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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Associated with papillary thyroid CA






2. Small follicles filled with eosinophilic secretion - diagnostic feature of granulose cell tumor






3. Tumor suppressor mutated in wilms tumor






4. Associated with 90% cases of ankylosing spondylitis - common in rheumatoid arthritis






5. Associated with breast alone (isn't one of these associated with prostate? Check)






6. Aka hereditary hemorrhagic telangectasia - telangectasias in skin and mucous membranes - epistaxis - GI bleeds






7. X linked - absence of plasma cells and serum immunoglobulins - cell mediated immunity still ok - no germinal centers - recurrent bacterial infections - resistances to fungal and viral still - btk gene defect






8. Aka lentigo maligna - precursor to lentigo maligna melanoma






9. Development of large pituitary adenomas following bilat adrenalectomy






10. Aspirin toxicity seen in kids after acute febrile viral dx - microvesicular fatty change in liver and encephalopathy






11. B1 thiamine - B2 riboflavin - B3 niacin - B6 pyridoxine - B12 cobalamin - C ascorbic acid - D calciferol - E a::tocopherol






12. Deficient glucocerebrosidase - accumulation of glucocerebroside in cells of mononuclear phagocyte system 3 types ::






13. B Thalassemia major






14. Similar to Dubin Johnson with no black liver






15. Variant of rheumatoid arthritis - splenmegally - neutropenia - RA






16. Aka polycystic ovary syndrome - young women - amenorrhea - infertility - obesity - hirsutism






17. Aka mucocutaneous lymph node syndrome - acute self - limited - infants and young kids - acute necrotizing vasculitis of small and medium vessels - fever hemorrhagic edema of conjunctivae - lips and oral mucosa - and cervical LAD - can cause coronary






18. Mucopolysaccharidosis - deficient a L iduronidase - accumulations of heparin sulfate and dermatan sulfate in heart - brain - liver - and other organs - progressive - hepatosplenomagaly - dwarfism - gargoyle - like facies - stubby fingers - corneal cl






19. Severe unconj hyperbilirubinemia due to deficient glucuronyl transferase






20. Single erythematous plaque on shaft of penis or scrotum






21. On lymph node biopsy - seen with Burkitt lymphoma






22. Autoimmune hypothyroid - hurthle cells common






23. Follicular lymphoma IG heavy chain on 14 - bcl -2 oncogene on 18






24. Tumor suppressor common in familial polyposis coli and adenoCA of colon as well as other tumors






25. Vaginal epithelial cell with stippled appearance due to adherent coccobacilli






26. Mutation here causes pseudohypoparathyroidism






27. Protooncogene mutated in medulary thyroid CA (MENII)






28. Deficient glucose -6- phosphatase - accumulation of glycogen in liver and kidney - hepatomegaly - hypoglycemia






29. Seen in urine of patients with multiple myeloma - Ig light chain either k or l






30. Aka antiglomerular basement membrane dx - antibodies against alveolar and glomerular basement membranes - linear immunoflorescence






31. This comes in a wet variety and a dry one - they are both Vit B1 thiamine deficiency






32. Aka velocardiofacial syndrome and CATCH 22 syndrome - micro deletion of 22q11 - Cardiac abnormalities - Abnormal facies - T cell deficit due to thymic hypoplasia - Cleft palate - Hypocalcemia due to hypoparathyroidism - from poor development of 3rd a






33. Diffuse nodular diabetic glomerulosclerosis






34. Hamartomatous polyps in colon and small intest - freckles on lips - hands - genitalia - higher incidence of adeno CA of colon and other malignancies - stomach - breast - ovaries






35. Vasosmasm of small vessels - most often in fingers - seen with autoimmune dx like SLE - scleroderma and others (R in CREST) - recurrent vasospasm - always secondary to underlying disorder






36. Small round blue cell tumor of bone - long bones - kids - 11:22 transloc






37. Aka infantile progressive spinal muscular atrophy - autosomal recessive - LMN disease - infants






38. Appears as multiple wart - like lesions resembling condyloma accuminatum






39. Sphingomyelin containing phagocytes seen in Niemman::Pick dx in liver - spleen - lymph nodes and skin






40. Autosomal dominant - numerous adenomatous polyps along with osteomas and soft tissue tumors






41. Mesangial matrix material acculmulations seen in nodular glomerulosclerosis seen in diabetic nephropathy






42. Malabsorption syndrome - Tropheryma wippelii bacilli - small intestine commonly affected - arthralgias - cardiac - and neuro symptoms






43. Defective in x- linked brutons agammaglobulinemia - B- cell tyrosine kinase






44. X linked - aka immunodeficiency with thrombocytopenia and eczema - total immunoglobulins often normal - recurrent infections






45. Manifestation of lymphplasmocytic lymphoma - B cell neoplasm






46. Autosomal dominant - fatal - progressive degeneration of striatum and frontal cortex with neuronal depletion and gliosis






47. DsDNA antibodies and Sm Smith antigen = highly specific for SLE






48. Defective cilia - sinusitis - bronchiectasis - situs inversus - sometimes hearing loss and male sterility






49. Transloc seen in ewing sarcoma






50. Tennis racket shaped cytoplasmic inclusion seen in langerhans cells (so also seen in langerhan cell histiocytosis)