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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Gene mutated in achondroplasia (most common form of dwarfism) - located at 4p16.3






2. Similar to paget breast - sometimes related to underlying adenoCA of sweat glands






3. Thrombotic occlusion of major hepatic veins - abnormal pain - jaundice - hepatomegaly - acites - liver failure - assoc with polycythemia vera - hepatocellular CA - and other common neoplasms - may occur as a complication of pregnancy






4. Thyroid replacement by fibrous tissue - unkown origin - mimics






5. Aka acute disseminated langerhans cell histiocytosis - aggressive - usually fatal - kids hepatosplenomegaly - LAD - pancytopenia - pulmonary involvement - recurrent infections






6. Epithelial cells with eosinophilc granular cytoplasm seen in hashimoto






7. Severe unconj hyperbilirubinemia due to deficient glucuronyl transferase






8. Acute inflammatory demyelinating dx primarily involving peripheral nerves






9. Triad of ovarian fibroma - ascites - hydrothorax






10. Aka osteopetrosis - marble bone dx - dense skeleton - failure of osteoclastic activity






11. Osteophytes at DIP joints






12. Myc :: neuroblastoma amplicatiion correlates inversely with degree of differentiation






13. Seen in granuloma inguinale - multiple organisms filling large histiocytes






14. Autosomal recessive - neutropenia - albinism - cranial and peripheral neuropathy - tendency to develop repeated infections - abnormal WBCs (abnormal mictotubul formation and large cytoplasmic granules = lysosomes)






15. Burkitts c::myc is on 8 - IG heavy chain is on 14






16. Aspirin toxicity seen in kids after acute febrile viral dx - microvesicular fatty change in liver and encephalopathy






17. Malabsorption syndrome - Tropheryma wippelii bacilli - small intestine commonly affected - arthralgias - cardiac - and neuro symptoms






18. Hereditary nephritis associated with nerve deafness and ocular disorders - mutation in gene for the a5 chain of type IV collagen






19. Aka thromboangiitis obliterans - acute inflame of small and med arteries of extremities - extending to adjacent veins and nerves - young jewish men - painful ischemic dx - worse with smoking






20. Minute neutrophilic abscesses found within parakeratotic stratum corneum in psoriasis






21. Tennis racket shaped cytoplasmic inclusion seen in langerhans cells (so also seen in langerhan cell histiocytosis)






22. Associated with breast alone (isn't one of these associated with prostate? Check)






23. Aka congenital megacolon - dilation of colon due to absence of ganglion cells






24. Pituitary insufficiency post - partum - low TSH ACTH






25. Hamartomatous polyps in colon and small intest - freckles on lips - hands - genitalia - higher incidence of adeno CA of colon and other malignancies - stomach - breast - ovaries






26. Primary aldosteronism






27. Hemangioblastoma or cavernous hemangioma of cerebellum - brainstem or retina - adenomas - cysts in liver - kidney - pancreas - and other organs - increased renal cell CA - gene = short arm of chromosome 3






28. Binucleated or multinucleated giant cell seen in Hodgkin dx






29. At least 2 X and one Y - hypogonadism - tall - gynecomastia - low testosterone - high pituitary gonadotropins - infertility -






30. Unknown etiology - necrotizing granulomatous vasculitis of small to medium sized vessels of the respiratory tract - kidneys - and other organs - circulating C- ANCAs






31. B Thalassemia major






32. Also seen in urine of MM - stacks of RBCs - will have high ESR






33. On lymph node biopsy - seen with Burkitt lymphoma






34. Mucopolysaccharidosis - deficient a L iduronidase - accumulations of heparin sulfate and dermatan sulfate in heart - brain - liver - and other organs - progressive - hepatosplenomagaly - dwarfism - gargoyle - like facies - stubby fingers - corneal cl






35. Malignant lymphoma with features resembling inflammatory disorder - young men - Reed Sternburg cells






36. Aka allergic granulomatous angiitis - necrotizing vasculitis - variant of polyarteritis nodosa - involves pulmonary vasculature - peripheral eosinophilia - and asthma






37. Aka hereditary hemorrhagic telangectasia - telangectasias in skin and mucous membranes - epistaxis - GI bleeds






38. Intracytoplasmic inclusions seen in leydig cell tumors p283






39. Small follicles filled with eosinophilic secretion - diagnostic feature of granulose cell tumor






40. Defective cilia - sinusitis - bronchiectasis - situs inversus - sometimes hearing loss and male sterility






41. Aka velocardiofacial syndrome and CATCH 22 syndrome - micro deletion of 22q11 - Cardiac abnormalities - Abnormal facies - T cell deficit due to thymic hypoplasia - Cleft palate - Hypocalcemia due to hypoparathyroidism - from poor development of 3rd a






42. Paraneoplastic synd looks like myasthenia gravis - often small cell lung CA






43. Primary adrenal failure






44. Abnormal WT 1 gene - intersexual disorders - nephropathy - wilms tumor






45. = MEN2a






46. Single erythematous plaque on shaft of penis or scrotum






47. Aka trisomy 18 - mental retardation - prominent occiput - micrognathia (small jaw) - low::set ears - rocker::bottom feet - finger deformities - congenital heart dx






48. Urethritis - conjunctivitis - arthritis - associated with venereal or intestinal infection






49. Autosomal dominant - fatal - progressive degeneration of striatum and frontal cortex with neuronal depletion and gliosis






50. Aka infantile progressive spinal muscular atrophy - autosomal recessive - LMN disease - infants