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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Aka trisomy 13 - mental retardation - microcephaly - micropthalmia - brain abnormalities - cleft lip/palate - polydactyly - rockerbottom feet - congenital heart dx






2. Occurs in SLE - small vegitations on either or both surfaces of valves






3. Hamartomatous polyps in colon and small intest - freckles on lips - hands - genitalia - higher incidence of adeno CA of colon and other malignancies - stomach - breast - ovaries






4. Gene product facilitates apoptosis






5. Thiamine deficiency - cerebral dysfunction - aka alcoholic encephalopathy - hemorrhagic lesions in the mamillary bodies - confusion - ataxia - ophthalmoplegia - and memory loss plus confabulation p 105 and p115






6. B1 thiamine - B2 riboflavin - B3 niacin - B6 pyridoxine - B12 cobalamin - C ascorbic acid - D calciferol - E a::tocopherol






7. Eczematoid lesion of nipple areola - large cells with clear 'halo like' area - invade epidermis - underlying ductal CA






8. Similar to Dubin Johnson with no black liver






9. Primary adrenal failure






10. 5p chromosome deletion - severe mental retardation - microcephaly - catlike cry - low birth weight - round face - hypertelorism (wide eyes)






11. Autosomal dominant - fatal - progressive degeneration of striatum and frontal cortex with neuronal depletion and gliosis






12. Burkitts c::myc is on 8 - IG heavy chain is on 14






13. Diffuse nodular diabetic glomerulosclerosis






14. Paracentric inversion or translocation with 17 associated with papillary thyroid CA






15. Autosomal recessive - unusually large platelets - lack of 'GPIb IX V'






16. Tumor suppressor mutated in wilms tumor






17. Vaginal epithelial cell with stippled appearance due to adherent coccobacilli






18. Aka polycystic ovary syndrome - young women - amenorrhea - infertility - obesity - hirsutism






19. Defective in x- linked brutons agammaglobulinemia - B- cell tyrosine kinase






20. Minute neutrophilic abscesses found within parakeratotic stratum corneum in psoriasis






21. Manifestation of lymphplasmocytic lymphoma - B cell neoplasm






22. Gene mutated in achondroplasia (most common form of dwarfism) - located at 4p16.3






23. At least 2 X and one Y - hypogonadism - tall - gynecomastia - low testosterone - high pituitary gonadotropins - infertility -






24. Small round eosinophilic masses found in dieing hepatocytes often containing chromatin remnants seen in viral hepatitis






25. Combination of hyperthyroidism - nodular goiter - absence of exophthalmos






26. Deficient glucose -6- phosphatase - accumulation of glycogen in liver and kidney - hepatomegaly - hypoglycemia






27. Oligohydramnios causes fetus to be smashed






28. Chromosome 19 - allele common in alzheimers






29. Hereditary nephritis associated with nerve deafness and ocular disorders - mutation in gene for the a5 chain of type IV collagen






30. Follicular lymphoma IG heavy chain on 14 - bcl -2 oncogene on 18






31. This comes in a wet variety and a dry one - they are both Vit B1 thiamine deficiency






32. Pigmented iris hamartoma seen in neurofibromatosis






33. Similar to Hurler - deficient L iduronosulfate sulfatase - accumulations of heparin sulfate and dermatan sulfate - hepatospenomegaly - micrognathia - retinal degeneration - joint stiffness - mental retardation - cardiac lesions






34. Similar to paget breast - sometimes related to underlying adenoCA of sweat glands






35. Seen in Down synd - small white spots on periphery of iris






36. Seen in CLL - leukemic B- cells that are fragile






37. Seen in urine of patients with multiple myeloma - Ig light chain either k or l






38. Seen in granuloma inguinale - multiple organisms filling large histiocytes






39. Mutation = paroxysmal nocturnal hemoglobinuria






40. Aka angiokeratoma corporis diffusum universal - deficient a::galactosidase A - accumulate ceramide trihexoside - skin lesions angiokeratomas - fever - burning pain in extremities - cardiovascular and cerebrovascular involvement - death as adult by re






41. Paraneoplastic synd looks like myasthenia gravis - often small cell lung CA






42. Hereditary nonpolyposis colon cancer - DNA repair genes messed up






43. Myc :: neuroblastoma amplicatiion correlates inversely with degree of differentiation






44. Polyostotic fibrous dysplasia - precocious puberty - caf






45. Modest elevated serum unconj bilirubin - due to decreased uptake by liver cells and reduced activity of glucuronyl transferase






46. Hemihypertrophy - macroglossia - organomegaly - neonatal hypoglycemia - various embryonal tumors - deleted WT 2 gene






47. Malabsorption syndrome - Tropheryma wippelii bacilli - small intestine commonly affected - arthralgias - cardiac - and neuro symptoms






48. Triad of ovarian fibroma - ascites - hydrothorax






49. Area of focal interstitial myocardial inflammation characterized by fragmented collagen and fibrinoid material - by large cells (Anitschkow myocytes) and occasional multinucleated giant cells (Aschoff cells)






50. Paternal transmission del (15)(q11q13) - hypogonad - hypotonia - mental retardation - behavior probs - uncrontrolled appetite