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Microbiology 2

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Exotoxin A
Colonic epithelial cell necrosis and stimulation of fibrin deposition
Arenavirus - spread by mice
Pseudomonas - inactivates EF-2
Paramyxovirus

2. Fever and hemolytic anemia; predominantly in NE USA
Most common cause of aseptic meningitis
Deltavirus
Enveloped - SS - - linear - Helical
Babesia

3. Transmitted by deer fly - horse fly - and mango fly; causes swelling in skin (can see worm crawling in conjunctiva)
DS linear 10-12 segments
Picornavirus
Babesia
Loa Loa

4. IgA protease
Cleaves IgA. S. pneumoniae - H. influenzae type B - Neisseria (SHiN) in order to colonize respiratory mucosa.
Rubella
Reovirus
Amphotericin B

5. HCV
Flavivirus
Cleaves host cell rRNA (inactivates 60S ribosome); enhances cytokine release - causing HUS.
Strongyloides stercoralis
Clonorchis sinensis

6. Tx of Paragonimus westermani
P. vivax/ovale
Enveloped - SS - - circular - helical
Ancylostoma - Necator
Praziquantel

7. Cycles occuring every other day; dormant form in liver -> tx w/primaquine
Naegleria fowleri
Reovirus
P. vivax/ovale
Doxycycline - ceftriaxone

8. Undercooked meat (pork)
S. pneumoniae sensitive - S. viridans resistant
DS linear 10-12 segments
Trichinella spiralis
Bunyavirus

9. Parasite: Hematuria - bladder CA
Invasive aspergillosis
Flavivirus
Schistosoma haematobium
Diethylcarbamazine

10. Rhinovirus
Pseudomonas - inactivates EF-2
Ceftriaxone
Picornavirus
Ascaris lumbricoides

11. Ingestion of larvae in raw freshwater fish. Causes vitamin B12 defic anemia.
Lysogeny
bendazoles
Diphyllobothrium latum
Watery diarrhea

12. Coxackievirus
Ivermectin
Aseptic meningitis - herpangina - mycarditis
Paramyxovirus
Togavirus

13. Reovirus
Enveloped - SS - - linear - Helical
Filovirus
Cryptococcus neoformans
Icosohedral (double)

14. Bacitracin
Lysogeny
Paramyxovirus
Group A beta - hemolytic strep (S. pyogenes) sensitive. Group B (S. agalactiae) resistant.
P. vivax/ovale

15. HTLV
Ascaris lumbricoides
Loa Loa
Retrovirus
Paramyxovirus

16. Treatment for systemic candida infection
Amphotericin B
Clonorchis sinensis
Trichinella spiralis
Nifurtimox

17. Orthomyxoviruses
Cryptococcus neoformans
Itraconazole or potassium iodide
Picornavirus
Enveloped - SS - - linear - 8 segments - Helical

18. Councilman bodies (acidophilic inclusions) in liver
EBV
Yellow fever
JC virus (PML) results in demyelination
Cleaves host cell rRNA (inactivates 60S ribosome); enhances cytokine release - causing HUS.

19. Calicivirus
Enveloped - SS - - linear - nonsegmented - Helical
No envelope - SS + linear - Icosahedral
Onchocerca volvulus
Rubeola

20. Eastern equine encephalitis
Togavirus
Paramyxovirus
Picornavirus
P. vivax/ovale

21. Undercooked fish
Cryptococcus neoformans
Clonorchis sinensis
Amphotericin B
Toxoplasma gondii

22. Parasite: Microcytic anemia
Diethylcarbamazine
Ancylostoma - Necator
HHV-6 (Roseola)
Pneumocystis jiroveci

23. HIV - Superficial neoplastic proliferation of vasculature; biopsy reveals lymphocytic inflammation
HPV
Picornavirus
Colonic epithelial cell necrosis and stimulation of fibrin deposition
HHV-8

24. Dilated cardiomyopathy - megacolon - megaesophagus
Heart block - bilateral Bell's palsy
Colonic epithelial cell necrosis and stimulation of fibrin deposition
Echinococcus granulosus
Trypansoma cruzi. Chagas dz - S. America

25. HIV - TB like dz CD4<50
Watery diarrhea
Praziquantel
Enveloped - SS - - linear - nonsegmented - Helical
Mycobacterium avium - intracellulare

26. HDV
Trichinella spiralis
Toxocara canis
CMV
Deltavirus

27. Enlarged lymph nodes - recurring fever (d/t Ag variation) - somnolence - coma
P. falciparum
Schistosoma
Diethylcarbamazine
Trypanosoma (T. gambiense - T. rhodiesiense); African sleeping sickness

28. Tx for neurocystercercosis
bendazoles
Toxoplasma gondii
Picornavirus
Pneumocystis jiroveci

29. Prophylaxis in close contacts of pts w/Haemophilus influenzae meningitis
Topical miconazole - selenium sulfide
Praziquantel
Rifampin
Orthomyxovirus

30. Protozoa: Severe diarrhea in AIDS - mild dz in non - immunocompromised
Arenavirus
Toxoplasma gondii
Aseptic meningitis - herpangina - mycarditis
Cryptosporidium

31. Treatment for Sporothrix schenckii
Itraconazole or potassium iodide
Cleaves host cell rRNA (inactivates 60S ribosome); enhances cytokine release - causing HUS.
Coxackie A - syphilis - Rocky Mountain spotted fever
Praziquantel

32. Undercooked crab meat; causes inflammation and secondary bacterial infection of the lung - causing hemoptysis
Paragonimus westermani
Schistosoma
CMV
Arenavirus - spread by mice

33. Tx for Toxocara canis
Diethylcarbamazine
Enveloped - SS + - Icosahedral
Trichinella spiralis
S. aureus. Binds Fc region of Ig. Prevents opsonization and phagocytosis.

34. Eaton's agar
Mycoplasma pneumonia
Onchocerca volvulus
Yellow fever
No envelope

35. California encephalitis
Trypansoma cruzi. Chagas dz - S. America
Bunyavirus
Paramyxovirus
Praziquantel

36. Triad of chorioretinitis - hydrocephalus - intracranial calcifications
Congenital Toxoplasma gondii
bendazoles
Trypanosoma (T. gambiense - T. rhodiesiense); African sleeping sickness
Cleaves IgA. S. pneumoniae - H. influenzae type B - Neisseria (SHiN) in order to colonize respiratory mucosa.

37. Kala - azar: spiking fevers - hepatosplenomegaly - pancytopenia
Cryptococcus neoformans
Leishmania donovani
Lysogeny
Enveloped - SS - - circular - 3 segments - helical

38. Rubeola
Picornavirus
Paramyxovirus
Itraconazole or potassium iodide
Yellow fever

39. Eggs visible in feces; intestinal infection
Ascaris lumbricoides
C. Difficile
Bunyavirus
Trichinella spiralis

40. Hepevirus
No envelope - SS + linear - Icosahedral
HPV
Ceftriaxone
Clostridium difficile - gas gangrene - double zone of hemolysis on blood agar

41. Maltese cross in RBC
Babesia
Enveloped - SS + - Icosahedral
No envelope - SS + linear - Icosahedral
Pathognomonic for measles or live attenuated vaccine

42. Warthin - Finkeldy giant cell
Diethylcarbamazine
Toxoplasma gondii
Rubeola
Pathognomonic for measles or live attenuated vaccine

43. Mucicarmine
Pneumocystis jiroveci
Stains cryptococcus neoformans red
P. vivax/ovale
Dracunculus medinensis

44. St. Louis encephalitis
Flavivirus
Enveloped - SS - - circular - 2 segments - helical
Clonorchis sinensis
Toxoplasma gondii

45. Tx for Onchocerca volvulus
Cryptococcus neoformans
Ivermectin
Paramyxovirus
Diethylcarbamazine

46. High fever - black vomitus - jaundice
EBV
Calicivirus
Yellow fever
Nifurtimox

47. Cercariae penetrate skin of humans; causes granulomas - fibrosis - and inflammation of the spleen and liver. Chronic infection can lead to squamous cell carcinoma of the bladder.
Schistosoma
Bartonella henselae (bacillary angiomatosis)
C. Difficile
No envelope - SS + linear - Icosahedral

48. Protozoa: Brain abscess in HIV
S. pneumoniae sensitive - S. viridans resistant
S. epidermidis sensitive. S. saprophyticus resistant.
Toxoplasma gondii
Enveloped - SS - - linear - nonsegmented - Helical

49. Tx for Echinococcus granulosus
bendazoles
Cryptosporidium spp.
Loa Loa
Cleaves host cell rRNA (inactivates 60S ribosome); enhances cytokine release - causing HUS.

50. Opportunistic fungal infection in ketoacidotic diabetic or leukemic patients
Loa Loa
Togavirus
Mucor or Rhizopus spp.
Trichinella spiralis