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Microbiology 2

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Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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1. Cytotoxin B
Heart block - bilateral Bell's palsy
EBV
Rubeola
C. Difficile

2. Cellulitis from animal bite
HHV-8
No envelope
Doxycycline - ceftriaxone
Pasteurella multocida

3. Parasite: Hematuria - bladder CA
Taenid solium
Schistosoma haematobium
Loa Loa
Coxackie A - syphilis - Rocky Mountain spotted fever

4. Optochin
Trichinella spiralis
Bunyavirus
CMV
S. pneumoniae sensitive - S. viridans resistant

5. HIV - Encephalopathy
JC virus (PML) results in demyelination
Trichinella spiralis
Enveloped - SS - - circular - helical
Flavivirus

6. Colorado tick fever
Clonorchis sinensis
Reovirus
Fluconazole or ketoconazole
C. Difficile

7. Protozoa: Bloating - flatulence - foul - smelling - fatty diarrhea
Yellow fever
Enterobius vermicularis
Clonorchis sinensis
Giardia lamblia

8. Ingestion of larvae encysted in undercooked pork. Cysticercosis and neurocysticercosis - mass lesions in brain.
Taenid solium
Congenital rubella
Wuchereria bancrofti
No envelope - SS + linear - Icosahedral

9. Echovirus
Bunyavirus
Watery diarrhea
Praziquantel
Picornavirus

10. Western equine encephalitis
Group A beta - hemolytic strep (S. pyogenes) sensitive. Group B (S. agalactiae) resistant.
Bacterial chromosome
Togavirus
Trichinella spiralis

11. Rash preceded by cough - coryza - conjunctivitis
Colonic epithelial cell necrosis and stimulation of fibrin deposition
Naegleria fowleri
Praziquantel
Rubeola

12. Exotoxin A
Clonorchis sinensis
Pseudomonas - inactivates EF-2
Rubella
Schistosoma haematobium

13. Rhabdoviruses
DS linear 10-12 segments
Orthomyxovirus
Arenavirus - spread by mice
Enveloped - SS - - linear - Helical

14. Shiga toxin
Schistosoma haematobium
Coxackie A - syphilis - Rocky Mountain spotted fever
No envelope - SS + linear - Icosahedral
Cleaves host cell rRNA (inactivates 60S ribosome); enhances cytokine release - causing HUS.

15. Undercooked meat (pork)
Schistosoma haematobium
Trichinella spiralis
Strongyloides stercoralis
Group A beta - hemolytic strep (S. pyogenes) sensitive. Group B (S. agalactiae) resistant.

16. Prophylaxis in close contacts of pts w/Haemophilus influenzae meningitis
Giardia lamblia
Rifampin
Wuchereria bancrofti
S. pneumoniae sensitive - S. viridans resistant

17. Diphtheria toxin: Plasmid - lysogeny - bacterial chromosome?
Mycoplasma pneumonia
Lysogeny
Rubella
Orthomyxovirus

18. Councilman bodies (acidophilic inclusions) in liver
Itraconazole or potassium iodide
Yellow fever
Reovirus
Enveloped - SS - - linear - Helical

19. 'Soap bubble' lesion in brain
No envelope
Cryptococcus neoformans
Pneumocystis jiroveci
Mucor or Rhizopus spp.

20. Orthomyxoviruses
Ivermectin
Enveloped - SS - - linear - 8 segments - Helical
No envelope - SS + linear - Icosahedral
Cryptococcus neoformans

21. Triad of chorioretinitis - hydrocephalus - intracranial calcifications
Enveloped - SS - - linear - 8 segments - Helical
Icosohedral (double)
Congenital Toxoplasma gondii
Flavivirus

22. HTLV
Reovirus
Retrovirus
Flavivirus
Toxoplasma gondii

23. Food contaminated with eggs; intestinal infection; causes anal pruritis
Toxoplasma gondii
Schistosoma
Colonic epithelial cell necrosis and stimulation of fibrin deposition
Enterobius vermicularis

24. Inflammation of muscle (larvae encyst in muscle)
Yellow fever
EBV
Trichinella spiralis
Taenid solium

25. Enterotoxin A
EBV
C. Difficile
Mycobacterium avium - intracellulare
T. pertenue

26. Flavivirus
Enveloped - SS+ - linear - icosahedral
Schistosoma haematobium
Icosohedral (double)
Cryptococcus neoformans

27. HIV - Superficial neoplastic proliferation of vasculature; biopsy reveals lymphocytic inflammation
Group A streptococcus. Helps prevent phagocytosis.
Praziquantel
HHV-8
Sodium stibogluconate

28. Kala - azar: spiking fevers - hepatosplenomegaly - pancytopenia
Leishmania donovani
Wuchereria bancrofti
Rubella
Enveloped - SS - - circular - helical

29. Undercooked crab meat; causes inflammation and secondary bacterial infection of the lung - causing hemoptysis
Rubeola
Topical miconazole - selenium sulfide
Bunyavirus - hemorrhagic fever - pneumonia
Paragonimus westermani

30. Rubella
Loa Loa
Amphotericin B
Togavirus
HPV

31. Pinworm
Enterobius vermicularis
Colonic epithelial cell necrosis and stimulation of fibrin deposition
Rubella
ADP ribosylating A- B toxin inactivates EF-2

32. Coxackievirus
Picornavirus
Togavirus
Amphotericin B
Aseptic meningitis - herpangina - mycarditis

33. Tx for Taenid solium
Trichinella spiralis
Bunyavirus
Praziquantel
Fluconazole or ketoconazole

34. HIV - Chronic watery diarrhea; acid - fast cysts seen in stool
Rifampin
Nonenveloped - SS + - Icosahedral
Cryptosporidium spp.
Diphyllobothrium latum

35. Parainfluenza - croup
Enveloped - SS - - linear - Helical
Paramyxovirus
Picornavirus
Enveloped - SS+ - linear - icosahedral

36. Warthin - Finkeldy giant cell
Pathognomonic for measles or live attenuated vaccine
Bacterial chromosome
Taenid solium
Enveloped - SS - - linear - Helical

37. Transmitted by female blackflies; causes hyperpigmented skin. Can have allergic reaction to microfilaria
Cryptococcus neoformans
Diethylcarbamazine
Palivizumab
Onchocerca volvulus

38. Tx for Toxocara canis
Enveloped - SS + - Icosahedral
Enterobius vermicularis
Diethylcarbamazine
HPV

39. Shiga toxin: Plasmid - lysogeny - bacterial chromosome?
Ascaris lumbricoides
Bacterial chromosome
DS linear 10-12 segments
Toxoplasma gondii

40. HDV
Icosohedral (double)
Paramyxovirus
Deltavirus
Picornavirus

41. IgA protease
Cleaves IgA. S. pneumoniae - H. influenzae type B - Neisseria (SHiN) in order to colonize respiratory mucosa.
Bunyavirus
Rubella
Fluconazole or ketoconazole

42. Fever and hemolytic anemia; predominantly in NE USA
Schistosoma
Congenital Toxoplasma gondii
Babesia
Group A streptococcus. Helps prevent phagocytosis.

43. Reovirus
Aseptic meningitis - herpangina - mycarditis
Arenavirus
Reovirus
Icosohedral (double)

44. Ocular problems (cataracts - retinopathy - micropthalmos - glaucoma) - cardiovascular problems (PDA - VSD - pulmonary stenosis) - deafness - thrombocytopenia purpura - hepatosplenomegaly - CNS problems - bony lesions
Retrovirus
Sodium stibogluconate
Clonorchis sinensis
Congenital rubella

45. HAV
Watery diarrhea
Yellow fever
Picornavirus
Bacterial chromosome

46. Food contaminated with eggs; causes granulomas (in in retina -> blindness) and visceral larva migrans
Doxycycline - ceftriaxone
Paramyxovirus
Rubella
Toxocara canis

47. Mumps
Paramyxovirus
Enveloped - SS - - circular - 2 segments - helical
Picornavirus
CMV

48. Alpha toxin
Deltavirus
Clostridium difficile - gas gangrene - double zone of hemolysis on blood agar
Flavivirus
Ancylostoma - Necator

49. Maltese cross in RBC
Lysogeny
Icosohedral (double)
Babesia
Cryptosporidium spp.

50. RSV
Stains cryptococcus neoformans red
Paramyxovirus
JC virus (PML) results in demyelination
Echinococcus granulosus

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Microbiology 2

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