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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Seen in papillary thyroid CA






2. Osteophytes at DIP joints






3. Aka acute disseminated langerhans cell histiocytosis - aggressive - usually fatal - kids hepatosplenomegaly - LAD - pancytopenia - pulmonary involvement - recurrent infections






4. Autosomal recessive - conj hyperbilirubinemia - defect in bili transport - black color to liver






5. Autoimmune hypothyroid - hurthle cells common






6. Autosomal recessive - unusually large platelets - lack of 'GPIb IX V'






7. Aka lentigo maligna - precursor to lentigo maligna melanoma






8. 5p chromosome deletion - severe mental retardation - microcephaly - catlike cry - low birth weight - round face - hypertelorism (wide eyes)






9. Protooncogene mutated in medulary thyroid CA (MENII)






10. Materal transmission del(15)(q11q13) - aka happy puppet syndrome - mental retardation - ataxia - seizures - inappropriate laughter






11. Paternal transmission del (15)(q11q13) - hypogonad - hypotonia - mental retardation - behavior probs - uncrontrolled appetite






12. Different in that it is the primary disorder - recurrent vasospasm of small arteries and venules - pallor - cyanosis - fingers and toes - young healthy women






13. Acute promyelocytic leukemia PML gene on 15 and RARa on 17






14. Located on xsome 6 - mutation here = hereditary hemochromatosis






15. Deficient muscle phosphorylase - glycogen in skeletal muscle - cramps with exertion






16. Tumor suppressor mutated in breast and ovary






17. Aka hereditary hemorrhagic telangectasia - telangectasias in skin and mucous membranes - epistaxis - GI bleeds






18. Oncogenes that code for p21 proteins which are membrane signalers






19. Variant of rheumatoid arthritis - aka juvenile rheumatoid arthritis






20. Primary adrenal failure






21. Occurs in SLE - small vegitations on either or both surfaces of valves






22. Infectious disorder - caused postencephalitic parkinsonism






23. Ring of copper deposited around iris seen in Wilson






24. Autosomal recessive - neutropenia - albinism - cranial and peripheral neuropathy - tendency to develop repeated infections - abnormal WBCs (abnormal mictotubul formation and large cytoplasmic granules = lysosomes)






25. X linked - aka immunodeficiency with thrombocytopenia and eczema - total immunoglobulins often normal - recurrent infections






26. Hemangioblastoma or cavernous hemangioma of cerebellum - brainstem or retina - adenomas - cysts in liver - kidney - pancreas - and other organs - increased renal cell CA - gene = short arm of chromosome 3






27. Minute neutrophilic abscesses found within parakeratotic stratum corneum in psoriasis






28. Chromosome 19 - allele common in alzheimers






29. Impaired tubular reabsorption of tryptophan - pellagra::like manifestations






30. Combination of hyperthyroidism - nodular goiter - absence of exophthalmos






31. Ovarian tumor resembling bladder transitional epith






32. Binucleated or multinucleated giant cell seen in Hodgkin dx






33. Deficient a1 -4 glucosidase - accumulation of glycogen in liver - heart - skeletal muscle - cardiomegaly - muscle hypotonia - spelnomegaly - intractable hypoglycemia - death from cardiorespiratory failure before age 3






34. Philadelphia chromosome - CML bcr abl fusion c - abl on 9 - bcr on 22






35. Sphingomyelin containing phagocytes seen in Niemman::Pick dx in liver - spleen - lymph nodes and skin






36. Gene product facilitates apoptosis






37. Aka allergic granulomatous angiitis - necrotizing vasculitis - variant of polyarteritis nodosa - involves pulmonary vasculature - peripheral eosinophilia - and asthma






38. Aspirin toxicity seen in kids after acute febrile viral dx - microvesicular fatty change in liver and encephalopathy






39. Deficient hypoxanthine::guanine phosphoribosyltransferase (HGPRT) - low purine metabolism - high uric acid - thus gout - mental retardation - choreoathetosis - spasticity - self mutilation - aggressiveness






40. Oligohydramnios causes fetus to be smashed






41. Aka osteitis deformans - increased osteoclastic and osteoblastic activity






42. Port wine stain on face - ipsilateral glaucoma - vascular lesions of ocular choroidal tissue - extensive hemangiomatous involvement of meninges






43. Defective in x- linked brutons agammaglobulinemia - B- cell tyrosine kinase






44. Similar to paget breast - sometimes related to underlying adenoCA of sweat glands






45. Mesangial matrix material acculmulations seen in nodular glomerulosclerosis seen in diabetic nephropathy






46. Eczematoid lesion of nipple areola - large cells with clear 'halo like' area - invade epidermis - underlying ductal CA






47. Downward displacement of cerebellar tonsils and medulla through foramen magnum






48. Non::neoplastic tumor like masses - fibrous replacement of resorbed bone






49. = MEN2a






50. Mucopolysaccharidosis - deficient a L iduronidase - accumulations of heparin sulfate and dermatan sulfate in heart - brain - liver - and other organs - progressive - hepatosplenomagaly - dwarfism - gargoyle - like facies - stubby fingers - corneal cl