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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Severe unconj hyperbilirubinemia due to deficient glucuronyl transferase






2. Variant of rheumatoid arthritis - splenmegally - neutropenia - RA






3. Burkitts c::myc is on 8 - IG heavy chain is on 14






4. Aka acute disseminated langerhans cell histiocytosis - aggressive - usually fatal - kids hepatosplenomegaly - LAD - pancytopenia - pulmonary involvement - recurrent infections






5. Hereditary nonpolyposis colon cancer - DNA repair genes messed up






6. Metastatic stomach CA to ovary






7. Associated with breast alone (isn't one of these associated with prostate? Check)






8. Infectious disorder - caused postencephalitic parkinsonism






9. Pigmented iris hamartoma seen in neurofibromatosis






10. Deficient a1 -4 glucosidase - accumulation of glycogen in liver - heart - skeletal muscle - cardiomegaly - muscle hypotonia - spelnomegaly - intractable hypoglycemia - death from cardiorespiratory failure before age 3






11. Aka hereditary hemorrhagic telangectasia - telangectasias in skin and mucous membranes - epistaxis - GI bleeds






12. Tumor suppressor mutated in Von Recklinhousen






13. Deficient sphingomyelinase - accumulation of sphingomyelin in phagocytes - foamy histiocytes in liver - spleen - lymph nodes - skin - hepatosplenomegaly - anemia fever - occasional neuro degeneration - half have cherry red spot macula






14. On lymph node biopsy - seen with Burkitt lymphoma






15. Aka lentigo maligna - precursor to lentigo maligna melanoma






16. Gene product facilitates apoptosis






17. Small round eosinophilic masses found in dieing hepatocytes often containing chromatin remnants seen in viral hepatitis






18. Mesangial matrix material acculmulations seen in nodular glomerulosclerosis seen in diabetic nephropathy






19. Chromosome 19 - allele common in alzheimers






20. Primary aldosteronism






21. Modest elevated serum unconj bilirubin - due to decreased uptake by liver cells and reduced activity of glucuronyl transferase






22. Vaginal epithelial cell with stippled appearance due to adherent coccobacilli






23. Aka velocardiofacial syndrome and CATCH 22 syndrome - micro deletion of 22q11 - Cardiac abnormalities - Abnormal facies - T cell deficit due to thymic hypoplasia - Cleft palate - Hypocalcemia due to hypoparathyroidism - from poor development of 3rd a






24. B Thalassemia major






25. Also seen in urine of MM - stacks of RBCs - will have high ESR






26. Appears as multiple wart - like lesions resembling condyloma accuminatum






27. Radiologic appearance of periostium in bone tumors






28. Aneurysm at small artery bifurcations






29. Intra::alveolar hemosiderin - laden macrophages caused by RBCs from capillary rupture 2* to pulmonary HTN






30. Paracentric inversion or translocation with 17 associated with papillary thyroid CA






31. DsDNA antibodies and Sm Smith antigen = highly specific for SLE






32. Deficient fibrillin (constituent of microfibrils) - arachnodactyly - ectopia lentis - aortic aneurysm - mitral valve prolapsed






33. Hemihypertrophy - macroglossia - organomegaly - neonatal hypoglycemia - various embryonal tumors - deleted WT 2 gene






34. Sphingomyelin containing phagocytes seen in Niemman::Pick dx in liver - spleen - lymph nodes and skin






35. Deficient glucose -6- phosphatase - accumulation of glycogen in liver and kidney - hepatomegaly - hypoglycemia






36. Variant of rheumatoid arthritis - aka juvenile rheumatoid arthritis






37. Aggressive B- cell lymphoma - EBV - starry sky appearance - c myc






38. X linked - aka immunodeficiency with thrombocytopenia and eczema - total immunoglobulins often normal - recurrent infections






39. Aka trisomy 13 - mental retardation - microcephaly - micropthalmia - brain abnormalities - cleft lip/palate - polydactyly - rockerbottom feet - congenital heart dx






40. Different in that it is the primary disorder - recurrent vasospasm of small arteries and venules - pallor - cyanosis - fingers and toes - young healthy women






41. Aka allergic granulomatous angiitis - necrotizing vasculitis - variant of polyarteritis nodosa - involves pulmonary vasculature - peripheral eosinophilia - and asthma






42. Primary adrenal failure






43. Aka pituitary cachexia - generalized panhypopituitarism






44. Aka pulseless dx - inflammation and stenosis of medium and large sized arteries - often aortic arch thus aortic arch syndrome






45. Similar to paget breast - sometimes related to underlying adenoCA of sweat glands






46. Epithelial cells with eosinophilc granular cytoplasm seen in hashimoto






47. Esophageal diverticulum just above upper esoph sphincter






48. Located on xsome 6 - mutation here = hereditary hemochromatosis






49. Malignant lymphoma with features resembling inflammatory disorder - young men - Reed Sternburg cells






50. Hemorrhagic urticaria of extensor surgaces of arms - legs - and buttocks - with fever - arthralgias - and GI renal involvement similar to IgA nephropathy - associated with URIs