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Reproductive

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Where does fertilization most commonly occur?
CIN 1 - 2 - 3
Inc size and tenderness with inc estrogen
The ampulla - occurs within 1 day of ovulation
Feedback inhibition

2. What do sildenafil and vardenafil do?
Choriocarcinoma
Broad ligament
Inhibit cGMP breakdown
Yolk sace - endodermal sinus - tumor

3. most common testicular cancer in older men
Testicular lymphoma
Teratoma
PANS - pelvic nerve
Feedback inhibition

4. What is DHT responsible for in early development?
Estradiol > estrone > estriol
Squamous cell carcinoma
Peripheral adipose tissue
Differentiation of penis - scrotum and prostate

5. breast path - diseases of the lactiferous sinus
Epithelial hyperplasia
Malignant in males not in females
Intraductal papilloma - breast abscess - mastitis
Mimics LH

6. What estrogen does the placenta secrete
Inc in total - and dec in free fraction
Androgen insensitivity syndrome
Estradiol
Choriocarcinoma

7. What hormones regulate sperm creation?
GnRH from hypoTh - LH and FSH from ant pituitary
Inc Ca in - smooth muscle contraction - vasocxn - antierectile
Cyclic bleeding - chocolate cysts - severe menstrual related pain - infertility
Testosterone - DHT - androstenedione

8. Some drugs cause awesome knockers
Prior c section - inflammation - placenta previa
Para - aortic lymph nodes
Sprinolactone - digitalis - cimetidine - alchohol - ketoconazole
Acute mastitis

9. which cysts results from gonadotropin stimulation and is associated with choriocarcinoma and moles
Hydatidiform moles - choriocarcinoma - gestational trophoblastic tumors
Hirsutism - hot flashes - atrophy of the vagina - osteoporosis - coronary artery disease
Just prior to ovulation
Theca - leutin cysts

10. decreased estrogen - inc FSH - LH - signs of menopause after puberty but before 40
SANS - hypogastric nerve
Premature ovarian failure (Pof)
Phyllodes tumor
Tight junctions between sertoli cells

11. What is the right venous drainage of the ovary/testis
Menometrorrhagia
Right gonadal vein - IVC
Sprinolactone - digitalis - cimetidine - alchohol - ketoconazole
Haploid - 2N - 23 sister chromatids

12. What can happen with no sertoli cell or lack of anti mullerian hormone
Develop both male and female internal genitalia and male external genitalia
Preeclampsia + siezures
Metaphase
Inhibit cGMP breakdown

13. In what phase is meiosis I arrested
Andogren binding protein - anti mullerian hormone
Increase
Prophase
PANS - pelvic nerve

14. What is hydatidiform mole and precurosor of...
Spermatocele
Pseudohermaphroditism
Necrosis - hemorrhage - can protrude from the cervix and bleed - tendency to recur
Choriocarcinoma

15. What cellular structure is the acrosome derived from?
Golgi
No
Hydatidiform moles - choriocarcinoma - gestational trophoblastic tumors
Myometrial tumors

16. What does gynecomastia result from?
Placenta acreta
Sprinolactone - digitalis - cimetidine - alchohol - ketoconazole
Primary hypogonadism
Hyperestrogenism

17. What is a complication of cryptorchidism and why does it occur
Lack of spermatogenesis due to inc temp of testis inside body and associated risk of germ cell tumors
In the 6th decade of life
Fallopian tube
Severe bleeding iron def anemia - miscarriage

18. is fibroadenoma a precursor to breast cancer
No
Distention and hypertrophy of bladder - hydronephrosis - UTIs - not premalignant
Myometrial tumors
Testis determining factor

19. multilocular cyst lined by mucus secreting epi - benign - intestine like
Primary hypogonadism
Fibrosis
Mucinous cystadenoma
Polyhydramnios

20. heavy - irregular menstruation at irregular intervals
Endometriosis
Defective androgen receptor
Menometrorrhagia
Fibrosis

21. What is the treatment for preeclampsia
Brenner tumor
Delivery of fetus
Peripheral conversion of androgens
Spermatogonia (germ cells)

22. Vaginal sqamous cell carcinoma is most often seconday From which site?
Fibroadenoma - phyllodes tumor
Retrograde mentrual flow or ascending infection
Uterus
Cervix

23. breast path - diseeases of the lobules
Invasive ductal
Lobular carcinoma - sclerosing adenosis
Fibroadenoma - phyllodes tumor
No

24. What becomes the main source of hCG
Syncytiotrophoblasts of placenta
Tight junctions between sertoli cells
Meigs syndrome
Klinefelter's - XXY

25. Red velvety plaques - usually involving the glans - similar to Bowen's
Turner's XO
Erythroplasia of Queyrat - carcinoma in situ of penis
20 to 40
Inhibition LH and FSH

26. headache - blurred vision - abdominal pain - edema of face and extremeties - altered mentation - hyperreflexia in pregnancy
Testosterone - DHT - androstenedione
Granulosa cell - aromatase - androstenedione - estrogen
In the 6th decade of life
Preeclampsia clinical

27. Which gynecologic tumors have the worst prognosis?
Hydatidiform moles - choriocarcinoma - gestational trophoblastic tumors
E coli
Ovarian > cervical > endometrial
Multiple sexual partners - also HIV and early sexual intercourse

28. What are the pathologic features of leiosarcoma
Vagina
Necrosis - hemorrhage - can protrude from the cervix and bleed - tendency to recur
Fibrocystic disease
Fructose

29. What are the most common tumors in all females?
Proliferation
Hyperestrogenism
1 week - 2 weeks
Myometrial tumors

30. What sequelae are associated with leiomyoma
Severe bleeding iron def anemia - miscarriage
Anovulatory cycles - hormone replacement therapy - PCOS - granulosa cell tumor
Final stage of spermatogenesis - spermiogenesis - spermatid to spermatozoa
Fibrcystic change - ductal cancer

31. what metabolic disorder is assocaited with PCOS
Female pseudoHerm
Hirsutism - hot flashes - atrophy of the vagina - osteoporosis - coronary artery disease
Insulin resistance
Placental insufficiency - bilateral renal agenesis - posterior urethral valves - potter's syndrome

32. Which system and nerve are responsible for emission
Suckling - inc oxytocin - prolactin
Leydig cell tumor
Inc in total - and dec in free fraction
SANS - hypogastric nerve

33. ecsematous patches on nipple and/or vulva - suggests underlying carcinoma

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34. What does SEVEN Up stand for in regards to the pathway of sperm
Seminiferous tubules - epididymis - vas deferens - ejaculatory ducts - nothing - urethra - penis
Tight junctions between sertoli cells
Inhibit FSH
Cervix

35. How is dyslpasi and carcinoma in situ of the cervix classified
Suspensory ligament of ovaries
DCIS
CIN 1 - 2 - 3
Comedocarcinoma

36. what bacteria is commone in acute prostatitis
Myometrial tumors
E coli
Post menopausal
Varicocele

37. What converts testosterone to DHT
Inhibition LH and FSH
Inc freq of urination - nocturia - difficulty starting/stopping urination - dysuria
5 alpha reductase - inhibited by finesteride
Congenital adrenal hyperplasia - exogenous administration of steroids

38. Prevention of seizures and in preeclampsia
Complete
Develop both male and female internal genitalia and male external genitalia
IV mag sulfate - diazepam
Low progesterone

39. Which cells secrete beta hCG
No
Trophoblasts
Production of a thick cervical mucus
Abacterial

40. Large bulky breast mass of connective tissue and cysts with leaf like projections
Follicular phase varies - luteal phase is 14
Phyllodes tumor
Sprinolactone - digitalis - cimetidine - alchohol - ketoconazole
Lack of spermatogenesis due to inc temp of testis inside body and associated risk of germ cell tumors

41. What does estrogen stimulate in the endometrium
Proliferation
Adenomyosis
Medullary
Upregulation - LH surge - ovulation

42. when do primary oocytes begin meiosis I
Myometrial tumors
Estrogen/progesterone receptors - erb - B2 - HER2 an EGF receptrs
Round ligament of uterus
During fetal life

43. What is the flaggelum derived from
Myometrial invasion
5 alpha reductase def
Final stage of spermatogenesis - spermiogenesis - spermatid to spermatozoa
One of the centrioles

44. What are the functions of oxytocin - maybe
Cyclic bleeding - chocolate cysts - severe menstrual related pain - infertility
Oligomenorrhea
Teratoma
Milk letdown - uterine contractions?

45. What is the common presentation of metastasis in prostate cancer
Hemolysis - elevated liver enzymes - low platelets
Low back pain with increased serum alk phos
Inhibit cGMP breakdown
Fibroadenoma - phyllodes tumor

46. benign painless lump - forms as a result of injury to breast tissue - possible history of trauma
Testosterone
Posterior lobe peripheral zone
Fat necrosis
S aureus

47. breast path - diseases of the terminal duct
Differentiation of penis - scrotum and prostate
Preductal coarctication
Fibroadenoma - phyllodes tumor
Tubular carcinoma

48. When is follicular growth the fastest?
Golgi
2nd week of proliferative phase
Preeclampsia + siezures
Estradiol > estrone > estriol

49. Which teratoma - mature or immature - is aggresively malignant
Ovary
Immature
The centrioles
Seminoma

50. What is the serum marker for BPH
Corpus luteum cyst
PSA
Slight increase - 1.5 to 2
Lateral invasion can block ureters causing renal failure