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Test your basic knowledge |
First Aid: Biochemistry Molecular
Start Test
Study First
Subjects
:
health-sciences
,
first-aid
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. No proofreading function but can initiate chains. RNA poymerase II opens DNA at promoter site
universal
Proofreading function in eukaryotic RNA
mRNA stop codons
Which end of the tRNA is the amino acid bound to?
2. Methyl THYmine has a meTHYl
Initial transcript without processing is known as
A- T
Ribonucleotides are synthesized first and convertec to deoxyribonuclotides by
Thymine has a
3. Odd 30S plus 50 S=70S
Prokaryotes
Associations of Ehlers Danlos
Mismatch repair
Covalent alterations
4. Asymmetric fluid bilayer - contains - cholesterol - phospholipids - sphingoplipids - glycolipids - and protiends
frame shift
DNA pol III
Plasma membrane composition
Protein synthesis initiation
5. Checkpoints control transition between phases of cell cycle. regulated by cyclins - CDKs and tumor suppressors. Mitosis (shortest phse)
Axonemal dyenin
Cell cycle
Glycosolation
Tropocollagen cross links between_____ to form____
6. Hn RNA
Termination
degenerate or redundant
Initial transcript without processing is known as
What type of collagen is most affected in Ehlers Danlos
7. Enter G1 from G0 when stimulated Hepatocytes/lymphocytes
5FU
Cell cycle order
Enhancer
Stable (quiescent)
8. 1P (blocked by tetracycline)
tRNA
Osteogenesis Imperfecta
DNA pol III
Loading tRNA on to ribosome energy requirement
9. Prokaryotic only. Degrades RNA primer and fills in the gap with DNA (5 prime to 3 prime exonuclease)
Translocation
DNA pol I
Xeroderma pigmentosum
mRNA stop codons
10. Site of dteroid synthesis and detoxification of druigs and poisons (liver hepatocytes and steroid horomore adrenal cortex)
mRNA start codons
Pyrimidines
frame shift
Smooth ER
11. Has enough energy to created the peptide bond
Protein synthesis is in which direction
the tRNA- amino acid bond
Griseofulvin
dyenin
12. Microtubule polymerization defect resulting in lowered phagocytosis. results in recurrent pyogenic infections - partial albinism and peripheral neuropathy
Paclitaxil
Chediak Higashi syndrome
Translocation
Tetracyclines
13. The 3 prime hydroxyl of the nascent chain is the target
White codon is at the 3 prime end of a tRNA
Which end of a growing DNA strand is the target
purines
Cyclins
14. CUT 1 ring Cut the Py
Cyclin - CDK
Protein synthesis is in which direction
Pyrimidines
White codon is at the 3 prime end of a tRNA
15. Specific endonucleases release the oligonucleotide containing damaged bases. DNA polymerase and logase fill and resealt eh gap
missense mutation
Loading tRNA on to ribosome energy requirement
Nucleotide excision repair
single stranded binding proteinds
16. Unwinds DNA template at replication fork
Neurofilaments
Clindamycin
intermediate filaments
helicase
17. Accurate base pairing is required only in the first 2 nucleotide positions of an mRNA so codons differing ht e3rd wobble psoition may code for the same tRNA/amino acid code
origin of replication
Heterochromatin
tRNA
Enhancer
18. 75-90 nucleotides - 2ary structure cloverleaf form anticodon end is opposite 3 prime aminoacyl end
transversion
Glycosolation
microtubule
tRNA Structure
19. Inhibits thymidylate synthase down thymine
5FU
transversion
Proteosomal degradation
Example of permanent cells
20. Epithelial cells
cytokeratin
tRNA gripping and going places
Paclitaxil
step two of RNA processing
21. Blocks denovo purine synthesis
tRNA aminoacylation
Excocytosis of collagen
nucleotide
6MP
22. In the nucleus after transcitpion and only processed RNA is transporte out of the nucleus
6MP
pyrimadines
RNA processing in eukaryotes occurs
intermediate filaments
23. Be So Totatally Cool Read Books (bOne - CarTWOlage - Threeticular - Type IV under the floor)
step two of RNA processing
Euchromatin
alpha amintin
Collagen
24. Inhibits dihydrofolate reductase down thymine
Replication fork
promoter
Type IV collagen is an important structural component of...
Methotrexate
25. 5 prime to 3 prime
Glycosolation
trimethoprim
Rough ER
mRNA is syntehsized in which direction?
26. Inhibit DNA gyrase (specific prokaryotic topoisomerase)
step two of RNA processing
Digoxin (cardiac glycosides)
actin and myosin
Fluoroquinolones
27. Regulatory proteins that control cell cycle events; phase specific; activated CDKs
Cyclins
tRNA Structure
Elastin
5FU
28. Close to - far from or even within (in an intron) the gene whose expression it regulates
Proofreading function in eukaryotic RNA
Enhancers and silencer may be located_____
Cilia structure
Example of permanent cells
29. Immotile cilia due to a dyenin arm defect. Results in male nad female inferticility (sperm immotile) - bronchiectasis - and recurrent sinusisits - associated with situs inversus
microtubule
Kartageners syndrome
Covalent alterations
DNA ligase
30. A malfunction of mismatch repair (MUt L etc..)
Clindamycin
desmin
Hereditary non polyposis colorectal cancer
microtubule
31. One codon AUG
Collagen
Eukaroytes
step two of RNA processing
methionine is only encoded by
32. ATP- AMP (2 phosphoanhydride bonds)
Tropocollagen cross links between_____ to form____
Which end of the tRNA is the amino acid bound to?
tRNA aminoacylation
Glycosolation
33. Trimming removal of n or c terminal propeptides from zymogens to generate mature proteinds
Post - translational modifications
Loading tRNA on to ribosome energy requirement
AUG codes For what in prokaryotes
Osteogenesis Imperfecta
34. Inhibits ribonucleotide reductase
Tropocollagen cross links between_____ to form____
hydroxyurea
Which end of the nucleotide has the triphosphate
Guanine has a
35. Introns stay In the nucleus whereas EXons EXit and are EXpressed
Proofreading function in eukaryotic RNA
Where do introns and exons stay
microtubule
nucleosid
36. Base + ribose
purines
White codon is at the 3 prime end of a tRNA
nucleosid
Pyrimidines
37. Genetic bone disorder (brittle bone disease) type 1 colalgen - fractures (during birth) 2) Blue sclerae 3) hearing loss 4) dental imperfections 1:10000 may be confused with child abuse
The only histone not on the core
Osteogenesis Imperfecta
Neurofilaments
Cyclin - CDK
38. Scrutinizes aa before and after it binds to tRNA. If incorrect bond is hydrolyzed.
Double Strand DNA repair
Nucleotide excision repair
Aminoacylt - tRNA synthetase
Heterochromatin
39. HS1 - HSB - H2 - H4
Prokaryote RNA pol
pyrimadines
AUG codes For what in prokaryotes
histone octamer names
40. Site of secretory protiens (mucus secreting goblet cells and antibody secreting cells)
Purines
Rough ER
Elastase is inhibited by
hydroxyurea
41. RER translation of collagen alpha chains (preprocollagen) usually Gly-X-Y
Guanine has a
DNA/RNA/Protein syntesis direction
Example of permanent cells
Collagedn synthesis where?
42. Inhbits RNA pol II (found in death cap mushrooms)
Tumor Suppressors
Outside the cell what processing must be done in procolalgen
AUG codes For what in prokaryotes
alpha amintin
43. Must be both activated and inactivated for cell cycle to progress
Cyclin - CDK
Hydroxylation of which amino acids are attached to Glycine to form collagen
Mebendazole/thiabendazole
DNA/RNA/Protein syntesis direction
44. Cilia - glagella - mitotic spindle - neurons - centrioles
Protein synthesis initiation
C- G bond
microtubule
alpha amintin
45. Mutation in nucleotide excision repair Dry skin with melanoma and other cancers
Promoter mutation
DNA pol I
Xeroderma pigmentosum
transversion
46. Ketone
trimethoprim
Single Strand DNA Repair types
Guanine has a
Which end of the nucleotide has the triphosphate
47. The 3 prime end
Which end of the tRNA is the amino acid bound to?
Cilia structure
Non homologous end joining
Immunohistochemical stains vimentin
48. Makes an RNA primer on which DNA polymerase II can initiate replication
Prokaryotes
Prokaryote RNA pol
Primase
histone octamer names
49. Inhibit formation of the initation complex and cause misreading of mRNA
Griseofulvin
Aminoglycosides
Promoter mutation
Protein synthesis initiation
50. Antigout - acts on mts
Cholchicine
nucleotide
trimethoprim
White codon is at the 3 prime end of a tRNA