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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. On lymph node biopsy - seen with Burkitt lymphoma






2. Tumor suppressor common in familial polyposis coli and adenoCA of colon as well as other tumors






3. Modest elevated serum unconj bilirubin - due to decreased uptake by liver cells and reduced activity of glucuronyl transferase






4. This comes in a wet variety and a dry one - they are both Vit B1 thiamine deficiency






5. B1 thiamine - B2 riboflavin - B3 niacin - B6 pyridoxine - B12 cobalamin - C ascorbic acid - D calciferol - E a::tocopherol






6. Mucopolysaccharidosis - deficient a L iduronidase - accumulations of heparin sulfate and dermatan sulfate in heart - brain - liver - and other organs - progressive - hepatosplenomagaly - dwarfism - gargoyle - like facies - stubby fingers - corneal cl






7. Unknown etiology - necrotizing granulomatous vasculitis of small to medium sized vessels of the respiratory tract - kidneys - and other organs - circulating C- ANCAs






8. Also seen in urine of MM - stacks of RBCs - will have high ESR






9. Myc :: neuroblastoma amplicatiion correlates inversely with degree of differentiation






10. Defective in x- linked brutons agammaglobulinemia - B- cell tyrosine kinase






11. Located on xsome 6 - mutation here = hereditary hemochromatosis






12. Hamartomatous polyps in colon and small intest - freckles on lips - hands - genitalia - higher incidence of adeno CA of colon and other malignancies - stomach - breast - ovaries






13. Vasosmasm of small vessels - most often in fingers - seen with autoimmune dx like SLE - scleroderma and others (R in CREST) - recurrent vasospasm - always secondary to underlying disorder






14. Hemihypertrophy - macroglossia - organomegaly - neonatal hypoglycemia - various embryonal tumors - deleted WT 2 gene






15. Aka velocardiofacial syndrome and CATCH 22 syndrome - micro deletion of 22q11 - Cardiac abnormalities - Abnormal facies - T cell deficit due to thymic hypoplasia - Cleft palate - Hypocalcemia due to hypoparathyroidism - from poor development of 3rd a






16. Aka chronic progressive histiocytosis - not as bad as Letterer Siwe






17. Pigmented iris hamartoma seen in neurofibromatosis






18. Catastrophic adrenal insuff and vascular collapse - hemorrhagic necrosis of adrenal cortex






19. Peripheral neuropathy - atrophy of muscles - wet - high output cardiac failure - DCM - AV shunting - hypervolemia






20. Area of focal interstitial myocardial inflammation characterized by fragmented collagen and fibrinoid material - by large cells (Anitschkow myocytes) and occasional multinucleated giant cells (Aschoff cells)






21. Gene product inhibits apoptosis






22. Malignant lymphoma with features resembling inflammatory disorder - young men - Reed Sternburg cells






23. Infectious disorder - caused postencephalitic parkinsonism






24. Autosomal recessive - hepatitis - accumulation of copper due to transport problem - low ceruloplasmin seen - kayser fleischer rings in eyes






25. = MEN2a






26. Severe unconj hyperbilirubinemia due to deficient glucuronyl transferase






27. Mutation here causes pseudohypoparathyroidism






28. Epithelial cells with eosinophilc granular cytoplasm seen in hashimoto






29. Aka neurofibromatosis - neurofibromas in skin - schwannomas of CN VIII - caf






30. Aggressive B- cell lymphoma - EBV - starry sky appearance - c myc






31. Superclavicular lymph node identifying metastatic stomach CA






32. Deficient a1 -4 glucosidase - accumulation of glycogen in liver - heart - skeletal muscle - cardiomegaly - muscle hypotonia - spelnomegaly - intractable hypoglycemia - death from cardiorespiratory failure before age 3






33. Aka IgA nephropathy - deposition of IgA in mesangium - benign recurrent hematuria in kids following infection






34. Hereditary nephritis associated with nerve deafness and ocular disorders - mutation in gene for the a5 chain of type IV collagen






35. Similar to Hurler - deficient L iduronosulfate sulfatase - accumulations of heparin sulfate and dermatan sulfate - hepatospenomegaly - micrognathia - retinal degeneration - joint stiffness - mental retardation - cardiac lesions






36. Pituitary insufficiency post - partum - low TSH ACTH






37. Similar to paget breast - sometimes related to underlying adenoCA of sweat glands






38. Associated with breast alone (isn't one of these associated with prostate? Check)






39. Deficient debranching enzyme amylo -1 -6- glucosidase - glycogen in liver - heart - skeletal muscle - stunted growth - hepatomegaly - hypoglycemia






40. Eosinophilic intracytoplasmic inclusions in hippocampus and purkinje cells seen in rabies infection






41. Aka pulseless dx - inflammation and stenosis of medium and large sized arteries - often aortic arch thus aortic arch syndrome






42. Single erythematous plaque on shaft of penis or scrotum






43. Autosomal recessive - unusually large platelets - lack of 'GPIb IX V'






44. Binucleated or multinucleated giant cell seen in Hodgkin dx






45. Oligohydramnios causes fetus to be smashed






46. Small round eosinophilic masses found in dieing hepatocytes often containing chromatin remnants seen in viral hepatitis






47. Associated with papillary thyroid CA






48. Aka angiokeratoma corporis diffusum universal - deficient a::galactosidase A - accumulate ceramide trihexoside - skin lesions angiokeratomas - fever - burning pain in extremities - cardiovascular and cerebrovascular involvement - death as adult by re






49. Deficient fibrillin (constituent of microfibrils) - arachnodactyly - ectopia lentis - aortic aneurysm - mitral valve prolapsed






50. Paternal transmission del (15)(q11q13) - hypogonad - hypotonia - mental retardation - behavior probs - uncrontrolled appetite