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Test your basic knowledge |
USMLE Brs Pathology Vocab
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Subjects
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health-sciences
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usmle
Instructions:
Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Deficient muscle phosphorylase - glycogen in skeletal muscle - cramps with exertion
Donovan bodies
McArdle syndrome
N
Von economo encephalitis
2. Aka allergic granulomatous angiitis - necrotizing vasculitis - variant of polyarteritis nodosa - involves pulmonary vasculature - peripheral eosinophilia - and asthma
Bowenoid papulosis
Simmonds dx
Churg Strauss syndrome
Arthus reaction
3. Gene product inhibits apoptosis
Reidel thyroiditis
Bcl2
Chromosome 10
Wiskott Aldrich syndrome
4. Tumor suppressor mutated in wilms tumor
WT1 and WT2
Beriberi
McCune Albright syndrome
Edwards syndrome
5. Downward displacement of cerebellar tonsils and medulla through foramen magnum
Gaucher dx
Arnold Chiari formation
Von Hippel Lindau dx
Waterhouse Friderichsen syndrome
6. Hemangioblastoma or cavernous hemangioma of cerebellum - brainstem or retina - adenomas - cysts in liver - kidney - pancreas - and other organs - increased renal cell CA - gene = short arm of chromosome 3
Names of Vitamins
11:22
Von Hippel Lindau dx
Zenker diverticulum
7. Polyostotic fibrous dysplasia - precocious puberty - caf
McCune Albright syndrome
Denys Drash syndrome
Hodgkin dx
Simmonds dx
8. Aka antiglomerular basement membrane dx - antibodies against alveolar and glomerular basement membranes - linear immunoflorescence
Peutz Jeghers syndrome
Reed Sternburg cell
Goodpasture syndrome
Call Exner bodies
9. Dysplastic cell seen in HPV
Von economo encephalitis
Koilocyte
Kayser Fleischer ring
Kimmelstiel Wilson nodules
10. Unknown etiology - necrotizing granulomatous vasculitis of small to medium sized vessels of the respiratory tract - kidneys - and other organs - circulating C- ANCAs
Wermer syndrome
GNAS1
ret
Wegener granulomatosis
11. Port wine stain on face - ipsilateral glaucoma - vascular lesions of ocular choroidal tissue - extensive hemangiomatous involvement of meninges
ANAs in SLE
Paget dx of vulva
Sturge Weber syndrome
Waldenstrom Macroglobulinemia
12. Deficient hypoxanthine::guanine phosphoribosyltransferase (HGPRT) - low purine metabolism - high uric acid - thus gout - mental retardation - choreoathetosis - spasticity - self mutilation - aggressiveness
Wilms tumor
Dubin Johnson syndrome
Lesch Nyhan syndrome
Starry sky appearance
13. Impaired tubular reabsorption of tryptophan - pellagra::like manifestations
Arthus reaction
Hartnup dx
Wilms tumor
Whipple triad
14. Autosomal recessive - neutropenia - albinism - cranial and peripheral neuropathy - tendency to develop repeated infections - abnormal WBCs (abnormal mictotubul formation and large cytoplasmic granules = lysosomes)
Peyronie dx
Reed Sternburg cell
ANAs in SLE
Chediak Higashi syndrome
15. Aka thromboangiitis obliterans - acute inflame of small and med arteries of extremities - extending to adjacent veins and nerves - young jewish men - painful ischemic dx - worse with smoking
Meigs syndrome
Mediterranean anemia or Cooley Anemia
14:18
Buerger dx
16. Mutation here causes pseudohypoparathyroidism
Edwards syndrome
ret PTC
Heart failure cells
GNAS1
17. B Thalassemia major
Dubin Johnson syndrome
Henoch Schonlein Purpura
Mediterranean anemia or Cooley Anemia
Pompe dx
18. Seen in insulinoma - episodic hyperinsulinemia and hypoglycemia - CNS dysfunction - reversal of CNS probs with administration of glucose
Hfe gene
NF1
Whipple triad
McArdle syndrome
19. Small round blue cell tumor of bone - long bones - kids - 11:22 transloc
Ewing sarcoma
Lynch syndrome
DiGeorge syndrome
Bernard Soulier dx
20. Triad of ovarian fibroma - ascites - hydrothorax
Meigs syndrome
Hodgkin dx
Btk gene
Councilman body
21. Autosomal dominant - numerous adenomatous polyps along with osteomas and soft tissue tumors
Lisch nodule
Beckwith Weidemann syndrome
Brown tumor
Gardner syndrome
22. Similar to Hurler - deficient L iduronosulfate sulfatase - accumulations of heparin sulfate and dermatan sulfate - hepatospenomegaly - micrognathia - retinal degeneration - joint stiffness - mental retardation - cardiac lesions
Budd Chiari
Gilbert syndrome
Hunter syndrome
Ras oncogenes
23. Single erythematous plaque on shaft of penis or scrotum
Crigler Najjar syndrome
Bowen dx
APC
Tay Sachs dx
24. Hamartomatous polyps in colon and small intest - freckles on lips - hands - genitalia - higher incidence of adeno CA of colon and other malignancies - stomach - breast - ovaries
Btk gene
Peutz Jeghers syndrome
HER
p53
25. Located on xsome 6 - mutation here = hereditary hemochromatosis
Edwards syndrome
FGFR3
Langhans giant cell
Hfe gene
26. Deficient sphingomyelinase - accumulation of sphingomyelin in phagocytes - foamy histiocytes in liver - spleen - lymph nodes - skin - hepatosplenomegaly - anemia fever - occasional neuro degeneration - half have cherry red spot macula
Niemann Pick dx
Turner syndrome
Bax
DiGeorge syndrome
27. Osteophytes at PIP joints
Bouchard nodes
Hand Schuller Christian dx
Chediak Higashi syndrome
Von economo encephalitis
28. Area of focal interstitial myocardial inflammation characterized by fragmented collagen and fibrinoid material - by large cells (Anitschkow myocytes) and occasional multinucleated giant cells (Aschoff cells)
Henoch Schonlein Purpura
DiGeorge syndrome
Bax
Aschoff body
29. Mesangial matrix material acculmulations seen in nodular glomerulosclerosis seen in diabetic nephropathy
ret
Rb gene
Kimmelstiel Wilson nodules
11:22
30. DsDNA antibodies and Sm Smith antigen = highly specific for SLE
Guillain Barre syndrome
C ANCA
Von Hippel Lindau dx
ANAs in SLE
31. Aka chronic progressive histiocytosis - not as bad as Letterer Siwe
Kimmelstiel Wilson nodules
Hand Schuller Christian dx
Brown tumor
Turner syndrome
32. Chromosome 19 - allele common in alzheimers
Kawasaki dx
Potter sequence
Arnold Chiari formation
E4 allele of apoprotein E
33. Seen in granuloma inguinale - multiple organisms filling large histiocytes
Donovan bodies
Takayasu arteritis
Reye syndrome
Aschoff body
34. Malabsorption syndrome - Tropheryma wippelii bacilli - small intestine commonly affected - arthralgias - cardiac - and neuro symptoms
Whipple dx
Lesch Nyhan syndrome
Brutons Agammaglobulinemia
Angelman syndrome
35. Gene product facilitates apoptosis
Graves dx
Bax
Simmonds dx
E4 allele of apoprotein E
36. Thrombotic occlusion of major hepatic veins - abnormal pain - jaundice - hepatomegaly - acites - liver failure - assoc with polycythemia vera - hepatocellular CA - and other common neoplasms - may occur as a complication of pregnancy
Bowenoid papulosis
Budd Chiari
Rouleaux formation
Potter sequence
37. Autosomal recessive - unusually large platelets - lack of 'GPIb IX V'
Zenker diverticulum
Charcot Bouchard aneurysm
Krukenberg tumor
Bernard Soulier dx
38. X linked - aka immunodeficiency with thrombocytopenia and eczema - total immunoglobulins often normal - recurrent infections
Wiskott Aldrich syndrome
Wilms tumor
Beckwith Weidemann syndrome
Whipple dx
39. Autosomal dominant - fatal - progressive degeneration of striatum and frontal cortex with neuronal depletion and gliosis
11:22
9:22
Huntington dx
Wilson dx
40. Vasosmasm of small vessels - most often in fingers - seen with autoimmune dx like SLE - scleroderma and others (R in CREST) - recurrent vasospasm - always secondary to underlying disorder
Raynaud phenomenon
Alport syndrome
Burkitt lymphoma
Langhans giant cell
41. Adenomatous polyps with tumors of CNS
Whipple triad
Arnold Chiari formation
Plummer Vinson syndrome
Turcot syndrome
42. Severe unconj hyperbilirubinemia due to deficient glucuronyl transferase
Huntington dx
Birbeck granule
Graves dx
Crigler Najjar syndrome
43. Subcutaneous fibrosis of dorsum of penis
Peyronie dx
Wernicke Korsakoff syndrome
ANAs in SLE
Von Recklinhousen dx
44. = MEN1
Sheehan syndrome
McArdle syndrome
Patau syndrome
Wermer syndrome
45. Materal transmission del(15)(q11q13) - aka happy puppet syndrome - mental retardation - ataxia - seizures - inappropriate laughter
Kayser Fleischer ring
Angelman syndrome
9:22
Wegener granulomatosis
46. Burkitts c::myc is on 8 - IG heavy chain is on 14
Hashimoto thyroiditis
Brenner tumor
8:14
Hfe gene
47. Eosinophilic intracytoplasmic inclusions in hippocampus and purkinje cells seen in rabies infection
DiGeorge syndrome
Negri bodies
Bowenoid papulosis
McCune Albright syndrome
48. Thyroid replacement by fibrous tissue - unkown origin - mimics
Stein Leventhal syndrome
Reidel thyroiditis
GNAS1
Reinke crystal
49. Vaginal epithelial cell with stippled appearance due to adherent coccobacilli
Clue cell
Kartagener syndrome
Brutons Agammaglobulinemia
Fanconi syndrome
50. X linked - absence of plasma cells and serum immunoglobulins - cell mediated immunity still ok - no germinal centers - recurrent bacterial infections - resistances to fungal and viral still - btk gene defect
Brutons Agammaglobulinemia
Langhans giant cell
Beckwith Weidemann syndrome
N
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