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Reproductive

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Short stature - ovarian dysgenesis - shield chest - no barr body - webbing of the neck

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2. histological subtype of fibrocystic with inc number of epithelial cell lauers in terminal duct lobule - women over 30
Inhibition LH and FSH
Epithelial hyperplasia
Male pseudoHerm
Cirrhosis - testicular tumor - puberty - old age - klinefelter's syndrome - drugs

3. dx with increased testosterone and dec LH
Inc Ca in - smooth muscle contraction - vasocxn - antierectile
IV mag sulfate - diazepam
Neoplastic cells block lymphatic drainage
Testosterone secreting tumor - exogenous steroids

4. What does the histo show for prostate cancer
Maintenance
Small infiltrating glands with prominent nucleoli
Epithelial hyperplasia
Menopause

5. defect in androgen receptor resulting in normal appearing female - rudimentry vagina - no uterus or uterine tubes
Squamous cell carcinoma
Corpus luteum - placenta - adrenal cortex - testes
Tubular carcinoma
Androgen insensitivity syndrome - 46 XY

6. histo: simple columnar epithelium - pseudostratified tubular glands
DES in utero (DES is a sythetic estrogen)
Bicornute uterus
Uterus
1 week - 2 weeks

7. When are phyllodes tumors most common
Comedocarcinoma
In the 6th decade of life
Testicular lymphoma
Smooth muscle

8. Connects uterus - fallopian tubes and ovaries to pelvic side wall - contains ovaries - fallapian tubes - and round ligaments of uterus
Increased FSH
Broad ligament
Mitochondria
Inc freq of urination - nocturia - difficulty starting/stopping urination - dysuria

9. GI malignancy that metastasizes to ovaries causing a mucin secreting signet cell adenocarcinoma
Paget's disease
Whorled pattern of smooth muscle bundles
Preeclampsia
Krukenburg tumor

10. > 35 day cycle
Corpus luteum - placenta - adrenal cortex - testes
Endometrial carcinoma
Oligomenorrhea
Epithelial hyperplasia

11. predisposing factor to clear cell adenocarcinoma of the vagina
Endometriosis
Suckling - inc oxytocin - prolactin
Testis determining factor
DES in utero (DES is a sythetic estrogen)

12. dx with decreased testosterone - increased LH
Upregulation
Primary hypogonadism
Metaphase
Pseudohermaphroditism

13. breast path - diseases of the stroma
PSA
Fibroadenoma - phyllodes tumor
Testosterone
GnRH from hypoTh - LH and FSH from ant pituitary

14. testes present with non male external genitals
Superficial inguinal lymph nodes
Hemolysis - elevated liver enzymes - low platelets
Inc freq of urination - nocturia - difficulty starting/stopping urination - dysuria
Male pseudoHerm

15. What is the most frequent benign ovarian tumor
Upregulation
Cardinal ligament
Meigs syndrome
Mature teratoma

16. What does gynecomastia result from?
Hyperestrogenism
Fibromas
Bicornute uterus
No

17. inability to convert testosterone to DHT - limited to genetic males - penis at 12
Fertilization 'an egg met a sperm'
Abruptio placentae
5 alpha reductase def
Inhibition of HCG access

18. What percentage of testicular tumors are germ cell
Testosterone secreting tumor - exogenous steroids
95%
Mittelschmerz syndrome
Endometrial carcinoma

19. Which androgens are responsible for the growth spurt of the penis - seminal vesicles - sperm - muscle - RBCs
Fat necrosis
PCOS
Polyhydramnios
Testosterone

20. Which androgen is responsible for differentiation of epididymis - vas deferens - seminal vesicles - internal genitalia (except prostate)
Intraductal papilloma
Testosterone
Stimulate glandular secretions - and spiral artery development
Congenital adrenal hyperplasia - exogenous administration of steroids

21. What does progesterone do to myometrial excitability
Inc AFP and hCG
Multiple sexual partners - also HIV and early sexual intercourse
Decrease
Inhibition LH and FSH

22. Endometriosis is characterized By what clinical picture?
Osteoblastic in bone
Cyclic bleeding - chocolate cysts - severe menstrual related pain - infertility
Necrosis - hemorrhage - can protrude from the cervix and bleed - tendency to recur
Embryonal carcinoma

23. inc AFP - schiller duvel bodies - yellow mucinous
Yolk sac - endodermal sinus - tumor
Leydig cell tumor
One of the centrioles
Squamous cell carcinoma

24. >1.5 -2 L of amniotic fluid
Polyhydramnios
Inc estrogen - inc total nunmber of cycles - older age at 1st live birth - obesity
Abacterial
Trophoblasts

25. What is the source of estrogen after menopause
DES in utero (DES is a sythetic estrogen)
Para - aortic lymph nodes
Complete
Peripheral conversion of androgens

26. What is the expected increase of estradiol and estrone in pregnancy
Haploid - 2N - 23 sister chromatids
Testosterone
50 times
During fetal life

27. What pathologic states cause increases in hCG
Paget's disease - breast abscess
Testosterone
Hydatidiform moles - choriocarcinoma - gestational trophoblastic tumors
History of infertility - salpingitis - ruptured appendix - prior tubal surgery

28. Which androgen is responsible for the deepening of the voice
Hemolysis - elevated liver enzymes - low platelets
Estradiol > estrone > estriol
Testosterone
Male pseudoHerm

29. What is DHT responsible for in early development?
Final stage of spermatogenesis - spermiogenesis - spermatid to spermatozoa
Differentiation of penis - scrotum and prostate
Defective androgen receptor
Tight junctions between sertoli cells

30. benign painless lump - forms as a result of injury to breast tissue - possible history of trauma
2 months
Inhibit cGMP breakdown
Fat necrosis
Cystic

31. Which phase varies and in length and Which is usually 14 days (menstrual cycle)
Increase (and LH)
Dysuria - frequency - urgency - low back pain
SANS - hypogastric nerve
Follicular phase varies - luteal phase is 14

32. What is mortality due to in preeclampsia
2nd week of proliferative phase
Cerebral hemorrhage and ARDS
Placenta acreta
Inc estrogen - inc total nunmber of cycles - older age at 1st live birth - obesity

33. What is the treatment for hydatidiform mole
Dilation and curettage and methotrexate
Mucinous cystadenocarcinoma
Cerebral hemorrhage and ARDS
Ectopic preg

34. Bent penis due to acquired fibrous tissue formation

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35. What are the treatments for PCOS
Testosterone secreting tumor - exogenous steroids
Yolk sac - endodermal sinus - tumor
2 months
Weight loss - OCP - gonadotropin analogs - clomiphene - sprinolactone - surgery

36. tumor is fleshy - cellular - with a lymphocytic infiltrate - good prognosis
55-65
Testosterone secreting tumor - exogenous steroids
Medullary
Primary hypogonadism

37. 90% of ovarian germ cells tumors - contains cells from 2 or 3 germ layers
Teratoma
Premature ovarian failure (Pof)
S aureus
Granulosa cell tumor

38. What are risk factors for abruptio placentae?
Smoking - HTN - cocaine
Right gonadal vein - IVC
Preeclampsia clinical
Estrogen - LH surge - ovulation - progesterone from CL - menstruation

39. In What age group are ovarian germ cell tumors most common
Adolescents
Fibroadenoma - phyllodes tumor
No
Intraductal papilloma - breast abscess - mastitis

40. Overexpression of which receptors is common iwht malignant breast tumors
Estrogen/progesterone receptors - erb - B2 - HER2 an EGF receptrs
The anterior pituitary and hypothalamus
Obdurator - exterinal iliac - hypogastic nodes
Immature

41. What common valvular abnormality is common in Turner's
Stimulation of secretion - but blocks its action at the breast
Inc risk for carcinoma
Aortic bicuspid valve
Testosterone

42. What is a potential complication of endometrial hyperplasia
Endometrial carcinoma
Andogren binding protein - anti mullerian hormone
Ectocervix
Choriocarcinoma

43. A leimyoma is overgrowth of what cell
Leydig cell tumor
Smooth muscle
PCOS
Inhibit cGMP breakdown

44. What is the prognosis for seminoma
Feedback inhibition
Trophoblasts
Estradiol
Good - late metastasis

45. When does endometiral carcinoma usually occur
Both ovary and testicular tissue present - ambiguous genitals - rare 46 XX - 47XXY
Fibroadenoma
Decrease
55-65

46. large cells in epidermis with clear halo
Cystic
Retrograde mentrual flow or ascending infection
Slight increase - 1.5 to 2
Paget cell

47. What is the lymphatic drainage the ovaries/testis
CIN 1 - 2 - 3
Peyronie's dz
Acute mastitis
Para - aortic lymph nodes

48. dx with decreased testosterone and decreased LH
Maintenance
Hypogondadotropic hypogonadism
Choriocarcinoma
Koilocytitic

49. histologic type of fibrocystic with hyperplasia of breast stroma
Estrogen - LH surge - ovulation - progesterone from CL - menstruation
50 times
Fibrosis
Polyhydramnios

50. What does increasing estrogen do to GnRH receptors on ant pit - and What does this lead to...
Inc freq of urination - nocturia - difficulty starting/stopping urination - dysuria
Upregulation - LH surge - ovulation
Granulosa cell tumor
Teratoma