Microbiology Board

Instructions:

• Answer 50 questions in 15 minutes.
• If you are not ready to take this test, you can study here.
• Match each statement with the correct term.
• Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Cell conjugation
Tetanus by blocking inhibitory GABA and glycine - (GABA in brain - glycine in spinal cord)
plasmid DNA transfer via sex pilus - bestows antimicrobial resistance
Brody's abcess
for gram negative - competes with PABA


2. Leptospira

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3. Lewy bodies are inclusion bodies associated with...

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4. Silver nitrate

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5. Double blind study
dysentery
dyptheria - gray pseudomembrane in throat - pleomorphic - many shapes - chinese characters
eliminates placebo
Strep pyogenes


6. What is the purpose of complement system?
Classified streptococcus
salk - rabies
enhances phagocytosis or cellular lysis
for gram negative - competes with PABA


7. Pseudomonas
bubonic plague
blue/green pus - warm moist places - most common pneumonia and cyclic fibrosis
developed the first microscope - saw microorganisms
fix gross specimens


8. What is the number one cause of impetigo and myelitis?
Ascholi test
Canine feces - found in dogs - wolves and humans - hydatid cysts in live and lung
genital herpes 'below the belt'
staph aureus


9. Prion
types I - IV - pneumonic = ACID (see future flash card)
rheumatic fever
Yellow fever
acellular protein which denatures other proteins - cannot be autoclaved - mad cow disease


10. Hepatitis A
Categorizes streptococcus demonstrates the type of hemolysis (destruction of RBCs)
follows dermatome
spread by food - self limiting
Influenza


11. Peritrichus

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12. Don't let mono get you down'
atypical lymphocytes
gonorrhea
was used for newborn's eyes (no longer used now - erythromycin instead) - prevents ophthalmia neonatorum (most common cause = gonorrhea)
toxin outside the cell from cellular waste products - heat labile - cook your food!


13. Natural passive immunity
TB
given antibody in utero - breastfeeding - in utero = IgG - breastfeeding = IgA
T-cell growth factor - made by CD4 cells - CD4 = T-Helper cell = 'quarterback' of immune system - directs response of immune system
for gram negative - competes with PABA


14. Mutualism
fish - mouth - contaminated sushi - may cause pernicious anemia (B12) - yellow fin tuna most commonly has it
toxin that affects the nervous system - ie. botulism - tetanus
atypical pneumonia - mycoplasms lacks cell wall
2 populations living together - both benefit


15. Guarneri bodies are inclusion bodies associated with...
small pox (variola)
rubella - rabies - Hep A
follows dermatome
for gram negative and positive - inhibits protein synthesis - turns teeth gray or yellow brown


16. Sabin
Live polio vaccine - given orally
Catalase
In liver - contaminated aquatic plants (ie kelp) - hemoptysis
BLCCSS (blocks) - Bacillus - Listeria monocytogenes - Clostridium - Corynebacterium diphtheriae - Staph - Strep


17. Enterobacteria
father of pathology and germ theory - rabies vaccine - disproved spontaneous generation - pasteurization of wine - then milk
causes diarrhea
developed smallpox vaccine
secondary


18. Widal lab test
spontaneous abortion in cattle
for typhoid fever
Many furuncles (infected hair follicles) - 'a CAR load of furuncles' - #1 cause is staph aureus
active = body must actively make antibodies - passive = body receives antibodies from outside source


19. D'Herelle - Felix
active = body must actively make antibodies - passive = body receives antibodies from outside source
discovered bacteriophage - an altered virus
single flagella on one pole
enhances phagocytosis or cellular lysis


20. Temperature and time for holding/batch method of pasteurization
145
heterophile agglutinization (Paul Bunnel) - Downey cell (don't let mono get you down) - monospot
single flagella on one pole
McCallums Patch


21. Flasciolopsis hepatica
hepatitis associated with alcoholism
Helps IgG
In liver - contaminated aquatic plants (ie kelp) - hemoptysis
stain for mycobacteria


22. MRSA =
antisepsis - used carbolic acid to sterilize surgical instruments
Methycilline resistant staph aureus - hospitals use vancomycin now
Mantoux test - tine test - skin prick test
staph aureus


23. Amphitrichus

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24. Councilman cells are inclusion bodies associated with...
metachromatic granules seen in diphtheria (pseudomembrane in throat)
Chemicals produced by cells - (I - II - III)
viral hepatitis
Strep pyogenes


25. Toxoid
Classified streptococcus
aquatic plants - contaminated snail feces gets into plants
Inactivated toxin (active artificial immunity)
river blindness - flies - in Africa


26. Diphyllobothrium latum
Injection of attenuated organism - ie. tetanus toxoid = inactivated portion that triggers immune system to make antibody
fish - mouth - contaminated sushi - may cause pernicious anemia (B12) - yellow fin tuna most commonly has it
tertiary syphilis
Most numerous - crosses placenta - anamnestic response 'without amnesia' - the body remembers from the last time you had the disease and secretes the same amount of IgG next time


27. Trichonella spiralis
5. sand filtration (removes anaerobic bacteria) 6. aeration (adds oxygen) 7. chlorination (kills remaining bacteria) 8. possible flouridation
measles (rubeola / red measles) - on buccal mucosa - white / bluish spots
Trichinosis - raw pork - lives in striated muscles - intercostals and diaphragm - diagnosed on x-ray especially gastrocnemius biopsy to confirm
most common cause of UTI - enterotoxic - 'traveller's disease' - E.coli 157 - enterohemorrhagic (meat)


28. Iwanowski
C3B complement
discovered the virus - tobacco mosaic virus was the first
Allergic reactions - increases in Hodgkins disease (Reed-Sternberg cells)
bacteriophage transfers genetic material between bacteria - bacteriophage = altered virus


29. Genus and species
Mantoux test - tine test - skin prick test
strawberry tongue
small pox (variola)
Indicate how the organisms are named - (King Paul Can Only Find Good Spices) Kingdom - Phylum - Class - Order - Family - Genus - Species


30. Gohn complex are inclusion bodies associated with...

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31. Interleukin III
C3B complement
Made by big bone marrow - in blood and lymph system
D= Dwarf H= Spreading M= Mucoid capsule forming - related to virulence O= compact (O vs H) R= Rough S= Smooth
bloody transfusions


32. Iodine
pre-op disinfectant
whooping cough
genital herpes 'below the belt'
Chocolate agar aka Thayer Martin agar aka heated blood agar


33. Tetracycline
secondary
for gram negative and positive - inhibits protein synthesis - turns teeth gray or yellow brown
Yellow fever
small pox (variola)


34. Leading cause of death world wide
Can only be in ONE environment - not the other - obligate aerobe = only in O2 - obligate anaerobe = only without O2
grown in candle jars culture
Goodpasteur
1 tuberculosis 2 malaria


35. What do heterotrophs eat?
bloody transfusions
Live polio vaccine - given orally
organic material
discovered the virus - tobacco mosaic virus was the first


36. Paul Bunnel lab test

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37. Primary water purification process
strawberry tongue
Strep pyogenes
mononucleosis
1. filtration 2. flocculation (aluminum salts) 3. sedimentation 4. sludge digestion (add anaerobic bacteria)


38. Lister
antisepsis - used carbolic acid to sterilize surgical instruments
Indicate how the organisms are organized and classified
(not research) - morbidity and epidemiology statistics
toxin from lipopolysaccharide layer of cell - heat stable - gram (-) have these


39. Haemophilis haemophilis
exposed to disease = body reacts - ie. measles - chicken pox triggers antibody production
Chemicals produced by cells - (I - II - III)
influenza
gonorrhea


40. Which vaccines are manufactured using chick peas?
Most common liver cancer - spread by dirty needles and sexual contact
Measles - mumps vaccine
discovered the virus - tobacco mosaic virus was the first
Chemicals produced by cells - (I - II - III)


41. Scarlet fever ak
5. sand filtration (removes anaerobic bacteria) 6. aeration (adds oxygen) 7. chlorination (kills remaining bacteria) 8. possible flouridation
Measles - mumps - rubella - Sabin
BLCCSS (blocks) - Bacillus - Listeria monocytogenes - Clostridium - Corynebacterium diphtheriae - Staph - Strep
strawberry tongue


42. Mycoplasm
whip worm ('whip those t's into shape) oral-fecal weight loss
atypical pneumonia - mycoplasms lacks cell wall
tertiary syphilis
mononucleosis


43. Streptomycin
red pus
for gram negative - inhibits protein synthesis
Monitors soil - air and water quality
influenza


44. NIH
Does research - (not stats)
5. sand filtration (removes anaerobic bacteria) 6. aeration (adds oxygen) 7. chlorination (kills remaining bacteria) 8. possible flouridation
toxin outside the cell from cellular waste products - heat labile - cook your food!
rheumatic fever


45. Type III hypersensitivity reaction
Helps IgG
exposed to disease = body reacts - ie. measles - chicken pox triggers antibody production
Controls FDA - CDC - US Public Health Services
I - Immune-complex mediated - IgG and complement [3 things = type III] = antigen + antibody + complement


46. What are the 5 diseases caused by staph aureus?
STOIC: Scalded skin syndrome (exfoliative toxin) - Toxic shockOsteomyelitis - Impetigo - Carbuncles [staph aureus produces alpha toxin aka alpha hemolysin]
Legionnaire disease - water droplets - pontiac disease
responsible for milk and milk products
father of pathology and germ theory - rabies vaccine - disproved spontaneous generation - pasteurization of wine - then milk


47. Flasciolopsis buski in intestines
1. filtration 2. flocculation (aluminum salts) 3. sedimentation 4. sludge digestion (add anaerobic bacteria)
Came up with washing hands before delivering baby and significantly reduced puerperal fever (aka childbed fever) - this can develop into sepsis - contracted by women after childbirth
for gram negative and positive - inhibits protein synthesis - turns teeth gray or yellow brown
aquatic plants - contaminated snail feces gets into plants


48. Koch

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49. Which vaccines are manufactured using monkey kidney tissue?
negri inclusion bodies - bullet shaped - leads to hydrophobia (throat hurts - so don't want to drink water - this why dogs foam at the mouth)
Bruten's A Gamma Globulin Anemia - (primary immune deficiency)
psuedomonas aeruginosa - open burn infection - unsanitized hot tub - fluoresces blue under UV light from pyocyanin and fluorescein pigment
polio


50. Escherichia E.coli

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