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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. B1 thiamine - B2 riboflavin - B3 niacin - B6 pyridoxine - B12 cobalamin - C ascorbic acid - D calciferol - E a::tocopherol






2. Manifestation of lymphplasmocytic lymphoma - B cell neoplasm






3. Deficient sphingomyelinase - accumulation of sphingomyelin in phagocytes - foamy histiocytes in liver - spleen - lymph nodes - skin - hepatosplenomegaly - anemia fever - occasional neuro degeneration - half have cherry red spot macula






4. Philadelphia chromosome - CML bcr abl fusion c - abl on 9 - bcr on 22






5. Seen in CLL - leukemic B- cells that are fragile






6. Vaginal epithelial cell with stippled appearance due to adherent coccobacilli






7. Polyostotic fibrous dysplasia - precocious puberty - caf






8. Similar to Dubin Johnson with no black liver






9. Eczematoid lesion of nipple areola - large cells with clear 'halo like' area - invade epidermis - underlying ductal CA






10. Ovarian tumor resembling bladder transitional epith






11. Urethritis - conjunctivitis - arthritis - associated with venereal or intestinal infection






12. Diffuse nodular diabetic glomerulosclerosis






13. Hamartomatous polyps in colon and small intest - freckles on lips - hands - genitalia - higher incidence of adeno CA of colon and other malignancies - stomach - breast - ovaries






14. Superclavicular lymph node identifying metastatic stomach CA






15. Autoimmune hypothyroid - hurthle cells common






16. Aka congenital megacolon - dilation of colon due to absence of ganglion cells






17. Aka trisomy 13 - mental retardation - microcephaly - micropthalmia - brain abnormalities - cleft lip/palate - polydactyly - rockerbottom feet - congenital heart dx






18. Tennis racket shaped cytoplasmic inclusion seen in langerhans cells (so also seen in langerhan cell histiocytosis)






19. Pituitary insufficiency post - partum - low TSH ACTH






20. Associated with 90% cases of ankylosing spondylitis - common in rheumatoid arthritis






21. Hereditary nephritis associated with nerve deafness and ocular disorders - mutation in gene for the a5 chain of type IV collagen






22. Seen in papillary thyroid CA






23. Hemorrhagic urticaria of extensor surgaces of arms - legs - and buttocks - with fever - arthralgias - and GI renal involvement similar to IgA nephropathy - associated with URIs






24. Malignant lymphoma with features resembling inflammatory disorder - young men - Reed Sternburg cells






25. Catastrophic adrenal insuff and vascular collapse - hemorrhagic necrosis of adrenal cortex






26. Paracentric inversion or translocation with 17 associated with papillary thyroid CA






27. Aka angiokeratoma corporis diffusum universal - deficient a::galactosidase A - accumulate ceramide trihexoside - skin lesions angiokeratomas - fever - burning pain in extremities - cardiovascular and cerebrovascular involvement - death as adult by re






28. Aka IgA nephropathy - deposition of IgA in mesangium - benign recurrent hematuria in kids following infection






29. Aka pituitary cachexia - generalized panhypopituitarism






30. Hemangioblastoma or cavernous hemangioma of cerebellum - brainstem or retina - adenomas - cysts in liver - kidney - pancreas - and other organs - increased renal cell CA - gene = short arm of chromosome 3






31. Mucopolysaccharidosis - deficient a L iduronidase - accumulations of heparin sulfate and dermatan sulfate in heart - brain - liver - and other organs - progressive - hepatosplenomagaly - dwarfism - gargoyle - like facies - stubby fingers - corneal cl






32. Autosomal recessive - hepatitis - accumulation of copper due to transport problem - low ceruloplasmin seen - kayser fleischer rings in eyes






33. Aka infantile progressive spinal muscular atrophy - autosomal recessive - LMN disease - infants






34. Paternal transmission del (15)(q11q13) - hypogonad - hypotonia - mental retardation - behavior probs - uncrontrolled appetite






35. = MEN1






36. Osteophytes at PIP joints






37. Follicular lymphoma IG heavy chain on 14 - bcl -2 oncogene on 18






38. Aka velocardiofacial syndrome and CATCH 22 syndrome - micro deletion of 22q11 - Cardiac abnormalities - Abnormal facies - T cell deficit due to thymic hypoplasia - Cleft palate - Hypocalcemia due to hypoparathyroidism - from poor development of 3rd a






39. Primary aldosteronism






40. Seen in urine of patients with multiple myeloma - Ig light chain either k or l






41. Metastatic stomach CA to ovary






42. Aka acute disseminated langerhans cell histiocytosis - aggressive - usually fatal - kids hepatosplenomegaly - LAD - pancytopenia - pulmonary involvement - recurrent infections






43. Development of large pituitary adenomas following bilat adrenalectomy






44. Deficient a1 -4 glucosidase - accumulation of glycogen in liver - heart - skeletal muscle - cardiomegaly - muscle hypotonia - spelnomegaly - intractable hypoglycemia - death from cardiorespiratory failure before age 3






45. B Thalassemia major






46. Autoimmune thyroiditis - hyperthyroid - exophthalmos - increased in HLA DR3 and HLA B8 pos people






47. Acute inflammatory demyelinating dx primarily involving peripheral nerves






48. Autosomal recessive - neutropenia - albinism - cranial and peripheral neuropathy - tendency to develop repeated infections - abnormal WBCs (abnormal mictotubul formation and large cytoplasmic granules = lysosomes)






49. Also seen in urine of MM - stacks of RBCs - will have high ESR






50. Port wine stain on face - ipsilateral glaucoma - vascular lesions of ocular choroidal tissue - extensive hemangiomatous involvement of meninges






Can you answer 50 questions in 15 minutes?



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