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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
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  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Vaginal epithelial cell with stippled appearance due to adherent coccobacilli






2. 2/neu :: oncogene (aka c - erbB2) - in breast cancer = poor prognosis






3. Gene product inhibits apoptosis






4. Triad of ovarian fibroma - ascites - hydrothorax






5. Aka hereditary hemorrhagic telangectasia - telangectasias in skin and mucous membranes - epistaxis - GI bleeds






6. Similar to Dubin Johnson with no black liver






7. Deficient hypoxanthine::guanine phosphoribosyltransferase (HGPRT) - low purine metabolism - high uric acid - thus gout - mental retardation - choreoathetosis - spasticity - self mutilation - aggressiveness






8. Defective in x- linked brutons agammaglobulinemia - B- cell tyrosine kinase






9. Aka congenital megacolon - dilation of colon due to absence of ganglion cells






10. Occurs in SLE - small vegitations on either or both surfaces of valves






11. Deficient sphingomyelinase - accumulation of sphingomyelin in phagocytes - foamy histiocytes in liver - spleen - lymph nodes - skin - hepatosplenomegaly - anemia fever - occasional neuro degeneration - half have cherry red spot macula






12. Follicular lymphoma IG heavy chain on 14 - bcl -2 oncogene on 18






13. Lots of tumors - breast CA - soft tissue sarc - brain tumors - leukemias - has loss of p53 tumor suppressor gene






14. 45 XO - female hypogonadism - hypothyroid - short - webbed neck - 1* amenorrhea p52






15. Aka acute disseminated langerhans cell histiocytosis - aggressive - usually fatal - kids hepatosplenomegaly - LAD - pancytopenia - pulmonary involvement - recurrent infections






16. Autoimmune thyroiditis - hyperthyroid - exophthalmos - increased in HLA DR3 and HLA B8 pos people






17. Acute inflammatory demyelinating dx primarily involving peripheral nerves






18. Polyostotic fibrous dysplasia - precocious puberty - caf






19. Aspirin toxicity seen in kids after acute febrile viral dx - microvesicular fatty change in liver and encephalopathy






20. Small follicles filled with eosinophilic secretion - diagnostic feature of granulose cell tumor






21. Asbestosis - yellow - brown - rod shaped body with clubbed ends - stain with Prussian blue






22. Superclavicular lymph node identifying metastatic stomach CA






23. Combination of hyperthyroidism - nodular goiter - absence of exophthalmos






24. Pigmented iris hamartoma seen in neurofibromatosis






25. Infectious disorder - caused postencephalitic parkinsonism






26. Autosomal dominant - numerous adenomatous polyps along with osteomas and soft tissue tumors






27. Nuclei arranged in horseshoe - shaped pattern about periphery of cell - characteristic of but not specific for granulomatous TB (as opposed to a foreign body giant cell that has scattered nuclei)






28. Autosomal dominant - fatal - progressive degeneration of striatum and frontal cortex with neuronal depletion and gliosis






29. Aka osteopetrosis - marble bone dx - dense skeleton - failure of osteoclastic activity






30. Binucleated or multinucleated giant cell seen in Hodgkin dx






31. Adenomatous polyps with tumors of CNS






32. Oncogenes that code for p21 proteins which are membrane signalers






33. Impaired tubular reabsorption of tryptophan - pellagra::like manifestations






34. Protooncogene mutated in medulary thyroid CA (MENII)






35. Malignant lymphoma with features resembling inflammatory disorder - young men - Reed Sternburg cells






36. Seen in urine of patients with multiple myeloma - Ig light chain either k or l






37. Peripheral neuropathy - atrophy of muscles - wet - high output cardiac failure - DCM - AV shunting - hypervolemia






38. Deficient a1 -4 glucosidase - accumulation of glycogen in liver - heart - skeletal muscle - cardiomegaly - muscle hypotonia - spelnomegaly - intractable hypoglycemia - death from cardiorespiratory failure before age 3






39. Aka pituitary cachexia - generalized panhypopituitarism






40. Deficient glucose -6- phosphatase - accumulation of glycogen in liver and kidney - hepatomegaly - hypoglycemia






41. X linked - absence of plasma cells and serum immunoglobulins - cell mediated immunity still ok - no germinal centers - recurrent bacterial infections - resistances to fungal and viral still - btk gene defect






42. Parkinsonism with autonomic dysfunction and orthostatic hypotension






43. Aka pulseless dx - inflammation and stenosis of medium and large sized arteries - often aortic arch thus aortic arch syndrome






44. Aneurysm at small artery bifurcations






45. Deficient hexosaminidase A - GM2 ganglioside accumulation - especially in neurons - CNS degeneration - mental/motor deterioration - blindness - cherry red spot on macula - death by 4 years of age






46. Associated with 90% cases of ankylosing spondylitis - common in rheumatoid arthritis






47. Metastatic stomach CA to ovary






48. Transloc seen in ewing sarcoma






49. Similar to paget breast - sometimes related to underlying adenoCA of sweat glands






50. X linked - aka immunodeficiency with thrombocytopenia and eczema - total immunoglobulins often normal - recurrent infections







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