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Microbiology 2

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Snails are host
Rubella
EBV
Schistosoma
Trichomonas vaginalis

2. Food contaminated with eggs; causes granulomas (in in retina -> blindness) and visceral larva migrans
Nifurtimox
Flavivirus
Toxocara canis
Trichinella spiralis

3. Coronaviruses
Pseudomonas - inactivates EF-2
Enveloped - SS + - Icosahedral
Flavivirus
Enveloped - SS - - circular - helical

4. Western equine encephalitis
Togavirus
Pasteurella multocida
Taenid solium
No envelope

5. Coxackievirus
Aseptic meningitis - herpangina - mycarditis
Colonic epithelial cell necrosis and stimulation of fibrin deposition
Mucor or Rhizopus spp.
Arenavirus

6. Parasite: Portal hypertension
Itraconazole or potassium iodide
Schistosoma mansoni
Lysogeny
Praziquantel

7. Arenaviruses
P. vivax/ovale
Enveloped - SS - - circular - 2 segments - helical
Topical miconazole - selenium sulfide
Mucor or Rhizopus spp.

8. Pinworm
Cleaves IgA. S. pneumoniae - H. influenzae type B - Neisseria (SHiN) in order to colonize respiratory mucosa.
Doxycycline - ceftriaxone
Enterobius vermicularis
Enveloped - SS - - circular - helical

9. HIV - Pneumonia CD4<200
Cleaves host cell rRNA (inactivates 60S ribosome); enhances cytokine release - causing HUS.
Pneumocystis jiroveci
Nystatin
Schistosoma

10. Triad of chorioretinitis - hydrocephalus - intracranial calcifications
Filovirus
Ancylostoma duodenale - Necator americanus
ADP ribosylating A- B toxin inactivates EF-2
Congenital Toxoplasma gondii

11. Tx of Clonorchis sinensis
Pneumocystis jiroveci
Praziquantel
Toxoplasma gondii
Doxycycline - ceftriaxone

12. Protozoa: Rapidly fatal meningoencephalitis
Naegleria fowleri
Praziquantel
Togavirus
Paramyxovirus

13. Treatment for Haemophilus influenzae meningitis
Ceftriaxone
Enveloped - SS - - linear - Helical
Filovirus
Topical miconazole - selenium sulfide

14. Kala - azar: spiking fevers - hepatosplenomegaly - pancytopenia
Diphyllobothrium latum
Naegleria fowleri
Leishmania donovani
Enveloped - SS+ - linear - icosahedral

15. Parasite: Hematuria - bladder CA
Calicivirus
Schistosoma haematobium
Ribavirin
Enterobius vermicularis

16. Fever and hemolytic anemia; predominantly in NE USA
Babesia
Coxiella burnetti
Picornavirus
Filovirus

17. HIV - Chronic watery diarrhea; acid - fast cysts seen in stool
Mucor or Rhizopus spp.
Cryptosporidium spp.
Yellow fever
Trichinella spiralis

18. Maltese cross in RBC
EBV
Enveloped - SS - - linear - Helical
HHV-6 (Roseola)
Babesia

19. Rhabdoviruses
Pneumocystis jiroveci
Enveloped - SS - - linear - nonsegmented - Helical
Pathognomonic for measles or live attenuated vaccine
Enveloped - SS - - linear - Helical

20. Poliovirus
Enveloped - SS+ - linear - icosahedral
Rubeola
Picornavirus
Clonorchis sinensis

21. dsRNA segmented virus
Nonenveloped - SS + - Icosahedral
Clonorchis sinensis
Clonorchis sinensis
Reovirus

22. Ebola/Marburg hemorrhagic fever
Cryptosporidium spp.
Diethylcarbamazine
S. aureus. Binds Fc region of Ig. Prevents opsonization and phagocytosis.
Filovirus

23. M protein
Group A streptococcus. Helps prevent phagocytosis.
CMV
Toxoplasma gondii
EBV

24. Lassa fever encephalitis
Reovirus
Lysogeny
Arenavirus - spread by mice
S. aureus. Binds Fc region of Ig. Prevents opsonization and phagocytosis.

25. West nile virus
HPV
Flavivirus
Toxocara canis
Paramyxoviruses

26. Undercooked meat (pork)
Group A streptococcus. Helps prevent phagocytosis.
Rubeola
Picornavirus
Trichinella spiralis

27. Sandfly/Rift valley fevers
Paramyxovirus
Bunyavirus
Group A streptococcus. Helps prevent phagocytosis.
Trichinella spiralis

28. Eastern equine encephalitis
Bartonella henselae (bacillary angiomatosis)
Togavirus
Yellow fever
Bacterial chromosome

29. Tx of Paragonimus westermani
Rubella
No envelope - SS + linear - Icosahedral
Palivizumab
Praziquantel

30. Generalized lymphadenopathy particularly postauricular and occipital
Rubella
Enveloped - SS - - linear - Helical
Toxoplasma gondii
Loa Loa

31. Protozoa: Severe diarrhea in AIDS - mild dz in non - immunocompromised
Amphotericin B
Bunyavirus
Onchocerca volvulus
Cryptosporidium

32. 'swiss cheese' appearance in brain
Paragonimus westermani
Enveloped - SS+ - linear - icosahedral
Bartonella henselae (bacillary angiomatosis)
Taenid solium

33. Tx for Taenid solium
Group A beta - hemolytic strep (S. pyogenes) sensitive. Group B (S. agalactiae) resistant.
ADP ribosylating A- B toxin inactivates EF-2
Praziquantel
Reovirus

34. Retroviruses
Enveloped - SS + - Icosahedral
Reovirus
Bunyavirus
Mucor or Rhizopus spp.

35. Ingestion of larvae in raw freshwater fish. Causes vitamin B12 defic anemia.
Topical miconazole - selenium sulfide
Clonorchis sinensis
Cryptosporidium spp.
Diphyllobothrium latum

36. Reovirus
No envelope
T. pertenue
Bunyavirus - hemorrhagic fever - pneumonia
Most common cause of aseptic meningitis

37. Tx for Trypanosoma cruzi
Trichinella spiralis
Lysogeny
Nifurtimox
S. aureus. Binds Fc region of Ig. Prevents opsonization and phagocytosis.

38. RSV
Loa Loa
Rubella
Aminoglycoside plus extended spectrum penicillin (piperacillin - ticarcillin)
Paramyxovirus

39. Mumps
Rubeola
Paramyxovirus
ADP ribosylating A- B toxin inactivates EF-2
Group A streptococcus. Helps prevent phagocytosis.

40. Reovirus
Coxiella burnetti
Enveloped - SS+ - linear - icosahedral
bendazoles
DS linear 10-12 segments

41. Tx for RSV
Fluconazole or ketoconazole
Ribavirin
Ascaris lumbricoides
Watery diarrhea

42. Ingestion of larvae encysted in undercooked pork. Cysticercosis and neurocysticercosis - mass lesions in brain.
JC virus (PML) results in demyelination
Taenid solium
Diethylcarbamazine
EBV

43. Yellow fever
Trypanosoma (T. gambiense - T. rhodiesiense); African sleeping sickness
Entamoeba histolytica
Enveloped - SS + - Icosahedral
Flavivirus

44. HIV - Meningitis; India ink stain reveals narrow - based budding
Cryptococcus neoformans
Pneumocystis jiroveci
bendazoles
Picornavirus

45. Colorado tick fever
Bunyavirus
Trichomonas vaginalis
Trichinella spiralis
Reovirus

46. Councilman bodies (acidophilic inclusions) in liver
Group A streptococcus. Helps prevent phagocytosis.
Yellow fever
Praziquantel
Diphyllobothrium latum

47. Rhinovirus
Enveloped - SS+ - linear - icosahedral
Clonorchis sinensis
Yellow fever
Picornavirus

48. Parasite: Microcytic anemia
S. pneumoniae sensitive - S. viridans resistant
Giardia lamblia
Ancylostoma - Necator
Pneumocystis jiroveci

49. Food contaminated with eggs; intestinal infection; causes anal pruritis
Praziquantel
Enterobius vermicularis
Trichinella spiralis
Paramyxovirus

50. Warthin - Finkeldy giant cell
Pathognomonic for measles or live attenuated vaccine
No envelope - SS + linear - Icosahedral
Entamoeba histolytica
Enveloped - SS - - linear - 8 segments - Helical