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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Osteophytes at PIP joints






2. Urethritis - conjunctivitis - arthritis - associated with venereal or intestinal infection






3. 2/neu :: oncogene (aka c - erbB2) - in breast cancer = poor prognosis






4. Paraneoplastic synd looks like myasthenia gravis - often small cell lung CA






5. Impaired tubular reabsorption of tryptophan - pellagra::like manifestations






6. Aka osteopetrosis - marble bone dx - dense skeleton - failure of osteoclastic activity






7. Mesangial matrix material acculmulations seen in nodular glomerulosclerosis seen in diabetic nephropathy






8. Autosomal recessive - neutropenia - albinism - cranial and peripheral neuropathy - tendency to develop repeated infections - abnormal WBCs (abnormal mictotubul formation and large cytoplasmic granules = lysosomes)






9. Associated with papillary thyroid CA






10. Aka thromboangiitis obliterans - acute inflame of small and med arteries of extremities - extending to adjacent veins and nerves - young jewish men - painful ischemic dx - worse with smoking






11. At least 2 X and one Y - hypogonadism - tall - gynecomastia - low testosterone - high pituitary gonadotropins - infertility -






12. = MEN1






13. Autosomal recessive - conj hyperbilirubinemia - defect in bili transport - black color to liver






14. Intracytoplasmic inclusions seen in leydig cell tumors p283






15. Eczematoid lesion of nipple areola - large cells with clear 'halo like' area - invade epidermis - underlying ductal CA






16. Small follicles filled with eosinophilic secretion - diagnostic feature of granulose cell tumor






17. Deficient hexosaminidase A - GM2 ganglioside accumulation - especially in neurons - CNS degeneration - mental/motor deterioration - blindness - cherry red spot on macula - death by 4 years of age






18. Lots of tumors - breast CA - soft tissue sarc - brain tumors - leukemias - has loss of p53 tumor suppressor gene






19. Infectious disorder - caused postencephalitic parkinsonism






20. Gene product facilitates apoptosis






21. Deficient muscle phosphorylase - glycogen in skeletal muscle - cramps with exertion






22. Acute promyelocytic leukemia PML gene on 15 and RARa on 17






23. Seen in granuloma inguinale - multiple organisms filling large histiocytes






24. Paternal transmission del (15)(q11q13) - hypogonad - hypotonia - mental retardation - behavior probs - uncrontrolled appetite






25. Retinoblastoma on chromosome 13






26. Catastrophic adrenal insuff and vascular collapse - hemorrhagic necrosis of adrenal cortex






27. Associated with breast alone (isn't one of these associated with prostate? Check)






28. Malabsorption syndrome - Tropheryma wippelii bacilli - small intestine commonly affected - arthralgias - cardiac - and neuro symptoms






29. Aka antiglomerular basement membrane dx - antibodies against alveolar and glomerular basement membranes - linear immunoflorescence






30. Deficient sphingomyelinase - accumulation of sphingomyelin in phagocytes - foamy histiocytes in liver - spleen - lymph nodes - skin - hepatosplenomegaly - anemia fever - occasional neuro degeneration - half have cherry red spot macula






31. Tumor suppressor common in familial polyposis coli and adenoCA of colon as well as other tumors






32. Small round blue cell tumor of bone - long bones - kids - 11:22 transloc






33. Autosomal dominant - numerous adenomatous polyps along with osteomas and soft tissue tumors






34. Vasosmasm of small vessels - most often in fingers - seen with autoimmune dx like SLE - scleroderma and others (R in CREST) - recurrent vasospasm - always secondary to underlying disorder






35. Aspirin toxicity seen in kids after acute febrile viral dx - microvesicular fatty change in liver and encephalopathy






36. Philadelphia chromosome - CML bcr abl fusion c - abl on 9 - bcr on 22






37. Thiamine deficiency - cerebral dysfunction - aka alcoholic encephalopathy - hemorrhagic lesions in the mamillary bodies - confusion - ataxia - ophthalmoplegia - and memory loss plus confabulation p 105 and p115






38. Mucopolysaccharidosis - deficient a L iduronidase - accumulations of heparin sulfate and dermatan sulfate in heart - brain - liver - and other organs - progressive - hepatosplenomagaly - dwarfism - gargoyle - like facies - stubby fingers - corneal cl






39. Aka mucocutaneous lymph node syndrome - acute self - limited - infants and young kids - acute necrotizing vasculitis of small and medium vessels - fever hemorrhagic edema of conjunctivae - lips and oral mucosa - and cervical LAD - can cause coronary






40. Mucinous cell - characteristic of stomach CA met to ovary (krukenberg tumor)






41. 45 XO - female hypogonadism - hypothyroid - short - webbed neck - 1* amenorrhea p52






42. Vaginal epithelial cell with stippled appearance due to adherent coccobacilli






43. Esophageal diverticulum just above upper esoph sphincter






44. Deficient debranching enzyme amylo -1 -6- glucosidase - glycogen in liver - heart - skeletal muscle - stunted growth - hepatomegaly - hypoglycemia






45. Mutation here causes pseudohypoparathyroidism






46. Combination of hyperthyroidism - nodular goiter - absence of exophthalmos






47. Superclavicular lymph node identifying metastatic stomach CA






48. Hereditary nonpolyposis colon cancer - DNA repair genes messed up






49. B1 thiamine - B2 riboflavin - B3 niacin - B6 pyridoxine - B12 cobalamin - C ascorbic acid - D calciferol - E a::tocopherol






50. Gene mutated in achondroplasia (most common form of dwarfism) - located at 4p16.3






Can you answer 50 questions in 15 minutes?



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