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KJZ PP Clues

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Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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1. Anti - Hair Follicle
cGMP
MCC of newborn meningitis
Tinea cruris
Autoimmune Antibodies found in Alopecia Areata

2. Cystathione synthase deficiency - Cysteine - ornithine - lysine - and arginine end up in urine - stones
Trinucleotide repeats are found in these diseases
AVMs machinery murmur
Second messengers
Cystinuria

3. Silvery white plaques on extensor surfaces - scaly skin - pitted nails
Encapsulated Bacteria
Psoriasis
Job - Buckley Syndrome
Transformation

4. Pancreatitis (EtOH) - Kidney stones (bloody urine) - AAA (ripping - tearing pain) - Ischemic Bowel (bloody diarrhea)
Action of steroids
Zebra body
Autoimmune Antibodies found in Wegener's
4 causes of severe abdominal pain

5. Troponin I: appears 2 hrs - peaks 2 days - gone 7 days - CKMB: appears 6 hrs - peaks 12 hrs - gone 2 days - LDH: appears 1 day - peaks 2 days - gone 3 days
Thrombolytics & rescues
X- linked Dominant Inheritance diseases
MI enzymes
Amino acid subgroups: Glucogenic

6. Hypermagnesia - Hypercalcemia (except atrium) - Hypokalemia - Hypernatremia
T&B cell deficiencies
Citrobacter
Less likely to depolarize
Secondary Allergic response

7. Osteosarcoma - glioma - fibrousarcoma
c - sis
Erythema nodosum
AP amyloidosis
Psammoma bodies

8. PPUNCHeS - Proteus - Pseudomonas - Ureaplsma urealyticum - Nocardia - Cryptococcus neoformans - H. pylori - S. Saprofiticus
Translocation 9:22
1 dose tx of candidiasis
1 dose tx for Gonorrhea
Urease positive bacteria

9. Universally associated with all amyloids
DiGeorge's
AP amyloidosis
c - myb
Cowdry Type A body

10. Calcium oxalate (80%) - Struvite - Uric Acid - Cysteine - Oxalate
AA Amyloidosis
Types of kidney stones
Odd MCC of Death
Autoimmune Antibodies found in Celiac Sprue

11. < 24 hrs: swelling - @ 24 hrs: neutrophils show up - Day 3: neutrophils peak - Day 4: T- cells & macrophages show up - Day 7: Fibroblasts show up - 1 month: Fibroblasts peak - 3-6 months: Fibroblasts are gone
Timing of Immune System Response
Encapsulated Bacteria
Lead chelator
Amino acid subgroups: N- Bonds

12. 1st Contact - Neutrophils work first 3 days - Then B- cells make IgM - peaks at 14 days - gone in 2 mos - IgG shows up at 2 weeks - peaks in 2 mos - gone in 1 yr
Primary Allergic Response
Roseola
MCC Meningitis 0 - 2 months
Oxaloacetate

13. Effects CD-4 rich tissues (brain - testicles - cervix - rectum - blood vessels) - T>B
Cancer Grade versus Stage
HIV (HTLV-1)
Auer Rods
Amino acid subgroups: N- Bonds

14. Dermatitis - Diarrhea - Dementia - Death

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15. 'Fabry & Lesh go Hunting for Candy - Pie - & Gum' - Fabry's - Lesh - Nyhan - G6PD - CGD (NADPH) - Pyruvate DH
Responsible for Bends
9 live vaccines
DiGeorge's
X- linked enzymes deficiencies

16. <20 = normal - 30-60 = heterozygous for CF - > 60 definitive positive
4 sources of renal acid
Enzymes used by B12
cAMP
Sweat test

17. Ca pyrophosphate - + birefringent crystals - rhomboid crystals - MC older pts - Seen equally in both genders - tx = colchicine
Pseudogout
Citrobacter
Bacteria associated with colon ca
ret

18. Hypopigmented macules on the upper back in a 'V' pattern
Job of IDL
Tinea versicolor
Causes of Microstatosis
Bacteria w/ toxins that inhibit EF-2

19. Ewing's Sarcoma - 11 = long bones
Functions of adhesion molecules
Amino acid subgroups: Sulfur Bonds
Autoimmune Antibodies found in Vitiligo
Translocation 11:22

20. Anti - Mitochondria
4 D's of Pellagra
IP3/DAG
Autoimmune Antibodies found in Primary Biliary Cirrhosis
Bacteria associated with colon ca

21. S. Pneumonia - H. Influenza - Neisseria
Type II Renal Tubular Acidosis
Bugs with IgA Protease ( = resistant to IgA)
Autoimmune Antibodies found in Vitiligo
Drugs that blast BM

22. Rose spots associated w/ 'intestinal fire -' Salmonella Typhi
Typohoid fever
ret
Esophageal/gastric ca risk factors
c - myb

23. H. flue - Neisseria
Amino acid subgroups: Basic
Gram - that are strict Anaerobes
Causes of Microstatosis
Barr Body

24. Leishmaniasis
Donovan body
Autoimmune Antibodies found in Drug Induced SLE
MI enzymes
cAMP

25. Pro
Places where amino acids feed in/out of TCA cycle: Fumerate
Characteristics of Autosomal Recessive Inheritance
Cancer associated with Actinic keratosis
Staph Epidermiditis

26. Restrictive blood gas - Decreased pO2 - pCO2 - PCWP - Increased pH - RR - Increased risk for seizures
Amino acid subgroups: Gluco & Ketogenic
k - ras
NM disease concept
Causes of Microstatosis

27. Pain (always first) - Pallor - Poikilothermia - Parasthesia - Pulselessness (always last)
Trypsin
Autoimmune Antibodies found in Drug Induced SLE
Compartment syndrome
Type III Renal Tubular Acidosis

28. Grading: severity of microscopic changes - Staging: degree of dissemination of tumor
Cancer Grade versus Stage
Comma Shaped Bugs
AB Amyloidosis
Gram + Spore formers

29. 2 weeks post URI
Bladder ca risk factors
When does minimal change dz occur?
Transduction
3 toxins of bacillus

30. Adriamycin - Phen - Fen (Phentermine - fenfluramine)
Enzymes ONLY seen in glycolysis
Drugs that cause cardic fibrosis
Erythema marginatum
P450 Inducers

31. Smoking - Alcohol - Nitrates - Japanes
Esophageal/gastric ca risk factors
6 Low Complement Associated Nephrotic Syndromes
Sulfa containing drugs
IP3/DAG

32. Gram negative rods - Pleomorphic - 'School of fish' - Type A = non - encapsulated - non - invasive - MCC of sinusitis - otitis - bronchitis - Type B = encapsulated - invasive - IgA protease - MCC of epiglottitis
Hemophilus Influenza
Characteristics of Mitochondrial Inheritance
Cancer associated with Akanthosis nigricans
HER- II - Neu - Erb - BRCA-1 & II - p53 - CSF-1

33. G-6- PD
Pityriasis rosea
X- linked Dominant Inheritance diseases
Chinese letters
Heinz body

34. P41: just a surface marker - GP120: attachment to CD4 - p17 & p24 antigens: assembly - Pol: transcription - Reverse transcriptase: integration
n - myc
Drugs that trigger autoimmune thrombocytopenia
Job of chylomicrons
Parts of HIV viron

35. Beta1 selective: A ? M (except C&L) - Nonselective: N ? Z - C - L
Cause of Bullous Emphysema
Responsible for Bends
Beta- Blockers
MCC Pneumonia in Elderly

36. Red macules - target lesions - allergy and viruses - Mild - MCC is viral (2nd = drugs) - Moderate - Stevens Johnson Syndrome - Severe - Toxic Epidermal Necrolysis
Erythema multiforme
Amino acid subgroups: Smallest
AA Amyloidosis
Ca:Calmodulin

37. Cystic Fibrosis - Closed angle glaucoma
NO
Uses for Pilocarpine
Hormones produced by the placenta
Cancer associated with urticaria (hives)

38. Restriction enzyme that cuts to the right of Gly - Ser - Ala
Characteristics of Mitochondrial Inheritance
Job of LDL
Elastase
Autoimmune Antibodies found in Mixed Connective Tissue Dz

39. VSD - ASD - PDA - Coarctation of aorta
cGMP
Restriction enzymes
Newborn screening tests
MC Non - cyanotic congenital heart dz

40. Multiple Myeloma
Gram + Spore formers
Autoimmune Antibodies found in Multiple Sclerosis
Dermatitis herpetiformis
Russell body

41. A1- antitrypsin deficiency
P450 Inhibitors
Cause of Panacinar Emphysema
Cancer associated with urticaria (hives)
Electron Transport Chain Physical Uncouplers

42. Aspirin
Electron Transport Chain Physical Uncouplers
NO
Autoimmune Antibodies found in Multiple Sclerosis
Amino acid subgroups: Basic

43. Cys - Met
Heart block clue
If cell mediated is defective - tx for
Amino acid subgroups: Sulfur Bonds
X- linked enzymes deficiencies

44. Job - Buckley Syn - NADPH Oxidase dfic - Neutropenia - Myeloperoxidase defic
Compartment syndrome
1 dose tx for Gardenella
Neutrophil deficiencies
Auer Rods

45. 'Oh BED' - O antigen (Salmonella) - Botulinum - Erythrogenic toxin - Diptheria
Hormones produced by small cell ca of lung
Phage Mediated Toxins
Conditions that cause Reiter's Syndrome
6 Low Complement Associated Nephrotic Syndromes

46. Pyremethamine/sulfadiazine - Trimethroprim/Sulfamethoxaole - Methotrexate
Cancer associated with Dermatomyositis (heliotropic - malar)
Dihydrofolate Reductase Inhibitors
NO
AE Amyloidosis

47. Increased body temperatur with normal heart rait - HR should increase by 10 bpm for every 1 degree increase in temperature
Autoimmune Antibodies found in Celiac Sprue
NO
Electron Transport Chain Physical Uncouplers
Heart block clue

48. Deficiency in branched amino acids (Leu - Lys - Val) - Defective transport in the kidneys
Most frequent cause of UTI in females 5-10 yo & 18-24 yo
Maple Syrup Urine Disease (MSUD)
6 Low Complement Associated Nephrotic Syndromes
Autoimmune Antibodies found in Progressive Systemic Sclerosis

49. Metronidazole - Clindamycin - Cefoxitin

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50. Restriction enzyme that cuts to the right of Met - Cys
Hormones produced by the placenta
Mercaptoethanol
Rust Colored sputum
c - myb