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KJZ PP Clues

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Answer 50 questions in 15 minutes.
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1. 'I'D SMACK Quin' - INH - Dapsone - Sulfa drugs - Macrolides - Amiodarone - Cimetidine - Ketoconazole - Quinolones
P450 Inhibitors
Places where amino acids feed in/out of TCA cycle: Acetyl CoA
AVMs machinery murmur
Pick body

2. Cystic Fibrosis - Closed angle glaucoma
Uses for Pilocarpine
Autoimmune Antibodies found in Celiac Sprue
Rust Colored sputum
Fanconi Syndrome

3. Crohn's diesase
Disease picked up during delivery
Oxalate stones in adult male or female
AP amyloidosis
Nephrotic Syndrome

4. Membranous GN
Dermatitis herpetiformis
MC Nephrotic dz in adults
Autoimmune Antibodies found in Sjogren's
T- cytotoxic cells

5. Rheumatic fever
Cyanobromide
MCC Meningitis 0 - 2 months
Places where amino acids feed in/out of TCA cycle: Fumerate
Aschoff body

6. 'LSD Loves Company' - Lyme Dz - Salmonella - Diptheria - Legionalla - Chagas
MCC Pneumonia 40 yrs - 65 yrs
Bugs that cause heart block
Thrombolytics & rescues
Drug Induced SLE

7. Mantle Cell Lymphoma
5 causes of SIADH
Translocation 11:14
c - myb
MCC Meningitis > 21 yrs

8. Diabetes Hyperkalemia - NO aldosterone (infarcted JG apparatus)
Erythema chronicum migrans
Enzymes ONLY seen in glycolysis
Type IV
Erythema marginatum

9. 2nd Messenger - Smooth muscle contraction by horm/NT - All hypothatlmic hormones (except CRH)
Neutrophil deficiencies
Autoimmune Antibodies found in Myesthenia Gravis
IP3/DAG
MCC Meningitis > 21 yrs

10. Burkitt's Lymphoma
Bugs with IgA Protease ( = resistant to IgA)
1 dose tx of Trichomonas
Cancer Grade versus Stage
c - myc

11. Cys - Met
Characteristics of Autosomal Dominant Inheritance
Amino acid subgroups: Sulfur Bonds
HER- II - Neu - Erb - BRCA-1 & II - p53 - CSF-1
Transduction

12. Methylene blue
Methemaglobinemia chelators
MC Renal Dz in HIV/drug users
Causes of Papillary Necrosis
Elevated TGs

13. 1. E. coli (nitrate) 2. Proteus 3. Klebsiella
Pansystolic murmurs
MCC of UTI
AL Amyloidosis
Macrophages

14. P wave = Ca - QRS complex = Na - S- T inteval = Ca - T wave = K - U wave = Na
Electron Transport Chain Physical Uncouplers
Ions responsible for different parts of the EKG
Encapsulated yeast
Elevated cholesterol

15. Deficiency in branched amino acids (Leu - Lys - Val) - Defective transport in the kidneys
Maple Syrup Urine Disease (MSUD)
Pansystolic murmurs
Periods of rapid growth
S. aureus

16. Phosphorylase - Debranching enzyme - a -1 -6- glucosidase - Phosphatase
Cancer associated with Paget's Disease
Enzymes necessary to break down Glycogen
Globoid
Tinea cruris

17. A1- antitrypsin deficiency
Cause of Panacinar Emphysema
1 dose tx for Gonorrhea
Transformation
MCC of newborn meningitis

18. S. Pneumonia - Viruses - Anaerobes - H. influenza - Gram negative rods
Pulmonary Infiltrate w/ Eosinophilia
bcl -2
MCC Pneumonia in Elderly
Fanconi Syndrome

19. Multiple Myeloma
Erythema marginatum
Causes of low volume state with acidosis (not alkalosis)
Enzymes NEVER seen in glycolysis
Russell body

20. 'Some Strange Killers Have Pretty Nice Capsules' - Strep. pneumo (gr +) - Salmonella - Klebsiella - H. Flu B - Pseudomonas - Neisseria - Citrobacter
Encapsulated Bacteria
Structures with no known function
Positive stranded RNA
Massive Eosinophilia

21. Metronidazole - Clarithromycin - Zinc deficiency
B- cell deficiencies
Amino acid subgroups: Bulky (Aromatic)
Cause dysguzia
Erythema multiforme

22. AZT - Benzene - Chloramphenecol - Vinblastin
Risk factors for primary liver cancer
Primary Allergic Response
Drugs that blast BM
Trypsin

23. Restriction enzyme that cuts to the right of amino terminal
Councilman body
Pre - albumin/transthyretin Amyloidosis
Transduction
Aminopeptidase

24. Normal CD4 count: 800-1200 in adults - up to 1500 in kids - < 500 begin treating w/ 2 nucleotide inhibitors & 1 protease inhibitor (750 in kids) - <200 = AIDS - add tx for PCP - <100 add tx for MAC
Autoimmune Antibodies found in Sjogren's
Strep Pyogenes
CD4 counts to start treatment in HIV pt
Pseudogout

25. Mycoplasma - Nocardia (partially - gram +) - Cryptosporidium (partially - protozoa)
MC Nephrotic dz in kids
Acid fast organisms
Causes of Microstatosis
Viruses related to Ca

26. Niemann - Pick dz
4 D's of Pellagra
Zebra body
Autoimmune Antibodies found in Primary Biliary Cirrhosis
Electron Transport Chain Chemical Uncouplers

27. Herpes
Most frequent cause of UTI in females 5-10 yo & 18-24 yo
Dihydrofolate Reductase Inhibitors
Maximum sinus rate
Cowdry Type A body

28. Morbiliform rash - preceded by cough & conjunctivitis
Measles
Oxalate stones in adult male or female
Encapsulated Bacteria
Mitochondrial diseases

29. Strep Bovis - Bacteroides fragilis - C. melanogo - speticus - C. difficlile - If blood cx show S. bovis or C. melanogo - septicus = r/o colon ca

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30. Only occurs if bacteria has PILI
Conjugation
Pre - renal failure
c - myb
Translocation 17:22

31. Glu - Gln
Characteristics of Autosomal Recessive Inheritance
Crescent shaped Protozoa
Autoimmune Antibodies found in Multiple Sclerosis
Places where amino acids feed in/out of TCA cycle: a - ketoglutarate

32. Scabies - Lichen planus - Urticaria - Dermatitis herpetiformis
Amino acid subgroups: Branched
Itchies rashes
Functions of adhesion molecules
Transformation

33. Ca pyrophosphate - + birefringent crystals - rhomboid crystals - MC older pts - Seen equally in both genders - tx = colchicine
Neutrophil deficiencies
Tx for 'Big Mama' anaerobes
Pseudogout
6 Low Complement Associated Nephrotic Syndromes

34. B2 microglobin
AB Amyloidosis
When does minimal change dz occur?
Glutaminase
Carboxypeptidase

35. Small cell carcinoma of the lung
MCC Pneumonia 6 wks - 18 yrs
P450 Inhibitors
l - myc
Second messengers

36. Ovarian tumor
Call - Exner body
Amino acid subgroups: Glucogenic
Compartment syndrome
Ca:Calmodulin

37. Hilum - Pelvic Brim - Entrance of bladder
Encapsulated yeast
Cavities of blood loss
Thrombolytics & rescues
3 Anatomical Narrowings of Ureter

38. Job - Buckley Syn - NADPH Oxidase dfic - Neutropenia - Myeloperoxidase defic
Autoimmune Antibodies found in Myesthenia Gravis
Neutrophil deficiencies
Tinea cruris
Translocation 11:14

39. Statins: PALS - Provostatin (only renally excreted) - Atorvastatin - Lovastatin - Simvastatin (LFTs q 3 mos) MoA: Inhibit HMG CoA reductase - most active around 8 pm - must take at night for max efficacy
Tx for Hypercholesterolemia
CEA
Cancer associated with Dermatomyositis (heliotropic - malar)
IgA nephropathies

40. 'IHOP' - Intractable pain - Hemorrhage - Obstruction - Perforation
MCC Croup & Bronchiolitis
T&B cell deficiencies
l - myc
Indications for PUD surgery

41. Chlorpropamide - Lactams - Antabuse - Metronidazole
Enzymes necessary to break down Glycogen
Progressing to RPGN
P450 Inducers
Drugs that cause disulfram reaction

42. In collecting duct - Absorbs ammonia in the liver - Cause of hepato - renal syndrome
cGMP
Tx for Cyanide poisoning
Glutaminase
Pityriasis rosea

43. Colon ca - AML
P450 Inhibitors
c - myb
Job of LDL
Basal body

44. Wiskott - Aldrich Syndrome (WAS) - SCID - CVID - HIV (HTLV-1) - Job - Buckley Syndrome
Call - Exner body
T&B cell deficiencies
1 dose tx for Gonorrhea
Seborrheic dermatitis

45. Neurofibromatosis
Autoimmune Antibodies found in Hashimoto's
TB Treatments
Translocation 17:22
Salmonella typhi

46. Plasma (RTA) - Ammonia production in the collection duct - 10% of urea cycle - Glutaminase - Carbonic anhydrase
MC Malignant Renal tumor in adults
4 sources of renal acid
Strep Pyogenes
c - abl

47. Xanthelasmas on eyelids & face - Increased risk for pancreatitis
Elevated TGs
Autoimmune Antibodies found in Sjogren's
Actions of E. coli
Esophageal/gastric ca risk factors

48. Restriction enzyme that cuts to the left of carboxy terminal
Neutrophil deficiencies
Erythema marginatum
Carboxypeptidase
1 dose tx Vaginal Candidiasis

49. 'PIGI' - Prolactin - Inhibin - GH - Insulin
Disulfide bonds
Sulfa containing drugs
TH2 secrete
T- cell deficiencies

50. CML - All
Typohoid fever
c - abl
Cyanide chelator
Carcinoid triad

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KJZ PP Clues

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