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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Defective cilia - sinusitis - bronchiectasis - situs inversus - sometimes hearing loss and male sterility






2. Minute neutrophilic abscesses found within parakeratotic stratum corneum in psoriasis






3. Gene mutated in achondroplasia (most common form of dwarfism) - located at 4p16.3






4. Aka pituitary cachexia - generalized panhypopituitarism






5. Appears as multiple wart - like lesions resembling condyloma accuminatum






6. Aka neurofibromatosis - neurofibromas in skin - schwannomas of CN VIII - caf






7. Malignant lymphoma with features resembling inflammatory disorder - young men - Reed Sternburg cells






8. Binucleated or multinucleated giant cell seen in Hodgkin dx






9. Aka angiokeratoma corporis diffusum universal - deficient a::galactosidase A - accumulate ceramide trihexoside - skin lesions angiokeratomas - fever - burning pain in extremities - cardiovascular and cerebrovascular involvement - death as adult by re






10. Severe unconj hyperbilirubinemia due to deficient glucuronyl transferase






11. Lots of tumors - breast CA - soft tissue sarc - brain tumors - leukemias - has loss of p53 tumor suppressor gene






12. Associated with Wegener granulomatosis






13. Oncogenes that code for p21 proteins which are membrane signalers






14. Catastrophic adrenal insuff and vascular collapse - hemorrhagic necrosis of adrenal cortex






15. Subcutaneous fibrosis of dorsum of penis






16. Epithelial cells with eosinophilc granular cytoplasm seen in hashimoto






17. Parkinsonism with autonomic dysfunction and orthostatic hypotension






18. Hemihypertrophy - macroglossia - organomegaly - neonatal hypoglycemia - various embryonal tumors - deleted WT 2 gene






19. Autosomal dominant - numerous adenomatous polyps along with osteomas and soft tissue tumors






20. Aka infantile progressive spinal muscular atrophy - autosomal recessive - LMN disease - infants






21. Nystagmus - intention tremor - scanning speech - seen in MS






22. Osteophytes at DIP joints






23. Dysplastic cell seen in HPV






24. Aka superior sulcus tumor - seen in bronchogenic CA - often with Horner's






25. Aka polycystic ovary syndrome - young women - amenorrhea - infertility - obesity - hirsutism






26. Triad of ovarian fibroma - ascites - hydrothorax






27. Modest elevated serum unconj bilirubin - due to decreased uptake by liver cells and reduced activity of glucuronyl transferase






28. Seen in urine of patients with multiple myeloma - Ig light chain either k or l






29. Aka lentigo maligna - precursor to lentigo maligna melanoma






30. Deficient glucose -6- phosphatase - accumulation of glycogen in liver and kidney - hepatomegaly - hypoglycemia






31. Metastatic stomach CA to ovary






32. Aka pulseless dx - inflammation and stenosis of medium and large sized arteries - often aortic arch thus aortic arch syndrome






33. Intra::alveolar hemosiderin - laden macrophages caused by RBCs from capillary rupture 2* to pulmonary HTN






34. Aka mucocutaneous lymph node syndrome - acute self - limited - infants and young kids - acute necrotizing vasculitis of small and medium vessels - fever hemorrhagic edema of conjunctivae - lips and oral mucosa - and cervical LAD - can cause coronary






35. Deficient glucocerebrosidase - accumulation of glucocerebroside in cells of mononuclear phagocyte system 3 types ::






36. Acute promyelocytic leukemia PML gene on 15 and RARa on 17






37. B Thalassemia major






38. Mutation = paroxysmal nocturnal hemoglobinuria






39. Diffuse nodular diabetic glomerulosclerosis






40. Seen in Down synd - small white spots on periphery of iris






41. Associated with papillary thyroid CA






42. Occurs in SLE - small vegitations on either or both surfaces of valves






43. Hamartomatous polyps in colon and small intest - freckles on lips - hands - genitalia - higher incidence of adeno CA of colon and other malignancies - stomach - breast - ovaries






44. = MEN1






45. Autosomal recessive - hepatitis - accumulation of copper due to transport problem - low ceruloplasmin seen - kayser fleischer rings in eyes






46. Nuclei arranged in horseshoe - shaped pattern about periphery of cell - characteristic of but not specific for granulomatous TB (as opposed to a foreign body giant cell that has scattered nuclei)






47. Ring of copper deposited around iris seen in Wilson






48. Aka IgA nephropathy - deposition of IgA in mesangium - benign recurrent hematuria in kids following infection






49. Aka acute disseminated langerhans cell histiocytosis - aggressive - usually fatal - kids hepatosplenomegaly - LAD - pancytopenia - pulmonary involvement - recurrent infections






50. Unknown etiology - necrotizing granulomatous vasculitis of small to medium sized vessels of the respiratory tract - kidneys - and other organs - circulating C- ANCAs