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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Does not
nucleosid
polyadenylation does/does not require a template
Mebendazole/thiabendazole
cytokeratin
2. Xlinked recessive IV collagen bm - kidney - ear and eye -- nephritis and defness ocular disturbances
single stranded binding proteinds
Primase
Alports syndrome
Digoxin (cardiac glycosides)
3. Checkpoints control transition between phases of cell cycle. regulated by cyclins - CDKs and tumor suppressors. Mitosis (shortest phse)
Cell cycle
Protein synthesis is in which direction
Single Strand DNA Repair types
Xeroderma pigmentosum
4. CUT 1 ring Cut the Py
Pyrimidines
Enhancer
Associations of Ehlers Danlos
Chloramphenicol
5. Codes for formyl methionine (f - Met)
Alternate splicing
AUG codes For what in prokaryotes
Elastase is inhibited by
universal
6. Blocks denovo purine synthesis
Eukaroytes
Hereditary non polyposis colorectal cancer
desmin
6MP
7. Vimentin - desmin - cytockeratin - glial fibrillary acid proteins - neurofilaments
Gag on pure gold
DNA ligase
commaless - non - overlapping
intermediate filaments
8. 3 H bonds
Which end of the tRNA is the amino acid bound to?
C- G bond
Fluoroquinolones
Heterochromatin
9. G1 - S - G2 - Mitosis
pyrimadines
Cell cycle order
Cell cycle
Eukaroytes
10. Made from IMP precursor
purines
Termination
frame shift
the tRNA- amino acid bond
11. More than 1 codon may code for the same amino acid
Euchromatin
Plasma membrane composition
degenerate or redundant
Pyrimidines
12. Prokaryotic only. Degrades RNA primer and fills in the gap with DNA (5 prime to 3 prime exonuclease)
pyrimadines
DNA pol I
DNA ligase
In eukaryotes the starting amino acid is...
13. Antifungal - act on microtubules
Which end of the tRNA is the amino acid bound to?
Which end of a growing DNA strand is the target
Griseofulvin
Post - translational modifications
14. Inhibits the atpase which increases intracellular sodium which increases intracellular calcium increases cardiaccontractility
Immunohistochemical stains vimentin
Digoxin (cardiac glycosides)
dyenin
Clindamycin
15. The 3 prime end
Fluoroquinolones
In eukaryotes the starting amino acid is...
Which end of the tRNA is the amino acid bound to?
DNA/RNA/Protein syntesis direction
16. (A - G) 2 rings Pure As Gold
Purines
Protein synthesis initiation
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
Axonemal dyenin
17. Muscle
Labile
desmin
Smooth ER
capped and tail transcript is called
18. Binds 50S blocking translocation
Permanent cells
Tropocollagen cross links between_____ to form____
6MP
Clindamycin
19. Proline - glycine
unambiguous
Exons
The only histone not on the core
Common amino acids in elastin
20. Regulatory proteins that control cell cycle events; phase specific; activated CDKs
Immunohistochemical stains vimentin
Prokaryotes
kinesin
Cyclins
21. Anterograde to microtubule
Excocytosis of collagen
kinesin
Post - translational modifications
Replication fork
22. Genetic bone disorder (brittle bone disease) type 1 colalgen - fractures (during birth) 2) Blue sclerae 3) hearing loss 4) dental imperfections 1:10000 may be confused with child abuse
Prokaryotes
Osteogenesis Imperfecta
commaless - non - overlapping
Glycosolation
23. A site - incoming aminoacyl tRNA - Psite accomodates growing Peptide - E site holds EmplytRNA as it exits
Promoter mutation
Going APE
Smooth ER
The only histone not on the core
24. Inhibits dihydrofolate reductase down thymine
Elastin is broken down by
Hereditary non polyposis colorectal cancer
Methotrexate
Replication fork
25. Neurons
nucleosid
What type of collagen is most affected in Ehlers Danlos
Neurofilaments
Exons
26. Antigout - acts on mts
Cholchicine
Hereditary non polyposis colorectal cancer
Double Strand DNA repair
What does the hydroxylation of proline and lysine require
27. Alpha 1 antitrypisn
Elastase is inhibited by
Chloramphenicol
Purines
Translocation
28. Bm - kidney - ears and eyes
Type IV collagen is an important structural component of...
Gag on pure gold
RNA processing in eukaryotes occurs
Enhancer
29. Less condensed - transciptionally active=eu truly transcobed
Loading tRNA on to ribosome energy requirement
Step Three of RNA processing
Euchromatin
Axonemal dyenin
30. Ribonucleotide reductase
CDKs
Collagedn synthesis where?
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
Type IV collagen is an important structural component of...
31. 1P blocked by chloramphenicaol and macrolide
nucleotide
Clindamycin
Translocation
Example of permanent cells
32. The 3 prime hydroxyl of the nascent chain is the target
Which end of a growing DNA strand is the target
nonsense
Elongation
degenerate or redundant
33. Anti cancer - act on microtubules
White codon is at the 3 prime end of a tRNA
Vincristine/Vinblastine
tRNA activation
Collagen
34. Aminoacyl - tRNA binds to A site 2) peptidyltransferase catalyzes peptide bond formation transfers growing polypeptie to amino acid in A site 3) ribosome advances 3 nucleotides toward the 3 prime end of RNA moving peptiydyl RNA to P site
tRNA gripping and going places
Step Three of RNA processing
What type of collagen is most affected in Ehlers Danlos
Elongation
35. Different exons can be combined to make nique protiens in different times
Alternate splicing
DNA pol I
step two of RNA processing
6MP
36. Has enough energy to created the peptide bond
microtubule
universal
the tRNA- amino acid bond
Which end of a growing DNA strand is the target
37. VItamin C
Which end of the nucleotide has the triphosphate
What does the hydroxylation of proline and lysine require
Elastin is broken down by
Rough ER
38. Unmethylated - newly synthesized string is recognized - mismatched nucleotides are removed and the gap is filled and resealed
Mismatch repair
commaless - non - overlapping
frame shift
Proteosomal degradation
39. Strethchy protein within lungs - large artiers - elastic liaments - vocal cords - ligamenta flava)
Cholchicine
Covalent alterations
Elastin
Oubain
40. Type III
Vincristine/Vinblastine
Tropocollagen cross links between_____ to form____
What type of collagen is most affected in Ehlers Danlos
Higher the cholesterol or long saturated fatty acid content
41. The N to C
What type of collagen is most affected in Ehlers Danlos
Aminoacylt - tRNA synthetase
DNA pol III
Protein synthesis is in which direction
42. Commonly results in dramatic decrease in amount of gene transcribed
Alports syndrome
Exons
Promoter mutation
Cyclins
43. Particular sequnece in genomre where DNA replication begins. May be single (prokaryotes) or multiple (eukaryotes)
origin of replication
tRNA Structure
Primase
5FU
44. No proofreading function but can initiate chains. RNA poymerase II opens DNA at promoter site
Proofreading function in eukaryotic RNA
Cell cycle
Where do introns and exons stay
Macrolides
45. Bind 50S blocking translocation
C- G bond
Macrolides
Aminoacylt - tRNA synthetase
Protein synthesis initiation
46. Stretch of DNA that alters gene expression by binding transcription factors
Steps in splicing
Heterochromatin
Hydroxylation of which amino acids are attached to Glycine to form collagen
Enhancer
47. Bind 30S subunit preventing attachment of aminoacyl - tRNA
Nucleotide excision repair
Molecular motor protiesn
Kartageners syndrome
Tetracyclines
48. Substituting a purine for a pyrimdine or vice versa
tRNA Structure
Protein synthesis initiation
Going APE
transversion
49. 1 RNA polymerase (multisubunite complex) makes all 3 kinds of RNA
White codon is at the 3 prime end of a tRNA
pyrimadines
Protein synthesis initiation
Prokaryote RNA pol
50. UGA - UAG - UAA
Macrolides
Guanine has a
Purines
mRNA stop codons