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Microbiology 2

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Orthomyxoviruses
Group A beta - hemolytic strep (S. pyogenes) sensitive. Group B (S. agalactiae) resistant.
Cryptosporidium
Enveloped - SS - - linear - 8 segments - Helical
Loa Loa

2. Tx of Schistosoma
Praziquantel
Erythromycin
Schistosoma mansoni
Retrovirus

3. Protozoa: Bloating - flatulence - foul - smelling - fatty diarrhea
Giardia lamblia
Lysogeny
Cryptococcus neoformans
Rifampin

4. Transmitted by female blackflies; causes hyperpigmented skin. Can have allergic reaction to microfilaria
Onchocerca volvulus
Amphotericin B
Enveloped - SS - - circular - helical
S. epidermidis sensitive. S. saprophyticus resistant.

5. Rotavirus
Cryptosporidium spp.
Reovirus
Echinococcus granulosus
Orthomyxovirus

6. HIV - Pleuritic pain - hemoptysis - infiltrates on imaging
Stains cryptococcus neoformans red
Enterobius vermicularis
Invasive aspergillosis
Reovirus

7. 5- day rash
Trypanosoma (T. gambiense - T. rhodiesiense); African sleeping sickness
Rubeola
Schistosoma mansoni
Cleaves host cell rRNA (inactivates 60S ribosome); enhances cytokine release - causing HUS.

8. Causes inflammation of the biliary tract -> pigmented gallstones
Erythromycin
Clonorchis sinensis
Enveloped - SS - - linear - nonsegmented - Helical
Enveloped - SS + - Icosahedral

9. Coronaviruses
No envelope - SS + linear - Icosahedral
Enveloped - SS + - Icosahedral
Cryptosporidium
P. vivax/ovale

10. Parasite: Hematuria - bladder CA
bendazoles
Paramyxovirus
Schistosoma haematobium
Giardia lamblia

11. Fungal infection with rhinocerebral - frontal lobe abscesses
Coxackie A - syphilis - Rocky Mountain spotted fever
Mucor or Rhizopus spp.
No envelope
Cryptococcus neoformans

12. Severe congenital infection
Rubella
C. Difficile
Clostridium difficile - gas gangrene - double zone of hemolysis on blood agar
Ribavirin

13. Dilated cardiomyopathy - megacolon - megaesophagus
EBV
Filovirus
Mucor or Rhizopus spp.
Trypansoma cruzi. Chagas dz - S. America

14. Lassa fever encephalitis
Enveloped - SS - - circular - 2 segments - helical
Arenavirus - spread by mice
Flavivirus
Strongyloides stercoralis

15. C. tetani exotoxin: Plasmid - lysogeny - bacterial chromosome?
Plasmid
Rubeola
Coxiella burnetti
Pasteurella multocida

16. Triad of chorioretinitis - hydrocephalus - intracranial calcifications
Group A streptococcus. Helps prevent phagocytosis.
Paramyxoviruses
Sodium stibogluconate
Congenital Toxoplasma gondii

17. Tx for Taenid solium
Praziquantel
Mycoplasma pneumonia
No envelope - SS + linear - Icosahedral
EBV

18. Protozoa: Rapidly fatal meningoencephalitis
Rubella
Naegleria fowleri
Enterobius vermicularis
Rifampin

19. Transmitted by deer fly - horse fly - and mango fly; causes swelling in skin (can see worm crawling in conjunctiva)
Bartonella henselae (bacillary angiomatosis)
Mucor or Rhizopus spp.
Loa Loa
Ivermectin

20. Influenza virus
Reovirus
Toxoplasma gondii
Orthomyxovirus
Heart block - bilateral Bell's palsy

21. Reovirus
Bartonella henselae (bacillary angiomatosis)
Paragonimus westermani
Most common cause of aseptic meningitis
No envelope

22. Rhabdoviruses
Lysogeny
Cryptosporidium
P. vivax/ovale
Enveloped - SS - - linear - Helical

23. Eggs visible in feces; intestinal infection
Enveloped - SS - - circular - 2 segments - helical
Mycobacterium avium - intracellulare
Ascaris lumbricoides
Most common cause of aseptic meningitis

24. Eggs in dog feces when ingested can cause cysts in liver; causes anaphylaxis if Ags are released from cysts (surgeons inject ethanol before removal to neutralize Ags).
Heart block - bilateral Bell's palsy
Echinococcus granulosus
No envelope
Rubeola

25. Dengue fever
Loa Loa
Naegleria fowleri
Flavivirus
Amphotericin B

26. HIV - Retinitis; cotton - wool spots on funduscopic exam
Picornavirus
Giardia lamblia
Nystatin
CMV

27. 3- day rash
Rubella
Flavivirus
C. Difficile
Mucor or Rhizopus spp.

28. Foul - smelling - greenish discharge from vag; itching and burning; STD
Trichomonas vaginalis
Pseudomonas - inactivates EF-2
Necator americanus
Stains cryptococcus neoformans red

29. Eastern equine encephalitis
Deltavirus
Togavirus
Picornavirus
Reovirus

30. Tx for Lyme dz
Doxycycline - ceftriaxone
Taenid solium
Entamoeba histolytica
Trichinella spiralis

31. HIV - Interstitial pneumonia; biopsy reveals cells with intranuclear and cytoplasmic inclusion bodies
Mucor or Rhizopus spp.
Amphotericin B
Babesia
CMV

32. Tx for Loa Loa
Calicivirus
Paramyxovirus
Nifurtimox
Diethylcarbamazine

33. Rhinovirus
Diethylcarbamazine
Topical miconazole - selenium sulfide
Filovirus
Picornavirus

34. Filoviruses
Colonic epithelial cell necrosis and stimulation of fibrin deposition
P. vivax/ovale
Lysogeny
Enveloped - SS - - linear - Helical

35. Shiga toxin
Cleaves host cell rRNA (inactivates 60S ribosome); enhances cytokine release - causing HUS.
Invasive aspergillosis
Enterobius vermicularis
Trypansoma cruzi. Chagas dz - S. America

36. Flavivirus
Enveloped - SS+ - linear - icosahedral
Enveloped - SS - - linear - 8 segments - Helical
Coxackie A - syphilis - Rocky Mountain spotted fever
Deltavirus

37. HIV - Hairy leukoplakia; often on lateral tongue
Trypansoma cruzi. Chagas dz - S. America
P. falciparum
EBV
Calicivirus

38. Tx for neurocystercercosis
bendazoles
Onchocerca volvulus
Stains cryptococcus neoformans red
Cryptococcus neoformans

39. Pinworm
Enterobius vermicularis
P. vivax/ovale
Diethylcarbamazine
Picornavirus

40. Opportunistic fungal infection in ketoacidotic diabetic or leukemic patients
Mucor or Rhizopus spp.
Quinine - clindamycin
Ivermectin
Bacterial chromosome

41. RSV
Cryptococcus neoformans
Paramyxovirus
Cleaves host cell rRNA (inactivates 60S ribosome); enhances cytokine release - causing HUS.
Orthomyxovirus

42. Diphtheria toxin: Plasmid - lysogeny - bacterial chromosome?
Lysogeny
Babesia
Wuchereria bancrofti
Bunyavirus

43. dsRNA segmented virus
Aminoglycoside plus extended spectrum penicillin (piperacillin - ticarcillin)
Reovirus
CMV
Praziquantel

44. Protozoa: Severe diarrhea in AIDS - mild dz in non - immunocompromised
Lysogeny
Deltavirus
Cryptosporidium
Aminoglycoside plus extended spectrum penicillin (piperacillin - ticarcillin)

45. Rash spreads from head to toe
Taenid solium
Nifurtimox
Babesia
Rubeola

46. Fever and hemolytic anemia; predominantly in NE USA
Rubeola
T. pertenue
Reovirus
Babesia

47. Treatment for systemic infection by systemic mycoses
Amphotericin B
Doxycycline - ceftriaxone
Pathognomonic for measles or live attenuated vaccine
Wuchereria bancrofti

48. Sabouraud's agar
Cryptococcus neoformans
Palivizumab
Babesia
CMV

49. Coxackievirus
Picornavirus
Aseptic meningitis - herpangina - mycarditis
Naegleria fowleri
Ascaris lumbricoides

50. Councilman bodies (acidophilic inclusions) in liver
Amphotericin B
Arenavirus
Togavirus
Yellow fever