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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Impaired tubular reabsorption of tryptophan - pellagra::like manifestations






2. Malabsorption syndrome - Tropheryma wippelii bacilli - small intestine commonly affected - arthralgias - cardiac - and neuro symptoms






3. Primary adrenal failure






4. Thrombotic occlusion of major hepatic veins - abnormal pain - jaundice - hepatomegaly - acites - liver failure - assoc with polycythemia vera - hepatocellular CA - and other common neoplasms - may occur as a complication of pregnancy






5. Gene product inhibits apoptosis






6. Malignant lymphoma with features resembling inflammatory disorder - young men - Reed Sternburg cells






7. Oncogenes that code for p21 proteins which are membrane signalers






8. Eczematoid lesion of nipple areola - large cells with clear 'halo like' area - invade epidermis - underlying ductal CA






9. Manifestation of lymphplasmocytic lymphoma - B cell neoplasm






10. Deficient fibrillin (constituent of microfibrils) - arachnodactyly - ectopia lentis - aortic aneurysm - mitral valve prolapsed






11. Aka pulseless dx - inflammation and stenosis of medium and large sized arteries - often aortic arch thus aortic arch syndrome






12. Autosomal recessive - unusually large platelets - lack of 'GPIb IX V'






13. Hemangioblastoma or cavernous hemangioma of cerebellum - brainstem or retina - adenomas - cysts in liver - kidney - pancreas - and other organs - increased renal cell CA - gene = short arm of chromosome 3






14. Deficient a1 -4 glucosidase - accumulation of glycogen in liver - heart - skeletal muscle - cardiomegaly - muscle hypotonia - spelnomegaly - intractable hypoglycemia - death from cardiorespiratory failure before age 3






15. Small follicles filled with eosinophilic secretion - diagnostic feature of granulose cell tumor






16. Tumor suppressor mutated in Von Recklinhousen






17. Single erythematous plaque on shaft of penis or scrotum






18. Burkitts c::myc is on 8 - IG heavy chain is on 14






19. Seen in granuloma inguinale - multiple organisms filling large histiocytes






20. Autosomal dominant - numerous adenomatous polyps along with osteomas and soft tissue tumors






21. Iron deficient anemia associated with upper::esophageal web






22. Seen in hyperacute rejection - = acute inflammation - fibrinoid necrosis of small vessels - and extensive thrombosis






23. Aka congenital megacolon - dilation of colon due to absence of ganglion cells






24. Aka antiglomerular basement membrane dx - antibodies against alveolar and glomerular basement membranes - linear immunoflorescence






25. Chromosome 19 - allele common in alzheimers






26. Deficient sphingomyelinase - accumulation of sphingomyelin in phagocytes - foamy histiocytes in liver - spleen - lymph nodes - skin - hepatosplenomegaly - anemia fever - occasional neuro degeneration - half have cherry red spot macula






27. Autosomal dominant - fatal - progressive degeneration of striatum and frontal cortex with neuronal depletion and gliosis






28. Infectious disorder - caused postencephalitic parkinsonism






29. Aka infantile progressive spinal muscular atrophy - autosomal recessive - LMN disease - infants






30. Aka osteitis deformans - increased osteoclastic and osteoblastic activity






31. Deficient glucocerebrosidase - accumulation of glucocerebroside in cells of mononuclear phagocyte system 3 types ::






32. Similar to paget breast - sometimes related to underlying adenoCA of sweat glands






33. Combination of hyperthyroidism - nodular goiter - absence of exophthalmos






34. Mutation = paroxysmal nocturnal hemoglobinuria






35. Aka hereditary hemorrhagic telangectasia - telangectasias in skin and mucous membranes - epistaxis - GI bleeds






36. Esophageal diverticulum just above upper esoph sphincter






37. Thiamine deficiency - cerebral dysfunction - aka alcoholic encephalopathy - hemorrhagic lesions in the mamillary bodies - confusion - ataxia - ophthalmoplegia - and memory loss plus confabulation p 105 and p115






38. Hemorrhagic urticaria of extensor surgaces of arms - legs - and buttocks - with fever - arthralgias - and GI renal involvement similar to IgA nephropathy - associated with URIs






39. Aka trisomy 13 - mental retardation - microcephaly - micropthalmia - brain abnormalities - cleft lip/palate - polydactyly - rockerbottom feet - congenital heart dx






40. Downward displacement of cerebellar tonsils and medulla through foramen magnum






41. Triad of ovarian fibroma - ascites - hydrothorax






42. Peripheral neuropathy - atrophy of muscles - wet - high output cardiac failure - DCM - AV shunting - hypervolemia






43. Deficient debranching enzyme amylo -1 -6- glucosidase - glycogen in liver - heart - skeletal muscle - stunted growth - hepatomegaly - hypoglycemia






44. Primary aldosteronism






45. Superclavicular lymph node identifying metastatic stomach CA






46. Aka acute disseminated langerhans cell histiocytosis - aggressive - usually fatal - kids hepatosplenomegaly - LAD - pancytopenia - pulmonary involvement - recurrent infections






47. Mucopolysaccharidosis - deficient a L iduronidase - accumulations of heparin sulfate and dermatan sulfate in heart - brain - liver - and other organs - progressive - hepatosplenomagaly - dwarfism - gargoyle - like facies - stubby fingers - corneal cl






48. Aka trisomy 18 - mental retardation - prominent occiput - micrognathia (small jaw) - low::set ears - rocker::bottom feet - finger deformities - congenital heart dx






49. Follicular lymphoma IG heavy chain on 14 - bcl -2 oncogene on 18






50. Aspirin toxicity seen in kids after acute febrile viral dx - microvesicular fatty change in liver and encephalopathy