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Reproductive

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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1. What estrogen does the ovary secrete
S aureus
17beta estradiol
Production of a thick cervical mucus
Estradiol and possible growth promoting effects of DHT

2. endometrium within the myometrium
Polymenorrhea
Inhibit FSH
1 week - 2 weeks
Adenomyosis

3. Which cells secrete beta hCG
Suckling - inc oxytocin - prolactin
Trophoblasts
Teratoma
Paget's disease - breast abscess

4. What is the genetic material in the primary oocyte?
PANS - pelvic nerve
DHT - testosterone - androstenedione
Diploid - 4N - 46 sister chromatids
Final stage of spermatogenesis - spermiogenesis - spermatid to spermatozoa

5. What does progesterone do to smooth muscle in the uterus
Post menopausal bleeding
Relaxation
Left
Polyhydramnios

6. large - hyperchromatic syncytiotrophoblasts cells - inc freq theca leutin cysts - develops during pregnancy in mom or baby - marked by hCG
Prior c section - inflammation - placenta previa
Fibroadenoma
Choriocarcinoma
2nd week of proliferative phase

7. disagreement between the phenotypic and gonadal sex
Cardinal ligament
Male pseudoHerm
Phyllodes tumor
Pseudohermaphroditism

8. histo: simple cuboidal epithelium
Increase in size in pregs - decrease in size meno - estrogen sens
Pseudohermaphroditism
Estradiol
Ovary

9. What is the order of events in the menstrual cycle
Cirrhosis - testicular tumor - puberty - old age - klinefelter's syndrome - drugs
Unopposed estrogen - obesity - diabetes - HTN - nulliparity - late menopause
Estrogen - LH surge - ovulation - progesterone from CL - menstruation
History of infertility - salpingitis - ruptured appendix - prior tubal surgery

10. malignancy in ovaries - testis - sacrococcygeal area of young children - yellow friable solid masses with 50% having schiller - duval bodies
Yolk sace - endodermal sinus - tumor
Fallopian tube
Development of genitalia and breast - growth of follicle - hormonal interactions with HPG accesss - and inc transport proteins like SHBG inc HDL and dec LDL
IV mag sulfate - diazepam

11. Connects ovaries to lateral pelvic wall - contains ovarian vessels
Sertoli cells
DIC
Suspensory ligament of ovaries
55-65

12. Prevention of seizures and in preeclampsia
Ovarian > cervical > endometrial
IV mag sulfate - diazepam
Post menopausal
Sclerosing adenosis

13. decreased estrogen - inc FSH - LH - signs of menopause after puberty but before 40
Premature ovarian failure (Pof)
Syncytiotrophoblasts of placenta
Estradiol
Partial

14. What structures does testosterone negatively feedback on?
Theca cell - desmolase - androstenedione
Koilocytitic
The anterior pituitary and hypothalamus
Mucinous cystadenocarcinoma

15. What are the pathologic features of leiosarcoma
Corpus luteum cyst
Brenner tumor
Feedback inhibition
Necrosis - hemorrhage - can protrude from the cervix and bleed - tendency to recur

16. What is the venous drainage of the left ovary/testis?
Inc Ca in - smooth muscle contraction - vasocxn - antierectile
Left gonadal vein - left renal vein - IVC
Insulin resistance
Delivery of fetus

17. testicular atrophy - eunochoid body shape - tall - long extremities - gynecomastia - inactivated X chromosome - dysgenesis of seminiferous tubules - decreased inhibin - abnormal leydig cell function

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18. 20% of ovarian tumors - benign - lined with fallopian tube like epithelium
Fertilization 'an egg met a sperm'
The ampulla - occurs within 1 day of ovulation
Serous cystadenoma
Puberty

19. What is the karyotype of a complete mole
46 xx
Varicocele
Prophase
Diploid - 4N - 46 sister chromatids

20. dx with increased testosterone and inc LH
The anterior pituitary and hypothalamus
Defective androgen receptor
Dilation and curettage and methotrexate
Cardinal ligament

21. Endometriosis is characterized By what clinical picture?
Increase (and LH)
Cyclic bleeding - chocolate cysts - severe menstrual related pain - infertility
Embryonal carcinoma
Invasive ductal

22. A leimyoma is overgrowth of what cell
Haploid - N - 23 single chromatids
Smooth muscle
Round ligament of the uterus
Esophogeal/duodenal atresia - can't swallow - anencephaly

23. What does progesterone do to body temp
Inhibit FSH
Increase
PSA
Brenner tumor

24. What does progesterone do in the endometrium
Left gonadal vein - left renal vein - IVC
Fibroadenoma
Polyhydramnios
Stimulate glandular secretions - and spiral artery development

25. What are risk factors for placenta acreta
Estrogen/progesterone receptors - erb - B2 - HER2 an EGF receptrs
Endocervix
Prior c section - inflammation - placenta previa
Inhibit cGMP breakdown

26. Short stature - ovarian dysgenesis - shield chest - no barr body - webbing of the neck

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27. small follicles filled with eosinphilic secretions
PSA
Premature ovarian failure (Pof)
Fertilization 'an egg met a sperm'
Call exner bodies

28. How many days after fertilization does implantation occur?
Neoplastic cells block lymphatic drainage
Paget's disease - breast abscess
Prior c section - inflammation - placenta previa
6

29. how does BPH present
Choriocarcinoma
Inc freq of urination - nocturia - difficulty starting/stopping urination - dysuria
Stimulate glandular secretions - and spiral artery development
Low progesterone

30. What is the pattern seen in leiomyoma
Placenta previa
Inflammatory
Complete
Whorled pattern of smooth muscle bundles

31. eclampsia
Upregulation
Premature ovarian failure (Pof)
S aureus
Preeclampsia + siezures

32. What does the SRY gene do
Testis determining factor
Inc AFP and hCG
Milk letdown - uterine contractions?
Anovulatory cycles - hormone replacement therapy - PCOS - granulosa cell tumor

33. How long does it take for sperm to fully develop
HPV 16 - 18
Paget's disease
20 to 40
2 months

34. hyperplasia - not hypertrophy of the prostate gland
BPH
Proliferation
Polymenorrhea
Stimulates testosterone release from leydig cells

35. What effect does NE have on smoothe muscle in the erectile tissues
No
Inc Ca in - smooth muscle contraction - vasocxn - antierectile
Female pseudoHerm
Testosterone

36. What is the flaggelum derived from
Broad ligament
Inflammatory
The centrioles
One of the centrioles

37. What complications are associated with polyhydramnios

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38. In What age group are ovarian germ cell tumors most common
Adolescents
Hirsutism - hot flashes - atrophy of the vagina - osteoporosis - coronary artery disease
95%
Turner's XO

39. 90% of ovarian germ cells tumors - contains cells from 2 or 3 germ layers
Teratoma
E coli
Ovary
Broad ligament

40. Where is androstenedione made?
Inhibit cGMP breakdown
Adrenal gland
No
Inc freq of urination - nocturia - difficulty starting/stopping urination - dysuria

41. common cause of recurrent miscarriage in 1st trimester
Syncytiotrophoblasts of placenta
Polymenorrhea
Andogren binding protein - anti mullerian hormone
Chromosomal abnormalities

42. What metastasis is most common with prostatic adenocarcinoma
Sarcoma botryoides - a rhabdomyosarcoma variant
Preeclampsia clinical
Hypogondadotropic hypogonadism
Osteoblastic in bone

43. histologic type of fibrocystic with hyperplasia of breast stroma
Fibrosis
Meigs syndrome
Superficial inguinal lymph nodes
S aureus

44. Where does fertilization most commonly occur?
95%
Esophogeal/duodenal atresia - can't swallow - anencephaly
Defective androgen receptor
The ampulla - occurs within 1 day of ovulation

45. histologic type of fibrocystic with fluid filled - blue dome and ductal dilation
Cystic
Hyperestrogenism
Diploid - 4N - 46 sister chromatids
DES in utero (DES is a sythetic estrogen)

46. What is associated with sclerosing adenosis?
Complete
Calcifications
The centrioles
Klinefelter's - XXY

47. What does estrogen to do prolaction
Mucinous cystadenocarcinoma
Fertilization 'an egg met a sperm'
Stimulation of secretion - but blocks its action at the breast
Sertoli cells

48. benign painless lump - forms as a result of injury to breast tissue - possible history of trauma
Inc freq of urination - nocturia - difficulty starting/stopping urination - dysuria
Fat necrosis
Choriocarcinoma
Abruptio placentae

49. increases in which hormone are associated with BPH
Fructose
Fibrcystic change - ductal cancer
Estradiol and possible growth promoting effects of DHT
Endometrial > ovarian> cervical (in US)

50. What increases risk for endometrial carcinoma
Unopposed estrogen - obesity - diabetes - HTN - nulliparity - late menopause
Fibroadenoma
Theca cell - desmolase - androstenedione
Spermatocele