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KJZ PP Clues

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Whipple's disease
Phage Mediated Toxins
Oxalate stones in adult female
Autoimmune Antibodies found in Bullous pemphigoid
MC Renal dz in Blacks/Hispanics

2. Hexokinase - Phosphofructokinase -1 - Pyruvate kinase
MCC Meningitis > 21 yrs
Tx for Cyanide poisoning
Cause of Bullous Emphysema
Enzymes ONLY seen in glycolysis

3. Normal CD4 count: 800-1200 in adults - up to 1500 in kids - < 500 begin treating w/ 2 nucleotide inhibitors & 1 protease inhibitor (750 in kids) - <200 = AIDS - add tx for PCP - <100 add tx for MAC
Hookwarms
Cystinuria
Second messengers
CD4 counts to start treatment in HIV pt

4. Strep Bovis - Bacteroides fragilis - C. melanogo - speticus - C. difficlile - If blood cx show S. bovis or C. melanogo - septicus = r/o colon ca

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5. Mitral regurg - Tricuspid regurg - VSD
Pansystolic murmurs
Anterior pituitary hormones
3 toxins of bacillus
B- cell deficiencies

6. Smoking
Cause of Centroacinar Emphysema
Enzymes NEVER seen in glycolysis
Autoimmune Antibodies found in Myesthenia Gravis
Ca++

7. 2nd Messenger - Sympathetic - catabolic - CRH
cAMP
Places where amino acids feed in/out of TCA cycle: Pyruvate
Conditions that cause Reiter's Syndrome
Trinucleotide repeats are found in these diseases

8. Pancreatitis (EtOH) - Kidney stones (bloody urine) - AAA (ripping - tearing pain) - Ischemic Bowel (bloody diarrhea)
Drugs that trigger autoimmune hemolytic anemia
Neural Crest Makes?
4 causes of severe abdominal pain
Diptheria

9. Anti - Hair Follicle
MCC of newborn meningitis
Enzymes ONLY seen in glycolysis
Autoimmune Antibodies found in Alopecia Areata
Enzymes necessary to break down Glycogen

10. Glycogen synthase - Branching enzymes: glycogen a -1 -4 glycosyl transferase - glycogen a -1 -6 glycosyl transferase
Autoimmune Antibodies found in Drug Induced SLE
Bugs with IgA Protease ( = resistant to IgA)
Enzymes necessary to make Glycogen
Neural Crest Makes?

11. Small cell carcinoma of the lung
Cancer associated with Seborrheic keratosis
Sites of erythropoiesis
l - myc
Comma Shaped Bugs

12. 'TRiCKSSSS' - TSS (Toxic Shock) - Rocky mt spotted fever (Rickettsia) - Coxsackie A (Hand - foot - and - mouth dz) - Kawasaki - Scarlet fever (S. pyogenes) - Syphilis - Staph Scalded Skin - S. moniliformis (Reiter's syndrome)
Drugs that cause pulmonary fibrosis
Crohn's d
Rashes of palm & soles
MCC Pneumonia 6 wks - 18 yrs

13. Gene = on chr 7 - 2nd messenger is IP3/DAG - PIlocarpine can be used to treat (??)
Seborrheic dermatitis
Cystic fibrosis
Amino acid subgroups: Branched
Increased susceptibility to Pseudomonas & S. aureus

14. Hypermagnesia - Hypercalcemia (except atrium) - Hypokalemia - Hypernatremia
Action of steroids
Less likely to depolarize
Job of LDL
Course of Hep B

15. Colon cancer (HIV is sudden ?)
Positive stranded RNA
Cancer associated with Seborrheic keratosis
Type II Renal Tubular Acidosis
Amino acid subgroups: Sulfur Bonds

16. Anti - smooth muscle - Anti - SCL-70
Autoimmune Antibodies found in Scleroderma
'Big Mama' Anaerobes
ret
Drugs that blast BM

17. Anti - Epidermal anchoring protein receptor - AKA Intercellular junctions of epidermal cells
Wiscott - Aldrich Syndrome (WAS)
Cancer associated with Paget's Disease
Amino Acid deficiencies
Autoimmune Antibodies found in Pemphigus Vulgaris

18. Red headed female - Tyrosine kinase deficiency
Job - Buckley Syndrome
l - myc
Silver staining bugs
Fanconi Syndrome

19. Sulfonamides - Sulfonlureas - Celecoxib (COX 2 inhibitor)
Sulfa containing drugs
n - myc
Autoimmune Antibodies found in Wegener's
B- cell deficiencies

20. Pericardium - Intracranial - Mediastinum - Pleural cavity - Thighs - Retroperitoneum - Abdominal - Pelvis
3 Anatomical Narrowings of Ureter
Herpes Viruses
Cavities of blood loss
Lead chelator

21. 'MOTEL PASS' - Melanocytes - Odontoblasts - Tracheal cartilage - Enterochromaffin cells - Laryngeal cartilage - Parafollicular cells/pseudo unipolar ceslls - All ganglia/Adrenal medulla - Schwann cells - Spiral membrane
Neural Crest Makes?
Cancer associated with Akanthosis nigricans
Cause of Distalacinar Emphysema
bcl -2

22. Toxin ADP ribosylates EF-2 - stops cell synthesis - Gram + - Acquired exotoxin from a virus via transduction - Causes heart block - Never scrape the membrane b/c it is highly vascular = will bleed & release toxin
P450 Inhibitors
IgA nephropathies
Diptheria
Autoimmune Antibodies found in Pemphigus Vulgaris

23. DiGeorge's Syndrome
AA Amyloidosis
Only immune deficiency with low calcium
Translocation 11:22
4 D's of Pellagra

24. CD-8 + CD-4 - Recognize MHC I - Also have markers CD-2 & CD-3
Call - Exner body
T- cytotoxic cells
3 Anatomical Narrowings of Ureter
Translocation 11:22

25. Gram negative rods - Pleomorphic - 'School of fish' - Type A = non - encapsulated - non - invasive - MCC of sinusitis - otitis - bronchitis - Type B = encapsulated - invasive - IgA protease - MCC of epiglottitis
Places where amino acids feed in/out of TCA cycle: Succinyl CoA
Encapsulated yeast
Hemophilus Influenza
1 dose tx for chlamydia

26. Colon ca - AML
MC Renal dz in Blacks/Hispanics
c - myb
PKU
Encapsulated Bacteria

27. PCP
MCC of newborn meningitis
MC COD in HIV
Causes of low volume state with acidosis (not alkalosis)
X- linked enzymes deficiencies

28. Portion homologous with Ig Light chain - Primary amyloidosis - multiple myeloma
6 Low Complement Associated Nephrotic Syndromes
AL Amyloidosis
How do you tell catalas positive Staphylococci apart?
Bacteria associated with colon ca

29. 'BAG for CpR QTS' - Barbiturates - Alcohol - Griseofulvin - Carbamazepine - Rifampin - Quinidine - Tetracyclines - Spironolactones
Type I Renal Tubular Acidosis
P450 Inducers
Donovan body
1 dose tx for H. ducreyi

30. CD-8 -CD-4 + - Recognize MHC II - Also have marker CD-2 & CD-3
More likely to depolarize
T- Helper cells
CD4 counts to start treatment in HIV pt
Howell - Jolly body

31. Increased pO2 - Increased volume rt ventricle - Blood ransfusion - Supplemental O2 - Right sided heart failure - Pregnancy - IV fluids - ASD (fixed) - Deep breathing
If cell mediated is defective - tx for
Places where amino acids feed in/out of TCA cycle: Fumerate
c - myc
Causes of widened S2

32. 1. S. aureus - 2. Pseudomonas
Mercaptoethanol
Cause of Bullous Emphysema
5 causes of SIADH
X- linked enzymes deficiencies

33. Cause of multiple cerebral abscesses in newborns
Essential Amino Acids
SCID
Heinz body
Citrobacter

34. Transposition of great arteries - Tetralogy of Fallot - Truncus Arteriosus - Tricuspid atresia - Total anomalous pulmonary venous return - Hypoplastic L Heart Syndrome - Ebstein's Anomaly - Aortic atresia - Pulmonary atresia
Extravasation
Secretions of Mast cells
Enzymes necessary to make Glycogen
Cyanotic heart diseases

35. Restriction enzyme that cuts to the right of Gly - Ser - Ala
Elastase
Erythema nodosum
TH1 secrete
Periods of rapid growth

36. 2nd Messenger - Smooth muscle contraction by horm/NT - All hypothatlmic hormones (except CRH)
IP3/DAG
Autoimmune Antibodies found in Polyarteritis Nodosa
Cancer associated with Erythema nodosum
Aminopeptidase

37. Fresh Frozen Plasma (FFP)
Diptheria
Rescue for active hemorhage
Donovan body
Massive Eosinophilia

38. Only lipoprotein to carry cholesterol - Breakdown product of VLDL
Ca++
Aminopeptidase
1 dose tx of Trichomonas
Job of LDL

39. 'WEPTeD' - Warfarin - Estogen - Phenytoin - Theophylline - Digoxin
P450 Dependent
Crohn's d
NM disease concept
Causes of Papillary Necrosis

40. Hypopigmented macules on the upper back in a 'V' pattern
l - myc
Tinea versicolor
Encapsulated Bacteria
Amino acid subgroups: Ketogenic

41. Defect in proximal tubule - Can't reabsorb - Low energy state - Can be caused by old tetracycline
Fanconi Syndrome
Tx for 'Big Mama' anaerobes
6 Low Complement Associated Nephrotic Syndromes
Autoimmune Antibodies found in Sjogren's

42. B2 microglobin
ret
Job of VLDL
AB Amyloidosis
Action of steroids

43. Focal Segmental GN
Amino acid subgroups: N- Bonds
MC Renal dz in Blacks/Hispanics
Esophageal/gastric ca risk factors
Secretions of Mast cells

44. Methylene blue
Methemaglobinemia chelators
Autoimmune Antibodies found in Pemphigus Vulgaris
Posterior pituitary hormones
Actions of E. coli

45. Anti - Melanocyte
Job of chylomicrons
Odd MCC of Death
Indications for Pneumovax
Autoimmune Antibodies found in Vitiligo

46. Giardia Lamblia
Amino acid subgroups: N- Bonds
Translocation 11:22
Newborn screening tests
Crescent shaped Protozoa

47. Hep B & C - Aflatoxin - Vinyl Chloride - Alcohol - Carbon Tetrachloride - Anyline dyes - Smoking - Hemochromatosis - Benzene - Schistosomiasis
Places where amino acids feed in/out of TCA cycle: Pyruvate
Macrophages
Job of IDL
Risk factors for primary liver cancer

48. Anti - Glomerular Basement Membrane (AKA Type IV Collagen)

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49. DNP - Free Fatty Acids
Trinucleotide repeats are found in these diseases
Type III Renal Tubular Acidosis
Electron Transport Chain Chemical Uncouplers
Rb

50. Myositis - Hepatitis - Increased liver enzymes
Basal body
Cowdry Type A body
Autoimmune Antibodies found in Pemphigus Vulgaris
SE of Statins