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Test your basic knowledge |
USMLE Brs Pathology Vocab
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Subjects
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health-sciences
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usmle
Instructions:
Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Aka pulseless dx - inflammation and stenosis of medium and large sized arteries - often aortic arch thus aortic arch syndrome
Whipple triad
Tay Sachs dx
Takayasu arteritis
Plummer dx
2. Also seen in urine of MM - stacks of RBCs - will have high ESR
Rouleaux formation
Kawasaki dx
BRCA1
Letterer Siwe dx
3. Aka osteopetrosis - marble bone dx - dense skeleton - failure of osteoclastic activity
Guillain Barre syndrome
McArdle syndrome
Alport syndrome
Albers SCHonberg dx
4. Autosomal recessive - conj hyperbilirubinemia - defect in bili transport - black color to liver
Charcot triad
Dubin Johnson syndrome
Denys Drash syndrome
Lynch syndrome
5. Small follicles filled with eosinophilic secretion - diagnostic feature of granulose cell tumor
ret PTC
Albers SCHonberg dx
Call Exner bodies
Rotor syndrome
6. Seen in hyperacute rejection - = acute inflammation - fibrinoid necrosis of small vessels - and extensive thrombosis
Tay Sachs dx
Alport syndrome
Arthus reaction
Gerstmann Straussler
7. Parkinsonism with autonomic dysfunction and orthostatic hypotension
Whipple dx
Shy Drager syndrome
Bowen dx
Orphan annie nuclei
8. Hereditary nonpolyposis colon cancer - DNA repair genes messed up
Bernard Soulier dx
Werdnig Hoffman syndrome
Lynch syndrome
Stein Leventhal syndrome
9. Hereditary nephritis associated with nerve deafness and ocular disorders - mutation in gene for the a5 chain of type IV collagen
Waldenstrom Macroglobulinemia
Niemann Pick dx
Koilocyte
Alport syndrome
10. Lots of tumors - breast CA - soft tissue sarc - brain tumors - leukemias - has loss of p53 tumor suppressor gene
Li Fraumeni syndrome
WT1 and WT2
Wermer syndrome
Pancoast tumor
11. Similar to Dubin Johnson with no black liver
Waldenstrom Macroglobulinemia
Rotor syndrome
Hurthle cell
FGFR3
12. Seen in papillary thyroid CA
Plummer Vinson syndrome
E4 allele of apoprotein E
14:18
Orphan annie nuclei
13. Autosomal dominant - fatal - progressive degeneration of striatum and frontal cortex with neuronal depletion and gliosis
15:17
Berger dx
Huntington dx
PIG A
14. Triad of ovarian fibroma - ascites - hydrothorax
Kayser Fleischer ring
Meigs syndrome
Whipple dx
Prader willi syndrome
15. Small round eosinophilic masses found in dieing hepatocytes often containing chromatin remnants seen in viral hepatitis
Potter sequence
Lambert Eaton syndrome
Councilman body
Rotor syndrome
16. Paraneoplastic synd looks like myasthenia gravis - often small cell lung CA
Cori dx
Lambert Eaton syndrome
Alport syndrome
Denys Drash syndrome
17. Thiamine deficiency - cerebral dysfunction - aka alcoholic encephalopathy - hemorrhagic lesions in the mamillary bodies - confusion - ataxia - ophthalmoplegia - and memory loss plus confabulation p 105 and p115
Wernicke Korsakoff syndrome
Von economo encephalitis
Waldenstrom Macroglobulinemia
Chromosome 10
18. Single erythematous plaque on shaft of penis or scrotum
Bowen dx
ret PTC
Berger dx
GNAS1
19. Intracytoplasmic proximal dentritic eosinophilic inclusions consisting of actin seen in Alzheimers
Signet ring cell
Tay Sachs dx
Hirano bodies
Brushfield spots
20. Tumor suppressor mutated in wilms tumor
Wegener granulomatosis
WT1 and WT2
Bowen dx
Paget dx of breast
21. Deficient a1 -4 glucosidase - accumulation of glycogen in liver - heart - skeletal muscle - cardiomegaly - muscle hypotonia - spelnomegaly - intractable hypoglycemia - death from cardiorespiratory failure before age 3
Pompe dx
Von Gierke dx
Henoch Schonlein Purpura
Pancoast tumor
22. Downward displacement of cerebellar tonsils and medulla through foramen magnum
8:14
Arnold Chiari formation
Brushfield spots
Alport syndrome
23. Clear cell renal tumor seen in kids
Huntington dx
Bense Jones protein
Fabry dx
Wilms tumor
24. X linked - absence of plasma cells and serum immunoglobulins - cell mediated immunity still ok - no germinal centers - recurrent bacterial infections - resistances to fungal and viral still - btk gene defect
Nelson syndrome
Felty syndrome
Brutons Agammaglobulinemia
Arthus reaction
25. Aka osteitis deformans - increased osteoclastic and osteoblastic activity
Hfe gene
Paget dx of bone
Bowenoid papulosis
Wermer syndrome
26. Pituitary insufficiency post - partum - low TSH ACTH
Sheehan syndrome
Brutons Agammaglobulinemia
Reinke crystal
Fanconi syndrome
27. Occurs in SLE - small vegitations on either or both surfaces of valves
Hirschsprung dx
Reidel thyroiditis
Churg Strauss syndrome
Libman Sacks endocarditis
28. Nuclei arranged in horseshoe - shaped pattern about periphery of cell - characteristic of but not specific for granulomatous TB (as opposed to a foreign body giant cell that has scattered nuclei)
Raynaud phenomenon
Reidel thyroiditis
Langhans giant cell
Patau syndrome
29. Oncogenes that code for p21 proteins which are membrane signalers
Rb gene
Ras oncogenes
Gerstmann Straussler
Prader willi syndrome
30. Osteophytes at DIP joints
Wiskott Aldrich syndrome
HLA B27 antigen
Heberden nodes
Alport syndrome
31. Aka antiglomerular basement membrane dx - antibodies against alveolar and glomerular basement membranes - linear immunoflorescence
Li Fraumeni syndrome
DiGeorge syndrome
ret PTC
Goodpasture syndrome
32. Hemangioblastoma or cavernous hemangioma of cerebellum - brainstem or retina - adenomas - cysts in liver - kidney - pancreas - and other organs - increased renal cell CA - gene = short arm of chromosome 3
Von Hippel Lindau dx
Brutons Agammaglobulinemia
HLA B27 antigen
Heberden nodes
33. Tennis racket shaped cytoplasmic inclusion seen in langerhans cells (so also seen in langerhan cell histiocytosis)
Hfe gene
Foamy histiocyte
Birbeck granule
Churg Strauss syndrome
34. Aka pituitary cachexia - generalized panhypopituitarism
Dubin Johnson syndrome
BRCA1
Lesch Nyhan syndrome
Simmonds dx
35. Mucopolysaccharidosis - deficient a L iduronidase - accumulations of heparin sulfate and dermatan sulfate in heart - brain - liver - and other organs - progressive - hepatosplenomagaly - dwarfism - gargoyle - like facies - stubby fingers - corneal cl
Osler Weber Rendu syndrome
Hurler syndrome
Peyronie dx
Donovan bodies
36. Associated with 90% cases of ankylosing spondylitis - common in rheumatoid arthritis
HLA B27 antigen
BRCA2
Kawasaki dx
Burkitt lymphoma
37. DsDNA antibodies and Sm Smith antigen = highly specific for SLE
Ewing sarcoma
Stein Leventhal syndrome
ANAs in SLE
11:22
38. Gene product inhibits apoptosis
Rouleaux formation
Koilocyte
Dubin Johnson syndrome
Bcl2
39. Intracytoplasmic inclusions seen in leydig cell tumors p283
Krukenberg tumor
Hurler syndrome
Huntington dx
Reinke crystal
40. Mesangial matrix material acculmulations seen in nodular glomerulosclerosis seen in diabetic nephropathy
PIG A
E4 allele of apoprotein E
Foamy histiocyte
Kimmelstiel Wilson nodules
41. Hemihypertrophy - macroglossia - organomegaly - neonatal hypoglycemia - various embryonal tumors - deleted WT 2 gene
Osler Weber Rendu syndrome
Li Fraumeni syndrome
Letterer Siwe dx
Beckwith Weidemann syndrome
42. Variant of rheumatoid arthritis - splenmegally - neutropenia - RA
Paget dx of bone
Goodpasture syndrome
Felty syndrome
Sipple syndrome
43. Tumor suppressor mutated in Von Recklinhousen
Cri du chat syndrome
Bax
NF1
Henoch Schonlein Purpura
44. Manifestation of lymphplasmocytic lymphoma - B cell neoplasm
Waldenstrom Macroglobulinemia
Wilson dx
Raynaud disease
Letterer Siwe dx
45. Burkitts c::myc is on 8 - IG heavy chain is on 14
Orphan annie nuclei
Hunter syndrome
8:14
Brushfield spots
46. Infectious disorder - caused postencephalitic parkinsonism
Von Gierke dx
Raynaud phenomenon
Von economo encephalitis
Osler Weber Rendu syndrome
47. Aka congenital megacolon - dilation of colon due to absence of ganglion cells
Simmonds dx
Hirschsprung dx
McArdle syndrome
Virchow node
48. Osteophytes at PIP joints
Koilocyte
Lambert Eaton syndrome
Dubin Johnson syndrome
Bouchard nodes
49. Seen in Down synd - small white spots on periphery of iris
Wegener granulomatosis
Denys Drash syndrome
Brushfield spots
Waterhouse Friderichsen syndrome
50. Modest elevated serum unconj bilirubin - due to decreased uptake by liver cells and reduced activity of glucuronyl transferase
Wiskott Aldrich syndrome
Langhans giant cell
Lesch Nyhan syndrome
Gilbert syndrome
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