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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Intra::alveolar hemosiderin - laden macrophages caused by RBCs from capillary rupture 2* to pulmonary HTN






2. Aka angiokeratoma corporis diffusum universal - deficient a::galactosidase A - accumulate ceramide trihexoside - skin lesions angiokeratomas - fever - burning pain in extremities - cardiovascular and cerebrovascular involvement - death as adult by re






3. Peripheral neuropathy - atrophy of muscles - wet - high output cardiac failure - DCM - AV shunting - hypervolemia






4. Deficient muscle phosphorylase - glycogen in skeletal muscle - cramps with exertion






5. Oncogenes that code for p21 proteins which are membrane signalers






6. Deficient a1 -4 glucosidase - accumulation of glycogen in liver - heart - skeletal muscle - cardiomegaly - muscle hypotonia - spelnomegaly - intractable hypoglycemia - death from cardiorespiratory failure before age 3






7. Development of large pituitary adenomas following bilat adrenalectomy






8. Vaginal epithelial cell with stippled appearance due to adherent coccobacilli






9. Autosomal recessive - hepatitis - accumulation of copper due to transport problem - low ceruloplasmin seen - kayser fleischer rings in eyes






10. Variant of rheumatoid arthritis - aka juvenile rheumatoid arthritis






11. B1 thiamine - B2 riboflavin - B3 niacin - B6 pyridoxine - B12 cobalamin - C ascorbic acid - D calciferol - E a::tocopherol






12. Similar to paget breast - sometimes related to underlying adenoCA of sweat glands






13. Tumor suppressor mutated in Von Recklinhousen






14. Aka pituitary cachexia - generalized panhypopituitarism






15. Nystagmus - intention tremor - scanning speech - seen in MS






16. Triad of ovarian fibroma - ascites - hydrothorax






17. Non::neoplastic tumor like masses - fibrous replacement of resorbed bone






18. Seen in urine of patients with multiple myeloma - Ig light chain either k or l






19. Thyroid replacement by fibrous tissue - unkown origin - mimics






20. Subcutaneous fibrosis of dorsum of penis






21. Aggressive B- cell lymphoma - EBV - starry sky appearance - c myc






22. Deficient sphingomyelinase - accumulation of sphingomyelin in phagocytes - foamy histiocytes in liver - spleen - lymph nodes - skin - hepatosplenomegaly - anemia fever - occasional neuro degeneration - half have cherry red spot macula






23. Retinoblastoma on chromosome 13






24. Metastatic stomach CA to ovary






25. Protooncogene mutated in medulary thyroid CA (MENII)






26. X linked - absence of plasma cells and serum immunoglobulins - cell mediated immunity still ok - no germinal centers - recurrent bacterial infections - resistances to fungal and viral still - btk gene defect






27. Aka mucocutaneous lymph node syndrome - acute self - limited - infants and young kids - acute necrotizing vasculitis of small and medium vessels - fever hemorrhagic edema of conjunctivae - lips and oral mucosa - and cervical LAD - can cause coronary






28. Defective in x- linked brutons agammaglobulinemia - B- cell tyrosine kinase






29. Vasosmasm of small vessels - most often in fingers - seen with autoimmune dx like SLE - scleroderma and others (R in CREST) - recurrent vasospasm - always secondary to underlying disorder






30. Seen in granuloma inguinale - multiple organisms filling large histiocytes






31. B Thalassemia major






32. Autoimmune hypothyroid - hurthle cells common






33. Aka osteitis deformans - increased osteoclastic and osteoblastic activity






34. Gene mutated in achondroplasia (most common form of dwarfism) - located at 4p16.3






35. Myc :: neuroblastoma amplicatiion correlates inversely with degree of differentiation






36. Sphingomyelin containing phagocytes seen in Niemman::Pick dx in liver - spleen - lymph nodes and skin






37. Aka lentigo maligna - precursor to lentigo maligna melanoma






38. Modest elevated serum unconj bilirubin - due to decreased uptake by liver cells and reduced activity of glucuronyl transferase






39. This comes in a wet variety and a dry one - they are both Vit B1 thiamine deficiency






40. Deficient glucose -6- phosphatase - accumulation of glycogen in liver and kidney - hepatomegaly - hypoglycemia






41. Malabsorption syndrome - Tropheryma wippelii bacilli - small intestine commonly affected - arthralgias - cardiac - and neuro symptoms






42. Aka trisomy 13 - mental retardation - microcephaly - micropthalmia - brain abnormalities - cleft lip/palate - polydactyly - rockerbottom feet - congenital heart dx






43. Asbestosis - yellow - brown - rod shaped body with clubbed ends - stain with Prussian blue






44. Tennis racket shaped cytoplasmic inclusion seen in langerhans cells (so also seen in langerhan cell histiocytosis)






45. Similar to Hurler - deficient L iduronosulfate sulfatase - accumulations of heparin sulfate and dermatan sulfate - hepatospenomegaly - micrognathia - retinal degeneration - joint stiffness - mental retardation - cardiac lesions






46. Ovarian tumor resembling bladder transitional epith






47. Esophageal diverticulum just above upper esoph sphincter






48. Seen in CLL - leukemic B- cells that are fragile






49. Combination of hyperthyroidism - nodular goiter - absence of exophthalmos






50. 2/neu :: oncogene (aka c - erbB2) - in breast cancer = poor prognosis