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KJZ PP Clues

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Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Statins: PALS - Provostatin (only renally excreted) - Atorvastatin - Lovastatin - Simvastatin (LFTs q 3 mos) MoA: Inhibit HMG CoA reductase - most active around 8 pm - must take at night for max efficacy
Beta- Blockers
Tx for Hypercholesterolemia
X- linked enzymes deficiencies
Oxalate stones in 5 yo black female

2. Focal Segmental GN
Drugs that trigger autoimmune hemolytic anemia
MC Renal Dz in HIV/drug users
Acute recent infection of Hep B
Autoimmune Antibodies found in Bullous pemphigoid

3. Covers MC 23 strains - Given at 2 -4 -& 6 months - Given to anyone over 65 yrs old - Given to anyone who is asplenic - Given to anyone with endo organ damage (CF - RF - Nephrotic)
MC Renal dz in Blacks/Hispanics
Indications for Pneumovax
9 live vaccines
Uses for Pilocarpine

4. Troponin I: appears 2 hrs - peaks 2 days - gone 7 days - CKMB: appears 6 hrs - peaks 12 hrs - gone 2 days - LDH: appears 1 day - peaks 2 days - gone 3 days
MI enzymes
Bladder ca risk factors
Serum Values for Low Volume State
Staph Epidermiditis

5. Yolk sac tumor
Rescue for active hemorhage
Schiller - Duvall
S. aureus
Autoimmune Antibodies found in Alopecia Areata

6. Deletion of chr 22 - Problem with 3rd & 4th pharyngeal pouches - Hypokalemia

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7. Chlorpropamide - Lactams - Antabuse - Metronidazole
Amino acid subgroups: N- Bonds
Tx for Hypercholesterolemia
Less likely to depolarize
Drugs that cause disulfram reaction

8. Anti - Smith - - dsDNA (most nephrotoxic) - Cardiolipin (clotting - bleeding - false VRDL)
Autoimmune Antibodies found in SLE
Wiscott - Aldrich Syndrome (WAS)
Gram - that are strict Anaerobes
Mitochondrial diseases

9. Adenocarcinoma
Restriction enzymes
MCC Meningitis 2 mo - 10 yrs
Segmented Viruses
MC Malignant Renal tumor in adults

10. I sprayed ORTHO on a BUNYA at the AreNA down in REO to kill SEGMENTED worms' - Orthovirdiae - Bunyavirdiae - Arenavirdiae - Reovirdiae
Amino acid subgroups: Smallest
Autoimmune Antibodies found in SLE
Segmented Viruses
Silver staining bugs

11. Toxin ADP ribosylates EF-2 - stops cell synthesis - Gram + - Acquired exotoxin from a virus via transduction - Causes heart block - Never scrape the membrane b/c it is highly vascular = will bleed & release toxin
Pulmonary Infiltrate w/ Eosinophilia
MC Renal Mass
Indications for PUD surgery
Diptheria

12. Fresh Frozen Plasma (FFP)
Disulfide bonds
Ca++
Rescue for active hemorhage
Pick body

13. Pancreatitis (EtOH) - Kidney stones (bloody urine) - AAA (ripping - tearing pain) - Ischemic Bowel (bloody diarrhea)
Places where amino acids feed in/out of TCA cycle: Succinyl CoA
4 causes of severe abdominal pain
X- linked Dominant Inheritance diseases
Parts of HIV viron

14. Shigella - Salmonella - Yersinia - Crohn's - IBD - Chlamydia - C. jejuni

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15. High urine pH - Acidosis - Frequent UTI - Stones - Babies die <1 yr
Type I Renal Tubular Acidosis
T- cell deficiencies
If cell mediated is defective - tx for
Blood gas w/ obstructive lung dz

16. (For rheumatic fever) - Polyarthritis (joints) - Carditis (<3) - Nodules subcutaneous - Erythema marginatum - Sydenham chorea
Jones Criteria (J<3NES)
Elevated TGs
PKU
Pick body

17. Cys - Met
Amino acid subgroups: Sulfur Bonds
Places where amino acids feed in/out of TCA cycle: Fumerate
Cause dysguzia
Erythema multiforme

18. 'KIISS' - Kills T- cells & eosinophils - Inhibit macrophage migration - Inhibit phospholipase A - Inhibit mast cell degranulation - Stabilizes endothelium - Stimulates protein synthesis
Amino acid subgroups: Acidic
Causes of low volume state with acidosis (not alkalosis)
Action of steroids
MCC Meningitis 0 - 2 months

19. Henoch - Schoenlein Purpura (HSP) - Berger's - Alport's - Ankylosing Spondylitis
Crescent shaped Protozoa
Trypsin
Oxalate stones in 3 yo white female
IgA nephropathies

20. Parainfluenza - RSV (ER this is #1) - Adenovirus - Influenza
TH0 secrete
MCC Pneumonia 40 yrs - 65 yrs
Names of macrophages in specific tissue types: 1. Brain 2. Lung 3. Liver 4. Spleen 5. Kidney 6. LN 7. Skin 8. Bone 9. CT
MCC Croup & Bronchiolitis

21. Sickle Cell
Howell - Jolly body
Autoimmune Antibodies found in CREST
Segmented Viruses
Conditions that cause Reiter's Syndrome

22. Anti - Histone
Renal Failure
Causes of widened S2
Autoimmune Antibodies found in Drug Induced SLE
Segmented Viruses

23. Cryptococcus
Encapsulated yeast
Drug Induced SLE
1 dose tx of candidiasis
Enzymes necessary to break down Glycogen

24. Burn pts - Cystic fibrosis - Diabetes - Neutropenics
Serum Values for Low Volume State
4 D's of Pellagra
Characteristics of Mitochondrial Inheritance
Increased susceptibility to Pseudomonas & S. aureus

25. Takes triglycerides from liver to adipose - Only made in the liver - Breaks down into IDL + LDL
Job of VLDL
Transduction
Dihydrofolate Reductase Inhibitors
Macrolides

26. Restriction enzyme that cuts to the right of Met - Cys
Autoimmune Antibodies found in SLE
Mercaptoethanol
c - abl
AE Amyloidosis

27. Restriction enzyme that cuts to the right of amino terminal
Aminopeptidase
1 dose tx for H. ducreyi
Causes of Macrostatosis
Cavities of blood loss

28. Ca pyrophosphate - + birefringent crystals - rhomboid crystals - MC older pts - Seen equally in both genders - tx = colchicine
X- linked Dominant Inheritance diseases
Amino acid subgroups: Ketogenic
Pseudogout
Rb

29. Target lesion - bullseye - Lyme dz
4 sources of renal acid
Erythema chronicum migrans
TH0 secrete
Macrophages

30. Hyperglycemia - Hyperuricemia - Hypovolemia - Hypokalemia
Wiscott - Aldrich Syndrome (WAS)
Auer Rods
Hookwarms
SE of thiazides & loop diuretics

31. Metronidazole - Clindamycin - Cefoxitin

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32. 'SIADH' - Small cell ca - Increased Intracranial Pressure - A Pain - Drugs - Hypoxia
Type IV
Course of Hep B
5 causes of SIADH
1 dose tx for Gonorrhea

33. 'IHOP' - Intractable pain - Hemorrhage - Obstruction - Perforation
P450 Inhibitors
TH1 secrete
Autoimmune Antibodies found in Progressive Systemic Sclerosis
Indications for PUD surgery

34. Hypermagnesia - Hypercalcemia (except atrium) - Hypokalemia - Hypernatremia
Maple Syrup Urine Disease (MSUD)
Less likely to depolarize
Indications for Pneumovax
Cause of Distalacinar Emphysema

35. Increased or normal pO2 - increased pCO2 - decreased pH
Amino acid subgroups: N- Bonds
Cancer associated with Actinic keratosis
Blood gas w/ obstructive lung dz
Coumadin vs Heparin

36. Transposition of great arteries - Tetralogy of Fallot - Truncus Arteriosus - Tricuspid atresia - Total anomalous pulmonary venous return - Hypoplastic L Heart Syndrome - Ebstein's Anomaly - Aortic atresia - Pulmonary atresia
Cyanotic heart diseases
Causes of Macrostatosis
Cystinuria
More likely to depolarize

37. Hypopigmented macules on the upper back in a 'V' pattern
Tinea versicolor
Methotrexate uses
Conjugation
Viruses related to Ca

38. Asn - Gln
Zebra body
MCC Meningitis 10 - 21 yrs
Amino acid subgroups: N- Bonds
Cancer associated with urticaria (hives)

39. Membranous GN
Risk factors for primary liver cancer
Blood gas w/ restrictive lung dz
MC Nephrotic dz in adults
Used for Cold Agglutinin Testing

40. Melanoma
Autoimmune Antibodies found in Drug Induced SLE
Hemolytic properties of Strep a - Beta - ?
S-100
PKU

41. 'NAACP' - Neoplasms - Allergies/asthma - Addison's - Collagen Vascular dz - Parasites
Massive Eosinophilia
Gram + Spore formers
Responsible for Bends
Coumadin vs Heparin

42. Wiskott - Aldrich Syndrome (WAS) - SCID - CVID - HIV (HTLV-1) - Job - Buckley Syndrome
1 dose tx for H. ducreyi
Carboxypeptidase
T&B cell deficiencies
Viruses related to Ca

43. Methyl malonyl CoA mutase - Homocysteine methyl transferase
Course of Hep B
1 dose tx for chlamydia
Enzymes used by B12
Types of kidney stones

44. Herald patch - dry skin patched that follow skin lines - HHV7
MCC Meningitis 10 - 21 yrs
Pityriasis rosea
Drugs that cause disulfram reaction
Macrolides

45. HIPPPE - Hydralazine - INH - Procainamide - Penicillamine - Phenytoin - Ethosuximide
Blood gas w/ restrictive lung dz
Drug Induced SLE
Primary Allergic Response
Cancer associated with Paget's Disease

46. ADH (supraoptic nucleus) - Oxytocin (paraventricular nucleus)
Most frequent cause of UTI in females 5-10 yo & 18-24 yo
Disulfide bonds
Places where amino acids feed in/out of TCA cycle: Fumerate
Posterior pituitary hormones

47. Xanthanthomas on extensor surfaces - Increased risk for CAD
Characteristics of Autosomal Recessive Inheritance
Enzymes NEVER seen in glycolysis
Electron Transport Chain Poisons
Elevated cholesterol

48. DNP - Free Fatty Acids
MI enzymes
Heinz body
Electron Transport Chain Chemical Uncouplers
Elevated cholesterol

49. Cystathione synthase deficiency - Cysteine - ornithine - lysine - and arginine end up in urine - stones
T&B cell deficiencies
Erythema chronicum migrans
If cell mediated is defective - tx for
Cystinuria

50. Myositis - Hepatitis - Increased liver enzymes
Globoid
Hemophilus Influenza
SE of Statins
Itchies rashes