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Test your basic knowledge |
USMLE Brs Pathology Vocab
Start Test
Study First
Subjects
:
health-sciences
,
usmle
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Different in that it is the primary disorder - recurrent vasospasm of small arteries and venules - pallor - cyanosis - fingers and toes - young healthy women
Raynaud disease
ret
Still disease
ret PTC
2. Acute promyelocytic leukemia PML gene on 15 and RARa on 17
Names of Vitamins
HLA B27 antigen
15:17
Bernard Soulier dx
3. Tennis racket shaped cytoplasmic inclusion seen in langerhans cells (so also seen in langerhan cell histiocytosis)
Fabry dx
Birbeck granule
Von Hippel Lindau dx
Kimmelsteil Wilson dx
4. Defective in x- linked brutons agammaglobulinemia - B- cell tyrosine kinase
Whipple dx
Btk gene
Ras oncogenes
Plummer dx
5. Scheinker syndrome :: prion dx - fatal familial insomnia
Patau syndrome
Plummer dx
Gerstmann Straussler
Zenker diverticulum
6. Vasosmasm of small vessels - most often in fingers - seen with autoimmune dx like SLE - scleroderma and others (R in CREST) - recurrent vasospasm - always secondary to underlying disorder
Wegener granulomatosis
Raynaud phenomenon
Donovan bodies
APC
7. Renal tubular dysfunction - impaired reabsorption of glucose - amino acids - phosphate - and bicarb thus glycosuria - hyperphosphaturia - hypophosphatemia - aminoaciduria - systemic acidosis
Arthus reaction
Werdnig Hoffman syndrome
Fanconi syndrome
ret
8. 2/neu :: oncogene (aka c - erbB2) - in breast cancer = poor prognosis
Hirschsprung dx
HER
Bense Jones protein
Krukenberg tumor
9. Aka acute disseminated langerhans cell histiocytosis - aggressive - usually fatal - kids hepatosplenomegaly - LAD - pancytopenia - pulmonary involvement - recurrent infections
Guillain Barre syndrome
Letterer Siwe dx
Hashimoto thyroiditis
Paget dx of bone
10. Located on xsome 6 - mutation here = hereditary hemochromatosis
Hfe gene
Kartagener syndrome
Negri bodies
Chediak Higashi syndrome
11. Aka allergic granulomatous angiitis - necrotizing vasculitis - variant of polyarteritis nodosa - involves pulmonary vasculature - peripheral eosinophilia - and asthma
Reinke crystal
Churg Strauss syndrome
Waterhouse Friderichsen syndrome
Heart failure cells
12. Associated with Wegener granulomatosis
Still disease
Albers SCHonberg dx
C ANCA
Kawasaki dx
13. Osteophytes at PIP joints
Plummer dx
Bouchard nodes
ret
Hirano bodies
14. Tumor suppressor mutated in Von Recklinhousen
Donovan bodies
Peyronie dx
NF1
Hurthle cell
15. Thyroid replacement by fibrous tissue - unkown origin - mimics
ret PTC
Reidel thyroiditis
Rb gene
Hutchinson freckle
16. Aka osteopetrosis - marble bone dx - dense skeleton - failure of osteoclastic activity
Von Recklinhousen dx
Albers SCHonberg dx
Birbeck granule
Beckwith Weidemann syndrome
17. Hemangioblastoma or cavernous hemangioma of cerebellum - brainstem or retina - adenomas - cysts in liver - kidney - pancreas - and other organs - increased renal cell CA - gene = short arm of chromosome 3
Charcot triad
Ras oncogenes
E4 allele of apoprotein E
Von Hippel Lindau dx
18. Autosomal recessive - unusually large platelets - lack of 'GPIb IX V'
Kartagener syndrome
Osler Weber Rendu syndrome
Heberden nodes
Bernard Soulier dx
19. Small round eosinophilic masses found in dieing hepatocytes often containing chromatin remnants seen in viral hepatitis
Names of Vitamins
Kayser Fleischer ring
Hunter syndrome
Councilman body
20. Thrombotic occlusion of major hepatic veins - abnormal pain - jaundice - hepatomegaly - acites - liver failure - assoc with polycythemia vera - hepatocellular CA - and other common neoplasms - may occur as a complication of pregnancy
Raynaud phenomenon
Felty syndrome
Budd Chiari
Binswanger dx
21. Aka trisomy 18 - mental retardation - prominent occiput - micrognathia (small jaw) - low::set ears - rocker::bottom feet - finger deformities - congenital heart dx
C ANCA
Sipple syndrome
Reinke crystal
Edwards syndrome
22. Seen in hyperacute rejection - = acute inflammation - fibrinoid necrosis of small vessels - and extensive thrombosis
Wermer syndrome
Arthus reaction
Rotor syndrome
Bowenoid papulosis
23. Myc :: neuroblastoma amplicatiion correlates inversely with degree of differentiation
Orphan annie nuclei
Whipple triad
N
Heart failure cells
24. Binucleated or multinucleated giant cell seen in Hodgkin dx
Reed Sternburg cell
Hartnup dx
Tay Sachs dx
Bernard Soulier dx
25. Mucinous cell - characteristic of stomach CA met to ovary (krukenberg tumor)
Signet ring cell
BRCA2
Rotor syndrome
Burkitt lymphoma
26. Nystagmus - intention tremor - scanning speech - seen in MS
Mediterranean anemia or Cooley Anemia
Charcot triad
Cri du chat syndrome
Brutons Agammaglobulinemia
27. Associated with breast alone (isn't one of these associated with prostate? Check)
WT1 and WT2
Alport syndrome
Henoch Schonlein Purpura
BRCA2
28. Similar to paget breast - sometimes related to underlying adenoCA of sweat glands
Li Fraumeni syndrome
Donovan bodies
Hirano bodies
Paget dx of vulva
29. Mutation here causes pseudohypoparathyroidism
GNAS1
Von Gierke dx
Goodpasture syndrome
Bernard Soulier dx
30. Combination of hyperthyroidism - nodular goiter - absence of exophthalmos
Zenker diverticulum
Plummer dx
Hirschsprung dx
Alport syndrome
31. Intracytoplasmic proximal dentritic eosinophilic inclusions consisting of actin seen in Alzheimers
Hirano bodies
Nelson syndrome
Chromosome 10
Mediterranean anemia or Cooley Anemia
32. Burkitts c::myc is on 8 - IG heavy chain is on 14
Ras oncogenes
Hurler syndrome
Fabry dx
8:14
33. Area of focal interstitial myocardial inflammation characterized by fragmented collagen and fibrinoid material - by large cells (Anitschkow myocytes) and occasional multinucleated giant cells (Aschoff cells)
Fabry dx
Aschoff body
Signet ring cell
ret
34. Aka congenital megacolon - dilation of colon due to absence of ganglion cells
Von Hippel Lindau dx
Hirschsprung dx
Nelson syndrome
Osler Weber Rendu syndrome
35. Small round blue cell tumor of bone - long bones - kids - 11:22 transloc
Turner syndrome
Lambert Eaton syndrome
Ewing sarcoma
Raynaud disease
36. Transloc seen in ewing sarcoma
Crigler Najjar syndrome
Von Gierke dx
Bcl2
11:22
37. Aka osteitis deformans - increased osteoclastic and osteoblastic activity
Paget dx of bone
Von economo encephalitis
Ras oncogenes
WT1 and WT2
38. Esophageal diverticulum just above upper esoph sphincter
Whipple triad
Brenner tumor
Zenker diverticulum
Prader willi syndrome
39. Dysplastic cell seen in HPV
Koilocyte
Turner syndrome
Addison disease
Wegener granulomatosis
40. Hereditary nephritis associated with nerve deafness and ocular disorders - mutation in gene for the a5 chain of type IV collagen
Alport syndrome
Kawasaki dx
Whipple triad
Turcot syndrome
41. Deficient glucose -6- phosphatase - accumulation of glycogen in liver and kidney - hepatomegaly - hypoglycemia
Hutchinson freckle
Kimmelsteil Wilson dx
Cori dx
Von Gierke dx
42. Nuclei arranged in horseshoe - shaped pattern about periphery of cell - characteristic of but not specific for granulomatous TB (as opposed to a foreign body giant cell that has scattered nuclei)
Langhans giant cell
Clue cell
Brenner tumor
Kimmelsteil Wilson dx
43. Also seen in urine of MM - stacks of RBCs - will have high ESR
Rouleaux formation
Ras oncogenes
Waterhouse Friderichsen syndrome
Donovan bodies
44. Materal transmission del(15)(q11q13) - aka happy puppet syndrome - mental retardation - ataxia - seizures - inappropriate laughter
Councilman body
Angelman syndrome
Edwards syndrome
Bowenoid papulosis
45. Primary adrenal failure
Lynch syndrome
Hashimoto thyroiditis
Addison disease
ret PTC
46. Protooncogene mutated in medulary thyroid CA (MENII)
Wilms tumor
Waterhouse Friderichsen syndrome
ret
Stein Leventhal syndrome
47. Autosomal recessive - neutropenia - albinism - cranial and peripheral neuropathy - tendency to develop repeated infections - abnormal WBCs (abnormal mictotubul formation and large cytoplasmic granules = lysosomes)
Conn syndrome
Henoch Schonlein Purpura
Chediak Higashi syndrome
Reinke crystal
48. Malignant lymphoma with features resembling inflammatory disorder - young men - Reed Sternburg cells
Lesch Nyhan syndrome
Hodgkin dx
Sturge Weber syndrome
Burkitt lymphoma
49. Tumor suppressor common in familial polyposis coli and adenoCA of colon as well as other tumors
APC
Angelman syndrome
Tay Sachs dx
11:22
50. Impaired tubular reabsorption of tryptophan - pellagra::like manifestations
Brushfield spots
Addison disease
Gilbert syndrome
Hartnup dx