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Test your basic knowledge |
USMLE Brs Pathology Vocab
Start Test
Study First
Subjects
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health-sciences
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usmle
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Hereditary nephritis associated with nerve deafness and ocular disorders - mutation in gene for the a5 chain of type IV collagen
Beriberi
Smudge cells
Alport syndrome
Brenner tumor
2. Iron deficient anemia associated with upper::esophageal web
Sipple syndrome
ret PTC
Plummer Vinson syndrome
Fabry dx
3. Autosomal dominant - numerous adenomatous polyps along with osteomas and soft tissue tumors
Signet ring cell
Codman triangle
Gardner syndrome
Shy Drager syndrome
4. Area of focal interstitial myocardial inflammation characterized by fragmented collagen and fibrinoid material - by large cells (Anitschkow myocytes) and occasional multinucleated giant cells (Aschoff cells)
Aschoff body
Takayasu arteritis
Peyronie dx
Shy Drager syndrome
5. Esophageal diverticulum just above upper esoph sphincter
Zenker diverticulum
Hirano bodies
Paget dx of vulva
Ewing sarcoma
6. This comes in a wet variety and a dry one - they are both Vit B1 thiamine deficiency
Beriberi
Koilocyte
11:22
Lesch Nyhan syndrome
7. Malignant lymphoma with features resembling inflammatory disorder - young men - Reed Sternburg cells
FGFR3
McCune Albright syndrome
15:17
Hodgkin dx
8. Aka thromboangiitis obliterans - acute inflame of small and med arteries of extremities - extending to adjacent veins and nerves - young jewish men - painful ischemic dx - worse with smoking
Donovan bodies
Buerger dx
Brutons Agammaglobulinemia
Brown tumor
9. Acute inflammatory demyelinating dx primarily involving peripheral nerves
Edwards syndrome
Kartagener syndrome
Guillain Barre syndrome
Hunter syndrome
10. Subcutaneous fibrosis of dorsum of penis
Wermer syndrome
Budd Chiari
Peyronie dx
Bouchard nodes
11. Hemihypertrophy - macroglossia - organomegaly - neonatal hypoglycemia - various embryonal tumors - deleted WT 2 gene
Beckwith Weidemann syndrome
Hirano bodies
GNAS1
Arthus reaction
12. Catastrophic adrenal insuff and vascular collapse - hemorrhagic necrosis of adrenal cortex
Waterhouse Friderichsen syndrome
HER
Bernard Soulier dx
Negri bodies
13. Vasosmasm of small vessels - most often in fingers - seen with autoimmune dx like SLE - scleroderma and others (R in CREST) - recurrent vasospasm - always secondary to underlying disorder
Li Fraumeni syndrome
Dubin Johnson syndrome
Raynaud phenomenon
Starry sky appearance
14. Appears as multiple wart - like lesions resembling condyloma accuminatum
Bowenoid papulosis
Raynaud phenomenon
Li Fraumeni syndrome
Ferruginous body
15. Aka superior sulcus tumor - seen in bronchogenic CA - often with Horner's
Sturge Weber syndrome
Shy Drager syndrome
Pancoast tumor
Negri bodies
16. Autosomal recessive - unusually large platelets - lack of 'GPIb IX V'
Still disease
Wermer syndrome
Patau syndrome
Bernard Soulier dx
17. Aka lentigo maligna - precursor to lentigo maligna melanoma
15:17
Rouleaux formation
Hutchinson freckle
Hurler syndrome
18. Aka pulseless dx - inflammation and stenosis of medium and large sized arteries - often aortic arch thus aortic arch syndrome
Wilms tumor
Takayasu arteritis
Koilocyte
Still disease
19. Urethritis - conjunctivitis - arthritis - associated with venereal or intestinal infection
Foamy histiocyte
Pompe dx
Reiter syndrome
8:14
20. Aka allergic granulomatous angiitis - necrotizing vasculitis - variant of polyarteritis nodosa - involves pulmonary vasculature - peripheral eosinophilia - and asthma
Waldenstrom Macroglobulinemia
Churg Strauss syndrome
Paget dx of breast
Orphan annie nuclei
21. Lots of tumors - breast CA - soft tissue sarc - brain tumors - leukemias - has loss of p53 tumor suppressor gene
Signet ring cell
ret
Wermer syndrome
Li Fraumeni syndrome
22. Polyostotic fibrous dysplasia - precocious puberty - caf
McCune Albright syndrome
Pompe dx
Arnold Chiari formation
Bense Jones protein
23. Gene product facilitates apoptosis - decreases bcl::2 and increases Bax
Pompe dx
Hand Schuller Christian dx
p53
11:22
24. Acute promyelocytic leukemia PML gene on 15 and RARa on 17
Klinefelter syndrome
15:17
Kawasaki dx
Werdnig Hoffman syndrome
25. Aka hereditary hemorrhagic telangectasia - telangectasias in skin and mucous membranes - epistaxis - GI bleeds
Whipple dx
Raynaud phenomenon
Osler Weber Rendu syndrome
Nelson syndrome
26. Similar to paget breast - sometimes related to underlying adenoCA of sweat glands
Beriberi
Paget dx of vulva
Gaucher dx
McCune Albright syndrome
27. Binucleated or multinucleated giant cell seen in Hodgkin dx
McCune Albright syndrome
Reed Sternburg cell
Ewing sarcoma
Kayser Fleischer ring
28. Deficient fibrillin (constituent of microfibrils) - arachnodactyly - ectopia lentis - aortic aneurysm - mitral valve prolapsed
Alport syndrome
Marfan syndrome
Aschoff body
Foamy histiocyte
29. Radiologic appearance of periostium in bone tumors
15:17
Paget dx of bone
Codman triangle
Gilbert syndrome
30. Oligohydramnios causes fetus to be smashed
BRCA2
Munro abscesses
Wermer syndrome
Potter sequence
31. Autosomal recessive - conj hyperbilirubinemia - defect in bili transport - black color to liver
Hirschsprung dx
Koilocyte
Dubin Johnson syndrome
Letterer Siwe dx
32. 2/neu :: oncogene (aka c - erbB2) - in breast cancer = poor prognosis
HER
Beckwith Weidemann syndrome
Lesch Nyhan syndrome
Wegener granulomatosis
33. Philadelphia chromosome - CML bcr abl fusion c - abl on 9 - bcr on 22
9:22
15:17
Pompe dx
Potter sequence
34. Vaginal epithelial cell with stippled appearance due to adherent coccobacilli
Clue cell
NF1
Paget dx of bone
Whipple dx
35. Ring of copper deposited around iris seen in Wilson
Virchow node
Cori dx
Mediterranean anemia or Cooley Anemia
Kayser Fleischer ring
36. Adenomatous polyps with tumors of CNS
Brutons Agammaglobulinemia
Goodpasture syndrome
Turcot syndrome
Raynaud disease
37. Associated with Wegener granulomatosis
C ANCA
Clue cell
Hashimoto thyroiditis
DiGeorge syndrome
38. Aka osteopetrosis - marble bone dx - dense skeleton - failure of osteoclastic activity
Albers SCHonberg dx
ANAs in SLE
Heart failure cells
Reiter syndrome
39. Gene product inhibits apoptosis
Pancoast tumor
Beckwith Weidemann syndrome
15:17
Bcl2
40. Deficient glucose -6- phosphatase - accumulation of glycogen in liver and kidney - hepatomegaly - hypoglycemia
Edwards syndrome
Brenner tumor
Hirschsprung dx
Von Gierke dx
41. Hemorrhagic urticaria of extensor surgaces of arms - legs - and buttocks - with fever - arthralgias - and GI renal involvement similar to IgA nephropathy - associated with URIs
Bense Jones protein
Henoch Schonlein Purpura
Virchow node
WT1 and WT2
42. Aneurysm at small artery bifurcations
Lisch nodule
Huntington dx
Charcot Bouchard aneurysm
Starry sky appearance
43. Similar to Dubin Johnson with no black liver
Rotor syndrome
Call Exner bodies
Wiskott Aldrich syndrome
WT1 and WT2
44. Nystagmus - intention tremor - scanning speech - seen in MS
Foamy histiocyte
Lesch Nyhan syndrome
Charcot triad
Hurthle cell
45. Seen in Down synd - small white spots on periphery of iris
Foamy histiocyte
Donovan bodies
Raynaud disease
Brushfield spots
46. Autoimmune hypothyroid - hurthle cells common
Stein Leventhal syndrome
Langhans giant cell
Brutons Agammaglobulinemia
Hashimoto thyroiditis
47. Aka mucocutaneous lymph node syndrome - acute self - limited - infants and young kids - acute necrotizing vasculitis of small and medium vessels - fever hemorrhagic edema of conjunctivae - lips and oral mucosa - and cervical LAD - can cause coronary
Peutz Jeghers syndrome
NF1
GNAS1
Kawasaki dx
48. Thyroid replacement by fibrous tissue - unkown origin - mimics
Reidel thyroiditis
WT1 and WT2
Osler Weber Rendu syndrome
Peyronie dx
49. Single erythematous plaque on shaft of penis or scrotum
Budd Chiari
Bowen dx
Kimmelsteil Wilson dx
Gardner syndrome
50. Infectious disorder - caused postencephalitic parkinsonism
Hurthle cell
Kayser Fleischer ring
Budd Chiari
Von economo encephalitis