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KJZ PP Clues

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Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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1. 1. Microglia 2. Type I pneumo 3. Kupffer 4. RES cells 5. Mesangial 6. Dendritic 7. Langerhans 8. Osteoclasts 9. Histiocytes - giant cells - epithelioid
1 dose tx Vaginal Candidiasis
Names of macrophages in specific tissue types: 1. Brain 2. Lung 3. Liver 4. Spleen 5. Kidney 6. LN 7. Skin 8. Bone 9. CT
Mitochondrial diseases
Hormones produced by small cell ca of lung

2. Edema - Hyperlipidemia - Hypercholesterolemia - Hypercoagulability - serum albumin - urine albumin
Tx for Cyanide poisoning
Nephrotic Syndrome
Schiller - Duvall
Enzymes necessary to break down Glycogen

3. Anti - Ribonuclear protein
AP amyloidosis
CEA
Autoimmune Antibodies found in Mixed Connective Tissue Dz
HER- II - Neu - Erb - BRCA-1 & II - p53 - CSF-1

4. PPUNCHeS - Proteus - Pseudomonas - Ureaplsma urealyticum - Nocardia - Cryptococcus neoformans - H. pylori - S. Saprofiticus
Progressing to RPGN
Hormones produced by the placenta
Urease positive bacteria
Oxaloacetate

5. All females will pass on the disease - No males will pass on the disease - All offspring of affected females will be affected - Often affects CNS - heart - and skeletal muscle - Due to uneven cytokinesis during meiosis/oogenesis
Characteristics of Mitochondrial Inheritance
NO
Strep Pyogenes
Elevated cholesterol

6. Diabetes Hyperkalemia - NO aldosterone (infarcted JG apparatus)
Cancer associated with Actinic keratosis
Amino acid subgroups: Gluco & Ketogenic
IP3/DAG
Type IV

7. Morbiliform rash - preceded by cough & conjunctivitis
Encapsulated Bacteria
Measles
Amino acid subgroups: Gluco & Ketogenic
Oxalate stones in adult male or female

8. Takes triglycerides from GI to liver & endothelium
Negri body
Job of chylomicrons
Course of Hep B
Newborn screening tests

9. Portion homologous with Ig Light chain - Primary amyloidosis - multiple myeloma
Autoimmune Antibodies found in Progressive Systemic Sclerosis
Macrophage deficiency
Indications for PUD surgery
AL Amyloidosis

10. Unique N- terminal sequence - Chronic active dz - Hodgkin's dz
Autoimmune Antibodies found in SLE
Elevated TGs
AA Amyloidosis
Acid fast organisms

11. Defect in proximal tubule - Can't reabsorb - Low energy state - Can be caused by old tetracycline
Gram + Spore formers
Cystic fibrosis
Fanconi Syndrome
Cowdry Type A body

12. Smoking - Aniline dyes - Benzene - Aflatoxin - Cyclophosphamie - Schistosomiasis - Von Hippel - Lindau - Tuberous sclerosis
CVID
Bladder ca risk factors
bcl -2
Mitochondrial diseases

13. HCG - Inhibin - Human placental lactogen - Oxytocin - Progesterone - Estrogen
Hormones produced by the placenta
5 causes of SIADH
9 live vaccines
NO

14. Anti - thyroglobulin - Anti - microsomal

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15. Colon cancer (HIV is sudden ?)
Cancer associated with Akanthosis nigricans
Autoimmune Antibodies found in Myesthenia Gravis
Massive Eosinophilia
Cancer associated with Seborrheic keratosis

16. Memory - IgG shows up at day 3 with 5x the concentration - Highest affinity for antigen - Peaks in 5 years - stays for 10 years
Hemophilus Influenza
Secondary Allergic response
Autoimmune Antibodies found in Sjogren's
Job - Buckley Syndrome

17. Deletion of chr 22 - Problem with 3rd & 4th pharyngeal pouches - Hypokalemia

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18. Burkitt's Lymphoma
Nephrotic Syndrome
Progressing to RPGN
c - myc
Esophageal/gastric ca risk factors

19. CD-8 + CD-4 - Recognize MHC I - Also have markers CD-2 & CD-3
Mitochondrial diseases
If cell mediated is defective - tx for
T- cytotoxic cells
1 dose tx Vaginal Candidiasis

20. Asp - Asn
Job - Buckley Syndrome
Translocation 11:22
Actions of E. coli
Oxaloacetate

21. Fresh Frozen Plasma (FFP)
Autoimmune Antibodies found in Scleroderma
MCC Pneumonia 18 yrs - 40 yrs
Rescue for active hemorhage
Autoimmune Antibodies found in Polyarteritis Nodosa

22. Whipple's disease
Tx for Cyanide poisoning
Autoimmune Antibodies found in Pemphigus Vulgaris
Job of chylomicrons
Oxalate stones in adult female

23. 'KIISS' - Kills T- cells & eosinophils - Inhibit macrophage migration - Inhibit phospholipase A - Inhibit mast cell degranulation - Stabilizes endothelium - Stimulates protein synthesis
Action of steroids
Autoimmune Antibodies found in T1DM
Heart block clue
Translocation 11:22

24. Red macules - papules - vesicles - pustles then scabs; different stages at teh same time - HHV 3
Wiscott - Aldrich Syndrome (WAS)
Typohoid fever
MC Malignant Renal tumor in adults
Varicella Zoster

25. 2nd Messenger - Gastrin
Amino acid subgroups: N- Bonds
Ca++
Painful Genital Lesions
Autoimmune Antibodies found in Goodpasture's

26. Single aa substitution - Hereditary neuropathy - nephropathy - & cardiopathy
MCC Pneumonia 6 wks - 18 yrs
Beta- Blockers
AB Amyloidosis
Pre - albumin/transthyretin Amyloidosis

27. Wiskott - Aldrich Syndrome (WAS) - SCID - CVID - HIV (HTLV-1) - Job - Buckley Syndrome
Erythema chronicum migrans
T&B cell deficiencies
HIV (HTLV-1)
Cancer associated with urticaria (hives)

28. MC infection of shunts & central lines
Drugs that cause cardic fibrosis
Zebra body
Drugs that cause disulfram reaction
Staph Epidermiditis

29. Beta1 selective: A ? M (except C&L) - Nonselective: N ? Z - C - L
Beta- Blockers
Course of Hep B
Bacteria associated with colon ca
Chinese letters

30. MC bacteria is Strep viridans - Roth spots (eyes) - Janeway lesions (toes) - Osler's nodes (fingers) - splinter hemorrhages - endocarditis - mycotic aneurysm (septic emboli)
Subacture Bacterial Endocarditis cause & sx
cGMP
Autoimmune Antibodies found in Goodpasture's
Enzymes necessary to break down Glycogen

31. Ovarian tumor
Call - Exner body
Auer Rods
Characteristics of Autosomal Dominant Inheritance
Amino acid subgroups: O- Bonds

32. Aspirin
Drug Induced SLE
Electron Transport Chain Physical Uncouplers
T- cytotoxic cells
Basal body

33. Anti - P- ANCA
Autoimmune Antibodies found in Polyarteritis Nodosa
Enzymes NEVER seen in glycolysis
Maple Syrup Urine Disease (MSUD)
Amino acid subgroups: Glucogenic

34. Combo of Type I & II - Normal urine pH - Hypokalemia
Bacteria w/ toxins that inhibit EF-2
Amino acid subgroups: Sulfur Bonds
Type III Renal Tubular Acidosis
Autoimmune Antibodies found in Progressive Systemic Sclerosis

35. Lethal factor - Protective factor - Edema factor
Amino acid subgroups: Smallest
X- linked Dominant Inheritance diseases
3 toxins of bacillus
T- cytotoxic cells

36. High urine pH - Acidosis - Frequent UTI - Stones - Babies die <1 yr
Trinucleotide repeats are found in these diseases
Enzymes NEVER seen in glycolysis
Causes of severe monocytosis
Type I Renal Tubular Acidosis

37. Statins: PALS - Provostatin (only renally excreted) - Atorvastatin - Lovastatin - Simvastatin (LFTs q 3 mos) MoA: Inhibit HMG CoA reductase - most active around 8 pm - must take at night for max efficacy
Auer Rods
Tx for Hypercholesterolemia
Lewy body
Autoimmune Antibodies found in T1DM

38. Linear excoriation on belt line & finger webs
Scabies
Causes of low volume state with acidosis (not alkalosis)
Most frequent cause of UTI in females 5-10 yo & 18-24 yo
Translocation 9:22

39. 'Oh BED' - O antigen (Salmonella) - Botulinum - Erythrogenic toxin - Diptheria
Phage Mediated Toxins
MC Nephrotic dz in adults
SCID
Hemolytic properties of Strep a - Beta - ?

40. Asp - Glu
Sweat test
Amino acid subgroups: Acidic
9 live vaccines
Strep Pyogenes

41. Pro
CEA
MCC Meningitis > 21 yrs
1 dose tx of Trichomonas
Places where amino acids feed in/out of TCA cycle: Fumerate

42. Multiple Myeloma
Russell body
MCC Pneumonia 6 wks - 18 yrs
1 dose tx for Gardenella
Nephrotic Syndrome

43. Anti - Acetylcholine receptor
Cystic fibrosis
Autoimmune Antibodies found in Myesthenia Gravis
P450 Inducers
Gram - that are strict Anaerobes

44. Incubation: 4-26 wks (8 wk average) Acute dz: 4-12 wks Convalescence: 4-20 wks Recovery: yrs
CEA
Course of Hep B
Bacteria w/ toxins that inhibit EF-2
Cause of Panacinar Emphysema

45. Retinoblastoma
Cancer associated with Akanthosis nigricans
Rb
MC Nephrotic dz in adults
Donovan body

46. Only lipoprotein to carry cholesterol - Breakdown product of VLDL
Indications for PUD surgery
TH2 secrete
CD4 counts to start treatment in HIV pt
Job of LDL

47. G-6- PD
Job of LDL
Heinz body
MC COD in HIV
Timing of Immune System Response

48. Celiac Sprue
Parts of HIV viron
MCC of airway infection
Carboxypeptidase
Oxalate stones in 5 yo black female

49. Pick's disease
CEA
Amino acid subgroups: Bulky (Aromatic)
Conditions that cause Reiter's Syndrome
Pick body

50. 2nd Messenger - Smooth muscle contraction by horm/NT - All hypothatlmic hormones (except CRH)
Places where amino acids feed in/out of TCA cycle: Acetyl CoA
IP3/DAG
Comma Shaped Bugs
S. aureus