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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Vasosmasm of small vessels - most often in fingers - seen with autoimmune dx like SLE - scleroderma and others (R in CREST) - recurrent vasospasm - always secondary to underlying disorder






2. Aka subcortical leukoencephalopathy - assoc with HTN - multiple lacunar infarcts and progressive demyelination in subcortical area






3. Seen in Down synd - small white spots on periphery of iris






4. Aka hereditary hemorrhagic telangectasia - telangectasias in skin and mucous membranes - epistaxis - GI bleeds






5. Nystagmus - intention tremor - scanning speech - seen in MS






6. Aka polycystic ovary syndrome - young women - amenorrhea - infertility - obesity - hirsutism






7. Eczematoid lesion of nipple areola - large cells with clear 'halo like' area - invade epidermis - underlying ductal CA






8. 2/neu :: oncogene (aka c - erbB2) - in breast cancer = poor prognosis






9. Aka neurofibromatosis - neurofibromas in skin - schwannomas of CN VIII - caf






10. Protooncogene mutated in medulary thyroid CA (MENII)






11. Triad of ovarian fibroma - ascites - hydrothorax






12. B1 thiamine - B2 riboflavin - B3 niacin - B6 pyridoxine - B12 cobalamin - C ascorbic acid - D calciferol - E a::tocopherol






13. Autosomal recessive - unusually large platelets - lack of 'GPIb IX V'






14. Adenomatous polyps with tumors of CNS






15. Radiologic appearance of periostium in bone tumors






16. This comes in a wet variety and a dry one - they are both Vit B1 thiamine deficiency






17. Hemorrhagic urticaria of extensor surgaces of arms - legs - and buttocks - with fever - arthralgias - and GI renal involvement similar to IgA nephropathy - associated with URIs






18. Variant of rheumatoid arthritis - splenmegally - neutropenia - RA






19. Tumor suppressor mutated in Von Recklinhousen






20. Thrombotic occlusion of major hepatic veins - abnormal pain - jaundice - hepatomegaly - acites - liver failure - assoc with polycythemia vera - hepatocellular CA - and other common neoplasms - may occur as a complication of pregnancy






21. Lots of tumors - breast CA - soft tissue sarc - brain tumors - leukemias - has loss of p53 tumor suppressor gene






22. Osteophytes at DIP joints






23. Malabsorption syndrome - Tropheryma wippelii bacilli - small intestine commonly affected - arthralgias - cardiac - and neuro symptoms






24. Abnormal WT 1 gene - intersexual disorders - nephropathy - wilms tumor






25. Deficient debranching enzyme amylo -1 -6- glucosidase - glycogen in liver - heart - skeletal muscle - stunted growth - hepatomegaly - hypoglycemia






26. Similar to paget breast - sometimes related to underlying adenoCA of sweat glands






27. Transloc seen in ewing sarcoma






28. Defective in x- linked brutons agammaglobulinemia - B- cell tyrosine kinase






29. Aka chronic progressive histiocytosis - not as bad as Letterer Siwe






30. Small round eosinophilic masses found in dieing hepatocytes often containing chromatin remnants seen in viral hepatitis






31. Dysplastic cell seen in HPV






32. Aka angiokeratoma corporis diffusum universal - deficient a::galactosidase A - accumulate ceramide trihexoside - skin lesions angiokeratomas - fever - burning pain in extremities - cardiovascular and cerebrovascular involvement - death as adult by re






33. Subcutaneous fibrosis of dorsum of penis






34. Gene product inhibits apoptosis






35. Hereditary nephritis associated with nerve deafness and ocular disorders - mutation in gene for the a5 chain of type IV collagen






36. Aneurysm at small artery bifurcations






37. Mutation here causes pseudohypoparathyroidism






38. Aka acute disseminated langerhans cell histiocytosis - aggressive - usually fatal - kids hepatosplenomegaly - LAD - pancytopenia - pulmonary involvement - recurrent infections






39. Tumor suppressor mutated in breast and ovary






40. Urethritis - conjunctivitis - arthritis - associated with venereal or intestinal infection






41. Aka mucocutaneous lymph node syndrome - acute self - limited - infants and young kids - acute necrotizing vasculitis of small and medium vessels - fever hemorrhagic edema of conjunctivae - lips and oral mucosa - and cervical LAD - can cause coronary






42. Asbestosis - yellow - brown - rod shaped body with clubbed ends - stain with Prussian blue






43. Deficient hexosaminidase A - GM2 ganglioside accumulation - especially in neurons - CNS degeneration - mental/motor deterioration - blindness - cherry red spot on macula - death by 4 years of age






44. Diffuse nodular diabetic glomerulosclerosis






45. Catastrophic adrenal insuff and vascular collapse - hemorrhagic necrosis of adrenal cortex






46. Manifestation of lymphplasmocytic lymphoma - B cell neoplasm






47. Appears as multiple wart - like lesions resembling condyloma accuminatum






48. Aka thromboangiitis obliterans - acute inflame of small and med arteries of extremities - extending to adjacent veins and nerves - young jewish men - painful ischemic dx - worse with smoking






49. Area of focal interstitial myocardial inflammation characterized by fragmented collagen and fibrinoid material - by large cells (Anitschkow myocytes) and occasional multinucleated giant cells (Aschoff cells)






50. Aka velocardiofacial syndrome and CATCH 22 syndrome - micro deletion of 22q11 - Cardiac abnormalities - Abnormal facies - T cell deficit due to thymic hypoplasia - Cleft palate - Hypocalcemia due to hypoparathyroidism - from poor development of 3rd a