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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Tumor suppressor mutated in breast and ovary






2. Aneurysm at small artery bifurcations






3. Small round blue cell tumor of bone - long bones - kids - 11:22 transloc






4. Port wine stain on face - ipsilateral glaucoma - vascular lesions of ocular choroidal tissue - extensive hemangiomatous involvement of meninges






5. Scheinker syndrome :: prion dx - fatal familial insomnia






6. Ovarian tumor resembling bladder transitional epith






7. Associated with papillary thyroid CA






8. Area of focal interstitial myocardial inflammation characterized by fragmented collagen and fibrinoid material - by large cells (Anitschkow myocytes) and occasional multinucleated giant cells (Aschoff cells)






9. On lymph node biopsy - seen with Burkitt lymphoma






10. Metastatic stomach CA to ovary






11. Tumor suppressor common in familial polyposis coli and adenoCA of colon as well as other tumors






12. Thrombotic occlusion of major hepatic veins - abnormal pain - jaundice - hepatomegaly - acites - liver failure - assoc with polycythemia vera - hepatocellular CA - and other common neoplasms - may occur as a complication of pregnancy






13. Nystagmus - intention tremor - scanning speech - seen in MS






14. Ring of copper deposited around iris seen in Wilson






15. Autosomal dominant - fatal - progressive degeneration of striatum and frontal cortex with neuronal depletion and gliosis






16. Aka lentigo maligna - precursor to lentigo maligna melanoma






17. Aka polycystic ovary syndrome - young women - amenorrhea - infertility - obesity - hirsutism






18. Aka pulseless dx - inflammation and stenosis of medium and large sized arteries - often aortic arch thus aortic arch syndrome






19. Aka angiokeratoma corporis diffusum universal - deficient a::galactosidase A - accumulate ceramide trihexoside - skin lesions angiokeratomas - fever - burning pain in extremities - cardiovascular and cerebrovascular involvement - death as adult by re






20. Aka infantile progressive spinal muscular atrophy - autosomal recessive - LMN disease - infants






21. At least 2 X and one Y - hypogonadism - tall - gynecomastia - low testosterone - high pituitary gonadotropins - infertility -






22. Aka chronic progressive histiocytosis - not as bad as Letterer Siwe






23. Manifestation of lymphplasmocytic lymphoma - B cell neoplasm






24. Parkinsonism with autonomic dysfunction and orthostatic hypotension






25. Tumor suppressor mutated in wilms tumor






26. Aka osteopetrosis - marble bone dx - dense skeleton - failure of osteoclastic activity






27. Aka trisomy 18 - mental retardation - prominent occiput - micrognathia (small jaw) - low::set ears - rocker::bottom feet - finger deformities - congenital heart dx






28. Seen in insulinoma - episodic hyperinsulinemia and hypoglycemia - CNS dysfunction - reversal of CNS probs with administration of glucose






29. Variant of rheumatoid arthritis - splenmegally - neutropenia - RA






30. Aka thromboangiitis obliterans - acute inflame of small and med arteries of extremities - extending to adjacent veins and nerves - young jewish men - painful ischemic dx - worse with smoking






31. Hemihypertrophy - macroglossia - organomegaly - neonatal hypoglycemia - various embryonal tumors - deleted WT 2 gene






32. Autosomal recessive - hepatitis - accumulation of copper due to transport problem - low ceruloplasmin seen - kayser fleischer rings in eyes






33. Hereditary nephritis associated with nerve deafness and ocular disorders - mutation in gene for the a5 chain of type IV collagen






34. Small round eosinophilic masses found in dieing hepatocytes often containing chromatin remnants seen in viral hepatitis






35. Polyostotic fibrous dysplasia - precocious puberty - caf






36. Burkitts c::myc is on 8 - IG heavy chain is on 14






37. Gene mutated in achondroplasia (most common form of dwarfism) - located at 4p16.3






38. Aka allergic granulomatous angiitis - necrotizing vasculitis - variant of polyarteritis nodosa - involves pulmonary vasculature - peripheral eosinophilia - and asthma






39. Urethritis - conjunctivitis - arthritis - associated with venereal or intestinal infection






40. Aka IgA nephropathy - deposition of IgA in mesangium - benign recurrent hematuria in kids following infection






41. Hemorrhagic urticaria of extensor surgaces of arms - legs - and buttocks - with fever - arthralgias - and GI renal involvement similar to IgA nephropathy - associated with URIs






42. Occurs in SLE - small vegitations on either or both surfaces of valves






43. Osteophytes at DIP joints






44. Sphingomyelin containing phagocytes seen in Niemman::Pick dx in liver - spleen - lymph nodes and skin






45. Small follicles filled with eosinophilic secretion - diagnostic feature of granulose cell tumor






46. Binucleated or multinucleated giant cell seen in Hodgkin dx






47. Seen in Down synd - small white spots on periphery of iris






48. Aka acute disseminated langerhans cell histiocytosis - aggressive - usually fatal - kids hepatosplenomegaly - LAD - pancytopenia - pulmonary involvement - recurrent infections






49. B1 thiamine - B2 riboflavin - B3 niacin - B6 pyridoxine - B12 cobalamin - C ascorbic acid - D calciferol - E a::tocopherol






50. Autoimmune hypothyroid - hurthle cells common







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