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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Vaginal epithelial cell with stippled appearance due to adherent coccobacilli






2. Aka pulseless dx - inflammation and stenosis of medium and large sized arteries - often aortic arch thus aortic arch syndrome






3. Diffuse nodular diabetic glomerulosclerosis






4. Mutation here causes pseudohypoparathyroidism






5. Deficient hexosaminidase A - GM2 ganglioside accumulation - especially in neurons - CNS degeneration - mental/motor deterioration - blindness - cherry red spot on macula - death by 4 years of age






6. Paraneoplastic synd looks like myasthenia gravis - often small cell lung CA






7. Eosinophilic intracytoplasmic inclusions in hippocampus and purkinje cells seen in rabies infection






8. Materal transmission del(15)(q11q13) - aka happy puppet syndrome - mental retardation - ataxia - seizures - inappropriate laughter






9. Aka trisomy 18 - mental retardation - prominent occiput - micrognathia (small jaw) - low::set ears - rocker::bottom feet - finger deformities - congenital heart dx






10. Autosomal dominant - fatal - progressive degeneration of striatum and frontal cortex with neuronal depletion and gliosis






11. Adenomatous polyps with tumors of CNS






12. Similar to paget breast - sometimes related to underlying adenoCA of sweat glands






13. Aka mucocutaneous lymph node syndrome - acute self - limited - infants and young kids - acute necrotizing vasculitis of small and medium vessels - fever hemorrhagic edema of conjunctivae - lips and oral mucosa - and cervical LAD - can cause coronary






14. Gene product facilitates apoptosis






15. Thiamine deficiency - cerebral dysfunction - aka alcoholic encephalopathy - hemorrhagic lesions in the mamillary bodies - confusion - ataxia - ophthalmoplegia - and memory loss plus confabulation p 105 and p115






16. Aka acute disseminated langerhans cell histiocytosis - aggressive - usually fatal - kids hepatosplenomegaly - LAD - pancytopenia - pulmonary involvement - recurrent infections






17. Osteophytes at DIP joints






18. Malignant lymphoma with features resembling inflammatory disorder - young men - Reed Sternburg cells






19. Defective cilia - sinusitis - bronchiectasis - situs inversus - sometimes hearing loss and male sterility






20. Aka subcortical leukoencephalopathy - assoc with HTN - multiple lacunar infarcts and progressive demyelination in subcortical area






21. Gene product facilitates apoptosis - decreases bcl::2 and increases Bax






22. Area of focal interstitial myocardial inflammation characterized by fragmented collagen and fibrinoid material - by large cells (Anitschkow myocytes) and occasional multinucleated giant cells (Aschoff cells)






23. Renal tubular dysfunction - impaired reabsorption of glucose - amino acids - phosphate - and bicarb thus glycosuria - hyperphosphaturia - hypophosphatemia - aminoaciduria - systemic acidosis






24. Metastatic stomach CA to ovary






25. Intracytoplasmic inclusions seen in leydig cell tumors p283






26. Transloc seen in ewing sarcoma






27. Tumor suppressor mutated in wilms tumor






28. Hemorrhagic urticaria of extensor surgaces of arms - legs - and buttocks - with fever - arthralgias - and GI renal involvement similar to IgA nephropathy - associated with URIs






29. Follicular lymphoma IG heavy chain on 14 - bcl -2 oncogene on 18






30. Autoimmune hypothyroid - hurthle cells common






31. Seen in hyperacute rejection - = acute inflammation - fibrinoid necrosis of small vessels - and extensive thrombosis






32. Chromosome 19 - allele common in alzheimers






33. Seen in urine of patients with multiple myeloma - Ig light chain either k or l






34. Aka pituitary cachexia - generalized panhypopituitarism






35. Aka velocardiofacial syndrome and CATCH 22 syndrome - micro deletion of 22q11 - Cardiac abnormalities - Abnormal facies - T cell deficit due to thymic hypoplasia - Cleft palate - Hypocalcemia due to hypoparathyroidism - from poor development of 3rd a






36. = MEN1






37. Acute inflammatory demyelinating dx primarily involving peripheral nerves






38. Port wine stain on face - ipsilateral glaucoma - vascular lesions of ocular choroidal tissue - extensive hemangiomatous involvement of meninges






39. X linked - absence of plasma cells and serum immunoglobulins - cell mediated immunity still ok - no germinal centers - recurrent bacterial infections - resistances to fungal and viral still - btk gene defect






40. Impaired tubular reabsorption of tryptophan - pellagra::like manifestations






41. Thyroid replacement by fibrous tissue - unkown origin - mimics






42. Defective in x- linked brutons agammaglobulinemia - B- cell tyrosine kinase






43. This comes in a wet variety and a dry one - they are both Vit B1 thiamine deficiency






44. Gene mutated in achondroplasia (most common form of dwarfism) - located at 4p16.3






45. Seen in insulinoma - episodic hyperinsulinemia and hypoglycemia - CNS dysfunction - reversal of CNS probs with administration of glucose






46. Deficient muscle phosphorylase - glycogen in skeletal muscle - cramps with exertion






47. X linked - aka immunodeficiency with thrombocytopenia and eczema - total immunoglobulins often normal - recurrent infections






48. Esophageal diverticulum just above upper esoph sphincter






49. Tumor suppressor common in familial polyposis coli and adenoCA of colon as well as other tumors






50. Unknown etiology - necrotizing granulomatous vasculitis of small to medium sized vessels of the respiratory tract - kidneys - and other organs - circulating C- ANCAs