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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Minute neutrophilic abscesses found within parakeratotic stratum corneum in psoriasis






2. Mucinous cell - characteristic of stomach CA met to ovary (krukenberg tumor)






3. Oncogenes that code for p21 proteins which are membrane signalers






4. Autosomal dominant - fatal - progressive degeneration of striatum and frontal cortex with neuronal depletion and gliosis






5. 2/neu :: oncogene (aka c - erbB2) - in breast cancer = poor prognosis






6. Development of large pituitary adenomas following bilat adrenalectomy






7. Aka polycystic ovary syndrome - young women - amenorrhea - infertility - obesity - hirsutism






8. Small round blue cell tumor of bone - long bones - kids - 11:22 transloc






9. Pigmented iris hamartoma seen in neurofibromatosis






10. Downward displacement of cerebellar tonsils and medulla through foramen magnum






11. Seen in hyperacute rejection - = acute inflammation - fibrinoid necrosis of small vessels - and extensive thrombosis






12. Also seen in urine of MM - stacks of RBCs - will have high ESR






13. Combination of hyperthyroidism - nodular goiter - absence of exophthalmos






14. Non::neoplastic tumor like masses - fibrous replacement of resorbed bone






15. Deficient hypoxanthine::guanine phosphoribosyltransferase (HGPRT) - low purine metabolism - high uric acid - thus gout - mental retardation - choreoathetosis - spasticity - self mutilation - aggressiveness






16. Chromosome 19 - allele common in alzheimers






17. Autosomal recessive - neutropenia - albinism - cranial and peripheral neuropathy - tendency to develop repeated infections - abnormal WBCs (abnormal mictotubul formation and large cytoplasmic granules = lysosomes)






18. Esophageal diverticulum just above upper esoph sphincter






19. Small follicles filled with eosinophilic secretion - diagnostic feature of granulose cell tumor






20. Seen in papillary thyroid CA






21. Manifestation of lymphplasmocytic lymphoma - B cell neoplasm






22. Philadelphia chromosome - CML bcr abl fusion c - abl on 9 - bcr on 22






23. Similar to Dubin Johnson with no black liver






24. Hemihypertrophy - macroglossia - organomegaly - neonatal hypoglycemia - various embryonal tumors - deleted WT 2 gene






25. Vasosmasm of small vessels - most often in fingers - seen with autoimmune dx like SLE - scleroderma and others (R in CREST) - recurrent vasospasm - always secondary to underlying disorder






26. Lots of tumors - breast CA - soft tissue sarc - brain tumors - leukemias - has loss of p53 tumor suppressor gene






27. Defective cilia - sinusitis - bronchiectasis - situs inversus - sometimes hearing loss and male sterility






28. Tumor suppressor mutated in breast and ovary






29. Aka trisomy 18 - mental retardation - prominent occiput - micrognathia (small jaw) - low::set ears - rocker::bottom feet - finger deformities - congenital heart dx






30. Abnormal WT 1 gene - intersexual disorders - nephropathy - wilms tumor






31. Radiologic appearance of periostium in bone tumors






32. Small round eosinophilic masses found in dieing hepatocytes often containing chromatin remnants seen in viral hepatitis






33. Autosomal dominant - numerous adenomatous polyps along with osteomas and soft tissue tumors






34. Modest elevated serum unconj bilirubin - due to decreased uptake by liver cells and reduced activity of glucuronyl transferase






35. Subcutaneous fibrosis of dorsum of penis






36. Aka mucocutaneous lymph node syndrome - acute self - limited - infants and young kids - acute necrotizing vasculitis of small and medium vessels - fever hemorrhagic edema of conjunctivae - lips and oral mucosa - and cervical LAD - can cause coronary






37. Ovarian tumor resembling bladder transitional epith






38. DsDNA antibodies and Sm Smith antigen = highly specific for SLE






39. Single erythematous plaque on shaft of penis or scrotum






40. Associated with breast alone (isn't one of these associated with prostate? Check)






41. Follicular lymphoma IG heavy chain on 14 - bcl -2 oncogene on 18






42. Aka angiokeratoma corporis diffusum universal - deficient a::galactosidase A - accumulate ceramide trihexoside - skin lesions angiokeratomas - fever - burning pain in extremities - cardiovascular and cerebrovascular involvement - death as adult by re






43. Intra::alveolar hemosiderin - laden macrophages caused by RBCs from capillary rupture 2* to pulmonary HTN






44. X linked - aka immunodeficiency with thrombocytopenia and eczema - total immunoglobulins often normal - recurrent infections






45. Mutation = paroxysmal nocturnal hemoglobinuria






46. Iron deficient anemia associated with upper::esophageal web






47. Autosomal recessive - unusually large platelets - lack of 'GPIb IX V'






48. Osteophytes at DIP joints






49. Malignant lymphoma with features resembling inflammatory disorder - young men - Reed Sternburg cells






50. = MEN2a