SUBJECTS
|
BROWSE
|
CAREER CENTER
|
POPULAR
|
JOIN
|
LOGIN
Business Skills
|
Soft Skills
|
Basic Literacy
|
Certifications
About
|
Help
|
Privacy
|
Terms
|
Email
Search
Test your basic knowledge |
Hemeonc
Start Test
Study First
Subject
:
health-sciences
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What is hemophilia B?
Def in factor IX
40 to 50
Up - down - nl
Heinz bodies - seen in alpha thal and G6PD
2. iron deficiency anemia - esophageal web - atrophic glossitis
Lymphoma
Plummer - vinson syndrome
Polycythemia vera
Bernard soulier
3. What is the therapy for the M3 variant?
Lead poisoning - rRNA causes aggregration of ribosomes and basophilic stippling
B cells
Round densly staining nucleus with a small amount of pale cytoplasm
All trans retinoic acid
4. Back pain - hemoglobinuria
40 to 75
Glanzmann's throbmasthenia - GpIIb/IIIa - nl platelets - inc BT
Common a few days after oxidative stress in a pt with G6PD
Megaloblastic anemia (also hypersegmented PMNs - marrow failure)
5. Fibrotic obliteration of bone marow with teardrop cells
Warning
: Invalid argument supplied for foreach() in
/var/www/html/basicversity.com/show_quiz.php
on line
183
6. What are the four levels of alpha thal?
Defect in 4 - not compatible with life - defect in 3 - HbH disease - defect in 1/2 not associated with sig anemia
Hereditary spherocytosis - G6PD - sickle cell
...
Epoxide reductase - warfarin inhibits
7. What do you see a starry sky appearance in Burkitt
Sheets of lymphocytes interspersed with macs
Inc large vWF multimers - inc platelet aggregation and thrombosis
DIC - TTP- HUS - SLE malignant HTN - prostethic heart valves - aortic stenosis
B symptoms - fever night sweats - weight loss
8. What virus can cause an aplastic crisis in pts with HS?
Intrinsic - all factors except - VII - XIII
Induces differentiation of myeloblasts
Parvovirus
Malaria - Babesia
9. Where to T cells arise and mature - and migrate to...
Myelofibrosis (marow is crying being its fibrosed'
Down - up - down
MAHA
Bone marrow - thymus - blood (80% of circulating lymphos are T)
10. Target cell
Warning
: Invalid argument supplied for foreach() in
/var/www/html/basicversity.com/show_quiz.php
on line
183
11. What do eosinophils defend against and What do they use to do it?
Inducers of primary antibody response
Cromolyn sodium
Helminth infections major basic protein
IFN gama
12. What are the extrinsic hemolytic normocytic anemias?
Ankryin - band 4.1 or spectrin
...
Mantle cell lymphoma
40 to 50
13. What is the effected enzyme in acute intermittment porphyria?
Porphobilinogen deaminase aka uroporphyrinogen I synthase
Beta chain underproduced - asymptomatic - heterozygote
Dec
Tissue factor converst the VII and VIIa
14. In hemophilia A or B What do you see in the coag tests
AB - no antibodies
Nl PT - elevated PTT - intrinsic pathway defect
Beta 4
120 days
15. hemolytic in a newborn - dec ATP and rigid RBCs
Pyruvate kinase def - extravascular
Bone marrow infiltration - myelofibrosis
CNS and testis
Complications of sickle cell anemia
16. bcl -2 t(14;18) adults
Dec
B12 in fatty acid pathways leads to subacute combined degeneration
Mycosis fundgoides/Sezary syndrome
Follicular lymphoma - indolent course
17. Causes of iron def?
Bleeding - malnutrition/absorption - inc demand pregs
Hereditary elloptocytosis
Liver disease - abetalipoproteinemia - acntho = spiny
Antigen - antibody
18. Deficiency in GpIb
DIC
IgG - Warm is GREAT
Bernard soulier
Blasts > 5%
19. Acanthocyte (spur cell)
Liver disease - abetalipoproteinemia - acntho = spiny
Inc serum iron - normal TIBC - inc ferratin
< 1% - heparin - histamine - LTD-4 - other vasoactive amines
Follicular lymphoma - indolent course
20. How is beta thal minor dx
Sideroblastic anemia
Yes - via MHC II
Extrinsic - I - II - V - VII and X
Inc HbA2 on electrophoresis
21. What percentage of WBCs are monocytes?
2 to 10
Von Willebrand's disease
B12/folate def
TRAP (tartrate resistant acid phosphatase
22. What is the pathogenesis of TTP?
Inc lymphoctes - and less RS cells
Adult T cell lymphoma - presents with cutaneous lesions
Inc large vWF multimers - inc platelet aggregation and thrombosis
ATIII def
23. How does the therapy for M3 vairant work?
Chloride bicarb antiport system - - allows transport of C02 from periph to lungs
Induces differentiation of myeloblasts
Schistocytes - inc fibrin split products (D- dimers) - dec fibrinogen - dec factors V and VIII
Lymphoma
24. Serum iron - transferrin - ferritin lab values for hemochromatosis
Lead poisoning - rRNA causes aggregration of ribosomes and basophilic stippling
Up - down - up
Liver disease - abetalipoproteinemia - acntho = spiny
B cells
25. What is the characteristic lab finding on electrophoresis
Paraprotein spike - monoclonal protein
Intrinsic - all factors except - VII - XIII
Howell Jolly bodies
Spleen
26. What distinguishes multiple myeloma fromk Waldenstroms macroglobulinemia?
Prothrombin gene mutation
No lytic bone lesions in WM
120 days
Blod - tissue - MACS
27. what proteins can be defective in HS?
Ankryin - band 4.1 or spectrin
B antigena and A antibodes
Dec platelet survival and inc megakaryocytes - thrombocytopenia and inc BT
Schistocytes and inc LDH
28. What causes the jaundice in extravascular hemolysis
Myelofibrosis (marow is crying being its fibrosed'
Helminth infections major basic protein
Inc UCB
Sickle cell anemia
29. What percentage of WBCs are basophils - and What is found in their basophilic granules?
< 1% - heparin - histamine - LTD-4 - other vasoactive amines
Glycine and succinyl - coa
TAIL - thalassemias - anemia of chronic disease - iron def - lead poisoning
Inc UCB
30. inhibition of ferrochelatase and ALA dehydrogenase leading to dec heme synthesis - also inhibition of rRNA degradation
Dec
Inc large vWF multimers - inc platelet aggregation and thrombosis
Contiguous
Lead poisoning - rRNA causes aggregration of ribosomes and basophilic stippling
31. What do labs show in DIC?
Follicular lymphoma - indolent course
Schistocytes - inc fibrin split products (D- dimers) - dec fibrinogen - dec factors V and VIII
ADP and Ca
XIIa activates kallikrein - which activates plasmin (and converts HMWK to bradykinin
32. What does STOP Making New Thrombi stand for
Causes of DIC: Sepsis (gram neg) - Trauma - Obstetric complications - acute Pancreatitis - Malignancy - Nephrotic syndrome - Tranfusion
MGUS - monoclonal gammopathy of undetermined significance
Imatinib - anti bcr abl
CML
33. What activates the intrinsic pathway?
ATIII def
Collagen - BM - activated platelets
Petechiae
Beta chain underproduced - asymptomatic - heterozygote
34. Oxidation of iron - denatured hemoglobin preceipitation damage to RBC membrane - formation of bite cells
2 to 10
Mycosis fundgoides/Sezary syndrome
TRAP (tartrate resistant acid phosphatase
Heinz bodies - seen in alpha thal and G6PD
35. What is relative polycythemia
CML
Sideroblastic anemia
XIIa activates kallikrein - which activates plasmin (and converts HMWK to bradykinin
Dec plasma volume
36. t(11;14)
Mantle cell lymphoma
B12/folate def
Inc bleeding time - microhemorrhage: mucuous membrane bleeding - epitaxis - petechiae - purpura - possible thrombocytopenia
Idiopathic thrombocytopenia (ITP)
37. Inherited deficiency of antithrombin; reduced inc in PTT after administration of heparin
ATIII def
Glanzmann's throbmasthenia - GpIIb/IIIa - nl platelets - inc BT
IFN gama
Painful abdomen (also in lead poisoning) - red wine colored urine - polyneuropathy - psychological distrubances - precipated by drugs -
38. What cell is primarily involved in non Hod lymph
Factor V resistant to activated protein C's inhibition
Direct coombs - agglutinate if RBCs are coated with Ig
DNA synth impaired - maturation of nucleus delayed relative to maturation of cytoplasm
B cells
39. anisocytosis
TXA2 - dec blood flow - inc platelet aggregation
Varying sizes
40 to 75
120 days
40. When is the peak incidence for nonHod lymphoma
Common a few days after oxidative stress in a pt with G6PD
20 to 40
Folate def
Hb Barts - gamma4 in defect in all 4 alpha genes
41. What is the life span of a normal RBC
Fe def - thal - pb poison - sideroblastic anemia
Indirect coombs - agglutinate if serum anti RBC surface Ig
120 days
Gp1b - bernard - soulier - dec platelets (giant platelets not counted) - inc BT
42. What do labs show in ITP?
Dec platelet survival and inc megakaryocytes - thrombocytopenia and inc BT
Bite cells and Heinz bodies
Mantle cell lymphoma
Africa = Jaw lesion - US = pelvis or abdomen
43. What role does antithrombin play?
EBV
Defect in 4 - not compatible with life - defect in 3 - HbH disease - defect in 1/2 not associated with sig anemia
Incactivates II - VII - IX - X - XI - XII
Eleveated PT - PTT
44. What is the mutation in HbS
Sheets of lymphocytes interspersed with macs
Valine for glutamate
Sickle cell anemia
XIIa activates kallikrein - which activates plasmin (and converts HMWK to bradykinin
45. Bone pain plus anemia
Multiple myeloma
CD15 and CD30 pos
Positive osmootic fragility test and splenectomy
They bind vWF via GpIb
46. What is the coombs test results in AIHA?
Pos
HIV or immunosupression
Anemia of chronic disease - Aplastic anemia - kidney disease
Decrease EPO
47. Can B cells function as APCs?
Common a few days after oxidative stress in a pt with G6PD
Orotic aciduria
Ferrocheletase and ALA dehydrogenase
Yes - via MHC II
48. What do the dense granules contain in platelets
VIII
Cold - seen in CLL - mycoplasma pneumoniae infections or infectious mononucleosis
ADP and Ca
Signs and sx of aplastic anemia
49. What percentage of WBCs are eosinophils?
1 to 6
Tissue factor converst the VII and VIIa
Examples of oxidative stress
2 to 10
50. Is G6PD intravascular or extravascular
Spleen
B6
Intravascular
Marrow - marrow - follicles of lymph nodes - white pulp of spleen (unencapsulated lymphoid tissue)
Sorry!:) No result found.
Can you answer 50 questions in 15 minutes?
Let me suggest you:
Browse all subjects
Browse all tests
Most popular tests
Major Subjects
Tests & Exams
AP
CLEP
DSST
GRE
SAT
GMAT
Certifications
CISSP go to https://www.isc2.org/
PMP
ITIL
RHCE
MCTS
More...
IT Skills
Android Programming
Data Modeling
Objective C Programming
Basic Python Programming
Adobe Illustrator
More...
Business Skills
Advertising Techniques
Business Accounting Basics
Business Strategy
Human Resource Management
Marketing Basics
More...
Soft Skills
Body Language
People Skills
Public Speaking
Persuasion
Job Hunting And Resumes
More...
Vocabulary
GRE Vocab
SAT Vocab
TOEFL Essential Vocab
Basic English Words For All
Global Words You Should Know
Business English
More...
Languages
AP German Vocab
AP Latin Vocab
SAT Subject Test: French
Italian Survival
Norwegian Survival
More...
Engineering
Audio Engineering
Computer Science Engineering
Aerospace Engineering
Chemical Engineering
Structural Engineering
More...
Health Sciences
Basic Nursing Skills
Health Science Language Fundamentals
Veterinary Technology Medical Language
Cardiology
Clinical Surgery
More...
English
Grammar Fundamentals
Literary And Rhetorical Vocab
Elements Of Style Vocab
Introduction To English Major
Complete Advanced Sentences
Literature
Homonyms
More...
Math
Algebra Formulas
Basic Arithmetic: Measurements
Metric Conversions
Geometric Properties
Important Math Facts
Number Sense Vocab
Business Math
More...
Other Major Subjects
Science
Economics
History
Law
Performing-arts
Cooking
Logic & Reasoning
Trivia
Browse all subjects
Browse all tests
Most popular tests