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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Aka thromboangiitis obliterans - acute inflame of small and med arteries of extremities - extending to adjacent veins and nerves - young jewish men - painful ischemic dx - worse with smoking






2. Hemihypertrophy - macroglossia - organomegaly - neonatal hypoglycemia - various embryonal tumors - deleted WT 2 gene






3. Intra::alveolar hemosiderin - laden macrophages caused by RBCs from capillary rupture 2* to pulmonary HTN






4. Ovarian tumor resembling bladder transitional epith






5. Aka chronic progressive histiocytosis - not as bad as Letterer Siwe






6. Small round blue cell tumor of bone - long bones - kids - 11:22 transloc






7. Deficient muscle phosphorylase - glycogen in skeletal muscle - cramps with exertion






8. Catastrophic adrenal insuff and vascular collapse - hemorrhagic necrosis of adrenal cortex






9. Appears as multiple wart - like lesions resembling condyloma accuminatum






10. Intracytoplasmic inclusions seen in leydig cell tumors p283






11. Pigmented iris hamartoma seen in neurofibromatosis






12. 2/neu :: oncogene (aka c - erbB2) - in breast cancer = poor prognosis






13. Aka velocardiofacial syndrome and CATCH 22 syndrome - micro deletion of 22q11 - Cardiac abnormalities - Abnormal facies - T cell deficit due to thymic hypoplasia - Cleft palate - Hypocalcemia due to hypoparathyroidism - from poor development of 3rd a






14. Mutation = paroxysmal nocturnal hemoglobinuria






15. Hamartomatous polyps in colon and small intest - freckles on lips - hands - genitalia - higher incidence of adeno CA of colon and other malignancies - stomach - breast - ovaries






16. Similar to Hurler - deficient L iduronosulfate sulfatase - accumulations of heparin sulfate and dermatan sulfate - hepatospenomegaly - micrognathia - retinal degeneration - joint stiffness - mental retardation - cardiac lesions






17. Tumor suppressor mutated in Von Recklinhousen






18. Mucopolysaccharidosis - deficient a L iduronidase - accumulations of heparin sulfate and dermatan sulfate in heart - brain - liver - and other organs - progressive - hepatosplenomagaly - dwarfism - gargoyle - like facies - stubby fingers - corneal cl






19. X linked - aka immunodeficiency with thrombocytopenia and eczema - total immunoglobulins often normal - recurrent infections






20. Binucleated or multinucleated giant cell seen in Hodgkin dx






21. Metastatic stomach CA to ovary






22. Gene product facilitates apoptosis






23. Similar to Dubin Johnson with no black liver






24. On lymph node biopsy - seen with Burkitt lymphoma






25. Acute inflammatory demyelinating dx primarily involving peripheral nerves






26. Eosinophilic intracytoplasmic inclusions in hippocampus and purkinje cells seen in rabies infection






27. Epithelial cells with eosinophilc granular cytoplasm seen in hashimoto






28. Hemangioblastoma or cavernous hemangioma of cerebellum - brainstem or retina - adenomas - cysts in liver - kidney - pancreas - and other organs - increased renal cell CA - gene = short arm of chromosome 3






29. Hereditary nonpolyposis colon cancer - DNA repair genes messed up






30. Aka polycystic ovary syndrome - young women - amenorrhea - infertility - obesity - hirsutism






31. Seen in papillary thyroid CA






32. 45 XO - female hypogonadism - hypothyroid - short - webbed neck - 1* amenorrhea p52






33. Philadelphia chromosome - CML bcr abl fusion c - abl on 9 - bcr on 22






34. Primary adrenal failure






35. Autoimmune thyroiditis - hyperthyroid - exophthalmos - increased in HLA DR3 and HLA B8 pos people






36. Oligohydramnios causes fetus to be smashed






37. Deficient sphingomyelinase - accumulation of sphingomyelin in phagocytes - foamy histiocytes in liver - spleen - lymph nodes - skin - hepatosplenomegaly - anemia fever - occasional neuro degeneration - half have cherry red spot macula






38. X linked - absence of plasma cells and serum immunoglobulins - cell mediated immunity still ok - no germinal centers - recurrent bacterial infections - resistances to fungal and viral still - btk gene defect






39. B1 thiamine - B2 riboflavin - B3 niacin - B6 pyridoxine - B12 cobalamin - C ascorbic acid - D calciferol - E a::tocopherol






40. Impaired tubular reabsorption of tryptophan - pellagra::like manifestations






41. Downward displacement of cerebellar tonsils and medulla through foramen magnum






42. Subcutaneous fibrosis of dorsum of penis






43. Associated with breast alone (isn't one of these associated with prostate? Check)






44. Thrombotic occlusion of major hepatic veins - abnormal pain - jaundice - hepatomegaly - acites - liver failure - assoc with polycythemia vera - hepatocellular CA - and other common neoplasms - may occur as a complication of pregnancy






45. Myc :: neuroblastoma amplicatiion correlates inversely with degree of differentiation






46. Esophageal diverticulum just above upper esoph sphincter






47. Similar to paget breast - sometimes related to underlying adenoCA of sweat glands






48. Protooncogene mutated in medulary thyroid CA (MENII)






49. Aka angiokeratoma corporis diffusum universal - deficient a::galactosidase A - accumulate ceramide trihexoside - skin lesions angiokeratomas - fever - burning pain in extremities - cardiovascular and cerebrovascular involvement - death as adult by re






50. Severe unconj hyperbilirubinemia due to deficient glucuronyl transferase