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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Ring of copper deposited around iris seen in Wilson






2. X linked - absence of plasma cells and serum immunoglobulins - cell mediated immunity still ok - no germinal centers - recurrent bacterial infections - resistances to fungal and viral still - btk gene defect






3. Tumor suppressor common in familial polyposis coli and adenoCA of colon as well as other tumors






4. Hereditary nephritis associated with nerve deafness and ocular disorders - mutation in gene for the a5 chain of type IV collagen






5. Retinoblastoma on chromosome 13






6. Protooncogene mutated in medulary thyroid CA (MENII)






7. Nuclei arranged in horseshoe - shaped pattern about periphery of cell - characteristic of but not specific for granulomatous TB (as opposed to a foreign body giant cell that has scattered nuclei)






8. Aka angiokeratoma corporis diffusum universal - deficient a::galactosidase A - accumulate ceramide trihexoside - skin lesions angiokeratomas - fever - burning pain in extremities - cardiovascular and cerebrovascular involvement - death as adult by re






9. Materal transmission del(15)(q11q13) - aka happy puppet syndrome - mental retardation - ataxia - seizures - inappropriate laughter






10. Malabsorption syndrome - Tropheryma wippelii bacilli - small intestine commonly affected - arthralgias - cardiac - and neuro symptoms






11. Tumor suppressor mutated in Von Recklinhousen






12. Oligohydramnios causes fetus to be smashed






13. Paracentric inversion or translocation with 17 associated with papillary thyroid CA






14. Autosomal recessive - neutropenia - albinism - cranial and peripheral neuropathy - tendency to develop repeated infections - abnormal WBCs (abnormal mictotubul formation and large cytoplasmic granules = lysosomes)






15. Malignant lymphoma with features resembling inflammatory disorder - young men - Reed Sternburg cells






16. B Thalassemia major






17. Seen in CLL - leukemic B- cells that are fragile






18. Seen in hyperacute rejection - = acute inflammation - fibrinoid necrosis of small vessels - and extensive thrombosis






19. Acute promyelocytic leukemia PML gene on 15 and RARa on 17






20. Primary aldosteronism






21. Autoimmune thyroiditis - hyperthyroid - exophthalmos - increased in HLA DR3 and HLA B8 pos people






22. Asbestosis - yellow - brown - rod shaped body with clubbed ends - stain with Prussian blue






23. Aka osteitis deformans - increased osteoclastic and osteoblastic activity






24. Iron deficient anemia associated with upper::esophageal web






25. Aka congenital megacolon - dilation of colon due to absence of ganglion cells






26. Manifestation of lymphplasmocytic lymphoma - B cell neoplasm






27. Osteophytes at PIP joints






28. Aka trisomy 18 - mental retardation - prominent occiput - micrognathia (small jaw) - low::set ears - rocker::bottom feet - finger deformities - congenital heart dx






29. Different in that it is the primary disorder - recurrent vasospasm of small arteries and venules - pallor - cyanosis - fingers and toes - young healthy women






30. Intracytoplasmic inclusions seen in leydig cell tumors p283






31. X linked - aka immunodeficiency with thrombocytopenia and eczema - total immunoglobulins often normal - recurrent infections






32. Impaired tubular reabsorption of tryptophan - pellagra::like manifestations






33. Oncogenes that code for p21 proteins which are membrane signalers






34. Appears as multiple wart - like lesions resembling condyloma accuminatum






35. Occurs in SLE - small vegitations on either or both surfaces of valves






36. Small round blue cell tumor of bone - long bones - kids - 11:22 transloc






37. Aka IgA nephropathy - deposition of IgA in mesangium - benign recurrent hematuria in kids following infection






38. Esophageal diverticulum just above upper esoph sphincter






39. Diffuse nodular diabetic glomerulosclerosis






40. Mutation here causes pseudohypoparathyroidism






41. = MEN2a






42. Hemihypertrophy - macroglossia - organomegaly - neonatal hypoglycemia - various embryonal tumors - deleted WT 2 gene






43. Development of large pituitary adenomas following bilat adrenalectomy






44. Metastatic stomach CA to ovary






45. Similar to Hurler - deficient L iduronosulfate sulfatase - accumulations of heparin sulfate and dermatan sulfate - hepatospenomegaly - micrognathia - retinal degeneration - joint stiffness - mental retardation - cardiac lesions






46. = MEN1






47. Radiologic appearance of periostium in bone tumors






48. Defective cilia - sinusitis - bronchiectasis - situs inversus - sometimes hearing loss and male sterility






49. Tennis racket shaped cytoplasmic inclusion seen in langerhans cells (so also seen in langerhan cell histiocytosis)






50. Philadelphia chromosome - CML bcr abl fusion c - abl on 9 - bcr on 22