Test your basic knowledge |

Musculoskeletal

Instructions:

Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can study here.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. dried exudates from a vesicle - bulla or pustule seen impetigo
Supraspinatus - infraspinatus - teres minor - subscapularis - SItS
Atopic dermatitis - eczema
Wire - loop lesions in kidney with immune complex deposition - death from renal failure and infxns
Crust

2. What TX prophylax against osteoporisi
Troponin C - conformational change that moves tropomyosin out the myosin binding groove on actin filaments
Sarcoidosis - black females - ACE
Exercise and Ca ingestion before age 30
Precocious puberty

3. Other than characteristic joints and subQ nodules - What are the other findings classicly in RA
Ulnar deviation - subluxation - bakers cysts (behind knee)
Stevens johnson syndrome - associated with adverse drug reactions - more severe version called toxic epidermal necrolysis
Flex at the MCP
Allopurinaol - uricosurics (probenicid)

4. What are the predisposing factors for osteoarthritis
Condyloma acuminatum - caused by HPV
Anti ds DNA - poor prognosis
Conjunctivitis and anterior uveitis - urethritis and arthritis
Age - obesity and joint deformity

5. In smooth muscle contraction - What does Ca bind and What is the purpose
Pagets dz - bone infarcts - radiation - familial retinoblastoma - codman's triangle or sunburst pattern from elevation of periosteum - poor prognsosis
Calmodulin - complex activates myosin light chain kinase
Intraepidermal bullae involving the skin and oral mucosa
Inc Ca - dec phos - inc alk phos - inc PTH - brown tumors

6. What is the precursor to melanom
Osteochondroma - exostosis
Men - needle shaped and negatively birefringent = yellow crystals under parallel light
Femoral - thing flexion and leg extension - anterior thigh and medial leg
Dysplastic nevus

7. What other muscle in the thenar eminence adducts the thumb
EtOH metabolites compete for same excretion site in kidney as uric acid - causing dec uric acid secretion and subsequent buildup
Adductor policis brevis
Axillary nerve
Expansile glistening mass within the medullary cavity

8. What enzyme defect in responsible for osteopetrosis
Gout
Impetigo - s aureus - s pyogenes
Carbonic anhydrase II
HI shrinks - A stays same

9. What is the TX for chronic gout
Peroneal everts and dorsiflexes - foot dropPED; tibial inverts and plantarflexes - can't stand on Tip toes
Allopurinaol - uricosurics (probenicid)
Dec Ca - dec phos - nl alk phos - inc PTH - soft bones
Compressed by cervical rib or pancoasts tumor - leads to klumpke's

10. What does abnl passive abduction of the knee indicate
Supraspinatus - infraspinatus - teres minor - subscapularis - SItS
Torn MCL
Small cell cancer of the lung - improve with muscle use - no change with ACHE inhibs
Osteogenic carcinoma

11. What are the lab findings in pagets disease
Inc alk phos - abnl bone architecture
Subclavius
S. aureus - streptococcus
Dry eyes - dry mouth - nasal and vaginal dryness - chronic bronchitis - reflux esophagitis and No arthritis

12. Warts - soft - tan - colored - cauliflower type lesions - epidermal hyperplasia - hyperkeratosis - koilocytosis
Vitiligo - dec number in melanocytes
Allows adjacent cells to communicate for electric and metabolic fxns - connexons
Melasma (chloasma)
Verrucae

13. common mole - benign
Nevocellular nevus
Polymyaglia rheumatica associated with temporal (giant cell) arteritis
Axilla
Mosiac bone pattern - long bone chalk stick fractures - increased hat size or hearing loss due to auditory foramen narrowing

14. Trauma to lateral aspect of leg or fibula neck fracture - nerve - motor and sens def
Troponin C - conformational change that moves tropomyosin out the myosin binding groove on actin filaments
Common peroneal - foot eversion and dorsiflexion - toe extention - foot drop - foot slap - stepped gaint - anterolateral leg and dorsal aspect of foot for sensory
Tight jxn - prevents diffusion across paracellular space - composed of claudins and occludins
Calmodulin - complex activates myosin light chain kinase

15. 2nd most malignant tumor of bone - men 10-20 - cancer - and primary malignant tumor bone
Anti Smith
Small cell cancer of the lung - improve with muscle use - no change with ACHE inhibs
Osteosarcoma - multiple myeloma
Long thoracic nerve

16. What are the lab findings in osteomalacia/rickets
Anterior interosseous nerve
Inc spinosum - dec granulosum
Myosin releases bound ADP and is displaced on the actin filament
Dec Ca - dec phos - nl alk phos - inc PTH - soft bones

17. yellow when parallel and blue when perpendicular
Gout
Intermediate jxn - just below zona occludens - cadherins and actin filaments - cadherins are dependent on Ca2+
Recurrent branch of the median nerve
Deep branch of radial nerve

18. What does lack of ATP cause
Anti ds DNA - poor prognosis
Rigor mortis
Upper trunk of brachial plexus
SERMs - calcitonin - bisphosphates or pulsatile PTH for severe cases

19. What are predisposing factors for osteosarcoma - xray finding

Warning: Invalid argument supplied for foreach() in /var/www/html/basicversity.com/show_quiz.php on line 183

20. What is the defect in Paget's disease
Phosphorylates myosin light chain which leads to cross bridge formation
Serum ca - phos - PTH are nl alk phos elevated
Polyostotic fibrous dysplasia
Increase in both osteoblast and osteoclast activity

21. What are the common perpetrating infections for Reiters syndrome
Post GI infxn or chlamydia
Dec Ca - dec phos - nl alk phos - inc PTH - soft bones
Anti - CCP - HLA- DR4
Mosiac bone pattern - long bone chalk stick fractures - increased hat size or hearing loss due to auditory foramen narrowing

22. What are the layers of of the epidermis from surface to base
Ulnar nerve
Osteochondroma - exostosis
Corneum - lucidum - granulosum - spinosum - basalis
Calmodulin - complex activates myosin light chain kinase

23. What antibody is less sensitive than RF but more specific and What is the HLA association
Musculocutaneous
Vit D def - dec Ca - inc PTH - dec serum phos - reversible when vit D is replaced
Anti - CCP - HLA- DR4
Chondrosarcoma

24. heliotrope rash 'shawl and face' rash - Gotton's papules - 'mechanic's hands'
Cellulitis - s aureus - s pyogenes
Polymyositis - shoulders - perifasicular inflammation
Dermatomyositis
Ulnar

25. immune mediated - widespread - non - caseating granulomas - dz - affected population and elevated serum level
Lesioned by midshaft fracture of humerus
Sarcoidosis - black females - ACE
Parotid enlargement - inc risk of B cell lymphoma - dental caries
Tight jxn - prevents diffusion across paracellular space - composed of claudins and occludins

26. What does ATP do in skeletal muscle contraction
Binds myosin head and releases actin filament allowing cross - bridge cycling and shortening to occur
Men and women > 70 - senile osteporosis
Nl - decreased bone mass
NSAIDs (indomethacin) colchicine

27. What nerve is injured by a superficial laceration of the hand
Recurrent branch of the medain nerve
Proximal median nerve lesion - loss of opponens pollicis muscle fxn leading to unopposoble thumb
Condyloma acuminatum - caused by HPV
Osteogenic carcinoma

28. Ca2+ released from the SR binds what structure and What does it cause
Troponin C - conformational change that moves tropomyosin out the myosin binding groove on actin filaments
Pemphigus vulgaris
Elevated ESR and nl CK - prednisone
Radial nerve

29. What causes heart failure in with Paget's disease
Lichen planus
Adductor policis brevis
Cervical disk lesion
Inc blood flow from AV shunts can cause high output heart failure

30. What are the lab findings in osteoporosis
Acantholysis
Nl - decreased bone mass
Middle bicep down - cuts lateral at cuboidal foass and runs distally to include the thumb and 2nd digit
Elevated 1 alpha hydroxylase mediated vit D activation in epithloid macrophages

31. What are the borders of the superficial branch of the radial nerve dermatone
ACH esterase inhibitors - edrophonium test - improvement of sx after edro means the patient is underdosed
Median nerve
Dorsal side of lateral hand - most of lateral surface of the thumb - no digits
Median nerve - lunate bone

32. potentially fatal autoimmune disorder with IgG antibody against desmosomes
Pemphigus vulgaris
Opposition of thumb - dorsal/palmar 3.5 fingers sensory - ulnar deviation upon wrist flexion
Lamber eaton - presynaptic Ca channels - dec ACH release leading to proximal muscle weakness
Infraspinatus - laterally rotates arm

33. inflammatory disorder affective synovial joints with pannus formation in joints
Pustule
Type 2
Rheumatoid arthritis
Erythema multiforme - can be macules - papules vesicles - target lesions -

34. When does membranous ossification occur and What is the difference between membranous and endochondrial
Flat bone (skul - facial bones - axial skeleton) woven directly formed - no cartilage - later remodeled to lamellar
Radial nerve becomes compressed in axilla
NC migration
Acanthosis nigcricans

35. What causes hypercalcemia in pts with sarcoid
Ulnar nerve - fracture of hook of hamate
Osteoma (gardners syndrome) - new piece of bone grows on another bone - often skull
Elevated 1 alpha hydroxylase mediated vit D activation in epithloid macrophages
Infraspinatus - laterally rotates arm

36. What is the power stroke of muscle contraction
Interossei and adductor policis
Myosin releases bound ADP and is displaced on the actin filament
Adductor policis brevis
Ulnar nerve - fracture of hook of hamate

37. What molecule maintatins integrity of basement membrane and What does it bind
Anti - CCP - HLA- DR4
Onion skin - 11:22 - diaphysis of long bones - pelvis - scapula - ribs
Integrin binds laminin in BM
Allows adjacent cells to communicate for electric and metabolic fxns - connexons

38. What are characteristic findings of gout
Asymmetric - swollen - red - painful joint - often MTP (podagra) - tophus formation on external ear - olecranon bursa - achilles tendon
85% - advanced paternal age - or auto dominant inheritance
Erythema nodosum
Stevens johnson syndrome - associated with adverse drug reactions - more severe version called toxic epidermal necrolysis

39. What happens in the power stroke of skeletal muscle contraction
Phosphate is liberated from the myosin head
Stevens johnson syndrome - associated with adverse drug reactions - more severe version called toxic epidermal necrolysis
Axilla
Binds troponin C causing a conformational change leading to tropomyosin to move out of the way allowing for actin/myosin cycling

40. interlacing trabeculae of woven bone surrounded by osteoblasts
Osteoid osteoma
Post GI infxn or chlamydia
Axilla
Failure of longitudinal growth (endochondrial ossification) leading to short limbs - membranous is unaffected - large head

41. What is the classic presentation of osteoarthritis
Integrin binds laminin in BM
Pain in weight bearing joints at the end of the day and improving with rest
Type 2 - dec mitochondria and myoglobin - inc anaerobic glycolysis
Schaumann (calcium and protein inclusions inside Langhans giant cells) and asteroid bodies

42. inc thickness of stratum corneum seen in psoriasis
Boutonniere - swan neck - zthumb
Hyperkeratosis
Wire - loop lesions in kidney with immune complex deposition - death from renal failure and infxns
Tight jxn - prevents diffusion across paracellular space - composed of claudins and occludins

43. On the palmar and dorsal sides of the hand - what dermatome covers the 5th finger and the lateral 1/2 of the 4th finger
Ulnar
GC and cGMP and inhibition of MLCK
Anti - histone
Tibial - foot inversioon and plantarflexion; toe flexion - sole of foot is sensory

44. What runs the distance of the A band
Psoriasis
Myosin
Palisading
Anti - histone

45. Macule greater than 1cm
Patch
Carbonic anhydrase II
Medial 1.5 fingers - hypothenar eminence
Pemphigus vulgaris

46. What are the lab findings and TX in dermatomyositis
Middle bicep down - cuts lateral at cuboidal foass and runs distally to include the thumb and 2nd digit
Inc CK - inc aldolase - and positive ANA and anti Jo -1 - steroids
Palisading
Carbonic anhydrase II

47. What are the bone mineralization lab findings in osteopetrosis
Polymyaglia rheumatica associated with temporal (giant cell) arteritis
Serum ca - phos - alk phos are NL
Acanthosis nigcricans
Atopic dermatitis - eczema

48. What is the classic presentation of RA
Morning stiffness for > 30 min improving with use - symmetry - systemic sx
Medial forearm and arm to just under the axilla
Urticaria
Pustule

49. What form of polyostotic fibrous dysplasia has multiple unilateral bones lesions associated with endocrine abnl and unilateral pigmented skin lesions - caf
Men and women > 70 - senile osteporosis
Serum ca - phos - alk phos are NL
McCune - Albright syndrome
Medial finger flexion - wrist flexion

50. small fluid containing blister seen in chickenpox
Vesicle
Renal - pulm - CV - GI - 75% female
Strawberry hemangioma
Sudden appearance of multiple sebhorrheic keratosis lesions indicating underlying lesions - GI or lymphoid

Sorry!:) No result found.

Can you answer 50 questions in 15 minutes?

Major Subjects
Tests & Exams AP CLEP DSST GRE SAT GMAT	Certifications CISSP go to https://www.isc2.org/ PMP ITIL RHCE MCTS More...	IT Skills Android Programming Data Modeling Objective C Programming Basic Python Programming Adobe Illustrator More...	Business Skills Advertising Techniques Business Accounting Basics Business Strategy Human Resource Management Marketing Basics More...
Soft Skills Body Language People Skills Public Speaking Persuasion Job Hunting And Resumes More...	Vocabulary GRE Vocab SAT Vocab TOEFL Essential Vocab Basic English Words For All Global Words You Should Know Business English More...	Languages AP German Vocab AP Latin Vocab SAT Subject Test: French Italian Survival Norwegian Survival More...	Engineering Audio Engineering Computer Science Engineering Aerospace Engineering Chemical Engineering Structural Engineering More...
Health Sciences Basic Nursing Skills Health Science Language Fundamentals Veterinary Technology Medical Language Cardiology Clinical Surgery More...	English Grammar Fundamentals Literary And Rhetorical Vocab Elements Of Style Vocab Introduction To English Major Complete Advanced Sentences Literature Homonyms More...	Math Algebra Formulas Basic Arithmetic: Measurements Metric Conversions Geometric Properties Important Math Facts Number Sense Vocab Business Math More...	Other Major Subjects Science Economics History Law Performing-arts Cooking Logic & Reasoning Trivia

Test your basic knowledge |

Musculoskeletal

Sorry!:) No result found.

Can you answer 50 questions in 15 minutes?

Let me suggest you:

Browse all subjects

Browse all tests

Most popular tests

Major Subjects

Tests & Exams

Certifications

IT Skills

Business Skills

Soft Skills

Vocabulary

Languages

Engineering

Health Sciences

English

Math

Other Major Subjects

Browse all subjects

Browse all tests

Most popular tests