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KJZ PP Clues

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Anti - Centromere
Autoimmune Antibodies found in CREST
Amino acid subgroups: Branched
Autoimmune Antibodies found in Vitiligo
Psoriasis

2. Sickle Cell
Amino acid subgroups: Acidic
Blood gas w/ restrictive lung dz
Heart block clue
Howell - Jolly body

3. Huntington's - Vitamin D resistant Rickets
Cancer Grade versus Stage
X- linked Dominant Inheritance diseases
Conjugation
Anterior pituitary hormones

4. Anti - Glomerular Basement Membrane (AKA Type IV Collagen)

5. 'IHOP' - Intractable pain - Hemorrhage - Obstruction - Perforation
cGMP
Indications for PUD surgery
MCC Meningitis 0 - 2 months
Characteristics of Mitochondrial Inheritance

6. Only lipoprotein to carry cholesterol - Breakdown product of VLDL
Aschoff body
Cause dysguzia
If cell mediated is defective - tx for
Job of LDL

7. Coumadin: Extrinsic pathway - tissue - PT - factors 2 -7 -9 -10 - PO - 8-10 hrs delay - C/I in preg - Inhib vit K dependent factor (Keep the PeT outside - extrinsic; PeT is Cujo who bites - PO) Heparin: Intrinsic - Blood - PTT - factor 3 - IV - immed
Functions of adhesion molecules
Coumadin vs Heparin
TH2 secrete
MCC of UTI

8. Follicular Lymphoma - bcl -2 activation
Translocation 14:18
Cancer Grade versus Stage
Oxalate stones in 5 yo black female
1 dose tx for Gonorrhea

9. TH1 - TH2
Chymotrypsin
Causes of widened S2
TH0 secrete
Indications for Pneumovax

10. Mycoplasma - Nocardia (partially - gram +) - Cryptosporidium (partially - protozoa)
Drugs that trigger autoimmune thrombocytopenia
c - myc
Pseudogout
Acid fast organisms

11. 2nd Messenger - Insulin & all growth factors
Tyrosine Kinase
Action of steroids
Cavities of blood loss
Autoimmune Antibodies found in Goodpasture's

12. Crohn's diesase
Oxalate stones in adult male or female
CVID
Staph Epidermiditis
Varicella Zoster

13. Anti - Rho - La - SSA - SSB

14. Anti - Mitochondria
Autoimmune Antibodies found in Primary Biliary Cirrhosis
Autoimmune Antibodies found in Drug Induced SLE
Pre - renal failure
cGMP

15. 'STELS' - Salmonella - TB - EBV - Listeria - Syphilis
Causes of Papillary Necrosis
Autoimmune Antibodies found in Hashimoto's
Less likely to depolarize
Causes of severe monocytosis

16. Pyruvate carboxylase - PEP carboxykinase - Fructose -1 -6- phosphatase - Glucose -6- phosphatase
Drugs that trigger autoimmune thrombocytopenia
MC Renal dz in Blacks/Hispanics
Tinea cruris
Enzymes NEVER seen in glycolysis

17. Restriction enzyme that cuts to the right of amino terminal
Macrophage deficiency
Aminopeptidase
Autoimmune Antibodies found in Myesthenia Gravis
Carcinoid triad

18. Covers MC 23 strains - Given at 2 -4 -& 6 months - Given to anyone over 65 yrs old - Given to anyone who is asplenic - Given to anyone with endo organ damage (CF - RF - Nephrotic)
Bacteria w/ toxins that inhibit EF-2
Indications for Pneumovax
Esophageal/gastric ca risk factors
Most frequent cause of UTI in females 5-10 yo & 18-24 yo

19. Grading: severity of microscopic changes - Staging: degree of dissemination of tumor
Barr Body
IP3/DAG
Cancer Grade versus Stage
Oxalate stones in 3 yo white female

20. By pigment - Aureus = gold - Epidermidis = white - Saprophyticus = none
MC Nephrotic dz in kids
Pansystolic murmurs
How do you tell catalas positive Staphylococci apart?
Autoimmune Antibodies found in CREST

21. Leu - Iso - Val
Electron Transport Chain Physical Uncouplers
Amino acid subgroups: Branched
Crescent shaped Protozoa
4 causes of severe abdominal pain

22. S. pnumoniae - Neisseria meningitides
Hormones produced by the placenta
Action of steroids
MCC Meningitis 2 mo - 10 yrs
Structures with no known function

23. In collecting duct - Absorbs ammonia in the liver - Cause of hepato - renal syndrome
Autoimmune Antibodies found in Mixed Connective Tissue Dz
Diptheria
Newborn screening tests
Glutaminase

24. Anti - Myelin Receptors
SE of thiazides & loop diuretics
PKU
Autoimmune Antibodies found in Multiple Sclerosis
'Big Mama' Anaerobes

25. Corynebacter
MCC Meningitis 10 - 21 yrs
Councilman body
n - myc
Chinese letters

26. Tender nodules & redness on the anterior aspect of the legs
MI enzymes
Hormones produced by the placenta
Chymotrypsin
Erythema nodosum

27. Cryptococcus
Drugs that cause pulmonary fibrosis
Auer Rods
Encapsulated yeast
Seborrheic keratosis

28. Colon ca - AML
Timing of Immune System Response
c - myb
Places where amino acids feed in/out of TCA cycle: Acetyl CoA
Bacteria associated with colon ca

29. Pro
Anterior pituitary hormones
Compartment syndrome
Types of kidney stones
Places where amino acids feed in/out of TCA cycle: Fumerate

30. Diabetes Hyperkalemia - NO aldosterone (infarcted JG apparatus)
Job of IDL
Tinea versicolor
Electron Transport Chain Chemical Uncouplers
Type IV

31. Job - Buckley Syn - NADPH Oxidase dfic - Neutropenia - Myeloperoxidase defic
Autoimmune Antibodies found in Goodpasture's
Tinea cruris
Neutrophil deficiencies
Macrolides

32. 'Please Check Before Going Home' - PKU - Congenital Adrenal Hyperplasia - Biotidinase - Galactosemia - Hypothyroidism
Electron Transport Chain Physical Uncouplers
Cyanotic heart diseases
Newborn screening tests
Painful Genital Lesions

33. Gene = on chr 7 - 2nd messenger is IP3/DAG - PIlocarpine can be used to treat (??)
Cystic fibrosis
X- linked Recessive Inheritance diseases
Structures with no known function
Pre - albumin/transthyretin Amyloidosis

34. Statins: PALS - Provostatin (only renally excreted) - Atorvastatin - Lovastatin - Simvastatin (LFTs q 3 mos) MoA: Inhibit HMG CoA reductase - most active around 8 pm - must take at night for max efficacy
Tx for Hypercholesterolemia
Cancer associated with Akanthosis nigricans
Encapsulated yeast
Hemophilus Influenza

35. Increased pO2 - Increased volume rt ventricle - Blood ransfusion - Supplemental O2 - Right sided heart failure - Pregnancy - IV fluids - ASD (fixed) - Deep breathing
Enzymes necessary to break down Glycogen
Pick body
Causes of widened S2
AA Amyloidosis

36. Melanoma
S-100
Councilman body
X- linked Recessive Inheritance diseases
Measles

37. Alcohol
Mercaptoethanol
Causes of Macrostatosis
MCC of newborn meningitis
Drugs that cause disulfram reaction

38. Unique N- terminal sequence - Chronic active dz - Hodgkin's dz
Lewy body
AA Amyloidosis
Primary Allergic Response
Psoriasis

39. Single aa substitution - Hereditary neuropathy - nephropathy - & cardiopathy
Low Complement Bugs
Amino acid subgroups: Acidic
Oxaloacetate
Pre - albumin/transthyretin Amyloidosis

40. Appendix - Epithalamus - Palmaris longus - Pancreatic polypeptide
Structures with no known function
MC Infection in HIV
cGMP
Elastase

41. Increased or normal pO2 - increased pCO2 - decreased pH
Translocation 14:18
Restriction enzymes
Blood gas w/ obstructive lung dz
Autoimmune Antibodies found in SLE

42. Hilum - Pelvic Brim - Entrance of bladder
3 Anatomical Narrowings of Ureter
Oxalate stones in adult female
Oddities about listeria
Glutaminase

43. Tachypnea - decreased PCO2 - pO2 - increased pH
Causes of Papillary Necrosis
Tx for 'Big Mama' anaerobes
Blood gas w/ restrictive lung dz
cAMP

44. S. saprophyticus b/c they stick things inside themselves
Progressing to RPGN
Most frequent cause of UTI in females 5-10 yo & 18-24 yo
Glutaminase
Cancer associated with Seborrheic keratosis

45. Visceral ca & end organ damage
S. aureus
Cowdry Type A body
'Big Mama' Anaerobes
Cancer associated with Akanthosis nigricans

46. 'WEPTeD' - Warfarin - Estogen - Phenytoin - Theophylline - Digoxin
MC Nephrotic dz in adults
P450 Dependent
Odd MCC of Death
c - sis

47. Heliotrope rash
Psammoma bodies
Psoriasis
Ca:Calmodulin
Dermatomyositis

48. Huntington's - Fragile X - Myotonic dystrophy - Spinal/bulbar muscular atrophy (rare)
MCC Pneumonia 6 wks - 18 yrs
Transformation
Trinucleotide repeats are found in these diseases
Autoimmune Antibodies found in Mixed Connective Tissue Dz

49. 'PIGI' - Prolactin - Inhibin - GH - Insulin
Cause of Distalacinar Emphysema
Disulfide bonds
Amino acid subgroups: Branched
Amino acid subgroups: Sulfur Bonds

50. 'BAG for CpR QTS' - Barbiturates - Alcohol - Griseofulvin - Carbamazepine - Rifampin - Quinidine - Tetracyclines - Spironolactones
MCC Meningitis 10 - 21 yrs
S. aureus
Seborrheic keratosis
P450 Inducers