Test your basic knowledge |

USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Aka polycystic ovary syndrome - young women - amenorrhea - infertility - obesity - hirsutism






2. Downward displacement of cerebellar tonsils and medulla through foramen magnum






3. Seen in hyperacute rejection - = acute inflammation - fibrinoid necrosis of small vessels - and extensive thrombosis






4. Modest elevated serum unconj bilirubin - due to decreased uptake by liver cells and reduced activity of glucuronyl transferase






5. Sphingomyelin containing phagocytes seen in Niemman::Pick dx in liver - spleen - lymph nodes and skin






6. Aka velocardiofacial syndrome and CATCH 22 syndrome - micro deletion of 22q11 - Cardiac abnormalities - Abnormal facies - T cell deficit due to thymic hypoplasia - Cleft palate - Hypocalcemia due to hypoparathyroidism - from poor development of 3rd a






7. Retinoblastoma on chromosome 13






8. Mucinous cell - characteristic of stomach CA met to ovary (krukenberg tumor)






9. Philadelphia chromosome - CML bcr abl fusion c - abl on 9 - bcr on 22






10. = MEN1






11. Pituitary insufficiency post - partum - low TSH ACTH






12. Tumor suppressor mutated in Von Recklinhousen






13. Thyroid replacement by fibrous tissue - unkown origin - mimics






14. Osteophytes at DIP joints






15. Iron deficient anemia associated with upper::esophageal web






16. Appears as multiple wart - like lesions resembling condyloma accuminatum






17. Area of focal interstitial myocardial inflammation characterized by fragmented collagen and fibrinoid material - by large cells (Anitschkow myocytes) and occasional multinucleated giant cells (Aschoff cells)






18. Ring of copper deposited around iris seen in Wilson






19. Metastatic stomach CA to ovary






20. Unknown etiology - necrotizing granulomatous vasculitis of small to medium sized vessels of the respiratory tract - kidneys - and other organs - circulating C- ANCAs






21. Mutation here causes pseudohypoparathyroidism






22. Deficient a1 -4 glucosidase - accumulation of glycogen in liver - heart - skeletal muscle - cardiomegaly - muscle hypotonia - spelnomegaly - intractable hypoglycemia - death from cardiorespiratory failure before age 3






23. Deficient glucose -6- phosphatase - accumulation of glycogen in liver and kidney - hepatomegaly - hypoglycemia






24. Similar to paget breast - sometimes related to underlying adenoCA of sweat glands






25. Deficient hexosaminidase A - GM2 ganglioside accumulation - especially in neurons - CNS degeneration - mental/motor deterioration - blindness - cherry red spot on macula - death by 4 years of age






26. Seen in CLL - leukemic B- cells that are fragile






27. Adenomatous polyps with tumors of CNS






28. Seen in Down synd - small white spots on periphery of iris






29. Manifestation of lymphplasmocytic lymphoma - B cell neoplasm






30. Osteophytes at PIP joints






31. Acute inflammatory demyelinating dx primarily involving peripheral nerves






32. Hemorrhagic urticaria of extensor surgaces of arms - legs - and buttocks - with fever - arthralgias - and GI renal involvement similar to IgA nephropathy - associated with URIs






33. Tumor suppressor mutated in wilms tumor






34. Variant of rheumatoid arthritis - splenmegally - neutropenia - RA






35. Small follicles filled with eosinophilic secretion - diagnostic feature of granulose cell tumor






36. Superclavicular lymph node identifying metastatic stomach CA






37. Deficient debranching enzyme amylo -1 -6- glucosidase - glycogen in liver - heart - skeletal muscle - stunted growth - hepatomegaly - hypoglycemia






38. Seen in insulinoma - episodic hyperinsulinemia and hypoglycemia - CNS dysfunction - reversal of CNS probs with administration of glucose






39. Intracytoplasmic proximal dentritic eosinophilic inclusions consisting of actin seen in Alzheimers






40. Gene product facilitates apoptosis






41. Triad of ovarian fibroma - ascites - hydrothorax






42. 45 XO - female hypogonadism - hypothyroid - short - webbed neck - 1* amenorrhea p52






43. Tennis racket shaped cytoplasmic inclusion seen in langerhans cells (so also seen in langerhan cell histiocytosis)






44. Thiamine deficiency - cerebral dysfunction - aka alcoholic encephalopathy - hemorrhagic lesions in the mamillary bodies - confusion - ataxia - ophthalmoplegia - and memory loss plus confabulation p 105 and p115






45. X linked - aka immunodeficiency with thrombocytopenia and eczema - total immunoglobulins often normal - recurrent infections






46. Associated with papillary thyroid CA






47. Seen in granuloma inguinale - multiple organisms filling large histiocytes






48. Lots of tumors - breast CA - soft tissue sarc - brain tumors - leukemias - has loss of p53 tumor suppressor gene






49. Combination of hyperthyroidism - nodular goiter - absence of exophthalmos






50. Autosomal recessive - conj hyperbilirubinemia - defect in bili transport - black color to liver