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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Seen in papillary thyroid CA






2. Deficient debranching enzyme amylo -1 -6- glucosidase - glycogen in liver - heart - skeletal muscle - stunted growth - hepatomegaly - hypoglycemia






3. Peripheral neuropathy - atrophy of muscles - wet - high output cardiac failure - DCM - AV shunting - hypervolemia






4. Protooncogene mutated in medulary thyroid CA (MENII)






5. Intracytoplasmic proximal dentritic eosinophilic inclusions consisting of actin seen in Alzheimers






6. Downward displacement of cerebellar tonsils and medulla through foramen magnum






7. Aka osteitis deformans - increased osteoclastic and osteoblastic activity






8. This comes in a wet variety and a dry one - they are both Vit B1 thiamine deficiency






9. Autosomal recessive - hepatitis - accumulation of copper due to transport problem - low ceruloplasmin seen - kayser fleischer rings in eyes






10. Aka hereditary hemorrhagic telangectasia - telangectasias in skin and mucous membranes - epistaxis - GI bleeds






11. Aka chronic progressive histiocytosis - not as bad as Letterer Siwe






12. Associated with 90% cases of ankylosing spondylitis - common in rheumatoid arthritis






13. Pigmented iris hamartoma seen in neurofibromatosis






14. Epithelial cells with eosinophilc granular cytoplasm seen in hashimoto






15. Mutation = paroxysmal nocturnal hemoglobinuria






16. Catastrophic adrenal insuff and vascular collapse - hemorrhagic necrosis of adrenal cortex






17. Manifestation of lymphplasmocytic lymphoma - B cell neoplasm






18. Aka lentigo maligna - precursor to lentigo maligna melanoma






19. Aka velocardiofacial syndrome and CATCH 22 syndrome - micro deletion of 22q11 - Cardiac abnormalities - Abnormal facies - T cell deficit due to thymic hypoplasia - Cleft palate - Hypocalcemia due to hypoparathyroidism - from poor development of 3rd a






20. Oncogenes that code for p21 proteins which are membrane signalers






21. Aka trisomy 18 - mental retardation - prominent occiput - micrognathia (small jaw) - low::set ears - rocker::bottom feet - finger deformities - congenital heart dx






22. Mucopolysaccharidosis - deficient a L iduronidase - accumulations of heparin sulfate and dermatan sulfate in heart - brain - liver - and other organs - progressive - hepatosplenomagaly - dwarfism - gargoyle - like facies - stubby fingers - corneal cl






23. Aka infantile progressive spinal muscular atrophy - autosomal recessive - LMN disease - infants






24. = MEN1






25. Triad of ovarian fibroma - ascites - hydrothorax






26. Vasosmasm of small vessels - most often in fingers - seen with autoimmune dx like SLE - scleroderma and others (R in CREST) - recurrent vasospasm - always secondary to underlying disorder






27. B1 thiamine - B2 riboflavin - B3 niacin - B6 pyridoxine - B12 cobalamin - C ascorbic acid - D calciferol - E a::tocopherol






28. Aka pituitary cachexia - generalized panhypopituitarism






29. Single erythematous plaque on shaft of penis or scrotum






30. Similar to Hurler - deficient L iduronosulfate sulfatase - accumulations of heparin sulfate and dermatan sulfate - hepatospenomegaly - micrognathia - retinal degeneration - joint stiffness - mental retardation - cardiac lesions






31. Malignant lymphoma with features resembling inflammatory disorder - young men - Reed Sternburg cells






32. Acute promyelocytic leukemia PML gene on 15 and RARa on 17






33. Deficient a1 -4 glucosidase - accumulation of glycogen in liver - heart - skeletal muscle - cardiomegaly - muscle hypotonia - spelnomegaly - intractable hypoglycemia - death from cardiorespiratory failure before age 3






34. Autosomal dominant - fatal - progressive degeneration of striatum and frontal cortex with neuronal depletion and gliosis






35. Mucinous cell - characteristic of stomach CA met to ovary (krukenberg tumor)






36. Aka IgA nephropathy - deposition of IgA in mesangium - benign recurrent hematuria in kids following infection






37. Myc :: neuroblastoma amplicatiion correlates inversely with degree of differentiation






38. Deficient fibrillin (constituent of microfibrils) - arachnodactyly - ectopia lentis - aortic aneurysm - mitral valve prolapsed






39. Deficient sphingomyelinase - accumulation of sphingomyelin in phagocytes - foamy histiocytes in liver - spleen - lymph nodes - skin - hepatosplenomegaly - anemia fever - occasional neuro degeneration - half have cherry red spot macula






40. Nystagmus - intention tremor - scanning speech - seen in MS






41. Mutation here causes pseudohypoparathyroidism






42. Development of large pituitary adenomas following bilat adrenalectomy






43. Tumor suppressor mutated in wilms tumor






44. Osteophytes at PIP joints






45. Associated with Wegener granulomatosis






46. Lots of tumors - breast CA - soft tissue sarc - brain tumors - leukemias - has loss of p53 tumor suppressor gene






47. Dysplastic cell seen in HPV






48. Seen in insulinoma - episodic hyperinsulinemia and hypoglycemia - CNS dysfunction - reversal of CNS probs with administration of glucose






49. Aka trisomy 13 - mental retardation - microcephaly - micropthalmia - brain abnormalities - cleft lip/palate - polydactyly - rockerbottom feet - congenital heart dx






50. Aka superior sulcus tumor - seen in bronchogenic CA - often with Horner's







Sorry!:) No result found.

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