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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Hereditary nephritis associated with nerve deafness and ocular disorders - mutation in gene for the a5 chain of type IV collagen






2. Iron deficient anemia associated with upper::esophageal web






3. Autosomal dominant - numerous adenomatous polyps along with osteomas and soft tissue tumors






4. Area of focal interstitial myocardial inflammation characterized by fragmented collagen and fibrinoid material - by large cells (Anitschkow myocytes) and occasional multinucleated giant cells (Aschoff cells)






5. Esophageal diverticulum just above upper esoph sphincter






6. This comes in a wet variety and a dry one - they are both Vit B1 thiamine deficiency






7. Malignant lymphoma with features resembling inflammatory disorder - young men - Reed Sternburg cells






8. Aka thromboangiitis obliterans - acute inflame of small and med arteries of extremities - extending to adjacent veins and nerves - young jewish men - painful ischemic dx - worse with smoking






9. Acute inflammatory demyelinating dx primarily involving peripheral nerves






10. Subcutaneous fibrosis of dorsum of penis






11. Hemihypertrophy - macroglossia - organomegaly - neonatal hypoglycemia - various embryonal tumors - deleted WT 2 gene






12. Catastrophic adrenal insuff and vascular collapse - hemorrhagic necrosis of adrenal cortex






13. Vasosmasm of small vessels - most often in fingers - seen with autoimmune dx like SLE - scleroderma and others (R in CREST) - recurrent vasospasm - always secondary to underlying disorder






14. Appears as multiple wart - like lesions resembling condyloma accuminatum






15. Aka superior sulcus tumor - seen in bronchogenic CA - often with Horner's






16. Autosomal recessive - unusually large platelets - lack of 'GPIb IX V'






17. Aka lentigo maligna - precursor to lentigo maligna melanoma






18. Aka pulseless dx - inflammation and stenosis of medium and large sized arteries - often aortic arch thus aortic arch syndrome






19. Urethritis - conjunctivitis - arthritis - associated with venereal or intestinal infection






20. Aka allergic granulomatous angiitis - necrotizing vasculitis - variant of polyarteritis nodosa - involves pulmonary vasculature - peripheral eosinophilia - and asthma






21. Lots of tumors - breast CA - soft tissue sarc - brain tumors - leukemias - has loss of p53 tumor suppressor gene






22. Polyostotic fibrous dysplasia - precocious puberty - caf






23. Gene product facilitates apoptosis - decreases bcl::2 and increases Bax






24. Acute promyelocytic leukemia PML gene on 15 and RARa on 17






25. Aka hereditary hemorrhagic telangectasia - telangectasias in skin and mucous membranes - epistaxis - GI bleeds






26. Similar to paget breast - sometimes related to underlying adenoCA of sweat glands






27. Binucleated or multinucleated giant cell seen in Hodgkin dx






28. Deficient fibrillin (constituent of microfibrils) - arachnodactyly - ectopia lentis - aortic aneurysm - mitral valve prolapsed






29. Radiologic appearance of periostium in bone tumors






30. Oligohydramnios causes fetus to be smashed






31. Autosomal recessive - conj hyperbilirubinemia - defect in bili transport - black color to liver






32. 2/neu :: oncogene (aka c - erbB2) - in breast cancer = poor prognosis






33. Philadelphia chromosome - CML bcr abl fusion c - abl on 9 - bcr on 22






34. Vaginal epithelial cell with stippled appearance due to adherent coccobacilli






35. Ring of copper deposited around iris seen in Wilson






36. Adenomatous polyps with tumors of CNS






37. Associated with Wegener granulomatosis






38. Aka osteopetrosis - marble bone dx - dense skeleton - failure of osteoclastic activity






39. Gene product inhibits apoptosis






40. Deficient glucose -6- phosphatase - accumulation of glycogen in liver and kidney - hepatomegaly - hypoglycemia






41. Hemorrhagic urticaria of extensor surgaces of arms - legs - and buttocks - with fever - arthralgias - and GI renal involvement similar to IgA nephropathy - associated with URIs






42. Aneurysm at small artery bifurcations






43. Similar to Dubin Johnson with no black liver






44. Nystagmus - intention tremor - scanning speech - seen in MS






45. Seen in Down synd - small white spots on periphery of iris






46. Autoimmune hypothyroid - hurthle cells common






47. Aka mucocutaneous lymph node syndrome - acute self - limited - infants and young kids - acute necrotizing vasculitis of small and medium vessels - fever hemorrhagic edema of conjunctivae - lips and oral mucosa - and cervical LAD - can cause coronary






48. Thyroid replacement by fibrous tissue - unkown origin - mimics






49. Single erythematous plaque on shaft of penis or scrotum






50. Infectious disorder - caused postencephalitic parkinsonism