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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Abnormal WT 1 gene - intersexual disorders - nephropathy - wilms tumor






2. Small follicles filled with eosinophilic secretion - diagnostic feature of granulose cell tumor






3. Aka acute disseminated langerhans cell histiocytosis - aggressive - usually fatal - kids hepatosplenomegaly - LAD - pancytopenia - pulmonary involvement - recurrent infections






4. Also seen in urine of MM - stacks of RBCs - will have high ESR






5. Aka allergic granulomatous angiitis - necrotizing vasculitis - variant of polyarteritis nodosa - involves pulmonary vasculature - peripheral eosinophilia - and asthma






6. Associated with papillary thyroid CA






7. Adenomatous polyps with tumors of CNS






8. Aka osteopetrosis - marble bone dx - dense skeleton - failure of osteoclastic activity






9. 2/neu :: oncogene (aka c - erbB2) - in breast cancer = poor prognosis






10. Single erythematous plaque on shaft of penis or scrotum






11. Modest elevated serum unconj bilirubin - due to decreased uptake by liver cells and reduced activity of glucuronyl transferase






12. Triad of ovarian fibroma - ascites - hydrothorax






13. Osteophytes at DIP joints






14. Aka pituitary cachexia - generalized panhypopituitarism






15. Clear cell renal tumor seen in kids






16. Development of large pituitary adenomas following bilat adrenalectomy






17. = MEN2a






18. Nuclei arranged in horseshoe - shaped pattern about periphery of cell - characteristic of but not specific for granulomatous TB (as opposed to a foreign body giant cell that has scattered nuclei)






19. Acute inflammatory demyelinating dx primarily involving peripheral nerves






20. Aka velocardiofacial syndrome and CATCH 22 syndrome - micro deletion of 22q11 - Cardiac abnormalities - Abnormal facies - T cell deficit due to thymic hypoplasia - Cleft palate - Hypocalcemia due to hypoparathyroidism - from poor development of 3rd a






21. Philadelphia chromosome - CML bcr abl fusion c - abl on 9 - bcr on 22






22. Burkitts c::myc is on 8 - IG heavy chain is on 14






23. Seen in granuloma inguinale - multiple organisms filling large histiocytes






24. Deficient a1 -4 glucosidase - accumulation of glycogen in liver - heart - skeletal muscle - cardiomegaly - muscle hypotonia - spelnomegaly - intractable hypoglycemia - death from cardiorespiratory failure before age 3






25. Transloc seen in ewing sarcoma






26. Mesangial matrix material acculmulations seen in nodular glomerulosclerosis seen in diabetic nephropathy






27. Small round blue cell tumor of bone - long bones - kids - 11:22 transloc






28. Hemangioblastoma or cavernous hemangioma of cerebellum - brainstem or retina - adenomas - cysts in liver - kidney - pancreas - and other organs - increased renal cell CA - gene = short arm of chromosome 3






29. Retinoblastoma on chromosome 13






30. Binucleated or multinucleated giant cell seen in Hodgkin dx






31. Mucopolysaccharidosis - deficient a L iduronidase - accumulations of heparin sulfate and dermatan sulfate in heart - brain - liver - and other organs - progressive - hepatosplenomagaly - dwarfism - gargoyle - like facies - stubby fingers - corneal cl






32. Thyroid replacement by fibrous tissue - unkown origin - mimics






33. Occurs in SLE - small vegitations on either or both surfaces of valves






34. Tumor suppressor mutated in breast and ovary






35. Radiologic appearance of periostium in bone tumors






36. Seen in hyperacute rejection - = acute inflammation - fibrinoid necrosis of small vessels - and extensive thrombosis






37. Deficient hexosaminidase A - GM2 ganglioside accumulation - especially in neurons - CNS degeneration - mental/motor deterioration - blindness - cherry red spot on macula - death by 4 years of age






38. Ovarian tumor resembling bladder transitional epith






39. 45 XO - female hypogonadism - hypothyroid - short - webbed neck - 1* amenorrhea p52






40. Severe unconj hyperbilirubinemia due to deficient glucuronyl transferase






41. Combination of hyperthyroidism - nodular goiter - absence of exophthalmos






42. Seen in insulinoma - episodic hyperinsulinemia and hypoglycemia - CNS dysfunction - reversal of CNS probs with administration of glucose






43. Similar to Dubin Johnson with no black liver






44. Aspirin toxicity seen in kids after acute febrile viral dx - microvesicular fatty change in liver and encephalopathy






45. Catastrophic adrenal insuff and vascular collapse - hemorrhagic necrosis of adrenal cortex






46. Similar to Hurler - deficient L iduronosulfate sulfatase - accumulations of heparin sulfate and dermatan sulfate - hepatospenomegaly - micrognathia - retinal degeneration - joint stiffness - mental retardation - cardiac lesions






47. Autosomal dominant - fatal - progressive degeneration of striatum and frontal cortex with neuronal depletion and gliosis






48. Associated with breast alone (isn't one of these associated with prostate? Check)






49. Primary adrenal failure






50. Myc :: neuroblastoma amplicatiion correlates inversely with degree of differentiation