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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Associated with 90% cases of ankylosing spondylitis - common in rheumatoid arthritis






2. Peripheral neuropathy - atrophy of muscles - wet - high output cardiac failure - DCM - AV shunting - hypervolemia






3. Hamartomatous polyps in colon and small intest - freckles on lips - hands - genitalia - higher incidence of adeno CA of colon and other malignancies - stomach - breast - ovaries






4. Pituitary insufficiency post - partum - low TSH ACTH






5. Primary adrenal failure






6. Acute promyelocytic leukemia PML gene on 15 and RARa on 17






7. Subcutaneous fibrosis of dorsum of penis






8. Intracytoplasmic inclusions seen in leydig cell tumors p283






9. Aka pituitary cachexia - generalized panhypopituitarism






10. Epithelial cells with eosinophilc granular cytoplasm seen in hashimoto






11. Lots of tumors - breast CA - soft tissue sarc - brain tumors - leukemias - has loss of p53 tumor suppressor gene






12. Radiologic appearance of periostium in bone tumors






13. Seen in insulinoma - episodic hyperinsulinemia and hypoglycemia - CNS dysfunction - reversal of CNS probs with administration of glucose






14. Sphingomyelin containing phagocytes seen in Niemman::Pick dx in liver - spleen - lymph nodes and skin






15. Seen in hyperacute rejection - = acute inflammation - fibrinoid necrosis of small vessels - and extensive thrombosis






16. Similar to paget breast - sometimes related to underlying adenoCA of sweat glands






17. Autosomal dominant - fatal - progressive degeneration of striatum and frontal cortex with neuronal depletion and gliosis






18. Gene product facilitates apoptosis






19. X linked - aka immunodeficiency with thrombocytopenia and eczema - total immunoglobulins often normal - recurrent infections






20. Aka angiokeratoma corporis diffusum universal - deficient a::galactosidase A - accumulate ceramide trihexoside - skin lesions angiokeratomas - fever - burning pain in extremities - cardiovascular and cerebrovascular involvement - death as adult by re






21. Chromosome 19 - allele common in alzheimers






22. Defective cilia - sinusitis - bronchiectasis - situs inversus - sometimes hearing loss and male sterility






23. Modest elevated serum unconj bilirubin - due to decreased uptake by liver cells and reduced activity of glucuronyl transferase






24. Deficient glucose -6- phosphatase - accumulation of glycogen in liver and kidney - hepatomegaly - hypoglycemia






25. Deficient muscle phosphorylase - glycogen in skeletal muscle - cramps with exertion






26. Metastatic stomach CA to ovary






27. Variant of rheumatoid arthritis - aka juvenile rheumatoid arthritis






28. Intra::alveolar hemosiderin - laden macrophages caused by RBCs from capillary rupture 2* to pulmonary HTN






29. On lymph node biopsy - seen with Burkitt lymphoma






30. Aka thromboangiitis obliterans - acute inflame of small and med arteries of extremities - extending to adjacent veins and nerves - young jewish men - painful ischemic dx - worse with smoking






31. Triad of ovarian fibroma - ascites - hydrothorax






32. Oncogenes that code for p21 proteins which are membrane signalers






33. Urethritis - conjunctivitis - arthritis - associated with venereal or intestinal infection






34. Aka subcortical leukoencephalopathy - assoc with HTN - multiple lacunar infarcts and progressive demyelination in subcortical area






35. Gene product facilitates apoptosis - decreases bcl::2 and increases Bax






36. Primary aldosteronism






37. Aka antiglomerular basement membrane dx - antibodies against alveolar and glomerular basement membranes - linear immunoflorescence






38. Adenomatous polyps with tumors of CNS






39. Autosomal recessive - conj hyperbilirubinemia - defect in bili transport - black color to liver






40. Hemangioblastoma or cavernous hemangioma of cerebellum - brainstem or retina - adenomas - cysts in liver - kidney - pancreas - and other organs - increased renal cell CA - gene = short arm of chromosome 3






41. Deficient debranching enzyme amylo -1 -6- glucosidase - glycogen in liver - heart - skeletal muscle - stunted growth - hepatomegaly - hypoglycemia






42. Binucleated or multinucleated giant cell seen in Hodgkin dx






43. Aka trisomy 13 - mental retardation - microcephaly - micropthalmia - brain abnormalities - cleft lip/palate - polydactyly - rockerbottom feet - congenital heart dx






44. Non::neoplastic tumor like masses - fibrous replacement of resorbed bone






45. Clear cell renal tumor seen in kids






46. Aka chronic progressive histiocytosis - not as bad as Letterer Siwe






47. Deficient hexosaminidase A - GM2 ganglioside accumulation - especially in neurons - CNS degeneration - mental/motor deterioration - blindness - cherry red spot on macula - death by 4 years of age






48. Mucopolysaccharidosis - deficient a L iduronidase - accumulations of heparin sulfate and dermatan sulfate in heart - brain - liver - and other organs - progressive - hepatosplenomagaly - dwarfism - gargoyle - like facies - stubby fingers - corneal cl






49. Scheinker syndrome :: prion dx - fatal familial insomnia






50. Nystagmus - intention tremor - scanning speech - seen in MS