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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Aka polycystic ovary syndrome - young women - amenorrhea - infertility - obesity - hirsutism






2. Deficient glucocerebrosidase - accumulation of glucocerebroside in cells of mononuclear phagocyte system 3 types ::






3. Aka thromboangiitis obliterans - acute inflame of small and med arteries of extremities - extending to adjacent veins and nerves - young jewish men - painful ischemic dx - worse with smoking






4. Parkinsonism with autonomic dysfunction and orthostatic hypotension






5. Port wine stain on face - ipsilateral glaucoma - vascular lesions of ocular choroidal tissue - extensive hemangiomatous involvement of meninges






6. Hemihypertrophy - macroglossia - organomegaly - neonatal hypoglycemia - various embryonal tumors - deleted WT 2 gene






7. 45 XO - female hypogonadism - hypothyroid - short - webbed neck - 1* amenorrhea p52






8. Aka osteitis deformans - increased osteoclastic and osteoblastic activity






9. Burkitts c::myc is on 8 - IG heavy chain is on 14






10. Non::neoplastic tumor like masses - fibrous replacement of resorbed bone






11. Seen in urine of patients with multiple myeloma - Ig light chain either k or l






12. Follicular lymphoma IG heavy chain on 14 - bcl -2 oncogene on 18






13. Autosomal dominant - fatal - progressive degeneration of striatum and frontal cortex with neuronal depletion and gliosis






14. Vaginal epithelial cell with stippled appearance due to adherent coccobacilli






15. Occurs in SLE - small vegitations on either or both surfaces of valves






16. Thyroid replacement by fibrous tissue - unkown origin - mimics






17. Aka chronic progressive histiocytosis - not as bad as Letterer Siwe






18. Thiamine deficiency - cerebral dysfunction - aka alcoholic encephalopathy - hemorrhagic lesions in the mamillary bodies - confusion - ataxia - ophthalmoplegia - and memory loss plus confabulation p 105 and p115






19. Intracytoplasmic proximal dentritic eosinophilic inclusions consisting of actin seen in Alzheimers






20. Aka antiglomerular basement membrane dx - antibodies against alveolar and glomerular basement membranes - linear immunoflorescence






21. Tennis racket shaped cytoplasmic inclusion seen in langerhans cells (so also seen in langerhan cell histiocytosis)






22. Adenomatous polyps with tumors of CNS






23. Triad of ovarian fibroma - ascites - hydrothorax






24. Aka subcortical leukoencephalopathy - assoc with HTN - multiple lacunar infarcts and progressive demyelination in subcortical area






25. Lots of tumors - breast CA - soft tissue sarc - brain tumors - leukemias - has loss of p53 tumor suppressor gene






26. Seen in papillary thyroid CA






27. Located on xsome 6 - mutation here = hereditary hemochromatosis






28. X linked - absence of plasma cells and serum immunoglobulins - cell mediated immunity still ok - no germinal centers - recurrent bacterial infections - resistances to fungal and viral still - btk gene defect






29. Defective cilia - sinusitis - bronchiectasis - situs inversus - sometimes hearing loss and male sterility






30. Intracytoplasmic inclusions seen in leydig cell tumors p283






31. Clear cell renal tumor seen in kids






32. Downward displacement of cerebellar tonsils and medulla through foramen magnum






33. Seen in insulinoma - episodic hyperinsulinemia and hypoglycemia - CNS dysfunction - reversal of CNS probs with administration of glucose






34. Seen in CLL - leukemic B- cells that are fragile






35. B1 thiamine - B2 riboflavin - B3 niacin - B6 pyridoxine - B12 cobalamin - C ascorbic acid - D calciferol - E a::tocopherol






36. Impaired tubular reabsorption of tryptophan - pellagra::like manifestations






37. Manifestation of lymphplasmocytic lymphoma - B cell neoplasm






38. Subcutaneous fibrosis of dorsum of penis






39. Aka congenital megacolon - dilation of colon due to absence of ganglion cells






40. Nystagmus - intention tremor - scanning speech - seen in MS






41. Hamartomatous polyps in colon and small intest - freckles on lips - hands - genitalia - higher incidence of adeno CA of colon and other malignancies - stomach - breast - ovaries






42. = MEN1






43. Gene product facilitates apoptosis






44. Autoimmune hypothyroid - hurthle cells common






45. Iron deficient anemia associated with upper::esophageal web






46. Materal transmission del(15)(q11q13) - aka happy puppet syndrome - mental retardation - ataxia - seizures - inappropriate laughter






47. Deficient debranching enzyme amylo -1 -6- glucosidase - glycogen in liver - heart - skeletal muscle - stunted growth - hepatomegaly - hypoglycemia






48. Aka IgA nephropathy - deposition of IgA in mesangium - benign recurrent hematuria in kids following infection






49. Transloc seen in ewing sarcoma






50. Radiologic appearance of periostium in bone tumors






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