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Microbiology 2

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Fungal infection with rhinocerebral - frontal lobe abscesses
Togavirus
Mucor or Rhizopus spp.
Bacterial chromosome
HHV-6 (Roseola)

2. Severe; daily cycles; parasitized RBCs occlude capillaries in brain - kidneys - lungs
Trichinella spiralis
Taenid solium
P. falciparum
Mucor or Rhizopus spp.

3. Reovirus
Reovirus
Enveloped - SS - - linear - Helical
No envelope
Clonorchis sinensis

4. Protozoa: Brain abscess in HIV
Toxoplasma gondii
Itraconazole or potassium iodide
Cryptococcus neoformans
Trypanosoma (T. gambiense - T. rhodiesiense); African sleeping sickness

5. Parasite: Liver cysts
Enveloped - SS - - linear - nonsegmented - Helical
Pseudomonas - inactivates EF-2
Taenid solium
Echinococcus granulosus

6. Influenza virus
Orthomyxovirus
Nifurtimox
Enveloped - SS - - linear - Helical
EBV

7. Bacitracin
Paramyxoviruses
Erythromycin
Group A beta - hemolytic strep (S. pyogenes) sensitive. Group B (S. agalactiae) resistant.
No envelope - SS + linear - Icosahedral

8. River blindness
Flavivirus
Onchocerca volvulus
T. pertenue
Paragonimus westermani

9. HIV - Pneumonia CD4<200
Flavivirus
Colonic epithelial cell necrosis and stimulation of fibrin deposition
S. epidermidis sensitive. S. saprophyticus resistant.
Pneumocystis jiroveci

10. Novobiocin
Pathognomonic for measles or live attenuated vaccine
Picornavirus
Orthomyxovirus
S. epidermidis sensitive. S. saprophyticus resistant.

11. Food contaminated with eggs; intestinal infection; causes anal pruritis
Rubella
Enterobius vermicularis
Arenavirus
Mucor or Rhizopus spp.

12. Used in RSV to neutralize F protein
T. pertenue
Palivizumab
Picornavirus
Flavivirus

13. Fever and hemolytic anemia; predominantly in NE USA
Giardia lamblia
Babesia
Bunyavirus
C. Difficile

14. Western equine encephalitis
Togavirus
Enveloped - SS + - Icosahedral
No envelope - SS + linear - Icosahedral
Cleaves host cell rRNA (inactivates 60S ribosome); enhances cytokine release - causing HUS.

15. Tx for RSV
Ribavirin
Wuchereria bancrofti
Schistosoma haematobium
Ascaris lumbricoides

16. Protozoa: Bloating - flatulence - foul - smelling - fatty diarrhea
Giardia lamblia
Praziquantel
Enveloped - SS - - linear - Helical
C. Difficile

17. Yaws
Picornavirus
Leishmania donovani
T. pertenue
Arenavirus

18. Cholangiocarcinoma
Cryptococcus neoformans
Clonorchis sinensis
Ribavirin
T. pertenue

19. 5- day rash
Congenital rubella
Flavivirus
Fluconazole or ketoconazole
Rubeola

20. High fever - black vomitus - jaundice
Yellow fever
Colonic epithelial cell necrosis and stimulation of fibrin deposition
Orthomyxovirus
JC virus (PML) results in demyelination

21. HIV - TB like dz CD4<50
Mycobacterium avium - intracellulare
Aminoglycoside plus extended spectrum penicillin (piperacillin - ticarcillin)
Lysogeny
Group A streptococcus. Helps prevent phagocytosis.

22. Corynebacterium diptheria toxin
Mucor or Rhizopus spp.
Invasive aspergillosis
Enveloped - SS - - linear - nonsegmented - Helical
ADP ribosylating A- B toxin inactivates EF-2

23. Ocular problems (cataracts - retinopathy - micropthalmos - glaucoma) - cardiovascular problems (PDA - VSD - pulmonary stenosis) - deafness - thrombocytopenia purpura - hepatosplenomegaly - CNS problems - bony lesions
No envelope
T. pertenue
Congenital rubella
Togavirus

24. IgA protease
Filovirus
Yellow fever
Cleaves IgA. S. pneumoniae - H. influenzae type B - Neisseria (SHiN) in order to colonize respiratory mucosa.
Toxoplasma gondii

25. Rubeola
Paramyxovirus
Nystatin
Onchocerca volvulus
Enterobius vermicularis

26. Filoviruses
P. vivax/ovale
Enveloped - SS - - linear - Helical
Congenital rubella
DS linear 10-12 segments

27. Opportunistic fungal infection in ketoacidotic diabetic or leukemic patients
Bacterial chromosome
Mucor or Rhizopus spp.
Calicivirus
Schistosoma mansoni

28. Prophylaxis in close contacts of pts w/Haemophilus influenzae meningitis
Onchocerca volvulus
Taenid solium
Rubella
Rifampin

29. Tx of Paragonimus westermani
Picornavirus
Praziquantel
Wuchereria bancrofti
Togavirus

30. Sandfly/Rift valley fevers
Calicivirus
Bunyavirus
Picornavirus
Trichinella spiralis

31. Alpha toxin
Congenital rubella
Reovirus
Picornavirus
Clostridium difficile - gas gangrene - double zone of hemolysis on blood agar

32. HCV
Reovirus
Rubeola
Echinococcus granulosus
Flavivirus

33. Mucicarmine
Enveloped - SS - - circular - 3 segments - helical
Stains cryptococcus neoformans red
Ascaris lumbricoides
Lysogeny

34. Cytotoxin B
C. Difficile
Cleaves IgA. S. pneumoniae - H. influenzae type B - Neisseria (SHiN) in order to colonize respiratory mucosa.
Nifurtimox
Bunyavirus - hemorrhagic fever - pneumonia

35. Eaton's agar
Mycoplasma pneumonia
Rubella
Aminoglycoside plus extended spectrum penicillin (piperacillin - ticarcillin)
Leishmania donovani

36. Tx for Pseudomonas aeruginosa
Aminoglycoside plus extended spectrum penicillin (piperacillin - ticarcillin)
Most common cause of aseptic meningitis
Bunyavirus
Calicivirus

37. Parasite: Microcytic anemia
Arenavirus
Reovirus
Ancylostoma - Necator
Rubella

38. Pinworm
Reovirus
Togavirus
Trichinella spiralis
Enterobius vermicularis

39. HIV - Non - hodgkin's lymphoma (large cell type); often on oropharynx (Waldeyer's ring)
DS linear 10-12 segments
Praziquantel
EBV
Togavirus

40. HIV - Superficial vascular proliferation; biopsy reveals neutrophilic inflammation
Bartonella henselae (bacillary angiomatosis)
Picornavirus
C. Difficile
Babesia

41. Reovirus
Togavirus
No envelope - SS + linear - Icosahedral
Icosohedral (double)
Diethylcarbamazine

42. Cercariae penetrate skin of humans; causes granulomas - fibrosis - and inflammation of the spleen and liver. Chronic infection can lead to squamous cell carcinoma of the bladder.
Schistosoma
P. falciparum
Nonenveloped - SS + - Icosahedral
Rifampin

43. Cytotoxin B
Picornavirus
Colonic epithelial cell necrosis and stimulation of fibrin deposition
Reovirus
Pneumocystis jiroveci

44. Tx for Toxocara canis
Diethylcarbamazine
Sodium stibogluconate
Flavivirus
C. Difficile

45. Yellow fever
Icosohedral (double)
Flavivirus
Rubeola
Paramyxoviruses

46. HDV
Deltavirus
Picornavirus
No envelope - SS + linear - Icosahedral
Mycoplasma pneumonia

47. M protein
Trichomonas vaginalis
Group A streptococcus. Helps prevent phagocytosis.
Paragonimus westermani
Enveloped - SS - - circular - helical

48. Tx for Wuchereria bancrofti
Diethylcarbamazine
Sodium stibogluconate
Enveloped - SS+ - linear - icosahedral
Babesia

49. Shiga toxin: Plasmid - lysogeny - bacterial chromosome?
Toxoplasma gondii
Bacterial chromosome
Giardia lamblia
Toxocara canis

50. Reovirus
Rubella
DS linear 10-12 segments
Bartonella henselae (bacillary angiomatosis)
Strongyloides stercoralis