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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Aka osteitis deformans - increased osteoclastic and osteoblastic activity






2. Follicular lymphoma IG heavy chain on 14 - bcl -2 oncogene on 18






3. Aka thromboangiitis obliterans - acute inflame of small and med arteries of extremities - extending to adjacent veins and nerves - young jewish men - painful ischemic dx - worse with smoking






4. Deficient glucose -6- phosphatase - accumulation of glycogen in liver and kidney - hepatomegaly - hypoglycemia






5. 45 XO - female hypogonadism - hypothyroid - short - webbed neck - 1* amenorrhea p52






6. Aka chronic progressive histiocytosis - not as bad as Letterer Siwe






7. Tumor suppressor mutated in Von Recklinhousen






8. Associated with Wegener granulomatosis






9. Burkitts c::myc is on 8 - IG heavy chain is on 14






10. Abnormal WT 1 gene - intersexual disorders - nephropathy - wilms tumor






11. Sphingomyelin containing phagocytes seen in Niemman::Pick dx in liver - spleen - lymph nodes and skin






12. Retinoblastoma on chromosome 13






13. Deficient muscle phosphorylase - glycogen in skeletal muscle - cramps with exertion






14. Aka lentigo maligna - precursor to lentigo maligna melanoma






15. X linked - absence of plasma cells and serum immunoglobulins - cell mediated immunity still ok - no germinal centers - recurrent bacterial infections - resistances to fungal and viral still - btk gene defect






16. Peripheral neuropathy - atrophy of muscles - wet - high output cardiac failure - DCM - AV shunting - hypervolemia






17. Aka angiokeratoma corporis diffusum universal - deficient a::galactosidase A - accumulate ceramide trihexoside - skin lesions angiokeratomas - fever - burning pain in extremities - cardiovascular and cerebrovascular involvement - death as adult by re






18. Seen in CLL - leukemic B- cells that are fragile






19. Seen in papillary thyroid CA






20. Unknown etiology - necrotizing granulomatous vasculitis of small to medium sized vessels of the respiratory tract - kidneys - and other organs - circulating C- ANCAs






21. Hereditary nonpolyposis colon cancer - DNA repair genes messed up






22. Aka velocardiofacial syndrome and CATCH 22 syndrome - micro deletion of 22q11 - Cardiac abnormalities - Abnormal facies - T cell deficit due to thymic hypoplasia - Cleft palate - Hypocalcemia due to hypoparathyroidism - from poor development of 3rd a






23. Deficient sphingomyelinase - accumulation of sphingomyelin in phagocytes - foamy histiocytes in liver - spleen - lymph nodes - skin - hepatosplenomegaly - anemia fever - occasional neuro degeneration - half have cherry red spot macula






24. Parkinsonism with autonomic dysfunction and orthostatic hypotension






25. Protooncogene mutated in medulary thyroid CA (MENII)






26. Superclavicular lymph node identifying metastatic stomach CA






27. At least 2 X and one Y - hypogonadism - tall - gynecomastia - low testosterone - high pituitary gonadotropins - infertility -






28. Aka polycystic ovary syndrome - young women - amenorrhea - infertility - obesity - hirsutism






29. Scheinker syndrome :: prion dx - fatal familial insomnia






30. Gene product facilitates apoptosis - decreases bcl::2 and increases Bax






31. Hemangioblastoma or cavernous hemangioma of cerebellum - brainstem or retina - adenomas - cysts in liver - kidney - pancreas - and other organs - increased renal cell CA - gene = short arm of chromosome 3






32. DsDNA antibodies and Sm Smith antigen = highly specific for SLE






33. Manifestation of lymphplasmocytic lymphoma - B cell neoplasm






34. Chromosome 19 - allele common in alzheimers






35. Diffuse nodular diabetic glomerulosclerosis






36. Osteophytes at PIP joints






37. Primary aldosteronism






38. Metastatic stomach CA to ovary






39. Philadelphia chromosome - CML bcr abl fusion c - abl on 9 - bcr on 22






40. Area of focal interstitial myocardial inflammation characterized by fragmented collagen and fibrinoid material - by large cells (Anitschkow myocytes) and occasional multinucleated giant cells (Aschoff cells)






41. Deficient debranching enzyme amylo -1 -6- glucosidase - glycogen in liver - heart - skeletal muscle - stunted growth - hepatomegaly - hypoglycemia






42. Autoimmune thyroiditis - hyperthyroid - exophthalmos - increased in HLA DR3 and HLA B8 pos people






43. Downward displacement of cerebellar tonsils and medulla through foramen magnum






44. Aka trisomy 13 - mental retardation - microcephaly - micropthalmia - brain abnormalities - cleft lip/palate - polydactyly - rockerbottom feet - congenital heart dx






45. Intra::alveolar hemosiderin - laden macrophages caused by RBCs from capillary rupture 2* to pulmonary HTN






46. Aka osteopetrosis - marble bone dx - dense skeleton - failure of osteoclastic activity






47. Hemorrhagic urticaria of extensor surgaces of arms - legs - and buttocks - with fever - arthralgias - and GI renal involvement similar to IgA nephropathy - associated with URIs






48. Intracytoplasmic proximal dentritic eosinophilic inclusions consisting of actin seen in Alzheimers






49. Intracytoplasmic inclusions seen in leydig cell tumors p283






50. Variant of rheumatoid arthritis - splenmegally - neutropenia - RA