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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Occurs in SLE - small vegitations on either or both surfaces of valves






2. Thiamine deficiency - cerebral dysfunction - aka alcoholic encephalopathy - hemorrhagic lesions in the mamillary bodies - confusion - ataxia - ophthalmoplegia - and memory loss plus confabulation p 105 and p115






3. Unknown etiology - necrotizing granulomatous vasculitis of small to medium sized vessels of the respiratory tract - kidneys - and other organs - circulating C- ANCAs






4. Materal transmission del(15)(q11q13) - aka happy puppet syndrome - mental retardation - ataxia - seizures - inappropriate laughter






5. Similar to Hurler - deficient L iduronosulfate sulfatase - accumulations of heparin sulfate and dermatan sulfate - hepatospenomegaly - micrognathia - retinal degeneration - joint stiffness - mental retardation - cardiac lesions






6. Transloc seen in ewing sarcoma






7. Autosomal recessive - unusually large platelets - lack of 'GPIb IX V'






8. Combination of hyperthyroidism - nodular goiter - absence of exophthalmos






9. At least 2 X and one Y - hypogonadism - tall - gynecomastia - low testosterone - high pituitary gonadotropins - infertility -






10. Osteophytes at DIP joints






11. Asbestosis - yellow - brown - rod shaped body with clubbed ends - stain with Prussian blue






12. Aka angiokeratoma corporis diffusum universal - deficient a::galactosidase A - accumulate ceramide trihexoside - skin lesions angiokeratomas - fever - burning pain in extremities - cardiovascular and cerebrovascular involvement - death as adult by re






13. Autosomal dominant - numerous adenomatous polyps along with osteomas and soft tissue tumors






14. Pituitary insufficiency post - partum - low TSH ACTH






15. Aka osteopetrosis - marble bone dx - dense skeleton - failure of osteoclastic activity






16. Autoimmune thyroiditis - hyperthyroid - exophthalmos - increased in HLA DR3 and HLA B8 pos people






17. Minute neutrophilic abscesses found within parakeratotic stratum corneum in psoriasis






18. Primary adrenal failure






19. Aka congenital megacolon - dilation of colon due to absence of ganglion cells






20. Dysplastic cell seen in HPV






21. Tumor suppressor common in familial polyposis coli and adenoCA of colon as well as other tumors






22. Similar to Dubin Johnson with no black liver






23. Follicular lymphoma IG heavy chain on 14 - bcl -2 oncogene on 18






24. Defective in x- linked brutons agammaglobulinemia - B- cell tyrosine kinase






25. X linked - aka immunodeficiency with thrombocytopenia and eczema - total immunoglobulins often normal - recurrent infections






26. Diffuse nodular diabetic glomerulosclerosis






27. Primary aldosteronism






28. On lymph node biopsy - seen with Burkitt lymphoma






29. Aspirin toxicity seen in kids after acute febrile viral dx - microvesicular fatty change in liver and encephalopathy






30. Seen in Down synd - small white spots on periphery of iris






31. Aka neurofibromatosis - neurofibromas in skin - schwannomas of CN VIII - caf






32. Seen in urine of patients with multiple myeloma - Ig light chain either k or l






33. Intracytoplasmic inclusions seen in leydig cell tumors p283






34. Adenomatous polyps with tumors of CNS






35. Aka lentigo maligna - precursor to lentigo maligna melanoma






36. = MEN2a






37. Associated with Wegener granulomatosis






38. Similar to paget breast - sometimes related to underlying adenoCA of sweat glands






39. Aka antiglomerular basement membrane dx - antibodies against alveolar and glomerular basement membranes - linear immunoflorescence






40. Tumor suppressor mutated in Von Recklinhousen






41. Seen in CLL - leukemic B- cells that are fragile






42. Gene product facilitates apoptosis






43. Aka hereditary hemorrhagic telangectasia - telangectasias in skin and mucous membranes - epistaxis - GI bleeds






44. Chromosome 19 - allele common in alzheimers






45. Deficient hexosaminidase A - GM2 ganglioside accumulation - especially in neurons - CNS degeneration - mental/motor deterioration - blindness - cherry red spot on macula - death by 4 years of age






46. Gene product inhibits apoptosis






47. Also seen in urine of MM - stacks of RBCs - will have high ESR






48. Aggressive B- cell lymphoma - EBV - starry sky appearance - c myc






49. Peripheral neuropathy - atrophy of muscles - wet - high output cardiac failure - DCM - AV shunting - hypervolemia






50. Deficient glucocerebrosidase - accumulation of glucocerebroside in cells of mononuclear phagocyte system 3 types ::