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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Parkinsonism with autonomic dysfunction and orthostatic hypotension






2. Polyostotic fibrous dysplasia - precocious puberty - caf






3. Diffuse nodular diabetic glomerulosclerosis






4. Seen in granuloma inguinale - multiple organisms filling large histiocytes






5. Small round blue cell tumor of bone - long bones - kids - 11:22 transloc






6. Similar to Hurler - deficient L iduronosulfate sulfatase - accumulations of heparin sulfate and dermatan sulfate - hepatospenomegaly - micrognathia - retinal degeneration - joint stiffness - mental retardation - cardiac lesions






7. Autosomal recessive - conj hyperbilirubinemia - defect in bili transport - black color to liver






8. Tumor suppressor mutated in Von Recklinhousen






9. Pituitary insufficiency post - partum - low TSH ACTH






10. Combination of hyperthyroidism - nodular goiter - absence of exophthalmos






11. Aka velocardiofacial syndrome and CATCH 22 syndrome - micro deletion of 22q11 - Cardiac abnormalities - Abnormal facies - T cell deficit due to thymic hypoplasia - Cleft palate - Hypocalcemia due to hypoparathyroidism - from poor development of 3rd a






12. Aspirin toxicity seen in kids after acute febrile viral dx - microvesicular fatty change in liver and encephalopathy






13. Esophageal diverticulum just above upper esoph sphincter






14. Unknown etiology - necrotizing granulomatous vasculitis of small to medium sized vessels of the respiratory tract - kidneys - and other organs - circulating C- ANCAs






15. Defective in x- linked brutons agammaglobulinemia - B- cell tyrosine kinase






16. Different in that it is the primary disorder - recurrent vasospasm of small arteries and venules - pallor - cyanosis - fingers and toes - young healthy women






17. Materal transmission del(15)(q11q13) - aka happy puppet syndrome - mental retardation - ataxia - seizures - inappropriate laughter






18. Deficient glucose -6- phosphatase - accumulation of glycogen in liver and kidney - hepatomegaly - hypoglycemia






19. Chromosome 19 - allele common in alzheimers






20. Variant of rheumatoid arthritis - splenmegally - neutropenia - RA






21. X linked - absence of plasma cells and serum immunoglobulins - cell mediated immunity still ok - no germinal centers - recurrent bacterial infections - resistances to fungal and viral still - btk gene defect






22. Aka subcortical leukoencephalopathy - assoc with HTN - multiple lacunar infarcts and progressive demyelination in subcortical area






23. Acute promyelocytic leukemia PML gene on 15 and RARa on 17






24. Deficient debranching enzyme amylo -1 -6- glucosidase - glycogen in liver - heart - skeletal muscle - stunted growth - hepatomegaly - hypoglycemia






25. Paracentric inversion or translocation with 17 associated with papillary thyroid CA






26. Abnormal WT 1 gene - intersexual disorders - nephropathy - wilms tumor






27. Scheinker syndrome :: prion dx - fatal familial insomnia






28. Aka polycystic ovary syndrome - young women - amenorrhea - infertility - obesity - hirsutism






29. This comes in a wet variety and a dry one - they are both Vit B1 thiamine deficiency






30. Hereditary nephritis associated with nerve deafness and ocular disorders - mutation in gene for the a5 chain of type IV collagen






31. Subcutaneous fibrosis of dorsum of penis






32. Sphingomyelin containing phagocytes seen in Niemman::Pick dx in liver - spleen - lymph nodes and skin






33. Occurs in SLE - small vegitations on either or both surfaces of valves






34. Mucinous cell - characteristic of stomach CA met to ovary (krukenberg tumor)






35. Severe unconj hyperbilirubinemia due to deficient glucuronyl transferase






36. Port wine stain on face - ipsilateral glaucoma - vascular lesions of ocular choroidal tissue - extensive hemangiomatous involvement of meninges






37. Downward displacement of cerebellar tonsils and medulla through foramen magnum






38. Adenomatous polyps with tumors of CNS






39. Autosomal recessive - unusually large platelets - lack of 'GPIb IX V'






40. Tennis racket shaped cytoplasmic inclusion seen in langerhans cells (so also seen in langerhan cell histiocytosis)






41. X linked - aka immunodeficiency with thrombocytopenia and eczema - total immunoglobulins often normal - recurrent infections






42. Aka acute disseminated langerhans cell histiocytosis - aggressive - usually fatal - kids hepatosplenomegaly - LAD - pancytopenia - pulmonary involvement - recurrent infections






43. Malabsorption syndrome - Tropheryma wippelii bacilli - small intestine commonly affected - arthralgias - cardiac - and neuro symptoms






44. Also seen in urine of MM - stacks of RBCs - will have high ESR






45. Hamartomatous polyps in colon and small intest - freckles on lips - hands - genitalia - higher incidence of adeno CA of colon and other malignancies - stomach - breast - ovaries






46. Eczematoid lesion of nipple areola - large cells with clear 'halo like' area - invade epidermis - underlying ductal CA






47. Radiologic appearance of periostium in bone tumors






48. Seen in urine of patients with multiple myeloma - Ig light chain either k or l






49. Nuclei arranged in horseshoe - shaped pattern about periphery of cell - characteristic of but not specific for granulomatous TB (as opposed to a foreign body giant cell that has scattered nuclei)






50. Myc :: neuroblastoma amplicatiion correlates inversely with degree of differentiation