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Test your basic knowledge |
USMLE Brs Pathology Vocab
Start Test
Study First
Subjects
:
health-sciences
,
usmle
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Severe unconj hyperbilirubinemia due to deficient glucuronyl transferase
Plummer Vinson syndrome
Turner syndrome
Reed Sternburg cell
Crigler Najjar syndrome
2. Variant of rheumatoid arthritis - splenmegally - neutropenia - RA
Hand Schuller Christian dx
Felty syndrome
Burkitt lymphoma
NF1
3. Burkitts c::myc is on 8 - IG heavy chain is on 14
PIG A
8:14
APC
Hurthle cell
4. Aka acute disseminated langerhans cell histiocytosis - aggressive - usually fatal - kids hepatosplenomegaly - LAD - pancytopenia - pulmonary involvement - recurrent infections
Letterer Siwe dx
Tay Sachs dx
Von Gierke dx
11:22
5. Hereditary nonpolyposis colon cancer - DNA repair genes messed up
Lynch syndrome
Bax
Clue cell
Huntington dx
6. Metastatic stomach CA to ovary
Hirschsprung dx
Heberden nodes
Klinefelter syndrome
Krukenberg tumor
7. Associated with breast alone (isn't one of these associated with prostate? Check)
Whipple dx
Heberden nodes
Bowen dx
BRCA2
8. Infectious disorder - caused postencephalitic parkinsonism
Munro abscesses
Peyronie dx
Von economo encephalitis
Cori dx
9. Pigmented iris hamartoma seen in neurofibromatosis
Lisch nodule
Gaucher dx
Foamy histiocyte
Gerstmann Straussler
10. Deficient a1 -4 glucosidase - accumulation of glycogen in liver - heart - skeletal muscle - cardiomegaly - muscle hypotonia - spelnomegaly - intractable hypoglycemia - death from cardiorespiratory failure before age 3
Whipple triad
Pompe dx
Lesch Nyhan syndrome
Waldenstrom Macroglobulinemia
11. Aka hereditary hemorrhagic telangectasia - telangectasias in skin and mucous membranes - epistaxis - GI bleeds
Cori dx
Orphan annie nuclei
Marfan syndrome
Osler Weber Rendu syndrome
12. Tumor suppressor mutated in Von Recklinhousen
8:14
Wegener granulomatosis
NF1
Hfe gene
13. Deficient sphingomyelinase - accumulation of sphingomyelin in phagocytes - foamy histiocytes in liver - spleen - lymph nodes - skin - hepatosplenomegaly - anemia fever - occasional neuro degeneration - half have cherry red spot macula
Albers SCHonberg dx
Felty syndrome
Starry sky appearance
Niemann Pick dx
14. On lymph node biopsy - seen with Burkitt lymphoma
Peutz Jeghers syndrome
Marfan syndrome
Starry sky appearance
Gaucher dx
15. Aka lentigo maligna - precursor to lentigo maligna melanoma
Hutchinson freckle
Starry sky appearance
Ewing sarcoma
Langhans giant cell
16. Gene product facilitates apoptosis
Chediak Higashi syndrome
Bax
Rouleaux formation
Klinefelter syndrome
17. Small round eosinophilic masses found in dieing hepatocytes often containing chromatin remnants seen in viral hepatitis
Bernard Soulier dx
Birbeck granule
Councilman body
Wilms tumor
18. Mesangial matrix material acculmulations seen in nodular glomerulosclerosis seen in diabetic nephropathy
Berger dx
Plummer dx
Kimmelstiel Wilson nodules
Beriberi
19. Chromosome 19 - allele common in alzheimers
Sheehan syndrome
Whipple triad
E4 allele of apoprotein E
Kimmelsteil Wilson dx
20. Primary aldosteronism
Hashimoto thyroiditis
Addison disease
Conn syndrome
Paget dx of bone
21. Modest elevated serum unconj bilirubin - due to decreased uptake by liver cells and reduced activity of glucuronyl transferase
E4 allele of apoprotein E
Gilbert syndrome
DiGeorge syndrome
Huntington dx
22. Vaginal epithelial cell with stippled appearance due to adherent coccobacilli
Clue cell
Rb gene
Zenker diverticulum
Wermer syndrome
23. Aka velocardiofacial syndrome and CATCH 22 syndrome - micro deletion of 22q11 - Cardiac abnormalities - Abnormal facies - T cell deficit due to thymic hypoplasia - Cleft palate - Hypocalcemia due to hypoparathyroidism - from poor development of 3rd a
Wiskott Aldrich syndrome
Sturge Weber syndrome
Graves dx
DiGeorge syndrome
24. B Thalassemia major
Alport syndrome
Btk gene
Mediterranean anemia or Cooley Anemia
Pancoast tumor
25. Also seen in urine of MM - stacks of RBCs - will have high ESR
Reiter syndrome
Potter sequence
Wegener granulomatosis
Rouleaux formation
26. Appears as multiple wart - like lesions resembling condyloma accuminatum
Waterhouse Friderichsen syndrome
Bowenoid papulosis
Niemann Pick dx
Hurthle cell
27. Radiologic appearance of periostium in bone tumors
Whipple dx
Codman triangle
McArdle syndrome
Virchow node
28. Aneurysm at small artery bifurcations
Charcot Bouchard aneurysm
Kartagener syndrome
Gardner syndrome
Rb gene
29. Intra::alveolar hemosiderin - laden macrophages caused by RBCs from capillary rupture 2* to pulmonary HTN
Wiskott Aldrich syndrome
Kimmelstiel Wilson nodules
Heart failure cells
Negri bodies
30. Paracentric inversion or translocation with 17 associated with papillary thyroid CA
Reinke crystal
HLA B27 antigen
Chromosome 10
Paget dx of vulva
31. DsDNA antibodies and Sm Smith antigen = highly specific for SLE
ANAs in SLE
Reiter syndrome
Councilman body
15:17
32. Deficient fibrillin (constituent of microfibrils) - arachnodactyly - ectopia lentis - aortic aneurysm - mitral valve prolapsed
Addison disease
Stein Leventhal syndrome
Marfan syndrome
GNAS1
33. Hemihypertrophy - macroglossia - organomegaly - neonatal hypoglycemia - various embryonal tumors - deleted WT 2 gene
Hfe gene
N
Beckwith Weidemann syndrome
Names of Vitamins
34. Sphingomyelin containing phagocytes seen in Niemman::Pick dx in liver - spleen - lymph nodes and skin
Fabry dx
Paget dx of vulva
Rotor syndrome
Foamy histiocyte
35. Deficient glucose -6- phosphatase - accumulation of glycogen in liver and kidney - hepatomegaly - hypoglycemia
GNAS1
Von Gierke dx
Orphan annie nuclei
Lynch syndrome
36. Variant of rheumatoid arthritis - aka juvenile rheumatoid arthritis
Von Hippel Lindau dx
ANAs in SLE
Ras oncogenes
Still disease
37. Aggressive B- cell lymphoma - EBV - starry sky appearance - c myc
Burkitt lymphoma
Lisch nodule
Dubin Johnson syndrome
Hutchinson freckle
38. X linked - aka immunodeficiency with thrombocytopenia and eczema - total immunoglobulins often normal - recurrent infections
Sturge Weber syndrome
8:14
Gardner syndrome
Wiskott Aldrich syndrome
39. Aka trisomy 13 - mental retardation - microcephaly - micropthalmia - brain abnormalities - cleft lip/palate - polydactyly - rockerbottom feet - congenital heart dx
Huntington dx
Patau syndrome
Paget dx of breast
Hutchinson freckle
40. Different in that it is the primary disorder - recurrent vasospasm of small arteries and venules - pallor - cyanosis - fingers and toes - young healthy women
Nelson syndrome
PIG A
Heart failure cells
Raynaud disease
41. Aka allergic granulomatous angiitis - necrotizing vasculitis - variant of polyarteritis nodosa - involves pulmonary vasculature - peripheral eosinophilia - and asthma
Bouchard nodes
Libman Sacks endocarditis
Peutz Jeghers syndrome
Churg Strauss syndrome
42. Primary adrenal failure
Wegener granulomatosis
Waldenstrom Macroglobulinemia
Kimmelsteil Wilson dx
Addison disease
43. Aka pituitary cachexia - generalized panhypopituitarism
Kayser Fleischer ring
Heberden nodes
Btk gene
Simmonds dx
44. Aka pulseless dx - inflammation and stenosis of medium and large sized arteries - often aortic arch thus aortic arch syndrome
Osler Weber Rendu syndrome
Names of Vitamins
Cri du chat syndrome
Takayasu arteritis
45. Similar to paget breast - sometimes related to underlying adenoCA of sweat glands
Kawasaki dx
Bax
Whipple dx
Paget dx of vulva
46. Epithelial cells with eosinophilc granular cytoplasm seen in hashimoto
Reed Sternburg cell
Hurthle cell
Takayasu arteritis
Arthus reaction
47. Esophageal diverticulum just above upper esoph sphincter
Kawasaki dx
Ferruginous body
Zenker diverticulum
ret PTC
48. Located on xsome 6 - mutation here = hereditary hemochromatosis
Zenker diverticulum
Hfe gene
ret
Werdnig Hoffman syndrome
49. Malignant lymphoma with features resembling inflammatory disorder - young men - Reed Sternburg cells
Gilbert syndrome
Hodgkin dx
Hirschsprung dx
Chediak Higashi syndrome
50. Hemorrhagic urticaria of extensor surgaces of arms - legs - and buttocks - with fever - arthralgias - and GI renal involvement similar to IgA nephropathy - associated with URIs
Paget dx of breast
Signet ring cell
Tay Sachs dx
Henoch Schonlein Purpura