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Microbiology 2

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. HIV - Chronic watery diarrhea; acid - fast cysts seen in stool
C. Difficile
Cryptosporidium spp.
Diphyllobothrium latum
Reovirus

2. Periorbital edema
Pneumocystis jiroveci
Enveloped - SS - - circular - 2 segments - helical
Trichinella spiralis
Onchocerca volvulus

3. C. tetani exotoxin: Plasmid - lysogeny - bacterial chromosome?
Lysogeny
Babesia
Plasmid
Clostridium difficile - gas gangrene - double zone of hemolysis on blood agar

4. IgA protease
Rubeola
Coxiella burnetti
Enveloped - SS - - circular - 3 segments - helical
Cleaves IgA. S. pneumoniae - H. influenzae type B - Neisseria (SHiN) in order to colonize respiratory mucosa.

5. Mucicarmine
Togavirus
Stains cryptococcus neoformans red
Trichinella spiralis
Yellow fever

6. Rash spreads from head to toe
Congenital Toxoplasma gondii
Retrovirus
Rubeola
Rifampin

7. Paramyxoviruses
Enveloped - SS - - linear - nonsegmented - Helical
Mycoplasma pneumonia
Congenital rubella
Clonorchis sinensis

8. Rubella
Lysogeny
Praziquantel
Togavirus
Aminoglycoside plus extended spectrum penicillin (piperacillin - ticarcillin)

9. Mumps
Paramyxovirus
Icosohedral (double)
Lysogeny
ADP ribosylating A- B toxin inactivates EF-2

10. California encephalitis
bendazoles
Lysogeny
Bunyavirus
Praziquantel

11. Protozoa: Rapidly fatal meningoencephalitis
Enveloped - SS + - Icosahedral
Paramyxovirus
Diethylcarbamazine
Naegleria fowleri

12. HIV - Hairy leukoplakia; often on lateral tongue
Filovirus
Ancylostoma duodenale - Necator americanus
Stains cryptococcus neoformans red
EBV

13. Tx for Loa Loa
Loa Loa
Schistosoma
P. falciparum
Diethylcarbamazine

14. Arenaviruses
Togavirus
Enveloped - SS - - circular - 2 segments - helical
Enveloped - SS+ - linear - icosahedral
Togavirus

15. 'swiss cheese' appearance in brain
Arenavirus - spread by mice
Echinococcus granulosus
Taenid solium
Cryptococcus neoformans

16. Tx for Babesia
Quinine - clindamycin
Trypanosoma (T. gambiense - T. rhodiesiense); African sleeping sickness
Bartonella henselae (bacillary angiomatosis)
Group A beta - hemolytic strep (S. pyogenes) sensitive. Group B (S. agalactiae) resistant.

17. Severe congenital infection
Onchocerca volvulus
Paramyxoviruses
Rubella
Picornavirus

18. West nile virus
Naegleria fowleri
Flavivirus
Paramyxovirus
Trichinella spiralis

19. HIV - Abscesses - ring - enhancing lesions on imaging
Toxoplasma gondii
S. aureus. Binds Fc region of Ig. Prevents opsonization and phagocytosis.
Praziquantel
Diethylcarbamazine

20. Hepevirus
No envelope - SS + linear - Icosahedral
Coxiella burnetti
Rubella
Echinococcus granulosus

21. Cycles occuring every other day; dormant form in liver -> tx w/primaquine
Group A streptococcus. Helps prevent phagocytosis.
Pneumocystis jiroveci
P. vivax/ovale
Yellow fever

22. Rash preceded by cough - coryza - conjunctivitis
Paramyxovirus
Rubeola
Enveloped - SS+ - linear - icosahedral
Heart block - bilateral Bell's palsy

23. Triad of chorioretinitis - hydrocephalus - intracranial calcifications
Enterobius vermicularis
Diethylcarbamazine
Clostridium difficile - gas gangrene - double zone of hemolysis on blood agar
Congenital Toxoplasma gondii

24. Inflammation of muscle (larvae encyst in muscle)
Trichinella spiralis
Cryptosporidium spp.
Bunyavirus - hemorrhagic fever - pneumonia
Picornavirus

25. Cytotoxin B
Reovirus
Ceftriaxone
Colonic epithelial cell necrosis and stimulation of fibrin deposition
Diethylcarbamazine

26. Dengue fever
Babesia
Mycobacterium avium - intracellulare
Flavivirus
Diethylcarbamazine

27. Echovirus
Mycoplasma pneumonia
Ceftriaxone
Most common cause of aseptic meningitis
Congenital Toxoplasma gondii

28. Severe; daily cycles; parasitized RBCs occlude capillaries in brain - kidneys - lungs
Quinine - clindamycin
Icosohedral (double)
Clonorchis sinensis
P. falciparum

29. HDV
ADP ribosylating A- B toxin inactivates EF-2
No envelope - SS + linear - Icosahedral
Cleaves IgA. S. pneumoniae - H. influenzae type B - Neisseria (SHiN) in order to colonize respiratory mucosa.
Deltavirus

30. Crimean - Congo hemorrhagic fever
Bunyavirus
Paramyxovirus
Ancylostoma - Necator
Rubella

31. Causes inflammation of the biliary tract -> pigmented gallstones
Clonorchis sinensis
Plasmid
Stains cryptococcus neoformans red
Yellow fever

32. Fever then rash
Rubella
Paramyxovirus
HHV-6 (Roseola)
S. aureus. Binds Fc region of Ig. Prevents opsonization and phagocytosis.

33. Exotoxin A
Enterobius vermicularis
Pseudomonas - inactivates EF-2
Calicivirus
CMV

34. Tx for Pseudomonas aeruginosa
Cryptosporidium spp.
Rubella
Aminoglycoside plus extended spectrum penicillin (piperacillin - ticarcillin)
Congenital rubella

35. 'Soap bubble' lesion in brain
Cryptococcus neoformans
T. pertenue
Necator americanus
S. epidermidis sensitive. S. saprophyticus resistant.

36. Bacitracin
Group A beta - hemolytic strep (S. pyogenes) sensitive. Group B (S. agalactiae) resistant.
Trichinella spiralis
Clostridium difficile - gas gangrene - double zone of hemolysis on blood agar
Strongyloides stercoralis

37. Tx for neurocystercercosis
HPV
Topical miconazole - selenium sulfide
C. Difficile
bendazoles

38. Parasite: Liver cysts
Paramyxoviruses
Nystatin
Togavirus
Echinococcus granulosus

39. Colorado tick fever
Bunyavirus - hemorrhagic fever - pneumonia
Ribavirin
Reovirus
Coxiella burnetti

40. HIV - TB like dz CD4<50
Enveloped - SS - - linear - Helical
EBV
Diethylcarbamazine
Mycobacterium avium - intracellulare

41. Enlarged lymph nodes - recurring fever (d/t Ag variation) - somnolence - coma
Trypanosoma (T. gambiense - T. rhodiesiense); African sleeping sickness
Stains cryptococcus neoformans red
Rubeola
Watery diarrhea

42. Diphtheria toxin: Plasmid - lysogeny - bacterial chromosome?
Lysogeny
Pasteurella multocida
Rubeola
Cryptococcus neoformans

43. Eastern equine encephalitis
Lysogeny
Togavirus
Yellow fever
Leishmania donovani

44. HIV - Encephalopathy
Congenital rubella
P. vivax/ovale
Arenavirus - spread by mice
JC virus (PML) results in demyelination

45. Tx for RSV
Enveloped - SS - - linear - Helical
Ribavirin
Picornavirus
Mycoplasma pneumonia

46. Tx of Paragonimus westermani
Rubella
Yellow fever
CMV
Praziquantel

47. RSV
ADP ribosylating A- B toxin inactivates EF-2
Congenital rubella
Paramyxovirus
Onchocerca volvulus

48. Tx for Leishmania donovani
Pseudomonas - inactivates EF-2
ADP ribosylating A- B toxin inactivates EF-2
Sodium stibogluconate
Lysogeny

49. Pinworm
EBV
Flavivirus
Enterobius vermicularis
Reovirus

50. Female mosquito; causes blockage of lymphatic vessels (elephantitis). Takes 9 months to 1 year after bite to get elephantiasis sx.
Wuchereria bancrofti
Schistosoma mansoni
Enveloped - SS - - circular - 2 segments - helical
Pathognomonic for measles or live attenuated vaccine