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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Nuclei arranged in horseshoe - shaped pattern about periphery of cell - characteristic of but not specific for granulomatous TB (as opposed to a foreign body giant cell that has scattered nuclei)






2. Adenomatous polyps with tumors of CNS






3. Gene product facilitates apoptosis






4. Small follicles filled with eosinophilic secretion - diagnostic feature of granulose cell tumor






5. Deficient fibrillin (constituent of microfibrils) - arachnodactyly - ectopia lentis - aortic aneurysm - mitral valve prolapsed






6. Nystagmus - intention tremor - scanning speech - seen in MS






7. Aka lentigo maligna - precursor to lentigo maligna melanoma






8. Triad of ovarian fibroma - ascites - hydrothorax






9. Downward displacement of cerebellar tonsils and medulla through foramen magnum






10. Philadelphia chromosome - CML bcr abl fusion c - abl on 9 - bcr on 22






11. Subcutaneous fibrosis of dorsum of penis






12. Seen in papillary thyroid CA






13. Aggressive B- cell lymphoma - EBV - starry sky appearance - c myc






14. Autoimmune thyroiditis - hyperthyroid - exophthalmos - increased in HLA DR3 and HLA B8 pos people






15. Aka trisomy 13 - mental retardation - microcephaly - micropthalmia - brain abnormalities - cleft lip/palate - polydactyly - rockerbottom feet - congenital heart dx






16. Minute neutrophilic abscesses found within parakeratotic stratum corneum in psoriasis






17. Mucopolysaccharidosis - deficient a L iduronidase - accumulations of heparin sulfate and dermatan sulfate in heart - brain - liver - and other organs - progressive - hepatosplenomagaly - dwarfism - gargoyle - like facies - stubby fingers - corneal cl






18. Small round eosinophilic masses found in dieing hepatocytes often containing chromatin remnants seen in viral hepatitis






19. Chromosome 19 - allele common in alzheimers






20. Impaired tubular reabsorption of tryptophan - pellagra::like manifestations






21. Malabsorption syndrome - Tropheryma wippelii bacilli - small intestine commonly affected - arthralgias - cardiac - and neuro symptoms






22. Gene product facilitates apoptosis - decreases bcl::2 and increases Bax






23. Deficient a1 -4 glucosidase - accumulation of glycogen in liver - heart - skeletal muscle - cardiomegaly - muscle hypotonia - spelnomegaly - intractable hypoglycemia - death from cardiorespiratory failure before age 3






24. Osteophytes at PIP joints






25. Seen in hyperacute rejection - = acute inflammation - fibrinoid necrosis of small vessels - and extensive thrombosis






26. Paracentric inversion or translocation with 17 associated with papillary thyroid CA






27. Catastrophic adrenal insuff and vascular collapse - hemorrhagic necrosis of adrenal cortex






28. Appears as multiple wart - like lesions resembling condyloma accuminatum






29. Pigmented iris hamartoma seen in neurofibromatosis






30. Aka infantile progressive spinal muscular atrophy - autosomal recessive - LMN disease - infants






31. Gene mutated in achondroplasia (most common form of dwarfism) - located at 4p16.3






32. Eosinophilic intracytoplasmic inclusions in hippocampus and purkinje cells seen in rabies infection






33. Dysplastic cell seen in HPV






34. Aka antiglomerular basement membrane dx - antibodies against alveolar and glomerular basement membranes - linear immunoflorescence






35. Occurs in SLE - small vegitations on either or both surfaces of valves






36. Aka chronic progressive histiocytosis - not as bad as Letterer Siwe






37. X linked - aka immunodeficiency with thrombocytopenia and eczema - total immunoglobulins often normal - recurrent infections






38. Hereditary nonpolyposis colon cancer - DNA repair genes messed up






39. Autosomal recessive - conj hyperbilirubinemia - defect in bili transport - black color to liver






40. Vasosmasm of small vessels - most often in fingers - seen with autoimmune dx like SLE - scleroderma and others (R in CREST) - recurrent vasospasm - always secondary to underlying disorder






41. Esophageal diverticulum just above upper esoph sphincter






42. Intracytoplasmic inclusions seen in leydig cell tumors p283






43. Seen in insulinoma - episodic hyperinsulinemia and hypoglycemia - CNS dysfunction - reversal of CNS probs with administration of glucose






44. Tumor suppressor common in familial polyposis coli and adenoCA of colon as well as other tumors






45. Polyostotic fibrous dysplasia - precocious puberty - caf






46. Aka pituitary cachexia - generalized panhypopituitarism






47. 2/neu :: oncogene (aka c - erbB2) - in breast cancer = poor prognosis






48. X linked - absence of plasma cells and serum immunoglobulins - cell mediated immunity still ok - no germinal centers - recurrent bacterial infections - resistances to fungal and viral still - btk gene defect






49. Paraneoplastic synd looks like myasthenia gravis - often small cell lung CA






50. 5p chromosome deletion - severe mental retardation - microcephaly - catlike cry - low birth weight - round face - hypertelorism (wide eyes)