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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Aka thromboangiitis obliterans - acute inflame of small and med arteries of extremities - extending to adjacent veins and nerves - young jewish men - painful ischemic dx - worse with smoking






2. Non::neoplastic tumor like masses - fibrous replacement of resorbed bone






3. Lots of tumors - breast CA - soft tissue sarc - brain tumors - leukemias - has loss of p53 tumor suppressor gene






4. Osteophytes at PIP joints






5. = MEN1






6. Myc :: neuroblastoma amplicatiion correlates inversely with degree of differentiation






7. Autosomal dominant - fatal - progressive degeneration of striatum and frontal cortex with neuronal depletion and gliosis






8. Hereditary nephritis associated with nerve deafness and ocular disorders - mutation in gene for the a5 chain of type IV collagen






9. Aka hereditary hemorrhagic telangectasia - telangectasias in skin and mucous membranes - epistaxis - GI bleeds






10. Esophageal diverticulum just above upper esoph sphincter






11. Aka osteitis deformans - increased osteoclastic and osteoblastic activity






12. Subcutaneous fibrosis of dorsum of penis






13. X linked - absence of plasma cells and serum immunoglobulins - cell mediated immunity still ok - no germinal centers - recurrent bacterial infections - resistances to fungal and viral still - btk gene defect






14. Port wine stain on face - ipsilateral glaucoma - vascular lesions of ocular choroidal tissue - extensive hemangiomatous involvement of meninges






15. Primary adrenal failure






16. Hemangioblastoma or cavernous hemangioma of cerebellum - brainstem or retina - adenomas - cysts in liver - kidney - pancreas - and other organs - increased renal cell CA - gene = short arm of chromosome 3






17. Aka IgA nephropathy - deposition of IgA in mesangium - benign recurrent hematuria in kids following infection






18. Similar to paget breast - sometimes related to underlying adenoCA of sweat glands






19. Adenomatous polyps with tumors of CNS






20. Philadelphia chromosome - CML bcr abl fusion c - abl on 9 - bcr on 22






21. Aneurysm at small artery bifurcations






22. Single erythematous plaque on shaft of penis or scrotum






23. Aka polycystic ovary syndrome - young women - amenorrhea - infertility - obesity - hirsutism






24. Eosinophilic intracytoplasmic inclusions in hippocampus and purkinje cells seen in rabies infection






25. Oncogenes that code for p21 proteins which are membrane signalers






26. Similar to Hurler - deficient L iduronosulfate sulfatase - accumulations of heparin sulfate and dermatan sulfate - hepatospenomegaly - micrognathia - retinal degeneration - joint stiffness - mental retardation - cardiac lesions






27. Urethritis - conjunctivitis - arthritis - associated with venereal or intestinal infection






28. Aka allergic granulomatous angiitis - necrotizing vasculitis - variant of polyarteritis nodosa - involves pulmonary vasculature - peripheral eosinophilia - and asthma






29. Catastrophic adrenal insuff and vascular collapse - hemorrhagic necrosis of adrenal cortex






30. Gene product facilitates apoptosis






31. Tumor suppressor mutated in wilms tumor






32. 2/neu :: oncogene (aka c - erbB2) - in breast cancer = poor prognosis






33. Superclavicular lymph node identifying metastatic stomach CA






34. Vaginal epithelial cell with stippled appearance due to adherent coccobacilli






35. Defective in x- linked brutons agammaglobulinemia - B- cell tyrosine kinase






36. Aka mucocutaneous lymph node syndrome - acute self - limited - infants and young kids - acute necrotizing vasculitis of small and medium vessels - fever hemorrhagic edema of conjunctivae - lips and oral mucosa - and cervical LAD - can cause coronary






37. Aka neurofibromatosis - neurofibromas in skin - schwannomas of CN VIII - caf






38. Autosomal recessive - hepatitis - accumulation of copper due to transport problem - low ceruloplasmin seen - kayser fleischer rings in eyes






39. Paternal transmission del (15)(q11q13) - hypogonad - hypotonia - mental retardation - behavior probs - uncrontrolled appetite






40. Associated with papillary thyroid CA






41. Associated with Wegener granulomatosis






42. Autosomal recessive - unusually large platelets - lack of 'GPIb IX V'






43. Renal tubular dysfunction - impaired reabsorption of glucose - amino acids - phosphate - and bicarb thus glycosuria - hyperphosphaturia - hypophosphatemia - aminoaciduria - systemic acidosis






44. Similar to Dubin Johnson with no black liver






45. Paracentric inversion or translocation with 17 associated with papillary thyroid CA






46. X linked - aka immunodeficiency with thrombocytopenia and eczema - total immunoglobulins often normal - recurrent infections






47. Ovarian tumor resembling bladder transitional epith






48. This comes in a wet variety and a dry one - they are both Vit B1 thiamine deficiency






49. Thrombotic occlusion of major hepatic veins - abnormal pain - jaundice - hepatomegaly - acites - liver failure - assoc with polycythemia vera - hepatocellular CA - and other common neoplasms - may occur as a complication of pregnancy






50. = MEN2a







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