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Microbiology 2

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Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Protozoa: Bloating - flatulence - foul - smelling - fatty diarrhea
Plasmid
Colonic epithelial cell necrosis and stimulation of fibrin deposition
ADP ribosylating A- B toxin inactivates EF-2
Giardia lamblia

2. Treatment for Tinea versicolor
Picornavirus
Clonorchis sinensis
Trichinella spiralis
Topical miconazole - selenium sulfide

3. Undercooked fish
Clonorchis sinensis
Cleaves host cell rRNA (inactivates 60S ribosome); enhances cytokine release - causing HUS.
Fluconazole or ketoconazole
Bunyavirus

4. Ingestion of larvae in raw freshwater fish. Causes vitamin B12 defic anemia.
Bunyavirus
Diphyllobothrium latum
Necator americanus
Cleaves host cell rRNA (inactivates 60S ribosome); enhances cytokine release - causing HUS.

5. Tx for Diphyllobothrium latum
Diethylcarbamazine
Trypanosoma (T. gambiense - T. rhodiesiense); African sleeping sickness
Praziquantel
Arenavirus

6. Tx for neurocystercercosis
Rifampin
P. vivax/ovale
Enveloped - SS+ - linear - icosahedral
bendazoles

7. Parasite: Liver cysts
Togavirus
Echinococcus granulosus
S. aureus. Binds Fc region of Ig. Prevents opsonization and phagocytosis.
Rubella

8. Cytotoxin B
C. Difficile
Enterobius vermicularis
Coxackie A - syphilis - Rocky Mountain spotted fever
Ascaris lumbricoides

9. Cholangiocarcinoma
Ancylostoma duodenale - Necator americanus
Icosohedral (double)
Rubeola
Clonorchis sinensis

10. River blindness
Cryptococcus neoformans
Aseptic meningitis - herpangina - mycarditis
Itraconazole or potassium iodide
Onchocerca volvulus

11. Sandfly/Rift valley fevers
Bunyavirus
Itraconazole or potassium iodide
Clonorchis sinensis
Quinine - clindamycin

12. Corynebacterium diptheria toxin
Cryptosporidium spp.
ADP ribosylating A- B toxin inactivates EF-2
Fluconazole or ketoconazole
Ancylostoma duodenale - Necator americanus

13. Norwalk virus - viral gastroenteritis
Taenid solium
Calicivirus
Rubeola
Pneumocystis jiroveci

14. Eggs in dog feces when ingested can cause cysts in liver; causes anaphylaxis if Ags are released from cysts (surgeons inject ethanol before removal to neutralize Ags).
Clonorchis sinensis
Paramyxoviruses
Pneumocystis jiroveci
Echinococcus granulosus

15. Tx for RSV
Strongyloides stercoralis
Ribavirin
Trypanosoma (T. gambiense - T. rhodiesiense); African sleeping sickness
Onchocerca volvulus

16. Influenza virus
Icosohedral (double)
Loa Loa
Orthomyxovirus
Cryptococcus neoformans

17. Enterotoxin A
Group A beta - hemolytic strep (S. pyogenes) sensitive. Group B (S. agalactiae) resistant.
S. epidermidis sensitive. S. saprophyticus resistant.
Togavirus
C. Difficile

18. Hookworms
Lysogeny
Enveloped - SS - - circular - 3 segments - helical
Necator americanus
Cryptosporidium spp.

19. Rubeola
Babesia
Paramyxovirus
P. vivax/ovale
Enveloped - SS+ - linear - icosahedral

20. Treatment for systemic infection by systemic mycoses
No envelope - SS + linear - Icosahedral
Ivermectin
Amphotericin B
Cryptococcus neoformans

21. HIV - Meningitis; India ink stain reveals narrow - based budding
Cryptococcus neoformans
Schistosoma mansoni
Invasive aspergillosis
Wuchereria bancrofti

22. Pinworm
CMV
P. falciparum
Enterobius vermicularis
Flavivirus

23. Hepevirus
No envelope - SS + linear - Icosahedral
HHV-8
Pneumocystis jiroveci
Rubeola

24. Rotavirus
Aseptic meningitis - herpangina - mycarditis
Rubeola
Reovirus
Bartonella henselae (bacillary angiomatosis)

25. 'Soap bubble' lesion in brain
Cryptococcus neoformans
Clonorchis sinensis
Sodium stibogluconate
CMV

26. Undercooked meat (pork)
C. Difficile
Coxackie A - syphilis - Rocky Mountain spotted fever
Trichinella spiralis
Cryptococcus neoformans

27. Fever and hemolytic anemia; predominantly in NE USA
HHV-8
Ancylostoma - Necator
Babesia
Deltavirus

28. Protein A
Cryptococcus neoformans
Trichinella spiralis
Enterobius vermicularis
S. aureus. Binds Fc region of Ig. Prevents opsonization and phagocytosis.

29. Arenaviruses
Lysogeny
Enveloped - SS - - linear - Helical
HHV-8
Enveloped - SS - - circular - 2 segments - helical

30. Erythrogenic exotoxin of strep pyogenes: Plasmid - lysogeny - bacterial chromosome?
Enveloped - SS - - circular - helical
Lysogeny
HHV-8
Paramyxovirus

31. Tx of Paragonimus westermani
Taenid solium
Praziquantel
Toxoplasma gondii
Flavivirus

32. St. Louis encephalitis
Flavivirus
Strongyloides stercoralis
Cleaves host cell rRNA (inactivates 60S ribosome); enhances cytokine release - causing HUS.
Ancylostoma duodenale - Necator americanus

33. All contain surface F 'fusion' protein
Onchocerca volvulus
Paramyxovirus
Paramyxoviruses
Yellow fever

34. Cycles occuring every other day; dormant form in liver -> tx w/primaquine
Enveloped - SS - - circular - 2 segments - helical
P. vivax/ovale
Colonic epithelial cell necrosis and stimulation of fibrin deposition
Necator americanus

35. 3- day rash
Paramyxovirus
Enveloped - SS - - circular - 2 segments - helical
Rubella
Picornavirus

36. Coxackievirus
Enveloped - SS - - linear - nonsegmented - Helical
Praziquantel
Most common cause of aseptic meningitis
Picornavirus

37. Shiga toxin
Mucor or Rhizopus spp.
Flavivirus
Stains cryptococcus neoformans red
Cleaves host cell rRNA (inactivates 60S ribosome); enhances cytokine release - causing HUS.

38. Kala - azar: spiking fevers - hepatosplenomegaly - pancytopenia
Metronidazole
Clostridium difficile - gas gangrene - double zone of hemolysis on blood agar
Rubella
Leishmania donovani

39. Cytotoxin B
Togavirus
Colonic epithelial cell necrosis and stimulation of fibrin deposition
Loa Loa
Paramyxovirus

40. Coxackievirus
Aseptic meningitis - herpangina - mycarditis
Doxycycline - ceftriaxone
Diphyllobothrium latum
Ivermectin

41. Flavivirus
Enveloped - SS+ - linear - icosahedral
Mucor or Rhizopus spp.
Clonorchis sinensis
Lysogeny

42. Shiga toxin: Plasmid - lysogeny - bacterial chromosome?
Bacterial chromosome
Diethylcarbamazine
Ivermectin
Congenital rubella

43. Tx for Legionella pneumophila
C. Difficile
Praziquantel
Erythromycin
Sodium stibogluconate

44. Female mosquito; causes blockage of lymphatic vessels (elephantitis). Takes 9 months to 1 year after bite to get elephantiasis sx.
Trichinella spiralis
Wuchereria bancrofti
Picornavirus
Rubeola

45. Coronaviruses
Lysogeny
Enveloped - SS + - Icosahedral
Lysogeny
Pasteurella multocida

46. Triad of chorioretinitis - hydrocephalus - intracranial calcifications
Lysogeny
Fluconazole or ketoconazole
Congenital Toxoplasma gondii
Sodium stibogluconate

47. IgA protease
Cleaves IgA. S. pneumoniae - H. influenzae type B - Neisseria (SHiN) in order to colonize respiratory mucosa.
HHV-6 (Roseola)
Rubeola
Enveloped - SS - - circular - 2 segments - helical

48. Echovirus
Most common cause of aseptic meningitis
Stains cryptococcus neoformans red
Ancylostoma duodenale - Necator americanus
JC virus (PML) results in demyelination

49. Tx for Toxocara canis
Amphotericin B
Ancylostoma - Necator
Diethylcarbamazine
Bacterial chromosome

50. Tx for Trypanosoma cruzi
Trichinella spiralis
Enveloped - SS + - Icosahedral
Nifurtimox
CMV