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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Seen in Down synd - small white spots on periphery of iris






2. Seen in granuloma inguinale - multiple organisms filling large histiocytes






3. Renal tubular dysfunction - impaired reabsorption of glucose - amino acids - phosphate - and bicarb thus glycosuria - hyperphosphaturia - hypophosphatemia - aminoaciduria - systemic acidosis






4. Appears as multiple wart - like lesions resembling condyloma accuminatum






5. Aka IgA nephropathy - deposition of IgA in mesangium - benign recurrent hematuria in kids following infection






6. Materal transmission del(15)(q11q13) - aka happy puppet syndrome - mental retardation - ataxia - seizures - inappropriate laughter






7. Hamartomatous polyps in colon and small intest - freckles on lips - hands - genitalia - higher incidence of adeno CA of colon and other malignancies - stomach - breast - ovaries






8. Defective cilia - sinusitis - bronchiectasis - situs inversus - sometimes hearing loss and male sterility






9. Hereditary nephritis associated with nerve deafness and ocular disorders - mutation in gene for the a5 chain of type IV collagen






10. Malabsorption syndrome - Tropheryma wippelii bacilli - small intestine commonly affected - arthralgias - cardiac - and neuro symptoms






11. Autosomal dominant - numerous adenomatous polyps along with osteomas and soft tissue tumors






12. Tumor suppressor common in familial polyposis coli and adenoCA of colon as well as other tumors






13. Tumor suppressor mutated in wilms tumor






14. Follicular lymphoma IG heavy chain on 14 - bcl -2 oncogene on 18






15. Tumor suppressor mutated in breast and ovary






16. Gene product facilitates apoptosis






17. Small round blue cell tumor of bone - long bones - kids - 11:22 transloc






18. X linked - aka immunodeficiency with thrombocytopenia and eczema - total immunoglobulins often normal - recurrent infections






19. Tumor suppressor mutated in Von Recklinhousen






20. Asbestosis - yellow - brown - rod shaped body with clubbed ends - stain with Prussian blue






21. Deficient glucocerebrosidase - accumulation of glucocerebroside in cells of mononuclear phagocyte system 3 types ::






22. Aka trisomy 18 - mental retardation - prominent occiput - micrognathia (small jaw) - low::set ears - rocker::bottom feet - finger deformities - congenital heart dx






23. Associated with 90% cases of ankylosing spondylitis - common in rheumatoid arthritis






24. Development of large pituitary adenomas following bilat adrenalectomy






25. Aka allergic granulomatous angiitis - necrotizing vasculitis - variant of polyarteritis nodosa - involves pulmonary vasculature - peripheral eosinophilia - and asthma






26. Mutation here causes pseudohypoparathyroidism






27. Paraneoplastic synd looks like myasthenia gravis - often small cell lung CA






28. Port wine stain on face - ipsilateral glaucoma - vascular lesions of ocular choroidal tissue - extensive hemangiomatous involvement of meninges






29. Adenomatous polyps with tumors of CNS






30. 5p chromosome deletion - severe mental retardation - microcephaly - catlike cry - low birth weight - round face - hypertelorism (wide eyes)






31. Single erythematous plaque on shaft of penis or scrotum






32. Chromosome 19 - allele common in alzheimers






33. Thyroid replacement by fibrous tissue - unkown origin - mimics






34. Ovarian tumor resembling bladder transitional epith






35. Gene product inhibits apoptosis






36. Iron deficient anemia associated with upper::esophageal web






37. Osteophytes at PIP joints






38. Aka thromboangiitis obliterans - acute inflame of small and med arteries of extremities - extending to adjacent veins and nerves - young jewish men - painful ischemic dx - worse with smoking






39. Mucopolysaccharidosis - deficient a L iduronidase - accumulations of heparin sulfate and dermatan sulfate in heart - brain - liver - and other organs - progressive - hepatosplenomagaly - dwarfism - gargoyle - like facies - stubby fingers - corneal cl






40. Thrombotic occlusion of major hepatic veins - abnormal pain - jaundice - hepatomegaly - acites - liver failure - assoc with polycythemia vera - hepatocellular CA - and other common neoplasms - may occur as a complication of pregnancy






41. Acute inflammatory demyelinating dx primarily involving peripheral nerves






42. B1 thiamine - B2 riboflavin - B3 niacin - B6 pyridoxine - B12 cobalamin - C ascorbic acid - D calciferol - E a::tocopherol






43. B Thalassemia major






44. Pigmented iris hamartoma seen in neurofibromatosis






45. Paracentric inversion or translocation with 17 associated with papillary thyroid CA






46. Unknown etiology - necrotizing granulomatous vasculitis of small to medium sized vessels of the respiratory tract - kidneys - and other organs - circulating C- ANCAs






47. Aspirin toxicity seen in kids after acute febrile viral dx - microvesicular fatty change in liver and encephalopathy






48. Diffuse nodular diabetic glomerulosclerosis






49. Associated with breast alone (isn't one of these associated with prostate? Check)






50. Seen in insulinoma - episodic hyperinsulinemia and hypoglycemia - CNS dysfunction - reversal of CNS probs with administration of glucose