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Test your basic knowledge |
USMLE Brs Pathology Vocab
Start Test
Study First
Subjects
:
health-sciences
,
usmle
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Intra::alveolar hemosiderin - laden macrophages caused by RBCs from capillary rupture 2* to pulmonary HTN
Donovan bodies
Mediterranean anemia or Cooley Anemia
Heart failure cells
Hutchinson freckle
2. Aka angiokeratoma corporis diffusum universal - deficient a::galactosidase A - accumulate ceramide trihexoside - skin lesions angiokeratomas - fever - burning pain in extremities - cardiovascular and cerebrovascular involvement - death as adult by re
Fabry dx
C ANCA
Waldenstrom Macroglobulinemia
Kimmelstiel Wilson nodules
3. Peripheral neuropathy - atrophy of muscles - wet - high output cardiac failure - DCM - AV shunting - hypervolemia
Denys Drash syndrome
Hashimoto thyroiditis
Niemann Pick dx
Dry beriberi
4. Deficient muscle phosphorylase - glycogen in skeletal muscle - cramps with exertion
McArdle syndrome
Virchow node
Kawasaki dx
Bax
5. Oncogenes that code for p21 proteins which are membrane signalers
Bernard Soulier dx
Ras oncogenes
Koilocyte
Werdnig Hoffman syndrome
6. Deficient a1 -4 glucosidase - accumulation of glycogen in liver - heart - skeletal muscle - cardiomegaly - muscle hypotonia - spelnomegaly - intractable hypoglycemia - death from cardiorespiratory failure before age 3
Kayser Fleischer ring
Pompe dx
Hirschsprung dx
Hirano bodies
7. Development of large pituitary adenomas following bilat adrenalectomy
Arthus reaction
Donovan bodies
Nelson syndrome
ret
8. Vaginal epithelial cell with stippled appearance due to adherent coccobacilli
Wilms tumor
Clue cell
Gerstmann Straussler
Lesch Nyhan syndrome
9. Autosomal recessive - hepatitis - accumulation of copper due to transport problem - low ceruloplasmin seen - kayser fleischer rings in eyes
Wilson dx
Kimmelsteil Wilson dx
Bernard Soulier dx
Rotor syndrome
10. Variant of rheumatoid arthritis - aka juvenile rheumatoid arthritis
Meigs syndrome
Cori dx
Still disease
Brushfield spots
11. B1 thiamine - B2 riboflavin - B3 niacin - B6 pyridoxine - B12 cobalamin - C ascorbic acid - D calciferol - E a::tocopherol
Names of Vitamins
Prader willi syndrome
Cori dx
Osler Weber Rendu syndrome
12. Similar to paget breast - sometimes related to underlying adenoCA of sweat glands
Paget dx of vulva
Denys Drash syndrome
Libman Sacks endocarditis
Potter sequence
13. Tumor suppressor mutated in Von Recklinhousen
Bernard Soulier dx
Brushfield spots
NF1
Reinke crystal
14. Aka pituitary cachexia - generalized panhypopituitarism
Alport syndrome
Donovan bodies
Pompe dx
Simmonds dx
15. Nystagmus - intention tremor - scanning speech - seen in MS
GNAS1
Heberden nodes
Charcot triad
Wilson dx
16. Triad of ovarian fibroma - ascites - hydrothorax
Angelman syndrome
Meigs syndrome
Shy Drager syndrome
Osler Weber Rendu syndrome
17. Non::neoplastic tumor like masses - fibrous replacement of resorbed bone
Rb gene
BRCA1
Brown tumor
Heberden nodes
18. Seen in urine of patients with multiple myeloma - Ig light chain either k or l
Rotor syndrome
Charcot triad
Kartagener syndrome
Bense Jones protein
19. Thyroid replacement by fibrous tissue - unkown origin - mimics
Paget dx of bone
Buerger dx
FGFR3
Reidel thyroiditis
20. Subcutaneous fibrosis of dorsum of penis
ret PTC
Edwards syndrome
Peyronie dx
Aschoff body
21. Aggressive B- cell lymphoma - EBV - starry sky appearance - c myc
Gaucher dx
Hartnup dx
Burkitt lymphoma
Wernicke Korsakoff syndrome
22. Deficient sphingomyelinase - accumulation of sphingomyelin in phagocytes - foamy histiocytes in liver - spleen - lymph nodes - skin - hepatosplenomegaly - anemia fever - occasional neuro degeneration - half have cherry red spot macula
Cori dx
Orphan annie nuclei
Niemann Pick dx
Birbeck granule
23. Retinoblastoma on chromosome 13
Heberden nodes
Buerger dx
Kimmelstiel Wilson nodules
Rb gene
24. Metastatic stomach CA to ovary
Munro abscesses
Foamy histiocyte
Aschoff body
Krukenberg tumor
25. Protooncogene mutated in medulary thyroid CA (MENII)
Pompe dx
Henoch Schonlein Purpura
ret
BRCA1
26. X linked - absence of plasma cells and serum immunoglobulins - cell mediated immunity still ok - no germinal centers - recurrent bacterial infections - resistances to fungal and viral still - btk gene defect
Mediterranean anemia or Cooley Anemia
Bcl2
Potter sequence
Brutons Agammaglobulinemia
27. Aka mucocutaneous lymph node syndrome - acute self - limited - infants and young kids - acute necrotizing vasculitis of small and medium vessels - fever hemorrhagic edema of conjunctivae - lips and oral mucosa - and cervical LAD - can cause coronary
Cori dx
Gerstmann Straussler
Kawasaki dx
Paget dx of vulva
28. Defective in x- linked brutons agammaglobulinemia - B- cell tyrosine kinase
Beriberi
Tay Sachs dx
Heart failure cells
Btk gene
29. Vasosmasm of small vessels - most often in fingers - seen with autoimmune dx like SLE - scleroderma and others (R in CREST) - recurrent vasospasm - always secondary to underlying disorder
Raynaud phenomenon
Charcot Bouchard aneurysm
Hirschsprung dx
Osler Weber Rendu syndrome
30. Seen in granuloma inguinale - multiple organisms filling large histiocytes
Ferruginous body
Turner syndrome
Virchow node
Donovan bodies
31. B Thalassemia major
Clue cell
Mediterranean anemia or Cooley Anemia
Whipple dx
Lynch syndrome
32. Autoimmune hypothyroid - hurthle cells common
Hashimoto thyroiditis
Reed Sternburg cell
Kimmelstiel Wilson nodules
Call Exner bodies
33. Aka osteitis deformans - increased osteoclastic and osteoblastic activity
GNAS1
Peyronie dx
Paget dx of bone
Graves dx
34. Gene mutated in achondroplasia (most common form of dwarfism) - located at 4p16.3
FGFR3
Signet ring cell
Hunter syndrome
Marfan syndrome
35. Myc :: neuroblastoma amplicatiion correlates inversely with degree of differentiation
Wermer syndrome
N
Names of Vitamins
Call Exner bodies
36. Sphingomyelin containing phagocytes seen in Niemman::Pick dx in liver - spleen - lymph nodes and skin
Btk gene
Gaucher dx
Foamy histiocyte
Brutons Agammaglobulinemia
37. Aka lentigo maligna - precursor to lentigo maligna melanoma
Arthus reaction
Hirschsprung dx
Hutchinson freckle
Bense Jones protein
38. Modest elevated serum unconj bilirubin - due to decreased uptake by liver cells and reduced activity of glucuronyl transferase
Graves dx
Libman Sacks endocarditis
Conn syndrome
Gilbert syndrome
39. This comes in a wet variety and a dry one - they are both Vit B1 thiamine deficiency
Beckwith Weidemann syndrome
Beriberi
Hunter syndrome
Cori dx
40. Deficient glucose -6- phosphatase - accumulation of glycogen in liver and kidney - hepatomegaly - hypoglycemia
Kawasaki dx
Hutchinson freckle
Von Gierke dx
Call Exner bodies
41. Malabsorption syndrome - Tropheryma wippelii bacilli - small intestine commonly affected - arthralgias - cardiac - and neuro symptoms
Aschoff body
PIG A
HER
Whipple dx
42. Aka trisomy 13 - mental retardation - microcephaly - micropthalmia - brain abnormalities - cleft lip/palate - polydactyly - rockerbottom feet - congenital heart dx
Wermer syndrome
Peyronie dx
Patau syndrome
11:22
43. Asbestosis - yellow - brown - rod shaped body with clubbed ends - stain with Prussian blue
Waterhouse Friderichsen syndrome
Hurthle cell
Werdnig Hoffman syndrome
Ferruginous body
44. Tennis racket shaped cytoplasmic inclusion seen in langerhans cells (so also seen in langerhan cell histiocytosis)
Felty syndrome
Meigs syndrome
Bax
Birbeck granule
45. Similar to Hurler - deficient L iduronosulfate sulfatase - accumulations of heparin sulfate and dermatan sulfate - hepatospenomegaly - micrognathia - retinal degeneration - joint stiffness - mental retardation - cardiac lesions
Hunter syndrome
Pancoast tumor
Sipple syndrome
Aschoff body
46. Ovarian tumor resembling bladder transitional epith
Berger dx
Felty syndrome
Osler Weber Rendu syndrome
Brenner tumor
47. Esophageal diverticulum just above upper esoph sphincter
Buerger dx
Zenker diverticulum
Paget dx of bone
DiGeorge syndrome
48. Seen in CLL - leukemic B- cells that are fragile
Negri bodies
Smudge cells
Von economo encephalitis
McArdle syndrome
49. Combination of hyperthyroidism - nodular goiter - absence of exophthalmos
Raynaud disease
Plummer dx
Names of Vitamins
Paget dx of bone
50. 2/neu :: oncogene (aka c - erbB2) - in breast cancer = poor prognosis
HER
E4 allele of apoprotein E
Chediak Higashi syndrome
Smudge cells