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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Aka chronic progressive histiocytosis - not as bad as Letterer Siwe






2. Protooncogene mutated in medulary thyroid CA (MENII)






3. Malabsorption syndrome - Tropheryma wippelii bacilli - small intestine commonly affected - arthralgias - cardiac - and neuro symptoms






4. Nystagmus - intention tremor - scanning speech - seen in MS






5. Lots of tumors - breast CA - soft tissue sarc - brain tumors - leukemias - has loss of p53 tumor suppressor gene






6. Aka neurofibromatosis - neurofibromas in skin - schwannomas of CN VIII - caf






7. Autosomal recessive - neutropenia - albinism - cranial and peripheral neuropathy - tendency to develop repeated infections - abnormal WBCs (abnormal mictotubul formation and large cytoplasmic granules = lysosomes)






8. Paternal transmission del (15)(q11q13) - hypogonad - hypotonia - mental retardation - behavior probs - uncrontrolled appetite






9. Myc :: neuroblastoma amplicatiion correlates inversely with degree of differentiation






10. Urethritis - conjunctivitis - arthritis - associated with venereal or intestinal infection






11. Associated with papillary thyroid CA






12. Tumor suppressor mutated in Von Recklinhousen






13. Aka lentigo maligna - precursor to lentigo maligna melanoma






14. Philadelphia chromosome - CML bcr abl fusion c - abl on 9 - bcr on 22






15. Aka hereditary hemorrhagic telangectasia - telangectasias in skin and mucous membranes - epistaxis - GI bleeds






16. Occurs in SLE - small vegitations on either or both surfaces of valves






17. Intracytoplasmic proximal dentritic eosinophilic inclusions consisting of actin seen in Alzheimers






18. Catastrophic adrenal insuff and vascular collapse - hemorrhagic necrosis of adrenal cortex






19. Paraneoplastic synd looks like myasthenia gravis - often small cell lung CA






20. X linked - aka immunodeficiency with thrombocytopenia and eczema - total immunoglobulins often normal - recurrent infections






21. Primary aldosteronism






22. Tennis racket shaped cytoplasmic inclusion seen in langerhans cells (so also seen in langerhan cell histiocytosis)






23. Diffuse nodular diabetic glomerulosclerosis






24. 2/neu :: oncogene (aka c - erbB2) - in breast cancer = poor prognosis






25. Autoimmune thyroiditis - hyperthyroid - exophthalmos - increased in HLA DR3 and HLA B8 pos people






26. Nuclei arranged in horseshoe - shaped pattern about periphery of cell - characteristic of but not specific for granulomatous TB (as opposed to a foreign body giant cell that has scattered nuclei)






27. Associated with Wegener granulomatosis






28. Follicular lymphoma IG heavy chain on 14 - bcl -2 oncogene on 18






29. Deficient debranching enzyme amylo -1 -6- glucosidase - glycogen in liver - heart - skeletal muscle - stunted growth - hepatomegaly - hypoglycemia






30. Abnormal WT 1 gene - intersexual disorders - nephropathy - wilms tumor






31. Variant of rheumatoid arthritis - splenmegally - neutropenia - RA






32. Oligohydramnios causes fetus to be smashed






33. Aka congenital megacolon - dilation of colon due to absence of ganglion cells






34. On lymph node biopsy - seen with Burkitt lymphoma






35. Associated with 90% cases of ankylosing spondylitis - common in rheumatoid arthritis






36. Port wine stain on face - ipsilateral glaucoma - vascular lesions of ocular choroidal tissue - extensive hemangiomatous involvement of meninges






37. Gene mutated in achondroplasia (most common form of dwarfism) - located at 4p16.3






38. Mesangial matrix material acculmulations seen in nodular glomerulosclerosis seen in diabetic nephropathy






39. Hemangioblastoma or cavernous hemangioma of cerebellum - brainstem or retina - adenomas - cysts in liver - kidney - pancreas - and other organs - increased renal cell CA - gene = short arm of chromosome 3






40. Materal transmission del(15)(q11q13) - aka happy puppet syndrome - mental retardation - ataxia - seizures - inappropriate laughter






41. Gene product facilitates apoptosis - decreases bcl::2 and increases Bax






42. Aka velocardiofacial syndrome and CATCH 22 syndrome - micro deletion of 22q11 - Cardiac abnormalities - Abnormal facies - T cell deficit due to thymic hypoplasia - Cleft palate - Hypocalcemia due to hypoparathyroidism - from poor development of 3rd a






43. Eosinophilic intracytoplasmic inclusions in hippocampus and purkinje cells seen in rabies infection






44. Intracytoplasmic inclusions seen in leydig cell tumors p283






45. Adenomatous polyps with tumors of CNS






46. Aka antiglomerular basement membrane dx - antibodies against alveolar and glomerular basement membranes - linear immunoflorescence






47. Seen in CLL - leukemic B- cells that are fragile






48. Single erythematous plaque on shaft of penis or scrotum






49. Renal tubular dysfunction - impaired reabsorption of glucose - amino acids - phosphate - and bicarb thus glycosuria - hyperphosphaturia - hypophosphatemia - aminoaciduria - systemic acidosis






50. Associated with breast alone (isn't one of these associated with prostate? Check)