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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Aka mucocutaneous lymph node syndrome - acute self - limited - infants and young kids - acute necrotizing vasculitis of small and medium vessels - fever hemorrhagic edema of conjunctivae - lips and oral mucosa - and cervical LAD - can cause coronary






2. DsDNA antibodies and Sm Smith antigen = highly specific for SLE






3. Acute promyelocytic leukemia PML gene on 15 and RARa on 17






4. Aka chronic progressive histiocytosis - not as bad as Letterer Siwe






5. Primary adrenal failure






6. Aka infantile progressive spinal muscular atrophy - autosomal recessive - LMN disease - infants






7. Aka osteopetrosis - marble bone dx - dense skeleton - failure of osteoclastic activity






8. Hemangioblastoma or cavernous hemangioma of cerebellum - brainstem or retina - adenomas - cysts in liver - kidney - pancreas - and other organs - increased renal cell CA - gene = short arm of chromosome 3






9. Aka acute disseminated langerhans cell histiocytosis - aggressive - usually fatal - kids hepatosplenomegaly - LAD - pancytopenia - pulmonary involvement - recurrent infections






10. Malabsorption syndrome - Tropheryma wippelii bacilli - small intestine commonly affected - arthralgias - cardiac - and neuro symptoms






11. Osteophytes at DIP joints






12. Aka angiokeratoma corporis diffusum universal - deficient a::galactosidase A - accumulate ceramide trihexoside - skin lesions angiokeratomas - fever - burning pain in extremities - cardiovascular and cerebrovascular involvement - death as adult by re






13. Lots of tumors - breast CA - soft tissue sarc - brain tumors - leukemias - has loss of p53 tumor suppressor gene






14. Aka congenital megacolon - dilation of colon due to absence of ganglion cells






15. Tumor suppressor common in familial polyposis coli and adenoCA of colon as well as other tumors






16. Autoimmune hypothyroid - hurthle cells common






17. Gene product inhibits apoptosis






18. Seen in papillary thyroid CA






19. X linked - absence of plasma cells and serum immunoglobulins - cell mediated immunity still ok - no germinal centers - recurrent bacterial infections - resistances to fungal and viral still - btk gene defect






20. Aspirin toxicity seen in kids after acute febrile viral dx - microvesicular fatty change in liver and encephalopathy






21. Associated with Wegener granulomatosis






22. Small round blue cell tumor of bone - long bones - kids - 11:22 transloc






23. Also seen in urine of MM - stacks of RBCs - will have high ESR






24. Metastatic stomach CA to ovary






25. Small follicles filled with eosinophilic secretion - diagnostic feature of granulose cell tumor






26. Radiologic appearance of periostium in bone tumors






27. X linked - aka immunodeficiency with thrombocytopenia and eczema - total immunoglobulins often normal - recurrent infections






28. Clear cell renal tumor seen in kids






29. Parkinsonism with autonomic dysfunction and orthostatic hypotension






30. Aka pulseless dx - inflammation and stenosis of medium and large sized arteries - often aortic arch thus aortic arch syndrome






31. Adenomatous polyps with tumors of CNS






32. Occurs in SLE - small vegitations on either or both surfaces of valves






33. = MEN1






34. Paternal transmission del (15)(q11q13) - hypogonad - hypotonia - mental retardation - behavior probs - uncrontrolled appetite






35. Aka polycystic ovary syndrome - young women - amenorrhea - infertility - obesity - hirsutism






36. Oncogenes that code for p21 proteins which are membrane signalers






37. Autoimmune thyroiditis - hyperthyroid - exophthalmos - increased in HLA DR3 and HLA B8 pos people






38. Different in that it is the primary disorder - recurrent vasospasm of small arteries and venules - pallor - cyanosis - fingers and toes - young healthy women






39. Modest elevated serum unconj bilirubin - due to decreased uptake by liver cells and reduced activity of glucuronyl transferase






40. Hemorrhagic urticaria of extensor surgaces of arms - legs - and buttocks - with fever - arthralgias - and GI renal involvement similar to IgA nephropathy - associated with URIs






41. Thrombotic occlusion of major hepatic veins - abnormal pain - jaundice - hepatomegaly - acites - liver failure - assoc with polycythemia vera - hepatocellular CA - and other common neoplasms - may occur as a complication of pregnancy






42. Gene mutated in achondroplasia (most common form of dwarfism) - located at 4p16.3






43. Thiamine deficiency - cerebral dysfunction - aka alcoholic encephalopathy - hemorrhagic lesions in the mamillary bodies - confusion - ataxia - ophthalmoplegia - and memory loss plus confabulation p 105 and p115






44. Tumor suppressor mutated in Von Recklinhousen






45. Deficient sphingomyelinase - accumulation of sphingomyelin in phagocytes - foamy histiocytes in liver - spleen - lymph nodes - skin - hepatosplenomegaly - anemia fever - occasional neuro degeneration - half have cherry red spot macula






46. Aka pituitary cachexia - generalized panhypopituitarism






47. Protooncogene mutated in medulary thyroid CA (MENII)






48. 5p chromosome deletion - severe mental retardation - microcephaly - catlike cry - low birth weight - round face - hypertelorism (wide eyes)






49. Subcutaneous fibrosis of dorsum of penis






50. Malignant lymphoma with features resembling inflammatory disorder - young men - Reed Sternburg cells