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Microbiology 2

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. HIV - Pneumonia CD4<200
Pneumocystis jiroveci
Schistosoma haematobium
HHV-6 (Roseola)
Rubella

2. River blindness
Schistosoma haematobium
Cryptococcus neoformans
Onchocerca volvulus
Lysogeny

3. Hepevirus
Toxoplasma gondii
Schistosoma
Bacterial chromosome
No envelope - SS + linear - Icosahedral

4. Severe; daily cycles; parasitized RBCs occlude capillaries in brain - kidneys - lungs
Metronidazole
No envelope - SS + linear - Icosahedral
Paragonimus westermani
P. falciparum

5. Food contaminated with eggs; intestinal infection; causes anal pruritis
Nonenveloped - SS + - Icosahedral
Enveloped - SS - - linear - Helical
Cryptococcus neoformans
Enterobius vermicularis

6. Tx of Schistosoma
P. vivax/ovale
Praziquantel
Rubeola
Togavirus

7. dsRNA segmented virus
HPV
Flavivirus
S. aureus. Binds Fc region of Ig. Prevents opsonization and phagocytosis.
Reovirus

8. Optochin
Echinococcus granulosus
C. Difficile
Cleaves host cell rRNA (inactivates 60S ribosome); enhances cytokine release - causing HUS.
S. pneumoniae sensitive - S. viridans resistant

9. Tx for Babesia
Trypansoma cruzi. Chagas dz - S. America
Quinine - clindamycin
Group A beta - hemolytic strep (S. pyogenes) sensitive. Group B (S. agalactiae) resistant.
Naegleria fowleri

10. Flavivirus
Bunyavirus - hemorrhagic fever - pneumonia
Enveloped - SS+ - linear - icosahedral
Group A beta - hemolytic strep (S. pyogenes) sensitive. Group B (S. agalactiae) resistant.
Orthomyxovirus

11. Arenaviruses
Strongyloides stercoralis
Paramyxovirus
Enveloped - SS - - circular - 2 segments - helical
Most common cause of aseptic meningitis

12. Protozoa: Bloating - flatulence - foul - smelling - fatty diarrhea
Clostridium difficile - gas gangrene - double zone of hemolysis on blood agar
P. falciparum
Lysogeny
Giardia lamblia

13. Yaws
Onchocerca volvulus
Toxoplasma gondii
T. pertenue
Flavivirus

14. 3- day rash
Rubella
Ascaris lumbricoides
Flavivirus
CMV

15. Bunyaviruses
Praziquantel
Enveloped - SS - - circular - 3 segments - helical
Trypanosoma (T. gambiense - T. rhodiesiense); African sleeping sickness
HPV

16. Reovirus
bendazoles
DS linear 10-12 segments
Enveloped - SS - - circular - 3 segments - helical
Enveloped - SS + - Icosahedral

17. Treatment for superficial candida infection
Amphotericin B
Nystatin
Flavivirus
P. vivax/ovale

18. HIV - Superficial neoplastic proliferation of vasculature; biopsy reveals lymphocytic inflammation
Rubeola
Cleaves IgA. S. pneumoniae - H. influenzae type B - Neisseria (SHiN) in order to colonize respiratory mucosa.
HHV-8
Echinococcus granulosus

19. Snails are host
Schistosoma
Paramyxovirus
Arenavirus - spread by mice
Orthomyxovirus

20. Giant roundworm
Strongyloides stercoralis
Ascaris lumbricoides
Togavirus
Praziquantel

21. Triad of chorioretinitis - hydrocephalus - intracranial calcifications
Enveloped - SS + - Icosahedral
Congenital Toxoplasma gondii
Paramyxovirus
Trichinella spiralis

22. Severe congenital infection
JC virus (PML) results in demyelination
Rubella
Wuchereria bancrofti
DS linear 10-12 segments

23. Reovirus
Cryptococcus neoformans
Bunyavirus
Diethylcarbamazine
Icosohedral (double)

24. Tx of Clonorchis sinensis
ADP ribosylating A- B toxin inactivates EF-2
Praziquantel
Orthomyxovirus
Rubeola

25. Parainfluenza - croup
Rifampin
JC virus (PML) results in demyelination
Paramyxovirus
Pasteurella multocida

26. M protein
Stains cryptococcus neoformans red
Pathognomonic for measles or live attenuated vaccine
Group A streptococcus. Helps prevent phagocytosis.
Clostridium difficile - gas gangrene - double zone of hemolysis on blood agar

27. Parasite: Portal hypertension
Pasteurella multocida
Paragonimus westermani
Paramyxovirus
Schistosoma mansoni

28. Western equine encephalitis
HPV
Coxackie A - syphilis - Rocky Mountain spotted fever
Togavirus
Enterobius vermicularis

29. Protozoa: Bloody diarrhea - liver abscess - RUQ pain
Stains cryptococcus neoformans red
Ivermectin
Entamoeba histolytica
No envelope

30. Undercooked crab meat; causes inflammation and secondary bacterial infection of the lung - causing hemoptysis
Schistosoma
Pasteurella multocida
Paragonimus westermani
Toxoplasma gondii

31. Prophylaxis in close contacts of pts w/Haemophilus influenzae meningitis
HHV-6 (Roseola)
Coxiella burnetti
Enveloped - SS - - linear - Helical
Rifampin

32. Deltaviruses
Enveloped - SS - - circular - helical
Enveloped - SS + - Icosahedral
Trypanosoma (T. gambiense - T. rhodiesiense); African sleeping sickness
Mycoplasma pneumonia

33. 5- day rash
Congenital Toxoplasma gondii
Pathognomonic for measles or live attenuated vaccine
Rubeola
Plasmid

34. Undercooked fish
Wuchereria bancrofti
Lysogeny
Amphotericin B
Clonorchis sinensis

35. Eggs in dog feces when ingested can cause cysts in liver; causes anaphylaxis if Ags are released from cysts (surgeons inject ethanol before removal to neutralize Ags).
Trichinella spiralis
Echinococcus granulosus
EBV
Reovirus

36. Rickettsia transmitted by aerosol; no rash - no vector - neg Weil - Felix
Calicivirus
Rubeola
No envelope - SS + linear - Icosahedral
Coxiella burnetti

37. Tx for Lyme dz
Doxycycline - ceftriaxone
P. vivax/ovale
Plasmid
Trypanosoma (T. gambiense - T. rhodiesiense); African sleeping sickness

38. Opportunistic fungal infection in ketoacidotic diabetic or leukemic patients
S. pneumoniae sensitive - S. viridans resistant
Rubella
Babesia
Mucor or Rhizopus spp.

39. In drinking water; skin inflammation and ulceration.
Nystatin
Diphyllobothrium latum
Filovirus
Dracunculus medinensis

40. HIV - Encephalopathy
S. epidermidis sensitive. S. saprophyticus resistant.
Enveloped - SS+ - linear - icosahedral
Watery diarrhea
JC virus (PML) results in demyelination

41. Rhabdoviruses
Bunyavirus - hemorrhagic fever - pneumonia
Enveloped - SS - - linear - Helical
Flavivirus
Togavirus

42. Protozoa: Rapidly fatal meningoencephalitis
Naegleria fowleri
Doxycycline - ceftriaxone
Togavirus
Rubeola

43. Parasite: Hematuria - bladder CA
Praziquantel
S. epidermidis sensitive. S. saprophyticus resistant.
Schistosoma haematobium
Invasive aspergillosis

44. HDV
Topical miconazole - selenium sulfide
Ceftriaxone
Dracunculus medinensis
Deltavirus

45. 'Soap bubble' lesion in brain
Bacterial chromosome
Cryptococcus neoformans
Onchocerca volvulus
Leishmania donovani

46. Exotoxin A
Ascaris lumbricoides
Trypansoma cruzi. Chagas dz - S. America
Enterobius vermicularis
Pseudomonas - inactivates EF-2

47. Cholangiocarcinoma
Togavirus
Invasive aspergillosis
Clonorchis sinensis
Diethylcarbamazine

48. HIV - Squamous cell carcinoma; often in anus (MSM) or cervix (females)
Echinococcus granulosus
Onchocerca volvulus
Flavivirus
HPV

49. Fungal infection with rhinocerebral - frontal lobe abscesses
Flavivirus
Wuchereria bancrofti
Giardia lamblia
Mucor or Rhizopus spp.

50. HIV - Abscesses - ring - enhancing lesions on imaging
Mycoplasma pneumonia
Toxoplasma gondii
Enveloped - SS - - circular - 2 segments - helical
Picornavirus