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Microbiology 2

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Reovirus
Icosohedral (double)
ADP ribosylating A- B toxin inactivates EF-2
Enveloped - SS - - linear - Helical
Dracunculus medinensis

2. Bacitracin
Reovirus
Group A beta - hemolytic strep (S. pyogenes) sensitive. Group B (S. agalactiae) resistant.
Lysogeny
Togavirus

3. Tx for Echinococcus granulosus
bendazoles
Babesia
Invasive aspergillosis
Ceftriaxone

4. Shiga toxin
P. falciparum
No envelope - SS + linear - Icosahedral
Orthomyxovirus
Cleaves host cell rRNA (inactivates 60S ribosome); enhances cytokine release - causing HUS.

5. HIV - Superficial neoplastic proliferation of vasculature; biopsy reveals lymphocytic inflammation
Amphotericin B
Aminoglycoside plus extended spectrum penicillin (piperacillin - ticarcillin)
Group A beta - hemolytic strep (S. pyogenes) sensitive. Group B (S. agalactiae) resistant.
HHV-8

6. Coxackievirus
Dracunculus medinensis
Leishmania donovani
Congenital Toxoplasma gondii
Aseptic meningitis - herpangina - mycarditis

7. Pinworm
Enterobius vermicularis
Plasmid
Schistosoma
Mycoplasma pneumonia

8. High fever - black vomitus - jaundice
Praziquantel
Rubella
Rubeola
Yellow fever

9. Tx for Wuchereria bancrofti
Diethylcarbamazine
Picornavirus
Group A beta - hemolytic strep (S. pyogenes) sensitive. Group B (S. agalactiae) resistant.
Toxocara canis

10. HIV - Pneumonia CD4<200
Rubeola
Cleaves IgA. S. pneumoniae - H. influenzae type B - Neisseria (SHiN) in order to colonize respiratory mucosa.
Pneumocystis jiroveci
Aminoglycoside plus extended spectrum penicillin (piperacillin - ticarcillin)

11. Tx for Legionella pneumophila
Erythromycin
Yellow fever
JC virus (PML) results in demyelination
Group A streptococcus. Helps prevent phagocytosis.

12. Hepevirus
Togavirus
Trypansoma cruzi. Chagas dz - S. America
Filovirus
No envelope - SS + linear - Icosahedral

13. Lyme disease

14. Protozoa: Severe diarrhea in AIDS - mild dz in non - immunocompromised
Cryptosporidium
Schistosoma
Flavivirus
Diethylcarbamazine

15. Bunyaviruses
Picornavirus
P. falciparum
Pseudomonas - inactivates EF-2
Enveloped - SS - - circular - 3 segments - helical

16. Eastern equine encephalitis
T. pertenue
Yellow fever
Togavirus
Rubella

17. Rhabdoviruses
Echinococcus granulosus
P. vivax/ovale
Schistosoma mansoni
Enveloped - SS - - linear - Helical

18. Treatment for Haemophilus influenzae meningitis
Paramyxovirus
Flavivirus
Palivizumab
Ceftriaxone

19. Rash spreads from head to toe
Schistosoma mansoni
Rubeola
Reovirus
Ceftriaxone

20. Tx for Leishmania donovani
Sodium stibogluconate
Fluconazole or ketoconazole
Nystatin
Colonic epithelial cell necrosis and stimulation of fibrin deposition

21. Tx for Trichomonas vaginalis
Diethylcarbamazine
Enterobius vermicularis
Metronidazole
Enveloped - SS + - Icosahedral

22. Kala - azar: spiking fevers - hepatosplenomegaly - pancytopenia
Cleaves IgA. S. pneumoniae - H. influenzae type B - Neisseria (SHiN) in order to colonize respiratory mucosa.
bendazoles
Trichinella spiralis
Leishmania donovani

23. Reovirus
DS linear 10-12 segments
Taenid solium
Paramyxoviruses
Ancylostoma duodenale - Necator americanus

24. Tx for Taenid solium
JC virus (PML) results in demyelination
Praziquantel
Heart block - bilateral Bell's palsy
bendazoles

25. Cellulitis from animal bite
Mucor or Rhizopus spp.
Cryptosporidium
Pasteurella multocida
Colonic epithelial cell necrosis and stimulation of fibrin deposition

26. Shiga toxin: Plasmid - lysogeny - bacterial chromosome?
Amphotericin B
Bacterial chromosome
Enterobius vermicularis
Togavirus

27. Snails are host
Congenital rubella
Schistosoma
Lysogeny
Mucor or Rhizopus spp.

28. Exotoxin A
Pseudomonas - inactivates EF-2
Trypanosoma (T. gambiense - T. rhodiesiense); African sleeping sickness
Topical miconazole - selenium sulfide
Enterobius vermicularis

29. HTLV
Enveloped - SS - - linear - Helical
Retrovirus
Invasive aspergillosis
Bunyavirus

30. Reovirus
No envelope
Enveloped - SS+ - linear - icosahedral
Schistosoma
Togavirus

31. HIV - Interstitial pneumonia; biopsy reveals cells with intranuclear and cytoplasmic inclusion bodies
Enveloped - SS+ - linear - icosahedral
CMV
Trichomonas vaginalis
Rubeola

32. Tx for Babesia
No envelope - SS + linear - Icosahedral
Echinococcus granulosus
Quinine - clindamycin
Diethylcarbamazine

33. Rubella
Rubella
Togavirus
Colonic epithelial cell necrosis and stimulation of fibrin deposition
Enveloped - SS - - linear - Helical

34. Lassa fever encephalitis
Mycobacterium avium - intracellulare
EBV
Arenavirus - spread by mice
Ceftriaxone

35. California encephalitis
Topical miconazole - selenium sulfide
S. epidermidis sensitive. S. saprophyticus resistant.
Bunyavirus
Bunyavirus - hemorrhagic fever - pneumonia

36. Influenza virus
Enveloped - SS - - linear - Helical
Taenid solium
Orthomyxovirus
Enveloped - SS + - Icosahedral

37. Protein A
Paramyxovirus
S. aureus. Binds Fc region of Ig. Prevents opsonization and phagocytosis.
ADP ribosylating A- B toxin inactivates EF-2
Group A beta - hemolytic strep (S. pyogenes) sensitive. Group B (S. agalactiae) resistant.

38. Erythrogenic exotoxin of strep pyogenes: Plasmid - lysogeny - bacterial chromosome?
Lysogeny
Paramyxovirus
Watery diarrhea
Necator americanus

39. Used in RSV to neutralize F protein
Flavivirus
Palivizumab
Coxiella burnetti
Rifampin

40. RSV
Erythromycin
P. vivax/ovale
Rubeola
Paramyxovirus

41. Fever then rash
HHV-6 (Roseola)
Metronidazole
Plasmid
Rifampin

42. Coronaviruses
Cryptosporidium spp.
Rubella
Calicivirus
Enveloped - SS + - Icosahedral

43. Eggs in dog feces when ingested can cause cysts in liver; causes anaphylaxis if Ags are released from cysts (surgeons inject ethanol before removal to neutralize Ags).
Schistosoma
Mucor or Rhizopus spp.
Echinococcus granulosus
Enveloped - SS + - Icosahedral

44. C. tetani exotoxin: Plasmid - lysogeny - bacterial chromosome?
Erythromycin
CMV
Toxocara canis
Plasmid

45. River blindness
Giardia lamblia
Clonorchis sinensis
Reovirus
Onchocerca volvulus

46. Eaton's agar
Coxiella burnetti
Paramyxovirus
Bunyavirus
Mycoplasma pneumonia

47. Transmitted by female blackflies; causes hyperpigmented skin. Can have allergic reaction to microfilaria
Ancylostoma duodenale - Necator americanus
Rubella
Giardia lamblia
Onchocerca volvulus

48. Novobiocin
S. pneumoniae sensitive - S. viridans resistant
Picornavirus
S. epidermidis sensitive. S. saprophyticus resistant.
Clostridium difficile - gas gangrene - double zone of hemolysis on blood agar

49. Flavivirus
Enveloped - SS + - Icosahedral
Flavivirus
Enveloped - SS+ - linear - icosahedral
Cryptococcus neoformans

50. Parasite: Liver cysts
Reovirus
HPV
Echinococcus granulosus
Yellow fever