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KJZ PP Clues

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Beta1 selective: A ? M (except C&L) - Nonselective: N ? Z - C - L
Neutrophil deficiencies
Beta- Blockers
NM disease concept
Tx for 'Big Mama' anaerobes

2. Restriction enzyme that cuts to the right of Met - Cys
Amino acid subgroups: Bulky (Aromatic)
Trinucleotide repeats are found in these diseases
Mercaptoethanol
Dihydrofolate Reductase Inhibitors

3. Granulomatous (nonbacterial)
Sites of erythropoiesis
Oddities about listeria
Oxaloacetate
Cancer associated with Erythema nodosum

4. Low urine pH (2) - Hypokalemia - NO carbonic anhydrase
Type II Renal Tubular Acidosis
Risk factors for primary liver cancer
1 dose tx for H. ducreyi
Viruses related to Ca

5. Effects CD-4 rich tissues (brain - testicles - cervix - rectum - blood vessels) - T>B
HIV (HTLV-1)
Bugs with IgA Protease ( = resistant to IgA)
Comma Shaped Bugs
Drugs that trigger autoimmune hemolytic anemia

6. Anti - Myelin Receptors
Autoimmune Antibodies found in Multiple Sclerosis
Autoimmune Antibodies found in Mixed Connective Tissue Dz
Places where amino acids feed in/out of TCA cycle: a - ketoglutarate
Responsible for Bends

7. Scabies - Lichen planus - Urticaria - Dermatitis herpetiformis
Itchies rashes
Translocation 15:17
Type IV
Drug Induced SLE

8. Colon ca - pancreatic ca
CEA
Howell - Jolly body
Cystinuria
SE of Statins

9. PKU - MSUD - Cystinuria
MC COD in HIV
MCC Pneumonia 40 yrs - 65 yrs
Amino Acid deficiencies
4 causes of severe abdominal pain

10. Group B strep - E. coli - Listeria
TH1 secrete
Oxalate stones in adult female
Places where amino acids feed in/out of TCA cycle: Fumerate
MCC Meningitis 0 - 2 months

11. TPA ? aminocaproic acid - Streptokinase ? aminocaproic acid - Warfarin ? Vitamin K - Heparin ? Protamine Sulfate
Bugs that cause heart block
1 dose tx of Trichomonas
Renal Failure
Thrombolytics & rescues

12. HBcAg+ - HBsAg+ - (HBcAb +/-)
Schiller - Duvall
CVID
Acid fast organisms
Acute recent infection of Hep B

13. Anti - epidermal basement membrane protein
Nephritis Syndrome
Autoimmune Antibodies found in Bullous pemphigoid
Gram - that are strict Anaerobes
Autoimmune Antibodies found in Scleroderma

14. Gly - Ala - Ser
Places where amino acids feed in/out of TCA cycle: Pyruvate
Donovan body
MCC Pneumonia 40 yrs - 65 yrs
More likely to depolarize

15. CD-8 + CD-4 - Recognize MHC I - Also have markers CD-2 & CD-3
Pansystolic murmurs
T- cytotoxic cells
Ions responsible for different parts of the EKG
Bacteria w/ toxins that inhibit EF-2

16. SLE - endometrial & cervical cancer ? renal failure
Actions of E. coli
Enzymes ONLY seen in glycolysis
Odd MCC of Death
k - ras

17. Trypsin - Chymotrypsin - Elastase - Mercaptoethanol - Aminopeptidase - Carboxypeptidase - Cyanobromide
MCC Croup & Bronchiolitis
Gastroenteritis within 8 hours of eating
Restriction enzymes
Autoimmune Antibodies found in SLE

18. HIPPPE - Hydralazine - INH - Procainamide - Penicillamine - Phenytoin - Ethosuximide
SCID
Tx for Hypercholesterolemia
Drug Induced SLE
X- linked enzymes deficiencies

19. Troponin I: appears 2 hrs - peaks 2 days - gone 7 days - CKMB: appears 6 hrs - peaks 12 hrs - gone 2 days - LDH: appears 1 day - peaks 2 days - gone 3 days
MC Nephrotic dz in kids
MI enzymes
Causes of widened S2
Drugs that cause pulmonary fibrosis

20. Group B strep - S. pneumonia - Herpes - N. gonorrhea - Chlamydia
Disease picked up during delivery
How do you tell catalas positive Staphylococci apart?
Names of macrophages in specific tissue types: 1. Brain 2. Lung 3. Liver 4. Spleen 5. Kidney 6. LN 7. Skin 8. Bone 9. CT
Bacteria associated with colon ca

21. Mycoplasma - Nocardia (partially - gram +) - Cryptosporidium (partially - protozoa)
SCID
Acid fast organisms
Primary Allergic Response
c - myc

22. Legionella - Pneumocystis - H. pylori - Bartonella henselae - Candida
Job of IDL
Silver staining bugs
Less likely to depolarize
Timing of Immune System Response

23. Smoking
Cause of Centroacinar Emphysema
Increased susceptibility to Pseudomonas & S. aureus
Places where amino acids feed in/out of TCA cycle: Pyruvate
MCC of airway infection

24. 2nd Messenger - Smooth muscle contration by distention
Causes of Papillary Necrosis
Elevated cholesterol
Ca:Calmodulin
Ions responsible for different parts of the EKG

25. 'I'D SMACK Quin' - INH - Dapsone - Sulfa drugs - Macrolides - Amiodarone - Cimetidine - Ketoconazole - Quinolones
Conditions that cause Reiter's Syndrome
Sites of erythropoiesis
MCC Meningitis 2 mo - 10 yrs
P450 Inhibitors

26. Goodpasture's (#1) - Diabetes Mellitis - HTN - Wagner's
Zebra body
Autoimmune Antibodies found in Drug Induced SLE
Progressing to RPGN
Erythema marginatum

27. Ceftriaxone - Cefixime - Cefoxitin - Ciprofloxacin - Ofloxacin - Gatifloxicin
1 dose tx for Gonorrhea
Basal body
SE of Statins
Hormones produced by small cell ca of lung

28. Redness - itchy groin
Tinea cruris
Primary Allergic Response
Bacteria w/ toxins that inhibit EF-2
Drug Induced SLE

29. Rheumatic fever
Drugs that cause pulmonary fibrosis
Aschoff body
Herpes Viruses
Periods of rapid growth

30. Tender nodules & redness on the anterior aspect of the legs
Job of LDL
Amino acid subgroups: Bulky (Aromatic)
X- linked Dominant Inheritance diseases
Erythema nodosum

31. Necatur Americanis - Enterobius Vermicularis - Ankylostoma Duodenale - Trichuris Trichurium - Ascaris Lumbriocoides - Strongyloides
Encapsulated yeast
Essential Amino Acids
Hookwarms
SCID

32. S. saprophyticus b/c they stick things inside themselves
3 toxins of bacillus
T- cytotoxic cells
Enzymes ONLY seen in glycolysis
Most frequent cause of UTI in females 5-10 yo & 18-24 yo

33. Restrictive blood gas - Decreased pO2 - pCO2 - PCWP - Increased pH - RR - Increased risk for seizures
NM disease concept
Causes of low volume state with acidosis (not alkalosis)
Causes of Microstatosis
Job of chylomicrons

34. DNP - Free Fatty Acids
Compartment syndrome
MC COD in HIV
Rescue for active hemorhage
Electron Transport Chain Chemical Uncouplers

35. DiGeorge's - HIV
T- cell deficiencies
Dermatitis herpetiformis
Call - Exner body
Places where amino acids feed in/out of TCA cycle: Succinyl CoA

36. 0: depolarization 1: no name 2: Plateau (AV node) 3: Repolarization 4: Automaticity (SA node)
Autoimmune Antibodies found in T1DM
Enzymes ONLY seen in glycolysis
Hormones produced by small cell ca of lung
Phases of Atrial Action Potential

37. Pyruvate carboxylase - PEP carboxykinase - Fructose -1 -6- phosphatase - Glucose -6- phosphatase
3 toxins of bacillus
Enzymes NEVER seen in glycolysis
HER- II - Neu - Erb - BRCA-1 & II - p53 - CSF-1
Autoimmune Antibodies found in Celiac Sprue

38. Minimal Change Disease
Drugs that cause pulmonary fibrosis
X- linked enzymes deficiencies
Thrombolytics & rescues
MC Nephrotic dz in kids

39. Gram negative rods - Pleomorphic - 'School of fish' - Type A = non - encapsulated - non - invasive - MCC of sinusitis - otitis - bronchitis - Type B = encapsulated - invasive - IgA protease - MCC of epiglottitis
Parts of HIV viron
Most frequent cause of UTI in females 5-10 yo & 18-24 yo
Hemophilus Influenza
Drugs that cause disulfram reaction

40. High urine pH - Acidosis - Frequent UTI - Stones - Babies die <1 yr
Type I Renal Tubular Acidosis
Causes of Papillary Necrosis
Typohoid fever
Councilman body

41. BBAT - Bleomycin - Busulfan - Amiodarone - Tocainide - (methotrexate & cormustine)
Silver staining bugs
Drugs that cause pulmonary fibrosis
Second messengers
1 dose tx for Gardenella

42. S. Pneumonia - H. Influenza - Neisseria
Causes of Papillary Necrosis
Enzymes ONLY seen in glycolysis
Drugs that cause myositis
Bugs with IgA Protease ( = resistant to IgA)

43. Coumadin: Extrinsic pathway - tissue - PT - factors 2 -7 -9 -10 - PO - 8-10 hrs delay - C/I in preg - Inhib vit K dependent factor (Keep the PeT outside - extrinsic; PeT is Cujo who bites - PO) Heparin: Intrinsic - Blood - PTT - factor 3 - IV - immed
Coumadin vs Heparin
Macrophage deficiency
Cause of Centroacinar Emphysema
l - myc

44. Single aa substitution - Hereditary neuropathy - nephropathy - & cardiopathy
Characteristics of Mitochondrial Inheritance
Methemaglobinemia chelators
Autoimmune Antibodies found in Celiac Sprue
Pre - albumin/transthyretin Amyloidosis

45. 'TRiCKSSSS' - TSS (Toxic Shock) - Rocky mt spotted fever (Rickettsia) - Coxsackie A (Hand - foot - and - mouth dz) - Kawasaki - Scarlet fever (S. pyogenes) - Syphilis - Staph Scalded Skin - S. moniliformis (Reiter's syndrome)
Typohoid fever
Seborrheic keratosis
Psammoma bodies
Rashes of palm & soles

46. Rash/blisters on anterior thigh - associated with diarrhea due to Celiac Sprue flare up
Autoimmune Antibodies found in Bullous pemphigoid
Transduction
Dermatitis herpetiformis
Amino acid subgroups: Gluco & Ketogenic

47. Smoking - Alcohol - Nitrates - Japanes
Esophageal/gastric ca risk factors
Autoimmune Antibodies found in Pernicous Anemia
Bacteria w/ Elastase
MCC of airway infection

48. 1. Microglia 2. Type I pneumo 3. Kupffer 4. RES cells 5. Mesangial 6. Dendritic 7. Langerhans 8. Osteoclasts 9. Histiocytes - giant cells - epithelioid
Maximum sinus rate
Names of macrophages in specific tissue types: 1. Brain 2. Lung 3. Liver 4. Spleen 5. Kidney 6. LN 7. Skin 8. Bone 9. CT
6 Low Complement Associated Nephrotic Syndromes
Transduction

49. Adriamycin - Phen - Fen (Phentermine - fenfluramine)
Amino acid subgroups: Bulky (Aromatic)
Globoid
Drugs that cause cardic fibrosis
Seen in Rapidly Progressive GN (RPGN)

50. Osteosarcoma - glioma - fibrousarcoma
Encapsulated yeast
Parts of HIV viron
Measles
c - sis