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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Mucinous cell - characteristic of stomach CA met to ovary (krukenberg tumor)






2. Aka thromboangiitis obliterans - acute inflame of small and med arteries of extremities - extending to adjacent veins and nerves - young jewish men - painful ischemic dx - worse with smoking






3. Polyostotic fibrous dysplasia - precocious puberty - caf






4. Aka velocardiofacial syndrome and CATCH 22 syndrome - micro deletion of 22q11 - Cardiac abnormalities - Abnormal facies - T cell deficit due to thymic hypoplasia - Cleft palate - Hypocalcemia due to hypoparathyroidism - from poor development of 3rd a






5. At least 2 X and one Y - hypogonadism - tall - gynecomastia - low testosterone - high pituitary gonadotropins - infertility -






6. Acute inflammatory demyelinating dx primarily involving peripheral nerves






7. Similar to Hurler - deficient L iduronosulfate sulfatase - accumulations of heparin sulfate and dermatan sulfate - hepatospenomegaly - micrognathia - retinal degeneration - joint stiffness - mental retardation - cardiac lesions






8. Autosomal recessive - unusually large platelets - lack of 'GPIb IX V'






9. Aka subcortical leukoencephalopathy - assoc with HTN - multiple lacunar infarcts and progressive demyelination in subcortical area






10. Autosomal recessive - conj hyperbilirubinemia - defect in bili transport - black color to liver






11. DsDNA antibodies and Sm Smith antigen = highly specific for SLE






12. Seen in insulinoma - episodic hyperinsulinemia and hypoglycemia - CNS dysfunction - reversal of CNS probs with administration of glucose






13. Aka trisomy 18 - mental retardation - prominent occiput - micrognathia (small jaw) - low::set ears - rocker::bottom feet - finger deformities - congenital heart dx






14. Autoimmune hypothyroid - hurthle cells common






15. Parkinsonism with autonomic dysfunction and orthostatic hypotension






16. Hemangioblastoma or cavernous hemangioma of cerebellum - brainstem or retina - adenomas - cysts in liver - kidney - pancreas - and other organs - increased renal cell CA - gene = short arm of chromosome 3






17. Tumor suppressor mutated in wilms tumor






18. Deficient fibrillin (constituent of microfibrils) - arachnodactyly - ectopia lentis - aortic aneurysm - mitral valve prolapsed






19. Protooncogene mutated in medulary thyroid CA (MENII)






20. Aka antiglomerular basement membrane dx - antibodies against alveolar and glomerular basement membranes - linear immunoflorescence






21. Deficient glucocerebrosidase - accumulation of glucocerebroside in cells of mononuclear phagocyte system 3 types ::






22. Aka osteitis deformans - increased osteoclastic and osteoblastic activity






23. = MEN2a






24. Follicular lymphoma IG heavy chain on 14 - bcl -2 oncogene on 18






25. Deficient sphingomyelinase - accumulation of sphingomyelin in phagocytes - foamy histiocytes in liver - spleen - lymph nodes - skin - hepatosplenomegaly - anemia fever - occasional neuro degeneration - half have cherry red spot macula






26. Aka lentigo maligna - precursor to lentigo maligna melanoma






27. Malabsorption syndrome - Tropheryma wippelii bacilli - small intestine commonly affected - arthralgias - cardiac - and neuro symptoms






28. Primary aldosteronism






29. Philadelphia chromosome - CML bcr abl fusion c - abl on 9 - bcr on 22






30. Seen in urine of patients with multiple myeloma - Ig light chain either k or l






31. Manifestation of lymphplasmocytic lymphoma - B cell neoplasm






32. Gene product facilitates apoptosis






33. Scheinker syndrome :: prion dx - fatal familial insomnia






34. Intracytoplasmic inclusions seen in leydig cell tumors p283






35. Infectious disorder - caused postencephalitic parkinsonism






36. Non::neoplastic tumor like masses - fibrous replacement of resorbed bone






37. Osteophytes at DIP joints






38. Mesangial matrix material acculmulations seen in nodular glomerulosclerosis seen in diabetic nephropathy






39. Aka acute disseminated langerhans cell histiocytosis - aggressive - usually fatal - kids hepatosplenomegaly - LAD - pancytopenia - pulmonary involvement - recurrent infections






40. Area of focal interstitial myocardial inflammation characterized by fragmented collagen and fibrinoid material - by large cells (Anitschkow myocytes) and occasional multinucleated giant cells (Aschoff cells)






41. Single erythematous plaque on shaft of penis or scrotum






42. Oligohydramnios causes fetus to be smashed






43. Diffuse nodular diabetic glomerulosclerosis






44. Combination of hyperthyroidism - nodular goiter - absence of exophthalmos






45. Hereditary nonpolyposis colon cancer - DNA repair genes messed up






46. Aspirin toxicity seen in kids after acute febrile viral dx - microvesicular fatty change in liver and encephalopathy






47. Downward displacement of cerebellar tonsils and medulla through foramen magnum






48. Aka pulseless dx - inflammation and stenosis of medium and large sized arteries - often aortic arch thus aortic arch syndrome






49. Aka hereditary hemorrhagic telangectasia - telangectasias in skin and mucous membranes - epistaxis - GI bleeds






50. X linked - aka immunodeficiency with thrombocytopenia and eczema - total immunoglobulins often normal - recurrent infections







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