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KJZ PP Clues

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Herpes - Chancroid (H. ducreyi) - Lymphogranuloma venereum - Lymphogramuloma inguinale
TH1 secrete
Painful Genital Lesions
Measles
Nephrotic Syndrome

2. S. Pneumonia - Viruses - Anaerobes - H. influenza - Gram negative rods
Electron Transport Chain Physical Uncouplers
Oxalate stones in 5 yo black female
MCC Pneumonia in Elderly
IgA nephropathies

3. Scaly skin w/ oily skin on the hairline
Typohoid fever
Seborrheic dermatitis
Macrophage deficiency
Characteristics of Mitochondrial Inheritance

4. Rash/blisters on anterior thigh - associated with diarrhea due to Celiac Sprue flare up
Bacteria w/ toxins that inhibit EF-2
MCC Pneumonia 6 wks - 18 yrs
Heart block clue
Dermatitis herpetiformis

5. Cystic Fibrosis - Closed angle glaucoma
Uses for Pilocarpine
S-100
c - myb
Typohoid fever

6. Asn - Gln
Progressing to RPGN
Amino acid subgroups: N- Bonds
Massive Eosinophilia
Viruses related to Ca

7. 1st Contact - Neutrophils work first 3 days - Then B- cells make IgM - peaks at 14 days - gone in 2 mos - IgG shows up at 2 weeks - peaks in 2 mos - gone in 1 yr
Drugs that trigger autoimmune thrombocytopenia
AE Amyloidosis
Encapsulated yeast
Primary Allergic Response

8. HBcAg+ - HBsAg+ - (HBcAb +/-)
Negative stranded RNA
Autoimmune Antibodies found in Sjogren's
MCC of newborn meningitis
Acute recent infection of Hep B

9. Focal Segmental GN
MCC Pneumonia in Elderly
MC Renal Dz in HIV/drug users
TH1 secrete
SCID

10. Restriction enzyme that cuts to the left of carboxy terminal
Enzymes necessary to make Glycogen
Macrophage deficiency
Gram - that are strict Anaerobes
Carboxypeptidase

11. Toxin ADP ribosylates EF-2 - stops cell synthesis - Gram + - Acquired exotoxin from a virus via transduction - Causes heart block - Never scrape the membrane b/c it is highly vascular = will bleed & release toxin
Cancer Grade versus Stage
Diptheria
Increased susceptibility to Pseudomonas & S. aureus
Oxalate stones in 3 yo white female

12. Huntington's - Vitamin D resistant Rickets
Crohn's d
Hemolytic properties of Strep a - Beta - ?
1 dose tx for H. ducreyi
X- linked Dominant Inheritance diseases

13. 'Some Strange Killers Have Pretty Nice Capsules' - Strep. pneumo (gr +) - Salmonella - Klebsiella - H. Flu B - Pseudomonas - Neisseria - Citrobacter
MCC of airway infection
Action of steroids
Autoimmune Antibodies found in Mixed Connective Tissue Dz
Encapsulated Bacteria

14. Phenylalanine hydroxylase deficiency - Needed to make tyrosine - Leads to a lack of Dopamine - Epi - Norepi - melanin
Measles
PKU
Macrolides
Characteristics of Autosomal Recessive Inheritance

15. Viral - Fungal - Mycobacterium - Protozoa - Parasite - Neoplasm
Varicella Zoster
If cell mediated is defective - tx for
Lead chelator
Autoimmune Antibodies found in Hashimoto's

16. Ovarian tumor
B Vitamins
Macrolides
Encapsulated yeast
Call - Exner body

17. Defect in proximal tubule - Can't reabsorb - Low energy state - Can be caused by old tetracycline
Fanconi Syndrome
Disease picked up during delivery
Methotrexate uses
c - abl

18. Heart: PDA - Elbow: dialysis fistula - Brain: Von Hippel - Lindau - Lungs: Osler - Weber - Rendu
AVMs machinery murmur
Risk factors for primary liver cancer
Rashes of palm & soles
Job of IDL

19. Metronidazole
Translocation 15:17
Macrolides
1 dose tx for Gardenella
Amino acid subgroups: Acidic

20. Fever for 2 days than rash pops up (rash only after fever is gone) - HHV 6
Type II Renal Tubular Acidosis
Thrombolytics & rescues
Roseola
4 D's of Pellagra

21. Metronidazole
c - sis
When does minimal change dz occur?
Salmonella typhi
1 dose tx of Trichomonas

22. Pain (always first) - Pallor - Poikilothermia - Parasthesia - Pulselessness (always last)
Compartment syndrome
Autoimmune Antibodies found in Pernicous Anemia
Psoriasis
Acute recent infection of Hep B

23. Scabies - Lichen planus - Urticaria - Dermatitis herpetiformis
MC Renal Dz in HIV/drug users
Secretions of Mast cells
Itchies rashes
Actions of E. coli

24. Methylene blue
Methemaglobinemia chelators
Cyanide chelator
Responsible for Bends
Characteristics of Autosomal Recessive Inheritance

25. 2nd Messenger - Nitrates - Viagra - ANP & LPS
Second messengers
Oddities about listeria
NO
Roseola

26. Unique N- terminal sequence - Chronic active dz - Hodgkin's dz
AA Amyloidosis
Type I Renal Tubular Acidosis
Conjugation
Drugs that cause myositis

27. Parkinsons
Lewy body
Itchies rashes
Russell body
Pre - albumin/transthyretin Amyloidosis

28. CD-8 -CD-4 + - Recognize MHC II - Also have marker CD-2 & CD-3
Aschoff body
Functions of adhesion molecules
Increased susceptibility to Pseudomonas & S. aureus
T- Helper cells

29. Legionella - Pneumocystis - H. pylori - Bartonella henselae - Candida
Silver staining bugs
Anterior pituitary hormones
Positive stranded RNA
Encapsulated Bacteria

30. DNP - Free Fatty Acids
Bacteria w/ Elastase
T&B cell deficiencies
Barr Body
Electron Transport Chain Chemical Uncouplers

31. Azithromycin - Clarithromycin - Erythromycin
Autoimmune Antibodies found in CREST
Type IV
1 dose tx of candidiasis
Macrolides

32. Only lipoprotein to carry cholesterol - Breakdown product of VLDL
Tx for 'Big Mama' anaerobes
Seborrheic keratosis
Job of LDL
Enzymes used by B12

33. Statins: PALS - Provostatin (only renally excreted) - Atorvastatin - Lovastatin - Simvastatin (LFTs q 3 mos) MoA: Inhibit HMG CoA reductase - most active around 8 pm - must take at night for max efficacy
Pityriasis rosea
l - myc
Tx for Hypercholesterolemia
Positive stranded RNA

34. MEN II - MEN III
Coumadin vs Heparin
ret
MCC Meningitis 2 mo - 10 yrs
Oxalate stones in 3 yo white female

35. Alcohol
Electron Transport Chain Chemical Uncouplers
Methemaglobinemia chelators
Cancer associated with Akanthosis nigricans
Causes of Macrostatosis

36. Serum Sickness - SLE - SBE - PSGN - MPGN II - Cryoglobulinemia
6 Low Complement Associated Nephrotic Syndromes
Drugs that cause myositis
Drugs that cause cardic fibrosis
P450 Dependent

37. Plasma (RTA) - Ammonia production in the collection duct - 10% of urea cycle - Glutaminase - Carbonic anhydrase
1 dose tx of Trichomonas
4 sources of renal acid
MI enzymes
Chymotrypsin

38. Cystathione synthase deficiency - Cysteine - ornithine - lysine - and arginine end up in urine - stones
Job of IDL
Cystinuria
Seborrheic keratosis
Pre - renal failure

39. Only gram + w/ endotoxin - Crosses placenta - Lipid A is toxic part - Causes granulomas - Causes sepsis in neonates - Raw cabbage - spoiled milk
Massive Eosinophilia
Cancer associated with Paget's Disease
Carboxypeptidase
Oddities about listeria

40. Yolk sac tumor
Heart block clue
Electron Transport Chain Chemical Uncouplers
Hormones produced by the placenta
Schiller - Duvall

41. 4 mos gestation = Yolk Sac - 6 mos gestation = Spleen - liver - flat bones - 8 mos gestation = Long bones - If long bones become damaged the spleen can take over - resulting in splenomegaly
Sites of erythropoiesis
Cyanobromide
Gram - that are strict Anaerobes
MCC Croup & Bronchiolitis

42. Tyrosine kinase deficiency - Late onset - Frameshift/missense mutation
CVID
X- linked enzymes deficiencies
Massive Eosinophilia
Restriction enzymes

43. MC infection of shunts & central lines
Staph Epidermiditis
Cancer associated with Akanthosis nigricans
Roseola
Psammoma bodies

44. Memory - IgG shows up at day 3 with 5x the concentration - Highest affinity for antigen - Peaks in 5 years - stays for 10 years
Macrophage deficiency
Hookwarms
Secondary Allergic response
5 causes of SIADH

45. Phe - Iso - Thr - Trp
Phage Mediated Toxins
Chymotrypsin
Amino acid subgroups: Gluco & Ketogenic
Translocation 11:14

46. Small cell carcinoma of the lung
B- cell deficiencies
Anterior pituitary hormones
Pulmonary Infiltrate w/ Eosinophilia
l - myc

47. Sulfonamides - Sulfonlureas - Celecoxib (COX 2 inhibitor)
Rashes of palm & soles
Drug Induced SLE
Sulfa containing drugs
Autoimmune Antibodies found in Rheumatoid Arthritis

48. Follicular Lymphoma - bcl -2 activation
Places where amino acids feed in/out of TCA cycle: a - ketoglutarate
Translocation 14:18
Nephritis Syndrome
Autoimmune Antibodies found in Bullous pemphigoid

49. Adriamycin - Phen - Fen (Phentermine - fenfluramine)
Seen in Rapidly Progressive GN (RPGN)
Drugs that cause cardic fibrosis
Action of steroids
Drugs that trigger autoimmune hemolytic anemia

50. 2nd Messenger - Parasympathetic - anabolic
MCC Meningitis > 21 yrs
cGMP
MC Non - cyanotic congenital heart dz
Structures with no known function