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Microbiology 2

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Cholangiocarcinoma
Clonorchis sinensis
Taenid solium
Mycobacterium avium - intracellulare
Aminoglycoside plus extended spectrum penicillin (piperacillin - ticarcillin)

2. Orthomyxoviruses
Nonenveloped - SS + - Icosahedral
Strongyloides stercoralis
Lysogeny
Enveloped - SS - - linear - 8 segments - Helical

3. Kala - azar: spiking fevers - hepatosplenomegaly - pancytopenia
Leishmania donovani
CMV
Mycobacterium avium - intracellulare
Wuchereria bancrofti

4. Botulinum exotoxin: Plasmid - lysogeny - bacterial chromosome?
Amphotericin B
Clostridium difficile - gas gangrene - double zone of hemolysis on blood agar
Lysogeny
Mycobacterium avium - intracellulare

5. Exotoxin A
Erythromycin
Pseudomonas - inactivates EF-2
Colonic epithelial cell necrosis and stimulation of fibrin deposition
Toxoplasma gondii

6. Treatment for systemic infection by systemic mycoses
Cryptococcus neoformans
Babesia
Amphotericin B
S. aureus. Binds Fc region of Ig. Prevents opsonization and phagocytosis.

7. Female mosquito; causes blockage of lymphatic vessels (elephantitis). Takes 9 months to 1 year after bite to get elephantiasis sx.
Wuchereria bancrofti
Picornavirus
Doxycycline - ceftriaxone
Praziquantel

8. Treatment for superficial candida infection
Mucor or Rhizopus spp.
Amphotericin B
Nystatin
HPV

9. Cycles occuring every other day; dormant form in liver -> tx w/primaquine
Bunyavirus
P. vivax/ovale
Mucor or Rhizopus spp.
Retrovirus

10. Protozoa: Rapidly fatal meningoencephalitis
Yellow fever
Topical miconazole - selenium sulfide
Enveloped - SS + - Icosahedral
Naegleria fowleri

11. Flavivirus
Quinine - clindamycin
Cryptosporidium
Enveloped - SS+ - linear - icosahedral
Clostridium difficile - gas gangrene - double zone of hemolysis on blood agar

12. Parasite: Hematuria - bladder CA
Diethylcarbamazine
Schistosoma haematobium
Dracunculus medinensis
Mucor or Rhizopus spp.

13. Fungal infection with rhinocerebral - frontal lobe abscesses
P. vivax/ovale
Mucor or Rhizopus spp.
Ascaris lumbricoides
Bunyavirus - hemorrhagic fever - pneumonia

14. Food contaminated with eggs; intestinal infection; causes anal pruritis
Enveloped - SS - - circular - 3 segments - helical
Enterobius vermicularis
Calicivirus
Reovirus

15. River blindness
Loa Loa
Rubeola
Onchocerca volvulus
Yellow fever

16. Tx of Paragonimus westermani
Praziquantel
Picornavirus
Trichomonas vaginalis
Clonorchis sinensis

17. Echovirus
Bacterial chromosome
Praziquantel
Metronidazole
Most common cause of aseptic meningitis

18. Picornaviruses
S. pneumoniae sensitive - S. viridans resistant
Nonenveloped - SS + - Icosahedral
Lysogeny
Rubella

19. Paramyxoviruses
Enveloped - SS - - linear - nonsegmented - Helical
Leishmania donovani
Enterobius vermicularis
Lysogeny

20. Lassa fever encephalitis
HHV-8
Clonorchis sinensis
Picornavirus
Arenavirus - spread by mice

21. Parainfluenza - croup
Paramyxovirus
Ascaris lumbricoides
Rubeola
Bartonella henselae (bacillary angiomatosis)

22. Tx for Babesia
Quinine - clindamycin
Toxoplasma gondii
Filovirus
CMV

23. Cercariae penetrate skin of humans; causes granulomas - fibrosis - and inflammation of the spleen and liver. Chronic infection can lead to squamous cell carcinoma of the bladder.
Diethylcarbamazine
Schistosoma
Amphotericin B
Dracunculus medinensis

24. Erythrogenic exotoxin of strep pyogenes: Plasmid - lysogeny - bacterial chromosome?
Lysogeny
Cleaves host cell rRNA (inactivates 60S ribosome); enhances cytokine release - causing HUS.
Trichinella spiralis
CMV

25. Cellulitis from animal bite
Pasteurella multocida
No envelope - SS + linear - Icosahedral
Enveloped - SS - - linear - Helical
Amphotericin B

26. Parasite: Liver cysts
Diethylcarbamazine
Enveloped - SS - - linear - 8 segments - Helical
Entamoeba histolytica
Echinococcus granulosus

27. Eggs in dog feces when ingested can cause cysts in liver; causes anaphylaxis if Ags are released from cysts (surgeons inject ethanol before removal to neutralize Ags).
Enterobius vermicularis
Rubella
Echinococcus granulosus
Nifurtimox

28. IgA protease
Enveloped - SS - - linear - 8 segments - Helical
Cleaves IgA. S. pneumoniae - H. influenzae type B - Neisseria (SHiN) in order to colonize respiratory mucosa.
Praziquantel
Retrovirus

29. Ingestion of larvae encysted in undercooked pork. Cysticercosis and neurocysticercosis - mass lesions in brain.
Cryptococcus neoformans
Icosohedral (double)
Rubella
Taenid solium

30. Cytotoxin B
Rubeola
Paramyxovirus
Cleaves host cell rRNA (inactivates 60S ribosome); enhances cytokine release - causing HUS.
Colonic epithelial cell necrosis and stimulation of fibrin deposition

31. Western equine encephalitis
Arenavirus
Lysogeny
Togavirus
Itraconazole or potassium iodide

32. Tx for Pseudomonas aeruginosa
No envelope - SS + linear - Icosahedral
Toxoplasma gondii
Aminoglycoside plus extended spectrum penicillin (piperacillin - ticarcillin)
Lysogeny

33. Rhinovirus
P. falciparum
Aminoglycoside plus extended spectrum penicillin (piperacillin - ticarcillin)
Clonorchis sinensis
Picornavirus

34. Tx for Toxocara canis
Echinococcus granulosus
Rubeola
Enveloped - SS + - Icosahedral
Diethylcarbamazine

35. Reovirus
Group A streptococcus. Helps prevent phagocytosis.
Onchocerca volvulus
No envelope
Pseudomonas - inactivates EF-2

36. Rickettsia transmitted by aerosol; no rash - no vector - neg Weil - Felix
Cryptococcus neoformans
Coxackie A - syphilis - Rocky Mountain spotted fever
Nifurtimox
Coxiella burnetti

37. Cytotoxin B
Lysogeny
Bunyavirus
C. Difficile
No envelope - SS + linear - Icosahedral

38. Pinworm
Arenavirus
Schistosoma haematobium
Nifurtimox
Enterobius vermicularis

39. Maltese cross in RBC
Babesia
Nonenveloped - SS + - Icosahedral
Icosohedral (double)
Toxocara canis

40. Tx for neurocystercercosis
Flavivirus
Dracunculus medinensis
bendazoles
Diphyllobothrium latum

41. Dilated cardiomyopathy - megacolon - megaesophagus
Trypansoma cruzi. Chagas dz - S. America
Congenital rubella
Watery diarrhea
Rubella

42. Reovirus
Sodium stibogluconate
Ribavirin
Strongyloides stercoralis
DS linear 10-12 segments

43. Shiga toxin: Plasmid - lysogeny - bacterial chromosome?
C. Difficile
Clonorchis sinensis
Bacterial chromosome
Babesia

44. Generalized lymphadenopathy particularly postauricular and occipital
Trichinella spiralis
Rubella
Mucor or Rhizopus spp.
S. aureus. Binds Fc region of Ig. Prevents opsonization and phagocytosis.

45. HTLV
Retrovirus
Invasive aspergillosis
Picornavirus
EBV

46. HIV - Encephalopathy
Doxycycline - ceftriaxone
JC virus (PML) results in demyelination
Mucor or Rhizopus spp.
Echinococcus granulosus

47. California encephalitis
Palivizumab
Lysogeny
Amphotericin B
Bunyavirus

48. HIV - Interstitial pneumonia; biopsy reveals cells with intranuclear and cytoplasmic inclusion bodies
Heart block - bilateral Bell's palsy
CMV
Arenavirus
Stains cryptococcus neoformans red

49. Ocular problems (cataracts - retinopathy - micropthalmos - glaucoma) - cardiovascular problems (PDA - VSD - pulmonary stenosis) - deafness - thrombocytopenia purpura - hepatosplenomegaly - CNS problems - bony lesions
Retrovirus
Rubeola
Rubella
Congenital rubella

50. Crimean - Congo hemorrhagic fever
Reovirus
Bunyavirus
Onchocerca volvulus
Enveloped - SS - - linear - nonsegmented - Helical