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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Paraneoplastic synd looks like myasthenia gravis - often small cell lung CA






2. Non::neoplastic tumor like masses - fibrous replacement of resorbed bone






3. Tumor suppressor mutated in Von Recklinhousen






4. Deficient hexosaminidase A - GM2 ganglioside accumulation - especially in neurons - CNS degeneration - mental/motor deterioration - blindness - cherry red spot on macula - death by 4 years of age






5. Hemihypertrophy - macroglossia - organomegaly - neonatal hypoglycemia - various embryonal tumors - deleted WT 2 gene






6. Vaginal epithelial cell with stippled appearance due to adherent coccobacilli






7. Scheinker syndrome :: prion dx - fatal familial insomnia






8. Aka subcortical leukoencephalopathy - assoc with HTN - multiple lacunar infarcts and progressive demyelination in subcortical area






9. Gene product facilitates apoptosis - decreases bcl::2 and increases Bax






10. = MEN1






11. Appears as multiple wart - like lesions resembling condyloma accuminatum






12. Aka acute disseminated langerhans cell histiocytosis - aggressive - usually fatal - kids hepatosplenomegaly - LAD - pancytopenia - pulmonary involvement - recurrent infections






13. Deficient a1 -4 glucosidase - accumulation of glycogen in liver - heart - skeletal muscle - cardiomegaly - muscle hypotonia - spelnomegaly - intractable hypoglycemia - death from cardiorespiratory failure before age 3






14. Malignant lymphoma with features resembling inflammatory disorder - young men - Reed Sternburg cells






15. Aka superior sulcus tumor - seen in bronchogenic CA - often with Horner's






16. Acute inflammatory demyelinating dx primarily involving peripheral nerves






17. Chromosome 19 - allele common in alzheimers






18. Mutation = paroxysmal nocturnal hemoglobinuria






19. Aka congenital megacolon - dilation of colon due to absence of ganglion cells






20. Seen in papillary thyroid CA






21. Aka pulseless dx - inflammation and stenosis of medium and large sized arteries - often aortic arch thus aortic arch syndrome






22. Protooncogene mutated in medulary thyroid CA (MENII)






23. Autosomal recessive - neutropenia - albinism - cranial and peripheral neuropathy - tendency to develop repeated infections - abnormal WBCs (abnormal mictotubul formation and large cytoplasmic granules = lysosomes)






24. Oligohydramnios causes fetus to be smashed






25. Similar to Hurler - deficient L iduronosulfate sulfatase - accumulations of heparin sulfate and dermatan sulfate - hepatospenomegaly - micrognathia - retinal degeneration - joint stiffness - mental retardation - cardiac lesions






26. Thyroid replacement by fibrous tissue - unkown origin - mimics






27. Seen in granuloma inguinale - multiple organisms filling large histiocytes






28. Aka antiglomerular basement membrane dx - antibodies against alveolar and glomerular basement membranes - linear immunoflorescence






29. Adenomatous polyps with tumors of CNS






30. Superclavicular lymph node identifying metastatic stomach CA






31. Paternal transmission del (15)(q11q13) - hypogonad - hypotonia - mental retardation - behavior probs - uncrontrolled appetite






32. Gene product facilitates apoptosis






33. Ring of copper deposited around iris seen in Wilson






34. Unknown etiology - necrotizing granulomatous vasculitis of small to medium sized vessels of the respiratory tract - kidneys - and other organs - circulating C- ANCAs






35. Deficient debranching enzyme amylo -1 -6- glucosidase - glycogen in liver - heart - skeletal muscle - stunted growth - hepatomegaly - hypoglycemia






36. Hemangioblastoma or cavernous hemangioma of cerebellum - brainstem or retina - adenomas - cysts in liver - kidney - pancreas - and other organs - increased renal cell CA - gene = short arm of chromosome 3






37. Tumor suppressor mutated in breast and ovary






38. Parkinsonism with autonomic dysfunction and orthostatic hypotension






39. Subcutaneous fibrosis of dorsum of penis






40. Aka osteitis deformans - increased osteoclastic and osteoblastic activity






41. Gene mutated in achondroplasia (most common form of dwarfism) - located at 4p16.3






42. DsDNA antibodies and Sm Smith antigen = highly specific for SLE






43. Autosomal recessive - unusually large platelets - lack of 'GPIb IX V'






44. Small round eosinophilic masses found in dieing hepatocytes often containing chromatin remnants seen in viral hepatitis






45. Autosomal recessive - conj hyperbilirubinemia - defect in bili transport - black color to liver






46. Clear cell renal tumor seen in kids






47. Aka pituitary cachexia - generalized panhypopituitarism






48. Esophageal diverticulum just above upper esoph sphincter






49. Different in that it is the primary disorder - recurrent vasospasm of small arteries and venules - pallor - cyanosis - fingers and toes - young healthy women






50. Lots of tumors - breast CA - soft tissue sarc - brain tumors - leukemias - has loss of p53 tumor suppressor gene