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First Aid: Reproductive

Subjects : health-sciences, first-aid

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Answer 50 questions in 15 minutes.
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1. What is associated with sclerosing adenosis?
Calcifications
Inhibit cGMP breakdown
Testosterone
Chromosomal abnormalities

2. What is HELLP syndrome
Choriocarcinoma
Whorled pattern of smooth muscle bundles
Hemolysis - elevated liver enzymes - low platelets
E coli

3. What does hCG do in the first trimester to maintain the corpus luteum
Oligomenorrhea
Mimics LH
Placental insufficiency - bilateral renal agenesis - posterior urethral valves - potter's syndrome
Decreasing progesterone

4. What does estrogen do to FSH and LH
Upregulation - LH surge - ovulation
Peripheral conversion of androgens
Testis determining factor
Feedback inhibition

5. cystic swelling of chorionic villi and proliferation of chorionic epithelium that presents with abnormal vaginal bleeding
Hydatidiform mole
Axillary node involvement
Osteoblastic in bone
Placenta acreta

6. What is the right venous drainage of the ovary/testis
Call exner bodies
Right gonadal vein - IVC
HPV 16 - 18
Fibroadenoma

7. What are the most common cause of anovluation

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8. Where is testosterone converted to estrogen
Cardinal ligament
Sertoli cells - and adipose tissue via aromatase
PCOS
Embryonal carcinoma

9. What are common causes of hyperestrogenism

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10. hyperandrogenism due to deranged steroid synthesis by theca cells - increased LH leading to anovulation
PCOS
17beta estradiol
Down regulation
Induces and maintains lactation - decreases reproductive function

11. Complication of retained placental tissue
The centrioles
Left gonadal vein - left renal vein - IVC
Polyhydramnios
Hemorrhage

12. From What tissues to malignant breast tumors arise?
Stimulates testosterone release from leydig cells
Ectocervix
Mammary duct epithelium or lobular glands
Mature teratoma

13. What is the lymphatic drainage of the proximal 2/3 of the vagina/uterus
Intraductal papilloma
Preeclampsia + siezures
Milk letdown - uterine contractions?
Obdurator - exterinal iliac - hypogastic nodes

14. What are the treatments for PCOS
17beta estradiol
Erythroplasia of Queyrat - carcinoma in situ of penis
Weight loss - OCP - gonadotropin analogs - clomiphene - sprinolactone - surgery
Hydatidiform mole

15. What does progesterone do to body temp
Obdurator - exterinal iliac - hypogastic nodes
Proliferation
Increase
Endocervix

16. How is beta hCG detectable in blood or urine for a home pregnancy test
1 week - 2 weeks
Syncytiotrophoblasts of placenta
Leydig cell tumor
Fibroadenoma - phyllodes tumor

17. Endometriosis is characterized By what clinical picture?
Retrograde mentrual flow or ascending infection
Cyclic bleeding - chocolate cysts - severe menstrual related pain - infertility
Neoplastic cells block lymphatic drainage
Immature

18. When is follicular growth the fastest?
Stimulates testosterone release from leydig cells
51 yo
The centrioles
2nd week of proliferative phase

19. What is the expected increase of estradiol and estrone in pregnancy
Yolk sace - endodermal sinus - tumor
Kallman
51 yo
50 times

20. What is a true hermaphrodite
Both ovary and testicular tissue present - ambiguous genitals - rare 46 XX - 47XXY
Placental insufficiency - bilateral renal agenesis - posterior urethral valves - potter's syndrome
No
No

21. List the estrogens in order of decreasing potency
Estradiol > estrone > estriol
Menometrorrhagia
Choriocarcinoma
CIN 1 - 2 - 3

22. defect in androgen receptor resulting in normal appearing female - rudimentry vagina - no uterus or uterine tubes
One of the centrioles
Androgen insensitivity syndrome - 46 XY
Corpus luteum - placenta - adrenal cortex - testes
Erythroplasia of Queyrat - carcinoma in situ of penis

23. Which cells line the seminiferous tubules and maintain germ pool and produce primary spermatocytes
Chromosomal abnormalities
Paget's disease - breast abscess
Spermatogonia (germ cells)
Mammary duct epithelium or lobular glands

24. What percentage of testicular tumors are germ cell
50 times
Invasive lobular
95%
Sertoli cells

25. What is the most common form of male pseudoHerm
Androgen insensitivity syndrome
CIN 1 - 2 - 3
Adolescents
Tunica vaginalis lesions

26. leiomyoma and leiosarcoma have an increased incidence in which ethnic group
DHT - testosterone - androstenedione
Post menopausal
Seminoma
Blacks

27. What hormones regulate sperm creation?
Final stage of spermatogenesis - spermiogenesis - spermatid to spermatozoa
GnRH from hypoTh - LH and FSH from ant pituitary
Complete
Placenta acreta

28. Which cells line the seminiferous tubules and secrete inhibin
The ampulla - occurs within 1 day of ovulation
Sertoli cells
Down regulation
Mimics LH

29. When does endometiral carcinoma usually occur
55-65
Calcifications
Golgi
Upregulation

30. What increase in estriol is an indicator offetal well being in pregnancy
increased risk for carcinoma
Testosterone
1000 times
Yolk sac - endodermal sinus - tumor

31. What forms the blood testis barrier?
The semiT and the blood vessels
Osteoblastic in bone
Tight junctions between sertoli cells
Prophase

32. common cause of recurrent miscarriage in 1st trimester
Stimulates sertoli cells to produce ABP and inhibin
Cerebral hemorrhage and ARDS
S aureus
Chromosomal abnormalities

33. What bacteria is commone in acute prostatitis
Increase in size in pregs - decrease in size meno - estrogen sens
Estradiol
increased estrogen - increased total nunmber of cycles - older age at 1st live birth - obesity
E coli

34. tumor that fills ductal lumen - arises from ductal hyperplasia - early malignancy without BM penetration
Anovulatory cycles - hormone replacement therapy - PCOS - granulosa cell tumor
Intraductal papilloma
DCIS
Just prior to ovulation

35. Which phase varies and in length and Which is usually 14 days (menstrual cycle)
Follicular phase varies - luteal phase is 14
increased size and tenderness with increased estrogen
Decreasing progesterone
Round ligament of uterus

36. histologic subtype of fibrocystic with increased acini and intralobular fibrosis
69 xxy
Abacterial
Round ligament of the uterus
Sclerosing adenosis

37. Red velvety plaques - usually involving the glans - similar to Bowen's
Dysuria - frequency - urgency - low back pain
5 alpha reductase def
Erythroplasia of Queyrat - carcinoma in situ of penis
Low back pain with increased serum alk phos

38. testicular masses that can be transilluminated
Prior c section - multiparity
Tunica vaginalis lesions
Squamous cell carcinoma
Post menopausal

39. Prevention of seizures and in preeclampsia
Prostate growth - balding - and sebaceous gland activity
IV mag sulfate - diazepam
Ligament of the ovary
Serous cystadenocarcinoma

40. testes present with non male external genitals
CIN 1 - 2 - 3
DIC
Male pseudoHerm
Acute mastitis

41. What is the clinical manifestation of PCOS
Dysuria - frequency - urgency - low back pain
S aureus
Enlarged bilateral cystic ovaries - amenorrhea - infertility - obesity - and hirsutism
Just prior to ovulation

42. malignant - increased hCG - disordered syncytiotrophoblastic and cytotrophoblastic elements - hematogenous spread
Choriocarcinoma
The ampulla - occurs within 1 day of ovulation
Testosterone - DHT - androstenedione
Preeclampsia clinical

43. Breast path - diseeases of the lobules
Increase
Mucinous cystadenocarcinoma
Sertoli cells - and adipose tissue via aromatase
Lobular carcinoma - sclerosing adenosis

44. can present as precocious puberty in kids - can cause endometrial hyperplasia/carinoma in adults - abnormal uterine bleeding
Testosterone
Granulosa cell tumor
Theca - leutin cysts
Menometrorrhagia

45. What is a complication of invasive carcinoma
Lateral invasion can block ureters causing renal failure
During fetal life
Prostate growth - balding - and sebaceous gland activity
Esophogeal/duodenal atresia - can't swallow - anencephaly

46. A leimyoma is overgrowth of what cell
Krukenburg tumor
Cirrhosis - testicular tumor - puberty - old age - klinefelter's syndrome - drugs
Lack of spermatogenesis due to increased temp of testis inside body and associated risk of germ cell tumors
Smooth muscle

47. How many functional sperm does 1 germ cell creat?
Choriocarcinoma
Metrorrhagia
4
Multiple sexual partners - also HIV and early sexual intercourse

48. Breast path - diseases of the terminal duct
Right gonadal vein - IVC
No
Tubular carcinoma
Alpha1 antagonists - terazosin - tamsulosin - finasteride

49. Which gynecologic tumors have the worst prognosis?
Testosterone
The anterior pituitary and hypothalamus
Kallman
Ovarian > cervical > endometrial

50. What causes preeclampsia
Brenner tumor
Placental ischemia due to impaired vasodltn of spiral arteries resulting in increased vasc tone
69 xxy
Both ovary and testicular tissue present - ambiguous genitals - rare 46 XX - 47XXY

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First Aid: Reproductive

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