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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
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  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Ovarian tumor resembling bladder transitional epith






2. Adenomatous polyps with tumors of CNS






3. Iron deficient anemia associated with upper::esophageal web






4. X linked - aka immunodeficiency with thrombocytopenia and eczema - total immunoglobulins often normal - recurrent infections






5. Aka trisomy 13 - mental retardation - microcephaly - micropthalmia - brain abnormalities - cleft lip/palate - polydactyly - rockerbottom feet - congenital heart dx






6. Autoimmune thyroiditis - hyperthyroid - exophthalmos - increased in HLA DR3 and HLA B8 pos people






7. Intracytoplasmic proximal dentritic eosinophilic inclusions consisting of actin seen in Alzheimers






8. Gene product facilitates apoptosis






9. Paternal transmission del (15)(q11q13) - hypogonad - hypotonia - mental retardation - behavior probs - uncrontrolled appetite






10. Seen in urine of patients with multiple myeloma - Ig light chain either k or l






11. Vasosmasm of small vessels - most often in fingers - seen with autoimmune dx like SLE - scleroderma and others (R in CREST) - recurrent vasospasm - always secondary to underlying disorder






12. Paracentric inversion or translocation with 17 associated with papillary thyroid CA






13. Hemihypertrophy - macroglossia - organomegaly - neonatal hypoglycemia - various embryonal tumors - deleted WT 2 gene






14. Aka polycystic ovary syndrome - young women - amenorrhea - infertility - obesity - hirsutism






15. Myc :: neuroblastoma amplicatiion correlates inversely with degree of differentiation






16. Deficient sphingomyelinase - accumulation of sphingomyelin in phagocytes - foamy histiocytes in liver - spleen - lymph nodes - skin - hepatosplenomegaly - anemia fever - occasional neuro degeneration - half have cherry red spot macula






17. Transloc seen in ewing sarcoma






18. Seen in insulinoma - episodic hyperinsulinemia and hypoglycemia - CNS dysfunction - reversal of CNS probs with administration of glucose






19. Infectious disorder - caused postencephalitic parkinsonism






20. Tumor suppressor common in familial polyposis coli and adenoCA of colon as well as other tumors






21. Deficient muscle phosphorylase - glycogen in skeletal muscle - cramps with exertion






22. Materal transmission del(15)(q11q13) - aka happy puppet syndrome - mental retardation - ataxia - seizures - inappropriate laughter






23. Aka mucocutaneous lymph node syndrome - acute self - limited - infants and young kids - acute necrotizing vasculitis of small and medium vessels - fever hemorrhagic edema of conjunctivae - lips and oral mucosa - and cervical LAD - can cause coronary






24. Autosomal recessive - unusually large platelets - lack of 'GPIb IX V'






25. Aka pulseless dx - inflammation and stenosis of medium and large sized arteries - often aortic arch thus aortic arch syndrome






26. Aspirin toxicity seen in kids after acute febrile viral dx - microvesicular fatty change in liver and encephalopathy






27. Similar to Hurler - deficient L iduronosulfate sulfatase - accumulations of heparin sulfate and dermatan sulfate - hepatospenomegaly - micrognathia - retinal degeneration - joint stiffness - mental retardation - cardiac lesions






28. Aka acute disseminated langerhans cell histiocytosis - aggressive - usually fatal - kids hepatosplenomegaly - LAD - pancytopenia - pulmonary involvement - recurrent infections






29. Eosinophilic intracytoplasmic inclusions in hippocampus and purkinje cells seen in rabies infection






30. Mutation = paroxysmal nocturnal hemoglobinuria






31. Minute neutrophilic abscesses found within parakeratotic stratum corneum in psoriasis






32. Unknown etiology - necrotizing granulomatous vasculitis of small to medium sized vessels of the respiratory tract - kidneys - and other organs - circulating C- ANCAs






33. Aka thromboangiitis obliterans - acute inflame of small and med arteries of extremities - extending to adjacent veins and nerves - young jewish men - painful ischemic dx - worse with smoking






34. Appears as multiple wart - like lesions resembling condyloma accuminatum






35. Malignant lymphoma with features resembling inflammatory disorder - young men - Reed Sternburg cells






36. Osteophytes at DIP joints






37. Aneurysm at small artery bifurcations






38. Retinoblastoma on chromosome 13






39. Parkinsonism with autonomic dysfunction and orthostatic hypotension






40. Different in that it is the primary disorder - recurrent vasospasm of small arteries and venules - pallor - cyanosis - fingers and toes - young healthy women






41. DsDNA antibodies and Sm Smith antigen = highly specific for SLE






42. Development of large pituitary adenomas following bilat adrenalectomy






43. Seen in granuloma inguinale - multiple organisms filling large histiocytes






44. B1 thiamine - B2 riboflavin - B3 niacin - B6 pyridoxine - B12 cobalamin - C ascorbic acid - D calciferol - E a::tocopherol






45. Thiamine deficiency - cerebral dysfunction - aka alcoholic encephalopathy - hemorrhagic lesions in the mamillary bodies - confusion - ataxia - ophthalmoplegia - and memory loss plus confabulation p 105 and p115






46. Diffuse nodular diabetic glomerulosclerosis






47. Downward displacement of cerebellar tonsils and medulla through foramen magnum






48. Hemorrhagic urticaria of extensor surgaces of arms - legs - and buttocks - with fever - arthralgias - and GI renal involvement similar to IgA nephropathy - associated with URIs






49. Mutation here causes pseudohypoparathyroidism






50. Hamartomatous polyps in colon and small intest - freckles on lips - hands - genitalia - higher incidence of adeno CA of colon and other malignancies - stomach - breast - ovaries







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