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KJZ PP Clues

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Takes triglycerides from liver to adipose - Only made in the liver - Breaks down into IDL + LDL
Job of VLDL
MCC Meningitis 2 mo - 10 yrs
Chymotrypsin
Autoimmune Antibodies found in SLE

2. Normal CD4 count: 800-1200 in adults - up to 1500 in kids - < 500 begin treating w/ 2 nucleotide inhibitors & 1 protease inhibitor (750 in kids) - <200 = AIDS - add tx for PCP - <100 add tx for MAC
Places where amino acids feed in/out of TCA cycle: a - ketoglutarate
CD4 counts to start treatment in HIV pt
1 dose tx for Gonorrhea
MCC Meningitis 2 mo - 10 yrs

3. Focal Segmental GN
MC Renal dz in Blacks/Hispanics
MC Renal Dz in HIV/drug users
T- cytotoxic cells
Wiscott - Aldrich Syndrome (WAS)

4. Decreased: K - Na - Cl - increased: pH - BP
Uses for Pilocarpine
Drugs that trigger autoimmune hemolytic anemia
n - myc
Serum Values for Low Volume State

5. Takes triglycerides from GI to liver & endothelium
Oddities about listeria
Parts of HIV viron
MCC of newborn meningitis
Job of chylomicrons

6. Affects males & females equally - Manifests in heterozygous state - Can be transmitted by either parent - Often delayed onset (adult dx) - Vertical transmission - New mutations occur in germ cells of older fathers - Can exhibit reduced penetrance & v
Job of VLDL
Characteristics of Autosomal Dominant Inheritance
Drugs that blast BM
Rb

7. Anti - Mitochondria
Crescent shaped Protozoa
Cancer associated with Paget's Disease
Autoimmune Antibodies found in Primary Biliary Cirrhosis
1 dose tx for H. ducreyi

8. Pavementing - Margination - Diapedesis - Migration
c - sis
Extravasation
Ca++
Actions of E. coli

9. Anti - Melanocyte
Carboxypeptidase
MCC Meningitis 10 - 21 yrs
Autoimmune Antibodies found in Vitiligo
TH0 secrete

10. Phosphorylase - Debranching enzyme - a -1 -6- glucosidase - Phosphatase
AVMs machinery murmur
Hormones produced by small cell ca of lung
Enzymes necessary to break down Glycogen
Macrophages

11. Hexokinase - Phosphofructokinase -1 - Pyruvate kinase
Heart block clue
MCC Croup & Bronchiolitis
Methemaglobinemia chelators
Enzymes ONLY seen in glycolysis

12. <20 = normal - 30-60 = heterozygous for CF - > 60 definitive positive
Autoimmune Antibodies found in Idiopathic Thrombocytic Purpura
Positive stranded RNA
Sweat test
MI enzymes

13. Only occurs if bacteria has PILI
Conjugation
Progressing to RPGN
Cancer associated with Dermatomyositis (heliotropic - malar)
Autoimmune Antibodies found in CREST

14. Disease does not effect parents - Disease may be seen in siblings & uncles - Often early onset (early dx) - Disease only present when both alleles are mutant - Horizontal transmission - Usu enzyme defects (Inborn errors of metabolism)
4 D's of Pellagra
Characteristics of Autosomal Recessive Inheritance
Causes of low volume state with acidosis (not alkalosis)
Neural Crest Makes?

15. Pancreatitis (EtOH) - Kidney stones (bloody urine) - AAA (ripping - tearing pain) - Ischemic Bowel (bloody diarrhea)
Restriction enzymes
4 causes of severe abdominal pain
Bugs that cause heart block
Thrombolytics & rescues

16. Viridans (green pigment - SBE) - Mutans (cavities) - Sanguis - Salivaris - Bovis
MCC Pneumonia 18 yrs - 40 yrs
Oxalate stones in 5 yo black female
Odd MCC of Death
Group D Streptococcus

17. Tachypnea - decreased PCO2 - pO2 - increased pH
Pick body
Blood gas w/ restrictive lung dz
Less likely to depolarize
X- linked Dominant Inheritance diseases

18. Diflucan - 1 pill
Erythema marginatum
Cancer associated with Paget's Disease
1 dose tx Vaginal Candidiasis
Chymotrypsin

19. Normal aging
Cause of Distalacinar Emphysema
Methemaglobinemia chelators
Pulmonary Infiltrate w/ Eosinophilia
c - myc

20. Mitral regurg - Tricuspid regurg - VSD
Pansystolic murmurs
Trinucleotide repeats are found in these diseases
MI enzymes
Ca:Calmodulin

21. Small cell carcinoma of the lung
Varicella Zoster
l - myc
Risk factors for primary liver cancer
Amino acid subgroups: Sulfur Bonds

22. 'SIADH' - Small cell ca - Increased Intracranial Pressure - A Pain - Drugs - Hypoxia
Nephrotic Syndrome
5 causes of SIADH
Negri body
How do you tell catalas positive Staphylococci apart?

23. Ceftriaxone - Cefixime - Cefoxitin - Ciprofloxacin - Ofloxacin - Gatifloxicin
Amino acid subgroups: Glucogenic
1 dose tx for Gonorrhea
Causes of Microstatosis
Cyanotic heart diseases

24. Restriction enzyme that cuts to the right of amino terminal
Blood gas w/ obstructive lung dz
Aminopeptidase
SE of Statins
Causes of Macrostatosis

25. Azithromycin - Clarithromycin - Erythromycin
Progressing to RPGN
Macrolides
l - myc
Measles

26. Adriamycin - Phen - Fen (Phentermine - fenfluramine)
Autoimmune Antibodies found in Primary Biliary Cirrhosis
Pick body
Drugs that cause cardic fibrosis
ret

27. Unique N- terminal sequence - Chronic active dz - Hodgkin's dz
AA Amyloidosis
Sulfa containing drugs
Barr Body
Bugs that cause heart block

28. Anti - Myelin Receptors
Autoimmune Antibodies found in Multiple Sclerosis
l - myc
Carboxypeptidase
X- linked Dominant Inheritance diseases

29. Target lesion - bullseye - Lyme dz
Amino acid subgroups: Basic
Sulfa containing drugs
Oxalate stones in adult male or female
Erythema chronicum migrans

30. Goodpasture's (#1) - Diabetes Mellitis - HTN - Wagner's
Progressing to RPGN
Roseola
Pityriasis rosea
Names of macrophages in specific tissue types: 1. Brain 2. Lung 3. Liver 4. Spleen 5. Kidney 6. LN 7. Skin 8. Bone 9. CT

31. Lys - Leu
Elevated TGs
Maximum sinus rate
Amino acid subgroups: Ketogenic
Autoimmune Antibodies found in Polyarteritis Nodosa

32. Secrete vitamin K - Secrete biotin - Secrete folate - Secrete pantothenic acid - aids in absorption of B12
MC Renal Mass
Names of macrophages in specific tissue types: 1. Brain 2. Lung 3. Liver 4. Spleen 5. Kidney 6. LN 7. Skin 8. Bone 9. CT
Actions of E. coli
Neutrophil deficiencies

33. Burkitt's Lymphoma - c - myc activation
Autoimmune Antibodies found in Primary Biliary Cirrhosis
Cavities of blood loss
Translocation 8:14
Causes of Microstatosis

34. Methyl malonyl CoA mutase - Homocysteine methyl transferase
6 Low Complement Associated Nephrotic Syndromes
Amino acid subgroups: Basic
Serum Values for Low Volume State
Enzymes used by B12

35. Dx: Fragile X - Tx: Molar Pregnancy - Fast Growing Ca - Steroid resistant disease
Globoid
Methotrexate uses
ret
Transduction

36. Acidophilic: GH - Prolactin - Basophilic: TSH - ACTH - LH - FSH
Neutrophil deficiencies
Type I Renal Tubular Acidosis
Causes of Microstatosis
Anterior pituitary hormones

37. Group B strep - S. pneumonia - Herpes - N. gonorrhea - Chlamydia
Extravasation
Transduction
Translocation 15:17
Disease picked up during delivery

38. Burn pts - Cystic fibrosis - Diabetes - Neutropenics
Amino acid subgroups: N- Bonds
Increased susceptibility to Pseudomonas & S. aureus
Rust Colored sputum
Job - Buckley Syndrome

39. Reddened area w/ raised borders - does not blanch
4 D's of Pellagra
Enzymes necessary to make Glycogen
Erysipelas
MCC Pneumonia 40 yrs - 65 yrs

40. Release MHC II
Macrophages
Negri body
Course of Hep B
Disulfide bonds

41. ASA - Heparin - Quinidine
Autoimmune Antibodies found in Multiple Sclerosis
Odd MCC of Death
Drugs that trigger autoimmune thrombocytopenia
Indications for PUD surgery

42. Gene = on chr 7 - 2nd messenger is IP3/DAG - PIlocarpine can be used to treat (??)
Responsible for Bends
Translocation 14:18
Increased susceptibility to Pseudomonas & S. aureus
Cystic fibrosis

43. IL-2 - IF- gamma
4 D's of Pellagra
Translocation 15:17
TH1 secrete
Autoimmune Antibodies found in Graves

44. 2nd Messenger - Smooth muscle contraction by horm/NT - All hypothatlmic hormones (except CRH)
Dermatitis herpetiformis
Autoimmune Antibodies found in Polyarteritis Nodosa
IP3/DAG
Oddities about listeria

45. By pigment - Aureus = gold - Epidermidis = white - Saprophyticus = none
Rb
MC COD in HIV
P450 Inducers
How do you tell catalas positive Staphylococci apart?

46. S. aureus - Pseudomonas
Periods of rapid growth
Gastroenteritis within 8 hours of eating
Bacteria w/ Elastase
MCC Pneumonia 40 yrs - 65 yrs

47. 2 weeks post URI
4 D's of Pellagra
When does minimal change dz occur?
Carboxypeptidase
Erythema nodosum

48. I sprayed ORTHO on a BUNYA at the AreNA down in REO to kill SEGMENTED worms' - Orthovirdiae - Bunyavirdiae - Arenavirdiae - Reovirdiae
Seen in Rapidly Progressive GN (RPGN)
Segmented Viruses
Autoimmune Antibodies found in Mixed Connective Tissue Dz
Encapsulated yeast

49. Phe - Iso - Thr - Tyr - Lys - Leu
Translocation 9:22
Places where amino acids feed in/out of TCA cycle: Acetyl CoA
Type I Renal Tubular Acidosis
MCC Meningitis 2 mo - 10 yrs

50. TPA ? aminocaproic acid - Streptokinase ? aminocaproic acid - Warfarin ? Vitamin K - Heparin ? Protamine Sulfate
Thrombolytics & rescues
Drugs that blast BM
Timing of Immune System Response
Basal body