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Microbiology 2

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Rubella
Pasteurella multocida
Togavirus
Flavivirus
Reovirus

2. Sandfly/Rift valley fevers
Enveloped - SS + - Icosahedral
Nonenveloped - SS + - Icosahedral
Aseptic meningitis - herpangina - mycarditis
Bunyavirus

3. River blindness
P. vivax/ovale
Togavirus
Clostridium difficile - gas gangrene - double zone of hemolysis on blood agar
Onchocerca volvulus

4. Protein A
Trichomonas vaginalis
S. aureus. Binds Fc region of Ig. Prevents opsonization and phagocytosis.
HHV-6 (Roseola)
Mycobacterium avium - intracellulare

5. Ebola/Marburg hemorrhagic fever
Rubeola
Filovirus
Trichinella spiralis
Picornavirus

6. Subacute sclerosing panencephalitis
Rubeola
Trichinella spiralis
Enveloped - SS+ - linear - icosahedral
Colonic epithelial cell necrosis and stimulation of fibrin deposition

7. Coxackievirus
Picornavirus
EBV
Aseptic meningitis - herpangina - mycarditis
Ancylostoma - Necator

8. HIV - Abscesses - ring - enhancing lesions on imaging
Necator americanus
Pasteurella multocida
Toxoplasma gondii
Ancylostoma - Necator

9. Lyme disease

10. Enterotoxin A
DS linear 10-12 segments
Toxoplasma gondii
Watery diarrhea
No envelope - SS + linear - Icosahedral

11. Coxackievirus
CMV
Enveloped - SS + - Icosahedral
Enveloped - SS - - linear - 8 segments - Helical
Picornavirus

12. Used in RSV to neutralize F protein
Babesia
Palivizumab
Cleaves host cell rRNA (inactivates 60S ribosome); enhances cytokine release - causing HUS.
Clonorchis sinensis

13. Arenaviruses
Picornavirus
Cryptosporidium spp.
Enveloped - SS - - circular - 2 segments - helical
Group A beta - hemolytic strep (S. pyogenes) sensitive. Group B (S. agalactiae) resistant.

14. RSV
Paramyxovirus
Fluconazole or ketoconazole
JC virus (PML) results in demyelination
Plasmid

15. Tx of Clonorchis sinensis
Congenital Toxoplasma gondii
Reovirus
Coxiella burnetti
Praziquantel

16. Treatment for systemic infection by systemic mycoses
Echinococcus granulosus
Amphotericin B
Enveloped - SS - - circular - 2 segments - helical
Leishmania donovani

17. Eaton's agar
No envelope - SS + linear - Icosahedral
Diethylcarbamazine
P. vivax/ovale
Mycoplasma pneumonia

18. Causes inflammation of the biliary tract -> pigmented gallstones
Clonorchis sinensis
Coxackie A - syphilis - Rocky Mountain spotted fever
Cryptococcus neoformans
Ceftriaxone

19. California encephalitis
Bunyavirus
P. vivax/ovale
Praziquantel
S. epidermidis sensitive. S. saprophyticus resistant.

20. Tx for Onchocerca volvulus
Schistosoma mansoni
Dracunculus medinensis
Loa Loa
Ivermectin

21. Botulinum exotoxin: Plasmid - lysogeny - bacterial chromosome?
Bunyavirus
Paramyxovirus
Lysogeny
Enterobius vermicularis

22. HIV - Superficial neoplastic proliferation of vasculature; biopsy reveals lymphocytic inflammation
HHV-8
Echinococcus granulosus
Watery diarrhea
Enveloped - SS+ - linear - icosahedral

23. Retroviruses
Deltavirus
Bunyavirus
Enveloped - SS + - Icosahedral
Cryptococcus neoformans

24. Parasite: Hematuria - bladder CA
Schistosoma haematobium
Lysogeny
Paramyxovirus
Bunyavirus

25. Mucicarmine
Picornavirus
Stains cryptococcus neoformans red
Naegleria fowleri
Loa Loa

26. Treatment for local infection by systemic mycoses
Fluconazole or ketoconazole
Trichinella spiralis
Lysogeny
Aseptic meningitis - herpangina - mycarditis

27. 3- day rash
Aminoglycoside plus extended spectrum penicillin (piperacillin - ticarcillin)
Togavirus
Rubella
Reovirus

28. Ingestion of larvae in raw freshwater fish. Causes vitamin B12 defic anemia.
Diphyllobothrium latum
Congenital rubella
Nifurtimox
Echinococcus granulosus

29. Tx for neurocystercercosis
bendazoles
HHV-6 (Roseola)
Rifampin
Pseudomonas - inactivates EF-2

30. Poliovirus
Picornavirus
bendazoles
Paramyxovirus
Dracunculus medinensis

31. Parasite: Portal hypertension
Coxackie A - syphilis - Rocky Mountain spotted fever
Pasteurella multocida
Schistosoma mansoni
Paramyxovirus

32. Parasite: Microcytic anemia
Taenid solium
Ancylostoma - Necator
Enveloped - SS+ - linear - icosahedral
EBV

33. Influenza virus
Enveloped - SS - - linear - 8 segments - Helical
Orthomyxovirus
Rubeola
No envelope

34. HIV - Pleuritic pain - hemoptysis - infiltrates on imaging
EBV
T. pertenue
Clostridium difficile - gas gangrene - double zone of hemolysis on blood agar
Invasive aspergillosis

35. Rubeola
Heart block - bilateral Bell's palsy
Lysogeny
Ancylostoma duodenale - Necator americanus
Paramyxovirus

36. Eggs visible in feces; intestinal infection
Bunyavirus
Yellow fever
Trypanosoma (T. gambiense - T. rhodiesiense); African sleeping sickness
Ascaris lumbricoides

37. Hepevirus
Calicivirus
Group A streptococcus. Helps prevent phagocytosis.
No envelope - SS + linear - Icosahedral
Arenavirus

38. HIV - Squamous cell carcinoma; often in anus (MSM) or cervix (females)
Watery diarrhea
HPV
Bartonella henselae (bacillary angiomatosis)
Clostridium difficile - gas gangrene - double zone of hemolysis on blood agar

39. Severe congenital infection
Rubella
bendazoles
Rubeola
Bunyavirus

40. Undercooked meat (pork)
Enveloped - SS - - circular - helical
Trichinella spiralis
Mucor or Rhizopus spp.
Enveloped - SS - - linear - 8 segments - Helical

41. Pinworm
Enterobius vermicularis
Ivermectin
Pseudomonas - inactivates EF-2
HHV-6 (Roseola)

42. HIV - Meningitis; India ink stain reveals narrow - based budding
Yellow fever
Cryptococcus neoformans
Pseudomonas - inactivates EF-2
Paragonimus westermani

43. Togavirus
No envelope
Enveloped - SS+ - linear - icosahedral
Enveloped - SS - - linear - Helical
Nystatin

44. Ingestion of larvae encysted in undercooked pork. Cysticercosis and neurocysticercosis - mass lesions in brain.
Bunyavirus
Rubeola
Fluconazole or ketoconazole
Taenid solium

45. Rash spreads from head to toe
Coxiella burnetti
Rubeola
Reovirus
Aminoglycoside plus extended spectrum penicillin (piperacillin - ticarcillin)

46. Opportunistic fungal infection in ketoacidotic diabetic or leukemic patients
Amphotericin B
HHV-6 (Roseola)
Necator americanus
Mucor or Rhizopus spp.

47. Shiga toxin
Cleaves host cell rRNA (inactivates 60S ribosome); enhances cytokine release - causing HUS.
Clostridium difficile - gas gangrene - double zone of hemolysis on blood agar
Paramyxovirus
Schistosoma

48. Tx for RSV
Naegleria fowleri
Icosohedral (double)
Ribavirin
Lysogeny

49. Rickettsia transmitted by aerosol; no rash - no vector - neg Weil - Felix
Nonenveloped - SS + - Icosahedral
Plasmid
EBV
Coxiella burnetti

50. Eastern equine encephalitis
P. falciparum
Togavirus
S. epidermidis sensitive. S. saprophyticus resistant.
Picornavirus