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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. X linked - aka immunodeficiency with thrombocytopenia and eczema - total immunoglobulins often normal - recurrent infections






2. Deficient glucose -6- phosphatase - accumulation of glycogen in liver and kidney - hepatomegaly - hypoglycemia






3. Malabsorption syndrome - Tropheryma wippelii bacilli - small intestine commonly affected - arthralgias - cardiac - and neuro symptoms






4. = MEN2a






5. Small round blue cell tumor of bone - long bones - kids - 11:22 transloc






6. Aka mucocutaneous lymph node syndrome - acute self - limited - infants and young kids - acute necrotizing vasculitis of small and medium vessels - fever hemorrhagic edema of conjunctivae - lips and oral mucosa - and cervical LAD - can cause coronary






7. Minute neutrophilic abscesses found within parakeratotic stratum corneum in psoriasis






8. Lots of tumors - breast CA - soft tissue sarc - brain tumors - leukemias - has loss of p53 tumor suppressor gene






9. Diffuse nodular diabetic glomerulosclerosis






10. Port wine stain on face - ipsilateral glaucoma - vascular lesions of ocular choroidal tissue - extensive hemangiomatous involvement of meninges






11. Single erythematous plaque on shaft of penis or scrotum






12. Acute inflammatory demyelinating dx primarily involving peripheral nerves






13. Area of focal interstitial myocardial inflammation characterized by fragmented collagen and fibrinoid material - by large cells (Anitschkow myocytes) and occasional multinucleated giant cells (Aschoff cells)






14. Transloc seen in ewing sarcoma






15. Small round eosinophilic masses found in dieing hepatocytes often containing chromatin remnants seen in viral hepatitis






16. Acute promyelocytic leukemia PML gene on 15 and RARa on 17






17. Eczematoid lesion of nipple areola - large cells with clear 'halo like' area - invade epidermis - underlying ductal CA






18. Chromosome 19 - allele common in alzheimers






19. 2/neu :: oncogene (aka c - erbB2) - in breast cancer = poor prognosis






20. Mutation here causes pseudohypoparathyroidism






21. Ovarian tumor resembling bladder transitional epith






22. Sphingomyelin containing phagocytes seen in Niemman::Pick dx in liver - spleen - lymph nodes and skin






23. Infectious disorder - caused postencephalitic parkinsonism






24. Unknown etiology - necrotizing granulomatous vasculitis of small to medium sized vessels of the respiratory tract - kidneys - and other organs - circulating C- ANCAs






25. Autosomal dominant - numerous adenomatous polyps along with osteomas and soft tissue tumors






26. Deficient a1 -4 glucosidase - accumulation of glycogen in liver - heart - skeletal muscle - cardiomegaly - muscle hypotonia - spelnomegaly - intractable hypoglycemia - death from cardiorespiratory failure before age 3






27. Mutation = paroxysmal nocturnal hemoglobinuria






28. Similar to paget breast - sometimes related to underlying adenoCA of sweat glands






29. Defective in x- linked brutons agammaglobulinemia - B- cell tyrosine kinase






30. Aka congenital megacolon - dilation of colon due to absence of ganglion cells






31. Autosomal recessive - unusually large platelets - lack of 'GPIb IX V'






32. Associated with 90% cases of ankylosing spondylitis - common in rheumatoid arthritis






33. Dysplastic cell seen in HPV






34. Clear cell renal tumor seen in kids






35. Binucleated or multinucleated giant cell seen in Hodgkin dx






36. Deficient hypoxanthine::guanine phosphoribosyltransferase (HGPRT) - low purine metabolism - high uric acid - thus gout - mental retardation - choreoathetosis - spasticity - self mutilation - aggressiveness






37. B1 thiamine - B2 riboflavin - B3 niacin - B6 pyridoxine - B12 cobalamin - C ascorbic acid - D calciferol - E a::tocopherol






38. Deficient sphingomyelinase - accumulation of sphingomyelin in phagocytes - foamy histiocytes in liver - spleen - lymph nodes - skin - hepatosplenomegaly - anemia fever - occasional neuro degeneration - half have cherry red spot macula






39. Osteophytes at DIP joints






40. Urethritis - conjunctivitis - arthritis - associated with venereal or intestinal infection






41. Iron deficient anemia associated with upper::esophageal web






42. Esophageal diverticulum just above upper esoph sphincter






43. Myc :: neuroblastoma amplicatiion correlates inversely with degree of differentiation






44. Gene product facilitates apoptosis - decreases bcl::2 and increases Bax






45. Seen in urine of patients with multiple myeloma - Ig light chain either k or l






46. Thyroid replacement by fibrous tissue - unkown origin - mimics






47. DsDNA antibodies and Sm Smith antigen = highly specific for SLE






48. Paraneoplastic synd looks like myasthenia gravis - often small cell lung CA






49. Intracytoplasmic proximal dentritic eosinophilic inclusions consisting of actin seen in Alzheimers






50. Superclavicular lymph node identifying metastatic stomach CA