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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Osteophytes at PIP joints






2. Tumor suppressor mutated in wilms tumor






3. Asbestosis - yellow - brown - rod shaped body with clubbed ends - stain with Prussian blue






4. Gene product facilitates apoptosis






5. Follicular lymphoma IG heavy chain on 14 - bcl -2 oncogene on 18






6. Different in that it is the primary disorder - recurrent vasospasm of small arteries and venules - pallor - cyanosis - fingers and toes - young healthy women






7. Peripheral neuropathy - atrophy of muscles - wet - high output cardiac failure - DCM - AV shunting - hypervolemia






8. Burkitts c::myc is on 8 - IG heavy chain is on 14






9. Gene product inhibits apoptosis






10. Aka chronic progressive histiocytosis - not as bad as Letterer Siwe






11. Tumor suppressor common in familial polyposis coli and adenoCA of colon as well as other tumors






12. Seen in hyperacute rejection - = acute inflammation - fibrinoid necrosis of small vessels - and extensive thrombosis






13. Hereditary nephritis associated with nerve deafness and ocular disorders - mutation in gene for the a5 chain of type IV collagen






14. Aka velocardiofacial syndrome and CATCH 22 syndrome - micro deletion of 22q11 - Cardiac abnormalities - Abnormal facies - T cell deficit due to thymic hypoplasia - Cleft palate - Hypocalcemia due to hypoparathyroidism - from poor development of 3rd a






15. Acute inflammatory demyelinating dx primarily involving peripheral nerves






16. Retinoblastoma on chromosome 13






17. = MEN1






18. Osteophytes at DIP joints






19. Variant of rheumatoid arthritis - aka juvenile rheumatoid arthritis






20. Aggressive B- cell lymphoma - EBV - starry sky appearance - c myc






21. Autosomal dominant - numerous adenomatous polyps along with osteomas and soft tissue tumors






22. Aka subcortical leukoencephalopathy - assoc with HTN - multiple lacunar infarcts and progressive demyelination in subcortical area






23. Metastatic stomach CA to ovary






24. Iron deficient anemia associated with upper::esophageal web






25. Associated with papillary thyroid CA






26. Deficient glucocerebrosidase - accumulation of glucocerebroside in cells of mononuclear phagocyte system 3 types ::






27. Aka IgA nephropathy - deposition of IgA in mesangium - benign recurrent hematuria in kids following infection






28. Radiologic appearance of periostium in bone tumors






29. Small round eosinophilic masses found in dieing hepatocytes often containing chromatin remnants seen in viral hepatitis






30. Aka mucocutaneous lymph node syndrome - acute self - limited - infants and young kids - acute necrotizing vasculitis of small and medium vessels - fever hemorrhagic edema of conjunctivae - lips and oral mucosa - and cervical LAD - can cause coronary






31. Defective in x- linked brutons agammaglobulinemia - B- cell tyrosine kinase






32. Seen in granuloma inguinale - multiple organisms filling large histiocytes






33. Appears as multiple wart - like lesions resembling condyloma accuminatum






34. Aka hereditary hemorrhagic telangectasia - telangectasias in skin and mucous membranes - epistaxis - GI bleeds






35. Gene mutated in achondroplasia (most common form of dwarfism) - located at 4p16.3






36. Deficient a1 -4 glucosidase - accumulation of glycogen in liver - heart - skeletal muscle - cardiomegaly - muscle hypotonia - spelnomegaly - intractable hypoglycemia - death from cardiorespiratory failure before age 3






37. Nuclei arranged in horseshoe - shaped pattern about periphery of cell - characteristic of but not specific for granulomatous TB (as opposed to a foreign body giant cell that has scattered nuclei)






38. Acute promyelocytic leukemia PML gene on 15 and RARa on 17






39. Aspirin toxicity seen in kids after acute febrile viral dx - microvesicular fatty change in liver and encephalopathy






40. Eczematoid lesion of nipple areola - large cells with clear 'halo like' area - invade epidermis - underlying ductal CA






41. Aka infantile progressive spinal muscular atrophy - autosomal recessive - LMN disease - infants






42. Scheinker syndrome :: prion dx - fatal familial insomnia






43. Tennis racket shaped cytoplasmic inclusion seen in langerhans cells (so also seen in langerhan cell histiocytosis)






44. Thrombotic occlusion of major hepatic veins - abnormal pain - jaundice - hepatomegaly - acites - liver failure - assoc with polycythemia vera - hepatocellular CA - and other common neoplasms - may occur as a complication of pregnancy






45. Pigmented iris hamartoma seen in neurofibromatosis






46. X linked - absence of plasma cells and serum immunoglobulins - cell mediated immunity still ok - no germinal centers - recurrent bacterial infections - resistances to fungal and viral still - btk gene defect






47. Aka trisomy 13 - mental retardation - microcephaly - micropthalmia - brain abnormalities - cleft lip/palate - polydactyly - rockerbottom feet - congenital heart dx






48. Oncogenes that code for p21 proteins which are membrane signalers






49. Severe unconj hyperbilirubinemia due to deficient glucuronyl transferase






50. Variant of rheumatoid arthritis - splenmegally - neutropenia - RA