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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Nuclei arranged in horseshoe - shaped pattern about periphery of cell - characteristic of but not specific for granulomatous TB (as opposed to a foreign body giant cell that has scattered nuclei)






2. Aka polycystic ovary syndrome - young women - amenorrhea - infertility - obesity - hirsutism






3. Ovarian tumor resembling bladder transitional epith






4. Deficient hypoxanthine::guanine phosphoribosyltransferase (HGPRT) - low purine metabolism - high uric acid - thus gout - mental retardation - choreoathetosis - spasticity - self mutilation - aggressiveness






5. Hereditary nonpolyposis colon cancer - DNA repair genes messed up






6. Nystagmus - intention tremor - scanning speech - seen in MS






7. Myc :: neuroblastoma amplicatiion correlates inversely with degree of differentiation






8. Aka neurofibromatosis - neurofibromas in skin - schwannomas of CN VIII - caf






9. Mesangial matrix material acculmulations seen in nodular glomerulosclerosis seen in diabetic nephropathy






10. Hamartomatous polyps in colon and small intest - freckles on lips - hands - genitalia - higher incidence of adeno CA of colon and other malignancies - stomach - breast - ovaries






11. Severe unconj hyperbilirubinemia due to deficient glucuronyl transferase






12. Triad of ovarian fibroma - ascites - hydrothorax






13. Defective in x- linked brutons agammaglobulinemia - B- cell tyrosine kinase






14. Polyostotic fibrous dysplasia - precocious puberty - caf






15. Aka hereditary hemorrhagic telangectasia - telangectasias in skin and mucous membranes - epistaxis - GI bleeds






16. Aneurysm at small artery bifurcations






17. Autoimmune thyroiditis - hyperthyroid - exophthalmos - increased in HLA DR3 and HLA B8 pos people






18. Aka IgA nephropathy - deposition of IgA in mesangium - benign recurrent hematuria in kids following infection






19. Oligohydramnios causes fetus to be smashed






20. 5p chromosome deletion - severe mental retardation - microcephaly - catlike cry - low birth weight - round face - hypertelorism (wide eyes)






21. Seen in hyperacute rejection - = acute inflammation - fibrinoid necrosis of small vessels - and extensive thrombosis






22. Variant of rheumatoid arthritis - aka juvenile rheumatoid arthritis






23. Associated with Wegener granulomatosis






24. Oncogenes that code for p21 proteins which are membrane signalers






25. Aka velocardiofacial syndrome and CATCH 22 syndrome - micro deletion of 22q11 - Cardiac abnormalities - Abnormal facies - T cell deficit due to thymic hypoplasia - Cleft palate - Hypocalcemia due to hypoparathyroidism - from poor development of 3rd a






26. Urethritis - conjunctivitis - arthritis - associated with venereal or intestinal infection






27. Mucopolysaccharidosis - deficient a L iduronidase - accumulations of heparin sulfate and dermatan sulfate in heart - brain - liver - and other organs - progressive - hepatosplenomagaly - dwarfism - gargoyle - like facies - stubby fingers - corneal cl






28. Variant of rheumatoid arthritis - splenmegally - neutropenia - RA






29. Non::neoplastic tumor like masses - fibrous replacement of resorbed bone






30. Seen in granuloma inguinale - multiple organisms filling large histiocytes






31. Associated with papillary thyroid CA






32. Aka angiokeratoma corporis diffusum universal - deficient a::galactosidase A - accumulate ceramide trihexoside - skin lesions angiokeratomas - fever - burning pain in extremities - cardiovascular and cerebrovascular involvement - death as adult by re






33. Chromosome 19 - allele common in alzheimers






34. Aggressive B- cell lymphoma - EBV - starry sky appearance - c myc






35. Similar to Dubin Johnson with no black liver






36. 2/neu :: oncogene (aka c - erbB2) - in breast cancer = poor prognosis






37. Adenomatous polyps with tumors of CNS






38. Pituitary insufficiency post - partum - low TSH ACTH






39. Lots of tumors - breast CA - soft tissue sarc - brain tumors - leukemias - has loss of p53 tumor suppressor gene






40. Protooncogene mutated in medulary thyroid CA (MENII)






41. Associated with 90% cases of ankylosing spondylitis - common in rheumatoid arthritis






42. Primary adrenal failure






43. Aka pituitary cachexia - generalized panhypopituitarism






44. Deficient fibrillin (constituent of microfibrils) - arachnodactyly - ectopia lentis - aortic aneurysm - mitral valve prolapsed






45. Gene product inhibits apoptosis






46. Deficient sphingomyelinase - accumulation of sphingomyelin in phagocytes - foamy histiocytes in liver - spleen - lymph nodes - skin - hepatosplenomegaly - anemia fever - occasional neuro degeneration - half have cherry red spot macula






47. Gene product facilitates apoptosis






48. Intra::alveolar hemosiderin - laden macrophages caused by RBCs from capillary rupture 2* to pulmonary HTN






49. Paraneoplastic synd looks like myasthenia gravis - often small cell lung CA






50. Asbestosis - yellow - brown - rod shaped body with clubbed ends - stain with Prussian blue