Test your basic knowledge |

Musculoskeletal

Instructions:

Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can study here.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. What does injury to the distal median nerve cause

Warning: Invalid argument supplied for foreach() in /var/www/html/basicversity.com/show_quiz.php on line 183

2. What organisms can cause chronic infectious arthritis
Stevens johnson syndrome - associated with adverse drug reactions - more severe version called toxic epidermal necrolysis
Ulnar - opponens digiti minimi - abductor digiti minimi - flexor digiti mimini
TB from dissemination and lyme dz
Actinic keratosis - risk proportional to epithelial dysplasia

3. Which muscle is the pitching injury and What does it do
Wheal
False positives on syphillis test (RPR/VRDL) due to antiphospholipid antibodies - cross react with cardiolipin
Infraspinatus - laterally rotates arm
Men - needle shaped and negatively birefringent = yellow crystals under parallel light

4. subchondreal cysts - sclerosis - osteophytes - joint space narrowing - eburnation - hebereden's nodes (DIP) bouchard nodes (PIP) - characteristic findings of this dz
Outer arm
Fever - fatigue - pleuritis - pericarditis
Osteoarthritis
Papule

5. pelvic fracture can cause injury to which nerve - and What are the motor and sens def
Cellulitis - s aureus - s pyogenes
Paralysis of lateral rotators
Failure of longitudinal growth (endochondrial ossification) leading to short limbs - membranous is unaffected - large head
Femoral - thing flexion and leg extension - anterior thigh and medial leg

6. What are the characterstic joints affected in RA
MCP - PIP - no DIP
Allopurinaol - uricosurics (probenicid)
SERMs - calcitonin - bisphosphates or pulsatile PTH for severe cases
Post GI infxn or chlamydia

7. What is the Auspitz sign
Opposition of thumb - dorsal/palmar 3.5 fingers sensory - ulnar deviation upon wrist flexion
Antibodies around cells of the epidermis in a reticular or netlike pattern
Myosin light chain phosphotase
In psoriasis - bleeding spots when scales are scraped off

8. Macule greater than 1cm
Tight jxn - prevents diffusion across paracellular space - composed of claudins and occludins
Patch
Ischial spine - relieve pain during delivery
Outer arm

9. What is the primary screening test for lupus
ANA - sensitive but not specific
Chondrosarcoma - pelvis - spine - scapula - humerus - tibia - or femur
EtOH metabolites compete for same excretion site in kidney as uric acid - causing dec uric acid secretion and subsequent buildup
Plaque

10. What is the landmark for an LP
Paralysis of abductors
Iliac crest
Thymoma
Hands and face - ulcerative red lesion - locally invasive bur rare metastasis - associated with chronic draining sinuses and keratin pearls

11. What do the lumbrical muscles do
Scleroderma
Flex at the MCP
Anti Smith
ACH esterase inhibitors - edrophonium test - improvement of sx after edro means the patient is underdosed

12. What are the the common causes of Erb palsy - and What are the associated findings
Degenerative injury due to repeated use - tiny tears in the tendons and muscles - may be inflammatory - lateral epicondyle is tennis - medial epicondyle is golf
Blow to the shoulder - trauma during delivery; limb hangs by side - medially rotated - forearm is pronated
Elevated 1 alpha hydroxylase mediated vit D activation in epithloid macrophages
Allopurinaol - uricosurics (probenicid)

13. freckle - normal number of melanocytes - inc melanin pigment
Immunoglobulins - malar rash - discoid rash - ANA - mucositis (oropharyngeal ulcers) - neurologic disorders - serositis (pleuritis - pericarditis) - hematologic disorders - arthritis - renal - photosensitivity
Compressed by cervical rib or pancoasts tumor - leads to klumpke's
Serum ca - phos - alk phos are NL
Ephelis

14. What is the power stroke of muscle contraction
Boutonniere - swan neck - zthumb
S. aureus - streptococcus
Myosin releases bound ADP and is displaced on the actin filament
Medial aspect

15. Associated with M. pneumonia - HSV - sulfa drugs - B lactams - phenytoin - cancers and autoimmune dz - skin disorder and description
Vitiligo - dec number in melanocytes
Ulnar
Erythema multiforme - can be macules - papules vesicles - target lesions -
Blow to the shoulder - trauma during delivery; limb hangs by side - medially rotated - forearm is pronated

16. What are the lab findings and TX in dermatomyositis
Inc CK - inc aldolase - and positive ANA and anti Jo -1 - steroids
Hairy leukoplakia - HIV population - EBV mediated
Dermatitis herpetiformis
Ulnar nerve - fracture of hook of hamate

17. white painless plaques on the tongue that cannot be scraped off - dz - population - implicated virus
Xeropthalmia - xerostomia - arthritis
Pustule
Hairy leukoplakia - HIV population - EBV mediated
Anti - histone

18. dried exudates from a vesicle - bulla or pustule seen impetigo
Crust
Erythema multiforme - can be macules - papules vesicles - target lesions -
Corneum - lucidum - granulosum - spinosum - basalis
GC and cGMP and inhibition of MLCK

19. Administration of what kind of compound causes reversal of symptoms and What is used to distringuish under from over dosing
Tibial - foot inversioon and plantarflexion; toe flexion - sole of foot is sensory
ACH esterase inhibitors - edrophonium test - improvement of sx after edro means the patient is underdosed
Hyperkeratosis
Osteoporosis

20. locally invasive but rarely mets skin cancer - rolled edges - with central ulceration - cancer and gross path
EtOH metabolites compete for same excretion site in kidney as uric acid - causing dec uric acid secretion and subsequent buildup
Basal cell carcinoma - pearly papules - commonly with telangiectasias
Wire - loop lesions in kidney with immune complex deposition - death from renal failure and infxns
Pemphigus vulgaris

21. mechanical wear and tear of joints leading to destruction of articular cartilage
Osteopetrosis - abnl fxn of osteoclasts
Vit D def - dec Ca - inc PTH - dec serum phos - reversible when vit D is replaced
Anemia - thrombocytopenia - infection - extramedullary hematopoiesis
Osteoarthritis

22. What do palmar interosseous muscles do
Widespread skin involvment - rapid progression - early visceral involvement
Adduct the fingers
Calmodulin - complex activates myosin light chain kinase
Proximal median nerve lesion - loss of opponens pollicis muscle fxn leading to unopposoble thumb

23. What causes ape hand
Dec estrogen causes inc bone resorption - postmenopausal
Proximal median nerve lesion - loss of opponens pollicis muscle fxn leading to unopposoble thumb
Osteoarthritis
Median nerve - lunate bone

24. What is the test for drug induced lupus
McCune - Albright syndrome
Anti - histone
Cherry hemangioma
Infraspinatus - laterally rotates arm

25. What autoantibodies are formed in sjogrens syndrome
Ribonucleoprotein antigents - SS- A and SS- B (Ro and La)
Ulnar deviation - subluxation - bakers cysts (behind knee)
Actinic keratosis
Mosiac bone pattern - long bone chalk stick fractures - increased hat size or hearing loss due to auditory foramen narrowing

26. What variant of squamous cells carcinoma of the skin grows rapidly and regresses spontaneously
Loss of medial lumbrical fxn; 4th and 5th digits are clawed - when try to open hand - pinky and ring finger stay clawed
Recurrent branch of the medain nerve
In pemphis vulgaris - separation of epidermis upon manual stroking of skin
Keratoacanthoma

27. Where is C4 dermatome
MCL - ACL - lateral meniscus (esp in athletes)
Over deltoid
Myosin
In pemphis vulgaris - separation of epidermis upon manual stroking of skin

28. What is the clinically important landmark for pubendal nerve block and When is it used
Fibrinoid necrosis surrounded by palisading histiocytes
Adductor policis brevis
Necrotizing fasciitis - anaerobic bacteria or S. pyogenes
Ischial spine - relieve pain during delivery

29. What is the source of osteoblast cells
Ribonucleoprotein antigents - SS- A and SS- B (Ro and La)
Muslce use - nerve stim/compound muscle test
Mesenchymal stem cells in periosteum
Head - trunk - extremities - common benign neoplasm in older persons

30. What nerve become injured in the incorrect use of a crutch
Verrucae
Tear of the ACL
Radial nerve becomes compressed in axilla
In pemphis vulgaris - separation of epidermis upon manual stroking of skin

31. What are the lab findings in osteopetrosis
Peroneal everts and dorsiflexes - foot dropPED; tibial inverts and plantarflexes - can't stand on Tip toes
Chondrosarcoma
Nl - thickened dense bones
Loss of lateral lumbrical fxn - 2nd and 3d digits are clawed and can't extend

32. what changes are seen in stratum spinosum and granulosum in psoriasis
Recurrent branch of the median nerve
Inc spinosum - dec granulosum
Osteopetrosis - abnl fxn of osteoclasts
Corneum - lucidum - granulosum - spinosum - basalis

33. What antibodies is diffuse scleroderma associated with
Patch
Anti Scl70 - anti DNA topoisomerase I antibody
Melasma (chloasma)
In pemphis vulgaris - separation of epidermis upon manual stroking of skin

34. What kind of nuclei do basal cell tumors have
3rd finger
Opposition of thumb - dorsal/palmar 3.5 fingers sensory - ulnar deviation upon wrist flexion
Dermatitis herpetiformis
Palisading

35. What does subscapularis do
Inc Ca - dec phos - inc alk phos - inc PTH - brown tumors
Pityriasis rosea
Seborrheic keratosis
Medially rotates and adducts arm

36. In which joints does pseudogout typically occur
Pain in weight bearing joints at the end of the day and improving with rest
Sites of tibial attachment
Large goints (knee)
Anti ds DNA - poor prognosis

37. How is chondrosarcoma described
Expansile glistening mass within the medullary cavity
Rigor mortis
Dysplastic nevus
Acute back pain - loss of height - and kyphosis

38. What does injury to the distal ulnar nerve cause
Loss of lateral lumbrical fxn - 2nd and 3d digits are clawed and can't extend
Loss of medial lumbrical fxn; 4th and 5th digits are clawed - when try to open hand - pinky and ring finger stay clawed
EtOH metabolites compete for same excretion site in kidney as uric acid - causing dec uric acid secretion and subsequent buildup
Radial nerve

39. What kind of jxn is the zona occludens andw What is is composed of...
Boutonniere - swan neck - zthumb
MCL - ACL - lateral meniscus (esp in athletes)
Tight jxn - prevents diffusion across paracellular space - composed of claudins and occludins
Cartilaginous by chondrocytes first - osteoclasts and osteoblasts later replace with women bone and remodel to lamellar bone - endochondrial ossification

40. Tumor occuring mostly at epiphyseal end of long bones - occuring btw 20 and 40 - locally aggressive bening tumor around distal femur and proximal tibia - tumor and characteristic xray findings
Impetigo - s aureus - s pyogenes
Giant cell tumor (osteoclastoma) - double bubble or soap bubble
Rheumatoid arthritis
Morning stiffness for > 30 min improving with use - symmetry - systemic sx

41. What causes the symptoms of MG to worsen - and What is used to diagnose
Muslce use - nerve stim/compound muscle test
Gout
Trauma
Pityriasis rosea

42. dactylitis and pencil in cup deformity on xray - patchy skin rash and joint pain
Lower trunk of brachial plexus
Metaphysis of long bones - distal femur
Fracture of surgical neck - dislocation of the humerus - intramuscular injections
Psoriatic arthritis - occurs is less than 1/3 of psoriasis pts

43. Where is C6 dermatome
Type 2 - dec mitochondria and myoglobin - inc anaerobic glycolysis
Middle bicep down - cuts lateral at cuboidal foass and runs distally to include the thumb and 2nd digit
Medially rotates and adducts arm
Parotid enlargement - inc risk of B cell lymphoma - dental caries

44. Very superfiicial skin infection - honey colored crusting - very contagious - condition and organisms
Impetigo - s aureus - s pyogenes
Ribonucleoprotein antigents - SS- A and SS- B (Ro and La)
Actinic keratosis
Cartilaginous by chondrocytes first - osteoclasts and osteoblasts later replace with women bone and remodel to lamellar bone - endochondrial ossification

45. What are the borders of the superficial branch of the radial nerve dermatone
Dorsal side of lateral hand - most of lateral surface of the thumb - no digits
Inc CK - inc aldolase - and positive ANA and anti Jo -1 - steroids
Keratoacanthoma
Type 1 - inc mitochondria and myoglobin conc - inc OXPHOS leading to sustained conctraction

46. In which gender is gout more common and What does the crystals appear like microscopically
Voltage sens - dihydropiridine R coupled to ryanodine recpetor - conformational change in the SR - releasing Ca2+
Medially rotates and adducts arm
Men - needle shaped and negatively birefringent = yellow crystals under parallel light
Fibrinoid necrosis surrounded by palisading histiocytes

47. In a fracture of the midshaft of the humerus - or extended compression of axilla - nerve - motor - sensory - sign
Hyperkeratosis
Loss of medial lumbrical fxn; 4th and 5th digits are clawed - when try to open hand - pinky and ring finger stay clawed
STD presents as a monarticular - migratory arthritis with an asynmetrical pattern - affected joint is painful - red and swollen
Radial - BEST extensors - posterior arm and dorsal hand/thumb - wrist drop

48. irregular raised lesion resulting from scar tissue hypertrophy - follows trauma to skin - common to african americans see in T. pertenue (yaws)
Rigor mortis
Keloid
Ankylosing spondylitis - uveitis - aortic regurg and bamboo spine
Wheal

49. What muscles of the shoulder form the rotator cuff
Supraspinatus - infraspinatus - teres minor - subscapularis - SItS
Ischial spine - relieve pain during delivery
Vertebral crush fractures - femoral neck fractures - distal radius (Colles') fracture
Muslce use - nerve stim/compound muscle test

50. chronic inflammatory disease of sacroiliac joints and spine - dz - associations
Voltage sens - dihydropiridine R coupled to ryanodine recpetor - conformational change in the SR - releasing Ca2+
Ankylosing spondylitis - uveitis - aortic regurg and bamboo spine
Acanthosis
Phosphorylated