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Microbiology 2

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Retroviruses
Schistosoma haematobium
Reovirus
Pathognomonic for measles or live attenuated vaccine
Enveloped - SS + - Icosahedral

2. Tx for Babesia
Heart block - bilateral Bell's palsy
Quinine - clindamycin
Enveloped - SS+ - linear - icosahedral
bendazoles

3. Pinworm
Togavirus
Ascaris lumbricoides
Enterobius vermicularis
Picornavirus

4. Maltese cross in RBC
Filovirus
Most common cause of aseptic meningitis
Enveloped - SS - - circular - 3 segments - helical
Babesia

5. Inflammation of muscle (larvae encyst in muscle)
Dracunculus medinensis
Bartonella henselae (bacillary angiomatosis)
Flavivirus
Trichinella spiralis

6. 'swiss cheese' appearance in brain
Taenid solium
Clonorchis sinensis
Itraconazole or potassium iodide
Palivizumab

7. Kala - azar: spiking fevers - hepatosplenomegaly - pancytopenia
Doxycycline - ceftriaxone
Invasive aspergillosis
Leishmania donovani
Metronidazole

8. Rhinovirus
Flavivirus
Picornavirus
Congenital Toxoplasma gondii
Colonic epithelial cell necrosis and stimulation of fibrin deposition

9. O Ag of Salmonella: Plasmid - lysogeny - bacterial chromosome?
Congenital rubella
Lysogeny
Picornavirus
Paramyxovirus

10. Togavirus
Praziquantel
Enveloped - SS+ - linear - icosahedral
Schistosoma haematobium
S. epidermidis sensitive. S. saprophyticus resistant.

11. 3- day rash
Invasive aspergillosis
Diphyllobothrium latum
Rubella
Bunyavirus

12. Tx for RSV
Ribavirin
Paramyxoviruses
Wuchereria bancrofti
Paramyxovirus

13. HTLV
Enveloped - SS - - linear - Helical
Retrovirus
Enveloped - SS+ - linear - icosahedral
Bunyavirus - hemorrhagic fever - pneumonia

14. Hantavirus
Ascaris lumbricoides
Lysogeny
Bunyavirus - hemorrhagic fever - pneumonia
Bunyavirus

15. Protozoa: Bloody diarrhea - liver abscess - RUQ pain
Lysogeny
Entamoeba histolytica
DS linear 10-12 segments
Most common cause of aseptic meningitis

16. HIV - TB like dz CD4<50
Mycobacterium avium - intracellulare
Enveloped - SS - - linear - nonsegmented - Helical
Ascaris lumbricoides
Rubella

17. Shiga toxin: Plasmid - lysogeny - bacterial chromosome?
Bacterial chromosome
No envelope - SS + linear - Icosahedral
Schistosoma haematobium
Icosohedral (double)

18. Rickettsia transmitted by aerosol; no rash - no vector - neg Weil - Felix
Paragonimus westermani
Coxiella burnetti
Wuchereria bancrofti
Ribavirin

19. Dengue fever
Echinococcus granulosus
Flavivirus
Cryptosporidium spp.
Pathognomonic for measles or live attenuated vaccine

20. Paramyxoviruses
Toxoplasma gondii
Enveloped - SS - - linear - nonsegmented - Helical
Enveloped - SS - - linear - Helical
Aminoglycoside plus extended spectrum penicillin (piperacillin - ticarcillin)

21. Subacute sclerosing panencephalitis
Cleaves host cell rRNA (inactivates 60S ribosome); enhances cytokine release - causing HUS.
Group A streptococcus. Helps prevent phagocytosis.
Clonorchis sinensis
Rubeola

22. HIV - Superficial neoplastic proliferation of vasculature; biopsy reveals lymphocytic inflammation
Enveloped - SS + - Icosahedral
Flavivirus
Babesia
HHV-8

23. Tx for Trichomonas vaginalis
S. aureus. Binds Fc region of Ig. Prevents opsonization and phagocytosis.
Metronidazole
Paramyxovirus
Ivermectin

24. Protozoa: Rapidly fatal meningoencephalitis
Nonenveloped - SS + - Icosahedral
Amphotericin B
Icosohedral (double)
Naegleria fowleri

25. Yaws
Deltavirus
T. pertenue
Fluconazole or ketoconazole
S. pneumoniae sensitive - S. viridans resistant

26. HIV - Chronic watery diarrhea; acid - fast cysts seen in stool
CMV
Cryptosporidium spp.
Arenavirus - spread by mice
Pneumocystis jiroveci

27. HIV - Pleuritic pain - hemoptysis - infiltrates on imaging
Praziquantel
T. pertenue
Invasive aspergillosis
Leishmania donovani

28. Opportunistic fungal infection in ketoacidotic diabetic or leukemic patients
Mucor or Rhizopus spp.
Trichinella spiralis
CMV
EBV

29. Larvae in soil penetrate skin; lung sx; intestinal infection; causes vomiting - diarrhea - and anemia - abdominal bloating - weight loss.
Strongyloides stercoralis
No envelope - SS + linear - Icosahedral
Invasive aspergillosis
Nonenveloped - SS + - Icosahedral

30. Dilated cardiomyopathy - megacolon - megaesophagus
Coxiella burnetti
Echinococcus granulosus
Enveloped - SS+ - linear - icosahedral
Trypansoma cruzi. Chagas dz - S. America

31. Parasite: Hematuria - bladder CA
Trichinella spiralis
Enveloped - SS - - linear - 8 segments - Helical
Schistosoma
Schistosoma haematobium

32. Influenza virus
Bacterial chromosome
Bunyavirus
Aminoglycoside plus extended spectrum penicillin (piperacillin - ticarcillin)
Orthomyxovirus

33. Larvae penetrateskin of feet; intestinal infection can cause anemia (suck blood from intestinal walls).
Ancylostoma duodenale - Necator americanus
Enterobius vermicularis
Trichinella spiralis
Clonorchis sinensis

34. Councilman bodies (acidophilic inclusions) in liver
No envelope - SS + linear - Icosahedral
Aseptic meningitis - herpangina - mycarditis
Yellow fever
Enveloped - SS - - linear - nonsegmented - Helical

35. Fever then rash
Entamoeba histolytica
HHV-6 (Roseola)
Diethylcarbamazine
Nystatin

36. HDV
Rubeola
Bunyavirus - hemorrhagic fever - pneumonia
Giardia lamblia
Deltavirus

37. Reovirus
S. epidermidis sensitive. S. saprophyticus resistant.
Rubella
S. pneumoniae sensitive - S. viridans resistant
Icosohedral (double)

38. Bacitracin
Metronidazole
Lysogeny
Retrovirus
Group A beta - hemolytic strep (S. pyogenes) sensitive. Group B (S. agalactiae) resistant.

39. Periorbital edema
Heart block - bilateral Bell's palsy
Taenid solium
Topical miconazole - selenium sulfide
Trichinella spiralis

40. Tx for Echinococcus granulosus
Coxackie A - syphilis - Rocky Mountain spotted fever
bendazoles
Lysogeny
Nifurtimox

41. Enterotoxin A
C. Difficile
P. vivax/ovale
Stains cryptococcus neoformans red
Cryptosporidium spp.

42. Tx of Clonorchis sinensis
Echinococcus granulosus
Praziquantel
Itraconazole or potassium iodide
Echinococcus granulosus

43. Transmitted by female blackflies; causes hyperpigmented skin. Can have allergic reaction to microfilaria
Aseptic meningitis - herpangina - mycarditis
No envelope - SS + linear - Icosahedral
Group A streptococcus. Helps prevent phagocytosis.
Onchocerca volvulus

44. Coronaviruses
ADP ribosylating A- B toxin inactivates EF-2
Onchocerca volvulus
Enveloped - SS + - Icosahedral
Heart block - bilateral Bell's palsy

45. Coxackievirus
Ancylostoma - Necator
Picornavirus
Aseptic meningitis - herpangina - mycarditis
Clonorchis sinensis

46. Organisms causing rash on palms and soles
Loa Loa
Picornavirus
Enterobius vermicularis
Coxackie A - syphilis - Rocky Mountain spotted fever

47. Mucicarmine
Pneumocystis jiroveci
Cleaves host cell rRNA (inactivates 60S ribosome); enhances cytokine release - causing HUS.
No envelope - SS + linear - Icosahedral
Stains cryptococcus neoformans red

48. Parasite: Liver cysts
Schistosoma mansoni
Taenid solium
Diethylcarbamazine
Echinococcus granulosus

49. Tx for Lyme dz
Flavivirus
Doxycycline - ceftriaxone
Picornavirus
Schistosoma

50. HIV - Pneumonia CD4<200
Paramyxovirus
Cleaves IgA. S. pneumoniae - H. influenzae type B - Neisseria (SHiN) in order to colonize respiratory mucosa.
Togavirus
Pneumocystis jiroveci