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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
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  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Osteophytes at DIP joints






2. Seen in CLL - leukemic B- cells that are fragile






3. Autosomal dominant - fatal - progressive degeneration of striatum and frontal cortex with neuronal depletion and gliosis






4. Thiamine deficiency - cerebral dysfunction - aka alcoholic encephalopathy - hemorrhagic lesions in the mamillary bodies - confusion - ataxia - ophthalmoplegia - and memory loss plus confabulation p 105 and p115






5. Associated with Wegener granulomatosis






6. Subcutaneous fibrosis of dorsum of penis






7. Dysplastic cell seen in HPV






8. Peripheral neuropathy - atrophy of muscles - wet - high output cardiac failure - DCM - AV shunting - hypervolemia






9. Impaired tubular reabsorption of tryptophan - pellagra::like manifestations






10. Myc :: neuroblastoma amplicatiion correlates inversely with degree of differentiation






11. Associated with 90% cases of ankylosing spondylitis - common in rheumatoid arthritis






12. Autosomal dominant - numerous adenomatous polyps along with osteomas and soft tissue tumors






13. Pituitary insufficiency post - partum - low TSH ACTH






14. Gene mutated in achondroplasia (most common form of dwarfism) - located at 4p16.3






15. Abnormal WT 1 gene - intersexual disorders - nephropathy - wilms tumor






16. Autoimmune hypothyroid - hurthle cells common






17. Aka infantile progressive spinal muscular atrophy - autosomal recessive - LMN disease - infants






18. Deficient glucose -6- phosphatase - accumulation of glycogen in liver and kidney - hepatomegaly - hypoglycemia






19. Deficient fibrillin (constituent of microfibrils) - arachnodactyly - ectopia lentis - aortic aneurysm - mitral valve prolapsed






20. Aka velocardiofacial syndrome and CATCH 22 syndrome - micro deletion of 22q11 - Cardiac abnormalities - Abnormal facies - T cell deficit due to thymic hypoplasia - Cleft palate - Hypocalcemia due to hypoparathyroidism - from poor development of 3rd a






21. Sphingomyelin containing phagocytes seen in Niemman::Pick dx in liver - spleen - lymph nodes and skin






22. Defective cilia - sinusitis - bronchiectasis - situs inversus - sometimes hearing loss and male sterility






23. Triad of ovarian fibroma - ascites - hydrothorax






24. Thrombotic occlusion of major hepatic veins - abnormal pain - jaundice - hepatomegaly - acites - liver failure - assoc with polycythemia vera - hepatocellular CA - and other common neoplasms - may occur as a complication of pregnancy






25. On lymph node biopsy - seen with Burkitt lymphoma






26. Infectious disorder - caused postencephalitic parkinsonism






27. Aka trisomy 13 - mental retardation - microcephaly - micropthalmia - brain abnormalities - cleft lip/palate - polydactyly - rockerbottom feet - congenital heart dx






28. Aka IgA nephropathy - deposition of IgA in mesangium - benign recurrent hematuria in kids following infection






29. Aka mucocutaneous lymph node syndrome - acute self - limited - infants and young kids - acute necrotizing vasculitis of small and medium vessels - fever hemorrhagic edema of conjunctivae - lips and oral mucosa - and cervical LAD - can cause coronary






30. Urethritis - conjunctivitis - arthritis - associated with venereal or intestinal infection






31. Seen in Down synd - small white spots on periphery of iris






32. Seen in granuloma inguinale - multiple organisms filling large histiocytes






33. Eosinophilic intracytoplasmic inclusions in hippocampus and purkinje cells seen in rabies infection






34. Tumor suppressor mutated in wilms tumor






35. Radiologic appearance of periostium in bone tumors






36. Ovarian tumor resembling bladder transitional epith






37. Similar to paget breast - sometimes related to underlying adenoCA of sweat glands






38. Associated with papillary thyroid CA






39. Similar to Dubin Johnson with no black liver






40. Follicular lymphoma IG heavy chain on 14 - bcl -2 oncogene on 18






41. Hemangioblastoma or cavernous hemangioma of cerebellum - brainstem or retina - adenomas - cysts in liver - kidney - pancreas - and other organs - increased renal cell CA - gene = short arm of chromosome 3






42. Nystagmus - intention tremor - scanning speech - seen in MS






43. Aka congenital megacolon - dilation of colon due to absence of ganglion cells






44. Nuclei arranged in horseshoe - shaped pattern about periphery of cell - characteristic of but not specific for granulomatous TB (as opposed to a foreign body giant cell that has scattered nuclei)






45. Primary aldosteronism






46. Deficient hexosaminidase A - GM2 ganglioside accumulation - especially in neurons - CNS degeneration - mental/motor deterioration - blindness - cherry red spot on macula - death by 4 years of age






47. Also seen in urine of MM - stacks of RBCs - will have high ESR






48. Gene product facilitates apoptosis






49. Philadelphia chromosome - CML bcr abl fusion c - abl on 9 - bcr on 22






50. Ring of copper deposited around iris seen in Wilson







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