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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Deficient muscle phosphorylase - glycogen in skeletal muscle - cramps with exertion






2. Aka allergic granulomatous angiitis - necrotizing vasculitis - variant of polyarteritis nodosa - involves pulmonary vasculature - peripheral eosinophilia - and asthma






3. Gene product inhibits apoptosis






4. Tumor suppressor mutated in wilms tumor






5. Downward displacement of cerebellar tonsils and medulla through foramen magnum






6. Hemangioblastoma or cavernous hemangioma of cerebellum - brainstem or retina - adenomas - cysts in liver - kidney - pancreas - and other organs - increased renal cell CA - gene = short arm of chromosome 3






7. Polyostotic fibrous dysplasia - precocious puberty - caf






8. Aka antiglomerular basement membrane dx - antibodies against alveolar and glomerular basement membranes - linear immunoflorescence






9. Dysplastic cell seen in HPV






10. Unknown etiology - necrotizing granulomatous vasculitis of small to medium sized vessels of the respiratory tract - kidneys - and other organs - circulating C- ANCAs






11. Port wine stain on face - ipsilateral glaucoma - vascular lesions of ocular choroidal tissue - extensive hemangiomatous involvement of meninges






12. Deficient hypoxanthine::guanine phosphoribosyltransferase (HGPRT) - low purine metabolism - high uric acid - thus gout - mental retardation - choreoathetosis - spasticity - self mutilation - aggressiveness






13. Impaired tubular reabsorption of tryptophan - pellagra::like manifestations






14. Autosomal recessive - neutropenia - albinism - cranial and peripheral neuropathy - tendency to develop repeated infections - abnormal WBCs (abnormal mictotubul formation and large cytoplasmic granules = lysosomes)






15. Aka thromboangiitis obliterans - acute inflame of small and med arteries of extremities - extending to adjacent veins and nerves - young jewish men - painful ischemic dx - worse with smoking






16. Mutation here causes pseudohypoparathyroidism






17. B Thalassemia major






18. Seen in insulinoma - episodic hyperinsulinemia and hypoglycemia - CNS dysfunction - reversal of CNS probs with administration of glucose






19. Small round blue cell tumor of bone - long bones - kids - 11:22 transloc






20. Triad of ovarian fibroma - ascites - hydrothorax






21. Autosomal dominant - numerous adenomatous polyps along with osteomas and soft tissue tumors






22. Similar to Hurler - deficient L iduronosulfate sulfatase - accumulations of heparin sulfate and dermatan sulfate - hepatospenomegaly - micrognathia - retinal degeneration - joint stiffness - mental retardation - cardiac lesions






23. Single erythematous plaque on shaft of penis or scrotum






24. Hamartomatous polyps in colon and small intest - freckles on lips - hands - genitalia - higher incidence of adeno CA of colon and other malignancies - stomach - breast - ovaries






25. Located on xsome 6 - mutation here = hereditary hemochromatosis






26. Deficient sphingomyelinase - accumulation of sphingomyelin in phagocytes - foamy histiocytes in liver - spleen - lymph nodes - skin - hepatosplenomegaly - anemia fever - occasional neuro degeneration - half have cherry red spot macula






27. Osteophytes at PIP joints






28. Area of focal interstitial myocardial inflammation characterized by fragmented collagen and fibrinoid material - by large cells (Anitschkow myocytes) and occasional multinucleated giant cells (Aschoff cells)






29. Mesangial matrix material acculmulations seen in nodular glomerulosclerosis seen in diabetic nephropathy






30. DsDNA antibodies and Sm Smith antigen = highly specific for SLE






31. Aka chronic progressive histiocytosis - not as bad as Letterer Siwe






32. Chromosome 19 - allele common in alzheimers






33. Seen in granuloma inguinale - multiple organisms filling large histiocytes






34. Malabsorption syndrome - Tropheryma wippelii bacilli - small intestine commonly affected - arthralgias - cardiac - and neuro symptoms






35. Gene product facilitates apoptosis






36. Thrombotic occlusion of major hepatic veins - abnormal pain - jaundice - hepatomegaly - acites - liver failure - assoc with polycythemia vera - hepatocellular CA - and other common neoplasms - may occur as a complication of pregnancy






37. Autosomal recessive - unusually large platelets - lack of 'GPIb IX V'






38. X linked - aka immunodeficiency with thrombocytopenia and eczema - total immunoglobulins often normal - recurrent infections






39. Autosomal dominant - fatal - progressive degeneration of striatum and frontal cortex with neuronal depletion and gliosis






40. Vasosmasm of small vessels - most often in fingers - seen with autoimmune dx like SLE - scleroderma and others (R in CREST) - recurrent vasospasm - always secondary to underlying disorder






41. Adenomatous polyps with tumors of CNS






42. Severe unconj hyperbilirubinemia due to deficient glucuronyl transferase






43. Subcutaneous fibrosis of dorsum of penis






44. = MEN1






45. Materal transmission del(15)(q11q13) - aka happy puppet syndrome - mental retardation - ataxia - seizures - inappropriate laughter






46. Burkitts c::myc is on 8 - IG heavy chain is on 14






47. Eosinophilic intracytoplasmic inclusions in hippocampus and purkinje cells seen in rabies infection






48. Thyroid replacement by fibrous tissue - unkown origin - mimics






49. Vaginal epithelial cell with stippled appearance due to adherent coccobacilli






50. X linked - absence of plasma cells and serum immunoglobulins - cell mediated immunity still ok - no germinal centers - recurrent bacterial infections - resistances to fungal and viral still - btk gene defect







Sorry!:) No result found.

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