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KJZ PP Clues

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. 1st Contact - Neutrophils work first 3 days - Then B- cells make IgM - peaks at 14 days - gone in 2 mos - IgG shows up at 2 weeks - peaks in 2 mos - gone in 1 yr
Dermatomyositis
Primary Allergic Response
MCC Pneumonia 18 yrs - 40 yrs
Tx for Cyanide poisoning

2. IL-2 - IF- gamma
Drugs that cause pulmonary fibrosis
1 dose tx of Trichomonas
Mercaptoethanol
TH1 secrete

3. Leigh's dz: subacute necrotizing encephalomyelopathy - progressive ?IQ - seizures - ataxia - cytochrome oxidase deficiency - Leber's dz: hereditary optic atrophy
Mitochondrial diseases
Rashes of palm & soles
Causes of low volume state with acidosis (not alkalosis)
Places where amino acids feed in/out of TCA cycle: Pyruvate

4. Hypomagnesia - Hypocalcemia (except atrium) - Hyperkalemia - Hyponatremia
c - abl
Councilman body
SCID
More likely to depolarize

5. 'NAACP' - Neoplasms - Allergies/asthma - Addison's - Collagen Vascular dz - Parasites
If cell mediated is defective - tx for
AL Amyloidosis
c - myc
Massive Eosinophilia

6. ACTH (MC) - ADH - PTH - TSH - ANP
Cause of Centroacinar Emphysema
3 toxins of bacillus
Hormones produced by small cell ca of lung
Russell body

7. IL-4 - IL-5 - IL-6 - IL-10
TH2 secrete
Lead chelator
Causes of Microstatosis
Causes of Papillary Necrosis

8. Granulomatous (nonbacterial)
Causes of severe monocytosis
Action of steroids
Macrolides
Cancer associated with Erythema nodosum

9. Complex I - Amytal - Rotenone - Complex II - Malonate - Complex III - Antimycin - Complex IV - CN - CO - Chloramphenicol - Complex V - Oligomycin
Electron Transport Chain Poisons
Amino acid subgroups: Bulky (Aromatic)
S-100
Methotrexate uses

10. Dx: Fragile X - Tx: Molar Pregnancy - Fast Growing Ca - Steroid resistant disease
Methotrexate uses
MC Renal Dz in HIV/drug users
Odd MCC of Death
Cancer associated with urticaria (hives)

11. Niemann - Pick dz
Less likely to depolarize
Crohn's d
Psammoma bodies
Zebra body

12. Histaminase - Arylsulfatase - Heparin
MI enzymes
Positive stranded RNA
Secretions of eosinophil
Enzymes ONLY seen in glycolysis

13. Anti - Glomerular Basement Membrane (AKA Type IV Collagen)

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14. Smoking - Aniline dyes - Benzene - Aflatoxin - Cyclophosphamie - Schistosomiasis - Von Hippel - Lindau - Tuberous sclerosis
Course of Hep B
Bladder ca risk factors
Hormones produced by the placenta
Risk factors for primary liver cancer

15. Sulfonamides - Sulfonlureas - Celecoxib (COX 2 inhibitor)
Blood gas w/ obstructive lung dz
Sulfa containing drugs
1 dose tx Vaginal Candidiasis
Cystic fibrosis

16. Pro
Places where amino acids feed in/out of TCA cycle: Fumerate
CEA
B Vitamins
Ca:Calmodulin

17. Anti - thyroglobulin - Anti - microsomal

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18. Strep Pneumoniae (AKA pneuococcus)
Trypsin
Amino acid subgroups: Branched
Rust Colored sputum
Varicella Zoster

19. Anti - Topoisomerase
B- cell deficiencies
Phage Mediated Toxins
Chinese letters
Autoimmune Antibodies found in Progressive Systemic Sclerosis

20. 2nd Messenger - Smooth muscle contraction by horm/NT - All hypothatlmic hormones (except CRH)
IP3/DAG
Course of Hep B
Enzymes used by B12
Periods of rapid growth

21. Beta1 selective: A ? M (except C&L) - Nonselective: N ? Z - C - L
Nephritis Syndrome
Beta- Blockers
1 dose tx of Trichomonas
Diptheria

22. Troponin I: appears 2 hrs - peaks 2 days - gone 7 days - CKMB: appears 6 hrs - peaks 12 hrs - gone 2 days - LDH: appears 1 day - peaks 2 days - gone 3 days
MI enzymes
Low Complement Bugs
Aminopeptidase
Crescent shaped Protozoa

23. Effects CD-4 rich tissues (brain - testicles - cervix - rectum - blood vessels) - T>B
Aschoff body
Low Complement Bugs
Places where amino acids feed in/out of TCA cycle: a - ketoglutarate
HIV (HTLV-1)

24. Memory - IgG shows up at day 3 with 5x the concentration - Highest affinity for antigen - Peaks in 5 years - stays for 10 years
Amino acid subgroups: Bulky (Aromatic)
TH2 secrete
Secondary Allergic response
Aschoff body

25. TH1 - TH2
Methemaglobinemia chelators
Secretions of eosinophil
Russell body
TH0 secrete

26. Red headed female - Tyrosine kinase deficiency
Job - Buckley Syndrome
Phage Mediated Toxins
Beta- Blockers
Erythema multiforme

27. Pyremethamine/sulfadiazine - Trimethroprim/Sulfamethoxaole - Methotrexate
Autoimmune Antibodies found in Wegener's
Translocation 8:14
Dihydrofolate Reductase Inhibitors
Subacture Bacterial Endocarditis cause & sx

28. Combo of Type I & II - Normal urine pH - Hypokalemia
Howell - Jolly body
Pulmonary Infiltrate w/ Eosinophilia
Type III Renal Tubular Acidosis
Conjugation

29. Cystathione synthase deficiency - Cysteine - ornithine - lysine - and arginine end up in urine - stones
Cystinuria
Bladder ca risk factors
X- linked enzymes deficiencies
Characteristics of Autosomal Recessive Inheritance

30. Phe - Iso - Thr - Tyr - Lys - Leu
Places where amino acids feed in/out of TCA cycle: Acetyl CoA
AB Amyloidosis
Negri body
Co - factors for Pyruvate DH - a - ketogluterate DH - & Branched Chain DH

31. Anti - epidermal basement membrane protein
1 dose tx for H. ducreyi
Tx for 'Big Mama' anaerobes
MCC of airway infection
Autoimmune Antibodies found in Bullous pemphigoid

32. Sickle Cell
Renal Failure
Increased susceptibility to Pseudomonas & S. aureus
Howell - Jolly body
1 dose tx of Trichomonas

33. Anti - Platelet - (AKA glycoprotein IIb/IIIa)
Elastase
Translocation 11:14
Beta- Blockers
Autoimmune Antibodies found in Idiopathic Thrombocytic Purpura

34. Tyrosine kinase deficiency - Late onset - Frameshift/missense mutation
Places where amino acids feed in/out of TCA cycle: Fumerate
Lead chelator
CVID
Carboxypeptidase

35. Ca pyrophosphate - + birefringent crystals - rhomboid crystals - MC older pts - Seen equally in both genders - tx = colchicine
Less likely to depolarize
Pseudogout
Job of chylomicrons
Cavities of blood loss

36. MCC of osteomyelitis - MCC of infection in burn pts
Zebra body
S. aureus
Renal Failure
AA Amyloidosis

37. 2nd Messenger - Smooth muscle contration by distention
Ca:Calmodulin
Amino acid subgroups: Basic
Autoimmune Antibodies found in Hashimoto's
Pansystolic murmurs

38. CD-8 -CD-4 + - Recognize MHC II - Also have marker CD-2 & CD-3
Course of Hep B
T- Helper cells
Odd MCC of Death
Amino acid subgroups: Acidic

39. MC infection of shunts & central lines
Oxalate stones in 3 yo white female
Staph Epidermiditis
Amino acid subgroups: Smallest
Coumadin vs Heparin

40. Ceftriaxone - Cefixime - Cefoxitin - Ciprofloxacin - Ofloxacin - Gatifloxicin
Transduction
1 dose tx for Gonorrhea
Phases of Atrial Action Potential
Jones Criteria (J<3NES)

41. Anti - Epidermal anchoring protein receptor - AKA Intercellular junctions of epidermal cells
Autoimmune Antibodies found in Pemphigus Vulgaris
c - myc
Aminopeptidase
Silver staining bugs

42. Normal CD4 count: 800-1200 in adults - up to 1500 in kids - < 500 begin treating w/ 2 nucleotide inhibitors & 1 protease inhibitor (750 in kids) - <200 = AIDS - add tx for PCP - <100 add tx for MAC
5 causes of SIADH
Most frequent cause of UTI in females 5-10 yo & 18-24 yo
More likely to depolarize
CD4 counts to start treatment in HIV pt

43. 'GIFTS' - Granuloma - Ileum - Fistula - Transmural - Skip lesions

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44. His - Arg - Glu - Asp - Gln - Asn - Tyr - Cys - Pro - Met - Val - Ala - Gly
Amino acid subgroups: Glucogenic
Segmented Viruses
Oxaloacetate
Autoimmune Antibodies found in SLE

45. HIPPPE - Hydralazine - INH - Procainamide - Penicillamine - Phenytoin - Ethosuximide
Dermatomyositis
Translocation 8:14
Wiscott - Aldrich Syndrome (WAS)
Drug Induced SLE

46. Hexokinase - Phosphofructokinase -1 - Pyruvate kinase
Amino acid subgroups: Gluco & Ketogenic
Enzymes ONLY seen in glycolysis
1 dose tx for H. ducreyi
MCC Meningitis 10 - 21 yrs

47. Increased body temperatur with normal heart rait - HR should increase by 10 bpm for every 1 degree increase in temperature
Primary Allergic Response
Pre - renal failure
AE Amyloidosis
Heart block clue

48. Parainfluenza - RSV (ER this is #1) - Adenovirus - Influenza
Amino acid subgroups: Branched
MCC Croup & Bronchiolitis
Translocation 8:14
Crohn's d

49. Bruton's Agammaglobulinemia (Tyrosine kinase deficiency) - Leukemias - Lymphomas
Autoimmune Antibodies found in Myesthenia Gravis
B- cell deficiencies
Autoimmune Antibodies found in Sjogren's
Bugs with IgA Protease ( = resistant to IgA)

50. Alcohol
Translocation 8:14
Causes of Macrostatosis
l - myc
Disulfide bonds