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Test your basic knowledge |
USMLE Brs Pathology Vocab
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Subjects
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health-sciences
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usmle
Instructions:
Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Tumor suppressor mutated in Von Recklinhousen
Peutz Jeghers syndrome
NF1
Budd Chiari
Plummer dx
2. Small round eosinophilic masses found in dieing hepatocytes often containing chromatin remnants seen in viral hepatitis
Fanconi syndrome
Councilman body
Bouchard nodes
Wermer syndrome
3. Iron deficient anemia associated with upper::esophageal web
Plummer Vinson syndrome
Brushfield spots
Edwards syndrome
Kawasaki dx
4. Similar to paget breast - sometimes related to underlying adenoCA of sweat glands
Paget dx of vulva
Hashimoto thyroiditis
Berger dx
Wiskott Aldrich syndrome
5. Autosomal recessive - hepatitis - accumulation of copper due to transport problem - low ceruloplasmin seen - kayser fleischer rings in eyes
Von Gierke dx
Bernard Soulier dx
Clue cell
Wilson dx
6. Epithelial cells with eosinophilc granular cytoplasm seen in hashimoto
Heberden nodes
Hurthle cell
ANAs in SLE
Simmonds dx
7. Osteophytes at DIP joints
Kartagener syndrome
Heberden nodes
Plummer dx
GNAS1
8. Infectious disorder - caused postencephalitic parkinsonism
Huntington dx
Takayasu arteritis
McArdle syndrome
Von economo encephalitis
9. Single erythematous plaque on shaft of penis or scrotum
Bowen dx
8:14
Hunter syndrome
Starry sky appearance
10. At least 2 X and one Y - hypogonadism - tall - gynecomastia - low testosterone - high pituitary gonadotropins - infertility -
Pompe dx
Klinefelter syndrome
Hashimoto thyroiditis
Simmonds dx
11. Aka IgA nephropathy - deposition of IgA in mesangium - benign recurrent hematuria in kids following infection
Berger dx
Paget dx of breast
Starry sky appearance
Paget dx of bone
12. Aka trisomy 18 - mental retardation - prominent occiput - micrognathia (small jaw) - low::set ears - rocker::bottom feet - finger deformities - congenital heart dx
NF1
Edwards syndrome
ret
C ANCA
13. Pigmented iris hamartoma seen in neurofibromatosis
Sturge Weber syndrome
Birbeck granule
GNAS1
Lisch nodule
14. Paracentric inversion or translocation with 17 associated with papillary thyroid CA
Goodpasture syndrome
Letterer Siwe dx
Clue cell
Chromosome 10
15. Aka pulseless dx - inflammation and stenosis of medium and large sized arteries - often aortic arch thus aortic arch syndrome
Starry sky appearance
Hirano bodies
PIG A
Takayasu arteritis
16. Downward displacement of cerebellar tonsils and medulla through foramen magnum
Hartnup dx
Sheehan syndrome
Smudge cells
Arnold Chiari formation
17. Severe unconj hyperbilirubinemia due to deficient glucuronyl transferase
Von Hippel Lindau dx
Beriberi
Codman triangle
Crigler Najjar syndrome
18. Acute inflammatory demyelinating dx primarily involving peripheral nerves
Edwards syndrome
Guillain Barre syndrome
Plummer Vinson syndrome
Rotor syndrome
19. Asbestosis - yellow - brown - rod shaped body with clubbed ends - stain with Prussian blue
ANAs in SLE
Ferruginous body
Charcot Bouchard aneurysm
Paget dx of bone
20. Eczematoid lesion of nipple areola - large cells with clear 'halo like' area - invade epidermis - underlying ductal CA
Bcl2
Lisch nodule
Paget dx of breast
Wilson dx
21. Oncogenes that code for p21 proteins which are membrane signalers
Dubin Johnson syndrome
Whipple dx
Ras oncogenes
Aschoff body
22. Thrombotic occlusion of major hepatic veins - abnormal pain - jaundice - hepatomegaly - acites - liver failure - assoc with polycythemia vera - hepatocellular CA - and other common neoplasms - may occur as a complication of pregnancy
Hashimoto thyroiditis
N
Budd Chiari
Stein Leventhal syndrome
23. Renal tubular dysfunction - impaired reabsorption of glucose - amino acids - phosphate - and bicarb thus glycosuria - hyperphosphaturia - hypophosphatemia - aminoaciduria - systemic acidosis
Denys Drash syndrome
DiGeorge syndrome
Fanconi syndrome
Gaucher dx
24. Aka hereditary hemorrhagic telangectasia - telangectasias in skin and mucous membranes - epistaxis - GI bleeds
Klinefelter syndrome
Osler Weber Rendu syndrome
Chromosome 10
Brenner tumor
25. X linked - aka immunodeficiency with thrombocytopenia and eczema - total immunoglobulins often normal - recurrent infections
Gaucher dx
Wiskott Aldrich syndrome
Reidel thyroiditis
Hfe gene
26. Esophageal diverticulum just above upper esoph sphincter
Zenker diverticulum
Whipple dx
Wilson dx
Osler Weber Rendu syndrome
27. Associated with Wegener granulomatosis
Crigler Najjar syndrome
Alport syndrome
Beckwith Weidemann syndrome
C ANCA
28. Nuclei arranged in horseshoe - shaped pattern about periphery of cell - characteristic of but not specific for granulomatous TB (as opposed to a foreign body giant cell that has scattered nuclei)
Langhans giant cell
Paget dx of bone
Bowen dx
McCune Albright syndrome
29. Autoimmune thyroiditis - hyperthyroid - exophthalmos - increased in HLA DR3 and HLA B8 pos people
PIG A
Langhans giant cell
Graves dx
Call Exner bodies
30. Vasosmasm of small vessels - most often in fingers - seen with autoimmune dx like SLE - scleroderma and others (R in CREST) - recurrent vasospasm - always secondary to underlying disorder
Raynaud phenomenon
Burkitt lymphoma
McCune Albright syndrome
Hirano bodies
31. Unknown etiology - necrotizing granulomatous vasculitis of small to medium sized vessels of the respiratory tract - kidneys - and other organs - circulating C- ANCAs
Gardner syndrome
Dubin Johnson syndrome
Bernard Soulier dx
Wegener granulomatosis
32. Combination of hyperthyroidism - nodular goiter - absence of exophthalmos
HLA B27 antigen
Guillain Barre syndrome
McArdle syndrome
Plummer dx
33. Scheinker syndrome :: prion dx - fatal familial insomnia
Albers SCHonberg dx
Gerstmann Straussler
Graves dx
Gaucher dx
34. Manifestation of lymphplasmocytic lymphoma - B cell neoplasm
Wermer syndrome
Chromosome 10
Waldenstrom Macroglobulinemia
Budd Chiari
35. Aka osteopetrosis - marble bone dx - dense skeleton - failure of osteoclastic activity
Brenner tumor
Paget dx of bone
Albers SCHonberg dx
HER
36. Autosomal dominant - numerous adenomatous polyps along with osteomas and soft tissue tumors
Guillain Barre syndrome
Gardner syndrome
Hand Schuller Christian dx
Turner syndrome
37. Aka velocardiofacial syndrome and CATCH 22 syndrome - micro deletion of 22q11 - Cardiac abnormalities - Abnormal facies - T cell deficit due to thymic hypoplasia - Cleft palate - Hypocalcemia due to hypoparathyroidism - from poor development of 3rd a
Gilbert syndrome
Berger dx
Beckwith Weidemann syndrome
DiGeorge syndrome
38. Mucinous cell - characteristic of stomach CA met to ovary (krukenberg tumor)
Signet ring cell
Koilocyte
Kimmelsteil Wilson dx
ANAs in SLE
39. Associated with papillary thyroid CA
Raynaud phenomenon
Potter sequence
Waldenstrom Macroglobulinemia
ret PTC
40. Autosomal recessive - unusually large platelets - lack of 'GPIb IX V'
Smudge cells
Hashimoto thyroiditis
Alport syndrome
Bernard Soulier dx
41. Associated with breast alone (isn't one of these associated with prostate? Check)
Gardner syndrome
Huntington dx
BRCA2
Rouleaux formation
42. Non::neoplastic tumor like masses - fibrous replacement of resorbed bone
Heart failure cells
Brushfield spots
Lisch nodule
Brown tumor
43. Aka angiokeratoma corporis diffusum universal - deficient a::galactosidase A - accumulate ceramide trihexoside - skin lesions angiokeratomas - fever - burning pain in extremities - cardiovascular and cerebrovascular involvement - death as adult by re
Fabry dx
Niemann Pick dx
Churg Strauss syndrome
Shy Drager syndrome
44. = MEN2a
Raynaud disease
Sipple syndrome
Ewing sarcoma
Hartnup dx
45. Deficient fibrillin (constituent of microfibrils) - arachnodactyly - ectopia lentis - aortic aneurysm - mitral valve prolapsed
Codman triangle
Marfan syndrome
Whipple dx
Paget dx of bone
46. Seen in hyperacute rejection - = acute inflammation - fibrinoid necrosis of small vessels - and extensive thrombosis
9:22
HLA B27 antigen
Arthus reaction
Henoch Schonlein Purpura
47. Aka infantile progressive spinal muscular atrophy - autosomal recessive - LMN disease - infants
Btk gene
Werdnig Hoffman syndrome
FGFR3
Edwards syndrome
48. 45 XO - female hypogonadism - hypothyroid - short - webbed neck - 1* amenorrhea p52
Hfe gene
Turner syndrome
Kimmelstiel Wilson nodules
Whipple dx
49. Gene product facilitates apoptosis
GNAS1
Hashimoto thyroiditis
Bax
Charcot Bouchard aneurysm
50. Seen in CLL - leukemic B- cells that are fragile
Smudge cells
Paget dx of breast
Li Fraumeni syndrome
Berger dx
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