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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Aneurysm at small artery bifurcations






2. Paraneoplastic synd looks like myasthenia gravis - often small cell lung CA






3. Epithelial cells with eosinophilc granular cytoplasm seen in hashimoto






4. Eosinophilic intracytoplasmic inclusions in hippocampus and purkinje cells seen in rabies infection






5. Autosomal dominant - numerous adenomatous polyps along with osteomas and soft tissue tumors






6. Aka thromboangiitis obliterans - acute inflame of small and med arteries of extremities - extending to adjacent veins and nerves - young jewish men - painful ischemic dx - worse with smoking






7. Seen in granuloma inguinale - multiple organisms filling large histiocytes






8. Clear cell renal tumor seen in kids






9. Tumor suppressor mutated in breast and ovary






10. Mucopolysaccharidosis - deficient a L iduronidase - accumulations of heparin sulfate and dermatan sulfate in heart - brain - liver - and other organs - progressive - hepatosplenomagaly - dwarfism - gargoyle - like facies - stubby fingers - corneal cl






11. Aka mucocutaneous lymph node syndrome - acute self - limited - infants and young kids - acute necrotizing vasculitis of small and medium vessels - fever hemorrhagic edema of conjunctivae - lips and oral mucosa - and cervical LAD - can cause coronary






12. Aka osteitis deformans - increased osteoclastic and osteoblastic activity






13. Seen in hyperacute rejection - = acute inflammation - fibrinoid necrosis of small vessels - and extensive thrombosis






14. Autosomal recessive - unusually large platelets - lack of 'GPIb IX V'






15. Associated with papillary thyroid CA






16. Thyroid replacement by fibrous tissue - unkown origin - mimics






17. Mesangial matrix material acculmulations seen in nodular glomerulosclerosis seen in diabetic nephropathy






18. Primary aldosteronism






19. Deficient fibrillin (constituent of microfibrils) - arachnodactyly - ectopia lentis - aortic aneurysm - mitral valve prolapsed






20. Autosomal recessive - neutropenia - albinism - cranial and peripheral neuropathy - tendency to develop repeated infections - abnormal WBCs (abnormal mictotubul formation and large cytoplasmic granules = lysosomes)






21. Gene mutated in achondroplasia (most common form of dwarfism) - located at 4p16.3






22. Urethritis - conjunctivitis - arthritis - associated with venereal or intestinal infection






23. Thrombotic occlusion of major hepatic veins - abnormal pain - jaundice - hepatomegaly - acites - liver failure - assoc with polycythemia vera - hepatocellular CA - and other common neoplasms - may occur as a complication of pregnancy






24. Modest elevated serum unconj bilirubin - due to decreased uptake by liver cells and reduced activity of glucuronyl transferase






25. Autoimmune hypothyroid - hurthle cells common






26. Tumor suppressor mutated in wilms tumor






27. Associated with 90% cases of ankylosing spondylitis - common in rheumatoid arthritis






28. This comes in a wet variety and a dry one - they are both Vit B1 thiamine deficiency






29. Appears as multiple wart - like lesions resembling condyloma accuminatum






30. Deficient sphingomyelinase - accumulation of sphingomyelin in phagocytes - foamy histiocytes in liver - spleen - lymph nodes - skin - hepatosplenomegaly - anemia fever - occasional neuro degeneration - half have cherry red spot macula






31. Pituitary insufficiency post - partum - low TSH ACTH






32. Parkinsonism with autonomic dysfunction and orthostatic hypotension






33. Aka lentigo maligna - precursor to lentigo maligna melanoma






34. Intracytoplasmic inclusions seen in leydig cell tumors p283






35. Oncogenes that code for p21 proteins which are membrane signalers






36. Thiamine deficiency - cerebral dysfunction - aka alcoholic encephalopathy - hemorrhagic lesions in the mamillary bodies - confusion - ataxia - ophthalmoplegia - and memory loss plus confabulation p 105 and p115






37. Seen in papillary thyroid CA






38. Protooncogene mutated in medulary thyroid CA (MENII)






39. Aka polycystic ovary syndrome - young women - amenorrhea - infertility - obesity - hirsutism






40. Manifestation of lymphplasmocytic lymphoma - B cell neoplasm






41. B Thalassemia major






42. Philadelphia chromosome - CML bcr abl fusion c - abl on 9 - bcr on 22






43. Osteophytes at PIP joints






44. Hemangioblastoma or cavernous hemangioma of cerebellum - brainstem or retina - adenomas - cysts in liver - kidney - pancreas - and other organs - increased renal cell CA - gene = short arm of chromosome 3






45. Catastrophic adrenal insuff and vascular collapse - hemorrhagic necrosis of adrenal cortex






46. Small round blue cell tumor of bone - long bones - kids - 11:22 transloc






47. Small round eosinophilic masses found in dieing hepatocytes often containing chromatin remnants seen in viral hepatitis






48. Deficient hexosaminidase A - GM2 ganglioside accumulation - especially in neurons - CNS degeneration - mental/motor deterioration - blindness - cherry red spot on macula - death by 4 years of age






49. Metastatic stomach CA to ovary






50. Variant of rheumatoid arthritis - splenmegally - neutropenia - RA