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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Ovarian tumor resembling bladder transitional epith






2. Autoimmune thyroiditis - hyperthyroid - exophthalmos - increased in HLA DR3 and HLA B8 pos people






3. Pituitary insufficiency post - partum - low TSH ACTH






4. Minute neutrophilic abscesses found within parakeratotic stratum corneum in psoriasis






5. = MEN2a






6. Gene mutated in achondroplasia (most common form of dwarfism) - located at 4p16.3






7. Malignant lymphoma with features resembling inflammatory disorder - young men - Reed Sternburg cells






8. Sphingomyelin containing phagocytes seen in Niemman::Pick dx in liver - spleen - lymph nodes and skin






9. Seen in papillary thyroid CA






10. Autosomal recessive - neutropenia - albinism - cranial and peripheral neuropathy - tendency to develop repeated infections - abnormal WBCs (abnormal mictotubul formation and large cytoplasmic granules = lysosomes)






11. Vaginal epithelial cell with stippled appearance due to adherent coccobacilli






12. Gene product facilitates apoptosis - decreases bcl::2 and increases Bax






13. Chromosome 19 - allele common in alzheimers






14. Catastrophic adrenal insuff and vascular collapse - hemorrhagic necrosis of adrenal cortex






15. Severe unconj hyperbilirubinemia due to deficient glucuronyl transferase






16. 2/neu :: oncogene (aka c - erbB2) - in breast cancer = poor prognosis






17. Subcutaneous fibrosis of dorsum of penis






18. = MEN1






19. Seen in Down synd - small white spots on periphery of iris






20. Oligohydramnios causes fetus to be smashed






21. Thrombotic occlusion of major hepatic veins - abnormal pain - jaundice - hepatomegaly - acites - liver failure - assoc with polycythemia vera - hepatocellular CA - and other common neoplasms - may occur as a complication of pregnancy






22. B Thalassemia major






23. Seen in granuloma inguinale - multiple organisms filling large histiocytes






24. Hemangioblastoma or cavernous hemangioma of cerebellum - brainstem or retina - adenomas - cysts in liver - kidney - pancreas - and other organs - increased renal cell CA - gene = short arm of chromosome 3






25. Deficient a1 -4 glucosidase - accumulation of glycogen in liver - heart - skeletal muscle - cardiomegaly - muscle hypotonia - spelnomegaly - intractable hypoglycemia - death from cardiorespiratory failure before age 3






26. Aka infantile progressive spinal muscular atrophy - autosomal recessive - LMN disease - infants






27. Vasosmasm of small vessels - most often in fingers - seen with autoimmune dx like SLE - scleroderma and others (R in CREST) - recurrent vasospasm - always secondary to underlying disorder






28. Esophageal diverticulum just above upper esoph sphincter






29. Mucinous cell - characteristic of stomach CA met to ovary (krukenberg tumor)






30. Defective in x- linked brutons agammaglobulinemia - B- cell tyrosine kinase






31. Myc :: neuroblastoma amplicatiion correlates inversely with degree of differentiation






32. Seen in insulinoma - episodic hyperinsulinemia and hypoglycemia - CNS dysfunction - reversal of CNS probs with administration of glucose






33. Unknown etiology - necrotizing granulomatous vasculitis of small to medium sized vessels of the respiratory tract - kidneys - and other organs - circulating C- ANCAs






34. Aka angiokeratoma corporis diffusum universal - deficient a::galactosidase A - accumulate ceramide trihexoside - skin lesions angiokeratomas - fever - burning pain in extremities - cardiovascular and cerebrovascular involvement - death as adult by re






35. Defective cilia - sinusitis - bronchiectasis - situs inversus - sometimes hearing loss and male sterility






36. Iron deficient anemia associated with upper::esophageal web






37. 5p chromosome deletion - severe mental retardation - microcephaly - catlike cry - low birth weight - round face - hypertelorism (wide eyes)






38. Philadelphia chromosome - CML bcr abl fusion c - abl on 9 - bcr on 22






39. Deficient hexosaminidase A - GM2 ganglioside accumulation - especially in neurons - CNS degeneration - mental/motor deterioration - blindness - cherry red spot on macula - death by 4 years of age






40. Aka osteitis deformans - increased osteoclastic and osteoblastic activity






41. Ring of copper deposited around iris seen in Wilson






42. Aka antiglomerular basement membrane dx - antibodies against alveolar and glomerular basement membranes - linear immunoflorescence






43. Aka pulseless dx - inflammation and stenosis of medium and large sized arteries - often aortic arch thus aortic arch syndrome






44. Autoimmune hypothyroid - hurthle cells common






45. Aka hereditary hemorrhagic telangectasia - telangectasias in skin and mucous membranes - epistaxis - GI bleeds






46. Combination of hyperthyroidism - nodular goiter - absence of exophthalmos






47. Development of large pituitary adenomas following bilat adrenalectomy






48. Aka osteopetrosis - marble bone dx - dense skeleton - failure of osteoclastic activity






49. Diffuse nodular diabetic glomerulosclerosis






50. Hemihypertrophy - macroglossia - organomegaly - neonatal hypoglycemia - various embryonal tumors - deleted WT 2 gene