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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Gene product facilitates apoptosis - decreases bcl::2 and increases Bax






2. Located on xsome 6 - mutation here = hereditary hemochromatosis






3. Vaginal epithelial cell with stippled appearance due to adherent coccobacilli






4. B1 thiamine - B2 riboflavin - B3 niacin - B6 pyridoxine - B12 cobalamin - C ascorbic acid - D calciferol - E a::tocopherol






5. Mutation here causes pseudohypoparathyroidism






6. Similar to paget breast - sometimes related to underlying adenoCA of sweat glands






7. X linked - absence of plasma cells and serum immunoglobulins - cell mediated immunity still ok - no germinal centers - recurrent bacterial infections - resistances to fungal and viral still - btk gene defect






8. Associated with 90% cases of ankylosing spondylitis - common in rheumatoid arthritis






9. Associated with breast alone (isn't one of these associated with prostate? Check)






10. Seen in papillary thyroid CA






11. Intracytoplasmic inclusions seen in leydig cell tumors p283






12. Paternal transmission del (15)(q11q13) - hypogonad - hypotonia - mental retardation - behavior probs - uncrontrolled appetite






13. Minute neutrophilic abscesses found within parakeratotic stratum corneum in psoriasis






14. Aka trisomy 13 - mental retardation - microcephaly - micropthalmia - brain abnormalities - cleft lip/palate - polydactyly - rockerbottom feet - congenital heart dx






15. Variant of rheumatoid arthritis - splenmegally - neutropenia - RA






16. Pigmented iris hamartoma seen in neurofibromatosis






17. At least 2 X and one Y - hypogonadism - tall - gynecomastia - low testosterone - high pituitary gonadotropins - infertility -






18. Small round eosinophilic masses found in dieing hepatocytes often containing chromatin remnants seen in viral hepatitis






19. Acute inflammatory demyelinating dx primarily involving peripheral nerves






20. Thyroid replacement by fibrous tissue - unkown origin - mimics






21. Hemangioblastoma or cavernous hemangioma of cerebellum - brainstem or retina - adenomas - cysts in liver - kidney - pancreas - and other organs - increased renal cell CA - gene = short arm of chromosome 3






22. Mucopolysaccharidosis - deficient a L iduronidase - accumulations of heparin sulfate and dermatan sulfate in heart - brain - liver - and other organs - progressive - hepatosplenomagaly - dwarfism - gargoyle - like facies - stubby fingers - corneal cl






23. Variant of rheumatoid arthritis - aka juvenile rheumatoid arthritis






24. Hemorrhagic urticaria of extensor surgaces of arms - legs - and buttocks - with fever - arthralgias - and GI renal involvement similar to IgA nephropathy - associated with URIs






25. Small round blue cell tumor of bone - long bones - kids - 11:22 transloc






26. Epithelial cells with eosinophilc granular cytoplasm seen in hashimoto






27. Adenomatous polyps with tumors of CNS






28. Deficient hypoxanthine::guanine phosphoribosyltransferase (HGPRT) - low purine metabolism - high uric acid - thus gout - mental retardation - choreoathetosis - spasticity - self mutilation - aggressiveness






29. Retinoblastoma on chromosome 13






30. Nuclei arranged in horseshoe - shaped pattern about periphery of cell - characteristic of but not specific for granulomatous TB (as opposed to a foreign body giant cell that has scattered nuclei)






31. Radiologic appearance of periostium in bone tumors






32. Eosinophilic intracytoplasmic inclusions in hippocampus and purkinje cells seen in rabies infection






33. Defective in x- linked brutons agammaglobulinemia - B- cell tyrosine kinase






34. Mutation = paroxysmal nocturnal hemoglobinuria






35. Tumor suppressor mutated in breast and ovary






36. Intracytoplasmic proximal dentritic eosinophilic inclusions consisting of actin seen in Alzheimers






37. Single erythematous plaque on shaft of penis or scrotum






38. Deficient hexosaminidase A - GM2 ganglioside accumulation - especially in neurons - CNS degeneration - mental/motor deterioration - blindness - cherry red spot on macula - death by 4 years of age






39. Primary aldosteronism






40. Triad of ovarian fibroma - ascites - hydrothorax






41. Seen in CLL - leukemic B- cells that are fragile






42. Aka acute disseminated langerhans cell histiocytosis - aggressive - usually fatal - kids hepatosplenomegaly - LAD - pancytopenia - pulmonary involvement - recurrent infections






43. Osteophytes at DIP joints






44. Different in that it is the primary disorder - recurrent vasospasm of small arteries and venules - pallor - cyanosis - fingers and toes - young healthy women






45. Paracentric inversion or translocation with 17 associated with papillary thyroid CA






46. Dysplastic cell seen in HPV






47. Malignant lymphoma with features resembling inflammatory disorder - young men - Reed Sternburg cells






48. Hamartomatous polyps in colon and small intest - freckles on lips - hands - genitalia - higher incidence of adeno CA of colon and other malignancies - stomach - breast - ovaries






49. Infectious disorder - caused postencephalitic parkinsonism






50. Aka allergic granulomatous angiitis - necrotizing vasculitis - variant of polyarteritis nodosa - involves pulmonary vasculature - peripheral eosinophilia - and asthma