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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Manifestation of lymphplasmocytic lymphoma - B cell neoplasm






2. Aka congenital megacolon - dilation of colon due to absence of ganglion cells






3. Burkitts c::myc is on 8 - IG heavy chain is on 14






4. Variant of rheumatoid arthritis - splenmegally - neutropenia - RA






5. Pituitary insufficiency post - partum - low TSH ACTH






6. At least 2 X and one Y - hypogonadism - tall - gynecomastia - low testosterone - high pituitary gonadotropins - infertility -






7. Abnormal WT 1 gene - intersexual disorders - nephropathy - wilms tumor






8. Area of focal interstitial myocardial inflammation characterized by fragmented collagen and fibrinoid material - by large cells (Anitschkow myocytes) and occasional multinucleated giant cells (Aschoff cells)






9. Esophageal diverticulum just above upper esoph sphincter






10. Seen in insulinoma - episodic hyperinsulinemia and hypoglycemia - CNS dysfunction - reversal of CNS probs with administration of glucose






11. Autosomal dominant - numerous adenomatous polyps along with osteomas and soft tissue tumors






12. Triad of ovarian fibroma - ascites - hydrothorax






13. Also seen in urine of MM - stacks of RBCs - will have high ESR






14. Seen in urine of patients with multiple myeloma - Ig light chain either k or l






15. Ovarian tumor resembling bladder transitional epith






16. Seen in papillary thyroid CA






17. Non::neoplastic tumor like masses - fibrous replacement of resorbed bone






18. Binucleated or multinucleated giant cell seen in Hodgkin dx






19. Vasosmasm of small vessels - most often in fingers - seen with autoimmune dx like SLE - scleroderma and others (R in CREST) - recurrent vasospasm - always secondary to underlying disorder






20. Protooncogene mutated in medulary thyroid CA (MENII)






21. Autosomal recessive - hepatitis - accumulation of copper due to transport problem - low ceruloplasmin seen - kayser fleischer rings in eyes






22. Sphingomyelin containing phagocytes seen in Niemman::Pick dx in liver - spleen - lymph nodes and skin






23. Materal transmission del(15)(q11q13) - aka happy puppet syndrome - mental retardation - ataxia - seizures - inappropriate laughter






24. Aka pulseless dx - inflammation and stenosis of medium and large sized arteries - often aortic arch thus aortic arch syndrome






25. Epithelial cells with eosinophilc granular cytoplasm seen in hashimoto






26. Dysplastic cell seen in HPV






27. DsDNA antibodies and Sm Smith antigen = highly specific for SLE






28. Primary aldosteronism






29. Hereditary nonpolyposis colon cancer - DNA repair genes messed up






30. Aka angiokeratoma corporis diffusum universal - deficient a::galactosidase A - accumulate ceramide trihexoside - skin lesions angiokeratomas - fever - burning pain in extremities - cardiovascular and cerebrovascular involvement - death as adult by re






31. Intra::alveolar hemosiderin - laden macrophages caused by RBCs from capillary rupture 2* to pulmonary HTN






32. Intracytoplasmic inclusions seen in leydig cell tumors p283






33. Mucinous cell - characteristic of stomach CA met to ovary (krukenberg tumor)






34. Osteophytes at PIP joints






35. Minute neutrophilic abscesses found within parakeratotic stratum corneum in psoriasis






36. Nuclei arranged in horseshoe - shaped pattern about periphery of cell - characteristic of but not specific for granulomatous TB (as opposed to a foreign body giant cell that has scattered nuclei)






37. Paracentric inversion or translocation with 17 associated with papillary thyroid CA






38. Autoimmune thyroiditis - hyperthyroid - exophthalmos - increased in HLA DR3 and HLA B8 pos people






39. Tennis racket shaped cytoplasmic inclusion seen in langerhans cells (so also seen in langerhan cell histiocytosis)






40. Follicular lymphoma IG heavy chain on 14 - bcl -2 oncogene on 18






41. Iron deficient anemia associated with upper::esophageal web






42. Deficient hypoxanthine::guanine phosphoribosyltransferase (HGPRT) - low purine metabolism - high uric acid - thus gout - mental retardation - choreoathetosis - spasticity - self mutilation - aggressiveness






43. Combination of hyperthyroidism - nodular goiter - absence of exophthalmos






44. 2/neu :: oncogene (aka c - erbB2) - in breast cancer = poor prognosis






45. Malabsorption syndrome - Tropheryma wippelii bacilli - small intestine commonly affected - arthralgias - cardiac - and neuro symptoms






46. Modest elevated serum unconj bilirubin - due to decreased uptake by liver cells and reduced activity of glucuronyl transferase






47. Associated with Wegener granulomatosis






48. This comes in a wet variety and a dry one - they are both Vit B1 thiamine deficiency






49. Autosomal recessive - unusually large platelets - lack of 'GPIb IX V'






50. = MEN2a