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KJZ PP Clues

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. 2nd Messenger - Smooth muscle contraction by horm/NT - All hypothatlmic hormones (except CRH)
'Big Mama' Anaerobes
IP3/DAG
Cyanide chelator
T- cytotoxic cells

2. Pyruvate carboxylase - PEP carboxykinase - Fructose -1 -6- phosphatase - Glucose -6- phosphatase
Enzymes NEVER seen in glycolysis
Maple Syrup Urine Disease (MSUD)
Causes of severe monocytosis
Erythema multiforme

3. Rash/blisters on anterior thigh - associated with diarrhea due to Celiac Sprue flare up
Massive Eosinophilia
Dermatitis herpetiformis
MC Renal Mass
Carboxypeptidase

4. Cystic Fibrosis
Oxalate stones in 3 yo white female
Roseola
Erythema marginatum
MC Infection in HIV

5. Pain (always first) - Pallor - Poikilothermia - Parasthesia - Pulselessness (always last)
Compartment syndrome
TH1 secrete
Psoriasis
Bacteria associated with colon ca

6. Follicular Lymphoma - bcl -2 activation
Translocation 14:18
Staph Epidermiditis
Basal body
Seborrheic dermatitis

7. Legionella - Pneumocystis - H. pylori - Bartonella henselae - Candida
Hemolytic properties of Strep a - Beta - ?
Bacteria associated with colon ca
Enzymes necessary to make Glycogen
Silver staining bugs

8. Crohn's diesase
Psoriasis
Oxalate stones in adult male or female
Parts of HIV viron
Auer Rods

9. Hyperglycemia - Hyperuricemia - Hypovolemia - Hypokalemia
SE of thiazides & loop diuretics
3 Anatomical Narrowings of Ureter
AA Amyloidosis
Drugs that cause pulmonary fibrosis

10. Defect in proximal tubule - Can't reabsorb - Low energy state - Can be caused by old tetracycline
Places where amino acids feed in/out of TCA cycle: Succinyl CoA
Autoimmune Antibodies found in Alopecia Areata
Fanconi Syndrome
Auer Rods

11. Herald patch - dry skin patched that follow skin lines - HHV7
HIV (HTLV-1)
Positive stranded RNA
Phage Mediated Toxins
Pityriasis rosea

12. Restriction enzyme that cuts to the right of Phe - Tyr - Trp
Chymotrypsin
1 dose tx Vaginal Candidiasis
Neutrophil deficiencies
Electron Transport Chain Physical Uncouplers

13. Methyl malonyl CoA mutase - Homocysteine methyl transferase
TH1 secrete
Cavities of blood loss
Enzymes used by B12
4 D's of Pellagra

14. Anti - Gliaden/gluten
Autoimmune Antibodies found in Celiac Sprue
Pre - renal failure
Type III Renal Tubular Acidosis
MCC of airway infection

15. Asp - Glu
Cancer associated with Dermatomyositis (heliotropic - malar)
Amino acid subgroups: Acidic
k - ras
Erythema multiforme

16. Flushing - Wheezing - Diarrhea - Tx with ciproheptadine - dx by measuring 5- HIAA in the urine - Most common primary location = appendix - Most common metastaic location = pancreas - ileum
Primary Allergic Response
Job of chylomicrons
1 dose tx for Gardenella
Carcinoid triad

17. VSD - ASD - PDA - Coarctation of aorta
Names of macrophages in specific tissue types: 1. Brain 2. Lung 3. Liver 4. Spleen 5. Kidney 6. LN 7. Skin 8. Bone 9. CT
Causes of low volume state with acidosis (not alkalosis)
MC Non - cyanotic congenital heart dz
Oxaloacetate

18. Smoking - Aniline dyes - Benzene - Aflatoxin - Cyclophosphamie - Schistosomiasis - Von Hippel - Lindau - Tuberous sclerosis
Bladder ca risk factors
6 Low Complement Associated Nephrotic Syndromes
Disulfide bonds
Used for Cold Agglutinin Testing

19. 1. S. aureus - 2. Pseudomonas
Bugs that cause heart block
Translocation 11:22
Cause of Bullous Emphysema
Autoimmune Antibodies found in Pemphigus Vulgaris

20. HPV = cervical ca - EBV = lymphoma - HVB - HVC = liver ca - HIV = Kaposi
Autoimmune Antibodies found in Sjogren's
1 dose tx for Gonorrhea
Anterior pituitary hormones
Viruses related to Ca

21. Anti - Topoisomerase
B Vitamins
k - ras
TH1 secrete
Autoimmune Antibodies found in Progressive Systemic Sclerosis

22. Anti - Myelin Receptors
Tinea cruris
Autoimmune Antibodies found in Multiple Sclerosis
Names of macrophages in specific tissue types: 1. Brain 2. Lung 3. Liver 4. Spleen 5. Kidney 6. LN 7. Skin 8. Bone 9. CT
Posterior pituitary hormones

23. 'I AM HE' - Influenza - Adenovirus - Mycoplasma - Hep B & C - EBV
Macrophage deficiency
Rashes of palm & soles
Less likely to depolarize
Low Complement Bugs

24. 'Please Check Before Going Home' - PKU - Congenital Adrenal Hyperplasia - Biotidinase - Galactosemia - Hypothyroidism
MC COD in HIV
Newborn screening tests
Causes of Macrostatosis
Job - Buckley Syndrome

25. CD-8 + CD-4 - Recognize MHC I - Also have markers CD-2 & CD-3
T- cytotoxic cells
Trypsin
Subacture Bacterial Endocarditis cause & sx
Drug Induced SLE

26. Complex I - Amytal - Rotenone - Complex II - Malonate - Complex III - Antimycin - Complex IV - CN - CO - Chloramphenicol - Complex V - Oligomycin
Electron Transport Chain Poisons
Seborrheic dermatitis
Most frequent cause of UTI in females 5-10 yo & 18-24 yo
Amino acid subgroups: Bulky (Aromatic)

27. Phenylalanine hydroxylase deficiency - Needed to make tyrosine - Leads to a lack of Dopamine - Epi - Norepi - melanin
Only immune deficiency with low calcium
PKU
MC Renal Dz in HIV/drug users
Cystinuria

28. Only gram + w/ endotoxin - Crosses placenta - Lipid A is toxic part - Causes granulomas - Causes sepsis in neonates - Raw cabbage - spoiled milk
Amino acid subgroups: Bulky (Aromatic)
Oddities about listeria
If cell mediated is defective - tx for
P450 Dependent

29. MCC of osteomyelitis - MCC of infection in burn pts
Drugs that blast BM
MCC Pneumonia 6 wks - 18 yrs
1 dose tx for chlamydia
S. aureus

30. Group B strep - S. pneumonia - Herpes - N. gonorrhea - Chlamydia
Erythema chronicum migrans
Disease picked up during delivery
Itchies rashes
T- cell deficiencies

31. Deletion of chr 22 - Problem with 3rd & 4th pharyngeal pouches - Hypokalemia

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32. Gly - Ala - Ser
MCC Meningitis > 21 yrs
Howell - Jolly body
Places where amino acids feed in/out of TCA cycle: Pyruvate
Cause dysguzia

33. Measles - Mumps - Rubella - Oral polio - Rotavirus - Smallpox - BCG (TB vaccine) - Yellow fever - Varicella
Autoimmune Antibodies found in Progressive Systemic Sclerosis
9 live vaccines
Scabies
Aschoff body

34. Vasculities - AIDS
Causes of widened S2
Causes of Papillary Necrosis
Bacteria w/ toxins that inhibit EF-2
Responsible for Bends

35. 'TRiCKSSSS' - TSS (Toxic Shock) - Rocky mt spotted fever (Rickettsia) - Coxsackie A (Hand - foot - and - mouth dz) - Kawasaki - Scarlet fever (S. pyogenes) - Syphilis - Staph Scalded Skin - S. moniliformis (Reiter's syndrome)
Places where amino acids feed in/out of TCA cycle: a - ketoglutarate
MCC of airway infection
Rashes of palm & soles
Used for Cold Agglutinin Testing

36. Alcohol
Bacteria w/ Elastase
MCC Meningitis 2 mo - 10 yrs
Cyanotic heart diseases
Causes of Macrostatosis

37. Redness - itchy groin
Causes of severe monocytosis
Tinea cruris
MCC Pneumonia 18 yrs - 40 yrs
Neutrophil deficiencies

38. DNP - Free Fatty Acids
Electron Transport Chain Chemical Uncouplers
Urease positive bacteria
Action of steroids
Functions of adhesion molecules

39. Celiac Sprue
Oxalate stones in 5 yo black female
Tx for 'Big Mama' anaerobes
Cause of Bullous Emphysema
Cyanotic heart diseases

40. S. pneumonia
Schiller - Duvall
Enzymes necessary to make Glycogen
MCC Meningitis > 21 yrs
Hemophilus Influenza

41. 'WEPTeD' - Warfarin - Estogen - Phenytoin - Theophylline - Digoxin
MCC Pneumonia 40 yrs - 65 yrs
Job of chylomicrons
P450 Dependent
Cause of Distalacinar Emphysema

42. 'IHOP' - Intractable pain - Hemorrhage - Obstruction - Perforation
c - abl
Ca++
Indications for PUD surgery
Periods of rapid growth

43. Colon cancer (HIV is sudden ?)
Cancer associated with Seborrheic keratosis
Drugs that cause disulfram reaction
Odd MCC of Death
Conditions that cause Reiter's Syndrome

44. (Sinusitis - otitis - bronchitis - pneumonia) 1. S. pneumonia 2. H. influenza 3. N. meningitides
T&B cell deficiencies
Elevated cholesterol
MCC of airway infection
T- cytotoxic cells

45. Edema - Hyperlipidemia - Hypercholesterolemia - Hypercoagulability - serum albumin - urine albumin
Autoimmune Antibodies found in Primary Biliary Cirrhosis
Types of kidney stones
Nephrotic Syndrome
Bugs that cause heart block

46. Anti - Mitochondria
Causes of widened S2
T&B cell deficiencies
Autoimmune Antibodies found in Primary Biliary Cirrhosis
MC Nephrotic dz in kids

47. Herpes
Cowdry Type A body
AL Amyloidosis
Enzymes NEVER seen in glycolysis
B Vitamins

48. MCC all throat infections - lymphangitis - impetigo - necrotizing fascitis - erysipelas - scarlet fever - 2nd MCC: all other skin infections
1 dose tx Vaginal Candidiasis
Job of LDL
Strep Pyogenes
Autoimmune Antibodies found in Vitiligo

49. 'I'D SMACK Quin' - INH - Dapsone - Sulfa drugs - Macrolides - Amiodarone - Cimetidine - Ketoconazole - Quinolones
Autoimmune Antibodies found in CREST
cGMP
MCC Meningitis 2 mo - 10 yrs
P450 Inhibitors

50. Decreased: K - Na - Cl - increased: pH - BP
Strep Pyogenes
Causes of low volume state with acidosis (not alkalosis)
Job - Buckley Syndrome
Serum Values for Low Volume State