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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Aspirin toxicity seen in kids after acute febrile viral dx - microvesicular fatty change in liver and encephalopathy






2. Deficient debranching enzyme amylo -1 -6- glucosidase - glycogen in liver - heart - skeletal muscle - stunted growth - hepatomegaly - hypoglycemia






3. Development of large pituitary adenomas following bilat adrenalectomy






4. Port wine stain on face - ipsilateral glaucoma - vascular lesions of ocular choroidal tissue - extensive hemangiomatous involvement of meninges






5. Small follicles filled with eosinophilic secretion - diagnostic feature of granulose cell tumor






6. Paracentric inversion or translocation with 17 associated with papillary thyroid CA






7. Abnormal WT 1 gene - intersexual disorders - nephropathy - wilms tumor






8. Deficient hypoxanthine::guanine phosphoribosyltransferase (HGPRT) - low purine metabolism - high uric acid - thus gout - mental retardation - choreoathetosis - spasticity - self mutilation - aggressiveness






9. Nuclei arranged in horseshoe - shaped pattern about periphery of cell - characteristic of but not specific for granulomatous TB (as opposed to a foreign body giant cell that has scattered nuclei)






10. Mucinous cell - characteristic of stomach CA met to ovary (krukenberg tumor)






11. Adenomatous polyps with tumors of CNS






12. Materal transmission del(15)(q11q13) - aka happy puppet syndrome - mental retardation - ataxia - seizures - inappropriate laughter






13. Iron deficient anemia associated with upper::esophageal web






14. Eczematoid lesion of nipple areola - large cells with clear 'halo like' area - invade epidermis - underlying ductal CA






15. Binucleated or multinucleated giant cell seen in Hodgkin dx






16. At least 2 X and one Y - hypogonadism - tall - gynecomastia - low testosterone - high pituitary gonadotropins - infertility -






17. Aka angiokeratoma corporis diffusum universal - deficient a::galactosidase A - accumulate ceramide trihexoside - skin lesions angiokeratomas - fever - burning pain in extremities - cardiovascular and cerebrovascular involvement - death as adult by re






18. Modest elevated serum unconj bilirubin - due to decreased uptake by liver cells and reduced activity of glucuronyl transferase






19. Aka thromboangiitis obliterans - acute inflame of small and med arteries of extremities - extending to adjacent veins and nerves - young jewish men - painful ischemic dx - worse with smoking






20. Paraneoplastic synd looks like myasthenia gravis - often small cell lung CA






21. Aka trisomy 18 - mental retardation - prominent occiput - micrognathia (small jaw) - low::set ears - rocker::bottom feet - finger deformities - congenital heart dx






22. Hereditary nonpolyposis colon cancer - DNA repair genes messed up






23. Aka osteopetrosis - marble bone dx - dense skeleton - failure of osteoclastic activity






24. Deficient glucocerebrosidase - accumulation of glucocerebroside in cells of mononuclear phagocyte system 3 types ::






25. Intra::alveolar hemosiderin - laden macrophages caused by RBCs from capillary rupture 2* to pulmonary HTN






26. Variant of rheumatoid arthritis - aka juvenile rheumatoid arthritis






27. Acute inflammatory demyelinating dx primarily involving peripheral nerves






28. Area of focal interstitial myocardial inflammation characterized by fragmented collagen and fibrinoid material - by large cells (Anitschkow myocytes) and occasional multinucleated giant cells (Aschoff cells)






29. Superclavicular lymph node identifying metastatic stomach CA






30. Deficient hexosaminidase A - GM2 ganglioside accumulation - especially in neurons - CNS degeneration - mental/motor deterioration - blindness - cherry red spot on macula - death by 4 years of age






31. Asbestosis - yellow - brown - rod shaped body with clubbed ends - stain with Prussian blue






32. Malignant lymphoma with features resembling inflammatory disorder - young men - Reed Sternburg cells






33. Intracytoplasmic inclusions seen in leydig cell tumors p283






34. Hamartomatous polyps in colon and small intest - freckles on lips - hands - genitalia - higher incidence of adeno CA of colon and other malignancies - stomach - breast - ovaries






35. Aneurysm at small artery bifurcations






36. Acute promyelocytic leukemia PML gene on 15 and RARa on 17






37. Thrombotic occlusion of major hepatic veins - abnormal pain - jaundice - hepatomegaly - acites - liver failure - assoc with polycythemia vera - hepatocellular CA - and other common neoplasms - may occur as a complication of pregnancy






38. Aka chronic progressive histiocytosis - not as bad as Letterer Siwe






39. Autoimmune hypothyroid - hurthle cells common






40. Radiologic appearance of periostium in bone tumors






41. Deficient sphingomyelinase - accumulation of sphingomyelin in phagocytes - foamy histiocytes in liver - spleen - lymph nodes - skin - hepatosplenomegaly - anemia fever - occasional neuro degeneration - half have cherry red spot macula






42. Mutation = paroxysmal nocturnal hemoglobinuria






43. Ovarian tumor resembling bladder transitional epith






44. DsDNA antibodies and Sm Smith antigen = highly specific for SLE






45. Minute neutrophilic abscesses found within parakeratotic stratum corneum in psoriasis






46. Seen in urine of patients with multiple myeloma - Ig light chain either k or l






47. Autosomal recessive - hepatitis - accumulation of copper due to transport problem - low ceruloplasmin seen - kayser fleischer rings in eyes






48. Urethritis - conjunctivitis - arthritis - associated with venereal or intestinal infection






49. Hereditary nephritis associated with nerve deafness and ocular disorders - mutation in gene for the a5 chain of type IV collagen






50. On lymph node biopsy - seen with Burkitt lymphoma