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Test your basic knowledge |
USMLE Brs Pathology Vocab
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Subjects
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health-sciences
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usmle
Instructions:
Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Acute promyelocytic leukemia PML gene on 15 and RARa on 17
Denys Drash syndrome
15:17
Rb gene
Turcot syndrome
2. Hamartomatous polyps in colon and small intest - freckles on lips - hands - genitalia - higher incidence of adeno CA of colon and other malignancies - stomach - breast - ovaries
Peutz Jeghers syndrome
Von Recklinhousen dx
Hodgkin dx
Clue cell
3. Mutation here causes pseudohypoparathyroidism
Takayasu arteritis
Hashimoto thyroiditis
Waldenstrom Macroglobulinemia
GNAS1
4. Defective in x- linked brutons agammaglobulinemia - B- cell tyrosine kinase
Fanconi syndrome
Felty syndrome
Peutz Jeghers syndrome
Btk gene
5. Small round eosinophilic masses found in dieing hepatocytes often containing chromatin remnants seen in viral hepatitis
Hodgkin dx
Councilman body
Orphan annie nuclei
Beriberi
6. X linked - absence of plasma cells and serum immunoglobulins - cell mediated immunity still ok - no germinal centers - recurrent bacterial infections - resistances to fungal and viral still - btk gene defect
Brutons Agammaglobulinemia
Bax
Foamy histiocyte
Krukenberg tumor
7. Deficient fibrillin (constituent of microfibrils) - arachnodactyly - ectopia lentis - aortic aneurysm - mitral valve prolapsed
Marfan syndrome
Reidel thyroiditis
Stein Leventhal syndrome
Kartagener syndrome
8. Vasosmasm of small vessels - most often in fingers - seen with autoimmune dx like SLE - scleroderma and others (R in CREST) - recurrent vasospasm - always secondary to underlying disorder
Conn syndrome
Raynaud phenomenon
Cri du chat syndrome
Orphan annie nuclei
9. Aka osteopetrosis - marble bone dx - dense skeleton - failure of osteoclastic activity
Raynaud disease
Denys Drash syndrome
Meigs syndrome
Albers SCHonberg dx
10. Deficient debranching enzyme amylo -1 -6- glucosidase - glycogen in liver - heart - skeletal muscle - stunted growth - hepatomegaly - hypoglycemia
Cori dx
Von economo encephalitis
Pancoast tumor
BRCA1
11. B Thalassemia major
Reed Sternburg cell
Osler Weber Rendu syndrome
Mediterranean anemia or Cooley Anemia
Virchow node
12. Aneurysm at small artery bifurcations
Arthus reaction
Takayasu arteritis
Prader willi syndrome
Charcot Bouchard aneurysm
13. Gene product facilitates apoptosis
Brenner tumor
Bax
Marfan syndrome
Von Recklinhousen dx
14. Scheinker syndrome :: prion dx - fatal familial insomnia
Councilman body
8:14
Raynaud disease
Gerstmann Straussler
15. Triad of ovarian fibroma - ascites - hydrothorax
Meigs syndrome
Cori dx
Heart failure cells
Hurthle cell
16. This comes in a wet variety and a dry one - they are both Vit B1 thiamine deficiency
Beriberi
Whipple dx
Arthus reaction
Fabry dx
17. Located on xsome 6 - mutation here = hereditary hemochromatosis
Fanconi syndrome
Arthus reaction
Gardner syndrome
Hfe gene
18. Superclavicular lymph node identifying metastatic stomach CA
Chromosome 10
Sipple syndrome
Bcl2
Virchow node
19. Aka acute disseminated langerhans cell histiocytosis - aggressive - usually fatal - kids hepatosplenomegaly - LAD - pancytopenia - pulmonary involvement - recurrent infections
Letterer Siwe dx
Hurler syndrome
C ANCA
Li Fraumeni syndrome
20. Infectious disorder - caused postencephalitic parkinsonism
Von economo encephalitis
Brenner tumor
Lesch Nyhan syndrome
Edwards syndrome
21. Aggressive B- cell lymphoma - EBV - starry sky appearance - c myc
Paget dx of bone
BRCA1
Heart failure cells
Burkitt lymphoma
22. Intra::alveolar hemosiderin - laden macrophages caused by RBCs from capillary rupture 2* to pulmonary HTN
Fanconi syndrome
Hunter syndrome
Starry sky appearance
Heart failure cells
23. Autosomal dominant - numerous adenomatous polyps along with osteomas and soft tissue tumors
Buerger dx
Gardner syndrome
Negri bodies
HER
24. Deficient hypoxanthine::guanine phosphoribosyltransferase (HGPRT) - low purine metabolism - high uric acid - thus gout - mental retardation - choreoathetosis - spasticity - self mutilation - aggressiveness
Birbeck granule
Lesch Nyhan syndrome
ret
Marfan syndrome
25. Iron deficient anemia associated with upper::esophageal web
Call Exner bodies
Plummer Vinson syndrome
Hurler syndrome
Wermer syndrome
26. Metastatic stomach CA to ovary
Hfe gene
Krukenberg tumor
Li Fraumeni syndrome
Von Recklinhousen dx
27. Seen in hyperacute rejection - = acute inflammation - fibrinoid necrosis of small vessels - and extensive thrombosis
HLA B27 antigen
Patau syndrome
Heart failure cells
Arthus reaction
28. = MEN1
Bowen dx
Hand Schuller Christian dx
Wermer syndrome
Cri du chat syndrome
29. Modest elevated serum unconj bilirubin - due to decreased uptake by liver cells and reduced activity of glucuronyl transferase
Wernicke Korsakoff syndrome
Gilbert syndrome
Reidel thyroiditis
Letterer Siwe dx
30. DsDNA antibodies and Sm Smith antigen = highly specific for SLE
ANAs in SLE
Aschoff body
Dry beriberi
Brutons Agammaglobulinemia
31. Tumor suppressor common in familial polyposis coli and adenoCA of colon as well as other tumors
ret PTC
Pancoast tumor
APC
McCune Albright syndrome
32. Aka thromboangiitis obliterans - acute inflame of small and med arteries of extremities - extending to adjacent veins and nerves - young jewish men - painful ischemic dx - worse with smoking
Buerger dx
15:17
Sturge Weber syndrome
Koilocyte
33. Aka trisomy 13 - mental retardation - microcephaly - micropthalmia - brain abnormalities - cleft lip/palate - polydactyly - rockerbottom feet - congenital heart dx
Ferruginous body
Hashimoto thyroiditis
Hfe gene
Patau syndrome
34. Seen in Down synd - small white spots on periphery of iris
Von economo encephalitis
Addison disease
Hartnup dx
Brushfield spots
35. Aka antiglomerular basement membrane dx - antibodies against alveolar and glomerular basement membranes - linear immunoflorescence
Dry beriberi
Prader willi syndrome
Goodpasture syndrome
Niemann Pick dx
36. Aka polycystic ovary syndrome - young women - amenorrhea - infertility - obesity - hirsutism
Langhans giant cell
Waldenstrom Macroglobulinemia
Stein Leventhal syndrome
Wilms tumor
37. Deficient muscle phosphorylase - glycogen in skeletal muscle - cramps with exertion
Brushfield spots
Call Exner bodies
McArdle syndrome
Lynch syndrome
38. Hereditary nonpolyposis colon cancer - DNA repair genes messed up
Lynch syndrome
Crigler Najjar syndrome
Hurler syndrome
Kawasaki dx
39. Nystagmus - intention tremor - scanning speech - seen in MS
Charcot triad
Hirschsprung dx
Shy Drager syndrome
9:22
40. Autosomal dominant - fatal - progressive degeneration of striatum and frontal cortex with neuronal depletion and gliosis
Huntington dx
Cori dx
C ANCA
Smudge cells
41. Unknown etiology - necrotizing granulomatous vasculitis of small to medium sized vessels of the respiratory tract - kidneys - and other organs - circulating C- ANCAs
Stein Leventhal syndrome
Chromosome 10
Wegener granulomatosis
Peutz Jeghers syndrome
42. Appears as multiple wart - like lesions resembling condyloma accuminatum
Bowenoid papulosis
Paget dx of breast
PIG A
Paget dx of bone
43. Osteophytes at DIP joints
Buerger dx
Heberden nodes
Kawasaki dx
Reye syndrome
44. Impaired tubular reabsorption of tryptophan - pellagra::like manifestations
McArdle syndrome
Chediak Higashi syndrome
N
Hartnup dx
45. Hemangioblastoma or cavernous hemangioma of cerebellum - brainstem or retina - adenomas - cysts in liver - kidney - pancreas - and other organs - increased renal cell CA - gene = short arm of chromosome 3
Still disease
Patau syndrome
Von Hippel Lindau dx
Edwards syndrome
46. Aka osteitis deformans - increased osteoclastic and osteoblastic activity
Lesch Nyhan syndrome
Goodpasture syndrome
Virchow node
Paget dx of bone
47. Gene product facilitates apoptosis - decreases bcl::2 and increases Bax
Ras oncogenes
Buerger dx
Pompe dx
p53
48. Aka allergic granulomatous angiitis - necrotizing vasculitis - variant of polyarteritis nodosa - involves pulmonary vasculature - peripheral eosinophilia - and asthma
Brenner tumor
Von economo encephalitis
Churg Strauss syndrome
Kayser Fleischer ring
49. Deficient glucocerebrosidase - accumulation of glucocerebroside in cells of mononuclear phagocyte system 3 types ::
Gaucher dx
Bernard Soulier dx
Klinefelter syndrome
Smudge cells
50. Autoimmune hypothyroid - hurthle cells common
Hand Schuller Christian dx
Beckwith Weidemann syndrome
Fabry dx
Hashimoto thyroiditis
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