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First Aid: Biochemistry Molecular

Instructions:
  • Answer 50 questions in 15 minutes.
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  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Odd 30S plus 50 S=70S






2. Xlinked recessive IV collagen bm - kidney - ear and eye -- nephritis and defness ocular disturbances






3. Inhibits dihydrofolate reductase down thymine






4. HS1 - HSB - H2 - H4






5. Prokaryotic only. Degrades RNA primer and fills in the gap with DNA (5 prime to 3 prime exonuclease)






6. Checkpoints control transition between phases of cell cycle. regulated by cyclins - CDKs and tumor suppressors. Mitosis (shortest phse)






7. Specific glycosylases recognize and remove damaged bases - AP endonuclease cuts DNA at pyrimidne site - empty sugar is removed and the gap is filled and resealed






8. ATP ase that links peripheral 9 doublets and causes bending of cilium by differential sliding of doublets






9. Each codon specifies only 1 amino acid






10. Made from orogate precuror with PRPP added later






11. Bind 50S blocking translocation






12. 1) primary transcript combines with snRNPs and other proteins to form spliceosome 2) lariat shaped intermediate is generated 3) Lariat is removed and released to precisely join 2 exons






13. Trimming removal of n or c terminal propeptides from zymogens to generate mature proteinds






14. Inhibits bacterials dihydrofolate reducatese down thymine






15. Anit helminth - act on microtubules






16. Epithelial cells






17. Bind 30S subunit preventing attachment of aminoacyl - tRNA






18. 5 prime to 3 prime






19. Even 40S 60S =80S






20. Three amino acids necessary for purine synthesis= glutamine - aspartate and glycine






21. Phosphorylation - glycosloation - hyderoxylation






22. Cilia - glagella - mitotic spindle - neurons - centrioles






23. H1






24. Bm - kidney - ears and eyes






25. Close to - far from or even within (in an intron) the gene whose expression it regulates






26. Change resulting in misreading of all nucleotides downstream - usually resulting in a truncated non functional protien






27. Type III






28. Regulatory proteins that control cell cycle events; phase specific; activated CDKs






29. Asymmetric fluid bilayer - contains - cholesterol - phospholipids - sphingoplipids - glycolipids - and protiends






30. Neurons






31. Nucleotide excision repair - Base Excision repair - Mismath repair






32. G1 - S - G2 - Mitosis






33. Cyclin depndent kinases; consituative and inactive






34. Y shaped region along DNA template where leading and lagging strands are syntehsized






35. (A - G) 2 rings Pure As Gold






36. Rampant - Massive - TIny rRNA is most common - then mRNA and then tRNA






37. Codes for formyl methionine (f - Met)






38. Anti breast cancer - acts on mts






39. Made from IMP precursor






40. Must be both activated and inactivated for cell cycle to progress






41. Inhibits ribonucleotide reductase






42. Immotile cilia due to a dyenin arm defect. Results in male nad female inferticility (sperm immotile) - bronchiectasis - and recurrent sinusisits - associated with situs inversus






43. 3 sodium out for 2 potassium in (nout - kin)takes 1 atp and the machine is phosphorylated during the machine cycle






44. Scrutinizes aa before and after it binds to tRNA. If incorrect bond is hydrolyzed.






45. Brings together 2 ends of DNA fragments no requirement for homology






46. 1P blocked by chloramphenicaol and macrolide






47. A site - incoming aminoacyl tRNA - Psite accomodates growing Peptide - E site holds EmplytRNA as it exits






48. Read froma fixed starting point as a continous sequenecs of bases






49. Exocytose procollagen into extracellylar sace






50. 75-90 nucleotides - 2ary structure cloverleaf form anticodon end is opposite 3 prime aminoacyl end







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