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Test your basic knowledge |
USMLE Brs Pathology Vocab
Start Test
Study First
Subjects
:
health-sciences
,
usmle
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Osteophytes at PIP joints
E4 allele of apoprotein E
Plummer Vinson syndrome
Bouchard nodes
Signet ring cell
2. Hereditary nephritis associated with nerve deafness and ocular disorders - mutation in gene for the a5 chain of type IV collagen
McCune Albright syndrome
Alport syndrome
Gardner syndrome
Orphan annie nuclei
3. Oncogenes that code for p21 proteins which are membrane signalers
Churg Strauss syndrome
Ras oncogenes
McCune Albright syndrome
Charcot Bouchard aneurysm
4. Gene mutated in achondroplasia (most common form of dwarfism) - located at 4p16.3
Prader willi syndrome
Hutchinson freckle
Whipple dx
FGFR3
5. Mucopolysaccharidosis - deficient a L iduronidase - accumulations of heparin sulfate and dermatan sulfate in heart - brain - liver - and other organs - progressive - hepatosplenomagaly - dwarfism - gargoyle - like facies - stubby fingers - corneal cl
Hurler syndrome
Gilbert syndrome
Reiter syndrome
Kimmelsteil Wilson dx
6. Aka trisomy 13 - mental retardation - microcephaly - micropthalmia - brain abnormalities - cleft lip/palate - polydactyly - rockerbottom feet - congenital heart dx
Btk gene
Patau syndrome
Call Exner bodies
14:18
7. Impaired tubular reabsorption of tryptophan - pellagra::like manifestations
Hartnup dx
Still disease
Burkitt lymphoma
Heberden nodes
8. Aka superior sulcus tumor - seen in bronchogenic CA - often with Horner's
Hfe gene
Councilman body
Pancoast tumor
Berger dx
9. Minute neutrophilic abscesses found within parakeratotic stratum corneum in psoriasis
Angelman syndrome
Hurthle cell
GNAS1
Munro abscesses
10. Aka acute disseminated langerhans cell histiocytosis - aggressive - usually fatal - kids hepatosplenomegaly - LAD - pancytopenia - pulmonary involvement - recurrent infections
Heart failure cells
APC
Paget dx of breast
Letterer Siwe dx
11. Deficient glucose -6- phosphatase - accumulation of glycogen in liver and kidney - hepatomegaly - hypoglycemia
Von Gierke dx
Ras oncogenes
Fanconi syndrome
Sipple syndrome
12. X linked - aka immunodeficiency with thrombocytopenia and eczema - total immunoglobulins often normal - recurrent infections
Bense Jones protein
Kartagener syndrome
Wiskott Aldrich syndrome
Churg Strauss syndrome
13. Clear cell renal tumor seen in kids
Wilms tumor
14:18
Names of Vitamins
BRCA1
14. Aka pituitary cachexia - generalized panhypopituitarism
Simmonds dx
Turcot syndrome
Beckwith Weidemann syndrome
Reiter syndrome
15. Hemangioblastoma or cavernous hemangioma of cerebellum - brainstem or retina - adenomas - cysts in liver - kidney - pancreas - and other organs - increased renal cell CA - gene = short arm of chromosome 3
Raynaud disease
Nelson syndrome
Von Hippel Lindau dx
Kayser Fleischer ring
16. B Thalassemia major
Bax
Peutz Jeghers syndrome
Mediterranean anemia or Cooley Anemia
Kimmelstiel Wilson nodules
17. Thiamine deficiency - cerebral dysfunction - aka alcoholic encephalopathy - hemorrhagic lesions in the mamillary bodies - confusion - ataxia - ophthalmoplegia - and memory loss plus confabulation p 105 and p115
N
Wernicke Korsakoff syndrome
Bense Jones protein
Gerstmann Straussler
18. Aka osteopetrosis - marble bone dx - dense skeleton - failure of osteoclastic activity
Albers SCHonberg dx
Kimmelsteil Wilson dx
Mediterranean anemia or Cooley Anemia
Negri bodies
19. DsDNA antibodies and Sm Smith antigen = highly specific for SLE
Angelman syndrome
Beckwith Weidemann syndrome
Bcl2
ANAs in SLE
20. Tumor suppressor mutated in wilms tumor
Wermer syndrome
WT1 and WT2
8:14
Brown tumor
21. Catastrophic adrenal insuff and vascular collapse - hemorrhagic necrosis of adrenal cortex
Pompe dx
Wiskott Aldrich syndrome
Lesch Nyhan syndrome
Waterhouse Friderichsen syndrome
22. Seen in urine of patients with multiple myeloma - Ig light chain either k or l
Bense Jones protein
Heart failure cells
Turner syndrome
Waldenstrom Macroglobulinemia
23. Aka IgA nephropathy - deposition of IgA in mesangium - benign recurrent hematuria in kids following infection
Gardner syndrome
ret
Berger dx
Plummer dx
24. Pituitary insufficiency post - partum - low TSH ACTH
Kayser Fleischer ring
BRCA2
Sheehan syndrome
Councilman body
25. Development of large pituitary adenomas following bilat adrenalectomy
Dry beriberi
Nelson syndrome
Felty syndrome
Prader willi syndrome
26. Aka allergic granulomatous angiitis - necrotizing vasculitis - variant of polyarteritis nodosa - involves pulmonary vasculature - peripheral eosinophilia - and asthma
Turcot syndrome
Smudge cells
Kawasaki dx
Churg Strauss syndrome
27. Defective cilia - sinusitis - bronchiectasis - situs inversus - sometimes hearing loss and male sterility
McArdle syndrome
Bowen dx
Kartagener syndrome
Beckwith Weidemann syndrome
28. Deficient hexosaminidase A - GM2 ganglioside accumulation - especially in neurons - CNS degeneration - mental/motor deterioration - blindness - cherry red spot on macula - death by 4 years of age
Kawasaki dx
Dubin Johnson syndrome
Ferruginous body
Tay Sachs dx
29. Small round eosinophilic masses found in dieing hepatocytes often containing chromatin remnants seen in viral hepatitis
Smudge cells
Sipple syndrome
Reidel thyroiditis
Councilman body
30. At least 2 X and one Y - hypogonadism - tall - gynecomastia - low testosterone - high pituitary gonadotropins - infertility -
Sipple syndrome
Alport syndrome
Kimmelstiel Wilson nodules
Klinefelter syndrome
31. Peripheral neuropathy - atrophy of muscles - wet - high output cardiac failure - DCM - AV shunting - hypervolemia
Dry beriberi
Brushfield spots
Kartagener syndrome
8:14
32. Acute inflammatory demyelinating dx primarily involving peripheral nerves
N
GNAS1
Niemann Pick dx
Guillain Barre syndrome
33. Retinoblastoma on chromosome 13
Rb gene
ret PTC
Ferruginous body
Rouleaux formation
34. Combination of hyperthyroidism - nodular goiter - absence of exophthalmos
Rouleaux formation
Plummer dx
Turner syndrome
Bcl2
35. Also seen in urine of MM - stacks of RBCs - will have high ESR
Rouleaux formation
Henoch Schonlein Purpura
Peutz Jeghers syndrome
Lynch syndrome
36. Similar to Hurler - deficient L iduronosulfate sulfatase - accumulations of heparin sulfate and dermatan sulfate - hepatospenomegaly - micrognathia - retinal degeneration - joint stiffness - mental retardation - cardiac lesions
Hunter syndrome
Lambert Eaton syndrome
Von Gierke dx
Huntington dx
37. Myc :: neuroblastoma amplicatiion correlates inversely with degree of differentiation
Clue cell
N
Von Gierke dx
Heart failure cells
38. Associated with breast alone (isn't one of these associated with prostate? Check)
BRCA2
Chromosome 10
Hutchinson freckle
Lynch syndrome
39. Port wine stain on face - ipsilateral glaucoma - vascular lesions of ocular choroidal tissue - extensive hemangiomatous involvement of meninges
Sturge Weber syndrome
Crigler Najjar syndrome
Simmonds dx
Bowenoid papulosis
40. Sphingomyelin containing phagocytes seen in Niemman::Pick dx in liver - spleen - lymph nodes and skin
Foamy histiocyte
Burkitt lymphoma
Zenker diverticulum
Birbeck granule
41. Paraneoplastic synd looks like myasthenia gravis - often small cell lung CA
Lambert Eaton syndrome
Orphan annie nuclei
Peutz Jeghers syndrome
Rotor syndrome
42. Aka osteitis deformans - increased osteoclastic and osteoblastic activity
Kartagener syndrome
Paget dx of bone
GNAS1
Von Gierke dx
43. Seen in insulinoma - episodic hyperinsulinemia and hypoglycemia - CNS dysfunction - reversal of CNS probs with administration of glucose
Von Hippel Lindau dx
Whipple triad
Raynaud disease
Henoch Schonlein Purpura
44. Severe unconj hyperbilirubinemia due to deficient glucuronyl transferase
Berger dx
Turcot syndrome
Crigler Najjar syndrome
Reidel thyroiditis
45. Hemorrhagic urticaria of extensor surgaces of arms - legs - and buttocks - with fever - arthralgias - and GI renal involvement similar to IgA nephropathy - associated with URIs
Gaucher dx
BRCA1
Conn syndrome
Henoch Schonlein Purpura
46. This comes in a wet variety and a dry one - they are both Vit B1 thiamine deficiency
Nelson syndrome
Bax
Beriberi
Plummer Vinson syndrome
47. Autosomal recessive - unusually large platelets - lack of 'GPIb IX V'
Von Hippel Lindau dx
Guillain Barre syndrome
Bernard Soulier dx
Patau syndrome
48. Thrombotic occlusion of major hepatic veins - abnormal pain - jaundice - hepatomegaly - acites - liver failure - assoc with polycythemia vera - hepatocellular CA - and other common neoplasms - may occur as a complication of pregnancy
Felty syndrome
Klinefelter syndrome
Budd Chiari
Von Recklinhousen dx
49. 2/neu :: oncogene (aka c - erbB2) - in breast cancer = poor prognosis
HER
Reiter syndrome
Fabry dx
Wilson dx
50. Single erythematous plaque on shaft of penis or scrotum
Von Gierke dx
8:14
NF1
Bowen dx