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Test your basic knowledge |
USMLE Brs Pathology Vocab
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Subjects
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health-sciences
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usmle
Instructions:
Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Tumor suppressor mutated in breast and ovary
BRCA1
WT1 and WT2
Klinefelter syndrome
Hodgkin dx
2. Binucleated or multinucleated giant cell seen in Hodgkin dx
Berger dx
Reed Sternburg cell
Heart failure cells
Negri bodies
3. Seen in granuloma inguinale - multiple organisms filling large histiocytes
WT1 and WT2
Gardner syndrome
Turner syndrome
Donovan bodies
4. Sphingomyelin containing phagocytes seen in Niemman::Pick dx in liver - spleen - lymph nodes and skin
Foamy histiocyte
Whipple dx
Prader willi syndrome
Pancoast tumor
5. Seen in urine of patients with multiple myeloma - Ig light chain either k or l
Fabry dx
Bense Jones protein
Pompe dx
Hfe gene
6. Ring of copper deposited around iris seen in Wilson
Plummer Vinson syndrome
Simmonds dx
Kayser Fleischer ring
8:14
7. Aka pulseless dx - inflammation and stenosis of medium and large sized arteries - often aortic arch thus aortic arch syndrome
Mediterranean anemia or Cooley Anemia
Takayasu arteritis
Von Recklinhousen dx
E4 allele of apoprotein E
8. Mesangial matrix material acculmulations seen in nodular glomerulosclerosis seen in diabetic nephropathy
McArdle syndrome
Kimmelstiel Wilson nodules
Arnold Chiari formation
Hutchinson freckle
9. Aka subcortical leukoencephalopathy - assoc with HTN - multiple lacunar infarcts and progressive demyelination in subcortical area
Addison disease
Brenner tumor
Koilocyte
Binswanger dx
10. Autosomal dominant - fatal - progressive degeneration of striatum and frontal cortex with neuronal depletion and gliosis
Heberden nodes
E4 allele of apoprotein E
Kartagener syndrome
Huntington dx
11. Polyostotic fibrous dysplasia - precocious puberty - caf
McCune Albright syndrome
Addison disease
Plummer Vinson syndrome
Beriberi
12. Deficient glucocerebrosidase - accumulation of glucocerebroside in cells of mononuclear phagocyte system 3 types ::
Letterer Siwe dx
Berger dx
Arthus reaction
Gaucher dx
13. Oncogenes that code for p21 proteins which are membrane signalers
Buerger dx
Bense Jones protein
Turner syndrome
Ras oncogenes
14. Aka IgA nephropathy - deposition of IgA in mesangium - benign recurrent hematuria in kids following infection
Raynaud disease
Berger dx
Waterhouse Friderichsen syndrome
ANAs in SLE
15. Aka allergic granulomatous angiitis - necrotizing vasculitis - variant of polyarteritis nodosa - involves pulmonary vasculature - peripheral eosinophilia - and asthma
Churg Strauss syndrome
Wermer syndrome
ANAs in SLE
Whipple dx
16. Aka superior sulcus tumor - seen in bronchogenic CA - often with Horner's
Rouleaux formation
11:22
Pancoast tumor
WT1 and WT2
17. Aka infantile progressive spinal muscular atrophy - autosomal recessive - LMN disease - infants
Werdnig Hoffman syndrome
Gilbert syndrome
Aschoff body
Wilms tumor
18. Located on xsome 6 - mutation here = hereditary hemochromatosis
9:22
Smudge cells
Bcl2
Hfe gene
19. Aka angiokeratoma corporis diffusum universal - deficient a::galactosidase A - accumulate ceramide trihexoside - skin lesions angiokeratomas - fever - burning pain in extremities - cardiovascular and cerebrovascular involvement - death as adult by re
E4 allele of apoprotein E
Berger dx
Fabry dx
Raynaud disease
20. Impaired tubular reabsorption of tryptophan - pellagra::like manifestations
Fanconi syndrome
Raynaud phenomenon
Hartnup dx
APC
21. Small round blue cell tumor of bone - long bones - kids - 11:22 transloc
Binswanger dx
C ANCA
Ewing sarcoma
Langhans giant cell
22. Associated with 90% cases of ankylosing spondylitis - common in rheumatoid arthritis
Kayser Fleischer ring
DiGeorge syndrome
HLA B27 antigen
Kartagener syndrome
23. Thyroid replacement by fibrous tissue - unkown origin - mimics
Mediterranean anemia or Cooley Anemia
Koilocyte
Reidel thyroiditis
Smudge cells
24. Adenomatous polyps with tumors of CNS
Huntington dx
Turcot syndrome
Reed Sternburg cell
Btk gene
25. Tennis racket shaped cytoplasmic inclusion seen in langerhans cells (so also seen in langerhan cell histiocytosis)
Reidel thyroiditis
Birbeck granule
Hutchinson freckle
Clue cell
26. B1 thiamine - B2 riboflavin - B3 niacin - B6 pyridoxine - B12 cobalamin - C ascorbic acid - D calciferol - E a::tocopherol
Lisch nodule
Waldenstrom Macroglobulinemia
Lynch syndrome
Names of Vitamins
27. Oligohydramnios causes fetus to be smashed
Potter sequence
Hodgkin dx
Guillain Barre syndrome
Addison disease
28. Appears as multiple wart - like lesions resembling condyloma accuminatum
Hutchinson freckle
Bowenoid papulosis
Stein Leventhal syndrome
Gerstmann Straussler
29. Autosomal dominant - numerous adenomatous polyps along with osteomas and soft tissue tumors
Prader willi syndrome
Gardner syndrome
Bernard Soulier dx
Takayasu arteritis
30. Intracytoplasmic inclusions seen in leydig cell tumors p283
ANAs in SLE
Reinke crystal
Brown tumor
Lisch nodule
31. Hemangioblastoma or cavernous hemangioma of cerebellum - brainstem or retina - adenomas - cysts in liver - kidney - pancreas - and other organs - increased renal cell CA - gene = short arm of chromosome 3
Krukenberg tumor
Von Hippel Lindau dx
Goodpasture syndrome
Rotor syndrome
32. Paraneoplastic synd looks like myasthenia gravis - often small cell lung CA
Bowenoid papulosis
Plummer dx
Alport syndrome
Lambert Eaton syndrome
33. Associated with papillary thyroid CA
Brown tumor
ret PTC
Hirano bodies
Fabry dx
34. Infectious disorder - caused postencephalitic parkinsonism
Foamy histiocyte
Chromosome 10
Von economo encephalitis
Berger dx
35. Philadelphia chromosome - CML bcr abl fusion c - abl on 9 - bcr on 22
Brushfield spots
9:22
Albers SCHonberg dx
14:18
36. Epithelial cells with eosinophilc granular cytoplasm seen in hashimoto
Hurthle cell
Prader willi syndrome
Lisch nodule
Takayasu arteritis
37. Defective cilia - sinusitis - bronchiectasis - situs inversus - sometimes hearing loss and male sterility
Kartagener syndrome
Foamy histiocyte
Bax
Smudge cells
38. 2/neu :: oncogene (aka c - erbB2) - in breast cancer = poor prognosis
Names of Vitamins
HER
Stein Leventhal syndrome
Bernard Soulier dx
39. DsDNA antibodies and Sm Smith antigen = highly specific for SLE
Gardner syndrome
Turcot syndrome
Graves dx
ANAs in SLE
40. Modest elevated serum unconj bilirubin - due to decreased uptake by liver cells and reduced activity of glucuronyl transferase
C ANCA
Denys Drash syndrome
Gilbert syndrome
Prader willi syndrome
41. Osteophytes at DIP joints
Heberden nodes
N
Meigs syndrome
Simmonds dx
42. Nystagmus - intention tremor - scanning speech - seen in MS
Charcot triad
Ferruginous body
FGFR3
Churg Strauss syndrome
43. Deficient hypoxanthine::guanine phosphoribosyltransferase (HGPRT) - low purine metabolism - high uric acid - thus gout - mental retardation - choreoathetosis - spasticity - self mutilation - aggressiveness
Wilms tumor
Lesch Nyhan syndrome
Marfan syndrome
Paget dx of vulva
44. Retinoblastoma on chromosome 13
Addison disease
Klinefelter syndrome
Rb gene
Reidel thyroiditis
45. Seen in papillary thyroid CA
Waterhouse Friderichsen syndrome
Rotor syndrome
Orphan annie nuclei
Albers SCHonberg dx
46. Osteophytes at PIP joints
Arthus reaction
Takayasu arteritis
Sipple syndrome
Bouchard nodes
47. Autosomal recessive - hepatitis - accumulation of copper due to transport problem - low ceruloplasmin seen - kayser fleischer rings in eyes
Graves dx
Shy Drager syndrome
14:18
Wilson dx
48. Renal tubular dysfunction - impaired reabsorption of glucose - amino acids - phosphate - and bicarb thus glycosuria - hyperphosphaturia - hypophosphatemia - aminoaciduria - systemic acidosis
Bcl2
Fanconi syndrome
Aschoff body
Hurler syndrome
49. Autosomal recessive - neutropenia - albinism - cranial and peripheral neuropathy - tendency to develop repeated infections - abnormal WBCs (abnormal mictotubul formation and large cytoplasmic granules = lysosomes)
Rb gene
Alport syndrome
Meigs syndrome
Chediak Higashi syndrome
50. Primary adrenal failure
Plummer Vinson syndrome
Councilman body
Addison disease
Gardner syndrome
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