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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Peripheral neuropathy - atrophy of muscles - wet - high output cardiac failure - DCM - AV shunting - hypervolemia






2. Aka thromboangiitis obliterans - acute inflame of small and med arteries of extremities - extending to adjacent veins and nerves - young jewish men - painful ischemic dx - worse with smoking






3. Gene product inhibits apoptosis






4. Diffuse nodular diabetic glomerulosclerosis






5. Aka trisomy 18 - mental retardation - prominent occiput - micrognathia (small jaw) - low::set ears - rocker::bottom feet - finger deformities - congenital heart dx






6. Aka congenital megacolon - dilation of colon due to absence of ganglion cells






7. Aka neurofibromatosis - neurofibromas in skin - schwannomas of CN VIII - caf






8. Asbestosis - yellow - brown - rod shaped body with clubbed ends - stain with Prussian blue






9. Hemorrhagic urticaria of extensor surgaces of arms - legs - and buttocks - with fever - arthralgias - and GI renal involvement similar to IgA nephropathy - associated with URIs






10. Manifestation of lymphplasmocytic lymphoma - B cell neoplasm






11. Urethritis - conjunctivitis - arthritis - associated with venereal or intestinal infection






12. Gene product facilitates apoptosis






13. Adenomatous polyps with tumors of CNS






14. Triad of ovarian fibroma - ascites - hydrothorax






15. Seen in granuloma inguinale - multiple organisms filling large histiocytes






16. X linked - aka immunodeficiency with thrombocytopenia and eczema - total immunoglobulins often normal - recurrent infections






17. Lots of tumors - breast CA - soft tissue sarc - brain tumors - leukemias - has loss of p53 tumor suppressor gene






18. Renal tubular dysfunction - impaired reabsorption of glucose - amino acids - phosphate - and bicarb thus glycosuria - hyperphosphaturia - hypophosphatemia - aminoaciduria - systemic acidosis






19. Oncogenes that code for p21 proteins which are membrane signalers






20. At least 2 X and one Y - hypogonadism - tall - gynecomastia - low testosterone - high pituitary gonadotropins - infertility -






21. B1 thiamine - B2 riboflavin - B3 niacin - B6 pyridoxine - B12 cobalamin - C ascorbic acid - D calciferol - E a::tocopherol






22. Pigmented iris hamartoma seen in neurofibromatosis






23. Tumor suppressor mutated in Von Recklinhousen






24. Thyroid replacement by fibrous tissue - unkown origin - mimics






25. Paraneoplastic synd looks like myasthenia gravis - often small cell lung CA






26. Transloc seen in ewing sarcoma






27. 5p chromosome deletion - severe mental retardation - microcephaly - catlike cry - low birth weight - round face - hypertelorism (wide eyes)






28. Combination of hyperthyroidism - nodular goiter - absence of exophthalmos






29. Gene product facilitates apoptosis - decreases bcl::2 and increases Bax






30. 2/neu :: oncogene (aka c - erbB2) - in breast cancer = poor prognosis






31. Hamartomatous polyps in colon and small intest - freckles on lips - hands - genitalia - higher incidence of adeno CA of colon and other malignancies - stomach - breast - ovaries






32. Protooncogene mutated in medulary thyroid CA (MENII)






33. 45 XO - female hypogonadism - hypothyroid - short - webbed neck - 1* amenorrhea p52






34. Ring of copper deposited around iris seen in Wilson






35. Myc :: neuroblastoma amplicatiion correlates inversely with degree of differentiation






36. = MEN2a






37. Seen in urine of patients with multiple myeloma - Ig light chain either k or l






38. Small round blue cell tumor of bone - long bones - kids - 11:22 transloc






39. Aneurysm at small artery bifurcations






40. Aka allergic granulomatous angiitis - necrotizing vasculitis - variant of polyarteritis nodosa - involves pulmonary vasculature - peripheral eosinophilia - and asthma






41. Follicular lymphoma IG heavy chain on 14 - bcl -2 oncogene on 18






42. Sphingomyelin containing phagocytes seen in Niemman::Pick dx in liver - spleen - lymph nodes and skin






43. Tumor suppressor common in familial polyposis coli and adenoCA of colon as well as other tumors






44. Hereditary nephritis associated with nerve deafness and ocular disorders - mutation in gene for the a5 chain of type IV collagen






45. Aka acute disseminated langerhans cell histiocytosis - aggressive - usually fatal - kids hepatosplenomegaly - LAD - pancytopenia - pulmonary involvement - recurrent infections






46. Binucleated or multinucleated giant cell seen in Hodgkin dx






47. Nuclei arranged in horseshoe - shaped pattern about periphery of cell - characteristic of but not specific for granulomatous TB (as opposed to a foreign body giant cell that has scattered nuclei)






48. Vaginal epithelial cell with stippled appearance due to adherent coccobacilli






49. Clear cell renal tumor seen in kids






50. Deficient hexosaminidase A - GM2 ganglioside accumulation - especially in neurons - CNS degeneration - mental/motor deterioration - blindness - cherry red spot on macula - death by 4 years of age