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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Aka pulseless dx - inflammation and stenosis of medium and large sized arteries - often aortic arch thus aortic arch syndrome






2. Also seen in urine of MM - stacks of RBCs - will have high ESR






3. Aka osteopetrosis - marble bone dx - dense skeleton - failure of osteoclastic activity






4. Autosomal recessive - conj hyperbilirubinemia - defect in bili transport - black color to liver






5. Small follicles filled with eosinophilic secretion - diagnostic feature of granulose cell tumor






6. Seen in hyperacute rejection - = acute inflammation - fibrinoid necrosis of small vessels - and extensive thrombosis






7. Parkinsonism with autonomic dysfunction and orthostatic hypotension






8. Hereditary nonpolyposis colon cancer - DNA repair genes messed up






9. Hereditary nephritis associated with nerve deafness and ocular disorders - mutation in gene for the a5 chain of type IV collagen






10. Lots of tumors - breast CA - soft tissue sarc - brain tumors - leukemias - has loss of p53 tumor suppressor gene






11. Similar to Dubin Johnson with no black liver






12. Seen in papillary thyroid CA






13. Autosomal dominant - fatal - progressive degeneration of striatum and frontal cortex with neuronal depletion and gliosis






14. Triad of ovarian fibroma - ascites - hydrothorax






15. Small round eosinophilic masses found in dieing hepatocytes often containing chromatin remnants seen in viral hepatitis






16. Paraneoplastic synd looks like myasthenia gravis - often small cell lung CA






17. Thiamine deficiency - cerebral dysfunction - aka alcoholic encephalopathy - hemorrhagic lesions in the mamillary bodies - confusion - ataxia - ophthalmoplegia - and memory loss plus confabulation p 105 and p115






18. Single erythematous plaque on shaft of penis or scrotum






19. Intracytoplasmic proximal dentritic eosinophilic inclusions consisting of actin seen in Alzheimers






20. Tumor suppressor mutated in wilms tumor






21. Deficient a1 -4 glucosidase - accumulation of glycogen in liver - heart - skeletal muscle - cardiomegaly - muscle hypotonia - spelnomegaly - intractable hypoglycemia - death from cardiorespiratory failure before age 3






22. Downward displacement of cerebellar tonsils and medulla through foramen magnum






23. Clear cell renal tumor seen in kids






24. X linked - absence of plasma cells and serum immunoglobulins - cell mediated immunity still ok - no germinal centers - recurrent bacterial infections - resistances to fungal and viral still - btk gene defect






25. Aka osteitis deformans - increased osteoclastic and osteoblastic activity






26. Pituitary insufficiency post - partum - low TSH ACTH






27. Occurs in SLE - small vegitations on either or both surfaces of valves






28. Nuclei arranged in horseshoe - shaped pattern about periphery of cell - characteristic of but not specific for granulomatous TB (as opposed to a foreign body giant cell that has scattered nuclei)






29. Oncogenes that code for p21 proteins which are membrane signalers






30. Osteophytes at DIP joints






31. Aka antiglomerular basement membrane dx - antibodies against alveolar and glomerular basement membranes - linear immunoflorescence






32. Hemangioblastoma or cavernous hemangioma of cerebellum - brainstem or retina - adenomas - cysts in liver - kidney - pancreas - and other organs - increased renal cell CA - gene = short arm of chromosome 3






33. Tennis racket shaped cytoplasmic inclusion seen in langerhans cells (so also seen in langerhan cell histiocytosis)






34. Aka pituitary cachexia - generalized panhypopituitarism






35. Mucopolysaccharidosis - deficient a L iduronidase - accumulations of heparin sulfate and dermatan sulfate in heart - brain - liver - and other organs - progressive - hepatosplenomagaly - dwarfism - gargoyle - like facies - stubby fingers - corneal cl






36. Associated with 90% cases of ankylosing spondylitis - common in rheumatoid arthritis






37. DsDNA antibodies and Sm Smith antigen = highly specific for SLE






38. Gene product inhibits apoptosis






39. Intracytoplasmic inclusions seen in leydig cell tumors p283






40. Mesangial matrix material acculmulations seen in nodular glomerulosclerosis seen in diabetic nephropathy






41. Hemihypertrophy - macroglossia - organomegaly - neonatal hypoglycemia - various embryonal tumors - deleted WT 2 gene






42. Variant of rheumatoid arthritis - splenmegally - neutropenia - RA






43. Tumor suppressor mutated in Von Recklinhousen






44. Manifestation of lymphplasmocytic lymphoma - B cell neoplasm






45. Burkitts c::myc is on 8 - IG heavy chain is on 14






46. Infectious disorder - caused postencephalitic parkinsonism






47. Aka congenital megacolon - dilation of colon due to absence of ganglion cells






48. Osteophytes at PIP joints






49. Seen in Down synd - small white spots on periphery of iris






50. Modest elevated serum unconj bilirubin - due to decreased uptake by liver cells and reduced activity of glucuronyl transferase







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