Test your basic knowledge |

Musculoskeletal

Instructions:

Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can study here.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. What nerve is injured in a fracutre of the hook of hamate
Ulnar nerve
Expansile glistening mass within the medullary cavity
Psoriatic arthritis - occurs is less than 1/3 of psoriasis pts
Large goints (knee)

2. What is the power stroke of muscle contraction
Expansile glistening mass within the medullary cavity
Sudden appearance of multiple sebhorrheic keratosis lesions indicating underlying lesions - GI or lymphoid
Myosin releases bound ADP and is displaced on the actin filament
SERMs - calcitonin - bisphosphates or pulsatile PTH for severe cases

3. On the palmar and dorsal sides of the hand - what dermatome covers the 5th finger and the lateral 1/2 of the 4th finger
Inc CK - inc aldolase - and positive ANA and anti Jo -1 - steroids
S100 - associated with sunligh exposure - fair skinned at risk - depth of tumor correlates with risk of mets - dark with irregular borders
Osteopetrosis - abnl fxn of osteoclasts
Ulnar

4. What is the Auspitz sign
Hyperkeratosis
Crohns and ulcerative colitis
In psoriasis - bleeding spots when scales are scraped off
Peroneal everts and dorsiflexes - foot dropPED; tibial inverts and plantarflexes - can't stand on Tip toes

5. What development failure can results in albinism
Upper trunk compression - biceps - brachialis - corachobrachialis - flexion of arm at elbow - sensory = lateraly forearm
NC migration
The dermis
Anti Scl70 - anti DNA topoisomerase I antibody

6. Which muscle is the most common rotator cuff injury and What does it do
Supraspinatus - abducts the arm before the deltoid
Strawberry hemangioma
Radial deviation of wrist upon flexion - ulnar claw hand - pope's blessing
Onion skin - 11:22 - diaphysis of long bones - pelvis - scapula - ribs

7. What is a very specific test for lupus
Ankylosing spondylitis - uveitis - aortic regurg and bamboo spine
Degenerative injury due to repeated use - tiny tears in the tendons and muscles - may be inflammatory - lateral epicondyle is tennis - medial epicondyle is golf
Myosin light chain phosphotase
Anti ds DNA - poor prognosis

8. What does acantholysis show in pemphigus vulgaris
Macule
Sudden appearance of multiple sebhorrheic keratosis lesions indicating underlying lesions - GI or lymphoid
Osteoarthritis
Intraepidermal bullae involving the skin and oral mucosa

9. What organisms can cause chronic infectious arthritis
TB from dissemination and lyme dz
Parotid enlargement - inc risk of B cell lymphoma - dental caries
Papule
Pseudogout

10. potentially fatal autoimmune disorder with IgG antibody against desmosomes
Embryologic - childbirth defect - cervical rib compression - atrophy of the thenar and hypothenar eminences - atrophy of interosseous muscles - sensory deficits of the medial side of the forearm and hand - disappearance of the radial pulse upon movin
Increase in both osteoblast and osteoclast activity
Gout
Pemphigus vulgaris

11. immune mediated - widespread - non - caseating granulomas - dz - affected population and elevated serum level
Rheumatoid arthritis
Posterior hip dislocation - can't jump - climb stairs or rise from seated positions
SERMs - calcitonin - bisphosphates or pulsatile PTH for severe cases
Sarcoidosis - black females - ACE

12. What are common features of lupus
Pityriasis rosea
Ulnar - opponens digiti minimi - abductor digiti minimi - flexor digiti mimini
Wire - loop lesions in kidney with immune complex deposition - death from renal failure and infxns
Common peroneal - foot eversion and dorsiflexion - toe extention - foot drop - foot slap - stepped gaint - anterolateral leg and dorsal aspect of foot for sensory

13. Contraction results in shortening of what bands - and what band remains the same length
Adduct the fingers
Dorsal side of lateral hand - most of lateral surface of the thumb - no digits
Ulnar
HI shrinks - A stays same

14. What are the lab findings in osteoporosis
Phosphorylated
Nl - decreased bone mass
Osteopetrosis - abnl fxn of osteoclasts
S. aureus - streptococcus

15. What nerve and branch are stretche by subluxation of the radius
Posterior cord
Acanthosis
Deep branch of radial nerve
Abduct the fingers

16. What is the classic presentation of RA
Type 1 - inc mitochondria and myoglobin conc - inc OXPHOS leading to sustained conctraction
EtOH metabolites compete for same excretion site in kidney as uric acid - causing dec uric acid secretion and subsequent buildup
Morning stiffness for > 30 min improving with use - symmetry - systemic sx
Stevens johnson syndrome - associated with adverse drug reactions - more severe version called toxic epidermal necrolysis

17. What disease is caused by autoantibodies to desomosmes - What area of the cell would it occur - and what molecules are connecting
Axillary nerve
Dec estrogen causes inc bone resorption - postmenopausal
Dermatitis herpetiformis
Pemphigus vulgaris - macula adherens where cadherins attach to intermediate filaments

18. Where is C5 dermatome
Iliac crest
S100 - associated with sunligh exposure - fair skinned at risk - depth of tumor correlates with risk of mets - dark with irregular borders
Stevens johnson syndrome - associated with adverse drug reactions - more severe version called toxic epidermal necrolysis
Outer arm

19. What nerve become injured in the incorrect use of a crutch
Polymyaglia rheumatica associated with temporal (giant cell) arteritis
Radial nerve becomes compressed in axilla
Degenerative injury due to repeated use - tiny tears in the tendons and muscles - may be inflammatory - lateral epicondyle is tennis - medial epicondyle is golf
Pseudogout

20. What are the systemic symptoms found in RA
Serum ca - phos - PTH are nl alk phos elevated
Fever - fatigue - pleuritis - pericarditis
Lesioned by midshaft fracture of humerus
Phosphorylated

21. What TX prophylax against osteoporisi
Elevated 1 alpha hydroxylase mediated vit D activation in epithloid macrophages
Exercise and Ca ingestion before age 30
MCP - PIP - no DIP
Upper trunk of brachial plexus

22. What do the lumbrical muscles do
Anti - histone
Inc CK - inc aldolase - and positive ANA and anti Jo -1 - steroids
Flex at the MCP
Verrucae vulgaris

23. larger osteoid osteoma found in vertebral column
Phosphorylated
Osteoblastoma
Lamber eaton - presynaptic Ca channels - dec ACH release leading to proximal muscle weakness
Biceps

24. white painless plaques on the tongue that cannot be scraped off - dz - population - implicated virus
Bullous pemphigoid - linear immunofluorescence - eosinphils within blisters - similar to but less severed thatn pemphigus vulgaris - spares oral mucosa - negaitve nikolsky's sign
Hairy leukoplakia - HIV population - EBV mediated
Sudden appearance of multiple sebhorrheic keratosis lesions indicating underlying lesions - GI or lymphoid
Outer arm

25. What injury causes injury to the MC nerve and what motor and sensory defs dose it cause
Psoriasis
Upper trunk compression - biceps - brachialis - corachobrachialis - flexion of arm at elbow - sensory = lateraly forearm
Head - trunk - extremities - common benign neoplasm in older persons
Radial deviation of wrist upon flexion - ulnar claw hand - pope's blessing

26. In a fracture of the midshaft of the humerus - or extended compression of axilla - nerve - motor - sensory - sign
Radial - BEST extensors - posterior arm and dorsal hand/thumb - wrist drop
Flat bone (skul - facial bones - axial skeleton) woven directly formed - no cartilage - later remodeled to lamellar
Conjunctivitis and anterior uveitis - urethritis and arthritis
Sudden appearance of multiple sebhorrheic keratosis lesions indicating underlying lesions - GI or lymphoid

27. Tumor occuring mostly at epiphyseal end of long bones - occuring btw 20 and 40 - locally aggressive bening tumor around distal femur and proximal tibia - tumor and characteristic xray findings
Radial deviation of wrist upon flexion - ulnar claw hand - pope's blessing
Cervical disk lesion
Giant cell tumor (osteoclastoma) - double bubble or soap bubble
Ulnar deviation - subluxation - bakers cysts (behind knee)

28. pruritic papules and vesicles - deposits of IgA a the tips of dermal papillae - associated with celiac
Dermatitis herpetiformis
Tight jxn - prevents diffusion across paracellular space - composed of claudins and occludins
ANA - sensitive but not specific
Inc alk phos - abnl bone architecture

29. What are predisposing factors for osteosarcoma - xray finding

Warning: Invalid argument supplied for foreach() in /var/www/html/basicversity.com/show_quiz.php on line 183

30. What autoantibodies are formed in sjogrens syndrome
SERMs - calcitonin - bisphosphates or pulsatile PTH for severe cases
Plaque
Ribonucleoprotein antigents - SS- A and SS- B (Ro and La)
Dec estrogen causes inc bone resorption - postmenopausal

31. What nerve controls ab and adduction of the interossei muscles and What does it for the thumb and 4th and 5th lumbricals
Crust
Subclavius
Ulnar nerve - adduction of thumb - extension of 4th and 5th fingers (lumbricals)
Lamber eaton - presynaptic Ca channels - dec ACH release leading to proximal muscle weakness

32. What receptor is constitutively activated in achondroplasia and What does it do
Osteochondroma - exostosis
Embryologic - childbirth defect - cervical rib compression - atrophy of the thenar and hypothenar eminences - atrophy of interosseous muscles - sensory deficits of the medial side of the forearm and hand - disappearance of the radial pulse upon movin
Fibroblast growth factor receptor (FGFR3) inhibits chondrocyte proliferation
Sarcoidosis - black females - ACE

33. What lesion causes claw hand and What are the muscles involved
Vesicle
Median nerve
Ulnar nerve - intrinsic muscles of hand
S. aureus - streptococcus

34. What are the causes of inferior trunk plexus compression and What are the findings
Recurrent branch of the median nerve
Verrucae
Anti ds DNA - poor prognosis
Embryologic - childbirth defect - cervical rib compression - atrophy of the thenar and hypothenar eminences - atrophy of interosseous muscles - sensory deficits of the medial side of the forearm and hand - disappearance of the radial pulse upon movin

35. What are the classic fractures in pts with osteoporosis

Warning: Invalid argument supplied for foreach() in /var/www/html/basicversity.com/show_quiz.php on line 183

36. What are the characterstic joints affected in RA
MCP - PIP - no DIP
Anti - histone
Stevens johnson syndrome - associated with adverse drug reactions - more severe version called toxic epidermal necrolysis
Osteoblastoma

37. herald path followed by days later christmas tree distribution - multiple papular eruptions; remits spontaneously
Subclavius
Macule
Pityriasis rosea
Allopurinaol - uricosurics (probenicid)

38. Where is osteosarcoma found in the bone
Metaphysis of long bones - distal femur
Spindle shaped cells with multinucleated giant cells
Myosin light chain phosphotase
Interossei and adductor policis

39. What do pseudogout crystals appear like microscopically
Basophilic - rhomboid crystals - weakly birefringent
Acanthosis nigcricans
Acantholysis
Scleroderma

40. What are the the common causes of Erb palsy - and What are the associated findings
Serratus anterior - connects scapular to thoracic cage - abduction above horizontal position - injured in mastectomy - winged scapula and lymphedema
Blow to the shoulder - trauma during delivery; limb hangs by side - medially rotated - forearm is pronated
Keloid
Intraepidermal bullae involving the skin and oral mucosa

41. On the palmar side of the hand - what dermatone covers the most of the thumb - 2nd - 3rd - and medial half of the 4th digits and What does it cover on the dorsal side
Crohns and ulcerative colitis
Median nerve - same fingers but not on the hand
Outer arm
Ligand binding leads to muscle depol

42. What lesion causes wrist drop
Lesion to lower trunk of brachial plexus - loss of fxn of all lumbricals - forearm finger flexors - finger extensors are unopposed (radial nerve)
Condyloma acuminatum - caused by HPV
Posterior cord
Loss of medial lumbrical fxn; 4th and 5th digits are clawed - when try to open hand - pinky and ring finger stay clawed

43. What runs the distance of the A band
Myosin
Axilla
Immunoglobulins - malar rash - discoid rash - ANA - mucositis (oropharyngeal ulcers) - neurologic disorders - serositis (pleuritis - pericarditis) - hematologic disorders - arthritis - renal - photosensitivity
Actinic keratosis

44. Which muscle is the pitching injury and What does it do
Ewings sarcoma - aggressive with early mets - but responsive to chemo
Infraspinatus - laterally rotates arm
Blow to the shoulder - trauma during delivery; limb hangs by side - medially rotated - forearm is pronated
Allopurinaol - uricosurics (probenicid)

45. What lesion causes winged scapula
Long thoracic nerve
S. aureus - streptococcus
Inc spinosum - dec granulosum
Ulnar nerve

46. In skeletal and smooth muscle contraction - when Ca2+ enters the cytoplasm - What does it do
In pemphis vulgaris - separation of epidermis upon manual stroking of skin
Polyostotic fibrous dysplasia
Binds troponin C causing a conformational change leading to tropomyosin to move out of the way allowing for actin/myosin cycling
Inc spinosum - dec granulosum

47. bening cartilaginous neoplasm found in intramedullary bone - usually distal extremities
ACH esterase inhibitors - edrophonium test - improvement of sx after edro means the patient is underdosed
Anterior interosseous nerve
Supraspinatus - infraspinatus - teres minor - subscapularis - SItS
Endochondroma

48. What causes osteoporosis type 1 and When does it typically occur
Dec estrogen causes inc bone resorption - postmenopausal
Exercise and Ca ingestion before age 30
Giant cell tumor (osteoclastoma) - double bubble or soap bubble
Parakeratosis

49. Reduction of primarily trabecular (spongy) bone mass despite nl bone mineralization lab values
Myasthenia gravis - autoAb against ACH receptors causing ptosis - diplopia - general weakness -
Proximal median nerve lesion - loss of opponens pollicis muscle fxn leading to unopposoble thumb
Widespread skin involvment - rapid progression - early visceral involvement
Osteoporosis

50. What does PED and Tip stand for

Warning: Invalid argument supplied for foreach() in /var/www/html/basicversity.com/show_quiz.php on line 183