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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Tumor suppressor mutated in Von Recklinhousen






2. Small round eosinophilic masses found in dieing hepatocytes often containing chromatin remnants seen in viral hepatitis






3. Iron deficient anemia associated with upper::esophageal web






4. Similar to paget breast - sometimes related to underlying adenoCA of sweat glands






5. Autosomal recessive - hepatitis - accumulation of copper due to transport problem - low ceruloplasmin seen - kayser fleischer rings in eyes






6. Epithelial cells with eosinophilc granular cytoplasm seen in hashimoto






7. Osteophytes at DIP joints






8. Infectious disorder - caused postencephalitic parkinsonism






9. Single erythematous plaque on shaft of penis or scrotum






10. At least 2 X and one Y - hypogonadism - tall - gynecomastia - low testosterone - high pituitary gonadotropins - infertility -






11. Aka IgA nephropathy - deposition of IgA in mesangium - benign recurrent hematuria in kids following infection






12. Aka trisomy 18 - mental retardation - prominent occiput - micrognathia (small jaw) - low::set ears - rocker::bottom feet - finger deformities - congenital heart dx






13. Pigmented iris hamartoma seen in neurofibromatosis






14. Paracentric inversion or translocation with 17 associated with papillary thyroid CA






15. Aka pulseless dx - inflammation and stenosis of medium and large sized arteries - often aortic arch thus aortic arch syndrome






16. Downward displacement of cerebellar tonsils and medulla through foramen magnum






17. Severe unconj hyperbilirubinemia due to deficient glucuronyl transferase






18. Acute inflammatory demyelinating dx primarily involving peripheral nerves






19. Asbestosis - yellow - brown - rod shaped body with clubbed ends - stain with Prussian blue






20. Eczematoid lesion of nipple areola - large cells with clear 'halo like' area - invade epidermis - underlying ductal CA






21. Oncogenes that code for p21 proteins which are membrane signalers






22. Thrombotic occlusion of major hepatic veins - abnormal pain - jaundice - hepatomegaly - acites - liver failure - assoc with polycythemia vera - hepatocellular CA - and other common neoplasms - may occur as a complication of pregnancy






23. Renal tubular dysfunction - impaired reabsorption of glucose - amino acids - phosphate - and bicarb thus glycosuria - hyperphosphaturia - hypophosphatemia - aminoaciduria - systemic acidosis






24. Aka hereditary hemorrhagic telangectasia - telangectasias in skin and mucous membranes - epistaxis - GI bleeds






25. X linked - aka immunodeficiency with thrombocytopenia and eczema - total immunoglobulins often normal - recurrent infections






26. Esophageal diverticulum just above upper esoph sphincter






27. Associated with Wegener granulomatosis






28. Nuclei arranged in horseshoe - shaped pattern about periphery of cell - characteristic of but not specific for granulomatous TB (as opposed to a foreign body giant cell that has scattered nuclei)






29. Autoimmune thyroiditis - hyperthyroid - exophthalmos - increased in HLA DR3 and HLA B8 pos people






30. Vasosmasm of small vessels - most often in fingers - seen with autoimmune dx like SLE - scleroderma and others (R in CREST) - recurrent vasospasm - always secondary to underlying disorder






31. Unknown etiology - necrotizing granulomatous vasculitis of small to medium sized vessels of the respiratory tract - kidneys - and other organs - circulating C- ANCAs






32. Combination of hyperthyroidism - nodular goiter - absence of exophthalmos






33. Scheinker syndrome :: prion dx - fatal familial insomnia






34. Manifestation of lymphplasmocytic lymphoma - B cell neoplasm






35. Aka osteopetrosis - marble bone dx - dense skeleton - failure of osteoclastic activity






36. Autosomal dominant - numerous adenomatous polyps along with osteomas and soft tissue tumors






37. Aka velocardiofacial syndrome and CATCH 22 syndrome - micro deletion of 22q11 - Cardiac abnormalities - Abnormal facies - T cell deficit due to thymic hypoplasia - Cleft palate - Hypocalcemia due to hypoparathyroidism - from poor development of 3rd a






38. Mucinous cell - characteristic of stomach CA met to ovary (krukenberg tumor)






39. Associated with papillary thyroid CA






40. Autosomal recessive - unusually large platelets - lack of 'GPIb IX V'






41. Associated with breast alone (isn't one of these associated with prostate? Check)






42. Non::neoplastic tumor like masses - fibrous replacement of resorbed bone






43. Aka angiokeratoma corporis diffusum universal - deficient a::galactosidase A - accumulate ceramide trihexoside - skin lesions angiokeratomas - fever - burning pain in extremities - cardiovascular and cerebrovascular involvement - death as adult by re






44. = MEN2a






45. Deficient fibrillin (constituent of microfibrils) - arachnodactyly - ectopia lentis - aortic aneurysm - mitral valve prolapsed






46. Seen in hyperacute rejection - = acute inflammation - fibrinoid necrosis of small vessels - and extensive thrombosis






47. Aka infantile progressive spinal muscular atrophy - autosomal recessive - LMN disease - infants






48. 45 XO - female hypogonadism - hypothyroid - short - webbed neck - 1* amenorrhea p52






49. Gene product facilitates apoptosis






50. Seen in CLL - leukemic B- cells that are fragile






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