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Microbiology 2

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Reovirus
Paramyxoviruses
Cleaves IgA. S. pneumoniae - H. influenzae type B - Neisseria (SHiN) in order to colonize respiratory mucosa.
Group A streptococcus. Helps prevent phagocytosis.
Icosohedral (double)

2. HIV - Interstitial pneumonia; biopsy reveals cells with intranuclear and cytoplasmic inclusion bodies
CMV
Picornavirus
Aminoglycoside plus extended spectrum penicillin (piperacillin - ticarcillin)
Paramyxovirus

3. Rhinovirus
Stains cryptococcus neoformans red
Picornavirus
Schistosoma haematobium
Enveloped - SS+ - linear - icosahedral

4. Tx of Paragonimus westermani
Diethylcarbamazine
EBV
Loa Loa
Praziquantel

5. All contain surface F 'fusion' protein
Picornavirus
Enveloped - SS+ - linear - icosahedral
Filovirus
Paramyxoviruses

6. Filoviruses
JC virus (PML) results in demyelination
Paramyxovirus
Enveloped - SS - - linear - Helical
Paragonimus westermani

7. Rubeola
Flavivirus
Paramyxovirus
Paramyxoviruses
Erythromycin

8. Severe; daily cycles; parasitized RBCs occlude capillaries in brain - kidneys - lungs
Nonenveloped - SS + - Icosahedral
Nifurtimox
Paramyxovirus
P. falciparum

9. M protein
Calicivirus
Group A streptococcus. Helps prevent phagocytosis.
No envelope - SS + linear - Icosahedral
CMV

10. HIV - Chronic watery diarrhea; acid - fast cysts seen in stool
Lysogeny
Most common cause of aseptic meningitis
Cryptosporidium spp.
Enveloped - SS - - circular - helical

11. Pinworm
Enterobius vermicularis
Diphyllobothrium latum
Naegleria fowleri
Pathognomonic for measles or live attenuated vaccine

12. River blindness
Reovirus
Pasteurella multocida
Togavirus
Onchocerca volvulus

13. dsRNA segmented virus
Rifampin
Most common cause of aseptic meningitis
Reovirus
Aminoglycoside plus extended spectrum penicillin (piperacillin - ticarcillin)

14. 'swiss cheese' appearance in brain
Sodium stibogluconate
Taenid solium
Nifurtimox
Cryptococcus neoformans

15. Hookworms
P. vivax/ovale
Quinine - clindamycin
Necator americanus
Rubella

16. Rotavirus
Trichinella spiralis
Rubeola
Reovirus
Amphotericin B

17. 3- day rash
Rubella
Cleaves host cell rRNA (inactivates 60S ribosome); enhances cytokine release - causing HUS.
Topical miconazole - selenium sulfide
Clonorchis sinensis

18. Ebola/Marburg hemorrhagic fever
Bacterial chromosome
EBV
Flavivirus
Filovirus

19. Tx for Pseudomonas aeruginosa
Flavivirus
Trichinella spiralis
Aminoglycoside plus extended spectrum penicillin (piperacillin - ticarcillin)
C. Difficile

20. Erythrogenic exotoxin of strep pyogenes: Plasmid - lysogeny - bacterial chromosome?
Necator americanus
Praziquantel
Onchocerca volvulus
Lysogeny

21. Protozoa: Brain abscess in HIV
Trypansoma cruzi. Chagas dz - S. America
Aseptic meningitis - herpangina - mycarditis
Toxoplasma gondii
Enveloped - SS - - linear - 8 segments - Helical

22. Treatment for Sporothrix schenckii
Schistosoma haematobium
Taenid solium
Itraconazole or potassium iodide
Congenital Toxoplasma gondii

23. 'Soap bubble' lesion in brain
Metronidazole
Cryptococcus neoformans
Trichinella spiralis
Schistosoma haematobium

24. Fever then rash
Toxoplasma gondii
C. Difficile
Colonic epithelial cell necrosis and stimulation of fibrin deposition
HHV-6 (Roseola)

25. Transmitted by female blackflies; causes hyperpigmented skin. Can have allergic reaction to microfilaria
Onchocerca volvulus
No envelope - SS + linear - Icosahedral
Retrovirus
Calicivirus

26. Hantavirus
Bunyavirus - hemorrhagic fever - pneumonia
Clostridium difficile - gas gangrene - double zone of hemolysis on blood agar
ADP ribosylating A- B toxin inactivates EF-2
Enveloped - SS - - circular - 2 segments - helical

27. Picornaviruses
Picornavirus
S. aureus. Binds Fc region of Ig. Prevents opsonization and phagocytosis.
Mucor or Rhizopus spp.
Nonenveloped - SS + - Icosahedral

28. Maltese cross in RBC
Rubella
Babesia
Trichomonas vaginalis
Togavirus

29. Tx for Wuchereria bancrofti
Diethylcarbamazine
Reovirus
S. aureus. Binds Fc region of Ig. Prevents opsonization and phagocytosis.
Echinococcus granulosus

30. Western equine encephalitis
Leishmania donovani
Itraconazole or potassium iodide
Togavirus
ADP ribosylating A- B toxin inactivates EF-2

31. Transmitted by deer fly - horse fly - and mango fly; causes swelling in skin (can see worm crawling in conjunctiva)
EBV
Cryptosporidium spp.
Reovirus
Loa Loa

32. Eastern equine encephalitis
Ancylostoma duodenale - Necator americanus
Mucor or Rhizopus spp.
Enveloped - SS - - linear - 8 segments - Helical
Togavirus

33. C. tetani exotoxin: Plasmid - lysogeny - bacterial chromosome?
Clostridium difficile - gas gangrene - double zone of hemolysis on blood agar
Trichinella spiralis
Yellow fever
Plasmid

34. Cellulitis from animal bite
Nystatin
Pasteurella multocida
Cryptococcus neoformans
Heart block - bilateral Bell's palsy

35. Undercooked crab meat; causes inflammation and secondary bacterial infection of the lung - causing hemoptysis
Paragonimus westermani
Reovirus
Picornavirus
Ribavirin

36. Exotoxin A
C. Difficile
Invasive aspergillosis
Pseudomonas - inactivates EF-2
P. vivax/ovale

37. Reovirus
Enterobius vermicularis
No envelope
Wuchereria bancrofti
HHV-8

38. Treatment for local infection by systemic mycoses
Calicivirus
Fluconazole or ketoconazole
Reovirus
ADP ribosylating A- B toxin inactivates EF-2

39. Tx for Taenid solium
Sodium stibogluconate
Praziquantel
Enterobius vermicularis
Picornavirus

40. Botulinum exotoxin: Plasmid - lysogeny - bacterial chromosome?
Nystatin
Picornavirus
Palivizumab
Lysogeny

41. Protozoa: Severe diarrhea in AIDS - mild dz in non - immunocompromised
S. pneumoniae sensitive - S. viridans resistant
Bacterial chromosome
Fluconazole or ketoconazole
Cryptosporidium

42. Shiga toxin: Plasmid - lysogeny - bacterial chromosome?
Trichomonas vaginalis
Rubeola
Bacterial chromosome
Togavirus

43. Kala - azar: spiking fevers - hepatosplenomegaly - pancytopenia
Fluconazole or ketoconazole
Leishmania donovani
Enveloped - SS + - Icosahedral
Enveloped - SS - - linear - Helical

44. Sandfly/Rift valley fevers
Diethylcarbamazine
Picornavirus
Clonorchis sinensis
Bunyavirus

45. Colorado tick fever
P. vivax/ovale
Reovirus
Lysogeny
Nifurtimox

46. California encephalitis
Cleaves IgA. S. pneumoniae - H. influenzae type B - Neisseria (SHiN) in order to colonize respiratory mucosa.
Bunyavirus
Togavirus
P. vivax/ovale

47. Causes inflammation of the biliary tract -> pigmented gallstones
S. pneumoniae sensitive - S. viridans resistant
Onchocerca volvulus
Most common cause of aseptic meningitis
Clonorchis sinensis

48. Prophylaxis in close contacts of pts w/Haemophilus influenzae meningitis
Bunyavirus
Filovirus
Rifampin
Cryptococcus neoformans

49. Tx for Loa Loa
Bunyavirus - hemorrhagic fever - pneumonia
Ribavirin
Flavivirus
Diethylcarbamazine

50. Cercariae penetrate skin of humans; causes granulomas - fibrosis - and inflammation of the spleen and liver. Chronic infection can lead to squamous cell carcinoma of the bladder.
Doxycycline - ceftriaxone
Necator americanus
Rubeola
Schistosoma