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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
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  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Aneurysm at small artery bifurcations






2. Aggressive B- cell lymphoma - EBV - starry sky appearance - c myc






3. Small round eosinophilic masses found in dieing hepatocytes often containing chromatin remnants seen in viral hepatitis






4. Aka congenital megacolon - dilation of colon due to absence of ganglion cells






5. Aka velocardiofacial syndrome and CATCH 22 syndrome - micro deletion of 22q11 - Cardiac abnormalities - Abnormal facies - T cell deficit due to thymic hypoplasia - Cleft palate - Hypocalcemia due to hypoparathyroidism - from poor development of 3rd a






6. Deficient hexosaminidase A - GM2 ganglioside accumulation - especially in neurons - CNS degeneration - mental/motor deterioration - blindness - cherry red spot on macula - death by 4 years of age






7. Non::neoplastic tumor like masses - fibrous replacement of resorbed bone






8. Seen in insulinoma - episodic hyperinsulinemia and hypoglycemia - CNS dysfunction - reversal of CNS probs with administration of glucose






9. Different in that it is the primary disorder - recurrent vasospasm of small arteries and venules - pallor - cyanosis - fingers and toes - young healthy women






10. Hemihypertrophy - macroglossia - organomegaly - neonatal hypoglycemia - various embryonal tumors - deleted WT 2 gene






11. Malabsorption syndrome - Tropheryma wippelii bacilli - small intestine commonly affected - arthralgias - cardiac - and neuro symptoms






12. Asbestosis - yellow - brown - rod shaped body with clubbed ends - stain with Prussian blue






13. Seen in papillary thyroid CA






14. Hemorrhagic urticaria of extensor surgaces of arms - legs - and buttocks - with fever - arthralgias - and GI renal involvement similar to IgA nephropathy - associated with URIs






15. Aspirin toxicity seen in kids after acute febrile viral dx - microvesicular fatty change in liver and encephalopathy






16. Materal transmission del(15)(q11q13) - aka happy puppet syndrome - mental retardation - ataxia - seizures - inappropriate laughter






17. Aka mucocutaneous lymph node syndrome - acute self - limited - infants and young kids - acute necrotizing vasculitis of small and medium vessels - fever hemorrhagic edema of conjunctivae - lips and oral mucosa - and cervical LAD - can cause coronary






18. Thiamine deficiency - cerebral dysfunction - aka alcoholic encephalopathy - hemorrhagic lesions in the mamillary bodies - confusion - ataxia - ophthalmoplegia - and memory loss plus confabulation p 105 and p115






19. Tumor suppressor mutated in breast and ovary






20. Seen in Down synd - small white spots on periphery of iris






21. Port wine stain on face - ipsilateral glaucoma - vascular lesions of ocular choroidal tissue - extensive hemangiomatous involvement of meninges






22. Superclavicular lymph node identifying metastatic stomach CA






23. Aka hereditary hemorrhagic telangectasia - telangectasias in skin and mucous membranes - epistaxis - GI bleeds






24. Seen in granuloma inguinale - multiple organisms filling large histiocytes






25. Development of large pituitary adenomas following bilat adrenalectomy






26. Epithelial cells with eosinophilc granular cytoplasm seen in hashimoto






27. Hereditary nonpolyposis colon cancer - DNA repair genes messed up






28. 5p chromosome deletion - severe mental retardation - microcephaly - catlike cry - low birth weight - round face - hypertelorism (wide eyes)






29. = MEN2a






30. Similar to Dubin Johnson with no black liver






31. Small round blue cell tumor of bone - long bones - kids - 11:22 transloc






32. Renal tubular dysfunction - impaired reabsorption of glucose - amino acids - phosphate - and bicarb thus glycosuria - hyperphosphaturia - hypophosphatemia - aminoaciduria - systemic acidosis






33. Area of focal interstitial myocardial inflammation characterized by fragmented collagen and fibrinoid material - by large cells (Anitschkow myocytes) and occasional multinucleated giant cells (Aschoff cells)






34. Malignant lymphoma with features resembling inflammatory disorder - young men - Reed Sternburg cells






35. This comes in a wet variety and a dry one - they are both Vit B1 thiamine deficiency






36. Follicular lymphoma IG heavy chain on 14 - bcl -2 oncogene on 18






37. Dysplastic cell seen in HPV






38. Autosomal recessive - unusually large platelets - lack of 'GPIb IX V'






39. Paraneoplastic synd looks like myasthenia gravis - often small cell lung CA






40. Downward displacement of cerebellar tonsils and medulla through foramen magnum






41. Associated with 90% cases of ankylosing spondylitis - common in rheumatoid arthritis






42. Severe unconj hyperbilirubinemia due to deficient glucuronyl transferase






43. Aka osteitis deformans - increased osteoclastic and osteoblastic activity






44. Philadelphia chromosome - CML bcr abl fusion c - abl on 9 - bcr on 22






45. Autosomal recessive - neutropenia - albinism - cranial and peripheral neuropathy - tendency to develop repeated infections - abnormal WBCs (abnormal mictotubul formation and large cytoplasmic granules = lysosomes)






46. Gene product facilitates apoptosis - decreases bcl::2 and increases Bax






47. Variant of rheumatoid arthritis - splenmegally - neutropenia - RA






48. Aka angiokeratoma corporis diffusum universal - deficient a::galactosidase A - accumulate ceramide trihexoside - skin lesions angiokeratomas - fever - burning pain in extremities - cardiovascular and cerebrovascular involvement - death as adult by re






49. Deficient hypoxanthine::guanine phosphoribosyltransferase (HGPRT) - low purine metabolism - high uric acid - thus gout - mental retardation - choreoathetosis - spasticity - self mutilation - aggressiveness






50. Oncogenes that code for p21 proteins which are membrane signalers







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