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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Thyroid replacement by fibrous tissue - unkown origin - mimics






2. At least 2 X and one Y - hypogonadism - tall - gynecomastia - low testosterone - high pituitary gonadotropins - infertility -






3. Sphingomyelin containing phagocytes seen in Niemman::Pick dx in liver - spleen - lymph nodes and skin






4. Aka neurofibromatosis - neurofibromas in skin - schwannomas of CN VIII - caf






5. Paracentric inversion or translocation with 17 associated with papillary thyroid CA






6. Deficient hypoxanthine::guanine phosphoribosyltransferase (HGPRT) - low purine metabolism - high uric acid - thus gout - mental retardation - choreoathetosis - spasticity - self mutilation - aggressiveness






7. Protooncogene mutated in medulary thyroid CA (MENII)






8. Nuclei arranged in horseshoe - shaped pattern about periphery of cell - characteristic of but not specific for granulomatous TB (as opposed to a foreign body giant cell that has scattered nuclei)






9. Autosomal recessive - unusually large platelets - lack of 'GPIb IX V'






10. Transloc seen in ewing sarcoma






11. B Thalassemia major






12. Deficient debranching enzyme amylo -1 -6- glucosidase - glycogen in liver - heart - skeletal muscle - stunted growth - hepatomegaly - hypoglycemia






13. Aka antiglomerular basement membrane dx - antibodies against alveolar and glomerular basement membranes - linear immunoflorescence






14. Catastrophic adrenal insuff and vascular collapse - hemorrhagic necrosis of adrenal cortex






15. Aka trisomy 18 - mental retardation - prominent occiput - micrognathia (small jaw) - low::set ears - rocker::bottom feet - finger deformities - congenital heart dx






16. Epithelial cells with eosinophilc granular cytoplasm seen in hashimoto






17. Aka congenital megacolon - dilation of colon due to absence of ganglion cells






18. Primary adrenal failure






19. Port wine stain on face - ipsilateral glaucoma - vascular lesions of ocular choroidal tissue - extensive hemangiomatous involvement of meninges






20. Hemorrhagic urticaria of extensor surgaces of arms - legs - and buttocks - with fever - arthralgias - and GI renal involvement similar to IgA nephropathy - associated with URIs






21. Aka thromboangiitis obliterans - acute inflame of small and med arteries of extremities - extending to adjacent veins and nerves - young jewish men - painful ischemic dx - worse with smoking






22. Peripheral neuropathy - atrophy of muscles - wet - high output cardiac failure - DCM - AV shunting - hypervolemia






23. Intra::alveolar hemosiderin - laden macrophages caused by RBCs from capillary rupture 2* to pulmonary HTN






24. Autosomal recessive - hepatitis - accumulation of copper due to transport problem - low ceruloplasmin seen - kayser fleischer rings in eyes






25. Triad of ovarian fibroma - ascites - hydrothorax






26. Deficient fibrillin (constituent of microfibrils) - arachnodactyly - ectopia lentis - aortic aneurysm - mitral valve prolapsed






27. Aka chronic progressive histiocytosis - not as bad as Letterer Siwe






28. Mucopolysaccharidosis - deficient a L iduronidase - accumulations of heparin sulfate and dermatan sulfate in heart - brain - liver - and other organs - progressive - hepatosplenomagaly - dwarfism - gargoyle - like facies - stubby fingers - corneal cl






29. Subcutaneous fibrosis of dorsum of penis






30. Deficient hexosaminidase A - GM2 ganglioside accumulation - especially in neurons - CNS degeneration - mental/motor deterioration - blindness - cherry red spot on macula - death by 4 years of age






31. Mesangial matrix material acculmulations seen in nodular glomerulosclerosis seen in diabetic nephropathy






32. Paternal transmission del (15)(q11q13) - hypogonad - hypotonia - mental retardation - behavior probs - uncrontrolled appetite






33. Hamartomatous polyps in colon and small intest - freckles on lips - hands - genitalia - higher incidence of adeno CA of colon and other malignancies - stomach - breast - ovaries






34. Gene mutated in achondroplasia (most common form of dwarfism) - located at 4p16.3






35. Diffuse nodular diabetic glomerulosclerosis






36. Autoimmune hypothyroid - hurthle cells common






37. Hemihypertrophy - macroglossia - organomegaly - neonatal hypoglycemia - various embryonal tumors - deleted WT 2 gene






38. Aggressive B- cell lymphoma - EBV - starry sky appearance - c myc






39. Philadelphia chromosome - CML bcr abl fusion c - abl on 9 - bcr on 22






40. Tumor suppressor mutated in Von Recklinhousen






41. On lymph node biopsy - seen with Burkitt lymphoma






42. Aka pulseless dx - inflammation and stenosis of medium and large sized arteries - often aortic arch thus aortic arch syndrome






43. Materal transmission del(15)(q11q13) - aka happy puppet syndrome - mental retardation - ataxia - seizures - inappropriate laughter






44. Aneurysm at small artery bifurcations






45. Intracytoplasmic proximal dentritic eosinophilic inclusions consisting of actin seen in Alzheimers






46. Aka IgA nephropathy - deposition of IgA in mesangium - benign recurrent hematuria in kids following infection






47. 45 XO - female hypogonadism - hypothyroid - short - webbed neck - 1* amenorrhea p52






48. Vasosmasm of small vessels - most often in fingers - seen with autoimmune dx like SLE - scleroderma and others (R in CREST) - recurrent vasospasm - always secondary to underlying disorder






49. Malignant lymphoma with features resembling inflammatory disorder - young men - Reed Sternburg cells






50. Tumor suppressor mutated in breast and ovary







Sorry!:) No result found.

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