SUBJECTS
|
BROWSE
|
CAREER CENTER
|
POPULAR
|
JOIN
|
LOGIN
Business Skills
|
Soft Skills
|
Basic Literacy
|
Certifications
About
|
Help
|
Privacy
|
Terms
|
Email
Search
Test your basic knowledge |
Hemeonc
Start Test
Study First
Subject
:
health-sciences
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What is the defect in beta thal?
Extrinsic - I - II - V - VII and X
EBV
CML to AML or All
Splicing sites and promotor sequences
2. What do the dense granules contain in platelets
Pyruvate kinase def - extravascular
ADP and Ca
Antigen - antibody
5- FU - AZT - hydroxyurea
3. What causes the physiologic chloride shift and What does the chloride shift do?
Produce antibody - lots of RER and golgi
Inc serum iron - normal TIBC - inc ferratin
Chloride bicarb antiport system - - allows transport of C02 from periph to lungs
PGI2 - NO inc blood flow - dec platelet aggregation
4. Impaired synthesis of DAF leading to inc complement mediated desctruction of RBCs via the GPI ancho
Paroxysmal nocturnal hemoglobinuria
All
Mycosis fundgoides/Sezary syndrome
Deoxygenated HbS polymerizes - low O2 or dehydration precipiates sickling - anemia and veno - occlusive disease
5. Which drugs can cause macrocytic anemia?
Sheets of lymphocytes interspersed with macs
Paroxysmal nocturnal hemoglobinuria
MHC II and Fc receptors
5- FU - AZT - hydroxyurea
6. Defect in platelet to collagen adhesion - receptor - disorder - platelet count and BT
Gp1b - bernard - soulier - dec platelets (giant platelets not counted) - inc BT
Macrohemorrhage - hemarthroses - easy bruising
Acts to stabilize platelet plug
Factor V resistant to activated protein C's inhibition
7. anti - GpIIb/IIIa antibodies leading to peripheral platelet destruction
Round densly staining nucleus with a small amount of pale cytoplasm
Intravascular hemolysis
Petechiae
Idiopathic thrombocytopenia (ITP)
8. Blood type B
Decrease EPO
Eleveated PT - PTT
B antigena and A antibodes
Epoxide reductase - warfarin inhibits
9. fatigue - malaise - pallor - purpura - mucosal bleeding - petechiae - infection
Signs and sx of aplastic anemia
Beta chain underproduced - asymptomatic - heterozygote
Marrow - marrow - follicles of lymph nodes - white pulp of spleen (unencapsulated lymphoid tissue)
A antigen and B antibodies
10. What is the characteristic spread of Hodgkin Lymphoma
Contiguous
Liver disease - abetalipoproteinemia - acntho = spiny
Complications of sickle cell anemia
Nl PT - elevated PTT - intrinsic pathway defect
11. What does bradykinin do?
Lead poisoning - rRNA causes aggregration of ribosomes and basophilic stippling
Inc vasodiltion - inc perm - inc pain
Inc HbF and dec HbS
MHC II and Fc receptors
12. What is the characteristic lab finding on electrophoresis
Paraprotein spike - monoclonal protein
Lymphoma
Inc suscept to infxn - primary amyloidosis - punched out lytic bone lesions - M spike - Ig light chains in urine - Rouleaud formations (stacked RBCs)
Hereditary elloptocytosis
13. What are the two substances produced by eosinophils help limit the reaction following mast cell degranulation?
No antigen - both antibodies
Histaminase and arylsulfatase
Beta 4
Protoporphyrin
14. What activates the fibrinolytic pathway?
Inc UCB
Birbeck granules
XIIa activates kallikrein - which activates plasmin (and converts HMWK to bradykinin
Inc HbA2 on electrophoresis
15. What does ectopic EPO produce
Inappropriate absolute with inc RBCs and EPO
Alpha thal - asian and african american
20 to 40
Bernard soulier
16. drug that inhibits ADP induced expression of GpIIb/IIIa
Folate def
Ticlopidine/clopidogrel
Up - down - up
Up - down - nl
17. discrete tumor masses arising from lymph nodes
Bone marrow infiltration - myelofibrosis
Lymphoma
Kidney - Gi - microcytic anemai in both - kids = mental retardation and adults = headache - memory loss - demyelination
Eleveated PT - PTT
18. CD5+ - poor prognosis - t(11;14)
Bite cells and Heinz bodies
Mantle cell - older males
Down - down - up
Varying shapes
19. t(11:22)
Ewing sarcoma
Up - down - nl
Defect in 4 - not compatible with life - defect in 3 - HbH disease - defect in 1/2 not associated with sig anemia
Induces differentiation of myeloblasts
20. What is the effect of ACE on bradykinin
Inactivates it
Hairy cell leukemia
Lysine for glutamate at position 6
Inc suscept to infxn - primary amyloidosis - punched out lytic bone lesions - M spike - Ig light chains in urine - Rouleaud formations (stacked RBCs)
21. tennis rackets on EM
Birbeck granules
Beta thal
Polycythemia vera with inc plasma volume - inc RBCs - inc EPO
Deoxygenated HbS polymerizes - low O2 or dehydration precipiates sickling - anemia and veno - occlusive disease
22. Which infections can cause MAHA?
Malaria - Babesia
Hairy cell leukemia
Bernard soulier
Schistocytes - helmet cells
23. Why does B12 def cause neuro sx?
Positive osmootic fragility test and splenectomy
DDAVP (desmopressin) which releases stored vWF stored in endothelium
B12 in fatty acid pathways leads to subacute combined degeneration
Valine for glutamate
24. What is the therapy for the M3 variant?
Erythroblastosis fetalis - Rh or other blood antigen incompatibility
Acts to stabilize platelet plug
All trans retinoic acid
Tissue
25. What is the coombs test results in AIHA?
Factor V resistant to activated protein C's inhibition
Pos
Varying sizes
Macrohemorrhage - hemarthroses - easy bruising
26. What does ADP do?
Porphobilinogen - delta ALA - uroporphyrin
B6 therapy (pyrodixine)
Erythroblastosis fetalis - Rh or other blood antigen incompatibility
Helps platelts adhere to endothelium
27. What do you see in vit K def
1 to 6
Eleveated PT - PTT
Kids= exposure to lead paint - adults = battery - ammunition factory
No lytic bone lesions in WM
28. What does NAACP stand for - in regards to the causes of eosinophiia?
Yes - via MHC II
Leukemia
Pos
Neoplastic - asthma - allergic processes - collagen vacsular disease - parasites
29. What are dendritic cells called in the skin?
Hemolytic or non hemolytic - and then for the hemolytiuc - intravascular hemolysis or extravascular hemolysis
Langerhans cells
Lysine for glutamate at position 6
Porphobilinogen deaminase aka uroporphyrinogen I synthase
30. What is the affected enzyme in acute intermittment porphyria
Porphobilinogen - delta ALA - uroporphyrin
Acts to stabilize platelet plug
B12/folate def
DIC - TTP/HUS - traumatic hemolysis
31. What is the are the presenting symptoms of lead poisoning in kids and adults
XIIa activates kallikrein - which activates plasmin (and converts HMWK to bradykinin
Aspirin
Kidney - Gi - microcytic anemai in both - kids = mental retardation and adults = headache - memory loss - demyelination
Inc large vWF multimers - inc platelet aggregation and thrombosis
32. What do the labs show for TTP?
Schistocytes and inc LDH
Deoxygenated HbS polymerizes - low O2 or dehydration precipiates sickling - anemia and veno - occlusive disease
Hairy cell leukemia
Protoporphyrin (blood)
33. Serum iron - transferrin - ferritin lab values for iron def anemia
Bite cells and Heinz bodies
TRAP (tartrate resistant acid phosphatase
Down - up - down
Parvovirus
34. HTLV-1
Leukemia
Adult T cell lymphoma - presents with cutaneous lesions
Easy gas exchange
Low O2 in papilla; can also get microhematuria from medullary infarcts
35. Sickle cell
SLE - CLL - alpha methyldopa
Mycosis fundgoides/Sezary syndrome
Sickle cell anemia
EBV
36. What do you see a starry sky appearance in Burkitt
Sheets of lymphocytes interspersed with macs
PGI2 - NO inc blood flow - dec platelet aggregation
Induces differentiation of myeloblasts
Polycythemia vera with inc plasma volume - inc RBCs - inc EPO
37. How do platelet disorders present?
Inc bleeding time - microhemorrhage: mucuous membrane bleeding - epitaxis - petechiae - purpura - possible thrombocytopenia
Ringed sideronblasts with iron laden mitochondria
Multiple - peripheral nodes - extranodal involvement - noncontiguous spread
XIIa activates kallikrein - which activates plasmin (and converts HMWK to bradykinin
38. Deficiency in GpIIb/IIIa
Warning
: Invalid argument supplied for foreach() in
/var/www/html/basicversity.com/show_quiz.php
on line
183
39. Plasma cell neoplasm
B cells
Bite cells and Heinz bodies
Multiple myeloma
ADP and Ca
40. Back pain - hemoglobinuria
Aspirin
Common a few days after oxidative stress in a pt with G6PD
AML
Lacunar in nodular sclerosing variant
41. Upregulated growth of leukocytes in bone marro
Fibrinogen bind GpIIb/IIIa and links platelts
Schistocytes and inc LDH
IgG - Warm is GREAT
Leukemia
42. What vitamin is a cofactor for the first step of heme synthesis
Contiguous
B6
Abciximab
Langerhans cell histiocytosis
43. What is the activation stage of platelet plug formation?
Hairy cell leukemia
CLL (SLL without the peripheral lymphocytosis
PENTAD: neurologic sx - renal sx - fever - thrombocytopenia - MAHA
ADP binding to receptors causes upregulation of GpIIb/IIIa expression at platelet surface
44. can be asymptomatic - often in older adults - peripheral blood lymphcytosis with smudge cells and warm antibody autoimmune hemolytic anemia
Degrades fibrin mesh and converts C3 to C3a
Exposed collagen upon endothelial damage
CLL (SLL without the peripheral lymphocytosis
Schistocytes and inc LDH
45. What are the age ranges for the various leukemias
All < 15 - AML = median onset around 60 - CML = 30 to 60 - and CLL > 60
Birbeck granules
Chloride bicarb antiport system - - allows transport of C02 from periph to lungs
Induces differentiation of myeloblasts
46. Causes of iron def?
Glanzmann's throbmasthenia - GpIIb/IIIa - nl platelets - inc BT
Bleeding - malnutrition/absorption - inc demand pregs
DNA synth impaired - maturation of nucleus delayed relative to maturation of cytoplasm
Alpha thal - asian and african american
47. What symptoms are associated with Hodgkin lymphoma
IFN gama
Schistocytes and inc LDH
DNA synth impaired - maturation of nucleus delayed relative to maturation of cytoplasm
B symptoms - fever night sweats - weight loss
48. What is the general pathology of a macrocytic anemia?
Bimodal - men>women - except for nodular sclerosing type
DNA synth impaired - maturation of nucleus delayed relative to maturation of cytoplasm
Helps platelts adhere to endothelium
Intravascular
49. poikilocytosis
Bone marrow infiltration - myelofibrosis
ATIII def
Varying shapes
Low in CML
50. Which maternal antibodies cross the placenta - anti A/B or anti Rh
Anti Rh
Prothrombin gene mutation
Birbeck granules
All < 15 - AML = median onset around 60 - CML = 30 to 60 - and CLL > 60
Sorry!:) No result found.
Can you answer 50 questions in 15 minutes?
Let me suggest you:
Browse all subjects
Browse all tests
Most popular tests
Major Subjects
Tests & Exams
AP
CLEP
DSST
GRE
SAT
GMAT
Certifications
CISSP go to https://www.isc2.org/
PMP
ITIL
RHCE
MCTS
More...
IT Skills
Android Programming
Data Modeling
Objective C Programming
Basic Python Programming
Adobe Illustrator
More...
Business Skills
Advertising Techniques
Business Accounting Basics
Business Strategy
Human Resource Management
Marketing Basics
More...
Soft Skills
Body Language
People Skills
Public Speaking
Persuasion
Job Hunting And Resumes
More...
Vocabulary
GRE Vocab
SAT Vocab
TOEFL Essential Vocab
Basic English Words For All
Global Words You Should Know
Business English
More...
Languages
AP German Vocab
AP Latin Vocab
SAT Subject Test: French
Italian Survival
Norwegian Survival
More...
Engineering
Audio Engineering
Computer Science Engineering
Aerospace Engineering
Chemical Engineering
Structural Engineering
More...
Health Sciences
Basic Nursing Skills
Health Science Language Fundamentals
Veterinary Technology Medical Language
Cardiology
Clinical Surgery
More...
English
Grammar Fundamentals
Literary And Rhetorical Vocab
Elements Of Style Vocab
Introduction To English Major
Complete Advanced Sentences
Literature
Homonyms
More...
Math
Algebra Formulas
Basic Arithmetic: Measurements
Metric Conversions
Geometric Properties
Important Math Facts
Number Sense Vocab
Business Math
More...
Other Major Subjects
Science
Economics
History
Law
Performing-arts
Cooking
Logic & Reasoning
Trivia
Browse all subjects
Browse all tests
Most popular tests