Test your basic knowledge |

Musculoskeletal

Instructions:

Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can study here.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. 2nd most malignant tumor of bone - men 10-20 - cancer - and primary malignant tumor bone
HI shrinks - A stays same
Osteosarcoma - multiple myeloma
Axillary - deltoid - skin over deltoid - flattened deltoid
Necrotizing fasciitis - anaerobic bacteria or S. pyogenes

2. How is diffuse scleroderma characterized
Medial 1.5 fingers - hypothenar eminence
Blow to the shoulder - trauma during delivery; limb hangs by side - medially rotated - forearm is pronated
Osteoid osteoma
Widespread skin involvment - rapid progression - early visceral involvement

3. papules and plaques with silvery scaling - especially on knees and elbows - acanthosis with parakeratotic scaling (nuclei sill in stratun corneum - nail pitting and arthritis
Schaumann (calcium and protein inclusions inside Langhans giant cells) and asteroid bodies
B27 - no RF - males
Musculocutaneous
Psoriasis

4. What does abnl passive abduction of the knee indicate
Torn MCL
Lung
Rigor mortis
Allows adjacent cells to communicate for electric and metabolic fxns - connexons

5. large fluid containing blisters seen in bullous pemphigoid
Tear of the ACL
Tight jxn - prevents diffusion across paracellular space - composed of claudins and occludins
Bulla
Osteoma (gardners syndrome) - new piece of bone grows on another bone - often skull

6. anaplastic small blue cell malignant tumor - most common in boys < 15 - dz and prognosis
Dorsal side of lateral hand - most of lateral surface of the thumb - no digits
Ulnar nerve
Psoriatic arthritis - occurs is less than 1/3 of psoriasis pts
Ewings sarcoma - aggressive with early mets - but responsive to chemo

7. What is the TX for acute gout
NSAIDs (indomethacin) colchicine
Necrotizing fasciitis - anaerobic bacteria or S. pyogenes
Median nerve
Ribonucleoprotein antigents - SS- A and SS- B (Ro and La)

8. IBS - 2 dz's
Osteogenic carcinoma
Crohns and ulcerative colitis
Phosphorylated
Precocious puberty

9. which muscle type is fast twitch and why are fibers white
STD presents as a monarticular - migratory arthritis with an asynmetrical pattern - affected joint is painful - red and swollen
Type 2 - dec mitochondria and myoglobin - inc anaerobic glycolysis
Fracture of surgical neck - dislocation of the humerus - intramuscular injections
Ulnar nerve - fracture of hook of hamate

10. What is a very specific test for lupus
Anti ds DNA - poor prognosis
S. aureus - streptococcus
Opposition of thumb - dorsal/palmar 3.5 fingers sensory - ulnar deviation upon wrist flexion
Conjunctivitis and anterior uveitis - urethritis and arthritis

11. What nerve controls ab and adduction of the interossei muscles and What does it for the thumb and 4th and 5th lumbricals
Paralysis of abductors
Ulnar nerve - adduction of thumb - extension of 4th and 5th fingers (lumbricals)
Medial forearm and arm to just under the axilla
Median nerve - same fingers but not on the hand

12. Where are most osteoid osteoma found and In what population
Pityriasis rosea
< 2mc found in proximal tibia and femur - men < 25
Rheumatoid arthritis
Dermatomyositis

13. What nerve is compressed by supracondylar fracture of humerus
Median nerve
Median - lateral finger and wrist flexion - dorsal palmar aspects of lateral 3.5 fingers/thenar eminence - ape hand - carpal tunnel syndrome
Outer arm
Men - needle shaped and negatively birefringent = yellow crystals under parallel light

14. potentially fatal autoimmune disorder with IgG antibody against desmosomes
Hyperkeratosis
Actinic keratosis
Pemphigus vulgaris
Serum ca - phos - PTH are nl alk phos elevated

15. Which nerve is compressed in deep forearm
Anterior interosseous nerve
Chondrosarcoma
Anti - histone
Lower trunk of brachial plexus

16. What are defining lab findings for polymyalgia rheumatica and What is the TX
Osteochondroma - exostosis
Dermatitis herpetiformis
Pseudogout
Elevated ESR and nl CK - prednisone

17. What are the characteristic bone findings in paget's disease
Long thoracic nerve
Mosiac bone pattern - long bone chalk stick fractures - increased hat size or hearing loss due to auditory foramen narrowing
Nl - thickened dense bones
McCune - Albright syndrome

18. What are the bone mineralization lab findings in osteopetrosis
Serum ca - phos - alk phos are NL
Condyloma acuminatum - caused by HPV
Chondrosarcoma
Median - opponens pollicis - abductors pollicis brevis - flexor pollicis brevis

19. freckle - normal number of melanocytes - inc melanin pigment
Defective mineralization/calcification of osteoid - osteomalacia in adults and ricketts in kids
Phosphorylated
Axillary nerve
Ephelis

20. What are the lab findings in osteomalacia/rickets
Palisading
Dec Ca - dec phos - nl alk phos - inc PTH - soft bones
HI shrinks - A stays same
Chondrosarcoma - pelvis - spine - scapula - humerus - tibia - or femur

21. papule > 1cm seen psoriasis
Fever - fatigue - weight loss - nonbacterial verruucous (Liebman - Sacks) endocarditis - hilar adenopathy - Raynauds
Subclavius
Plaque
Loss of medial lumbrical fxn; 4th and 5th digits are clawed - when try to open hand - pinky and ring finger stay clawed

22. What disease is caused by autoantibodies to desomosmes - What area of the cell would it occur - and what molecules are connecting
Pemphigus vulgaris - macula adherens where cadherins attach to intermediate filaments
Chondrosarcoma - pelvis - spine - scapula - humerus - tibia - or femur
Osteosarcoma - multiple myeloma
Axillary nerve

23. What does soft bones result from and What is the dz called in adults and children
Long thoracic nerve
Squamous cell carcinoma
Cervical disk lesion
Defective mineralization/calcification of osteoid - osteomalacia in adults and ricketts in kids

24. knee trauma - nerve - motor and sensory def
Axilla
Tibial - foot inversioon and plantarflexion; toe flexion - sole of foot is sensory
Defective mineralization/calcification of osteoid - osteomalacia in adults and ricketts in kids
Head - trunk - extremities - common benign neoplasm in older persons

25. loss of what muscles in Erbs causes the medial rotation
Median nerve - lunate bone
Xeropthalmia - xerostomia - arthritis
Macule
Paralysis of lateral rotators

26. In which form is myosin light chain active
Trauma
Phosphorylated
Parotid enlargement - inc risk of B cell lymphoma - dental caries
Median nerve

27. skin cancer associatd associated with excessive exposure to sunlight and arsenic
Proximal median nerve lesion - loss of opponens pollicis muscle fxn leading to unopposoble thumb
Squamous cell carcinoma
Superior glut - thigh abduction - pos trendelenburg - hip drops when standing on the opposite foot (standing on the side of the lesion)
Subclavius

28. What molecule maintatins integrity of basement membrane and What does it bind
Dorsal side of lateral hand - most of lateral surface of the thumb - no digits
ANA - sensitive but not specific
Cherry hemangioma
Integrin binds laminin in BM

29. What are the subQ rheumatoid nodules made of...
Anti Scl70 - anti DNA topoisomerase I antibody
Fibrinoid necrosis surrounded by palisading histiocytes
Radial deviation of wrist upon flexion - ulnar claw hand - pope's blessing
Fever - fatigue - weight loss - nonbacterial verruucous (Liebman - Sacks) endocarditis - hilar adenopathy - Raynauds

30. What are the motor - sensory deficits and sign of carpal tunnel syndrome
Myasthenia gravis - autoAb against ACH receptors causing ptosis - diplopia - general weakness -
Opposition of thumb - dorsal/palmar 3.5 fingers sensory - ulnar deviation upon wrist flexion
Men - needle shaped and negatively birefringent = yellow crystals under parallel light
Middle bicep down - cuts lateral at cuboidal foass and runs distally to include the thumb and 2nd digit

31. hyperkeratosis with retention of nuclei in stratum corneum seen in psoriasis
Bulla
Elevated 1 alpha hydroxylase mediated vit D activation in epithloid macrophages
Parakeratosis
Radial - BEST extensors - posterior arm and dorsal hand/thumb - wrist drop

32. What lesion causes winged scapula
Long thoracic nerve
Lesioned by midshaft fracture of humerus
Restrictive lung disease - bilateral hilar lymphadenopathy - erythema nodosum - Bell's palsy
Atopic dermatitis - eczema

33. Patients with pagets disease can develop what cancer
Immunoglobulins - malar rash - discoid rash - ANA - mucositis (oropharyngeal ulcers) - neurologic disorders - serositis (pleuritis - pericarditis) - hematologic disorders - arthritis - renal - photosensitivity
Bullous pemphigoid - linear immunofluorescence - eosinphils within blisters - similar to but less severed thatn pemphigus vulgaris - spares oral mucosa - negaitve nikolsky's sign
Osteogenic carcinoma
3rd finger

34. How is the lower trunk of the brachia plexus injured and what results from it

Warning: Invalid argument supplied for foreach() in /var/www/html/basicversity.com/show_quiz.php on line 183

35. separation of epidermal cells
MCL - ACL - lateral meniscus (esp in athletes)
Acantholysis
Spindle shaped cells with multinucleated giant cells
Anti ds DNA - poor prognosis

36. Damage to what 3 structures is common for the unhappy triad
MCL - ACL - lateral meniscus (esp in athletes)
4th and 5th finger
Ligand binding leads to muscle depol
Spindle shaped cells with multinucleated giant cells

37. What are the characterstic joints affected in RA
Blow to the shoulder - trauma during delivery; limb hangs by side - medially rotated - forearm is pronated
MCP - PIP - no DIP
Ulnar
Polyostotic fibrous dysplasia

38. What are the lab findings in osteoporosis
Anti Scl70 - anti DNA topoisomerase I antibody
Nl - decreased bone mass
Paralysis of abductors
Osteogenic carcinoma

39. What kind of nuclei do basal cell tumors have
Median - lateral finger and wrist flexion - dorsal palmar aspects of lateral 3.5 fingers/thenar eminence - ape hand - carpal tunnel syndrome
Blow to the shoulder - trauma during delivery; limb hangs by side - medially rotated - forearm is pronated
Palisading
Mesenchymal stem cells in periosteum

40. How does gonococcal arthritis present
Necrotizing fasciitis - anaerobic bacteria or S. pyogenes
STD presents as a monarticular - migratory arthritis with an asynmetrical pattern - affected joint is painful - red and swollen
Biceps
Carbonic anhydrase II

41. Other than characteristic joints and subQ nodules - What are the other findings classicly in RA
Dorsal side of lateral hand - most of lateral surface of the thumb - no digits
Pseudogout
Polymyositis - shoulders - perifasicular inflammation
Ulnar deviation - subluxation - bakers cysts (behind knee)

42. What cancer in particular are associated with LE syndrome - what happens to symptoms with muscle use or ACH esterase inhibs
Flat bone (skul - facial bones - axial skeleton) woven directly formed - no cartilage - later remodeled to lamellar
Steroids
Glucocorticoids
Small cell cancer of the lung - improve with muscle use - no change with ACHE inhibs

43. What is the source of osteoblast cells
Mesenchymal stem cells in periosteum
Elevated ESR and nl CK - prednisone
Gout
Widespread skin involvment - rapid progression - early visceral involvement

44. What lesion causes Saturday night wrist drop
Median - opponens pollicis - abductors pollicis brevis - flexor pollicis brevis
Radial nerve
Compressed by cervical rib or pancoasts tumor - leads to klumpke's
Calcinosis - raynauds - esophageal dysmotility - sclerodactyly - telangiectasia - anti centromere antibody

45. acute painful spreading infxn of dermis and subQ tissues - condition and orgs
Interossei and adductor policis
Serratus anterior - connects scapular to thoracic cage - abduction above horizontal position - injured in mastectomy - winged scapula and lymphedema
Cellulitis - s aureus - s pyogenes
Osteochondroma - exostosis

46. What is the defect in Paget's disease
Fever - fatigue - weight loss - nonbacterial verruucous (Liebman - Sacks) endocarditis - hilar adenopathy - Raynauds
Teres minor
Increase in both osteoblast and osteoclast activity
Over deltoid

47. What does the positive anterior drawer sign test indicate
Tear of the ACL
Ischial spine - relieve pain during delivery
Proximal median nerve lesion - loss of opponens pollicis muscle fxn leading to unopposoble thumb
Allows adjacent cells to communicate for electric and metabolic fxns - connexons

48. appreas in 30s to 40s - does not regress
Degenerative injury due to repeated use - tiny tears in the tendons and muscles - may be inflammatory - lateral epicondyle is tennis - medial epicondyle is golf
Cherry hemangioma
Chondrosarcoma
Sites of tibial attachment

49. immune mediated - widespread - non - caseating granulomas - dz - affected population and elevated serum level
Sarcoidosis - black females - ACE
Age - obesity and joint deformity
Femoral - thing flexion and leg extension - anterior thigh and medial leg
Peroneal everts and dorsiflexes - foot dropPED; tibial inverts and plantarflexes - can't stand on Tip toes

50. Decrease marrow space in osteopetrosis leads to what?
Fibroblast growth factor receptor (FGFR3) inhibits chondrocyte proliferation
Impetigo - s aureus - s pyogenes
Anemia - thrombocytopenia - infection - extramedullary hematopoiesis
Chondrosarcoma - pelvis - spine - scapula - humerus - tibia - or femur