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Microbiology 2

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. M protein
Palivizumab
Cleaves IgA. S. pneumoniae - H. influenzae type B - Neisseria (SHiN) in order to colonize respiratory mucosa.
Group A streptococcus. Helps prevent phagocytosis.
Paramyxovirus

2. Protozoa: Bloody diarrhea - liver abscess - RUQ pain
Entamoeba histolytica
Clostridium difficile - gas gangrene - double zone of hemolysis on blood agar
Topical miconazole - selenium sulfide
Schistosoma haematobium

3. Togavirus
Necator americanus
ADP ribosylating A- B toxin inactivates EF-2
EBV
Enveloped - SS+ - linear - icosahedral

4. HIV - Squamous cell carcinoma; often in anus (MSM) or cervix (females)
P. falciparum
Togavirus
HPV
Icosohedral (double)

5. River blindness
Onchocerca volvulus
Schistosoma
Pasteurella multocida
Rubeola

6. Ebola/Marburg hemorrhagic fever
Erythromycin
Picornavirus
Filovirus
Amphotericin B

7. Novobiocin
Rubella
Rubeola
S. epidermidis sensitive. S. saprophyticus resistant.
Rubella

8. Enlarged lymph nodes - recurring fever (d/t Ag variation) - somnolence - coma
EBV
Toxocara canis
EBV
Trypanosoma (T. gambiense - T. rhodiesiense); African sleeping sickness

9. HIV - TB like dz CD4<50
Lysogeny
Togavirus
Invasive aspergillosis
Mycobacterium avium - intracellulare

10. Used in RSV to neutralize F protein
P. vivax/ovale
Palivizumab
C. Difficile
Nifurtimox

11. 5- day rash
HPV
Trichinella spiralis
Pathognomonic for measles or live attenuated vaccine
Rubeola

12. Tx for Leishmania donovani
Ancylostoma - Necator
Sodium stibogluconate
Cryptococcus neoformans
bendazoles

13. Tx for Wuchereria bancrofti
C. Difficile
Diethylcarbamazine
Clostridium difficile - gas gangrene - double zone of hemolysis on blood agar
No envelope - SS + linear - Icosahedral

14. High fever - black vomitus - jaundice
Diethylcarbamazine
Group A streptococcus. Helps prevent phagocytosis.
Yellow fever
Enveloped - SS+ - linear - icosahedral

15. Periorbital edema
Clonorchis sinensis
Trichinella spiralis
Calicivirus
Necator americanus

16. Tx for Echinococcus granulosus
bendazoles
Yellow fever
Deltavirus
Diphyllobothrium latum

17. dsRNA segmented virus
Plasmid
Giardia lamblia
Reovirus
Enveloped - SS - - circular - 2 segments - helical

18. Rotavirus
Paramyxoviruses
Enveloped - SS - - linear - Helical
Reovirus
Trypansoma cruzi. Chagas dz - S. America

19. Eggs visible in feces; intestinal infection
Clonorchis sinensis
Congenital rubella
Nonenveloped - SS + - Icosahedral
Ascaris lumbricoides

20. Norwalk virus - viral gastroenteritis
Calicivirus
Watery diarrhea
Togavirus
Nystatin

21. Parainfluenza - croup
Paramyxovirus
Pneumocystis jiroveci
Filovirus
Trichinella spiralis

22. Poliovirus
Picornavirus
Amphotericin B
C. Difficile
Sodium stibogluconate

23. Pinworm
Enterobius vermicularis
Coxackie A - syphilis - Rocky Mountain spotted fever
Clonorchis sinensis
Aminoglycoside plus extended spectrum penicillin (piperacillin - ticarcillin)

24. Echovirus
Mucor or Rhizopus spp.
Trichinella spiralis
Praziquantel
Picornavirus

25. IgA protease
Lysogeny
Schistosoma
Cleaves IgA. S. pneumoniae - H. influenzae type B - Neisseria (SHiN) in order to colonize respiratory mucosa.
Enveloped - SS - - linear - 8 segments - Helical

26. Shuffner dots
Naegleria fowleri
P. vivax/ovale
Giardia lamblia
Picornavirus

27. Eggs in dog feces when ingested can cause cysts in liver; causes anaphylaxis if Ags are released from cysts (surgeons inject ethanol before removal to neutralize Ags).
Mycobacterium avium - intracellulare
Picornavirus
Echinococcus granulosus
Aminoglycoside plus extended spectrum penicillin (piperacillin - ticarcillin)

28. Fever then rash
HHV-6 (Roseola)
Cryptosporidium spp.
Enveloped - SS + - Icosahedral
Congenital Toxoplasma gondii

29. Treatment for superficial candida infection
Nystatin
Strongyloides stercoralis
Arenavirus - spread by mice
Paramyxovirus

30. Opportunistic fungal infection in ketoacidotic diabetic or leukemic patients
Invasive aspergillosis
Mycobacterium avium - intracellulare
Togavirus
Mucor or Rhizopus spp.

31. Transmitted by female blackflies; causes hyperpigmented skin. Can have allergic reaction to microfilaria
Trypansoma cruzi. Chagas dz - S. America
Onchocerca volvulus
Paramyxovirus
Bunyavirus

32. Foul - smelling - greenish discharge from vag; itching and burning; STD
Onchocerca volvulus
Clostridium difficile - gas gangrene - double zone of hemolysis on blood agar
Rubeola
Trichomonas vaginalis

33. Protozoa: Bloating - flatulence - foul - smelling - fatty diarrhea
C. Difficile
Plasmid
Picornavirus
Giardia lamblia

34. Ingestion of larvae encysted in undercooked pork. Cysticercosis and neurocysticercosis - mass lesions in brain.
Taenid solium
HHV-8
Topical miconazole - selenium sulfide
Toxocara canis

35. Parasite: Liver cysts
C. Difficile
Congenital Toxoplasma gondii
Enveloped - SS + - Icosahedral
Echinococcus granulosus

36. Retroviruses
Lysogeny
Enveloped - SS - - linear - Helical
Enveloped - SS + - Icosahedral
bendazoles

37. Larvae penetrateskin of feet; intestinal infection can cause anemia (suck blood from intestinal walls).
CMV
Ancylostoma duodenale - Necator americanus
Picornavirus
Bacterial chromosome

38. Tx of Clonorchis sinensis
Toxoplasma gondii
Echinococcus granulosus
Paramyxovirus
Praziquantel

39. HIV - Abscesses - ring - enhancing lesions on imaging
Necator americanus
Stains cryptococcus neoformans red
Toxoplasma gondii
Enveloped - SS + - Icosahedral

40. HIV - Retinitis; cotton - wool spots on funduscopic exam
Leishmania donovani
CMV
Yellow fever
Diphyllobothrium latum

41. Tx of Schistosoma
Pseudomonas - inactivates EF-2
Strongyloides stercoralis
Fluconazole or ketoconazole
Praziquantel

42. Food contaminated with eggs; intestinal infection; causes anal pruritis
Lysogeny
Enterobius vermicularis
Clonorchis sinensis
Cryptosporidium spp.

43. Western equine encephalitis
Group A streptococcus. Helps prevent phagocytosis.
Togavirus
Praziquantel
Ancylostoma duodenale - Necator americanus

44. Protein A
Cryptococcus neoformans
C. Difficile
Strongyloides stercoralis
S. aureus. Binds Fc region of Ig. Prevents opsonization and phagocytosis.

45. HAV
Pneumocystis jiroveci
Rubeola
Enterobius vermicularis
Picornavirus

46. 3- day rash
HHV-8
Ascaris lumbricoides
Bunyavirus
Rubella

47. HIV - Superficial vascular proliferation; biopsy reveals neutrophilic inflammation
Topical miconazole - selenium sulfide
No envelope - SS + linear - Icosahedral
Bartonella henselae (bacillary angiomatosis)
Coxackie A - syphilis - Rocky Mountain spotted fever

48. Diphtheria toxin: Plasmid - lysogeny - bacterial chromosome?
Lysogeny
Schistosoma
Enveloped - SS + - Icosahedral
Plasmid

49. Enterotoxin A
Metronidazole
Watery diarrhea
Invasive aspergillosis
Erythromycin

50. Inflammation of muscle (larvae encyst in muscle)
Doxycycline - ceftriaxone
Trichinella spiralis
Icosohedral (double)
Yellow fever