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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Aka polycystic ovary syndrome - young women - amenorrhea - infertility - obesity - hirsutism






2. Seen in insulinoma - episodic hyperinsulinemia and hypoglycemia - CNS dysfunction - reversal of CNS probs with administration of glucose






3. Mutation here causes pseudohypoparathyroidism






4. Hemangioblastoma or cavernous hemangioma of cerebellum - brainstem or retina - adenomas - cysts in liver - kidney - pancreas - and other organs - increased renal cell CA - gene = short arm of chromosome 3






5. Oligohydramnios causes fetus to be smashed






6. DsDNA antibodies and Sm Smith antigen = highly specific for SLE






7. Autosomal dominant - numerous adenomatous polyps along with osteomas and soft tissue tumors






8. Parkinsonism with autonomic dysfunction and orthostatic hypotension






9. Different in that it is the primary disorder - recurrent vasospasm of small arteries and venules - pallor - cyanosis - fingers and toes - young healthy women






10. Occurs in SLE - small vegitations on either or both surfaces of valves






11. Autosomal recessive - neutropenia - albinism - cranial and peripheral neuropathy - tendency to develop repeated infections - abnormal WBCs (abnormal mictotubul formation and large cytoplasmic granules = lysosomes)






12. Superclavicular lymph node identifying metastatic stomach CA






13. Eczematoid lesion of nipple areola - large cells with clear 'halo like' area - invade epidermis - underlying ductal CA






14. Catastrophic adrenal insuff and vascular collapse - hemorrhagic necrosis of adrenal cortex






15. Mucinous cell - characteristic of stomach CA met to ovary (krukenberg tumor)






16. Asbestosis - yellow - brown - rod shaped body with clubbed ends - stain with Prussian blue






17. Aka thromboangiitis obliterans - acute inflame of small and med arteries of extremities - extending to adjacent veins and nerves - young jewish men - painful ischemic dx - worse with smoking






18. Paternal transmission del (15)(q11q13) - hypogonad - hypotonia - mental retardation - behavior probs - uncrontrolled appetite






19. Acute promyelocytic leukemia PML gene on 15 and RARa on 17






20. Aspirin toxicity seen in kids after acute febrile viral dx - microvesicular fatty change in liver and encephalopathy






21. Metastatic stomach CA to ovary






22. Aka mucocutaneous lymph node syndrome - acute self - limited - infants and young kids - acute necrotizing vasculitis of small and medium vessels - fever hemorrhagic edema of conjunctivae - lips and oral mucosa - and cervical LAD - can cause coronary






23. Ring of copper deposited around iris seen in Wilson






24. Hemihypertrophy - macroglossia - organomegaly - neonatal hypoglycemia - various embryonal tumors - deleted WT 2 gene






25. Intracytoplasmic proximal dentritic eosinophilic inclusions consisting of actin seen in Alzheimers






26. Osteophytes at PIP joints






27. Autosomal dominant - fatal - progressive degeneration of striatum and frontal cortex with neuronal depletion and gliosis






28. Aka pulseless dx - inflammation and stenosis of medium and large sized arteries - often aortic arch thus aortic arch syndrome






29. Aka osteitis deformans - increased osteoclastic and osteoblastic activity






30. Oncogenes that code for p21 proteins which are membrane signalers






31. Gene product facilitates apoptosis






32. Intra::alveolar hemosiderin - laden macrophages caused by RBCs from capillary rupture 2* to pulmonary HTN






33. Associated with Wegener granulomatosis






34. Seen in CLL - leukemic B- cells that are fragile






35. Philadelphia chromosome - CML bcr abl fusion c - abl on 9 - bcr on 22






36. Chromosome 19 - allele common in alzheimers






37. Manifestation of lymphplasmocytic lymphoma - B cell neoplasm






38. B1 thiamine - B2 riboflavin - B3 niacin - B6 pyridoxine - B12 cobalamin - C ascorbic acid - D calciferol - E a::tocopherol






39. Autosomal recessive - conj hyperbilirubinemia - defect in bili transport - black color to liver






40. Seen in urine of patients with multiple myeloma - Ig light chain either k or l






41. Aggressive B- cell lymphoma - EBV - starry sky appearance - c myc






42. Gene mutated in achondroplasia (most common form of dwarfism) - located at 4p16.3






43. Defective cilia - sinusitis - bronchiectasis - situs inversus - sometimes hearing loss and male sterility






44. Thrombotic occlusion of major hepatic veins - abnormal pain - jaundice - hepatomegaly - acites - liver failure - assoc with polycythemia vera - hepatocellular CA - and other common neoplasms - may occur as a complication of pregnancy






45. Aka velocardiofacial syndrome and CATCH 22 syndrome - micro deletion of 22q11 - Cardiac abnormalities - Abnormal facies - T cell deficit due to thymic hypoplasia - Cleft palate - Hypocalcemia due to hypoparathyroidism - from poor development of 3rd a






46. 45 XO - female hypogonadism - hypothyroid - short - webbed neck - 1* amenorrhea p52






47. X linked - absence of plasma cells and serum immunoglobulins - cell mediated immunity still ok - no germinal centers - recurrent bacterial infections - resistances to fungal and viral still - btk gene defect






48. Sphingomyelin containing phagocytes seen in Niemman::Pick dx in liver - spleen - lymph nodes and skin






49. Abnormal WT 1 gene - intersexual disorders - nephropathy - wilms tumor






50. Minute neutrophilic abscesses found within parakeratotic stratum corneum in psoriasis