Test your basic knowledge |

Immunology

Instructions:

Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can study here.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. How do NK cells kill?
Innate
Severe pyogenic sinus and respiratory infections - inc suscept to type III hypersen rxn
Ceilac disase
Perforins and granzymes to induce apoptosis of virally infected or tumor cells

2. What is the arthus rxn?
Type III hypersens rxn after intradermal rxn with antigen - antibodies in the skin causing edema - necrosis and activation of complement
Pemphigus vulgaris
Everything else - not right arm and right half of head
2

3. Which cell mediates the type IV hypersens rxn?
IV
CD8 cells
Graves' dz
PAIR - psoriasis - ankylosing spondylitis - inflammatory bowel dz - reiter's syndrome

4. Which antibody mediates type II and type III hypersens rxn
IgG
Il -4
IL-12
Adaptive

5. What kind of bacteria do macrophages remove from the spleen?
Encapsulated - S SHiN (salmonella - S.pneumo - H. influ - N. menin
RA - DM type 1
Scleroderma CREST
APCs - and DR - DP and DQ

6. anti U1 RNP
DM type 1
Paracortex
MHC II - B7 - CD40 - CD14 - receptors for Fc and C3b
Mixed connective tissue disease

7. What are the two signals in helper T activation?
Salmonella - 2 flaggellar variants - Borrelia - relapsing fever - N. gono - pilus protein
Interfereon alpha - beta gamma. Alpha/beta inhibit viral protein synthesis - gamma upregulate MHC I and II - all three activate NK cells
III
Signal 1 = APC - signal 2 = B7 and CD28

8. What is the role of CD4 cels
CD3 - CD28 - helper t - CD4 - CD40L - cyto t CD8
Opsonization - neutralization and complement activation
Help B cells make antibody - secrete IFN gamma to activate macs
IgG - IgM GM makes classic cars

9. anti - Jo 1
Poly/dermato myositis
T- lymphos - Transplant - TB skin test - Touching (contact dermatitis)
IL-10
IgG - IgM GM makes classic cars

10. Which type of hypersens rxn is delayed
IV
Tetanus - Botulinum toxin - HBV or Rabies (To Be Healed Rapidly
IgE
Fab

11. Which is the most abundant immunoglobulin in the blood?
IgG
Mixed connective tissue disease
Mature t cells - epithelial reticular cells - Hassalls corpuscles
Salmonella - 2 flaggellar variants - Borrelia - relapsing fever - N. gono - pilus protein

12. Which immunoglobulin is found in breast milk - tears - saliva - and mucous
Interfereon alpha - beta gamma. Alpha/beta inhibit viral protein synthesis - gamma upregulate MHC I and II - all three activate NK cells
Type III hypersens rxn after intradermal rxn with antigen - antibodies in the skin causing edema - necrosis and activation of complement
IgG
IgA

13. Antimitochondrial
Primary biliary cirrohosis
Chediak Higashi
Ataxia telangectasia
Perforins and granzymes to induce apoptosis of virally infected or tumor cells

14. Which antibody (IgM or IgG) crosses the placenta?
Superficial inguinal pectinate line
IgG
Corticomedullary junction
RA - DM type 1

15. Which type of hypersens rxn is immune complex mediate
Sjorgen's syndrome
III
Howell - Jolly bodies - Target cells - thrombocytosis
Major shift minor drift

16. Which bacteria secrete superantigen
Hashimotos
S. aureus and S. pyogenes
Primary biliary cirrohosis
Everything else - not right arm and right half of head

17. Can lipopolysaccharide from cell envelope of of gram neg bacteria induce immunologic memory?
Other vasculitidies
IgM and IgD
No - peptides only can can be presented on MHC molecules
Goodpastures

18. HLA- B27

Warning: Invalid argument supplied for foreach() in /var/www/html/basicversity.com/show_quiz.php on line 183

19. What are the 4 T's of type IV hypersense
T- lymphos - Transplant - TB skin test - Touching (contact dermatitis)
Innate
Wilskott Aldrich (TIE = thrombocytopenia - infections - eczema) high IgE and IgA - low IgM
Fc and Fab

20. What cytokines to Th2 cells secrete?
IgE
Ceilac disase
Complement mediated lysis of RBCs and paroxysmal nocturnal hemoglobinuria
IL-4 - 5 - 10

21. c - ANCA
SLE
Wegeners granulomatosis
Uncoordinated release of IFN gamm leading to IL-1 - IL 6 and TNF alpha from MACS - via crosslinking of TCR and MHC II
Right arm and right half of head

22. Anticentromere
Scleroderma CREST
APCs - and DR - DP and DQ
Il -4
Signal 1 = IL-4 -5 -6 signal 2 = CD40 receptor on b cell binds CD40L on Th cell

23. Which cytokine induces Th1 cell profile in CD4 cells
No - peptides only can can be presented on MHC molecules
Mature t cells - epithelial reticular cells - Hassalls corpuscles
IL-12
CD8 cells

24. HLA- DR5
Complement mediated lysis of RBCs and paroxysmal nocturnal hemoglobinuria
Encapsulated - S SHiN (salmonella - S.pneumo - H. influ - N. menin
Goodpastures
Pernicious anemia (to B12 def) - hashimotos thyroiditis

25. Which type of hypersens rxn is the arthus rxn
Salmonella - 2 flaggellar variants - Borrelia - relapsing fever - N. gono - pilus protein
Everything else - not right arm and right half of head
III
Type III hypersens rxn after intradermal rxn with antigen - antibodies in the skin causing edema - necrosis and activation of complement

26. Which areas of the body are drained by the axillary lymph node
Upper limb and breast
Signal 1 = IL-4 -5 -6 signal 2 = CD40 receptor on b cell binds CD40L on Th cell
All nucleated cells (no RBCs) A - B - C
MHC II - B7 - CD40 - CD14 - receptors for Fc and C3b

27. Defect in B cell maturation
Hashimotos
CD21
Acute: vasculitis of graft vessels and interstitial lymphcytic infiltrate
Common variable immunodeficiency (CVID)

28. Which cytokine inhibits Th1 cells
IgG
IL-10
Complement mediated lysis of RBCs and paroxysmal nocturnal hemoglobinuria
IgG

29. What happens in the follicle of the lymph node
B cell localization and proliferation
Right arm and right half of head
Fc and Fab
Mesenchyme

30. Which MHC complex to CD4 cells bind
Innate
MHC II 4 x 2=8
Uncoordinated release of IFN gamm leading to IL-1 - IL 6 and TNF alpha from MACS - via crosslinking of TCR and MHC II
Major shift minor drift

31. Which complement proteins make up the MAC
C5b -9
IgG
Encapsulated - S SHiN (salmonella - S.pneumo - H. influ - N. menin
Ig - CD19 - 20 - 21 - CD40 - MHCII - B7

32. How do CD8 cells kill?
Mesenchyme
Perforin - granzyme - granulysin
Primary biliary cirrohosis
Hereditary angioedema

33. What are the three APCs
Perforins and granzymes to induce apoptosis of virally infected or tumor cells
CD56
Macs - dendritic cell - B cell
DM type 1

34. Transplant rejection: preformed host antibody mediated
Hyperacute : occlusion - ischemia - necrosis
Chronic granulomatous disease
IL-1 = fever - IL-2 = T cells - IL-3 = bone marrow - IL-4 = IgE - IL-5 = IgA
IgG

35. What does HOT- T- Bone stEAk stand for?
Signal 1 = IL-4 -5 -6 signal 2 = CD40 receptor on b cell binds CD40L on Th cell
Chronic granulomatous disease
IL-1 = fever - IL-2 = T cells - IL-3 = bone marrow - IL-4 = IgE - IL-5 = IgA
Hereditary angioedema

36. What does a deficiency in C1 esterase inhibitor lead to?
Ceilac disase
APCs - and DR - DP and DQ
Hereditary angioedema
Wilskott Aldrich (TIE = thrombocytopenia - infections - eczema) high IgE and IgA - low IgM

37. What is the difference in antigenic variation in viruses
Autoimmune hepatitis
Opsonization - neutralization and complement activation
S. aureus and S. pyogenes
Major shift minor drift

38. How are NK cells stimulated?
IgE
Upper limb and breast
IL-12 - IFN- beta. IFN- alpha
Uncoordinated release of IFN gamm leading to IL-1 - IL 6 and TNF alpha from MACS - via crosslinking of TCR and MHC II

39. Which immunoglobulin is a pentamer
IgM
IgG
CD3 - CD28 - helper t - CD4 - CD40L - cyto t CD8
Hyper IgE syndrome (Job's)

40. antimicrosomal - antithyroglobulin
Wegeners granulomatosis
Hashimotos
S. aureus and S. pyogenes
II

41. X- linked recessive defect with progessive deletion of B and T cells
Pemphigus vulgaris
Right arm and right half of head
Wilskott Aldrich (TIE = thrombocytopenia - infections - eczema) high IgE and IgA - low IgM
Mesenchyme

42. Which lymph node drains the anal canal below
Superficial inguinal pectinate line
Signal 1 =peptide expressed on MHC I - signal 2 = Il -2
Encapsulated - S SHiN (salmonella - S.pneumo - H. influ - N. menin
Tetanus - Botulinum toxin - HBV or Rabies (To Be Healed Rapidly

43. Which antibodies activate the classic pathway
IgG - IgM GM makes classic cars
Trypanosomes - programmed rearrangement
Type III hypersens rxn after intradermal rxn with antigen - antibodies in the skin causing edema - necrosis and activation of complement
Goodpastures

44. What do you find in the medulla of the thymus?
III
Graves' dz
Complement mediated lysis of RBCs and paroxysmal nocturnal hemoglobinuria
Mature t cells - epithelial reticular cells - Hassalls corpuscles

45. What is the clinical picture for serum sickness?
Caused by drugs mostly - fever - urticaria - arthralgias - proteinuria - lymphadenopathy 5-10 days after exposure
Trypanosomes - programmed rearrangement
III
S. aureus and S. pyogenes

46. Anti Scl 70 (DNA topo I
Neisseria bacteremia
Chronic: fibrosis of graft tissue and blood vessels
Scleroderma diffuse
PAIR - psoriasis - ankylosing spondylitis - inflammatory bowel dz - reiter's syndrome

47. transplant rejection: T cell and antibody mediated vasular damage
RA
C5b -9
Chronic: fibrosis of graft tissue and blood vessels
Trypanosomes - programmed rearrangement

48. Cell surface receptors on B cels
Mesenchyme
PMNs recruited by IL-8 to clear infxns
Hyper IgM
Ig - CD19 - 20 - 21 - CD40 - MHCII - B7

49. Anti ds DNA - anti Smith
Selective Ig def - IgA most common
CD56
SLE
Graves' dz

50. HLA- DR4
Hereditary angioedema
Hyperacute : occlusion - ischemia - necrosis
RA - DM type 1
Graft versus host: severe organ dysfunction - maculopapular rash - jaundice - hepatosplenomegaly - diarrhea often in bone marrown and liver transplant

Can you answer 50 questions in 15 minutes?

Major Subjects
Tests & Exams AP CLEP DSST GRE SAT GMAT	Certifications CISSP go to https://www.isc2.org/ PMP ITIL RHCE MCTS More...	IT Skills Android Programming Data Modeling Objective C Programming Basic Python Programming Adobe Illustrator More...	Business Skills Advertising Techniques Business Accounting Basics Business Strategy Human Resource Management Marketing Basics More...
Soft Skills Body Language People Skills Public Speaking Persuasion Job Hunting And Resumes More...	Vocabulary GRE Vocab SAT Vocab TOEFL Essential Vocab Basic English Words For All Global Words You Should Know Business English More...	Languages AP German Vocab AP Latin Vocab SAT Subject Test: French Italian Survival Norwegian Survival More...	Engineering Audio Engineering Computer Science Engineering Aerospace Engineering Chemical Engineering Structural Engineering More...
Health Sciences Basic Nursing Skills Health Science Language Fundamentals Veterinary Technology Medical Language Cardiology Clinical Surgery More...	English Grammar Fundamentals Literary And Rhetorical Vocab Elements Of Style Vocab Introduction To English Major Complete Advanced Sentences Literature Homonyms More...	Math Algebra Formulas Basic Arithmetic: Measurements Metric Conversions Geometric Properties Important Math Facts Number Sense Vocab Business Math More...	Other Major Subjects Science Economics History Law Performing-arts Cooking Logic & Reasoning Trivia

Test your basic knowledge |

Immunology

Can you answer 50 questions in 15 minutes?

Let me suggest you:

Browse all subjects

Browse all tests

Most popular tests

Major Subjects

Tests & Exams

Certifications

IT Skills

Business Skills

Soft Skills

Vocabulary

Languages

Engineering

Health Sciences

English

Math

Other Major Subjects

Browse all subjects

Browse all tests

Most popular tests