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Reproductive

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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1. What changes are seen with total PSA and fraction of free PSA
Milk letdown - uterine contractions?
Corpus luteum cyst
Inc in total - and dec in free fraction
Complete

2. Invasive carcinoma of the cervix is usually caused By what kind of malignancy
Low back pain with increased serum alk phos
Syncytiotrophoblasts of placenta
The ampulla - occurs within 1 day of ovulation
Squamous cell carcinoma

3. inc fluid secondary to incomplete fustion with processus vaginalis
69 xxy
DHT - testosterone - androstenedione
Lateral invasion can block ureters causing renal failure
Hydrocele

4. Short stature - ovarian dysgenesis - shield chest - no barr body - webbing of the neck

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5. What increases risk for endometrial carcinoma
Just prior to ovulation
Unopposed estrogen - obesity - diabetes - HTN - nulliparity - late menopause
Decrease
HPV 16 - 18

6. What is the serum marker for BPH
Fibrosis
PSA
Neoplastic cells block lymphatic drainage
5 alpha reductase - inhibited by finesteride

7. What substances other than inhibin do sertoli cells produce?
Andogren binding protein - anti mullerian hormone
Ovary
Obdurator - exterinal iliac - hypogastic nodes
Estradiol > estrone > estriol

8. What is the expected increase of estradiol and estrone in pregnancy
Right gonadal vein - IVC
DES in utero (DES is a sythetic estrogen)
Meigs syndrome
50 times

9. What does estrogen stimulate in the endometrium
Androgen insensitivity syndrome - 46 XY
Hyperthyroidism - contains functional thyroid tissue
Proliferation
Inhibition LH and FSH

10. What are the functions of oxytocin - maybe
Superficial inguinal lymph nodes
2 months
Milk letdown - uterine contractions?
6

11. What is the main source of energy for spermatozoa
Fructose
Round ligament of the uterus
Oligomenorrhea
Stimulate glandular secretions - and spiral artery development

12. What is the common presentation of metastasis in prostate cancer
Immature
Testosterone
Low back pain with increased serum alk phos
Good - late metastasis

13. What is mortality due to in preeclampsia
Mimics LH
Bowenoid papulosis - carcinoma in situ of the penis
Cerebral hemorrhage and ARDS
Left gonadal vein - left renal vein - IVC

14. What are predisposing factors for placenta previa
Preeclampsia clinical
Weight loss - OCP - gonadotropin analogs - clomiphene - sprinolactone - surgery
Prior c section - multiparity
Just prior to ovulation

15. testicular masses that can be transilluminated
Inhibit cGMP breakdown
Tunica vaginalis lesions
Stimulate glandular secretions - and spiral artery development
Spermatocele

16. What does progesterone do for pregnancy
Increased FSH
6
Maintenance
IV mag sulfate - diazepam

17. What is the best test to confirm menopause
Hyperestrogenism
Increased FSH
Increase in size in pregs - decrease in size meno - estrogen sens
Primary hypogonadism

18. histologic type of fibrocystic with fluid filled - blue dome and ductal dilation
Prior c section - multiparity
Cystic
Fibroadenoma
Right gonadal vein - IVC

19. dx with increased testosterone and inc LH
Defective androgen receptor
Para - aortic lymph nodes
Testosterone - DHT - androstenedione
Menometrorrhagia

20. Dermal lymphatic invasion by breast carcinoma - peu d orange
Prematurity
Inflammatory
51 yo
Fallopian tube

21. What are risk factors for abruptio placentae?
Inc cGMP - smooth muscle relax - vasodltn - proerectile
Smoking - HTN - cocaine
DHT - testosterone - androstenedione
Follicular cyst

22. hyperplasia - not hypertrophy of the prostate gland
Prostate growth - balding - and sebaceous gland activity
BPH
Uterus
Periurethral lobes - lateral and middle

23. What are common causes of hyperestrogenism

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24. What occurs to a fibroadenoma during pregnancy and menstruation and why
Endocervix
Seminiferous tubules - epididymis - vas deferens - ejaculatory ducts - nothing - urethra - penis
Choriocarcinoma
Inc size and tenderness with inc estrogen

25. What are the most common cause of anovluation

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26. Testosterone and estrogen in androgen insensitivity syndrome
Increase (and LH)
Sprinolactone - digitalis - cimetidine - alchohol - ketoconazole
Seminoma
Chromosomal abnormalities

27. what structures supplies the energy to the middle piece (neck)
Fructose
One of the centrioles
Mitochondria
50 times

28. benign painless lump - forms as a result of injury to breast tissue - possible history of trauma
Dysuria - frequency - urgency - low back pain
Broad ligament
Fat necrosis
Intraductal papilloma - breast abscess - mastitis

29. small - mobile - firm breast mass with sharp edges - most common in <25
Fibroadenoma
The semiT and the blood vessels
Invasive ductal
Hypogondadotropic hypogonadism

30. Which cells line the seminiferous tubules and secrete inhibin
Sertoli cells
Tight junctions between sertoli cells
Corpus luteum cyst
Invasive lobular

31. What is the prognosis for seminoma
Myometrial invasion
Hydatidiform moles - choriocarcinoma - gestational trophoblastic tumors
The ampulla - occurs within 1 day of ovulation
Good - late metastasis

32. What is the lymphatic drainage of the proximal 2/3 of the vagina/uterus
Obdurator - exterinal iliac - hypogastic nodes
Testosterone
Menometrorrhagia
Varicocele

33. vaginal carcinoma affecting girls < 4 spindle shaped tumors cells that are desmin positive
Develop both male and female internal genitalia and male external genitalia
Estradiol
Sarcoma botryoides - a rhabdomyosarcoma variant
Asia - Africa - S. America - HPV - lack of circumcision

34. What is the lymphatic drainage of the distal 1/3 of the vagina/scrotum/vulva
Immature
17beta estradiol
Leydig cell tumor
Superficial inguinal lymph nodes

35. How is dyslpasi and carcinoma in situ of the cervix classified
CIN 1 - 2 - 3
Hydrocele
Placenta previa
Para - aortic lymph nodes

36. What is the flaggelum derived from
2nd week of proliferative phase
Testosterone
S aureus
One of the centrioles

37. is fibroadenoma a precursor to breast cancer
Andogren binding protein - anti mullerian hormone
No
Seminoma
Premature ovarian failure (Pof)

38. What is the most common form of male pseudoHerm
Paget's disease - breast abscess
Mimics LH
Spermatogonia (germ cells)
Androgen insensitivity syndrome

39. What complications are associated with polyhydramnios

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40. headache - blurred vision - abdominal pain - edema of face and extremeties - altered mentation - hyperreflexia in pregnancy
Increase in size in pregs - decrease in size meno - estrogen sens
DHT - testosterone - androstenedione
Preeclampsia clinical
Stimulate glandular secretions - and spiral artery development

41. What are the associated risk factors for malignant breast tumors
Just prior to ovulation
Inhibit FSH
Inc estrogen - inc total nunmber of cycles - older age at 1st live birth - obesity
Posterior lobe peripheral zone

42. How does exogenous testosterone create azoospermia
Inhibition of HCG access
E coli
Lobular carcinoma - sclerosing adenosis
Complete

43. <0.5 L of amniotic fluid
Tunica vaginalis lesions
Oligohydramnios
Hirsutism - hot flashes - atrophy of the vagina - osteoporosis - coronary artery disease
Intraductal papilloma

44. In what group are malignant breast tumors most commonly seen
Post menopausal
Testis determining factor
Chocolate cyst
Stimulates testosterone release from leydig cells

45. Red velvety plaques - usually involving the glans - similar to Bowen's
The ampulla - occurs within 1 day of ovulation
Fallopian tube
Erythroplasia of Queyrat - carcinoma in situ of penis
Medullary

46. most common testicular cancer in older men
The anterior pituitary and hypothalamus
Inhibition of HCG access
Testicular lymphoma
Post menopausal

47. What is the single most important prognostic factor for malignant breast tumors
Axillary node involvement
Theca - leutin cysts
Chromosomal abnormalities
Choriocarcinoma

48. Which androgen is responsible for the closing of the epiphyseal plate
Testosterone
Klinefelter's - XXY
Abacterial
Post menopausal

49. Which side is varicocele more common on...
Differentiation of penis - scrotum and prostate
Hydatidiform moles - choriocarcinoma - gestational trophoblastic tumors
Left
Round ligament of the uterus

50. malignant - inc hCG - disordered syncytiotrophoblastic and cytotrophoblastic elements - hematogenous spread
Choriocarcinoma
Dilation and curettage and methotrexate
Complete
Endocervix