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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Hemorrhagic urticaria of extensor surgaces of arms - legs - and buttocks - with fever - arthralgias - and GI renal involvement similar to IgA nephropathy - associated with URIs






2. Epithelial cells with eosinophilc granular cytoplasm seen in hashimoto






3. Associated with breast alone (isn't one of these associated with prostate? Check)






4. Seen in insulinoma - episodic hyperinsulinemia and hypoglycemia - CNS dysfunction - reversal of CNS probs with administration of glucose






5. Associated with papillary thyroid CA






6. Sphingomyelin containing phagocytes seen in Niemman::Pick dx in liver - spleen - lymph nodes and skin






7. Aka velocardiofacial syndrome and CATCH 22 syndrome - micro deletion of 22q11 - Cardiac abnormalities - Abnormal facies - T cell deficit due to thymic hypoplasia - Cleft palate - Hypocalcemia due to hypoparathyroidism - from poor development of 3rd a






8. Mucinous cell - characteristic of stomach CA met to ovary (krukenberg tumor)






9. Acute inflammatory demyelinating dx primarily involving peripheral nerves






10. Deficient glucose -6- phosphatase - accumulation of glycogen in liver and kidney - hepatomegaly - hypoglycemia






11. Eczematoid lesion of nipple areola - large cells with clear 'halo like' area - invade epidermis - underlying ductal CA






12. Follicular lymphoma IG heavy chain on 14 - bcl -2 oncogene on 18






13. Aka infantile progressive spinal muscular atrophy - autosomal recessive - LMN disease - infants






14. DsDNA antibodies and Sm Smith antigen = highly specific for SLE






15. Autoimmune thyroiditis - hyperthyroid - exophthalmos - increased in HLA DR3 and HLA B8 pos people






16. Autosomal dominant - numerous adenomatous polyps along with osteomas and soft tissue tumors






17. Autosomal recessive - unusually large platelets - lack of 'GPIb IX V'






18. Aneurysm at small artery bifurcations






19. Thiamine deficiency - cerebral dysfunction - aka alcoholic encephalopathy - hemorrhagic lesions in the mamillary bodies - confusion - ataxia - ophthalmoplegia - and memory loss plus confabulation p 105 and p115






20. Aspirin toxicity seen in kids after acute febrile viral dx - microvesicular fatty change in liver and encephalopathy






21. Aka antiglomerular basement membrane dx - antibodies against alveolar and glomerular basement membranes - linear immunoflorescence






22. Triad of ovarian fibroma - ascites - hydrothorax






23. Variant of rheumatoid arthritis - splenmegally - neutropenia - RA






24. Small round blue cell tumor of bone - long bones - kids - 11:22 transloc






25. Tumor suppressor mutated in wilms tumor






26. Aka polycystic ovary syndrome - young women - amenorrhea - infertility - obesity - hirsutism






27. Aka chronic progressive histiocytosis - not as bad as Letterer Siwe






28. Intra::alveolar hemosiderin - laden macrophages caused by RBCs from capillary rupture 2* to pulmonary HTN






29. Hereditary nephritis associated with nerve deafness and ocular disorders - mutation in gene for the a5 chain of type IV collagen






30. Pigmented iris hamartoma seen in neurofibromatosis






31. Gene product inhibits apoptosis






32. Chromosome 19 - allele common in alzheimers






33. Port wine stain on face - ipsilateral glaucoma - vascular lesions of ocular choroidal tissue - extensive hemangiomatous involvement of meninges






34. Severe unconj hyperbilirubinemia due to deficient glucuronyl transferase






35. Associated with 90% cases of ankylosing spondylitis - common in rheumatoid arthritis






36. B Thalassemia major






37. Variant of rheumatoid arthritis - aka juvenile rheumatoid arthritis






38. This comes in a wet variety and a dry one - they are both Vit B1 thiamine deficiency






39. X linked - absence of plasma cells and serum immunoglobulins - cell mediated immunity still ok - no germinal centers - recurrent bacterial infections - resistances to fungal and viral still - btk gene defect






40. Mutation = paroxysmal nocturnal hemoglobinuria






41. Transloc seen in ewing sarcoma






42. Thyroid replacement by fibrous tissue - unkown origin - mimics






43. Aka superior sulcus tumor - seen in bronchogenic CA - often with Horner's






44. Different in that it is the primary disorder - recurrent vasospasm of small arteries and venules - pallor - cyanosis - fingers and toes - young healthy women






45. Metastatic stomach CA to ovary






46. Development of large pituitary adenomas following bilat adrenalectomy






47. Protooncogene mutated in medulary thyroid CA (MENII)






48. Downward displacement of cerebellar tonsils and medulla through foramen magnum






49. Mutation here causes pseudohypoparathyroidism






50. Deficient muscle phosphorylase - glycogen in skeletal muscle - cramps with exertion