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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Aka hereditary hemorrhagic telangectasia - telangectasias in skin and mucous membranes - epistaxis - GI bleeds






2. Hemangioblastoma or cavernous hemangioma of cerebellum - brainstem or retina - adenomas - cysts in liver - kidney - pancreas - and other organs - increased renal cell CA - gene = short arm of chromosome 3






3. Pituitary insufficiency post - partum - low TSH ACTH






4. Triad of ovarian fibroma - ascites - hydrothorax






5. Protooncogene mutated in medulary thyroid CA (MENII)






6. Acute inflammatory demyelinating dx primarily involving peripheral nerves






7. Deficient glucocerebrosidase - accumulation of glucocerebroside in cells of mononuclear phagocyte system 3 types ::






8. Eczematoid lesion of nipple areola - large cells with clear 'halo like' area - invade epidermis - underlying ductal CA






9. Seen in CLL - leukemic B- cells that are fragile






10. Gene product inhibits apoptosis






11. Paracentric inversion or translocation with 17 associated with papillary thyroid CA






12. Seen in hyperacute rejection - = acute inflammation - fibrinoid necrosis of small vessels - and extensive thrombosis






13. Autosomal recessive - conj hyperbilirubinemia - defect in bili transport - black color to liver






14. Seen in insulinoma - episodic hyperinsulinemia and hypoglycemia - CNS dysfunction - reversal of CNS probs with administration of glucose






15. = MEN1






16. Nystagmus - intention tremor - scanning speech - seen in MS






17. DsDNA antibodies and Sm Smith antigen = highly specific for SLE






18. Non::neoplastic tumor like masses - fibrous replacement of resorbed bone






19. Defective in x- linked brutons agammaglobulinemia - B- cell tyrosine kinase






20. Transloc seen in ewing sarcoma






21. Seen in papillary thyroid CA






22. Oncogenes that code for p21 proteins which are membrane signalers






23. Aka osteitis deformans - increased osteoclastic and osteoblastic activity






24. Autoimmune hypothyroid - hurthle cells common






25. Tumor suppressor mutated in wilms tumor






26. Associated with 90% cases of ankylosing spondylitis - common in rheumatoid arthritis






27. = MEN2a






28. At least 2 X and one Y - hypogonadism - tall - gynecomastia - low testosterone - high pituitary gonadotropins - infertility -






29. Minute neutrophilic abscesses found within parakeratotic stratum corneum in psoriasis






30. Subcutaneous fibrosis of dorsum of penis






31. Malabsorption syndrome - Tropheryma wippelii bacilli - small intestine commonly affected - arthralgias - cardiac - and neuro symptoms






32. Infectious disorder - caused postencephalitic parkinsonism






33. Aka chronic progressive histiocytosis - not as bad as Letterer Siwe






34. Peripheral neuropathy - atrophy of muscles - wet - high output cardiac failure - DCM - AV shunting - hypervolemia






35. Urethritis - conjunctivitis - arthritis - associated with venereal or intestinal infection






36. Located on xsome 6 - mutation here = hereditary hemochromatosis






37. Aka angiokeratoma corporis diffusum universal - deficient a::galactosidase A - accumulate ceramide trihexoside - skin lesions angiokeratomas - fever - burning pain in extremities - cardiovascular and cerebrovascular involvement - death as adult by re






38. 2/neu :: oncogene (aka c - erbB2) - in breast cancer = poor prognosis






39. Also seen in urine of MM - stacks of RBCs - will have high ESR






40. Similar to paget breast - sometimes related to underlying adenoCA of sweat glands






41. Oligohydramnios causes fetus to be smashed






42. Seen in Down synd - small white spots on periphery of iris






43. X linked - absence of plasma cells and serum immunoglobulins - cell mediated immunity still ok - no germinal centers - recurrent bacterial infections - resistances to fungal and viral still - btk gene defect






44. Mesangial matrix material acculmulations seen in nodular glomerulosclerosis seen in diabetic nephropathy






45. Aka osteopetrosis - marble bone dx - dense skeleton - failure of osteoclastic activity






46. Deficient a1 -4 glucosidase - accumulation of glycogen in liver - heart - skeletal muscle - cardiomegaly - muscle hypotonia - spelnomegaly - intractable hypoglycemia - death from cardiorespiratory failure before age 3






47. Myc :: neuroblastoma amplicatiion correlates inversely with degree of differentiation






48. Deficient debranching enzyme amylo -1 -6- glucosidase - glycogen in liver - heart - skeletal muscle - stunted growth - hepatomegaly - hypoglycemia






49. Mutation here causes pseudohypoparathyroidism






50. Aka acute disseminated langerhans cell histiocytosis - aggressive - usually fatal - kids hepatosplenomegaly - LAD - pancytopenia - pulmonary involvement - recurrent infections