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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Radiologic appearance of periostium in bone tumors






2. Seen in hyperacute rejection - = acute inflammation - fibrinoid necrosis of small vessels - and extensive thrombosis






3. Deficient sphingomyelinase - accumulation of sphingomyelin in phagocytes - foamy histiocytes in liver - spleen - lymph nodes - skin - hepatosplenomegaly - anemia fever - occasional neuro degeneration - half have cherry red spot macula






4. Different in that it is the primary disorder - recurrent vasospasm of small arteries and venules - pallor - cyanosis - fingers and toes - young healthy women






5. Aka infantile progressive spinal muscular atrophy - autosomal recessive - LMN disease - infants






6. Aka IgA nephropathy - deposition of IgA in mesangium - benign recurrent hematuria in kids following infection






7. Associated with breast alone (isn't one of these associated with prostate? Check)






8. Thiamine deficiency - cerebral dysfunction - aka alcoholic encephalopathy - hemorrhagic lesions in the mamillary bodies - confusion - ataxia - ophthalmoplegia - and memory loss plus confabulation p 105 and p115






9. Port wine stain on face - ipsilateral glaucoma - vascular lesions of ocular choroidal tissue - extensive hemangiomatous involvement of meninges






10. Aka osteitis deformans - increased osteoclastic and osteoblastic activity






11. Gene product facilitates apoptosis






12. Materal transmission del(15)(q11q13) - aka happy puppet syndrome - mental retardation - ataxia - seizures - inappropriate laughter






13. Aka acute disseminated langerhans cell histiocytosis - aggressive - usually fatal - kids hepatosplenomegaly - LAD - pancytopenia - pulmonary involvement - recurrent infections






14. Transloc seen in ewing sarcoma






15. Aka thromboangiitis obliterans - acute inflame of small and med arteries of extremities - extending to adjacent veins and nerves - young jewish men - painful ischemic dx - worse with smoking






16. Retinoblastoma on chromosome 13






17. Deficient hypoxanthine::guanine phosphoribosyltransferase (HGPRT) - low purine metabolism - high uric acid - thus gout - mental retardation - choreoathetosis - spasticity - self mutilation - aggressiveness






18. Minute neutrophilic abscesses found within parakeratotic stratum corneum in psoriasis






19. Defective cilia - sinusitis - bronchiectasis - situs inversus - sometimes hearing loss and male sterility






20. Hereditary nephritis associated with nerve deafness and ocular disorders - mutation in gene for the a5 chain of type IV collagen






21. Intra::alveolar hemosiderin - laden macrophages caused by RBCs from capillary rupture 2* to pulmonary HTN






22. Aspirin toxicity seen in kids after acute febrile viral dx - microvesicular fatty change in liver and encephalopathy






23. Also seen in urine of MM - stacks of RBCs - will have high ESR






24. Deficient muscle phosphorylase - glycogen in skeletal muscle - cramps with exertion






25. Seen in urine of patients with multiple myeloma - Ig light chain either k or l






26. Eosinophilic intracytoplasmic inclusions in hippocampus and purkinje cells seen in rabies infection






27. Malignant lymphoma with features resembling inflammatory disorder - young men - Reed Sternburg cells






28. 5p chromosome deletion - severe mental retardation - microcephaly - catlike cry - low birth weight - round face - hypertelorism (wide eyes)






29. Impaired tubular reabsorption of tryptophan - pellagra::like manifestations






30. B1 thiamine - B2 riboflavin - B3 niacin - B6 pyridoxine - B12 cobalamin - C ascorbic acid - D calciferol - E a::tocopherol






31. Aka antiglomerular basement membrane dx - antibodies against alveolar and glomerular basement membranes - linear immunoflorescence






32. Clear cell renal tumor seen in kids






33. Binucleated or multinucleated giant cell seen in Hodgkin dx






34. Deficient a1 -4 glucosidase - accumulation of glycogen in liver - heart - skeletal muscle - cardiomegaly - muscle hypotonia - spelnomegaly - intractable hypoglycemia - death from cardiorespiratory failure before age 3






35. Osteophytes at PIP joints






36. Autosomal recessive - hepatitis - accumulation of copper due to transport problem - low ceruloplasmin seen - kayser fleischer rings in eyes






37. Hamartomatous polyps in colon and small intest - freckles on lips - hands - genitalia - higher incidence of adeno CA of colon and other malignancies - stomach - breast - ovaries






38. Follicular lymphoma IG heavy chain on 14 - bcl -2 oncogene on 18






39. Aneurysm at small artery bifurcations






40. Intracytoplasmic inclusions seen in leydig cell tumors p283






41. Deficient glucose -6- phosphatase - accumulation of glycogen in liver and kidney - hepatomegaly - hypoglycemia






42. Gene mutated in achondroplasia (most common form of dwarfism) - located at 4p16.3






43. Thrombotic occlusion of major hepatic veins - abnormal pain - jaundice - hepatomegaly - acites - liver failure - assoc with polycythemia vera - hepatocellular CA - and other common neoplasms - may occur as a complication of pregnancy






44. Malabsorption syndrome - Tropheryma wippelii bacilli - small intestine commonly affected - arthralgias - cardiac - and neuro symptoms






45. Hemangioblastoma or cavernous hemangioma of cerebellum - brainstem or retina - adenomas - cysts in liver - kidney - pancreas - and other organs - increased renal cell CA - gene = short arm of chromosome 3






46. Combination of hyperthyroidism - nodular goiter - absence of exophthalmos






47. Located on xsome 6 - mutation here = hereditary hemochromatosis






48. Autosomal recessive - conj hyperbilirubinemia - defect in bili transport - black color to liver






49. Aka allergic granulomatous angiitis - necrotizing vasculitis - variant of polyarteritis nodosa - involves pulmonary vasculature - peripheral eosinophilia - and asthma






50. Lots of tumors - breast CA - soft tissue sarc - brain tumors - leukemias - has loss of p53 tumor suppressor gene