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Microbiology 2

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Parasite: Hematuria - bladder CA
Nifurtimox
Trichinella spiralis
Schistosoma haematobium
S. epidermidis sensitive. S. saprophyticus resistant.

2. HCV
Enveloped - SS - - linear - Helical
Lysogeny
Rubeola
Flavivirus

3. HIV - Chronic watery diarrhea; acid - fast cysts seen in stool
Cryptococcus neoformans
Cryptosporidium spp.
Trypanosoma (T. gambiense - T. rhodiesiense); African sleeping sickness
Praziquantel

4. Rhabdoviruses
Enveloped - SS - - circular - 2 segments - helical
Diethylcarbamazine
Enveloped - SS - - linear - Helical
Schistosoma

5. Echovirus
bendazoles
Most common cause of aseptic meningitis
Stains cryptococcus neoformans red
Paramyxovirus

6. HIV - Non - hodgkin's lymphoma (large cell type); often on oropharynx (Waldeyer's ring)
Cryptosporidium spp.
Bunyavirus
EBV
Trichomonas vaginalis

7. Deltaviruses
P. vivax/ovale
Rubella
Schistosoma
Enveloped - SS - - circular - helical

8. Reovirus
Toxoplasma gondii
Icosohedral (double)
Echinococcus granulosus
Heart block - bilateral Bell's palsy

9. Causes inflammation of the biliary tract -> pigmented gallstones
Nonenveloped - SS + - Icosahedral
Arenavirus
Clonorchis sinensis
Reovirus

10. Reovirus
Enterobius vermicularis
DS linear 10-12 segments
Picornavirus
Group A beta - hemolytic strep (S. pyogenes) sensitive. Group B (S. agalactiae) resistant.

11. Parasite: Portal hypertension
Clostridium difficile - gas gangrene - double zone of hemolysis on blood agar
Bartonella henselae (bacillary angiomatosis)
Schistosoma mansoni
Rubeola

12. Influenza virus
Trichinella spiralis
Orthomyxovirus
Diphyllobothrium latum
Lysogeny

13. Rotavirus
Coxackie A - syphilis - Rocky Mountain spotted fever
Reovirus
Ascaris lumbricoides
Rubella

14. HIV - Hairy leukoplakia; often on lateral tongue
Itraconazole or potassium iodide
EBV
Reovirus
Giardia lamblia

15. Undercooked crab meat; causes inflammation and secondary bacterial infection of the lung - causing hemoptysis
Paragonimus westermani
Aminoglycoside plus extended spectrum penicillin (piperacillin - ticarcillin)
Rubella
Heart block - bilateral Bell's palsy

16. Enterotoxin A
Nystatin
Enveloped - SS - - linear - nonsegmented - Helical
C. Difficile
Invasive aspergillosis

17. Tx for Legionella pneumophila
Pneumocystis jiroveci
Erythromycin
Flavivirus
S. pneumoniae sensitive - S. viridans resistant

18. HIV - Meningitis; India ink stain reveals narrow - based budding
Praziquantel
Rubeola
Deltavirus
Cryptococcus neoformans

19. Transmitted by female blackflies; causes hyperpigmented skin. Can have allergic reaction to microfilaria
Onchocerca volvulus
No envelope - SS + linear - Icosahedral
Fluconazole or ketoconazole
Trichinella spiralis

20. Coxackievirus
Picornavirus
Wuchereria bancrofti
Togavirus
Paragonimus westermani

21. Tx of Paragonimus westermani
Wuchereria bancrofti
Praziquantel
Rubeola
Nonenveloped - SS + - Icosahedral

22. Ebola/Marburg hemorrhagic fever
Togavirus
Retrovirus
DS linear 10-12 segments
Filovirus

23. Cellulitis from animal bite
Picornavirus
Flavivirus
Pasteurella multocida
Cryptosporidium

24. Undercooked meat (pork)
Doxycycline - ceftriaxone
Bacterial chromosome
Trichinella spiralis
Strongyloides stercoralis

25. Togavirus
Clostridium difficile - gas gangrene - double zone of hemolysis on blood agar
Mucor or Rhizopus spp.
Flavivirus
Enveloped - SS+ - linear - icosahedral

26. Poliovirus
Ancylostoma - Necator
Trypansoma cruzi. Chagas dz - S. America
Picornavirus
Amphotericin B

27. Eggs visible in feces; intestinal infection
Heart block - bilateral Bell's palsy
Cryptosporidium
Rubeola
Ascaris lumbricoides

28. Tx of Schistosoma
ADP ribosylating A- B toxin inactivates EF-2
Pathognomonic for measles or live attenuated vaccine
Praziquantel
Aminoglycoside plus extended spectrum penicillin (piperacillin - ticarcillin)

29. Triad of chorioretinitis - hydrocephalus - intracranial calcifications
No envelope
Congenital Toxoplasma gondii
Praziquantel
Flavivirus

30. Hepevirus
No envelope - SS + linear - Icosahedral
Enveloped - SS+ - linear - icosahedral
Bunyavirus
S. pneumoniae sensitive - S. viridans resistant

31. Tx for Diphyllobothrium latum
Mucor or Rhizopus spp.
Schistosoma mansoni
Watery diarrhea
Praziquantel

32. Coxackievirus
Onchocerca volvulus
Itraconazole or potassium iodide
Schistosoma
Aseptic meningitis - herpangina - mycarditis

33. Cycles occuring every other day; dormant form in liver -> tx w/primaquine
P. vivax/ovale
C. Difficile
Fluconazole or ketoconazole
Togavirus

34. Treatment for Haemophilus influenzae meningitis
No envelope - SS + linear - Icosahedral
Praziquantel
Ceftriaxone
Toxoplasma gondii

35. Ingestion of larvae in raw freshwater fish. Causes vitamin B12 defic anemia.
Diphyllobothrium latum
Lysogeny
Rubeola
Ascaris lumbricoides

36. Opportunistic fungal infection in ketoacidotic diabetic or leukemic patients
Cleaves IgA. S. pneumoniae - H. influenzae type B - Neisseria (SHiN) in order to colonize respiratory mucosa.
Aseptic meningitis - herpangina - mycarditis
Toxoplasma gondii
Mucor or Rhizopus spp.

37. Protozoa: Rapidly fatal meningoencephalitis
S. epidermidis sensitive. S. saprophyticus resistant.
Amphotericin B
C. Difficile
Naegleria fowleri

38. Protozoa: Bloody diarrhea - liver abscess - RUQ pain
Giardia lamblia
Mucor or Rhizopus spp.
Enveloped - SS - - linear - 8 segments - Helical
Entamoeba histolytica

39. Diphtheria toxin: Plasmid - lysogeny - bacterial chromosome?
Lysogeny
Echinococcus granulosus
Enveloped - SS - - linear - Helical
Entamoeba histolytica

40. Tx for RSV
Ribavirin
Diethylcarbamazine
Flavivirus
Enveloped - SS - - circular - 2 segments - helical

41. Undercooked fish
Flavivirus
Clonorchis sinensis
EBV
Plasmid

42. Coronaviruses
Paramyxoviruses
Coxackie A - syphilis - Rocky Mountain spotted fever
Trichinella spiralis
Enveloped - SS + - Icosahedral

43. Botulinum exotoxin: Plasmid - lysogeny - bacterial chromosome?
Lysogeny
Trichomonas vaginalis
Cryptosporidium spp.
Onchocerca volvulus

44. O Ag of Salmonella: Plasmid - lysogeny - bacterial chromosome?
Deltavirus
Clonorchis sinensis
ADP ribosylating A- B toxin inactivates EF-2
Lysogeny

45. Mumps
Paramyxovirus
Enveloped - SS+ - linear - icosahedral
CMV
Arenavirus

46. Enterotoxin A
P. vivax/ovale
Most common cause of aseptic meningitis
Topical miconazole - selenium sulfide
Watery diarrhea

47. River blindness
Onchocerca volvulus
Cryptosporidium
Rubella
Rifampin

48. Rhinovirus
Invasive aspergillosis
Paramyxovirus
Picornavirus
Palivizumab

49. Eggs in dog feces when ingested can cause cysts in liver; causes anaphylaxis if Ags are released from cysts (surgeons inject ethanol before removal to neutralize Ags).
Flavivirus
Cleaves host cell rRNA (inactivates 60S ribosome); enhances cytokine release - causing HUS.
Echinococcus granulosus
Bunyavirus

50. Shiga toxin
Cleaves host cell rRNA (inactivates 60S ribosome); enhances cytokine release - causing HUS.
Erythromycin
Topical miconazole - selenium sulfide
DS linear 10-12 segments