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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Malignant lymphoma with features resembling inflammatory disorder - young men - Reed Sternburg cells






2. Aka polycystic ovary syndrome - young women - amenorrhea - infertility - obesity - hirsutism






3. Mutation = paroxysmal nocturnal hemoglobinuria






4. Seen in hyperacute rejection - = acute inflammation - fibrinoid necrosis of small vessels - and extensive thrombosis






5. Adenomatous polyps with tumors of CNS






6. Manifestation of lymphplasmocytic lymphoma - B cell neoplasm






7. Nuclei arranged in horseshoe - shaped pattern about periphery of cell - characteristic of but not specific for granulomatous TB (as opposed to a foreign body giant cell that has scattered nuclei)






8. Catastrophic adrenal insuff and vascular collapse - hemorrhagic necrosis of adrenal cortex






9. Infectious disorder - caused postencephalitic parkinsonism






10. Autosomal recessive - hepatitis - accumulation of copper due to transport problem - low ceruloplasmin seen - kayser fleischer rings in eyes






11. Radiologic appearance of periostium in bone tumors






12. Aka lentigo maligna - precursor to lentigo maligna melanoma






13. X linked - aka immunodeficiency with thrombocytopenia and eczema - total immunoglobulins often normal - recurrent infections






14. Deficient hexosaminidase A - GM2 ganglioside accumulation - especially in neurons - CNS degeneration - mental/motor deterioration - blindness - cherry red spot on macula - death by 4 years of age






15. Burkitts c::myc is on 8 - IG heavy chain is on 14






16. Aka pulseless dx - inflammation and stenosis of medium and large sized arteries - often aortic arch thus aortic arch syndrome






17. Tumor suppressor mutated in Von Recklinhousen






18. Follicular lymphoma IG heavy chain on 14 - bcl -2 oncogene on 18






19. Triad of ovarian fibroma - ascites - hydrothorax






20. Eosinophilic intracytoplasmic inclusions in hippocampus and purkinje cells seen in rabies infection






21. Osteophytes at DIP joints






22. Development of large pituitary adenomas following bilat adrenalectomy






23. Aka pituitary cachexia - generalized panhypopituitarism






24. Aka trisomy 13 - mental retardation - microcephaly - micropthalmia - brain abnormalities - cleft lip/palate - polydactyly - rockerbottom feet - congenital heart dx






25. Autoimmune hypothyroid - hurthle cells common






26. Deficient a1 -4 glucosidase - accumulation of glycogen in liver - heart - skeletal muscle - cardiomegaly - muscle hypotonia - spelnomegaly - intractable hypoglycemia - death from cardiorespiratory failure before age 3






27. Paternal transmission del (15)(q11q13) - hypogonad - hypotonia - mental retardation - behavior probs - uncrontrolled appetite






28. Small round eosinophilic masses found in dieing hepatocytes often containing chromatin remnants seen in viral hepatitis






29. Scheinker syndrome :: prion dx - fatal familial insomnia






30. Similar to paget breast - sometimes related to underlying adenoCA of sweat glands






31. Tumor suppressor common in familial polyposis coli and adenoCA of colon as well as other tumors






32. Aggressive B- cell lymphoma - EBV - starry sky appearance - c myc






33. Deficient fibrillin (constituent of microfibrils) - arachnodactyly - ectopia lentis - aortic aneurysm - mitral valve prolapsed






34. Primary aldosteronism






35. Aka chronic progressive histiocytosis - not as bad as Letterer Siwe






36. Subcutaneous fibrosis of dorsum of penis






37. Aka infantile progressive spinal muscular atrophy - autosomal recessive - LMN disease - infants






38. Hereditary nephritis associated with nerve deafness and ocular disorders - mutation in gene for the a5 chain of type IV collagen






39. Gene mutated in achondroplasia (most common form of dwarfism) - located at 4p16.3






40. Paraneoplastic synd looks like myasthenia gravis - often small cell lung CA






41. Unknown etiology - necrotizing granulomatous vasculitis of small to medium sized vessels of the respiratory tract - kidneys - and other organs - circulating C- ANCAs






42. Urethritis - conjunctivitis - arthritis - associated with venereal or intestinal infection






43. Severe unconj hyperbilirubinemia due to deficient glucuronyl transferase






44. Associated with Wegener granulomatosis






45. Gene product facilitates apoptosis - decreases bcl::2 and increases Bax






46. Chromosome 19 - allele common in alzheimers






47. Appears as multiple wart - like lesions resembling condyloma accuminatum






48. Hemihypertrophy - macroglossia - organomegaly - neonatal hypoglycemia - various embryonal tumors - deleted WT 2 gene






49. Aka superior sulcus tumor - seen in bronchogenic CA - often with Horner's






50. Mutation here causes pseudohypoparathyroidism