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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Eosinophilic intracytoplasmic inclusions in hippocampus and purkinje cells seen in rabies infection






2. Associated with Wegener granulomatosis






3. Pituitary insufficiency post - partum - low TSH ACTH






4. Nuclei arranged in horseshoe - shaped pattern about periphery of cell - characteristic of but not specific for granulomatous TB (as opposed to a foreign body giant cell that has scattered nuclei)






5. Seen in CLL - leukemic B- cells that are fragile






6. Aka mucocutaneous lymph node syndrome - acute self - limited - infants and young kids - acute necrotizing vasculitis of small and medium vessels - fever hemorrhagic edema of conjunctivae - lips and oral mucosa - and cervical LAD - can cause coronary






7. Asbestosis - yellow - brown - rod shaped body with clubbed ends - stain with Prussian blue






8. Hereditary nephritis associated with nerve deafness and ocular disorders - mutation in gene for the a5 chain of type IV collagen






9. Deficient glucose -6- phosphatase - accumulation of glycogen in liver and kidney - hepatomegaly - hypoglycemia






10. Similar to paget breast - sometimes related to underlying adenoCA of sweat glands






11. Thyroid replacement by fibrous tissue - unkown origin - mimics






12. Protooncogene mutated in medulary thyroid CA (MENII)






13. Hemihypertrophy - macroglossia - organomegaly - neonatal hypoglycemia - various embryonal tumors - deleted WT 2 gene






14. Seen in papillary thyroid CA






15. Combination of hyperthyroidism - nodular goiter - absence of exophthalmos






16. Aka velocardiofacial syndrome and CATCH 22 syndrome - micro deletion of 22q11 - Cardiac abnormalities - Abnormal facies - T cell deficit due to thymic hypoplasia - Cleft palate - Hypocalcemia due to hypoparathyroidism - from poor development of 3rd a






17. Gene product facilitates apoptosis






18. Thrombotic occlusion of major hepatic veins - abnormal pain - jaundice - hepatomegaly - acites - liver failure - assoc with polycythemia vera - hepatocellular CA - and other common neoplasms - may occur as a complication of pregnancy






19. Seen in Down synd - small white spots on periphery of iris






20. Primary adrenal failure






21. Oligohydramnios causes fetus to be smashed






22. Hemangioblastoma or cavernous hemangioma of cerebellum - brainstem or retina - adenomas - cysts in liver - kidney - pancreas - and other organs - increased renal cell CA - gene = short arm of chromosome 3






23. Adenomatous polyps with tumors of CNS






24. Seen in urine of patients with multiple myeloma - Ig light chain either k or l






25. Transloc seen in ewing sarcoma






26. Vasosmasm of small vessels - most often in fingers - seen with autoimmune dx like SLE - scleroderma and others (R in CREST) - recurrent vasospasm - always secondary to underlying disorder






27. Deficient muscle phosphorylase - glycogen in skeletal muscle - cramps with exertion






28. Non::neoplastic tumor like masses - fibrous replacement of resorbed bone






29. Follicular lymphoma IG heavy chain on 14 - bcl -2 oncogene on 18






30. Seen in hyperacute rejection - = acute inflammation - fibrinoid necrosis of small vessels - and extensive thrombosis






31. Mutation here causes pseudohypoparathyroidism






32. Aka allergic granulomatous angiitis - necrotizing vasculitis - variant of polyarteritis nodosa - involves pulmonary vasculature - peripheral eosinophilia - and asthma






33. 5p chromosome deletion - severe mental retardation - microcephaly - catlike cry - low birth weight - round face - hypertelorism (wide eyes)






34. Aka trisomy 13 - mental retardation - microcephaly - micropthalmia - brain abnormalities - cleft lip/palate - polydactyly - rockerbottom feet - congenital heart dx






35. Aneurysm at small artery bifurcations






36. Variant of rheumatoid arthritis - aka juvenile rheumatoid arthritis






37. Autosomal recessive - unusually large platelets - lack of 'GPIb IX V'






38. Single erythematous plaque on shaft of penis or scrotum






39. Autosomal recessive - conj hyperbilirubinemia - defect in bili transport - black color to liver






40. Ring of copper deposited around iris seen in Wilson






41. Aggressive B- cell lymphoma - EBV - starry sky appearance - c myc






42. Intra::alveolar hemosiderin - laden macrophages caused by RBCs from capillary rupture 2* to pulmonary HTN






43. Port wine stain on face - ipsilateral glaucoma - vascular lesions of ocular choroidal tissue - extensive hemangiomatous involvement of meninges






44. Tumor suppressor mutated in breast and ovary






45. Autoimmune thyroiditis - hyperthyroid - exophthalmos - increased in HLA DR3 and HLA B8 pos people






46. Vaginal epithelial cell with stippled appearance due to adherent coccobacilli






47. Chromosome 19 - allele common in alzheimers






48. Deficient fibrillin (constituent of microfibrils) - arachnodactyly - ectopia lentis - aortic aneurysm - mitral valve prolapsed






49. Abnormal WT 1 gene - intersexual disorders - nephropathy - wilms tumor






50. Paraneoplastic synd looks like myasthenia gravis - often small cell lung CA