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Reproductive

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. List the estrogens in order of decreasing potency
Distention and hypertrophy of bladder - hydronephrosis - UTIs - not premalignant
Severe bleeding iron def anemia - miscarriage
Estradiol > estrone > estriol
Prostatic acid phosphatase and PSA

2. small breast tumor that grows in lactiferous ducts - typically beneath the areola with serous or bloody nipple discharge
Testosterone secreting tumor - exogenous steroids
Para - aortic lymph nodes
Intraductal papilloma
Estrogen overstimulation

3. ovaries plus virilized external genitalia due to excessive and inappropriate exposure to androgenic steroids during early gestation
Down regulation
Mucinous cystadenoma
Testosterone secreting tumor - exogenous steroids
Female pseudoHerm

4. What is the lymphatic drainage of the proximal 2/3 of the vagina/uterus
Obdurator - exterinal iliac - hypogastic nodes
Final stage of spermatogenesis - spermiogenesis - spermatid to spermatozoa
Down regulation
DCIS

5. What does estrogen do to estrogen - LH and progesterone recepotrs
Upregulation
Inhibition of HCG access
Call exner bodies
Final stage of spermatogenesis - spermiogenesis - spermatid to spermatozoa

6. ecsematous patches on nipple and/or vulva - suggests underlying carcinoma

7. common cause of recurrent miscarriage in the 1st week
Low progesterone
Haploid - 2N - 23 sister chromatids
Andogren binding protein - anti mullerian hormone
Placental insufficiency - bilateral renal agenesis - posterior urethral valves - potter's syndrome

8. What are causes of female pseudoHerm
Hyperthyroidism - contains functional thyroid tissue
Congenital adrenal hyperplasia - exogenous administration of steroids
Inhibition LH and FSH
17beta estradiol

9. reinke crystals - androgen producing - gynecomastia in men - precocious puberty in boys - golden brown color
Krukenburg tumor
Testosterone
Peyronie's dz
Leydig cell tumor

10. What does FSH do
Stimulates sertoli cells to produce ABP and inhibin
Endometrial carcinoma
Placenta previa
PCOS - obesity - Asherman's - HPO axis defect - Pof - hyperprolactinemia - thryoid - eating disorders - cushging's - adrenal insuff

11. What substances other than inhibin do sertoli cells produce?
Stimulate glandular secretions - and spiral artery development
Andogren binding protein - anti mullerian hormone
Stimulates sertoli cells to produce ABP and inhibin
Preeclampsia

12. What does hCG do in the first trimester to maintain the corpus luteum
Placental ischemia due to impaired vasodltn of spiral arteries resulting in increased vasc tone
Alpha1 antagonists - terazosin - tamsulosin - finasteride
Partial
Mimics LH

13. What is the most common pathogen in acute mastitis
Retrograde mentrual flow or ascending infection
Decreasing progesterone
S aureus
Aortic bicuspid valve

14. What is a concern of early menopause
Premature ovarian failure (Pof)
Complete
Adolescents
Placenta acreta

15. When are phyllodes tumors most common
Teratoma
Chromosomal abnormalities
5 alpha reductase - inhibited by finesteride
In the 6th decade of life

16. What is the genetic material in the primary oocyte?
Esophogeal/duodenal atresia - can't swallow - anencephaly
Defective androgen receptor
Fibrcystic change - ductal cancer
Diploid - 4N - 46 sister chromatids

17. Why does the skin resemble an orange peel in inflammatory type of maligantn breast tumor
50 times
Menopause
Menometrorrhagia
Neoplastic cells block lymphatic drainage

18. defective decidual later allows placenta to attach to myometrium - massive bleeding after delivery
Placenta acreta
Yolk sac - endodermal sinus - tumor
Hyperestrogenism
Male pseudoHerm

19. What is the clinical manifestation of PCOS
Dysuria - frequency - urgency - low back pain
Granulosa cell tumor
Endometrial carcinoma
Enlarged bilateral cystic ovaries - amenorrhea - infertility - obesity - and hirsutism

20. HTN - proteinuria and edema
Preeclampsia
Syncytiotrophoblasts of placenta
Dilation and curettage and methotrexate
HPV 16 - 18

21. Where is SCC of the penis more common and What is it associated with
Cystic
Asia - Africa - S. America - HPV - lack of circumcision
Inc risk for carcinoma
Cardinal ligament

22. What is the order of events in the menstrual cycle
Comedocarcinoma
Fructose
Estrogen - LH surge - ovulation - progesterone from CL - menstruation
Fat necrosis

23. What is hydatidiform mole and precurosor of...
Smoking - HTN - cocaine
Development of genitalia and breast - growth of follicle - hormonal interactions with HPG accesss - and inc transport proteins like SHBG inc HDL and dec LDL
Tubular carcinoma
Choriocarcinoma

24. What stimulation after labor induces lactation
Decreasing progesterone
Fat necrosis
Weight loss - OCP - gonadotropin analogs - clomiphene - sprinolactone - surgery
Brenner tumor

25. In What age group are ovarian germ cell tumors most common
Intraductal papilloma
Adolescents
Complete
Prematurity

26. What estrogen does the placenta secrete
Fertilization 'an egg met a sperm'
Necrosis - hemorrhage - can protrude from the cervix and bleed - tendency to recur
Estradiol > estrone > estriol
Estradiol

27. premature detachment of placenta from implantation site leading to fetal death
Peyronie's dz
Yolk sac - endodermal sinus - tumor
Abruptio placentae
Increased FSH

28. Breast path - disease that occurs at the nipple

29. What is the main source of energy for spermatozoa
Fructose
Epithelial hyperplasia
Low back pain with increased serum alk phos
Menopause

30. What does SEVEN Up stand for in regards to the pathway of sperm
Tubular carcinoma
Hyperestrogenism
Varicocele
Seminiferous tubules - epididymis - vas deferens - ejaculatory ducts - nothing - urethra - penis

31. What does estrogen do to FSH and LH
Left gonadal vein - left renal vein - IVC
Feedback inhibition
Intraductal papilloma
Partial

32. testes present with non male external genitals
Milk letdown - uterine contractions?
The semiT and the blood vessels
S aureus
Male pseudoHerm

33. What is the source of estrogen after menopause
No
Peripheral conversion of androgens
Sarcoma botryoides - a rhabdomyosarcoma variant
Ectopic preg

34. breast path - diseeases of the lobules
Cirrhosis - testicular tumor - puberty - old age - klinefelter's syndrome - drugs
Defective androgen receptor
Lobular carcinoma - sclerosing adenosis
DCIS

35. Where does LH work - what enzyme works there and what product is secreted
Theca cell - desmolase - androstenedione
Paget cell
Proliferation
Hydatidiform mole

36. What increases risk for endometrial carcinoma
Tunica vaginalis lesions
Relaxation
Prementsrual breast pain and multiple lesions
Unopposed estrogen - obesity - diabetes - HTN - nulliparity - late menopause

37. Which system and nerve are responsible for emission
Blacks
Leydig cell tumor
SANS - hypogastric nerve
Mitochondria

38. > 35 day cycle
Testosterone
CIN 1 - 2 - 3
Oligomenorrhea
Fibromas

39. Large bulky breast mass of connective tissue and cysts with leaf like projections
Call exner bodies
Phyllodes tumor
History of infertility - salpingitis - ruptured appendix - prior tubal surgery
Vagina

40. Risk factors for ectopic pregs
History of infertility - salpingitis - ruptured appendix - prior tubal surgery
Dilation and curettage and methotrexate
Prostate growth - balding - and sebaceous gland activity
1000 times

41. decreased synthesis of gonadotropin in the ant pit - anosmia - lack of secondary sex characteristics
Kallman
Follicular cyst
Paget cell
Syncytiotrophoblasts of placenta

42. pain with or without bleeding - inc in hCG - sudden lower abdominal pain - mistaken for appendicitis
Ectopic preg
Inc AFP and hCG
Prophase
Androgen insensitivity syndrome - 46 XY

43. Connects uterus - fallopian tubes and ovaries to pelvic side wall - contains ovaries - fallapian tubes - and round ligaments of uterus
Yolk sace - endodermal sinus - tumor
Prior c section - inflammation - placenta previa
Inhibition LH and FSH
Broad ligament

44. How does exogenous testosterone create azoospermia
Inhibition of HCG access
Syncytiotrophoblasts of placenta
Necrosis - hemorrhage - can protrude from the cervix and bleed - tendency to recur
Corpus luteum cyst

45. What does inhibin do?
Inc risk for carcinoma
Inhibit FSH
Posterior lobe peripheral zone
The anterior pituitary and hypothalamus

46. What does progesterone do to body temp
Increase
Squamo - columnar jxn
Decreasing progesterone
Stimulates testosterone release from leydig cells

47. headache - blurred vision - abdominal pain - edema of face and extremeties - altered mentation - hyperreflexia in pregnancy
Axillary node involvement
Preeclampsia clinical
Estradiol > estrone > estriol
Obdurator - exterinal iliac - hypogastic nodes

48. >1.5 -2 L of amniotic fluid
Polyhydramnios
Ectocervix
Erythroplasia of Queyrat - carcinoma in situ of penis
Follicular phase varies - luteal phase is 14

49. Which phase varies and in length and Which is usually 14 days (menstrual cycle)
History of infertility - salpingitis - ruptured appendix - prior tubal surgery
Serous cystadenoma
Hydatidiform moles - choriocarcinoma - gestational trophoblastic tumors
Follicular phase varies - luteal phase is 14

50. What are the useful tumor parkers in prostatic adenocarcinoma
Estrogen/progesterone receptors - erb - B2 - HER2 an EGF receptrs
Inc AFP and hCG
Prostatic acid phosphatase and PSA
One of the centrioles