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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Urethritis - conjunctivitis - arthritis - associated with venereal or intestinal infection






2. Vasosmasm of small vessels - most often in fingers - seen with autoimmune dx like SLE - scleroderma and others (R in CREST) - recurrent vasospasm - always secondary to underlying disorder






3. X linked - absence of plasma cells and serum immunoglobulins - cell mediated immunity still ok - no germinal centers - recurrent bacterial infections - resistances to fungal and viral still - btk gene defect






4. Port wine stain on face - ipsilateral glaucoma - vascular lesions of ocular choroidal tissue - extensive hemangiomatous involvement of meninges






5. On lymph node biopsy - seen with Burkitt lymphoma






6. Philadelphia chromosome - CML bcr abl fusion c - abl on 9 - bcr on 22






7. Renal tubular dysfunction - impaired reabsorption of glucose - amino acids - phosphate - and bicarb thus glycosuria - hyperphosphaturia - hypophosphatemia - aminoaciduria - systemic acidosis






8. Clear cell renal tumor seen in kids






9. Unknown etiology - necrotizing granulomatous vasculitis of small to medium sized vessels of the respiratory tract - kidneys - and other organs - circulating C- ANCAs






10. Tumor suppressor mutated in wilms tumor






11. Aka trisomy 18 - mental retardation - prominent occiput - micrognathia (small jaw) - low::set ears - rocker::bottom feet - finger deformities - congenital heart dx






12. Defective in x- linked brutons agammaglobulinemia - B- cell tyrosine kinase






13. Defective cilia - sinusitis - bronchiectasis - situs inversus - sometimes hearing loss and male sterility






14. Paraneoplastic synd looks like myasthenia gravis - often small cell lung CA






15. Osteophytes at DIP joints






16. Paracentric inversion or translocation with 17 associated with papillary thyroid CA






17. Associated with 90% cases of ankylosing spondylitis - common in rheumatoid arthritis






18. Vaginal epithelial cell with stippled appearance due to adherent coccobacilli






19. Deficient hypoxanthine::guanine phosphoribosyltransferase (HGPRT) - low purine metabolism - high uric acid - thus gout - mental retardation - choreoathetosis - spasticity - self mutilation - aggressiveness






20. Modest elevated serum unconj bilirubin - due to decreased uptake by liver cells and reduced activity of glucuronyl transferase






21. Small round blue cell tumor of bone - long bones - kids - 11:22 transloc






22. Occurs in SLE - small vegitations on either or both surfaces of valves






23. Deficient hexosaminidase A - GM2 ganglioside accumulation - especially in neurons - CNS degeneration - mental/motor deterioration - blindness - cherry red spot on macula - death by 4 years of age






24. Variant of rheumatoid arthritis - splenmegally - neutropenia - RA






25. Aneurysm at small artery bifurcations






26. Aka mucocutaneous lymph node syndrome - acute self - limited - infants and young kids - acute necrotizing vasculitis of small and medium vessels - fever hemorrhagic edema of conjunctivae - lips and oral mucosa - and cervical LAD - can cause coronary






27. Pigmented iris hamartoma seen in neurofibromatosis






28. Aka angiokeratoma corporis diffusum universal - deficient a::galactosidase A - accumulate ceramide trihexoside - skin lesions angiokeratomas - fever - burning pain in extremities - cardiovascular and cerebrovascular involvement - death as adult by re






29. Paternal transmission del (15)(q11q13) - hypogonad - hypotonia - mental retardation - behavior probs - uncrontrolled appetite






30. Intracytoplasmic inclusions seen in leydig cell tumors p283






31. Polyostotic fibrous dysplasia - precocious puberty - caf






32. Appears as multiple wart - like lesions resembling condyloma accuminatum






33. Materal transmission del(15)(q11q13) - aka happy puppet syndrome - mental retardation - ataxia - seizures - inappropriate laughter






34. Lots of tumors - breast CA - soft tissue sarc - brain tumors - leukemias - has loss of p53 tumor suppressor gene






35. Deficient muscle phosphorylase - glycogen in skeletal muscle - cramps with exertion






36. 45 XO - female hypogonadism - hypothyroid - short - webbed neck - 1* amenorrhea p52






37. Sphingomyelin containing phagocytes seen in Niemman::Pick dx in liver - spleen - lymph nodes and skin






38. Aka trisomy 13 - mental retardation - microcephaly - micropthalmia - brain abnormalities - cleft lip/palate - polydactyly - rockerbottom feet - congenital heart dx






39. Deficient glucocerebrosidase - accumulation of glucocerebroside in cells of mononuclear phagocyte system 3 types ::






40. Downward displacement of cerebellar tonsils and medulla through foramen magnum






41. Malignant lymphoma with features resembling inflammatory disorder - young men - Reed Sternburg cells






42. Aka pulseless dx - inflammation and stenosis of medium and large sized arteries - often aortic arch thus aortic arch syndrome






43. Aka IgA nephropathy - deposition of IgA in mesangium - benign recurrent hematuria in kids following infection






44. Thiamine deficiency - cerebral dysfunction - aka alcoholic encephalopathy - hemorrhagic lesions in the mamillary bodies - confusion - ataxia - ophthalmoplegia - and memory loss plus confabulation p 105 and p115






45. Deficient glucose -6- phosphatase - accumulation of glycogen in liver and kidney - hepatomegaly - hypoglycemia






46. Variant of rheumatoid arthritis - aka juvenile rheumatoid arthritis






47. Triad of ovarian fibroma - ascites - hydrothorax






48. Mutation here causes pseudohypoparathyroidism






49. Area of focal interstitial myocardial inflammation characterized by fragmented collagen and fibrinoid material - by large cells (Anitschkow myocytes) and occasional multinucleated giant cells (Aschoff cells)






50. Nystagmus - intention tremor - scanning speech - seen in MS







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