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Reproductive

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Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. histologic type of fibrocystic with hyperplasia of breast stroma
Preeclampsia
Sarcoma botryoides - a rhabdomyosarcoma variant
Fibrosis
Smooth muscle

2. malignant - inc hCG - disordered syncytiotrophoblastic and cytotrophoblastic elements - hematogenous spread
Increase
Mucinous cystadenocarcinoma
Inc estrogen - inc total nunmber of cycles - older age at 1st live birth - obesity
Choriocarcinoma

3. What estrogen does the placenta secrete
Fibromas
Prophase
Cerebral hemorrhage and ARDS
Estradiol

4. gynecological tumors from highest incidence to lowest
Obdurator - exterinal iliac - hypogastic nodes
Bowen's dz - carcinoma in situ of the penis
Endometrial > ovarian> cervical (in US)
Chromosomal abnormalities

5. dilated vein in pampiniform plexus - bag of worms
Ligament of the ovary
Hydatidiform mole
Preductal coarctication
Varicocele

6. Arrange the androgens in order of most potent to least potent
Both ovary and testicular tissue present - ambiguous genitals - rare 46 XX - 47XXY
Periurethral lobes - lateral and middle
DHT - testosterone - androstenedione
Complete

7. is fibroadenoma a precursor to breast cancer
Paget cell
Testosterone - DHT - androstenedione
Maintenance
No

8. histological subtype of fibrocystic with inc number of epithelial cell lauers in terminal duct lobule - women over 30
Meigs syndrome
Intraductal papilloma - breast abscess - mastitis
Epithelial hyperplasia
Congenital adrenal hyperplasia - exogenous administration of steroids

9. Benign - looks like bladder
Brenner tumor
Estradiol > estrone > estriol
Peyronie's dz
Tunica vaginalis lesions

10. What serum markers are associated with embyronal carcinoma
Premature ovarian failure (Pof)
Inc AFP and hCG
Preeclampsia clinical
Trophoblasts

11. ovaries plus virilized external genitalia due to excessive and inappropriate exposure to androgenic steroids during early gestation
Spermatogonia (germ cells)
The ampulla - occurs within 1 day of ovulation
Female pseudoHerm
Smoking - HTN - cocaine

12. equivalent to seminoma in the ovary and forms a sheet of uniform cells - marked by hCG and LDH
Corpus luteum - placenta - adrenal cortex - testes
Bowenoid papulosis - carcinoma in situ of the penis
Dysgerminoma
Haploid - 2N - 23 sister chromatids

13. What causes preeclampsia
Placental ischemia due to impaired vasodltn of spiral arteries resulting in increased vasc tone
Dysgerminoma
Mucinous cystadenoma
Develop both male and female internal genitalia and male external genitalia

14. What are the associated risk factors for malignant breast tumors
Fructose
Inc estrogen - inc total nunmber of cycles - older age at 1st live birth - obesity
Hydatidiform mole
Squamo - columnar jxn

15. What structures does testosterone negatively feedback on?
Tubular carcinoma
The anterior pituitary and hypothalamus
Prior c section - multiparity
Fallopian tube

16. What is the main source of energy for spermatozoa
Fructose
CIN 1 - 2 - 3
Polyhydramnios
Mammary duct epithelium or lobular glands

17. What does progesterone do to body temp
Increase
Follicular phase varies - luteal phase is 14
Abruptio placentae
Puberty

18. Which androgen is responsible for the closing of the epiphyseal plate
Testosterone
Fructose
Preductal coarctication
Low progesterone

19. What hematologic condition is associated with abruptio placentae
Diploid - 4N - 46 sister chromatids
Preeclampsia + siezures
Post menopausal bleeding
DIC

20. Which teratoma - mature or immature - is aggresively malignant
Prophase
Brenner tumor
Immature
Low progesterone

21. What are common causes of hyperestrogenism

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22. reinke crystals - androgen producing - gynecomastia in men - precocious puberty in boys - golden brown color
Androgen insensitivity syndrome - 46 XY
Leydig cell tumor
Neoplastic cells block lymphatic drainage
SANS - hypogastric nerve

23. Where is the enlargement found in BPH
Periurethral lobes - lateral and middle
Defective androgen receptor
Feedback inhibition
Prophase

24. What are risk factors for abruptio placentae?
Testosterone
Right gonadal vein - IVC
Osteoblastic in bone
Smoking - HTN - cocaine

25. Where is SCC of the penis more common and What is it associated with
In the 6th decade of life
Sertoli cell tumor
Asia - Africa - S. America - HPV - lack of circumcision
Mucinous cystadenocarcinoma

26. Short stature - ovarian dysgenesis - shield chest - no barr body - webbing of the neck

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27. What does estrogen do to estrogen - LH and progesterone recepotrs
Testosterone secreting tumor - exogenous steroids
Hydatidiform mole
Sprinolactone - digitalis - cimetidine - alchohol - ketoconazole
Upregulation

28. eclampsia
Preeclampsia + siezures
Testosterone
1 week - 2 weeks
17beta estradiol

29. blood from ruptured follicle causing peritoneal irritation that can mimic appendicitis
Cervix
Mittelschmerz syndrome
Severe bleeding iron def anemia - miscarriage
Paget's disease

30. multilocular cyst lined by mucus secreting epi - benign - intestine like
Mucinous cystadenoma
Upregulation
Proliferation
Stimulates sertoli cells to produce ABP and inhibin

31. How does exogenous testosterone create azoospermia
Obdurator - exterinal iliac - hypogastic nodes
2 months
Inhibition of HCG access
GnRH from hypoTh - LH and FSH from ant pituitary

32. pain with or without bleeding - inc in hCG - sudden lower abdominal pain - mistaken for appendicitis
Just prior to ovulation
Prementsrual breast pain and multiple lesions
Ectopic preg
Endocervix

33. in chronic prostatitis is bacterial or abacterial more common
DRE - hard nodule and biopsy
PANS - pelvic nerve
Tunica vaginalis lesions
Abacterial

34. Where does prostatic adenocarcinoma arise from?
Smooth muscle
Inc cGMP - smooth muscle relax - vasodltn - proerectile
Posterior lobe peripheral zone
S aureus

35. What does LH do
Stimulates testosterone release from leydig cells
Hyperestrogenism
Phyllodes tumor
Low back pain with increased serum alk phos

36. A leimyoma is overgrowth of what cell
Inhibit cGMP breakdown
Fibrosis
Follicular phase varies - luteal phase is 14
Smooth muscle

37. endometrium within the myometrium
Tight junctions between sertoli cells
Adenomyosis
Serous cystadenocarcinoma
Tubular carcinoma

38. What forms the blood testis barrier?
Slight increase - 1.5 to 2
Haploid - N - 23 single chromatids
CIN 1 - 2 - 3
Tight junctions between sertoli cells

39. histologic subtype of fibrocystic with inc acini and intralobular fibrosis
Sclerosing adenosis
Epithelial hyperplasia
The anterior pituitary and hypothalamus
Inhibit cGMP breakdown

40. What is the most common pathogen in acute mastitis
Placental insufficiency - bilateral renal agenesis - posterior urethral valves - potter's syndrome
S aureus
Testosterone
Estradiol and possible growth promoting effects of DHT

41. Overexpression of which receptors is common iwht malignant breast tumors
Klinefelter's - XXY
Estrogen/progesterone receptors - erb - B2 - HER2 an EGF receptrs
Malignant in males not in females
Stimulation of secretion - but blocks its action at the breast

42. Large bulky breast mass of connective tissue and cysts with leaf like projections
Testicular lymphoma
Phyllodes tumor
6
Granulosa cell - aromatase - androstenedione - estrogen

43. What is the lymphatic drainage the ovaries/testis
Uterus
Peripheral adipose tissue
Para - aortic lymph nodes
Diploid - 4N - 46 sister chromatids

44. What does the SRY gene do
Blacks
HPV 16 - 18
PSA
Testis determining factor

45. testicular masses that can be transilluminated
Inhibition LH and FSH
Tunica vaginalis lesions
Female pseudoHerm
Theca cell - desmolase - androstenedione

46. common cause of recurrent miscarriage in 1st trimester
Puberty
Complete
Placenta acreta
Chromosomal abnormalities

47. Which system and nerve are responsible for emission
Comedocarcinoma
Alpha1 antagonists - terazosin - tamsulosin - finasteride
SANS - hypogastric nerve
Suspensory ligament of ovaries

48. What is the order of events in the menstrual cycle
Estrogen - LH surge - ovulation - progesterone from CL - menstruation
Corpus luteum - placenta - adrenal cortex - testes
Fertilization 'an egg met a sperm'
Ectopic preg

49. What are the treatments for PCOS
Weight loss - OCP - gonadotropin analogs - clomiphene - sprinolactone - surgery
Squamous cell carcinoma
2 months
Stimulates sertoli cells to produce ABP and inhibin

50. breast abscess - during breast feeding with increased risk of bacterial infxn through cracks in the nipple
Acute mastitis
Para - aortic lymph nodes
Oligohydramnios
Paget's disease - breast abscess