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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Aka congenital megacolon - dilation of colon due to absence of ganglion cells






2. Mutation = paroxysmal nocturnal hemoglobinuria






3. 45 XO - female hypogonadism - hypothyroid - short - webbed neck - 1* amenorrhea p52






4. Seen in CLL - leukemic B- cells that are fragile






5. Primary adrenal failure






6. Acute promyelocytic leukemia PML gene on 15 and RARa on 17






7. Acute inflammatory demyelinating dx primarily involving peripheral nerves






8. Chromosome 19 - allele common in alzheimers






9. = MEN1






10. Radiologic appearance of periostium in bone tumors






11. Paternal transmission del (15)(q11q13) - hypogonad - hypotonia - mental retardation - behavior probs - uncrontrolled appetite






12. Deficient hypoxanthine::guanine phosphoribosyltransferase (HGPRT) - low purine metabolism - high uric acid - thus gout - mental retardation - choreoathetosis - spasticity - self mutilation - aggressiveness






13. Retinoblastoma on chromosome 13






14. Superclavicular lymph node identifying metastatic stomach CA






15. Osteophytes at PIP joints






16. Minute neutrophilic abscesses found within parakeratotic stratum corneum in psoriasis






17. Seen in insulinoma - episodic hyperinsulinemia and hypoglycemia - CNS dysfunction - reversal of CNS probs with administration of glucose






18. X linked - absence of plasma cells and serum immunoglobulins - cell mediated immunity still ok - no germinal centers - recurrent bacterial infections - resistances to fungal and viral still - btk gene defect






19. Aka chronic progressive histiocytosis - not as bad as Letterer Siwe






20. Aka allergic granulomatous angiitis - necrotizing vasculitis - variant of polyarteritis nodosa - involves pulmonary vasculature - peripheral eosinophilia - and asthma






21. Myc :: neuroblastoma amplicatiion correlates inversely with degree of differentiation






22. DsDNA antibodies and Sm Smith antigen = highly specific for SLE






23. Development of large pituitary adenomas following bilat adrenalectomy






24. Aka velocardiofacial syndrome and CATCH 22 syndrome - micro deletion of 22q11 - Cardiac abnormalities - Abnormal facies - T cell deficit due to thymic hypoplasia - Cleft palate - Hypocalcemia due to hypoparathyroidism - from poor development of 3rd a






25. Deficient glucocerebrosidase - accumulation of glucocerebroside in cells of mononuclear phagocyte system 3 types ::






26. Manifestation of lymphplasmocytic lymphoma - B cell neoplasm






27. Diffuse nodular diabetic glomerulosclerosis






28. Transloc seen in ewing sarcoma






29. Gene mutated in achondroplasia (most common form of dwarfism) - located at 4p16.3






30. Severe unconj hyperbilirubinemia due to deficient glucuronyl transferase






31. Variant of rheumatoid arthritis - splenmegally - neutropenia - RA






32. Autosomal recessive - hepatitis - accumulation of copper due to transport problem - low ceruloplasmin seen - kayser fleischer rings in eyes






33. Deficient muscle phosphorylase - glycogen in skeletal muscle - cramps with exertion






34. Asbestosis - yellow - brown - rod shaped body with clubbed ends - stain with Prussian blue






35. Aka subcortical leukoencephalopathy - assoc with HTN - multiple lacunar infarcts and progressive demyelination in subcortical area






36. Aka trisomy 18 - mental retardation - prominent occiput - micrognathia (small jaw) - low::set ears - rocker::bottom feet - finger deformities - congenital heart dx






37. Catastrophic adrenal insuff and vascular collapse - hemorrhagic necrosis of adrenal cortex






38. Peripheral neuropathy - atrophy of muscles - wet - high output cardiac failure - DCM - AV shunting - hypervolemia






39. Clear cell renal tumor seen in kids






40. Intracytoplasmic proximal dentritic eosinophilic inclusions consisting of actin seen in Alzheimers






41. Materal transmission del(15)(q11q13) - aka happy puppet syndrome - mental retardation - ataxia - seizures - inappropriate laughter






42. Different in that it is the primary disorder - recurrent vasospasm of small arteries and venules - pallor - cyanosis - fingers and toes - young healthy women






43. Vasosmasm of small vessels - most often in fingers - seen with autoimmune dx like SLE - scleroderma and others (R in CREST) - recurrent vasospasm - always secondary to underlying disorder






44. Aka infantile progressive spinal muscular atrophy - autosomal recessive - LMN disease - infants






45. Renal tubular dysfunction - impaired reabsorption of glucose - amino acids - phosphate - and bicarb thus glycosuria - hyperphosphaturia - hypophosphatemia - aminoaciduria - systemic acidosis






46. Oligohydramnios causes fetus to be smashed






47. Similar to paget breast - sometimes related to underlying adenoCA of sweat glands






48. Deficient sphingomyelinase - accumulation of sphingomyelin in phagocytes - foamy histiocytes in liver - spleen - lymph nodes - skin - hepatosplenomegaly - anemia fever - occasional neuro degeneration - half have cherry red spot macula






49. Paracentric inversion or translocation with 17 associated with papillary thyroid CA






50. Downward displacement of cerebellar tonsils and medulla through foramen magnum