
trimethoprim
23. Has enough energy to created the peptide bond
DNA pol I
Osteogenesis Imperfecta
Order of mitosis
the tRNA- amino acid bond
24. Scrutinizes aa before and after it binds to tRNA. If incorrect bond is hydrolyzed.
missense mutation
Mebendazole/thiabendazole
Aminoacylt - tRNA synthetase
frame shift
25. Methyl THYmine has a meTHYl
Pyrimidines
step two of RNA processing
Thymine has a
frame shift
26. Particular sequnece in genomre where DNA replication begins. May be single (prokaryotes) or multiple (eukaryotes)
Prokaryote RNA pol
Axonemal dyenin
origin of replication
helicase
27. Poly adenylation
Excocytosis of collagen
step two of RNA processing
tRNA activation
Termination
28. Condensed - transciptionally inactive HC- Highly condensed
Heterochromatin
Promoter mutation
tRNA Structure
Permanent cells
29. Be So Totatally Cool Read Books (bOne - CarTWOlage - Threeticular - Type IV under the floor)
actin and myosin
degenerate or redundant
aminoacyl - tRNA synthetase and binding of charged tRNA to the codon
Collagen
30. The N to C
dyenin
Labile
Protein synthesis is in which direction
Termination
31. Greater melting temperature lower fluidity
trimethoprim
Permanent cells
Tetracyclines
Higher the cholesterol or long saturated fatty acid content
32. Inhibits thymidylate synthase down thymine
5FU
Promoter mutation
Pyrimidines
Nucleotide excision repair
33. Y shaped region along DNA template where leading and lagging strands are syntehsized
Replication fork
Chloramphenicol
Initial transcript without processing is known as
Purines
34. Prokaryotic only. Degrades RNA primer and fills in the gap with DNA (5 prime to 3 prime exonuclease)
Higher the cholesterol or long saturated fatty acid content
Kartageners syndrome
DNA pol I
Introns
35. GTP
Molecular motor protiesn
Excocytosis of collagen
origin of replication
tRNA gripping and going places
36. Site where negative regulators bind
Rough ER
White codon is at the 3 prime end of a tRNA
Silencer
commaless - non - overlapping
37. Cilia - glagella - mitotic spindle - neurons - centrioles
Mismatch repair
microtubule
Aminoglycosides
Fluoroquinolones
38. Must be both activated and inactivated for cell cycle to progress
Functional organization of the gene
Cyclin - CDK
Collagen
Purines
39. Change resulting in misreading of all nucleotides downstream - usually resulting in a truncated non functional protien
Excocytosis of collagen
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
Primase
frame shift
40. Changed aaconservative - new aa is similar in chemical structure
missense mutation
Collagedn synthesis where?
6MP
Silencer
41. Base+ribose+phosphate linked by a phosphodiester bond
Step one of RNA processing
CDKs
transition
nucleotide
42. Antigout - acts on mts
Cholchicine
single stranded binding proteinds
trimethoprim
Cell cycle order
43. The 5prime end (energy for the bond)
tRNA Structure
Cyclin - CDK
Elongation
Which end of the nucleotide has the triphosphate
44. ATP- AMP (2 phosphoanhydride bonds)
Elongation
helicase
Paclitaxil
tRNA aminoacylation
45. Never go to Go divide rapidly with short G1 bone marrow - gut epithelium - skin - hair follicles
Labile
Chediak Higashi syndrome
microtubule
mRNA start codons
46. Seals
DNA ligase
Step Three of RNA processing
Purines
Cholchicine
47. ATP ase that links peripheral 9 doublets and causes bending of cilium by differential sliding of doublets
What does the hydroxylation of proline and lysine require
capped and tail transcript is called
Axonemal dyenin
purines
48. Codes for formyl methionine (f - Met)
AUG codes For what in prokaryotes
silent mutation
Prokaryote RNA pol
Paclitaxil
49. 2 H bonds greater GC content greater melting point
missense mutation
Alports syndrome
A- T
Total energy expenditure requirement for translocation
50. Site of dteroid synthesis and detoxification of druigs and poisons (liver hepatocytes and steroid horomore adrenal cortex)
Smooth ER
Stable (quiescent)
mRNA start codons
tRNA activation