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Microbiology 2

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Enlarged lymph nodes - recurring fever (d/t Ag variation) - somnolence - coma
Trypanosoma (T. gambiense - T. rhodiesiense); African sleeping sickness
Enveloped - SS+ - linear - icosahedral
Rifampin
Enterobius vermicularis

2. Subacute sclerosing panencephalitis
Bunyavirus - hemorrhagic fever - pneumonia
Nystatin
Cryptococcus neoformans
Rubeola

3. Generalized lymphadenopathy particularly postauricular and occipital
Loa Loa
ADP ribosylating A- B toxin inactivates EF-2
Reovirus
Rubella

4. Treatment for Tinea versicolor
Lysogeny
Flavivirus
Arenavirus
Topical miconazole - selenium sulfide

5. C. tetani exotoxin: Plasmid - lysogeny - bacterial chromosome?
HHV-8
Colonic epithelial cell necrosis and stimulation of fibrin deposition
Plasmid
Group A beta - hemolytic strep (S. pyogenes) sensitive. Group B (S. agalactiae) resistant.

6. LCMV - lymphocytic choriomeningitis virus
Togavirus
DS linear 10-12 segments
Togavirus
Arenavirus

7. Cellulitis from animal bite
Paramyxovirus
Erythromycin
Pasteurella multocida
Praziquantel

8. Yellow fever
Entamoeba histolytica
Schistosoma
Enterobius vermicularis
Flavivirus

9. Triad of chorioretinitis - hydrocephalus - intracranial calcifications
Bunyavirus
Congenital Toxoplasma gondii
Praziquantel
Trypansoma cruzi. Chagas dz - S. America

10. Bunyaviruses
Togavirus
Enveloped - SS - - circular - 3 segments - helical
Pseudomonas - inactivates EF-2
Praziquantel

11. 'swiss cheese' appearance in brain
DS linear 10-12 segments
No envelope - SS + linear - Icosahedral
Taenid solium
Giardia lamblia

12. Treatment for Sporothrix schenckii
Itraconazole or potassium iodide
Yellow fever
Cryptosporidium
Nifurtimox

13. HIV - Superficial neoplastic proliferation of vasculature; biopsy reveals lymphocytic inflammation
HHV-8
Enveloped - SS - - linear - Helical
Flavivirus
Heart block - bilateral Bell's palsy

14. Protozoa: Brain abscess in HIV
CMV
Flavivirus
Toxoplasma gondii
Ribavirin

15. dsRNA segmented virus
bendazoles
Leishmania donovani
Reovirus
Ancylostoma - Necator

16. Treatment for superficial candida infection
Colonic epithelial cell necrosis and stimulation of fibrin deposition
Stains cryptococcus neoformans red
Sodium stibogluconate
Nystatin

17. HIV - Superficial vascular proliferation; biopsy reveals neutrophilic inflammation
HHV-6 (Roseola)
Bartonella henselae (bacillary angiomatosis)
Enveloped - SS - - linear - nonsegmented - Helical
Yellow fever

18. Eastern equine encephalitis
Echinococcus granulosus
P. vivax/ovale
Togavirus
CMV

19. HIV - Chronic watery diarrhea; acid - fast cysts seen in stool
Schistosoma
Metronidazole
Enveloped - SS - - circular - 3 segments - helical
Cryptosporidium spp.

20. M protein
Coxiella burnetti
Group A streptococcus. Helps prevent phagocytosis.
Dracunculus medinensis
S. pneumoniae sensitive - S. viridans resistant

21. Arenaviruses
Congenital rubella
Nystatin
Coxackie A - syphilis - Rocky Mountain spotted fever
Enveloped - SS - - circular - 2 segments - helical

22. Cercariae penetrate skin of humans; causes granulomas - fibrosis - and inflammation of the spleen and liver. Chronic infection can lead to squamous cell carcinoma of the bladder.
Bunyavirus
Onchocerca volvulus
Schistosoma
Enveloped - SS - - linear - nonsegmented - Helical

23. Reovirus
Paramyxovirus
DS linear 10-12 segments
CMV
Metronidazole

24. Coxackievirus
Quinine - clindamycin
Aseptic meningitis - herpangina - mycarditis
Flavivirus
Naegleria fowleri

25. HIV - Encephalopathy
JC virus (PML) results in demyelination
Coxiella burnetti
Giardia lamblia
Cleaves host cell rRNA (inactivates 60S ribosome); enhances cytokine release - causing HUS.

26. Coronaviruses
Praziquantel
Enveloped - SS + - Icosahedral
P. vivax/ovale
Icosohedral (double)

27. Calicivirus
Orthomyxovirus
Rifampin
No envelope - SS + linear - Icosahedral
Reovirus

28. Coxackievirus
Picornavirus
Rifampin
Rubeola
Diphyllobothrium latum

29. Hepevirus
No envelope - SS + linear - Icosahedral
Necator americanus
Mucor or Rhizopus spp.
Ascaris lumbricoides

30. Reovirus
Trichomonas vaginalis
Arenavirus - spread by mice
No envelope
S. aureus. Binds Fc region of Ig. Prevents opsonization and phagocytosis.

31. Tx of Schistosoma
Praziquantel
Rubeola
Deltavirus
Arenavirus - spread by mice

32. Erythrogenic exotoxin of strep pyogenes: Plasmid - lysogeny - bacterial chromosome?
Picornavirus
Coxackie A - syphilis - Rocky Mountain spotted fever
Lysogeny
Bacterial chromosome

33. Tx for Trichomonas vaginalis
Ribavirin
Paramyxovirus
Metronidazole
Ivermectin

34. 5- day rash
Heart block - bilateral Bell's palsy
Most common cause of aseptic meningitis
Cryptosporidium
Rubeola

35. Tx for Pseudomonas aeruginosa
Paramyxovirus
Aminoglycoside plus extended spectrum penicillin (piperacillin - ticarcillin)
Calicivirus
Lysogeny

36. Tx for Toxocara canis
S. pneumoniae sensitive - S. viridans resistant
Enveloped - SS - - circular - 2 segments - helical
Schistosoma
Diethylcarbamazine

37. River blindness
Lysogeny
P. vivax/ovale
Onchocerca volvulus
Togavirus

38. Reovirus
Icosohedral (double)
Paramyxovirus
Taenid solium
Toxocara canis

39. Ingestion of larvae encysted in undercooked pork. Cysticercosis and neurocysticercosis - mass lesions in brain.
Enveloped - SS - - linear - 8 segments - Helical
Taenid solium
P. vivax/ovale
Enveloped - SS+ - linear - icosahedral

40. Parasite: Hematuria - bladder CA
Schistosoma
HPV
Rubella
Schistosoma haematobium

41. Parasite: Portal hypertension
Deltavirus
Trichomonas vaginalis
Schistosoma mansoni
Stains cryptococcus neoformans red

42. Echovirus
Doxycycline - ceftriaxone
Picornavirus
Enveloped - SS - - linear - 8 segments - Helical
Group A streptococcus. Helps prevent phagocytosis.

43. Norwalk virus - viral gastroenteritis
No envelope - SS + linear - Icosahedral
Mycoplasma pneumonia
Calicivirus
Pathognomonic for measles or live attenuated vaccine

44. Cytotoxin B
Colonic epithelial cell necrosis and stimulation of fibrin deposition
Loa Loa
bendazoles
Watery diarrhea

45. Togavirus
S. pneumoniae sensitive - S. viridans resistant
Flavivirus
Enveloped - SS+ - linear - icosahedral
Bunyavirus

46. Undercooked fish
Clonorchis sinensis
Amphotericin B
Enveloped - SS+ - linear - icosahedral
Wuchereria bancrofti

47. 3- day rash
Mycoplasma pneumonia
Quinine - clindamycin
Toxoplasma gondii
Rubella

48. Kala - azar: spiking fevers - hepatosplenomegaly - pancytopenia
Heart block - bilateral Bell's palsy
Quinine - clindamycin
Leishmania donovani
Colonic epithelial cell necrosis and stimulation of fibrin deposition

49. Periorbital edema
Trichinella spiralis
Enterobius vermicularis
CMV
Ivermectin

50. HIV - Meningitis; India ink stain reveals narrow - based budding
Naegleria fowleri
Cryptococcus neoformans
P. vivax/ovale
bendazoles