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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Hereditary nephritis associated with nerve deafness and ocular disorders - mutation in gene for the a5 chain of type IV collagen






2. Thiamine deficiency - cerebral dysfunction - aka alcoholic encephalopathy - hemorrhagic lesions in the mamillary bodies - confusion - ataxia - ophthalmoplegia - and memory loss plus confabulation p 105 and p115






3. Aka mucocutaneous lymph node syndrome - acute self - limited - infants and young kids - acute necrotizing vasculitis of small and medium vessels - fever hemorrhagic edema of conjunctivae - lips and oral mucosa - and cervical LAD - can cause coronary






4. B1 thiamine - B2 riboflavin - B3 niacin - B6 pyridoxine - B12 cobalamin - C ascorbic acid - D calciferol - E a::tocopherol






5. Aka pulseless dx - inflammation and stenosis of medium and large sized arteries - often aortic arch thus aortic arch syndrome






6. Aka polycystic ovary syndrome - young women - amenorrhea - infertility - obesity - hirsutism






7. Area of focal interstitial myocardial inflammation characterized by fragmented collagen and fibrinoid material - by large cells (Anitschkow myocytes) and occasional multinucleated giant cells (Aschoff cells)






8. Also seen in urine of MM - stacks of RBCs - will have high ESR






9. Malignant lymphoma with features resembling inflammatory disorder - young men - Reed Sternburg cells






10. Asbestosis - yellow - brown - rod shaped body with clubbed ends - stain with Prussian blue






11. Variant of rheumatoid arthritis - splenmegally - neutropenia - RA






12. Gene product inhibits apoptosis






13. Autosomal recessive - neutropenia - albinism - cranial and peripheral neuropathy - tendency to develop repeated infections - abnormal WBCs (abnormal mictotubul formation and large cytoplasmic granules = lysosomes)






14. Aka superior sulcus tumor - seen in bronchogenic CA - often with Horner's






15. DsDNA antibodies and Sm Smith antigen = highly specific for SLE






16. Deficient hypoxanthine::guanine phosphoribosyltransferase (HGPRT) - low purine metabolism - high uric acid - thus gout - mental retardation - choreoathetosis - spasticity - self mutilation - aggressiveness






17. Seen in Down synd - small white spots on periphery of iris






18. 45 XO - female hypogonadism - hypothyroid - short - webbed neck - 1* amenorrhea p52






19. Primary adrenal failure






20. Seen in CLL - leukemic B- cells that are fragile






21. Aka IgA nephropathy - deposition of IgA in mesangium - benign recurrent hematuria in kids following infection






22. Acute promyelocytic leukemia PML gene on 15 and RARa on 17






23. Development of large pituitary adenomas following bilat adrenalectomy






24. Gene product facilitates apoptosis






25. Aka pituitary cachexia - generalized panhypopituitarism






26. Ring of copper deposited around iris seen in Wilson






27. Iron deficient anemia associated with upper::esophageal web






28. Downward displacement of cerebellar tonsils and medulla through foramen magnum






29. Deficient fibrillin (constituent of microfibrils) - arachnodactyly - ectopia lentis - aortic aneurysm - mitral valve prolapsed






30. 2/neu :: oncogene (aka c - erbB2) - in breast cancer = poor prognosis






31. Catastrophic adrenal insuff and vascular collapse - hemorrhagic necrosis of adrenal cortex






32. Oligohydramnios causes fetus to be smashed






33. Hereditary nonpolyposis colon cancer - DNA repair genes messed up






34. Peripheral neuropathy - atrophy of muscles - wet - high output cardiac failure - DCM - AV shunting - hypervolemia






35. Seen in granuloma inguinale - multiple organisms filling large histiocytes






36. Polyostotic fibrous dysplasia - precocious puberty - caf






37. Aka angiokeratoma corporis diffusum universal - deficient a::galactosidase A - accumulate ceramide trihexoside - skin lesions angiokeratomas - fever - burning pain in extremities - cardiovascular and cerebrovascular involvement - death as adult by re






38. Diffuse nodular diabetic glomerulosclerosis






39. Small follicles filled with eosinophilic secretion - diagnostic feature of granulose cell tumor






40. Appears as multiple wart - like lesions resembling condyloma accuminatum






41. Nystagmus - intention tremor - scanning speech - seen in MS






42. Located on xsome 6 - mutation here = hereditary hemochromatosis






43. Aka allergic granulomatous angiitis - necrotizing vasculitis - variant of polyarteritis nodosa - involves pulmonary vasculature - peripheral eosinophilia - and asthma






44. Variant of rheumatoid arthritis - aka juvenile rheumatoid arthritis






45. Intracytoplasmic inclusions seen in leydig cell tumors p283






46. Tennis racket shaped cytoplasmic inclusion seen in langerhans cells (so also seen in langerhan cell histiocytosis)






47. Hamartomatous polyps in colon and small intest - freckles on lips - hands - genitalia - higher incidence of adeno CA of colon and other malignancies - stomach - breast - ovaries






48. Similar to Dubin Johnson with no black liver






49. Mucinous cell - characteristic of stomach CA met to ovary (krukenberg tumor)






50. Deficient glucose -6- phosphatase - accumulation of glycogen in liver and kidney - hepatomegaly - hypoglycemia