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Microbiology 2

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Norwalk virus - viral gastroenteritis
Wuchereria bancrofti
Paramyxoviruses
Calicivirus
Necator americanus

2. Larvae penetrateskin of feet; intestinal infection can cause anemia (suck blood from intestinal walls).
Mucor or Rhizopus spp.
Reovirus
Ancylostoma duodenale - Necator americanus
Picornavirus

3. Filoviruses
Picornavirus
C. Difficile
Loa Loa
Enveloped - SS - - linear - Helical

4. HIV - Pneumonia CD4<200
Deltavirus
Pneumocystis jiroveci
Enveloped - SS - - circular - helical
Rubeola

5. Yellow fever
Flavivirus
Retrovirus
Lysogeny
Group A beta - hemolytic strep (S. pyogenes) sensitive. Group B (S. agalactiae) resistant.

6. Mucicarmine
DS linear 10-12 segments
Congenital Toxoplasma gondii
Enveloped - SS - - circular - helical
Stains cryptococcus neoformans red

7. Optochin
Ancylostoma duodenale - Necator americanus
Mucor or Rhizopus spp.
S. pneumoniae sensitive - S. viridans resistant
Enterobius vermicularis

8. Coxackievirus
Picornavirus
Arenavirus
C. Difficile
Group A beta - hemolytic strep (S. pyogenes) sensitive. Group B (S. agalactiae) resistant.

9. Yaws
T. pertenue
Flavivirus
Entamoeba histolytica
JC virus (PML) results in demyelination

10. Calicivirus
Trichomonas vaginalis
Dracunculus medinensis
Pseudomonas - inactivates EF-2
No envelope - SS + linear - Icosahedral

11. Food contaminated with eggs; intestinal infection; causes anal pruritis
Colonic epithelial cell necrosis and stimulation of fibrin deposition
Schistosoma mansoni
Enterobius vermicularis
Toxoplasma gondii

12. Western equine encephalitis
Togavirus
Nifurtimox
Lysogeny
C. Difficile

13. Rash preceded by cough - coryza - conjunctivitis
Necator americanus
HHV-6 (Roseola)
Rubeola
Pseudomonas - inactivates EF-2

14. In drinking water; skin inflammation and ulceration.
Togavirus
Dracunculus medinensis
Enterobius vermicularis
C. Difficile

15. Tx for Taenid solium
Pasteurella multocida
Diethylcarbamazine
Rubella
Praziquantel

16. Parasite: Liver cysts
No envelope
S. pneumoniae sensitive - S. viridans resistant
Toxoplasma gondii
Echinococcus granulosus

17. Tx for Loa Loa
Pseudomonas - inactivates EF-2
Diethylcarbamazine
Entamoeba histolytica
Cryptococcus neoformans

18. M protein
Ivermectin
Group A streptococcus. Helps prevent phagocytosis.
Enveloped - SS - - linear - 8 segments - Helical
Pasteurella multocida

19. Subacute sclerosing panencephalitis
Bunyavirus
ADP ribosylating A- B toxin inactivates EF-2
Colonic epithelial cell necrosis and stimulation of fibrin deposition
Rubeola

20. Echovirus
Rubella
Most common cause of aseptic meningitis
Paramyxovirus
Cleaves host cell rRNA (inactivates 60S ribosome); enhances cytokine release - causing HUS.

21. Deltaviruses
Enveloped - SS - - circular - helical
Echinococcus granulosus
Cryptosporidium spp.
Enveloped - SS - - circular - 2 segments - helical

22. Tx for Onchocerca volvulus
Ivermectin
EBV
Dracunculus medinensis
Rifampin

23. Togavirus
Schistosoma
Yellow fever
Enveloped - SS+ - linear - icosahedral
Most common cause of aseptic meningitis

24. O Ag of Salmonella: Plasmid - lysogeny - bacterial chromosome?
Lysogeny
Rubeola
Pasteurella multocida
Yellow fever

25. HIV - Superficial neoplastic proliferation of vasculature; biopsy reveals lymphocytic inflammation
HHV-8
Rubeola
Metronidazole
Praziquantel

26. HIV - Abscesses - ring - enhancing lesions on imaging
Enveloped - SS - - linear - Helical
Cryptosporidium spp.
Clonorchis sinensis
Toxoplasma gondii

27. Inflammation of muscle (larvae encyst in muscle)
No envelope - SS + linear - Icosahedral
Trichinella spiralis
No envelope - SS + linear - Icosahedral
Reovirus

28. Fever then rash
Echinococcus granulosus
HHV-6 (Roseola)
Giardia lamblia
Nystatin

29. Fever and hemolytic anemia; predominantly in NE USA
Babesia
Metronidazole
Schistosoma haematobium
Diethylcarbamazine

30. Larvae in soil penetrate skin; lung sx; intestinal infection; causes vomiting - diarrhea - and anemia - abdominal bloating - weight loss.
Strongyloides stercoralis
Retrovirus
Trichinella spiralis
Group A beta - hemolytic strep (S. pyogenes) sensitive. Group B (S. agalactiae) resistant.

31. HIV - Non - hodgkin's lymphoma (large cell type); often on oropharynx (Waldeyer's ring)
Togavirus
EBV
Aminoglycoside plus extended spectrum penicillin (piperacillin - ticarcillin)
DS linear 10-12 segments

32. Tx for Leishmania donovani
Cleaves IgA. S. pneumoniae - H. influenzae type B - Neisseria (SHiN) in order to colonize respiratory mucosa.
Sodium stibogluconate
Pneumocystis jiroveci
Arenavirus - spread by mice

33. Treatment for Sporothrix schenckii
Itraconazole or potassium iodide
Nystatin
Lysogeny
Mycobacterium avium - intracellulare

34. Rubella
Picornavirus
DS linear 10-12 segments
Togavirus
P. vivax/ovale

35. Exotoxin A
C. Difficile
Pseudomonas - inactivates EF-2
Bunyavirus
Paragonimus westermani

36. California encephalitis
Togavirus
Paramyxoviruses
Bunyavirus
Cryptococcus neoformans

37. Corynebacterium diptheria toxin
ADP ribosylating A- B toxin inactivates EF-2
C. Difficile
Enveloped - SS - - circular - helical
Invasive aspergillosis

38. LCMV - lymphocytic choriomeningitis virus
Arenavirus
Ivermectin
Praziquantel
Bunyavirus - hemorrhagic fever - pneumonia

39. Cycles occuring every other day; dormant form in liver -> tx w/primaquine
Congenital Toxoplasma gondii
Lysogeny
P. vivax/ovale
Cryptococcus neoformans

40. Kala - azar: spiking fevers - hepatosplenomegaly - pancytopenia
Cryptococcus neoformans
Mycobacterium avium - intracellulare
Leishmania donovani
Trichinella spiralis

41. Prophylaxis in close contacts of pts w/Haemophilus influenzae meningitis
Cryptococcus neoformans
C. Difficile
No envelope - SS + linear - Icosahedral
Rifampin

42. Treatment for superficial candida infection
Naegleria fowleri
Echinococcus granulosus
Nystatin
Ascaris lumbricoides

43. Eggs in dog feces when ingested can cause cysts in liver; causes anaphylaxis if Ags are released from cysts (surgeons inject ethanol before removal to neutralize Ags).
Pseudomonas - inactivates EF-2
EBV
Echinococcus granulosus
Amphotericin B

44. Giant roundworm
S. pneumoniae sensitive - S. viridans resistant
Giardia lamblia
Icosohedral (double)
Ascaris lumbricoides

45. Protozoa: Bloating - flatulence - foul - smelling - fatty diarrhea
T. pertenue
Bacterial chromosome
Ascaris lumbricoides
Giardia lamblia

46. Alpha toxin
Babesia
Bartonella henselae (bacillary angiomatosis)
Praziquantel
Clostridium difficile - gas gangrene - double zone of hemolysis on blood agar

47. HAV
Toxocara canis
Ancylostoma - Necator
Pathognomonic for measles or live attenuated vaccine
Picornavirus

48. Treatment for systemic candida infection
Lysogeny
Nifurtimox
Amphotericin B
Enveloped - SS+ - linear - icosahedral

49. Sabouraud's agar
Topical miconazole - selenium sulfide
Aminoglycoside plus extended spectrum penicillin (piperacillin - ticarcillin)
Cryptococcus neoformans
Enveloped - SS + - Icosahedral

50. HIV - Chronic watery diarrhea; acid - fast cysts seen in stool
Plasmid
Naegleria fowleri
Cryptosporidium spp.
Schistosoma haematobium