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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Binucleated or multinucleated giant cell seen in Hodgkin dx






2. Aka mucocutaneous lymph node syndrome - acute self - limited - infants and young kids - acute necrotizing vasculitis of small and medium vessels - fever hemorrhagic edema of conjunctivae - lips and oral mucosa - and cervical LAD - can cause coronary






3. Defective cilia - sinusitis - bronchiectasis - situs inversus - sometimes hearing loss and male sterility






4. Aka subcortical leukoencephalopathy - assoc with HTN - multiple lacunar infarcts and progressive demyelination in subcortical area






5. Autosomal recessive - conj hyperbilirubinemia - defect in bili transport - black color to liver






6. Appears as multiple wart - like lesions resembling condyloma accuminatum






7. Impaired tubular reabsorption of tryptophan - pellagra::like manifestations






8. X linked - absence of plasma cells and serum immunoglobulins - cell mediated immunity still ok - no germinal centers - recurrent bacterial infections - resistances to fungal and viral still - btk gene defect






9. Aka congenital megacolon - dilation of colon due to absence of ganglion cells






10. Materal transmission del(15)(q11q13) - aka happy puppet syndrome - mental retardation - ataxia - seizures - inappropriate laughter






11. Catastrophic adrenal insuff and vascular collapse - hemorrhagic necrosis of adrenal cortex






12. Oligohydramnios causes fetus to be smashed






13. Aka thromboangiitis obliterans - acute inflame of small and med arteries of extremities - extending to adjacent veins and nerves - young jewish men - painful ischemic dx - worse with smoking






14. Clear cell renal tumor seen in kids






15. Aka neurofibromatosis - neurofibromas in skin - schwannomas of CN VIII - caf






16. Tumor suppressor mutated in breast and ovary






17. Downward displacement of cerebellar tonsils and medulla through foramen magnum






18. Aka pituitary cachexia - generalized panhypopituitarism






19. Tumor suppressor mutated in Von Recklinhousen






20. Deficient a1 -4 glucosidase - accumulation of glycogen in liver - heart - skeletal muscle - cardiomegaly - muscle hypotonia - spelnomegaly - intractable hypoglycemia - death from cardiorespiratory failure before age 3






21. Different in that it is the primary disorder - recurrent vasospasm of small arteries and venules - pallor - cyanosis - fingers and toes - young healthy women






22. Seen in CLL - leukemic B- cells that are fragile






23. Variant of rheumatoid arthritis - splenmegally - neutropenia - RA






24. This comes in a wet variety and a dry one - they are both Vit B1 thiamine deficiency






25. Deficient debranching enzyme amylo -1 -6- glucosidase - glycogen in liver - heart - skeletal muscle - stunted growth - hepatomegaly - hypoglycemia






26. = MEN2a






27. Asbestosis - yellow - brown - rod shaped body with clubbed ends - stain with Prussian blue






28. Autoimmune hypothyroid - hurthle cells common






29. Autoimmune thyroiditis - hyperthyroid - exophthalmos - increased in HLA DR3 and HLA B8 pos people






30. On lymph node biopsy - seen with Burkitt lymphoma






31. Development of large pituitary adenomas following bilat adrenalectomy






32. Deficient fibrillin (constituent of microfibrils) - arachnodactyly - ectopia lentis - aortic aneurysm - mitral valve prolapsed






33. Autosomal dominant - numerous adenomatous polyps along with osteomas and soft tissue tumors






34. Paternal transmission del (15)(q11q13) - hypogonad - hypotonia - mental retardation - behavior probs - uncrontrolled appetite






35. Mucinous cell - characteristic of stomach CA met to ovary (krukenberg tumor)






36. Superclavicular lymph node identifying metastatic stomach CA






37. Iron deficient anemia associated with upper::esophageal web






38. Hamartomatous polyps in colon and small intest - freckles on lips - hands - genitalia - higher incidence of adeno CA of colon and other malignancies - stomach - breast - ovaries






39. Malignant lymphoma with features resembling inflammatory disorder - young men - Reed Sternburg cells






40. Small round eosinophilic masses found in dieing hepatocytes often containing chromatin remnants seen in viral hepatitis






41. Gene product facilitates apoptosis - decreases bcl::2 and increases Bax






42. Gene product facilitates apoptosis






43. Aka pulseless dx - inflammation and stenosis of medium and large sized arteries - often aortic arch thus aortic arch syndrome






44. Infectious disorder - caused postencephalitic parkinsonism






45. Vasosmasm of small vessels - most often in fingers - seen with autoimmune dx like SLE - scleroderma and others (R in CREST) - recurrent vasospasm - always secondary to underlying disorder






46. Philadelphia chromosome - CML bcr abl fusion c - abl on 9 - bcr on 22






47. B1 thiamine - B2 riboflavin - B3 niacin - B6 pyridoxine - B12 cobalamin - C ascorbic acid - D calciferol - E a::tocopherol






48. Primary adrenal failure






49. Tennis racket shaped cytoplasmic inclusion seen in langerhans cells (so also seen in langerhan cell histiocytosis)






50. Acute promyelocytic leukemia PML gene on 15 and RARa on 17