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USMLE Brs Pathology Vocab
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health-sciences
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usmle
Instructions:
Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Osteophytes at DIP joints
Heberden nodes
Lynch syndrome
Angelman syndrome
Arnold Chiari formation
2. Seen in CLL - leukemic B- cells that are fragile
Smudge cells
Arnold Chiari formation
Heart failure cells
9:22
3. Autosomal dominant - fatal - progressive degeneration of striatum and frontal cortex with neuronal depletion and gliosis
Zenker diverticulum
Bax
Reiter syndrome
Huntington dx
4. Thiamine deficiency - cerebral dysfunction - aka alcoholic encephalopathy - hemorrhagic lesions in the mamillary bodies - confusion - ataxia - ophthalmoplegia - and memory loss plus confabulation p 105 and p115
Kawasaki dx
DiGeorge syndrome
Bernard Soulier dx
Wernicke Korsakoff syndrome
5. Associated with Wegener granulomatosis
Dubin Johnson syndrome
C ANCA
Mediterranean anemia or Cooley Anemia
Kayser Fleischer ring
6. Subcutaneous fibrosis of dorsum of penis
Graves dx
Prader willi syndrome
Peyronie dx
Zenker diverticulum
7. Dysplastic cell seen in HPV
Koilocyte
Fabry dx
GNAS1
Tay Sachs dx
8. Peripheral neuropathy - atrophy of muscles - wet - high output cardiac failure - DCM - AV shunting - hypervolemia
Wermer syndrome
Gerstmann Straussler
Letterer Siwe dx
Dry beriberi
9. Impaired tubular reabsorption of tryptophan - pellagra::like manifestations
Ras oncogenes
Hartnup dx
Sheehan syndrome
Kimmelstiel Wilson nodules
10. Myc :: neuroblastoma amplicatiion correlates inversely with degree of differentiation
Paget dx of breast
Sipple syndrome
N
Koilocyte
11. Associated with 90% cases of ankylosing spondylitis - common in rheumatoid arthritis
Hunter syndrome
HLA B27 antigen
Sheehan syndrome
Kimmelsteil Wilson dx
12. Autosomal dominant - numerous adenomatous polyps along with osteomas and soft tissue tumors
Patau syndrome
Ras oncogenes
Hurler syndrome
Gardner syndrome
13. Pituitary insufficiency post - partum - low TSH ACTH
Sheehan syndrome
Zenker diverticulum
Kimmelstiel Wilson nodules
Wermer syndrome
14. Gene mutated in achondroplasia (most common form of dwarfism) - located at 4p16.3
Angelman syndrome
McArdle syndrome
FGFR3
Sturge Weber syndrome
15. Abnormal WT 1 gene - intersexual disorders - nephropathy - wilms tumor
Gerstmann Straussler
Bouchard nodes
Denys Drash syndrome
ANAs in SLE
16. Autoimmune hypothyroid - hurthle cells common
Osler Weber Rendu syndrome
Edwards syndrome
Hashimoto thyroiditis
Clue cell
17. Aka infantile progressive spinal muscular atrophy - autosomal recessive - LMN disease - infants
Signet ring cell
Brushfield spots
Kartagener syndrome
Werdnig Hoffman syndrome
18. Deficient glucose -6- phosphatase - accumulation of glycogen in liver and kidney - hepatomegaly - hypoglycemia
Kartagener syndrome
Zenker diverticulum
Von Gierke dx
Bouchard nodes
19. Deficient fibrillin (constituent of microfibrils) - arachnodactyly - ectopia lentis - aortic aneurysm - mitral valve prolapsed
C ANCA
Marfan syndrome
Addison disease
Ras oncogenes
20. Aka velocardiofacial syndrome and CATCH 22 syndrome - micro deletion of 22q11 - Cardiac abnormalities - Abnormal facies - T cell deficit due to thymic hypoplasia - Cleft palate - Hypocalcemia due to hypoparathyroidism - from poor development of 3rd a
DiGeorge syndrome
Addison disease
Tay Sachs dx
Sturge Weber syndrome
21. Sphingomyelin containing phagocytes seen in Niemman::Pick dx in liver - spleen - lymph nodes and skin
Goodpasture syndrome
Budd Chiari
Foamy histiocyte
Lynch syndrome
22. Defective cilia - sinusitis - bronchiectasis - situs inversus - sometimes hearing loss and male sterility
Paget dx of breast
Kartagener syndrome
Lynch syndrome
Waldenstrom Macroglobulinemia
23. Triad of ovarian fibroma - ascites - hydrothorax
Meigs syndrome
Turner syndrome
Kartagener syndrome
Paget dx of bone
24. Thrombotic occlusion of major hepatic veins - abnormal pain - jaundice - hepatomegaly - acites - liver failure - assoc with polycythemia vera - hepatocellular CA - and other common neoplasms - may occur as a complication of pregnancy
Budd Chiari
Whipple dx
Marfan syndrome
Sheehan syndrome
25. On lymph node biopsy - seen with Burkitt lymphoma
Waldenstrom Macroglobulinemia
Meigs syndrome
Birbeck granule
Starry sky appearance
26. Infectious disorder - caused postencephalitic parkinsonism
Gerstmann Straussler
Hurler syndrome
Paget dx of vulva
Von economo encephalitis
27. Aka trisomy 13 - mental retardation - microcephaly - micropthalmia - brain abnormalities - cleft lip/palate - polydactyly - rockerbottom feet - congenital heart dx
Call Exner bodies
9:22
Raynaud phenomenon
Patau syndrome
28. Aka IgA nephropathy - deposition of IgA in mesangium - benign recurrent hematuria in kids following infection
Hodgkin dx
Klinefelter syndrome
Bense Jones protein
Berger dx
29. Aka mucocutaneous lymph node syndrome - acute self - limited - infants and young kids - acute necrotizing vasculitis of small and medium vessels - fever hemorrhagic edema of conjunctivae - lips and oral mucosa - and cervical LAD - can cause coronary
Hurthle cell
Cori dx
Addison disease
Kawasaki dx
30. Urethritis - conjunctivitis - arthritis - associated with venereal or intestinal infection
Reiter syndrome
15:17
Bernard Soulier dx
Hurler syndrome
31. Seen in Down synd - small white spots on periphery of iris
Patau syndrome
Kimmelstiel Wilson nodules
Binswanger dx
Brushfield spots
32. Seen in granuloma inguinale - multiple organisms filling large histiocytes
Libman Sacks endocarditis
Waterhouse Friderichsen syndrome
Negri bodies
Donovan bodies
33. Eosinophilic intracytoplasmic inclusions in hippocampus and purkinje cells seen in rabies infection
Codman triangle
Peyronie dx
Bense Jones protein
Negri bodies
34. Tumor suppressor mutated in wilms tumor
Beriberi
GNAS1
Simmonds dx
WT1 and WT2
35. Radiologic appearance of periostium in bone tumors
Chromosome 10
Codman triangle
Wermer syndrome
Gerstmann Straussler
36. Ovarian tumor resembling bladder transitional epith
Brenner tumor
Kayser Fleischer ring
Libman Sacks endocarditis
Hodgkin dx
37. Similar to paget breast - sometimes related to underlying adenoCA of sweat glands
APC
Rouleaux formation
Paget dx of vulva
Wiskott Aldrich syndrome
38. Associated with papillary thyroid CA
ret PTC
Bcl2
Wilson dx
Felty syndrome
39. Similar to Dubin Johnson with no black liver
Rotor syndrome
Churg Strauss syndrome
Wernicke Korsakoff syndrome
Whipple dx
40. Follicular lymphoma IG heavy chain on 14 - bcl -2 oncogene on 18
Gaucher dx
14:18
Brushfield spots
Sipple syndrome
41. Hemangioblastoma or cavernous hemangioma of cerebellum - brainstem or retina - adenomas - cysts in liver - kidney - pancreas - and other organs - increased renal cell CA - gene = short arm of chromosome 3
Von Hippel Lindau dx
Still disease
Kimmelstiel Wilson nodules
Ewing sarcoma
42. Nystagmus - intention tremor - scanning speech - seen in MS
ret PTC
Gerstmann Straussler
Hirschsprung dx
Charcot triad
43. Aka congenital megacolon - dilation of colon due to absence of ganglion cells
Edwards syndrome
Hirschsprung dx
Reiter syndrome
Arthus reaction
44. Nuclei arranged in horseshoe - shaped pattern about periphery of cell - characteristic of but not specific for granulomatous TB (as opposed to a foreign body giant cell that has scattered nuclei)
Langhans giant cell
Kartagener syndrome
Hutchinson freckle
Patau syndrome
45. Primary aldosteronism
Lambert Eaton syndrome
Reiter syndrome
Conn syndrome
Kawasaki dx
46. Deficient hexosaminidase A - GM2 ganglioside accumulation - especially in neurons - CNS degeneration - mental/motor deterioration - blindness - cherry red spot on macula - death by 4 years of age
Beriberi
Osler Weber Rendu syndrome
Tay Sachs dx
Wilson dx
47. Also seen in urine of MM - stacks of RBCs - will have high ESR
Tay Sachs dx
Call Exner bodies
Rouleaux formation
E4 allele of apoprotein E
48. Gene product facilitates apoptosis
Werdnig Hoffman syndrome
Paget dx of breast
Bax
WT1 and WT2
49. Philadelphia chromosome - CML bcr abl fusion c - abl on 9 - bcr on 22
9:22
Von Gierke dx
Clue cell
Smudge cells
50. Ring of copper deposited around iris seen in Wilson
Kayser Fleischer ring
Kimmelsteil Wilson dx
Wilson dx
Beriberi
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