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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Acute promyelocytic leukemia PML gene on 15 and RARa on 17






2. Autosomal dominant - fatal - progressive degeneration of striatum and frontal cortex with neuronal depletion and gliosis






3. Catastrophic adrenal insuff and vascular collapse - hemorrhagic necrosis of adrenal cortex






4. Mutation here causes pseudohypoparathyroidism






5. Malignant lymphoma with features resembling inflammatory disorder - young men - Reed Sternburg cells






6. Esophageal diverticulum just above upper esoph sphincter






7. X linked - absence of plasma cells and serum immunoglobulins - cell mediated immunity still ok - no germinal centers - recurrent bacterial infections - resistances to fungal and viral still - btk gene defect






8. Seen in Down synd - small white spots on periphery of iris






9. Ovarian tumor resembling bladder transitional epith






10. Subcutaneous fibrosis of dorsum of penis






11. Manifestation of lymphplasmocytic lymphoma - B cell neoplasm






12. Vasosmasm of small vessels - most often in fingers - seen with autoimmune dx like SLE - scleroderma and others (R in CREST) - recurrent vasospasm - always secondary to underlying disorder






13. Intracytoplasmic proximal dentritic eosinophilic inclusions consisting of actin seen in Alzheimers






14. Asbestosis - yellow - brown - rod shaped body with clubbed ends - stain with Prussian blue






15. Seen in insulinoma - episodic hyperinsulinemia and hypoglycemia - CNS dysfunction - reversal of CNS probs with administration of glucose






16. Thrombotic occlusion of major hepatic veins - abnormal pain - jaundice - hepatomegaly - acites - liver failure - assoc with polycythemia vera - hepatocellular CA - and other common neoplasms - may occur as a complication of pregnancy






17. Pigmented iris hamartoma seen in neurofibromatosis






18. Hemihypertrophy - macroglossia - organomegaly - neonatal hypoglycemia - various embryonal tumors - deleted WT 2 gene






19. Hemangioblastoma or cavernous hemangioma of cerebellum - brainstem or retina - adenomas - cysts in liver - kidney - pancreas - and other organs - increased renal cell CA - gene = short arm of chromosome 3






20. B1 thiamine - B2 riboflavin - B3 niacin - B6 pyridoxine - B12 cobalamin - C ascorbic acid - D calciferol - E a::tocopherol






21. 2/neu :: oncogene (aka c - erbB2) - in breast cancer = poor prognosis






22. Retinoblastoma on chromosome 13






23. Occurs in SLE - small vegitations on either or both surfaces of valves






24. Associated with papillary thyroid CA






25. Deficient hexosaminidase A - GM2 ganglioside accumulation - especially in neurons - CNS degeneration - mental/motor deterioration - blindness - cherry red spot on macula - death by 4 years of age






26. Tumor suppressor mutated in Von Recklinhousen






27. Autoimmune hypothyroid - hurthle cells common






28. Thyroid replacement by fibrous tissue - unkown origin - mimics






29. Tennis racket shaped cytoplasmic inclusion seen in langerhans cells (so also seen in langerhan cell histiocytosis)






30. Aggressive B- cell lymphoma - EBV - starry sky appearance - c myc






31. Urethritis - conjunctivitis - arthritis - associated with venereal or intestinal infection






32. Autosomal recessive - hepatitis - accumulation of copper due to transport problem - low ceruloplasmin seen - kayser fleischer rings in eyes






33. Ring of copper deposited around iris seen in Wilson






34. Non::neoplastic tumor like masses - fibrous replacement of resorbed bone






35. Hereditary nephritis associated with nerve deafness and ocular disorders - mutation in gene for the a5 chain of type IV collagen






36. Aka osteopetrosis - marble bone dx - dense skeleton - failure of osteoclastic activity






37. Variant of rheumatoid arthritis - aka juvenile rheumatoid arthritis






38. = MEN2a






39. Seen in granuloma inguinale - multiple organisms filling large histiocytes






40. Combination of hyperthyroidism - nodular goiter - absence of exophthalmos






41. At least 2 X and one Y - hypogonadism - tall - gynecomastia - low testosterone - high pituitary gonadotropins - infertility -






42. Seen in papillary thyroid CA






43. Mutation = paroxysmal nocturnal hemoglobinuria






44. Minute neutrophilic abscesses found within parakeratotic stratum corneum in psoriasis






45. Oncogenes that code for p21 proteins which are membrane signalers






46. Dysplastic cell seen in HPV






47. On lymph node biopsy - seen with Burkitt lymphoma






48. Diffuse nodular diabetic glomerulosclerosis






49. Downward displacement of cerebellar tonsils and medulla through foramen magnum






50. Radiologic appearance of periostium in bone tumors