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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. B1 thiamine - B2 riboflavin - B3 niacin - B6 pyridoxine - B12 cobalamin - C ascorbic acid - D calciferol - E a::tocopherol






2. Gene product facilitates apoptosis






3. Associated with Wegener granulomatosis






4. Aka trisomy 18 - mental retardation - prominent occiput - micrognathia (small jaw) - low::set ears - rocker::bottom feet - finger deformities - congenital heart dx






5. Intracytoplasmic proximal dentritic eosinophilic inclusions consisting of actin seen in Alzheimers






6. Single erythematous plaque on shaft of penis or scrotum






7. Autosomal recessive - hepatitis - accumulation of copper due to transport problem - low ceruloplasmin seen - kayser fleischer rings in eyes






8. Impaired tubular reabsorption of tryptophan - pellagra::like manifestations






9. Seen in papillary thyroid CA






10. Epithelial cells with eosinophilc granular cytoplasm seen in hashimoto






11. Mesangial matrix material acculmulations seen in nodular glomerulosclerosis seen in diabetic nephropathy






12. Polyostotic fibrous dysplasia - precocious puberty - caf






13. Aka superior sulcus tumor - seen in bronchogenic CA - often with Horner's






14. Non::neoplastic tumor like masses - fibrous replacement of resorbed bone






15. B Thalassemia major






16. Tumor suppressor mutated in Von Recklinhousen






17. Aka velocardiofacial syndrome and CATCH 22 syndrome - micro deletion of 22q11 - Cardiac abnormalities - Abnormal facies - T cell deficit due to thymic hypoplasia - Cleft palate - Hypocalcemia due to hypoparathyroidism - from poor development of 3rd a






18. Aka subcortical leukoencephalopathy - assoc with HTN - multiple lacunar infarcts and progressive demyelination in subcortical area






19. Also seen in urine of MM - stacks of RBCs - will have high ESR






20. Deficient sphingomyelinase - accumulation of sphingomyelin in phagocytes - foamy histiocytes in liver - spleen - lymph nodes - skin - hepatosplenomegaly - anemia fever - occasional neuro degeneration - half have cherry red spot macula






21. Aspirin toxicity seen in kids after acute febrile viral dx - microvesicular fatty change in liver and encephalopathy






22. Downward displacement of cerebellar tonsils and medulla through foramen magnum






23. Aka thromboangiitis obliterans - acute inflame of small and med arteries of extremities - extending to adjacent veins and nerves - young jewish men - painful ischemic dx - worse with smoking






24. 45 XO - female hypogonadism - hypothyroid - short - webbed neck - 1* amenorrhea p52






25. Hemangioblastoma or cavernous hemangioma of cerebellum - brainstem or retina - adenomas - cysts in liver - kidney - pancreas - and other organs - increased renal cell CA - gene = short arm of chromosome 3






26. Development of large pituitary adenomas following bilat adrenalectomy






27. Pituitary insufficiency post - partum - low TSH ACTH






28. Intracytoplasmic inclusions seen in leydig cell tumors p283






29. 5p chromosome deletion - severe mental retardation - microcephaly - catlike cry - low birth weight - round face - hypertelorism (wide eyes)






30. At least 2 X and one Y - hypogonadism - tall - gynecomastia - low testosterone - high pituitary gonadotropins - infertility -






31. Pigmented iris hamartoma seen in neurofibromatosis






32. Aka allergic granulomatous angiitis - necrotizing vasculitis - variant of polyarteritis nodosa - involves pulmonary vasculature - peripheral eosinophilia - and asthma






33. Hereditary nonpolyposis colon cancer - DNA repair genes messed up






34. Autosomal dominant - numerous adenomatous polyps along with osteomas and soft tissue tumors






35. Osteophytes at DIP joints






36. Osteophytes at PIP joints






37. Thrombotic occlusion of major hepatic veins - abnormal pain - jaundice - hepatomegaly - acites - liver failure - assoc with polycythemia vera - hepatocellular CA - and other common neoplasms - may occur as a complication of pregnancy






38. Aka congenital megacolon - dilation of colon due to absence of ganglion cells






39. Paternal transmission del (15)(q11q13) - hypogonad - hypotonia - mental retardation - behavior probs - uncrontrolled appetite






40. Occurs in SLE - small vegitations on either or both surfaces of valves






41. Similar to Hurler - deficient L iduronosulfate sulfatase - accumulations of heparin sulfate and dermatan sulfate - hepatospenomegaly - micrognathia - retinal degeneration - joint stiffness - mental retardation - cardiac lesions






42. Thyroid replacement by fibrous tissue - unkown origin - mimics






43. Myc :: neuroblastoma amplicatiion correlates inversely with degree of differentiation






44. Area of focal interstitial myocardial inflammation characterized by fragmented collagen and fibrinoid material - by large cells (Anitschkow myocytes) and occasional multinucleated giant cells (Aschoff cells)






45. Aka infantile progressive spinal muscular atrophy - autosomal recessive - LMN disease - infants






46. Variant of rheumatoid arthritis - aka juvenile rheumatoid arthritis






47. Minute neutrophilic abscesses found within parakeratotic stratum corneum in psoriasis






48. Aggressive B- cell lymphoma - EBV - starry sky appearance - c myc






49. Gene product inhibits apoptosis






50. Defective in x- linked brutons agammaglobulinemia - B- cell tyrosine kinase