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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Aka osteopetrosis - marble bone dx - dense skeleton - failure of osteoclastic activity






2. Autosomal recessive - hepatitis - accumulation of copper due to transport problem - low ceruloplasmin seen - kayser fleischer rings in eyes






3. Acute inflammatory demyelinating dx primarily involving peripheral nerves






4. Subcutaneous fibrosis of dorsum of penis






5. 2/neu :: oncogene (aka c - erbB2) - in breast cancer = poor prognosis






6. Aka IgA nephropathy - deposition of IgA in mesangium - benign recurrent hematuria in kids following infection






7. Variant of rheumatoid arthritis - aka juvenile rheumatoid arthritis






8. Deficient a1 -4 glucosidase - accumulation of glycogen in liver - heart - skeletal muscle - cardiomegaly - muscle hypotonia - spelnomegaly - intractable hypoglycemia - death from cardiorespiratory failure before age 3






9. Similar to paget breast - sometimes related to underlying adenoCA of sweat glands






10. Eosinophilic intracytoplasmic inclusions in hippocampus and purkinje cells seen in rabies infection






11. Binucleated or multinucleated giant cell seen in Hodgkin dx






12. Similar to Hurler - deficient L iduronosulfate sulfatase - accumulations of heparin sulfate and dermatan sulfate - hepatospenomegaly - micrognathia - retinal degeneration - joint stiffness - mental retardation - cardiac lesions






13. Seen in Down synd - small white spots on periphery of iris






14. Intracytoplasmic proximal dentritic eosinophilic inclusions consisting of actin seen in Alzheimers






15. Occurs in SLE - small vegitations on either or both surfaces of valves






16. Aka trisomy 13 - mental retardation - microcephaly - micropthalmia - brain abnormalities - cleft lip/palate - polydactyly - rockerbottom feet - congenital heart dx






17. Paracentric inversion or translocation with 17 associated with papillary thyroid CA






18. Myc :: neuroblastoma amplicatiion correlates inversely with degree of differentiation






19. Thyroid replacement by fibrous tissue - unkown origin - mimics






20. Hemangioblastoma or cavernous hemangioma of cerebellum - brainstem or retina - adenomas - cysts in liver - kidney - pancreas - and other organs - increased renal cell CA - gene = short arm of chromosome 3






21. Defective in x- linked brutons agammaglobulinemia - B- cell tyrosine kinase






22. Tennis racket shaped cytoplasmic inclusion seen in langerhans cells (so also seen in langerhan cell histiocytosis)






23. Deficient debranching enzyme amylo -1 -6- glucosidase - glycogen in liver - heart - skeletal muscle - stunted growth - hepatomegaly - hypoglycemia






24. Vaginal epithelial cell with stippled appearance due to adherent coccobacilli






25. Aka mucocutaneous lymph node syndrome - acute self - limited - infants and young kids - acute necrotizing vasculitis of small and medium vessels - fever hemorrhagic edema of conjunctivae - lips and oral mucosa - and cervical LAD - can cause coronary






26. Gene product inhibits apoptosis






27. Epithelial cells with eosinophilc granular cytoplasm seen in hashimoto






28. Aka trisomy 18 - mental retardation - prominent occiput - micrognathia (small jaw) - low::set ears - rocker::bottom feet - finger deformities - congenital heart dx






29. Area of focal interstitial myocardial inflammation characterized by fragmented collagen and fibrinoid material - by large cells (Anitschkow myocytes) and occasional multinucleated giant cells (Aschoff cells)






30. Aka osteitis deformans - increased osteoclastic and osteoblastic activity






31. Scheinker syndrome :: prion dx - fatal familial insomnia






32. Aka chronic progressive histiocytosis - not as bad as Letterer Siwe






33. X linked - aka immunodeficiency with thrombocytopenia and eczema - total immunoglobulins often normal - recurrent infections






34. Aka antiglomerular basement membrane dx - antibodies against alveolar and glomerular basement membranes - linear immunoflorescence






35. Severe unconj hyperbilirubinemia due to deficient glucuronyl transferase






36. Aka infantile progressive spinal muscular atrophy - autosomal recessive - LMN disease - infants






37. Catastrophic adrenal insuff and vascular collapse - hemorrhagic necrosis of adrenal cortex






38. Seen in hyperacute rejection - = acute inflammation - fibrinoid necrosis of small vessels - and extensive thrombosis






39. Aka hereditary hemorrhagic telangectasia - telangectasias in skin and mucous membranes - epistaxis - GI bleeds






40. Thiamine deficiency - cerebral dysfunction - aka alcoholic encephalopathy - hemorrhagic lesions in the mamillary bodies - confusion - ataxia - ophthalmoplegia - and memory loss plus confabulation p 105 and p115






41. Aka pulseless dx - inflammation and stenosis of medium and large sized arteries - often aortic arch thus aortic arch syndrome






42. Eczematoid lesion of nipple areola - large cells with clear 'halo like' area - invade epidermis - underlying ductal CA






43. Small round blue cell tumor of bone - long bones - kids - 11:22 transloc






44. Mucinous cell - characteristic of stomach CA met to ovary (krukenberg tumor)






45. Ovarian tumor resembling bladder transitional epith






46. = MEN1






47. X linked - absence of plasma cells and serum immunoglobulins - cell mediated immunity still ok - no germinal centers - recurrent bacterial infections - resistances to fungal and viral still - btk gene defect






48. This comes in a wet variety and a dry one - they are both Vit B1 thiamine deficiency






49. 45 XO - female hypogonadism - hypothyroid - short - webbed neck - 1* amenorrhea p52






50. Autosomal dominant - numerous adenomatous polyps along with osteomas and soft tissue tumors







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