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Test your basic knowledge |
Musculoskeletal
Start Test
Study First
Subject
:
health-sciences
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What is the test for drug induced lupus
Anti - histone
Median nerve
Thymoma
Outer arm
2. What are the potential causes of gout
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3. common mole - benign
Glucocorticoids
Nevocellular nevus
Median nerve - same fingers but not on the hand
Men and women > 70 - senile osteporosis
4. What receptor is constitutively activated in achondroplasia and What does it do
Anti ds DNA - poor prognosis
Fibroblast growth factor receptor (FGFR3) inhibits chondrocyte proliferation
Serratus anterior - connects scapular to thoracic cage - abduction above horizontal position - injured in mastectomy - winged scapula and lymphedema
Endochondroma
5. locally invasive but rarely mets skin cancer - rolled edges - with central ulceration - cancer and gross path
Loss of medial lumbrical fxn; 4th and 5th digits are clawed - when try to open hand - pinky and ring finger stay clawed
Basal cell carcinoma - pearly papules - commonly with telangiectasias
Onion skin - 11:22 - diaphysis of long bones - pelvis - scapula - ribs
Median - lateral finger and wrist flexion - dorsal palmar aspects of lateral 3.5 fingers/thenar eminence - ape hand - carpal tunnel syndrome
6. What is the classic presentation of osteoarthritis
Pain in weight bearing joints at the end of the day and improving with rest
Xeropthalmia - xerostomia - arthritis
Small cell cancer of the lung - improve with muscle use - no change with ACHE inhibs
Strawberry hemangioma
7. What does lack of ATP cause
Radial - BEST extensors - posterior arm and dorsal hand/thumb - wrist drop
Verrucae vulgaris
Keloid
Rigor mortis
8. What are the thin lines along the Z line
Actin
Troponin C - conformational change that moves tropomyosin out the myosin binding groove on actin filaments
Chondrosarcoma - pelvis - spine - scapula - humerus - tibia - or femur
Inc CK - inc aldolase - and positive ANA and anti Jo -1 - steroids
9. hypothenar eminence - nerve and muscles
Interossei and adductor policis
Median nerve
Type III - RF
Ulnar - opponens digiti minimi - abductor digiti minimi - flexor digiti mimini
10. Deposition of calcium pyrophosphate cyrstals within the joint space
Pseudogout
Fibrinoid necrosis surrounded by palisading histiocytes
Large goints (knee)
Flex the MCP joints and extend both the DIP and PIP joints
11. pruritic eruption - commonly on skin flexures - of associated with asthma - allergic rhinitis
Verrucae vulgaris
Defective mineralization/calcification of osteoid - osteomalacia in adults and ricketts in kids
Atopic dermatitis - eczema
Carbonic anhydrase II
12. What is CREST syndrome and What antibody is it associated with
Calcinosis - raynauds - esophageal dysmotility - sclerodactyly - telangiectasia - anti centromere antibody
Osteoblastoma
Viral - maybe paramyxovirus
Psoriasis
13. What other lesion can cause the appearnce of the ulnar claw
Down T tubule
Pagets dz - bone infarcts - radiation - familial retinoblastoma - codman's triangle or sunburst pattern from elevation of periosteum - poor prognsosis
Pustule
Making fist with a proximal median nerve lesion
14. hyperplasia of stratum spinosum - associated with hyperinsulinemia (cushings - DM) and visceral malignancy
Deep branch of radial nerve
Asymmetric - swollen - red - painful joint - often MTP (podagra) - tophus formation on external ear - olecranon bursa - achilles tendon
Acanthosis nigcricans
Mesenchymal stem cells in periosteum
15. yellow when parallel and blue when perpendicular
Type 2 - dec mitochondria and myoglobin - inc anaerobic glycolysis
Renal - pulm - CV - GI - 75% female
Gout
Pseudogout
16. Thenar eminence - nerve and muscles
Long thoracic nerve
Median - opponens pollicis - abductors pollicis brevis - flexor pollicis brevis
Dermatitis
Head - trunk - extremities - common benign neoplasm in older persons
17. Where is C8 dermatome
Pustule
Parakeratosis
4th and 5th finger
Median nerve
18. What are the systemic symptoms found in RA
Gout
Fever - fatigue - pleuritis - pericarditis
Onion skin - 11:22 - diaphysis of long bones - pelvis - scapula - ribs
Pemphigus vulgaris
19. malignant cartilaginous tumor in men 30 to 60 - Name and common location
Medial 1.5 fingers - hypothenar eminence
McCune - Albright syndrome
Chondrosarcoma - pelvis - spine - scapula - humerus - tibia - or femur
Anti - histone
20. interlacing trabeculae of woven bone surrounded by osteoblasts
Calcinosis - raynauds - esophageal dysmotility - sclerodactyly - telangiectasia - anti centromere antibody
Osteoid osteoma
Ulnar nerve - intrinsic muscles of hand
Osteoarthritis
21. Where is T2 dermatome
Dry eyes - dry mouth - nasal and vaginal dryness - chronic bronchitis - reflux esophagitis and No arthritis
Endochondroma
Iliac crest
Axilla
22. What autoantibodies are formed in sjogrens syndrome
Seborrheic keratosis
Head - trunk - extremities - common benign neoplasm in older persons
ANA - sensitive but not specific
Ribonucleoprotein antigents - SS- A and SS- B (Ro and La)
23. yellow when perpendicular and blue when parallel
Pseudogout
Increase in both osteoblast and osteoclast activity
Large goints (knee)
Ulnar - opponens digiti minimi - abductor digiti minimi - flexor digiti mimini
24. In which joints does pseudogout typically occur
Large goints (knee)
Boutonniere - swan neck - zthumb
Infraspinatus - laterally rotates arm
EtOH metabolites compete for same excretion site in kidney as uric acid - causing dec uric acid secretion and subsequent buildup
25. dactylitis and pencil in cup deformity on xray - patchy skin rash and joint pain
Psoriatic arthritis - occurs is less than 1/3 of psoriasis pts
Phosphorylated
Pseudogout
NC migration
26. What causes golf or tennis elbow
Median - lateral finger and wrist flexion - dorsal palmar aspects of lateral 3.5 fingers/thenar eminence - ape hand - carpal tunnel syndrome
Degenerative injury due to repeated use - tiny tears in the tendons and muscles - may be inflammatory - lateral epicondyle is tennis - medial epicondyle is golf
Ulnar - opponens digiti minimi - abductor digiti minimi - flexor digiti mimini
Intraepidermal bullae involving the skin and oral mucosa
27. How is chondrosarcoma described
Hyperkeratosis
Serratus anterior - connects scapular to thoracic cage - abduction above horizontal position - injured in mastectomy - winged scapula and lymphedema
Expansile glistening mass within the medullary cavity
Wheal
28. What is the characteristic appearance of bone - the common translocation - area of - and bones affected
Gout
Lesioned by midshaft fracture of humerus
Expansile glistening mass within the medullary cavity
Onion skin - 11:22 - diaphysis of long bones - pelvis - scapula - ribs
29. What are the associations for sjogrens syndrome
B27 - no RF - males
Inc CK - inc aldolase - and positive ANA and anti Jo -1 - steroids
Parotid enlargement - inc risk of B cell lymphoma - dental caries
Anterior interosseous nerve
30. What are common features of lupus
Medially rotates and adducts arm
Outer arm
Supraspinatus - infraspinatus - teres minor - subscapularis - SItS
Wire - loop lesions in kidney with immune complex deposition - death from renal failure and infxns
31. What is the Auspitz sign
Ribonucleoprotein antigents - SS- A and SS- B (Ro and La)
AP depol opens voltage gated Ca channels - inducing NT release
Osteoma (gardners syndrome) - new piece of bone grows on another bone - often skull
In psoriasis - bleeding spots when scales are scraped off
32. What is the Sicca syndrome
Recurrent branch of the medain nerve
Mesenchymal stem cells in periosteum
Hands and face - ulcerative red lesion - locally invasive bur rare metastasis - associated with chronic draining sinuses and keratin pearls
Dry eyes - dry mouth - nasal and vaginal dryness - chronic bronchitis - reflux esophagitis and No arthritis
33. What medication is contraindicated in osteoporosis
Glucocorticoids
Integrin binds laminin in BM
Type III - RF
After a large meal or EtOH conspumption
34. warts on genitals
Condyloma acuminatum - caused by HPV
Palisading
TB from dissemination and lyme dz
Carbonic anhydrase II
35. What lesion causes winged scapula
Long thoracic nerve
Carbonic anhydrase II
Onion skin - 11:22 - diaphysis of long bones - pelvis - scapula - ribs
Hands and face - ulcerative red lesion - locally invasive bur rare metastasis - associated with chronic draining sinuses and keratin pearls
36. What are the lab findings in osteopetrosis
EtOH metabolites compete for same excretion site in kidney as uric acid - causing dec uric acid secretion and subsequent buildup
Nl - thickened dense bones
Anti ds DNA - poor prognosis
3rd finger
37. bone replaced by fibroblasts and irregular bony trabeculae affecting many bones
< 2mc found in proximal tibia and femur - men < 25
Polyostotic fibrous dysplasia
Dec estrogen causes inc bone resorption - postmenopausal
4th and 5th finger
38. What muscle the long thoracic nerve innervate - What does it do - and when can it be injured
Staph scalded skin syndrome
Type 2 - dec mitochondria and myoglobin - inc anaerobic glycolysis
Troponin C - conformational change that moves tropomyosin out the myosin binding groove on actin filaments
Serratus anterior - connects scapular to thoracic cage - abduction above horizontal position - injured in mastectomy - winged scapula and lymphedema
39. What test if specific for lupus but doesn't indicate prognosis
Anti Smith
Torn MCL
Impetigo - s aureus - s pyogenes
Ephelis
40. What does soft bones result from and What is the dz called in adults and children
Inc spinosum - dec granulosum
Voltage sens - dihydropiridine R coupled to ryanodine recpetor - conformational change in the SR - releasing Ca2+
Defective mineralization/calcification of osteoid - osteomalacia in adults and ricketts in kids
Torn MCL
41. What causes a lesion in the axillary nerve
Giant cell tumor (osteoclastoma) - double bubble or soap bubble
Fracture of surgical neck - dislocation of the humerus - intramuscular injections
Precocious puberty
NSAIDs (indomethacin) colchicine
42. IBS - 2 dz's
Crohns and ulcerative colitis
Recurrent branch of the median nerve
Median nerve
Actinic keratosis
43. What are the layers of of the epidermis from surface to base
Corneum - lucidum - granulosum - spinosum - basalis
Phosphate is liberated from the myosin head
Polymyositis - shoulders - perifasicular inflammation
Elevated ESR and nl CK - prednisone
44. What does abnl passive abduction of the knee indicate
Torn MCL
Upper trunk compression - biceps - brachialis - corachobrachialis - flexion of arm at elbow - sensory = lateraly forearm
Ulnar deviation - subluxation - bakers cysts (behind knee)
Ulnar nerve
45. Trauma to lateral aspect of leg or fibula neck fracture - nerve - motor and sens def
Obturator - thigh adduction - medial thigh
Musculocutaneous
Common peroneal - foot eversion and dorsiflexion - toe extention - foot drop - foot slap - stepped gaint - anterolateral leg and dorsal aspect of foot for sensory
Lower trunk of brachial plexus
46. potentially fatal autoimmune disorder with IgG antibody against desmosomes
Pemphigus vulgaris
Pityriasis rosea
Ulnar deviation - subluxation - bakers cysts (behind knee)
Scleroderma
47. What organisms can cause chronic infectious arthritis
Dec Ca - dec phos - nl alk phos - inc PTH - soft bones
Pemphigus vulgaris
Mesenchymal stem cells in periosteum
TB from dissemination and lyme dz
48. What kind of endocrine abnl are associated with McCune Albright
Psoriatic arthritis - occurs is less than 1/3 of psoriasis pts
Myasthenia gravis - autoAb against ACH receptors causing ptosis - diplopia - general weakness -
Precocious puberty
EtOH metabolites compete for same excretion site in kidney as uric acid - causing dec uric acid secretion and subsequent buildup
49. excessive fibrosis and collagen deposition throughout the body - common in skin manifesting as puffy taut skin with absence of wrinkles
Scleroderma
Ulnar nerve
Pemphigus vulgaris
Ewings sarcoma - aggressive with early mets - but responsive to chemo
50. What is a precursor to squamous cell carcinoma
Men and women > 70 - senile osteporosis
Muslce use - nerve stim/compound muscle test
Biceps
Actinic keratosis