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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Deficient hypoxanthine::guanine phosphoribosyltransferase (HGPRT) - low purine metabolism - high uric acid - thus gout - mental retardation - choreoathetosis - spasticity - self mutilation - aggressiveness






2. Seen in hyperacute rejection - = acute inflammation - fibrinoid necrosis of small vessels - and extensive thrombosis






3. Scheinker syndrome :: prion dx - fatal familial insomnia






4. = MEN1






5. Primary adrenal failure






6. Diffuse nodular diabetic glomerulosclerosis






7. Aka acute disseminated langerhans cell histiocytosis - aggressive - usually fatal - kids hepatosplenomegaly - LAD - pancytopenia - pulmonary involvement - recurrent infections






8. Deficient sphingomyelinase - accumulation of sphingomyelin in phagocytes - foamy histiocytes in liver - spleen - lymph nodes - skin - hepatosplenomegaly - anemia fever - occasional neuro degeneration - half have cherry red spot macula






9. Esophageal diverticulum just above upper esoph sphincter






10. Adenomatous polyps with tumors of CNS






11. Associated with breast alone (isn't one of these associated with prostate? Check)






12. 45 XO - female hypogonadism - hypothyroid - short - webbed neck - 1* amenorrhea p52






13. B Thalassemia major






14. Aka thromboangiitis obliterans - acute inflame of small and med arteries of extremities - extending to adjacent veins and nerves - young jewish men - painful ischemic dx - worse with smoking






15. Defective in x- linked brutons agammaglobulinemia - B- cell tyrosine kinase






16. Manifestation of lymphplasmocytic lymphoma - B cell neoplasm






17. Nystagmus - intention tremor - scanning speech - seen in MS






18. Aka subcortical leukoencephalopathy - assoc with HTN - multiple lacunar infarcts and progressive demyelination in subcortical area






19. Occurs in SLE - small vegitations on either or both surfaces of valves






20. Aka lentigo maligna - precursor to lentigo maligna melanoma






21. Retinoblastoma on chromosome 13






22. Mucinous cell - characteristic of stomach CA met to ovary (krukenberg tumor)






23. 5p chromosome deletion - severe mental retardation - microcephaly - catlike cry - low birth weight - round face - hypertelorism (wide eyes)






24. Downward displacement of cerebellar tonsils and medulla through foramen magnum






25. Variant of rheumatoid arthritis - aka juvenile rheumatoid arthritis






26. Tennis racket shaped cytoplasmic inclusion seen in langerhans cells (so also seen in langerhan cell histiocytosis)






27. Aka congenital megacolon - dilation of colon due to absence of ganglion cells






28. Small round eosinophilic masses found in dieing hepatocytes often containing chromatin remnants seen in viral hepatitis






29. Seen in papillary thyroid CA






30. Aspirin toxicity seen in kids after acute febrile viral dx - microvesicular fatty change in liver and encephalopathy






31. Deficient a1 -4 glucosidase - accumulation of glycogen in liver - heart - skeletal muscle - cardiomegaly - muscle hypotonia - spelnomegaly - intractable hypoglycemia - death from cardiorespiratory failure before age 3






32. Deficient glucocerebrosidase - accumulation of glucocerebroside in cells of mononuclear phagocyte system 3 types ::






33. Oncogenes that code for p21 proteins which are membrane signalers






34. Combination of hyperthyroidism - nodular goiter - absence of exophthalmos






35. This comes in a wet variety and a dry one - they are both Vit B1 thiamine deficiency






36. Associated with papillary thyroid CA






37. Modest elevated serum unconj bilirubin - due to decreased uptake by liver cells and reduced activity of glucuronyl transferase






38. Aka polycystic ovary syndrome - young women - amenorrhea - infertility - obesity - hirsutism






39. Protooncogene mutated in medulary thyroid CA (MENII)






40. Port wine stain on face - ipsilateral glaucoma - vascular lesions of ocular choroidal tissue - extensive hemangiomatous involvement of meninges






41. Intra::alveolar hemosiderin - laden macrophages caused by RBCs from capillary rupture 2* to pulmonary HTN






42. X linked - aka immunodeficiency with thrombocytopenia and eczema - total immunoglobulins often normal - recurrent infections






43. Pituitary insufficiency post - partum - low TSH ACTH






44. Dysplastic cell seen in HPV






45. Autosomal recessive - conj hyperbilirubinemia - defect in bili transport - black color to liver






46. Superclavicular lymph node identifying metastatic stomach CA






47. Acute promyelocytic leukemia PML gene on 15 and RARa on 17






48. Seen in insulinoma - episodic hyperinsulinemia and hypoglycemia - CNS dysfunction - reversal of CNS probs with administration of glucose






49. At least 2 X and one Y - hypogonadism - tall - gynecomastia - low testosterone - high pituitary gonadotropins - infertility -






50. Subcutaneous fibrosis of dorsum of penis