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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Infectious disorder - caused postencephalitic parkinsonism






2. Aneurysm at small artery bifurcations






3. Hereditary nephritis associated with nerve deafness and ocular disorders - mutation in gene for the a5 chain of type IV collagen






4. = MEN2a






5. Occurs in SLE - small vegitations on either or both surfaces of valves






6. Minute neutrophilic abscesses found within parakeratotic stratum corneum in psoriasis






7. Autosomal dominant - fatal - progressive degeneration of striatum and frontal cortex with neuronal depletion and gliosis






8. 2/neu :: oncogene (aka c - erbB2) - in breast cancer = poor prognosis






9. Lots of tumors - breast CA - soft tissue sarc - brain tumors - leukemias - has loss of p53 tumor suppressor gene






10. Seen in CLL - leukemic B- cells that are fragile






11. Small round eosinophilic masses found in dieing hepatocytes often containing chromatin remnants seen in viral hepatitis






12. Seen in Down synd - small white spots on periphery of iris






13. On lymph node biopsy - seen with Burkitt lymphoma






14. Hemangioblastoma or cavernous hemangioma of cerebellum - brainstem or retina - adenomas - cysts in liver - kidney - pancreas - and other organs - increased renal cell CA - gene = short arm of chromosome 3






15. DsDNA antibodies and Sm Smith antigen = highly specific for SLE






16. Deficient hypoxanthine::guanine phosphoribosyltransferase (HGPRT) - low purine metabolism - high uric acid - thus gout - mental retardation - choreoathetosis - spasticity - self mutilation - aggressiveness






17. Eczematoid lesion of nipple areola - large cells with clear 'halo like' area - invade epidermis - underlying ductal CA






18. Renal tubular dysfunction - impaired reabsorption of glucose - amino acids - phosphate - and bicarb thus glycosuria - hyperphosphaturia - hypophosphatemia - aminoaciduria - systemic acidosis






19. Sphingomyelin containing phagocytes seen in Niemman::Pick dx in liver - spleen - lymph nodes and skin






20. Thrombotic occlusion of major hepatic veins - abnormal pain - jaundice - hepatomegaly - acites - liver failure - assoc with polycythemia vera - hepatocellular CA - and other common neoplasms - may occur as a complication of pregnancy






21. Appears as multiple wart - like lesions resembling condyloma accuminatum






22. Binucleated or multinucleated giant cell seen in Hodgkin dx






23. Defective cilia - sinusitis - bronchiectasis - situs inversus - sometimes hearing loss and male sterility






24. At least 2 X and one Y - hypogonadism - tall - gynecomastia - low testosterone - high pituitary gonadotropins - infertility -






25. Retinoblastoma on chromosome 13






26. Aka antiglomerular basement membrane dx - antibodies against alveolar and glomerular basement membranes - linear immunoflorescence






27. Similar to Dubin Johnson with no black liver






28. Scheinker syndrome :: prion dx - fatal familial insomnia






29. Unknown etiology - necrotizing granulomatous vasculitis of small to medium sized vessels of the respiratory tract - kidneys - and other organs - circulating C- ANCAs






30. Clear cell renal tumor seen in kids






31. Acute inflammatory demyelinating dx primarily involving peripheral nerves






32. Tumor suppressor mutated in Von Recklinhousen






33. Deficient sphingomyelinase - accumulation of sphingomyelin in phagocytes - foamy histiocytes in liver - spleen - lymph nodes - skin - hepatosplenomegaly - anemia fever - occasional neuro degeneration - half have cherry red spot macula






34. Oncogenes that code for p21 proteins which are membrane signalers






35. Mesangial matrix material acculmulations seen in nodular glomerulosclerosis seen in diabetic nephropathy






36. Aka thromboangiitis obliterans - acute inflame of small and med arteries of extremities - extending to adjacent veins and nerves - young jewish men - painful ischemic dx - worse with smoking






37. B1 thiamine - B2 riboflavin - B3 niacin - B6 pyridoxine - B12 cobalamin - C ascorbic acid - D calciferol - E a::tocopherol






38. Hemihypertrophy - macroglossia - organomegaly - neonatal hypoglycemia - various embryonal tumors - deleted WT 2 gene






39. Mutation = paroxysmal nocturnal hemoglobinuria






40. Triad of ovarian fibroma - ascites - hydrothorax






41. Pigmented iris hamartoma seen in neurofibromatosis






42. Metastatic stomach CA to ovary






43. Deficient muscle phosphorylase - glycogen in skeletal muscle - cramps with exertion






44. Malabsorption syndrome - Tropheryma wippelii bacilli - small intestine commonly affected - arthralgias - cardiac - and neuro symptoms






45. Aka hereditary hemorrhagic telangectasia - telangectasias in skin and mucous membranes - epistaxis - GI bleeds






46. Severe unconj hyperbilirubinemia due to deficient glucuronyl transferase






47. Downward displacement of cerebellar tonsils and medulla through foramen magnum






48. Similar to paget breast - sometimes related to underlying adenoCA of sweat glands






49. Aka trisomy 13 - mental retardation - microcephaly - micropthalmia - brain abnormalities - cleft lip/palate - polydactyly - rockerbottom feet - congenital heart dx






50. Combination of hyperthyroidism - nodular goiter - absence of exophthalmos