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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Defective cilia - sinusitis - bronchiectasis - situs inversus - sometimes hearing loss and male sterility






2. Intracytoplasmic proximal dentritic eosinophilic inclusions consisting of actin seen in Alzheimers






3. Intra::alveolar hemosiderin - laden macrophages caused by RBCs from capillary rupture 2* to pulmonary HTN






4. Tumor suppressor common in familial polyposis coli and adenoCA of colon as well as other tumors






5. Clear cell renal tumor seen in kids






6. Pituitary insufficiency post - partum - low TSH ACTH






7. Gene product facilitates apoptosis






8. Small round blue cell tumor of bone - long bones - kids - 11:22 transloc






9. Paracentric inversion or translocation with 17 associated with papillary thyroid CA






10. Dysplastic cell seen in HPV






11. Renal tubular dysfunction - impaired reabsorption of glucose - amino acids - phosphate - and bicarb thus glycosuria - hyperphosphaturia - hypophosphatemia - aminoaciduria - systemic acidosis






12. Hemihypertrophy - macroglossia - organomegaly - neonatal hypoglycemia - various embryonal tumors - deleted WT 2 gene






13. Acute inflammatory demyelinating dx primarily involving peripheral nerves






14. Aka hereditary hemorrhagic telangectasia - telangectasias in skin and mucous membranes - epistaxis - GI bleeds






15. Deficient glucocerebrosidase - accumulation of glucocerebroside in cells of mononuclear phagocyte system 3 types ::






16. DsDNA antibodies and Sm Smith antigen = highly specific for SLE






17. Hemorrhagic urticaria of extensor surgaces of arms - legs - and buttocks - with fever - arthralgias - and GI renal involvement similar to IgA nephropathy - associated with URIs






18. Aka pulseless dx - inflammation and stenosis of medium and large sized arteries - often aortic arch thus aortic arch syndrome






19. Adenomatous polyps with tumors of CNS






20. Aka infantile progressive spinal muscular atrophy - autosomal recessive - LMN disease - infants






21. On lymph node biopsy - seen with Burkitt lymphoma






22. Sphingomyelin containing phagocytes seen in Niemman::Pick dx in liver - spleen - lymph nodes and skin






23. Port wine stain on face - ipsilateral glaucoma - vascular lesions of ocular choroidal tissue - extensive hemangiomatous involvement of meninges






24. Nuclei arranged in horseshoe - shaped pattern about periphery of cell - characteristic of but not specific for granulomatous TB (as opposed to a foreign body giant cell that has scattered nuclei)






25. Aspirin toxicity seen in kids after acute febrile viral dx - microvesicular fatty change in liver and encephalopathy






26. Metastatic stomach CA to ovary






27. Lots of tumors - breast CA - soft tissue sarc - brain tumors - leukemias - has loss of p53 tumor suppressor gene






28. Similar to Dubin Johnson with no black liver






29. Hereditary nonpolyposis colon cancer - DNA repair genes messed up






30. Superclavicular lymph node identifying metastatic stomach CA






31. Associated with Wegener granulomatosis






32. Aka allergic granulomatous angiitis - necrotizing vasculitis - variant of polyarteritis nodosa - involves pulmonary vasculature - peripheral eosinophilia - and asthma






33. Tumor suppressor mutated in wilms tumor






34. Ring of copper deposited around iris seen in Wilson






35. Pigmented iris hamartoma seen in neurofibromatosis






36. B Thalassemia major






37. Also seen in urine of MM - stacks of RBCs - will have high ESR






38. Chromosome 19 - allele common in alzheimers






39. Seen in CLL - leukemic B- cells that are fragile






40. Manifestation of lymphplasmocytic lymphoma - B cell neoplasm






41. Abnormal WT 1 gene - intersexual disorders - nephropathy - wilms tumor






42. Myc :: neuroblastoma amplicatiion correlates inversely with degree of differentiation






43. Acute promyelocytic leukemia PML gene on 15 and RARa on 17






44. Seen in insulinoma - episodic hyperinsulinemia and hypoglycemia - CNS dysfunction - reversal of CNS probs with administration of glucose






45. Hereditary nephritis associated with nerve deafness and ocular disorders - mutation in gene for the a5 chain of type IV collagen






46. Paraneoplastic synd looks like myasthenia gravis - often small cell lung CA






47. Aka congenital megacolon - dilation of colon due to absence of ganglion cells






48. Aka trisomy 13 - mental retardation - microcephaly - micropthalmia - brain abnormalities - cleft lip/palate - polydactyly - rockerbottom feet - congenital heart dx






49. Peripheral neuropathy - atrophy of muscles - wet - high output cardiac failure - DCM - AV shunting - hypervolemia






50. Similar to Hurler - deficient L iduronosulfate sulfatase - accumulations of heparin sulfate and dermatan sulfate - hepatospenomegaly - micrognathia - retinal degeneration - joint stiffness - mental retardation - cardiac lesions