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Reproductive

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. What is the clinical manifestation of PCOS
Smooth muscle
Left gonadal vein - left renal vein - IVC
Enlarged bilateral cystic ovaries - amenorrhea - infertility - obesity - and hirsutism
Metrorrhagia

2. What complications are associated with oligohydramnios

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3. What is the source of estrogen after menopause
Neoplastic cells block lymphatic drainage
Adrenal gland
20 to 40
Peripheral conversion of androgens

4. histo: simple columnar epithelium - ciliated
Varicocele
Immature
Low back pain with increased serum alk phos
Fallopian tube

5. Which teratoma - mature or immature - is aggresively malignant
Prophase
Cystic
5 alpha reductase - inhibited by finesteride
Immature

6. What are the treatments for PCOS
Weight loss - OCP - gonadotropin analogs - clomiphene - sprinolactone - surgery
Pseudohermaphroditism
Tubular carcinoma
Erythroplasia of Queyrat - carcinoma in situ of penis

7. predisposing factor to clear cell adenocarcinoma of the vagina
DES in utero (DES is a sythetic estrogen)
Osteoblastic in bone
Unopposed estrogen - obesity - diabetes - HTN - nulliparity - late menopause
Sertoli cell tumor

8. What is the single most important prognostic factor for malignant breast tumors
Inc risk for carcinoma
Broad ligament
Axillary node involvement
Prostate growth - balding - and sebaceous gland activity

9. What are risk factors for abruptio placentae?
Smoking - HTN - cocaine
Final stage of spermatogenesis - spermiogenesis - spermatid to spermatozoa
Calcifications
Cystic

10. What does estrogen do to FSH and LH
Testosterone
Fibromas
Call exner bodies
Feedback inhibition

11. disagreement between the phenotypic and gonadal sex
Pseudohermaphroditism
Granulosa cell tumor
Congenital adrenal hyperplasia - exogenous administration of steroids
Complete

12. What is the presentation of fibrocystic dz
Prementsrual breast pain and multiple lesions
Peyronie's dz
Testosterone
Stimulates sertoli cells to produce ABP and inhibin

13. tumor is fleshy - cellular - with a lymphocytic infiltrate - good prognosis
Broad ligament
Medullary
Pseudohermaphroditism
Peripheral adipose tissue

14. histo: stratified squamous epithelium - nonkeratinized
Lateral invasion can block ureters causing renal failure
Vagina
Krukenburg tumor
1000 times

15. What becomes the main source of hCG
Neoplastic cells block lymphatic drainage
Syncytiotrophoblasts of placenta
Suckling - inc oxytocin - prolactin
Obdurator - exterinal iliac - hypogastic nodes

16. attachment of palceta to lower uterine segment that may occlude internal os - painless bleeding in any trimester
Delivery of fetus
Placenta previa
Aortic bicuspid valve
Metaphase

17. List the estrogens in order of decreasing potency
Estradiol > estrone > estriol
Stimulates sertoli cells to produce ABP and inhibin
Upregulation
Hemolysis - elevated liver enzymes - low platelets

18. What is DHT responsible for in late development
Slight increase - 1.5 to 2
Prostate growth - balding - and sebaceous gland activity
Round ligament of uterus
Stimulates testosterone release from leydig cells

19. multilocular cyst lined by mucus secreting epi - benign - intestine like
Complete
Milk letdown - uterine contractions?
Increase in size in pregs - decrease in size meno - estrogen sens
Mucinous cystadenoma

20. breast path - diseeases of the lobules
Paget cell
Stimulate glandular secretions - and spiral artery development
Prementsrual breast pain and multiple lesions
Lobular carcinoma - sclerosing adenosis

21. hyperandrogenism due to deranged steroid synthesis by theca cells - inc LH leading to anovulation
Anovulatory cycles - hormone replacement therapy - PCOS - granulosa cell tumor
Congenital adrenal hyperplasia - exogenous administration of steroids
DCIS
PCOS

22. >1.5 -2 L of amniotic fluid
Preeclampsia + siezures
Polyhydramnios
Yolk sac - endodermal sinus - tumor
Teratoma

23. benign painless lump - forms as a result of injury to breast tissue - possible history of trauma
55-65
Superficial inguinal lymph nodes
Fat necrosis
Production of a thick cervical mucus

24. What is the most common cause of breast lumps from age 25 to menopause
Fibrocystic disease
Brenner tumor
Serous cystadenocarcinoma
Testosterone

25. Where does LH work - what enzyme works there and what product is secreted
Theca cell - desmolase - androstenedione
Squamo - columnar jxn
Milk letdown - uterine contractions?
50 times

26. What is the prognosis for seminoma
Sertoli cells - and adipose tissue via aromatase
Good - late metastasis
Fertilization 'an egg met a sperm'
Preeclampsia + siezures

27. How many days after fertilization does implantation occur?
Prior c section - multiparity
Menopause
Golgi
6

28. What stimulation after labor induces lactation
Decreasing progesterone
Stimulates testosterone release from leydig cells
Final stage of spermatogenesis - spermiogenesis - spermatid to spermatozoa
Placental ischemia due to impaired vasodltn of spiral arteries resulting in increased vasc tone

29. histo: stratified sqamous epithelium
Whorled pattern of smooth muscle bundles
Ectocervix
Oligohydramnios
Increase (and LH)

30. is fibroadenoma a precursor to breast cancer
No
Obdurator - exterinal iliac - hypogastic nodes
Good - late metastasis
46 xx

31. androblastoma from sex cord stroma
Testis determining factor
Comedocarcinoma
Sertoli cell tumor
Hemolysis - elevated liver enzymes - low platelets

32. Risk factors for ectopic pregs
Both ovary and testicular tissue present - ambiguous genitals - rare 46 XX - 47XXY
Develop both male and female internal genitalia and male external genitalia
History of infertility - salpingitis - ruptured appendix - prior tubal surgery
Peyronie's dz

33. Short stature - ovarian dysgenesis - shield chest - no barr body - webbing of the neck

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34. What substances other than inhibin do sertoli cells produce?
Follicular cyst
Andogren binding protein - anti mullerian hormone
Sertoli cells - and adipose tissue via aromatase
Primary hypogonadism

35. in chronic prostatitis is bacterial or abacterial more common
Maintenance
Abacterial
DIC
No

36. What is a complication of invasive carcinoma
Lateral invasion can block ureters causing renal failure
Increased FSH
Inc estrogen - inc total nunmber of cycles - older age at 1st live birth - obesity
Puberty

37. Where is androstenedione made?
Adrenal gland
Prior c section - multiparity
Embryonal carcinoma
Inhibition of HCG access

38. What is the right venous drainage of the ovary/testis
Intraductal papilloma - breast abscess - mastitis
Estradiol
Intraductal papilloma
Right gonadal vein - IVC

39. What hematologic condition is associated with abruptio placentae
Chocolate cyst
Fibrocystic disease
DIC
Corpus luteum cyst

40. inc fluid secondary to incomplete fustion with processus vaginalis
Increase (and LH)
Hydrocele
Fibroadenoma
Maintenance

41. tumor is ductal with caseous necrosis
Comedocarcinoma
Inc Ca in - smooth muscle contraction - vasocxn - antierectile
Testosterone
5 alpha reductase def

42. what bacteria is commone in acute prostatitis
Obdurator - exterinal iliac - hypogastic nodes
Inhibition of HCG access
Increase (and LH)
E coli

43. What is the number 1 risk factor for cervical dysplasia or carcinoma in situ
Left
Multiple sexual partners - also HIV and early sexual intercourse
Female pseudoHerm
Unopposed estrogen - obesity - diabetes - HTN - nulliparity - late menopause

44. Which gynecologic tumors have the worst prognosis?
Feedback inhibition
No
Ovarian > cervical > endometrial
Lobular carcinoma - sclerosing adenosis

45. What is the most common pathogen in acute mastitis
Pseudohermaphroditism
95%
Cystic
S aureus

46. What does FSH do
Prementsrual breast pain and multiple lesions
In the 6th decade of life
Stimulates sertoli cells to produce ABP and inhibin
Estradiol and possible growth promoting effects of DHT

47. What effect does NE have on smoothe muscle in the erectile tissues
Acute mastitis
Leydig cell tumor
Inc Ca in - smooth muscle contraction - vasocxn - antierectile
Complete

48. Where does fertilization most commonly occur?
Inc estrogen - inc total nunmber of cycles - older age at 1st live birth - obesity
Superficial inguinal lymph nodes
S aureus
The ampulla - occurs within 1 day of ovulation

49. What are the functions of oxytocin - maybe
Defective androgen receptor
Milk letdown - uterine contractions?
Sertoli cell tumor
Endometrial carcinoma

50. What are common causes of hyperestrogenism

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