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Reproductive

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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1. > 35 day cycle
Inc estrogen - inc total nunmber of cycles - older age at 1st live birth - obesity
Bowen's dz - carcinoma in situ of the penis
Low progesterone
Oligomenorrhea

2. Which phase varies and in length and Which is usually 14 days (menstrual cycle)
PSA
Round ligament of the uterus
Follicular phase varies - luteal phase is 14
5 alpha reductase - inhibited by finesteride

3. What is a true hermaphrodite
Neoplastic cells block lymphatic drainage
Both ovary and testicular tissue present - ambiguous genitals - rare 46 XX - 47XXY
Cyclic bleeding - chocolate cysts - severe menstrual related pain - infertility
Bicornute uterus

4. when do primary oocytes begin meiosis I
Preeclampsia + siezures
Teratoma
During fetal life
2nd week of proliferative phase

5. complications of BPH
Klinefelter's - XXY
Paget's disease
Distention and hypertrophy of bladder - hydronephrosis - UTIs - not premalignant
Erythroplasia of Queyrat - carcinoma in situ of penis

6. What hormones regulate sperm creation?
Prementsrual breast pain and multiple lesions
Mittelschmerz syndrome
Abacterial
GnRH from hypoTh - LH and FSH from ant pituitary

7. common cause of recurrent miscarriage in the 1st week
Low progesterone
Medullary
Periurethral lobes - lateral and middle
Koilocytitic

8. Which androgen is responsible for libido
Increased FSH
Immature
Testosterone
Low progesterone

9. large - hyperchromatic syncytiotrophoblasts cells - inc freq theca leutin cysts - develops during pregnancy in mom or baby - marked by hCG
Squamous cell carcinoma
Choriocarcinoma
6
Placental ischemia due to impaired vasodltn of spiral arteries resulting in increased vasc tone

10. histo: stratified squamous epithelium - nonkeratinized
Golgi
Vagina
Chocolate cyst
During fetal life

11. breast path - diseases of the stroma
Fibrosis
Myometrial invasion
Fibroadenoma - phyllodes tumor
Fibroadenoma

12. What increase in estriol is an indicator offetal well being in pregnancy
1000 times
Menopause
2nd week of proliferative phase
Smooth muscle

13. What are the most common tumors in all females?
Myometrial tumors
5 alpha reductase - inhibited by finesteride
Both ovary and testicular tissue present - ambiguous genitals - rare 46 XX - 47XXY
Paget's disease

14. How long does it take for sperm to fully develop
2 months
Increased FSH
Inc estrogen - inc total nunmber of cycles - older age at 1st live birth - obesity
Preeclampsia clinical

15. endometrium within the myometrium
Invasive ductal
Oligohydramnios
Choriocarcinoma
Adenomyosis

16. Between What two phases does the sperm acquire the acrosome - flagellum - and middle piece
Final stage of spermatogenesis - spermiogenesis - spermatid to spermatozoa
Ovary
Placenta acreta
Complete

17. ovaries plus virilized external genitalia due to excessive and inappropriate exposure to androgenic steroids during early gestation
Fibrocystic disease
Dysgerminoma
Fat necrosis
Female pseudoHerm

18. What is the genetic material in the primary oocyte?
Ovarian > cervical > endometrial
Diploid - 4N - 46 sister chromatids
Spermatogonia (germ cells)
Cerebral hemorrhage and ARDS

19. What structures does testosterone negatively feedback on?
46 xx
The anterior pituitary and hypothalamus
Severe bleeding iron def anemia - miscarriage
Polymenorrhea

20. Overexpression of which receptors is common iwht malignant breast tumors
Develop both male and female internal genitalia and male external genitalia
Yolk sace - endodermal sinus - tumor
Placenta previa
Estrogen/progesterone receptors - erb - B2 - HER2 an EGF receptrs

21. How many days after fertilization does implantation occur?
Retrograde mentrual flow or ascending infection
6
Phyllodes tumor
Fibroadenoma - phyllodes tumor

22. Where is SCC of the penis more common and What is it associated with
Fibroadenoma
Polyhydramnios
Asia - Africa - S. America - HPV - lack of circumcision
1000 times

23. Where is androstenedione made?
69 xxy
Placenta previa
Milk letdown - uterine contractions?
Adrenal gland

24. gray - soliarty - crusty plaque - usually on the shaft of the penis or on the scrotum - peak incidence in 5th decade of life - can progress to invasive SCC in < 10% of cases

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25. GI malignancy that metastasizes to ovaries causing a mucin secreting signet cell adenocarcinoma
Krukenburg tumor
Fallopian tube
Corpus luteum - placenta - adrenal cortex - testes
Inc estrogen - inc total nunmber of cycles - older age at 1st live birth - obesity

26. bundles of spindle shaped fibroblasts - pulling sensation in the groin
Cyclic bleeding - chocolate cysts - severe menstrual related pain - infertility
Develop both male and female internal genitalia and male external genitalia
Right gonadal vein - IVC
Fibromas

27. What are the most common cause of anovluation

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28. dx with decreased testosterone - increased LH
Immature
Primary hypogonadism
PANS - pelvic nerve
Relaxation

29. What do leydig cells secrete?
Abacterial
Axillary node involvement
Corpus luteum - placenta - adrenal cortex - testes
Testosterone

30. What is the lymphatic drainage of the distal 1/3 of the vagina/scrotum/vulva
Testosterone
Superficial inguinal lymph nodes
Squamous cell carcinoma
Intraductal papilloma - breast abscess - mastitis

31. What is the presentation of prostatitis
Prematurity
Koilocytitic
No
Dysuria - frequency - urgency - low back pain

32. What is the average age of onset for menopause
Enlarged bilateral cystic ovaries - amenorrhea - infertility - obesity - and hirsutism
51 yo
Leydig cell tumor
Esophogeal/duodenal atresia - can't swallow - anencephaly

33. How is dyslpasi and carcinoma in situ of the cervix classified
CIN 1 - 2 - 3
Bowenoid papulosis - carcinoma in situ of the penis
Estrogen/progesterone receptors - erb - B2 - HER2 an EGF receptrs
Suckling - inc oxytocin - prolactin

34. premature detachment of placenta from implantation site leading to fetal death
Abruptio placentae
Myometrial invasion
Yolk sace - endodermal sinus - tumor
Premature ovarian failure (Pof)

35. When does the secondary oocyte complete meosis II

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36. How does endometrial hyperplasia manifest clinically
Acute mastitis
Post menopausal bleeding
Oligomenorrhea
Follicular phase varies - luteal phase is 14

37. inc fluid secondary to incomplete fustion with processus vaginalis
Bowen's dz - carcinoma in situ of the penis
Hydrocele
Serous cystadenocarcinoma
Dysgerminoma

38. What does estrogen do to estrogen - LH and progesterone recepotrs
Small infiltrating glands with prominent nucleoli
Embryonal carcinoma
Estrogen/progesterone receptors - erb - B2 - HER2 an EGF receptrs
Upregulation

39. inability to convert testosterone to DHT - limited to genetic males - penis at 12
Post menopausal bleeding
Lobular carcinoma - sclerosing adenosis
Testosterone - DHT - androstenedione
5 alpha reductase def

40. histologic subtype of fibrocystic with inc acini and intralobular fibrosis
Sclerosing adenosis
Fructose
Corpus luteum - placenta - adrenal cortex - testes
Mucinous cystadenocarcinoma

41. how can struma ovarri present?
69 xxy
Hyperthyroidism - contains functional thyroid tissue
Trophoblasts
Both ovary and testicular tissue present - ambiguous genitals - rare 46 XX - 47XXY

42. What does estrogen do to FSH and LH
Hydrocele
PSA
Yolk sac - endodermal sinus - tumor
Feedback inhibition

43. gynecological tumors from highest incidence to lowest
Primary hypogonadism
Endometrial > ovarian> cervical (in US)
50 times
Fructose

44. In what phase is meiosis II arrested
Metaphase
Testosterone secreting tumor - exogenous steroids
Complete
Preductal coarctication

45. What is mortality due to in preeclampsia
Comedocarcinoma
Estradiol
Cerebral hemorrhage and ARDS
Osteoblastic in bone

46. What can happen with no sertoli cell or lack of anti mullerian hormone
Develop both male and female internal genitalia and male external genitalia
Endometrial carcinoma
Hemolysis - elevated liver enzymes - low platelets
Pseudohermaphroditism

47. What are the risk factors for endometrial hyperplasia
Anovulatory cycles - hormone replacement therapy - PCOS - granulosa cell tumor
Endometrial carcinoma
Maintenance
Hyperthyroidism - contains functional thyroid tissue

48. testes present with non male external genitals
Male pseudoHerm
Enlarged bilateral cystic ovaries - amenorrhea - infertility - obesity - and hirsutism
Inhibition of HCG access
Menometrorrhagia

49. Risk factors for ectopic pregs
History of infertility - salpingitis - ruptured appendix - prior tubal surgery
Enlarged bilateral cystic ovaries - amenorrhea - infertility - obesity - and hirsutism
Fructose
Testicular lymphoma

50. What changes in the aorta are common in Turner's?
50 times
Weight loss - OCP - gonadotropin analogs - clomiphene - sprinolactone - surgery
Hirsutism - hot flashes - atrophy of the vagina - osteoporosis - coronary artery disease
Preductal coarctication