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Reproductive

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. < 21 day cycle
S aureus
Polymenorrhea
Just prior to ovulation
Malignant in males not in females

2. What is the flaggelum derived from
Squamo - columnar jxn
One of the centrioles
Polyhydramnios
6

3. histologic type of fibrocystic with fluid filled - blue dome and ductal dilation
Visceral - somatic nerves in pudendal
Broad ligament
Oligohydramnios
Cystic

4. Which gynecologic tumors have the worst prognosis?
Cirrhosis - testicular tumor - puberty - old age - klinefelter's syndrome - drugs
Ovarian > cervical > endometrial
Mature teratoma
Spermatocele

5. defect in androgen receptor resulting in normal appearing female - rudimentry vagina - no uterus or uterine tubes
5 alpha reductase - inhibited by finesteride
Androgen insensitivity syndrome - 46 XY
Production of a thick cervical mucus
Granulosa cell - aromatase - androstenedione - estrogen

6. What does progesterone do to body temp
Increase
Blacks
Hemolysis - elevated liver enzymes - low platelets
Immature

7. What is DHT responsible for in late development
Spermatocele
Partial
Prostate growth - balding - and sebaceous gland activity
Prematurity

8. Overexpression of which receptors is common iwht malignant breast tumors
Estrogen/progesterone receptors - erb - B2 - HER2 an EGF receptrs
Endocervix
Suckling - inc oxytocin - prolactin
Meigs syndrome

9. What does progesterone do to estrogen receptors
Seminiferous tubules - epididymis - vas deferens - ejaculatory ducts - nothing - urethra - penis
Ectocervix
Down regulation
Endometrial carcinoma

10. histo: simple columnar epithelium - pseudostratified tubular glands
Cystic
Hemorrhage
Feedback inhibition
Uterus

11. What pathologic states cause increases in hCG
Right gonadal vein - IVC
Hydatidiform moles - choriocarcinoma - gestational trophoblastic tumors
Fibroadenoma
Bowen's dz - carcinoma in situ of the penis

12. Which system and nerve allow for erection in the male?
Placental insufficiency - bilateral renal agenesis - posterior urethral valves - potter's syndrome
E coli
PANS - pelvic nerve
Yolk sac - endodermal sinus - tumor

13. Uterin fundus to labia majora
Decreasing progesterone
Mucinous cystadenocarcinoma
Cervix
Round ligament of uterus

14. testes present with non male external genitals
Male pseudoHerm
Phyllodes tumor
Unopposed estrogen - obesity - diabetes - HTN - nulliparity - late menopause
Decreasing progesterone

15. Where is testosterone secreted into?
Prementsrual breast pain and multiple lesions
The semiT and the blood vessels
2 months
Post menopausal bleeding

16. heavy - irregular menstruation at irregular intervals
GnRH from hypoTh - LH and FSH from ant pituitary
Menometrorrhagia
Ovary
Adolescents

17. leiomyoma and leiosarcoma have an increased incidence in which ethnic group
Blacks
Round ligament of the uterus
Fertilization 'an egg met a sperm'
Prematurity

18. Wher does dysplasia and carcinoma in situ of the cervix usually begin
Hyperthyroidism - contains functional thyroid tissue
Smooth muscle
Squamo - columnar jxn
Prematurity

19. When does endometiral carcinoma usually occur
55-65
Cirrhosis - testicular tumor - puberty - old age - klinefelter's syndrome - drugs
Invasive ductal
Unopposed estrogen - obesity - diabetes - HTN - nulliparity - late menopause

20. cystic swelling of chorionic villi and proliferation of chorionic epithelium that presents with abnormal vaginal bleeding
Epithelial hyperplasia
Hydatidiform mole
Uterus
Pseudohermaphroditism

21. How is dyslpasi and carcinoma in situ of the cervix classified
CIN 1 - 2 - 3
Suspensory ligament of ovaries
Low progesterone
One of the centrioles

22. What is the lymphatic drainage of the distal 1/3 of the vagina/scrotum/vulva
Low back pain with increased serum alk phos
Fibromas
Superficial inguinal lymph nodes
Choriocarcinoma

23. what metabolic disorder is assocaited with PCOS
Prophase
Insulin resistance
Milk letdown - uterine contractions?
51 yo

24. when do primary oocytes begin meiosis I
Ovary
During fetal life
Fertilization 'an egg met a sperm'
Suspensory ligament of ovaries

25. What is the single most important prognostic factor for malignant breast tumors
Testosterone
Feedback inhibition
Prementsrual breast pain and multiple lesions
Axillary node involvement

26. ecsematous patches on nipple and/or vulva - suggests underlying carcinoma

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27. What does hCG do in the first trimester to maintain the corpus luteum
Distention and hypertrophy of bladder - hydronephrosis - UTIs - not premalignant
Mimics LH
Inc Ca in - smooth muscle contraction - vasocxn - antierectile
Left

28. How is beta hCG detectable in blood or urine for a home pregnancy test
1 week - 2 weeks
DHT - testosterone - androstenedione
Fructose
Left

29. Which phase varies and in length and Which is usually 14 days (menstrual cycle)
Complete
Follicular phase varies - luteal phase is 14
4
Endometriosis

30. Which cells secrete beta hCG
IV mag sulfate - diazepam
Granulosa cell - aromatase - androstenedione - estrogen
Trophoblasts
Erythroplasia of Queyrat - carcinoma in situ of penis

31. decreased synthesis of gonadotropin in the ant pit - anosmia - lack of secondary sex characteristics
Testosterone secreting tumor - exogenous steroids
Kallman
Aortic bicuspid valve
Dysgerminoma

32. Where is androstenedione made?
Hydrocele
Paget cell
Delivery of fetus
Adrenal gland

33. disagreement between the phenotypic and gonadal sex
DES in utero (DES is a sythetic estrogen)
Prostatic acid phosphatase and PSA
Mitochondria
Pseudohermaphroditism

34. Does a leiomyoma progress to leiosarcoma
Squamo - columnar jxn
Phyllodes tumor
Tight junctions between sertoli cells
No

35. large cells in epidermis with clear halo
Paget cell
GnRH from hypoTh - LH and FSH from ant pituitary
Call exner bodies
Just prior to ovulation

36. Where is SCC of the penis more common and What is it associated with
Blacks
Asia - Africa - S. America - HPV - lack of circumcision
Fructose
The ampulla - occurs within 1 day of ovulation

37. In what group are malignant breast tumors most commonly seen
Upregulation - LH surge - ovulation
Post menopausal
Placental ischemia due to impaired vasodltn of spiral arteries resulting in increased vasc tone
Placenta previa

38. What is the karyotype of a partial mole
69 xxy
Distention and hypertrophy of bladder - hydronephrosis - UTIs - not premalignant
50 times
Prementsrual breast pain and multiple lesions

39. Where does FSH work - what enzyme works there - what substrate comes in and what leaves
Fibrosis
Granulosa cell - aromatase - androstenedione - estrogen
Uterus
Right gonadal vein - IVC

40. What does increasing estrogen do to GnRH receptors on ant pit - and What does this lead to...
Upregulation - LH surge - ovulation
Inc cGMP - smooth muscle relax - vasodltn - proerectile
The semiT and the blood vessels
Low back pain with increased serum alk phos

41. breast path - diseases of the major duct
Comedocarcinoma
Estrogen/progesterone receptors - erb - B2 - HER2 an EGF receptrs
Fibrcystic change - ductal cancer
Estrogen overstimulation

42. predisposing factor to clear cell adenocarcinoma of the vagina
Low progesterone
Testosterone
DES in utero (DES is a sythetic estrogen)
Fibroadenoma

43. What complications are associated with polyhydramnios

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44. multilocular cyst lined by mucus secreting epi - benign - intestine like
Spermatogonia (germ cells)
Tunica vaginalis lesions
Mucinous cystadenoma
Develop both male and female internal genitalia and male external genitalia

45. histo: stratified squamous epithelium - nonkeratinized
Andogren binding protein - anti mullerian hormone
DIC
Serous cystadenoma
Vagina

46. How many functional sperm does 1 germ cell creat?
4
Enlarged bilateral cystic ovaries - amenorrhea - infertility - obesity - and hirsutism
Decrease
Endocervix

47. What is the genetic material in the primary oocyte?
Diploid - 4N - 46 sister chromatids
Comedocarcinoma
Intraductal papilloma - breast abscess - mastitis
Estradiol

48. increases in which hormone are associated with BPH
Estradiol and possible growth promoting effects of DHT
Preeclampsia
Medullary
Just prior to ovulation

49. Some drugs cause awesome knockers
Squamous cell carcinoma
Oligomenorrhea
Sprinolactone - digitalis - cimetidine - alchohol - ketoconazole
Prostate growth - balding - and sebaceous gland activity

50. What is the main source of energy for spermatozoa
Premature ovarian failure (Pof)
Fibrosis
PANS - pelvic nerve
Fructose