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Test your basic knowledge |
USMLE Brs Pathology Vocab
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Study First
Subjects
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health-sciences
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usmle
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
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Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Oncogenes that code for p21 proteins which are membrane signalers
Berger dx
Ras oncogenes
Wilms tumor
Shy Drager syndrome
2. Abnormal WT 1 gene - intersexual disorders - nephropathy - wilms tumor
Cori dx
Brutons Agammaglobulinemia
Zenker diverticulum
Denys Drash syndrome
3. Autosomal dominant - fatal - progressive degeneration of striatum and frontal cortex with neuronal depletion and gliosis
Huntington dx
APC
Reye syndrome
Kimmelsteil Wilson dx
4. Intra::alveolar hemosiderin - laden macrophages caused by RBCs from capillary rupture 2* to pulmonary HTN
BRCA2
Heart failure cells
Alport syndrome
Krukenberg tumor
5. Malabsorption syndrome - Tropheryma wippelii bacilli - small intestine commonly affected - arthralgias - cardiac - and neuro symptoms
Whipple dx
Wegener granulomatosis
Paget dx of vulva
Burkitt lymphoma
6. Paracentric inversion or translocation with 17 associated with papillary thyroid CA
Chromosome 10
Alport syndrome
Virchow node
Denys Drash syndrome
7. Superclavicular lymph node identifying metastatic stomach CA
Li Fraumeni syndrome
Virchow node
Albers SCHonberg dx
Buerger dx
8. Aka trisomy 18 - mental retardation - prominent occiput - micrognathia (small jaw) - low::set ears - rocker::bottom feet - finger deformities - congenital heart dx
Guillain Barre syndrome
Gardner syndrome
Kawasaki dx
Edwards syndrome
9. Scheinker syndrome :: prion dx - fatal familial insomnia
Pompe dx
Gerstmann Straussler
Kimmelstiel Wilson nodules
Lambert Eaton syndrome
10. Sphingomyelin containing phagocytes seen in Niemman::Pick dx in liver - spleen - lymph nodes and skin
Binswanger dx
Turcot syndrome
Foamy histiocyte
p53
11. Aspirin toxicity seen in kids after acute febrile viral dx - microvesicular fatty change in liver and encephalopathy
Hashimoto thyroiditis
GNAS1
Reye syndrome
Churg Strauss syndrome
12. Associated with Wegener granulomatosis
Binswanger dx
C ANCA
Ras oncogenes
Raynaud phenomenon
13. Aka lentigo maligna - precursor to lentigo maligna melanoma
Still disease
Hutchinson freckle
Wegener granulomatosis
Hodgkin dx
14. Seen in hyperacute rejection - = acute inflammation - fibrinoid necrosis of small vessels - and extensive thrombosis
Arthus reaction
11:22
Hurler syndrome
Signet ring cell
15. Osteophytes at PIP joints
Heberden nodes
Paget dx of breast
Bouchard nodes
Langhans giant cell
16. Transloc seen in ewing sarcoma
11:22
Smudge cells
Libman Sacks endocarditis
Hashimoto thyroiditis
17. Eosinophilic intracytoplasmic inclusions in hippocampus and purkinje cells seen in rabies infection
Aschoff body
Alport syndrome
McCune Albright syndrome
Negri bodies
18. X linked - aka immunodeficiency with thrombocytopenia and eczema - total immunoglobulins often normal - recurrent infections
Klinefelter syndrome
Von Gierke dx
Wiskott Aldrich syndrome
Munro abscesses
19. Primary aldosteronism
Wilson dx
Felty syndrome
Klinefelter syndrome
Conn syndrome
20. Osteophytes at DIP joints
Wilson dx
Rouleaux formation
Rb gene
Heberden nodes
21. Defective in x- linked brutons agammaglobulinemia - B- cell tyrosine kinase
Kimmelsteil Wilson dx
Btk gene
Hirschsprung dx
Bax
22. Vaginal epithelial cell with stippled appearance due to adherent coccobacilli
Clue cell
Werdnig Hoffman syndrome
Berger dx
Raynaud disease
23. Metastatic stomach CA to ovary
Simmonds dx
Whipple dx
Wilson dx
Krukenberg tumor
24. Severe unconj hyperbilirubinemia due to deficient glucuronyl transferase
NF1
Crigler Najjar syndrome
BRCA2
Klinefelter syndrome
25. Aka acute disseminated langerhans cell histiocytosis - aggressive - usually fatal - kids hepatosplenomegaly - LAD - pancytopenia - pulmonary involvement - recurrent infections
Dubin Johnson syndrome
Von Hippel Lindau dx
FGFR3
Letterer Siwe dx
26. Deficient glucocerebrosidase - accumulation of glucocerebroside in cells of mononuclear phagocyte system 3 types ::
Gaucher dx
Niemann Pick dx
11:22
Henoch Schonlein Purpura
27. Aka polycystic ovary syndrome - young women - amenorrhea - infertility - obesity - hirsutism
Von Recklinhousen dx
BRCA1
Lynch syndrome
Stein Leventhal syndrome
28. Intracytoplasmic inclusions seen in leydig cell tumors p283
Sipple syndrome
Reinke crystal
15:17
Foamy histiocyte
29. 5p chromosome deletion - severe mental retardation - microcephaly - catlike cry - low birth weight - round face - hypertelorism (wide eyes)
Albers SCHonberg dx
Cri du chat syndrome
Clue cell
Patau syndrome
30. Autosomal recessive - unusually large platelets - lack of 'GPIb IX V'
Clue cell
Bernard Soulier dx
HER
Beriberi
31. Seen in CLL - leukemic B- cells that are fragile
Aschoff body
Rouleaux formation
Negri bodies
Smudge cells
32. Eczematoid lesion of nipple areola - large cells with clear 'halo like' area - invade epidermis - underlying ductal CA
Paget dx of breast
Kartagener syndrome
BRCA1
Foamy histiocyte
33. Parkinsonism with autonomic dysfunction and orthostatic hypotension
Letterer Siwe dx
Hartnup dx
Hodgkin dx
Shy Drager syndrome
34. Aka pituitary cachexia - generalized panhypopituitarism
Wegener granulomatosis
Berger dx
Simmonds dx
Heart failure cells
35. Primary adrenal failure
Angelman syndrome
Addison disease
Simmonds dx
Henoch Schonlein Purpura
36. Mesangial matrix material acculmulations seen in nodular glomerulosclerosis seen in diabetic nephropathy
Kimmelstiel Wilson nodules
Whipple triad
Pancoast tumor
Marfan syndrome
37. Aneurysm at small artery bifurcations
Letterer Siwe dx
Whipple dx
Gerstmann Straussler
Charcot Bouchard aneurysm
38. Similar to Hurler - deficient L iduronosulfate sulfatase - accumulations of heparin sulfate and dermatan sulfate - hepatospenomegaly - micrognathia - retinal degeneration - joint stiffness - mental retardation - cardiac lesions
Hunter syndrome
Hartnup dx
Still disease
Prader willi syndrome
39. Variant of rheumatoid arthritis - splenmegally - neutropenia - RA
Brutons Agammaglobulinemia
Felty syndrome
Nelson syndrome
Beriberi
40. Aka neurofibromatosis - neurofibromas in skin - schwannomas of CN VIII - caf
Von Recklinhousen dx
Conn syndrome
Hurler syndrome
PIG A
41. Deficient sphingomyelinase - accumulation of sphingomyelin in phagocytes - foamy histiocytes in liver - spleen - lymph nodes - skin - hepatosplenomegaly - anemia fever - occasional neuro degeneration - half have cherry red spot macula
Alport syndrome
Kawasaki dx
Niemann Pick dx
McArdle syndrome
42. Gene product facilitates apoptosis
Bax
Cori dx
Hurthle cell
Nelson syndrome
43. Seen in granuloma inguinale - multiple organisms filling large histiocytes
Kimmelsteil Wilson dx
Donovan bodies
Ras oncogenes
Whipple triad
44. X linked - absence of plasma cells and serum immunoglobulins - cell mediated immunity still ok - no germinal centers - recurrent bacterial infections - resistances to fungal and viral still - btk gene defect
Buerger dx
Klinefelter syndrome
Plummer dx
Brutons Agammaglobulinemia
45. Intracytoplasmic proximal dentritic eosinophilic inclusions consisting of actin seen in Alzheimers
Hirano bodies
GNAS1
Paget dx of bone
Angelman syndrome
46. Thyroid replacement by fibrous tissue - unkown origin - mimics
Aschoff body
Arthus reaction
Reidel thyroiditis
Raynaud phenomenon
47. Gene mutated in achondroplasia (most common form of dwarfism) - located at 4p16.3
Prader willi syndrome
FGFR3
Kayser Fleischer ring
ANAs in SLE
48. Paraneoplastic synd looks like myasthenia gravis - often small cell lung CA
Wilms tumor
Lambert Eaton syndrome
Donovan bodies
Hurler syndrome
49. Variant of rheumatoid arthritis - aka juvenile rheumatoid arthritis
Chromosome 10
Aschoff body
Virchow node
Still disease
50. Hereditary nephritis associated with nerve deafness and ocular disorders - mutation in gene for the a5 chain of type IV collagen
Foamy histiocyte
Lisch nodule
Alport syndrome
Hand Schuller Christian dx