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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Dysplastic cell seen in HPV






2. B Thalassemia major






3. Aka infantile progressive spinal muscular atrophy - autosomal recessive - LMN disease - infants






4. At least 2 X and one Y - hypogonadism - tall - gynecomastia - low testosterone - high pituitary gonadotropins - infertility -






5. Gene product facilitates apoptosis - decreases bcl::2 and increases Bax






6. Gene product inhibits apoptosis






7. DsDNA antibodies and Sm Smith antigen = highly specific for SLE






8. Appears as multiple wart - like lesions resembling condyloma accuminatum






9. Associated with breast alone (isn't one of these associated with prostate? Check)






10. Superclavicular lymph node identifying metastatic stomach CA






11. Aka pulseless dx - inflammation and stenosis of medium and large sized arteries - often aortic arch thus aortic arch syndrome






12. Malabsorption syndrome - Tropheryma wippelii bacilli - small intestine commonly affected - arthralgias - cardiac - and neuro symptoms






13. Associated with papillary thyroid CA






14. Aka superior sulcus tumor - seen in bronchogenic CA - often with Horner's






15. Aka trisomy 18 - mental retardation - prominent occiput - micrognathia (small jaw) - low::set ears - rocker::bottom feet - finger deformities - congenital heart dx






16. This comes in a wet variety and a dry one - they are both Vit B1 thiamine deficiency






17. Deficient hypoxanthine::guanine phosphoribosyltransferase (HGPRT) - low purine metabolism - high uric acid - thus gout - mental retardation - choreoathetosis - spasticity - self mutilation - aggressiveness






18. Aka congenital megacolon - dilation of colon due to absence of ganglion cells






19. Triad of ovarian fibroma - ascites - hydrothorax






20. Area of focal interstitial myocardial inflammation characterized by fragmented collagen and fibrinoid material - by large cells (Anitschkow myocytes) and occasional multinucleated giant cells (Aschoff cells)






21. Seen in granuloma inguinale - multiple organisms filling large histiocytes






22. Impaired tubular reabsorption of tryptophan - pellagra::like manifestations






23. Materal transmission del(15)(q11q13) - aka happy puppet syndrome - mental retardation - ataxia - seizures - inappropriate laughter






24. Deficient debranching enzyme amylo -1 -6- glucosidase - glycogen in liver - heart - skeletal muscle - stunted growth - hepatomegaly - hypoglycemia






25. Deficient sphingomyelinase - accumulation of sphingomyelin in phagocytes - foamy histiocytes in liver - spleen - lymph nodes - skin - hepatosplenomegaly - anemia fever - occasional neuro degeneration - half have cherry red spot macula






26. Renal tubular dysfunction - impaired reabsorption of glucose - amino acids - phosphate - and bicarb thus glycosuria - hyperphosphaturia - hypophosphatemia - aminoaciduria - systemic acidosis






27. Intracytoplasmic inclusions seen in leydig cell tumors p283






28. Seen in papillary thyroid CA






29. Aka neurofibromatosis - neurofibromas in skin - schwannomas of CN VIII - caf






30. Aka velocardiofacial syndrome and CATCH 22 syndrome - micro deletion of 22q11 - Cardiac abnormalities - Abnormal facies - T cell deficit due to thymic hypoplasia - Cleft palate - Hypocalcemia due to hypoparathyroidism - from poor development of 3rd a






31. Oligohydramnios causes fetus to be smashed






32. Aka IgA nephropathy - deposition of IgA in mesangium - benign recurrent hematuria in kids following infection






33. Aka osteitis deformans - increased osteoclastic and osteoblastic activity






34. Single erythematous plaque on shaft of penis or scrotum






35. Seen in Down synd - small white spots on periphery of iris






36. Associated with 90% cases of ankylosing spondylitis - common in rheumatoid arthritis






37. Clear cell renal tumor seen in kids






38. Aka allergic granulomatous angiitis - necrotizing vasculitis - variant of polyarteritis nodosa - involves pulmonary vasculature - peripheral eosinophilia - and asthma






39. Autosomal dominant - fatal - progressive degeneration of striatum and frontal cortex with neuronal depletion and gliosis






40. Autoimmune hypothyroid - hurthle cells common






41. Thrombotic occlusion of major hepatic veins - abnormal pain - jaundice - hepatomegaly - acites - liver failure - assoc with polycythemia vera - hepatocellular CA - and other common neoplasms - may occur as a complication of pregnancy






42. Hemihypertrophy - macroglossia - organomegaly - neonatal hypoglycemia - various embryonal tumors - deleted WT 2 gene






43. Oncogenes that code for p21 proteins which are membrane signalers






44. Deficient glucocerebrosidase - accumulation of glucocerebroside in cells of mononuclear phagocyte system 3 types ::






45. Modest elevated serum unconj bilirubin - due to decreased uptake by liver cells and reduced activity of glucuronyl transferase






46. Aka antiglomerular basement membrane dx - antibodies against alveolar and glomerular basement membranes - linear immunoflorescence






47. Acute inflammatory demyelinating dx primarily involving peripheral nerves






48. Osteophytes at PIP joints






49. Paracentric inversion or translocation with 17 associated with papillary thyroid CA






50. B1 thiamine - B2 riboflavin - B3 niacin - B6 pyridoxine - B12 cobalamin - C ascorbic acid - D calciferol - E a::tocopherol