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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Binucleated or multinucleated giant cell seen in Hodgkin dx






2. Thrombotic occlusion of major hepatic veins - abnormal pain - jaundice - hepatomegaly - acites - liver failure - assoc with polycythemia vera - hepatocellular CA - and other common neoplasms - may occur as a complication of pregnancy






3. Seen in Down synd - small white spots on periphery of iris






4. Parkinsonism with autonomic dysfunction and orthostatic hypotension






5. Aka thromboangiitis obliterans - acute inflame of small and med arteries of extremities - extending to adjacent veins and nerves - young jewish men - painful ischemic dx - worse with smoking






6. Osteophytes at PIP joints






7. Aka trisomy 18 - mental retardation - prominent occiput - micrognathia (small jaw) - low::set ears - rocker::bottom feet - finger deformities - congenital heart dx






8. Aka pulseless dx - inflammation and stenosis of medium and large sized arteries - often aortic arch thus aortic arch syndrome






9. Deficient hexosaminidase A - GM2 ganglioside accumulation - especially in neurons - CNS degeneration - mental/motor deterioration - blindness - cherry red spot on macula - death by 4 years of age






10. Small round blue cell tumor of bone - long bones - kids - 11:22 transloc






11. Thiamine deficiency - cerebral dysfunction - aka alcoholic encephalopathy - hemorrhagic lesions in the mamillary bodies - confusion - ataxia - ophthalmoplegia - and memory loss plus confabulation p 105 and p115






12. Defective cilia - sinusitis - bronchiectasis - situs inversus - sometimes hearing loss and male sterility






13. Lots of tumors - breast CA - soft tissue sarc - brain tumors - leukemias - has loss of p53 tumor suppressor gene






14. Tumor suppressor mutated in Von Recklinhousen






15. 45 XO - female hypogonadism - hypothyroid - short - webbed neck - 1* amenorrhea p52






16. Tumor suppressor mutated in wilms tumor






17. Retinoblastoma on chromosome 13






18. Autoimmune thyroiditis - hyperthyroid - exophthalmos - increased in HLA DR3 and HLA B8 pos people






19. Autosomal dominant - numerous adenomatous polyps along with osteomas and soft tissue tumors






20. Malabsorption syndrome - Tropheryma wippelii bacilli - small intestine commonly affected - arthralgias - cardiac - and neuro symptoms






21. Combination of hyperthyroidism - nodular goiter - absence of exophthalmos






22. Paraneoplastic synd looks like myasthenia gravis - often small cell lung CA






23. Single erythematous plaque on shaft of penis or scrotum






24. B1 thiamine - B2 riboflavin - B3 niacin - B6 pyridoxine - B12 cobalamin - C ascorbic acid - D calciferol - E a::tocopherol






25. Aka lentigo maligna - precursor to lentigo maligna melanoma






26. Hemihypertrophy - macroglossia - organomegaly - neonatal hypoglycemia - various embryonal tumors - deleted WT 2 gene






27. Development of large pituitary adenomas following bilat adrenalectomy






28. Deficient sphingomyelinase - accumulation of sphingomyelin in phagocytes - foamy histiocytes in liver - spleen - lymph nodes - skin - hepatosplenomegaly - anemia fever - occasional neuro degeneration - half have cherry red spot macula






29. Myc :: neuroblastoma amplicatiion correlates inversely with degree of differentiation






30. Malignant lymphoma with features resembling inflammatory disorder - young men - Reed Sternburg cells






31. Vasosmasm of small vessels - most often in fingers - seen with autoimmune dx like SLE - scleroderma and others (R in CREST) - recurrent vasospasm - always secondary to underlying disorder






32. Nystagmus - intention tremor - scanning speech - seen in MS






33. Acute promyelocytic leukemia PML gene on 15 and RARa on 17






34. B Thalassemia major






35. Urethritis - conjunctivitis - arthritis - associated with venereal or intestinal infection






36. Downward displacement of cerebellar tonsils and medulla through foramen magnum






37. Primary adrenal failure






38. Pituitary insufficiency post - partum - low TSH ACTH






39. Iron deficient anemia associated with upper::esophageal web






40. Variant of rheumatoid arthritis - aka juvenile rheumatoid arthritis






41. Aka congenital megacolon - dilation of colon due to absence of ganglion cells






42. Superclavicular lymph node identifying metastatic stomach CA






43. Manifestation of lymphplasmocytic lymphoma - B cell neoplasm






44. Subcutaneous fibrosis of dorsum of penis






45. Tumor suppressor common in familial polyposis coli and adenoCA of colon as well as other tumors






46. Autoimmune hypothyroid - hurthle cells common






47. Also seen in urine of MM - stacks of RBCs - will have high ESR






48. Aka pituitary cachexia - generalized panhypopituitarism






49. Scheinker syndrome :: prion dx - fatal familial insomnia






50. Aka subcortical leukoencephalopathy - assoc with HTN - multiple lacunar infarcts and progressive demyelination in subcortical area