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KJZ PP Clues

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. 2 weeks post URI
Autoimmune Antibodies found in Scleroderma
Bacteria w/ toxins that inhibit EF-2
When does minimal change dz occur?
Tx for Hypercholesterolemia

2. Melanoma
Donovan body
Actions of E. coli
S-100
Causes of low volume state with acidosis (not alkalosis)

3. CMV
Erythema marginatum
1 dose tx for Gonorrhea
P450 Dependent
MC Infection in HIV

4. 2nd Messenger - Parasympathetic - anabolic
Autoimmune Antibodies found in Rheumatoid Arthritis
cGMP
Periods of rapid growth
Staph Epidermiditis

5. Rabies
Negri body
Varicella Zoster
Autoimmune Antibodies found in Pemphigus Vulgaris
Autoimmune Antibodies found in Primary Biliary Cirrhosis

6. Unique N- terminal sequence - Chronic active dz - Hodgkin's dz
Crescent shaped Protozoa
Nephrotic Syndrome
AA Amyloidosis
How do you tell catalas positive Staphylococci apart?

7. Pancreatitis (EtOH) - Kidney stones (bloody urine) - AAA (ripping - tearing pain) - Ischemic Bowel (bloody diarrhea)
CEA
4 causes of severe abdominal pain
Drugs that blast BM
Negri body

8. Xanthelasmas on eyelids & face - Increased risk for pancreatitis
TH0 secrete
Job of LDL
Councilman body
Elevated TGs

9. Glu - Gln
Autoimmune Antibodies found in Graves
T- Helper cells
CEA
Places where amino acids feed in/out of TCA cycle: a - ketoglutarate

10. Leigh's dz: subacute necrotizing encephalomyelopathy - progressive ?IQ - seizures - ataxia - cytochrome oxidase deficiency - Leber's dz: hereditary optic atrophy
Autoimmune Antibodies found in Primary Biliary Cirrhosis
Mitochondrial diseases
Heinz body
Jones Criteria (J<3NES)

11. Leishmaniasis
Donovan body
Ions responsible for different parts of the EKG
ret
Translocation 17:22

12. Pro
Places where amino acids feed in/out of TCA cycle: Fumerate
Drugs that cause cardic fibrosis
Amino acid subgroups: N- Bonds
Ca++

13. Herpes
Crohn's d
Cowdry Type A body
bcl -2
TB Treatments

14. To test: CaEDTA - In plasma: Penicillamine - In BM: Dimeraprol
MC Renal dz in Blacks/Hispanics
Places where amino acids feed in/out of TCA cycle: Succinyl CoA
Seborrheic dermatitis
Lead chelator

15. Disease does not effect parents - Disease may be seen in siblings & uncles - Often early onset (early dx) - Disease only present when both alleles are mutant - Horizontal transmission - Usu enzyme defects (Inborn errors of metabolism)
IP3/DAG
Autoimmune Antibodies found in Alopecia Areata
MC Nephrotic dz in kids
Characteristics of Autosomal Recessive Inheritance

16. Gly - Ala - Ser
MC Renal dz in Blacks/Hispanics
Odd MCC of Death
Places where amino acids feed in/out of TCA cycle: Pyruvate
Negative stranded RNA

17. 'SIADH' - Small cell ca - Increased Intracranial Pressure - A Pain - Drugs - Hypoxia
Cancer associated with urticaria (hives)
Erythema marginatum
5 causes of SIADH
Low Complement Bugs

18. Retinoblastoma
Names of macrophages in specific tissue types: 1. Brain 2. Lung 3. Liver 4. Spleen 5. Kidney 6. LN 7. Skin 8. Bone 9. CT
Rb
1 dose tx Vaginal Candidiasis
Citrobacter

19. In collecting duct - Absorbs ammonia in the liver - Cause of hepato - renal syndrome
Enzymes ONLY seen in glycolysis
MCC of newborn meningitis
Tx for Hypercholesterolemia
Glutaminase

20. Necator Americanus - Ascaris lumbricoides - Schistosomiasis - Strongyloides - Ankylostoma
Encapsulated yeast
Oddities about listeria
TH0 secrete
Pulmonary Infiltrate w/ Eosinophilia

21. Metronidazole
1 dose tx of Trichomonas
MCC Pneumonia 6 wks - 18 yrs
Drugs that blast BM
Crescent shaped Protozoa

22. Ca pyrophosphate - + birefringent crystals - rhomboid crystals - MC older pts - Seen equally in both genders - tx = colchicine
Oxalate stones in 3 yo white female
Pseudogout
Zebra body
Rb

23. Azithromycin 1 gm - Ceftriaxone 250 mg IM
bcl -2
Neural Crest Makes?
1 dose tx for H. ducreyi
Phage Mediated Toxins

24. Niemann - Pick dz
P450 Dependent
Zebra body
Drugs that blast BM
Type I Renal Tubular Acidosis

25. Crohn's diesase
Oxalate stones in adult male or female
CD4 counts to start treatment in HIV pt
Structures with no known function
P450 Inhibitors

26. Transposition of great arteries - Tetralogy of Fallot - Truncus Arteriosus - Tricuspid atresia - Total anomalous pulmonary venous return - Hypoplastic L Heart Syndrome - Ebstein's Anomaly - Aortic atresia - Pulmonary atresia
Cyanotic heart diseases
P450 Inducers
Phases of Atrial Action Potential
Oxalate stones in 5 yo black female

27. Legionella - Pneumocystis - H. pylori - Bartonella henselae - Candida
Cause dysguzia
CD4 counts to start treatment in HIV pt
Donovan body
Silver staining bugs

28. Intraductal Carcinoma

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29. MEN II - MEN III
ret
Cancer associated with Erythema nodosum
Roseola
Nephrotic Syndrome

30. Hypermagnesia - Hypercalcemia (except atrium) - Hypokalemia - Hypernatremia
Cancer associated with Actinic keratosis
T- cytotoxic cells
Aschoff body
Less likely to depolarize

31. Mycoplasma - Nocardia (partially - gram +) - Cryptosporidium (partially - protozoa)
4 sources of renal acid
Ca++
Encapsulated yeast
Acid fast organisms

32. Gene = on chr 7 - 2nd messenger is IP3/DAG - PIlocarpine can be used to treat (??)
Cystic fibrosis
Measles
MC Nephrotic dz in adults
AL Amyloidosis

33. Smoking - Alcohol - Nitrates - Japanes
Esophageal/gastric ca risk factors
Causes of Papillary Necrosis
MC Nephrotic dz in kids
Job of VLDL

34. Strep salivarius
l - myc
Hormones produced by small cell ca of lung
Used for Cold Agglutinin Testing
Macrolides

35. Only lipoprotein to carry cholesterol - Breakdown product of VLDL
Job of LDL
Negri body
Newborn screening tests
Oxalate stones in adult male or female

36. Effects CD-4 rich tissues (brain - testicles - cervix - rectum - blood vessels) - T>B
Autoimmune Antibodies found in Graves
Amino acid subgroups: Glucogenic
SCID
HIV (HTLV-1)

37. G-6- PD
Herpes Viruses
Primary Allergic Response
Maximum sinus rate
Heinz body

38. Anti - IgG
MC Nephrotic dz in kids
Job of chylomicrons
1 dose tx Vaginal Candidiasis
Autoimmune Antibodies found in Rheumatoid Arthritis

39. Mycoplasma - Chlamydia pneumonia - S. pneumonia
Mitochondrial diseases
MCC Pneumonia 18 yrs - 40 yrs
Segmented Viruses
MCC Croup & Bronchiolitis

40. CD-8 + CD-4 - Recognize MHC I - Also have markers CD-2 & CD-3
Hormones produced by the placenta
Autoimmune Antibodies found in Pemphigus Vulgaris
T- cytotoxic cells
1 dose tx Vaginal Candidiasis

41. Incubation: 4-26 wks (8 wk average) Acute dz: 4-12 wks Convalescence: 4-20 wks Recovery: yrs
Course of Hep B
T- cytotoxic cells
Places where amino acids feed in/out of TCA cycle: Acetyl CoA
Amino acid subgroups: Glucogenic

42. Restriction enzyme that cuts to the right of Met - Cys
Autoimmune Antibodies found in Drug Induced SLE
Mercaptoethanol
1 dose tx for H. ducreyi
c - abl

43. HTN - Hematuria - RBC casts
Less likely to depolarize
Cyanotic heart diseases
Nephritis Syndrome
Causes of severe monocytosis

44. Grading: severity of microscopic changes - Staging: degree of dissemination of tumor
Cancer associated with Dermatomyositis (heliotropic - malar)
Seborrheic keratosis
Subacture Bacterial Endocarditis cause & sx
Cancer Grade versus Stage

45. Affects males & females equally - Manifests in heterozygous state - Can be transmitted by either parent - Often delayed onset (adult dx) - Vertical transmission - New mutations occur in germ cells of older fathers - Can exhibit reduced penetrance & v
Methemaglobinemia chelators
Translocation 17:22
Characteristics of Autosomal Dominant Inheritance
MCC Croup & Bronchiolitis

46. S. aureus - Pseudomonas
Amino Acid deficiencies
Call - Exner body
Tyrosine Kinase
Bacteria w/ Elastase

47. 'I'D SMACK Quin' - INH - Dapsone - Sulfa drugs - Macrolides - Amiodarone - Cimetidine - Ketoconazole - Quinolones
P450 Inhibitors
Translocation 11:22
TH0 secrete
P450 Inducers

48. RSV (infants only) - Mycoplasma - Chlamydia pneumonia - S. pnuemonia
Amino acid subgroups: Gluco & Ketogenic
Blood gas w/ obstructive lung dz
S. aureus
MCC Pneumonia 6 wks - 18 yrs

49. Statins: PALS - Provostatin (only renally excreted) - Atorvastatin - Lovastatin - Simvastatin (LFTs q 3 mos) MoA: Inhibit HMG CoA reductase - most active around 8 pm - must take at night for max efficacy
Tx for Hypercholesterolemia
Dihydrofolate Reductase Inhibitors
Conditions that cause Reiter's Syndrome
Citrobacter

50. Anti - Glomerular Basement Membrane (AKA Type IV Collagen)

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