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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Osteophytes at PIP joints






2. Hereditary nephritis associated with nerve deafness and ocular disorders - mutation in gene for the a5 chain of type IV collagen






3. Oncogenes that code for p21 proteins which are membrane signalers






4. Gene mutated in achondroplasia (most common form of dwarfism) - located at 4p16.3






5. Mucopolysaccharidosis - deficient a L iduronidase - accumulations of heparin sulfate and dermatan sulfate in heart - brain - liver - and other organs - progressive - hepatosplenomagaly - dwarfism - gargoyle - like facies - stubby fingers - corneal cl






6. Aka trisomy 13 - mental retardation - microcephaly - micropthalmia - brain abnormalities - cleft lip/palate - polydactyly - rockerbottom feet - congenital heart dx






7. Impaired tubular reabsorption of tryptophan - pellagra::like manifestations






8. Aka superior sulcus tumor - seen in bronchogenic CA - often with Horner's






9. Minute neutrophilic abscesses found within parakeratotic stratum corneum in psoriasis






10. Aka acute disseminated langerhans cell histiocytosis - aggressive - usually fatal - kids hepatosplenomegaly - LAD - pancytopenia - pulmonary involvement - recurrent infections






11. Deficient glucose -6- phosphatase - accumulation of glycogen in liver and kidney - hepatomegaly - hypoglycemia






12. X linked - aka immunodeficiency with thrombocytopenia and eczema - total immunoglobulins often normal - recurrent infections






13. Clear cell renal tumor seen in kids






14. Aka pituitary cachexia - generalized panhypopituitarism






15. Hemangioblastoma or cavernous hemangioma of cerebellum - brainstem or retina - adenomas - cysts in liver - kidney - pancreas - and other organs - increased renal cell CA - gene = short arm of chromosome 3






16. B Thalassemia major






17. Thiamine deficiency - cerebral dysfunction - aka alcoholic encephalopathy - hemorrhagic lesions in the mamillary bodies - confusion - ataxia - ophthalmoplegia - and memory loss plus confabulation p 105 and p115






18. Aka osteopetrosis - marble bone dx - dense skeleton - failure of osteoclastic activity






19. DsDNA antibodies and Sm Smith antigen = highly specific for SLE






20. Tumor suppressor mutated in wilms tumor






21. Catastrophic adrenal insuff and vascular collapse - hemorrhagic necrosis of adrenal cortex






22. Seen in urine of patients with multiple myeloma - Ig light chain either k or l






23. Aka IgA nephropathy - deposition of IgA in mesangium - benign recurrent hematuria in kids following infection






24. Pituitary insufficiency post - partum - low TSH ACTH






25. Development of large pituitary adenomas following bilat adrenalectomy






26. Aka allergic granulomatous angiitis - necrotizing vasculitis - variant of polyarteritis nodosa - involves pulmonary vasculature - peripheral eosinophilia - and asthma






27. Defective cilia - sinusitis - bronchiectasis - situs inversus - sometimes hearing loss and male sterility






28. Deficient hexosaminidase A - GM2 ganglioside accumulation - especially in neurons - CNS degeneration - mental/motor deterioration - blindness - cherry red spot on macula - death by 4 years of age






29. Small round eosinophilic masses found in dieing hepatocytes often containing chromatin remnants seen in viral hepatitis






30. At least 2 X and one Y - hypogonadism - tall - gynecomastia - low testosterone - high pituitary gonadotropins - infertility -






31. Peripheral neuropathy - atrophy of muscles - wet - high output cardiac failure - DCM - AV shunting - hypervolemia






32. Acute inflammatory demyelinating dx primarily involving peripheral nerves






33. Retinoblastoma on chromosome 13






34. Combination of hyperthyroidism - nodular goiter - absence of exophthalmos






35. Also seen in urine of MM - stacks of RBCs - will have high ESR






36. Similar to Hurler - deficient L iduronosulfate sulfatase - accumulations of heparin sulfate and dermatan sulfate - hepatospenomegaly - micrognathia - retinal degeneration - joint stiffness - mental retardation - cardiac lesions






37. Myc :: neuroblastoma amplicatiion correlates inversely with degree of differentiation






38. Associated with breast alone (isn't one of these associated with prostate? Check)






39. Port wine stain on face - ipsilateral glaucoma - vascular lesions of ocular choroidal tissue - extensive hemangiomatous involvement of meninges






40. Sphingomyelin containing phagocytes seen in Niemman::Pick dx in liver - spleen - lymph nodes and skin






41. Paraneoplastic synd looks like myasthenia gravis - often small cell lung CA






42. Aka osteitis deformans - increased osteoclastic and osteoblastic activity






43. Seen in insulinoma - episodic hyperinsulinemia and hypoglycemia - CNS dysfunction - reversal of CNS probs with administration of glucose






44. Severe unconj hyperbilirubinemia due to deficient glucuronyl transferase






45. Hemorrhagic urticaria of extensor surgaces of arms - legs - and buttocks - with fever - arthralgias - and GI renal involvement similar to IgA nephropathy - associated with URIs






46. This comes in a wet variety and a dry one - they are both Vit B1 thiamine deficiency






47. Autosomal recessive - unusually large platelets - lack of 'GPIb IX V'






48. Thrombotic occlusion of major hepatic veins - abnormal pain - jaundice - hepatomegaly - acites - liver failure - assoc with polycythemia vera - hepatocellular CA - and other common neoplasms - may occur as a complication of pregnancy






49. 2/neu :: oncogene (aka c - erbB2) - in breast cancer = poor prognosis






50. Single erythematous plaque on shaft of penis or scrotum