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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Paternal transmission del (15)(q11q13) - hypogonad - hypotonia - mental retardation - behavior probs - uncrontrolled appetite






2. Binucleated or multinucleated giant cell seen in Hodgkin dx






3. Aka subcortical leukoencephalopathy - assoc with HTN - multiple lacunar infarcts and progressive demyelination in subcortical area






4. Seen in papillary thyroid CA






5. Autosomal dominant - numerous adenomatous polyps along with osteomas and soft tissue tumors






6. Intra::alveolar hemosiderin - laden macrophages caused by RBCs from capillary rupture 2* to pulmonary HTN






7. Transloc seen in ewing sarcoma






8. Downward displacement of cerebellar tonsils and medulla through foramen magnum






9. Impaired tubular reabsorption of tryptophan - pellagra::like manifestations






10. Adenomatous polyps with tumors of CNS






11. Defective in x- linked brutons agammaglobulinemia - B- cell tyrosine kinase






12. Non::neoplastic tumor like masses - fibrous replacement of resorbed bone






13. Aka angiokeratoma corporis diffusum universal - deficient a::galactosidase A - accumulate ceramide trihexoside - skin lesions angiokeratomas - fever - burning pain in extremities - cardiovascular and cerebrovascular involvement - death as adult by re






14. Variant of rheumatoid arthritis - splenmegally - neutropenia - RA






15. Deficient hypoxanthine::guanine phosphoribosyltransferase (HGPRT) - low purine metabolism - high uric acid - thus gout - mental retardation - choreoathetosis - spasticity - self mutilation - aggressiveness






16. Radiologic appearance of periostium in bone tumors






17. Mucinous cell - characteristic of stomach CA met to ovary (krukenberg tumor)






18. Esophageal diverticulum just above upper esoph sphincter






19. Associated with papillary thyroid CA






20. Seen in granuloma inguinale - multiple organisms filling large histiocytes






21. Mesangial matrix material acculmulations seen in nodular glomerulosclerosis seen in diabetic nephropathy






22. Similar to Hurler - deficient L iduronosulfate sulfatase - accumulations of heparin sulfate and dermatan sulfate - hepatospenomegaly - micrognathia - retinal degeneration - joint stiffness - mental retardation - cardiac lesions






23. Myc :: neuroblastoma amplicatiion correlates inversely with degree of differentiation






24. Aka superior sulcus tumor - seen in bronchogenic CA - often with Horner's






25. Aka neurofibromatosis - neurofibromas in skin - schwannomas of CN VIII - caf






26. Lots of tumors - breast CA - soft tissue sarc - brain tumors - leukemias - has loss of p53 tumor suppressor gene






27. Urethritis - conjunctivitis - arthritis - associated with venereal or intestinal infection






28. Deficient fibrillin (constituent of microfibrils) - arachnodactyly - ectopia lentis - aortic aneurysm - mitral valve prolapsed






29. Aka infantile progressive spinal muscular atrophy - autosomal recessive - LMN disease - infants






30. Catastrophic adrenal insuff and vascular collapse - hemorrhagic necrosis of adrenal cortex






31. 45 XO - female hypogonadism - hypothyroid - short - webbed neck - 1* amenorrhea p52






32. Scheinker syndrome :: prion dx - fatal familial insomnia






33. Infectious disorder - caused postencephalitic parkinsonism






34. Superclavicular lymph node identifying metastatic stomach CA






35. Primary adrenal failure






36. Defective cilia - sinusitis - bronchiectasis - situs inversus - sometimes hearing loss and male sterility






37. Appears as multiple wart - like lesions resembling condyloma accuminatum






38. Acute promyelocytic leukemia PML gene on 15 and RARa on 17






39. Paraneoplastic synd looks like myasthenia gravis - often small cell lung CA






40. Small round blue cell tumor of bone - long bones - kids - 11:22 transloc






41. Deficient a1 -4 glucosidase - accumulation of glycogen in liver - heart - skeletal muscle - cardiomegaly - muscle hypotonia - spelnomegaly - intractable hypoglycemia - death from cardiorespiratory failure before age 3






42. X linked - absence of plasma cells and serum immunoglobulins - cell mediated immunity still ok - no germinal centers - recurrent bacterial infections - resistances to fungal and viral still - btk gene defect






43. Hereditary nephritis associated with nerve deafness and ocular disorders - mutation in gene for the a5 chain of type IV collagen






44. Aka congenital megacolon - dilation of colon due to absence of ganglion cells






45. Clear cell renal tumor seen in kids






46. Seen in hyperacute rejection - = acute inflammation - fibrinoid necrosis of small vessels - and extensive thrombosis






47. Similar to Dubin Johnson with no black liver






48. Aka mucocutaneous lymph node syndrome - acute self - limited - infants and young kids - acute necrotizing vasculitis of small and medium vessels - fever hemorrhagic edema of conjunctivae - lips and oral mucosa - and cervical LAD - can cause coronary






49. Nystagmus - intention tremor - scanning speech - seen in MS






50. Severe unconj hyperbilirubinemia due to deficient glucuronyl transferase







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