SUBJECTS
|
BROWSE
|
CAREER CENTER
|
POPULAR
|
JOIN
|
LOGIN
Business Skills
|
Soft Skills
|
Basic Literacy
|
Certifications
About
|
Help
|
Privacy
|
Terms
|
Email
Search
Test your basic knowledge |
Hemeonc
Start Test
Study First
Subject
:
health-sciences
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What is the enzyme defect in Porphyria cutanea tarda
Uroporphyrinogen decarboxylase
Sickle cell anemia
Blood
Collagen - BM - activated platelets
2. What indicated a good prognosis in Hodgkin lymphoma?
Inc lymphoctes - and less RS cells
Positive osmootic fragility test and splenectomy
Intravascular hemolysis
Lysine for glutamate at position 6
3. What do labs show in DIC?
Gp1b
Schistocytes - inc fibrin split products (D- dimers) - dec fibrinogen - dec factors V and VIII
Blasts > 5%
Imatinib - anti bcr abl
4. What are the main associations with multiple myeloma?
Inc
Inc suscept to infxn - primary amyloidosis - punched out lytic bone lesions - M spike - Ig light chains in urine - Rouleaud formations (stacked RBCs)
Multiple myeloma
Anemia of chronic disease - Aplastic anemia - kidney disease
5. Defect in proteins interacting with RBC membrane skeleton and plasma membrane
Hb Barts - gamma4 in defect in all 4 alpha genes
B6
Hereditary spherocytosis
T(12;21)
6. Blood type A
Folate/B12 - nonmegaoblastic anemias - liver dz - EtOH (non folate/B12) reticulocytosis - metabolic disorder - drugs
A antigen and B antibodies
Varying shapes
Low in CML
7. What is the most common nonhodgkin lymphoma
B symptoms - fever night sweats - weight loss
No lytic bone lesions in WM
Diffuse Large b cell lymphoma
Deficiency in factor VIII
8. What is the effect of ACE on bradykinin
Inactivates it
CML
Factor V resistant to activated protein C's inhibition
Inc serum iron - normal TIBC - inc ferratin
9. Oxidation of iron - denatured hemoglobin preceipitation damage to RBC membrane - formation of bite cells
Polycythemia vera with inc plasma volume - inc RBCs - inc EPO
Heinz bodies - seen in alpha thal and G6PD
Inhibits thrombin - ixa - xa - xiia - and activated by heparin
DIC - TTP/HUS - traumatic hemolysis
10. Which cell is neoplastic in multiple myeloma
No lytic bone lesions in WM
Erythroblastosis fetalis - Rh or other blood antigen incompatibility
Ticlopidine/clopidogrel
Plasma cell
11. What does Vit K deficiency cause?
Dec synthesis of factors 1972 - protein C/S
G6PD
MHC II and Fc receptors
Splicing sites and promotor sequences
12. What does STOP Making New Thrombi stand for
TRAP (tartrate resistant acid phosphatase
Abciximab
Indirect coombs - agglutinate if serum anti RBC surface Ig
Causes of DIC: Sepsis (gram neg) - Trauma - Obstetric complications - acute Pancreatitis - Malignancy - Nephrotic syndrome - Tranfusion
13. What is the presenting scenario for TTP?
PENTAD: neurologic sx - renal sx - fever - thrombocytopenia - MAHA
Polycythemia vera with inc plasma volume - inc RBCs - inc EPO
Blasts > 5%
Malaria - Babesia
14. Ringed sideroblasts
Beta thal
Cromolyn sodium
VWF carries/protects factor VIII
Sideroblastic anemia
15. What does increasing heme do to ALA synthase activity
Blistering cutaneous photosens - most common porphyria
< 1% - heparin - histamine - LTD-4 - other vasoactive amines
Bone marrow - thymus - blood (80% of circulating lymphos are T)
Dec
16. What causes hydrops fetalis
Myelofibrosis (marow is crying being its fibrosed'
AML
Hb Barts - gamma4 in defect in all 4 alpha genes
MAHA
17. Serum iron - transferrin - ferritin lab values for pregs - OCP use
Malnutrition - malabsoprtion - impaired metabolism - inc requirement as in an hemolytic anemia or pregnancy
120 days
Nl - up - nl
VWD
18. Macro - ovalocyte
Inc HbA2 on electrophoresis
HbC disease - Asplenia - Liver disease - thalassemia - 'HALT the hunter said to his target'
Megaloblastic anemia (also hypersegmented PMNs - marrow failure)
Antigen - antibody
19. What do you see in vit K def
TAIL - thalassemias - anemia of chronic disease - iron def - lead poisoning
Eleveated PT - PTT
5- FU - AZT - hydroxyurea
SLE - CLL - alpha methyldopa
20. What does 'Neutrophils Like Making Everything Better' stand for?
Tissue
Malaria - Babesia
WBC diff highest to lowest: neutrophils - lymphocytes - monocytes - eosinophils - basophils
DNA synth impaired - maturation of nucleus delayed relative to maturation of cytoplasm
21. What finding you do you see in patients after splenectomy
Howell - Jolly bodies - hypo/asplenia
40 to 75
Howell Jolly bodies
Leukemia
22. What is HbH
Induces differentiation of myeloblasts
No platelet clumping
1 to 6
Beta 4
23. What chromosomal translocation is associated with a better prognosis in All
VWF carries/protects factor VIII
Liver disease - abetalipoproteinemia - acntho = spiny
Dec platelet survival and inc megakaryocytes - thrombocytopenia and inc BT
T(12;21)
24. CD5+ - poor prognosis - t(11;14)
DIC
Tissue factor converst the VII and VIIa
Mantle cell - older males
Inc UCB
25. Inherited deficiency of antithrombin; reduced inc in PTT after administration of heparin
Megaloblastic anemia (also hypersegmented PMNs - marrow failure)
Inflammation leads to inc hepcidin causing a dec in release from iron from macs: dec serum fe - dec TIBC - inc ferritin
Mycosis fundgoides/Sezary syndrome
ATIII def
26. Serum iron - transferrin - ferritin lab values for anemia of chronic disease
Dec
Peroxidase
Bite cells and Heinz bodies
Down - down - up
27. What do labs show in ITP?
No
MGUS - monoclonal gammopathy of undetermined significance
Dec platelet survival and inc megakaryocytes - thrombocytopenia and inc BT
Folate def
28. What do the iron studies show in sideroblastic anemia
Inappropriate absolute with inc RBCs and EPO
Inc serum iron - normal TIBC - inc ferratin
VIII
Liver disease - abetalipoproteinemia - acntho = spiny
29. Schisotcyte - helmet cell
Hereditary spherocytosis
DIC - TTP/HUS - traumatic hemolysis
Factor V resistant to activated protein C's inhibition
Abciximab
30. Elliptocyte
Inc UCB
Hereditary elloptocytosis
Extrinsic - I - II - V - VII and X
Bleeding - malnutrition/absorption - inc demand pregs
31. What are the azuraphilic granules in PMNs
Myelofibrosis (marow is crying being its fibrosed'
Lysosomes
Defect in 4 - not compatible with life - defect in 3 - HbH disease - defect in 1/2 not associated with sig anemia
HbC disease - Asplenia - Liver disease - thalassemia - 'HALT the hunter said to his target'
32. X linked defect in delta aminolevulinic acid synthase gene causes a defect in hemesynthesis
Sideroblastic anemia
M3 AML (acute promyelocytic leukemia)
Factor V Leiden
Leukemoid reaction
33. Target cell
Warning
: Invalid argument supplied for foreach() in
/var/www/html/basicversity.com/show_quiz.php
on line
183
34. What is the aggregation phase of ppf?
Fibrinogen bind GpIIb/IIIa and links platelts
HIV or immunosupression
Myelofibrosis (marow is crying being its fibrosed'
Howell - Jolly bodies - hypo/asplenia
35. What is the difference of presentation of Burkitt in Africa vs the United States
Megakaryocytes
Africa = Jaw lesion - US = pelvis or abdomen
Dimercaprol and EDTA 1st line of treatment - succimer for kids - it sucks to be a kid who eats lead
Histaminase and arylsulfatase
36. iron deficiency anemia - esophageal web - atrophic glossitis
VWF carries/protects factor VIII
Myelofibrosis (marow is crying being its fibrosed'
Howell - Jolly bodies - hypo/asplenia
Plummer - vinson syndrome
37. What signal activates MACS
Schistocytes - inc fibrin split products (D- dimers) - dec fibrinogen - dec factors V and VIII
No platelet clumping
IFN gama
Multiple myeloma
38. Ddx for microcytic anemia
Fe def - thal - pb poison - sideroblastic anemia
Cold - seen in CLL - mycoplasma pneumoniae infections or infectious mononucleosis
Reed - sternberg cells
Adult T cell lymphoma - presents with cutaneous lesions
39. What cell is primarily involved in non Hod lymph
B cells
Leukemoid reaction
B12 def
Insufficient intake as with strict vegans - malabsorption as in crohns - pernicious anemia - diphyllobothrium
40. What does the large SA:volume ratio in RBCs help facilitate?
Gp1b - bernard - soulier - dec platelets (giant platelets not counted) - inc BT
Langerhans cells
Easy gas exchange
VWD
41. t(8;14) c - myc gene
No lytic bone lesions in WM
Beta thal
Burkitt lymphoma
Insufficient intake as with strict vegans - malabsorption as in crohns - pernicious anemia - diphyllobothrium
42. Bite cell
Hodgkin
Inc HbA2 on electrophoresis
Inactivates it
G6PD
43. What are the two substances produced by eosinophils help limit the reaction following mast cell degranulation?
Histaminase and arylsulfatase
TXA2 - dec blood flow - inc platelet aggregation
Macrohemorrhage - hemarthroses - easy bruising
Marrow - marrow - follicles of lymph nodes - white pulp of spleen (unencapsulated lymphoid tissue)
44. What are the presenting symptoms of porphyria cutanea tarda
Multiple - peripheral nodes - extranodal involvement - noncontiguous spread
Anti Rh
Ankryin - band 4.1 or spectrin
Blistering cutaneous photosens - most common porphyria
45. Deficiency in vWF
Warning
: Invalid argument supplied for foreach() in
/var/www/html/basicversity.com/show_quiz.php
on line
183
46. what proteins can be defective in HS?
Ankryin - band 4.1 or spectrin
...
Low O2 in papilla; can also get microhematuria from medullary infarcts
XIIa activates kallikrein - which activates plasmin (and converts HMWK to bradykinin
47. What is the pattern of involvement and spread for nonHod lympho
Factor V resistant to activated protein C's inhibition
Cromolyn sodium
Multiple - peripheral nodes - extranodal involvement - noncontiguous spread
VWD
48. X linked - dec glutathione inc RBC susceptibility to oxidative stress
Inappropriate absolute with inc RBCs and EPO
CD15 and CD30 pos
G6PD
Inflammation leads to inc hepcidin causing a dec in release from iron from macs: dec serum fe - dec TIBC - inc ferritin
49. Eosinophils are highly phagocytic For what kind of complex?
Ticlopidine/clopidogrel
Antigen - antibody
Birbeck granules
Dimercaprol and EDTA 1st line of treatment - succimer for kids - it sucks to be a kid who eats lead
50. What does CRAB stand for in multiple myeloma
Down - up - down
HyperCalcemia - Renal insuff - Anemia - Bone lytic lesions/Back pain
Malnutrition - malabsoprtion - impaired metabolism - inc requirement as in an hemolytic anemia or pregnancy
Acts to stabilize platelet plug
Sorry!:) No result found.
Can you answer 50 questions in 15 minutes?
Let me suggest you:
Browse all subjects
Browse all tests
Most popular tests
Major Subjects
Tests & Exams
AP
CLEP
DSST
GRE
SAT
GMAT
Certifications
CISSP go to https://www.isc2.org/
PMP
ITIL
RHCE
MCTS
More...
IT Skills
Android Programming
Data Modeling
Objective C Programming
Basic Python Programming
Adobe Illustrator
More...
Business Skills
Advertising Techniques
Business Accounting Basics
Business Strategy
Human Resource Management
Marketing Basics
More...
Soft Skills
Body Language
People Skills
Public Speaking
Persuasion
Job Hunting And Resumes
More...
Vocabulary
GRE Vocab
SAT Vocab
TOEFL Essential Vocab
Basic English Words For All
Global Words You Should Know
Business English
More...
Languages
AP German Vocab
AP Latin Vocab
SAT Subject Test: French
Italian Survival
Norwegian Survival
More...
Engineering
Audio Engineering
Computer Science Engineering
Aerospace Engineering
Chemical Engineering
Structural Engineering
More...
Health Sciences
Basic Nursing Skills
Health Science Language Fundamentals
Veterinary Technology Medical Language
Cardiology
Clinical Surgery
More...
English
Grammar Fundamentals
Literary And Rhetorical Vocab
Elements Of Style Vocab
Introduction To English Major
Complete Advanced Sentences
Literature
Homonyms
More...
Math
Algebra Formulas
Basic Arithmetic: Measurements
Metric Conversions
Geometric Properties
Important Math Facts
Number Sense Vocab
Business Math
More...
Other Major Subjects
Science
Economics
History
Law
Performing-arts
Cooking
Logic & Reasoning
Trivia
Browse all subjects
Browse all tests
Most popular tests