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Test your basic knowledge |
USMLE Brs Pathology Vocab
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Subjects
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health-sciences
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usmle
Instructions:
Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Vaginal epithelial cell with stippled appearance due to adherent coccobacilli
Clue cell
Hartnup dx
Dry beriberi
p53
2. 2/neu :: oncogene (aka c - erbB2) - in breast cancer = poor prognosis
Von Recklinhousen dx
HER
Graves dx
Wiskott Aldrich syndrome
3. Gene product inhibits apoptosis
Cri du chat syndrome
Conn syndrome
Aschoff body
Bcl2
4. Triad of ovarian fibroma - ascites - hydrothorax
Churg Strauss syndrome
Starry sky appearance
Wilms tumor
Meigs syndrome
5. Aka hereditary hemorrhagic telangectasia - telangectasias in skin and mucous membranes - epistaxis - GI bleeds
Osler Weber Rendu syndrome
Aschoff body
Ras oncogenes
Hand Schuller Christian dx
6. Similar to Dubin Johnson with no black liver
NF1
Hirschsprung dx
Rotor syndrome
Hand Schuller Christian dx
7. Deficient hypoxanthine::guanine phosphoribosyltransferase (HGPRT) - low purine metabolism - high uric acid - thus gout - mental retardation - choreoathetosis - spasticity - self mutilation - aggressiveness
Starry sky appearance
Pancoast tumor
Bax
Lesch Nyhan syndrome
8. Defective in x- linked brutons agammaglobulinemia - B- cell tyrosine kinase
Btk gene
Bax
Goodpasture syndrome
Hfe gene
9. Aka congenital megacolon - dilation of colon due to absence of ganglion cells
Hirschsprung dx
Lesch Nyhan syndrome
Burkitt lymphoma
Pompe dx
10. Occurs in SLE - small vegitations on either or both surfaces of valves
Wilson dx
Hurthle cell
Bowenoid papulosis
Libman Sacks endocarditis
11. Deficient sphingomyelinase - accumulation of sphingomyelin in phagocytes - foamy histiocytes in liver - spleen - lymph nodes - skin - hepatosplenomegaly - anemia fever - occasional neuro degeneration - half have cherry red spot macula
Langhans giant cell
Patau syndrome
Niemann Pick dx
Charcot Bouchard aneurysm
12. Follicular lymphoma IG heavy chain on 14 - bcl -2 oncogene on 18
Libman Sacks endocarditis
Bernard Soulier dx
Berger dx
14:18
13. Lots of tumors - breast CA - soft tissue sarc - brain tumors - leukemias - has loss of p53 tumor suppressor gene
Councilman body
Li Fraumeni syndrome
Whipple triad
Takayasu arteritis
14. 45 XO - female hypogonadism - hypothyroid - short - webbed neck - 1* amenorrhea p52
Turner syndrome
Reye syndrome
Orphan annie nuclei
Mediterranean anemia or Cooley Anemia
15. Aka acute disseminated langerhans cell histiocytosis - aggressive - usually fatal - kids hepatosplenomegaly - LAD - pancytopenia - pulmonary involvement - recurrent infections
Brown tumor
Letterer Siwe dx
Goodpasture syndrome
Beckwith Weidemann syndrome
16. Autoimmune thyroiditis - hyperthyroid - exophthalmos - increased in HLA DR3 and HLA B8 pos people
Whipple dx
PIG A
FGFR3
Graves dx
17. Acute inflammatory demyelinating dx primarily involving peripheral nerves
Von Gierke dx
Waterhouse Friderichsen syndrome
Guillain Barre syndrome
FGFR3
18. Polyostotic fibrous dysplasia - precocious puberty - caf
McCune Albright syndrome
Lisch nodule
McArdle syndrome
Sipple syndrome
19. Aspirin toxicity seen in kids after acute febrile viral dx - microvesicular fatty change in liver and encephalopathy
Hartnup dx
Turner syndrome
Brenner tumor
Reye syndrome
20. Small follicles filled with eosinophilic secretion - diagnostic feature of granulose cell tumor
Von Gierke dx
Call Exner bodies
Budd Chiari
Heart failure cells
21. Asbestosis - yellow - brown - rod shaped body with clubbed ends - stain with Prussian blue
McCune Albright syndrome
Li Fraumeni syndrome
Fabry dx
Ferruginous body
22. Superclavicular lymph node identifying metastatic stomach CA
Goodpasture syndrome
Heart failure cells
Virchow node
Burkitt lymphoma
23. Combination of hyperthyroidism - nodular goiter - absence of exophthalmos
Birbeck granule
Budd Chiari
11:22
Plummer dx
24. Pigmented iris hamartoma seen in neurofibromatosis
Gerstmann Straussler
Reiter syndrome
Lisch nodule
Crigler Najjar syndrome
25. Infectious disorder - caused postencephalitic parkinsonism
Beckwith Weidemann syndrome
Von economo encephalitis
Ewing sarcoma
Dubin Johnson syndrome
26. Autosomal dominant - numerous adenomatous polyps along with osteomas and soft tissue tumors
Li Fraumeni syndrome
Gardner syndrome
Wilson dx
Osler Weber Rendu syndrome
27. Nuclei arranged in horseshoe - shaped pattern about periphery of cell - characteristic of but not specific for granulomatous TB (as opposed to a foreign body giant cell that has scattered nuclei)
Budd Chiari
Klinefelter syndrome
McArdle syndrome
Langhans giant cell
28. Autosomal dominant - fatal - progressive degeneration of striatum and frontal cortex with neuronal depletion and gliosis
Paget dx of vulva
Smudge cells
Huntington dx
Alport syndrome
29. Aka osteopetrosis - marble bone dx - dense skeleton - failure of osteoclastic activity
Albers SCHonberg dx
Sturge Weber syndrome
Reye syndrome
Burkitt lymphoma
30. Binucleated or multinucleated giant cell seen in Hodgkin dx
Hand Schuller Christian dx
Gilbert syndrome
Reed Sternburg cell
Reiter syndrome
31. Adenomatous polyps with tumors of CNS
Turcot syndrome
Addison disease
Potter sequence
Peutz Jeghers syndrome
32. Oncogenes that code for p21 proteins which are membrane signalers
Osler Weber Rendu syndrome
8:14
Ras oncogenes
Starry sky appearance
33. Impaired tubular reabsorption of tryptophan - pellagra::like manifestations
Hartnup dx
Plummer Vinson syndrome
Hfe gene
Osler Weber Rendu syndrome
34. Protooncogene mutated in medulary thyroid CA (MENII)
Goodpasture syndrome
Bouchard nodes
ret
Mediterranean anemia or Cooley Anemia
35. Malignant lymphoma with features resembling inflammatory disorder - young men - Reed Sternburg cells
Lambert Eaton syndrome
8:14
Hodgkin dx
Meigs syndrome
36. Seen in urine of patients with multiple myeloma - Ig light chain either k or l
Bense Jones protein
Potter sequence
Ras oncogenes
Langhans giant cell
37. Peripheral neuropathy - atrophy of muscles - wet - high output cardiac failure - DCM - AV shunting - hypervolemia
Hurthle cell
Paget dx of vulva
Dry beriberi
Clue cell
38. Deficient a1 -4 glucosidase - accumulation of glycogen in liver - heart - skeletal muscle - cardiomegaly - muscle hypotonia - spelnomegaly - intractable hypoglycemia - death from cardiorespiratory failure before age 3
Rotor syndrome
Pompe dx
Wegener granulomatosis
Angelman syndrome
39. Aka pituitary cachexia - generalized panhypopituitarism
Letterer Siwe dx
Simmonds dx
Krukenberg tumor
Wilson dx
40. Deficient glucose -6- phosphatase - accumulation of glycogen in liver and kidney - hepatomegaly - hypoglycemia
Binswanger dx
Simmonds dx
Von Gierke dx
N
41. X linked - absence of plasma cells and serum immunoglobulins - cell mediated immunity still ok - no germinal centers - recurrent bacterial infections - resistances to fungal and viral still - btk gene defect
Denys Drash syndrome
Brutons Agammaglobulinemia
Mediterranean anemia or Cooley Anemia
Still disease
42. Parkinsonism with autonomic dysfunction and orthostatic hypotension
ret PTC
Gardner syndrome
Stein Leventhal syndrome
Shy Drager syndrome
43. Aka pulseless dx - inflammation and stenosis of medium and large sized arteries - often aortic arch thus aortic arch syndrome
Takayasu arteritis
Goodpasture syndrome
Reye syndrome
Wilms tumor
44. Aneurysm at small artery bifurcations
Gardner syndrome
Alport syndrome
Charcot Bouchard aneurysm
Wilson dx
45. Deficient hexosaminidase A - GM2 ganglioside accumulation - especially in neurons - CNS degeneration - mental/motor deterioration - blindness - cherry red spot on macula - death by 4 years of age
Tay Sachs dx
Chromosome 10
Reye syndrome
Birbeck granule
46. Associated with 90% cases of ankylosing spondylitis - common in rheumatoid arthritis
Potter sequence
Donovan bodies
Hashimoto thyroiditis
HLA B27 antigen
47. Metastatic stomach CA to ovary
Krukenberg tumor
McArdle syndrome
Hand Schuller Christian dx
Langhans giant cell
48. Transloc seen in ewing sarcoma
Paget dx of vulva
Takayasu arteritis
11:22
Reinke crystal
49. Similar to paget breast - sometimes related to underlying adenoCA of sweat glands
Starry sky appearance
Paget dx of vulva
Cri du chat syndrome
Felty syndrome
50. X linked - aka immunodeficiency with thrombocytopenia and eczema - total immunoglobulins often normal - recurrent infections
Langhans giant cell
Birbeck granule
Wiskott Aldrich syndrome
Budd Chiari
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