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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Seen in insulinoma - episodic hyperinsulinemia and hypoglycemia - CNS dysfunction - reversal of CNS probs with administration of glucose






2. Seen in urine of patients with multiple myeloma - Ig light chain either k or l






3. Aka pulseless dx - inflammation and stenosis of medium and large sized arteries - often aortic arch thus aortic arch syndrome






4. Renal tubular dysfunction - impaired reabsorption of glucose - amino acids - phosphate - and bicarb thus glycosuria - hyperphosphaturia - hypophosphatemia - aminoaciduria - systemic acidosis






5. Thyroid replacement by fibrous tissue - unkown origin - mimics






6. Urethritis - conjunctivitis - arthritis - associated with venereal or intestinal infection






7. Aka superior sulcus tumor - seen in bronchogenic CA - often with Horner's






8. Small round blue cell tumor of bone - long bones - kids - 11:22 transloc






9. Gene product facilitates apoptosis - decreases bcl::2 and increases Bax






10. Scheinker syndrome :: prion dx - fatal familial insomnia






11. Metastatic stomach CA to ovary






12. Aka trisomy 13 - mental retardation - microcephaly - micropthalmia - brain abnormalities - cleft lip/palate - polydactyly - rockerbottom feet - congenital heart dx






13. Aka lentigo maligna - precursor to lentigo maligna melanoma






14. Abnormal WT 1 gene - intersexual disorders - nephropathy - wilms tumor






15. Variant of rheumatoid arthritis - aka juvenile rheumatoid arthritis






16. Appears as multiple wart - like lesions resembling condyloma accuminatum






17. Paternal transmission del (15)(q11q13) - hypogonad - hypotonia - mental retardation - behavior probs - uncrontrolled appetite






18. Follicular lymphoma IG heavy chain on 14 - bcl -2 oncogene on 18






19. = MEN2a






20. Osteophytes at PIP joints






21. Subcutaneous fibrosis of dorsum of penis






22. 2/neu :: oncogene (aka c - erbB2) - in breast cancer = poor prognosis






23. Intracytoplasmic inclusions seen in leydig cell tumors p283






24. Retinoblastoma on chromosome 13






25. Protooncogene mutated in medulary thyroid CA (MENII)






26. Clear cell renal tumor seen in kids






27. Esophageal diverticulum just above upper esoph sphincter






28. Autosomal dominant - numerous adenomatous polyps along with osteomas and soft tissue tumors






29. Aka congenital megacolon - dilation of colon due to absence of ganglion cells






30. Similar to Hurler - deficient L iduronosulfate sulfatase - accumulations of heparin sulfate and dermatan sulfate - hepatospenomegaly - micrognathia - retinal degeneration - joint stiffness - mental retardation - cardiac lesions






31. Deficient glucose -6- phosphatase - accumulation of glycogen in liver and kidney - hepatomegaly - hypoglycemia






32. Non::neoplastic tumor like masses - fibrous replacement of resorbed bone






33. Seen in CLL - leukemic B- cells that are fragile






34. Modest elevated serum unconj bilirubin - due to decreased uptake by liver cells and reduced activity of glucuronyl transferase






35. Seen in papillary thyroid CA






36. Ovarian tumor resembling bladder transitional epith






37. Aka chronic progressive histiocytosis - not as bad as Letterer Siwe






38. B1 thiamine - B2 riboflavin - B3 niacin - B6 pyridoxine - B12 cobalamin - C ascorbic acid - D calciferol - E a::tocopherol






39. Intracytoplasmic proximal dentritic eosinophilic inclusions consisting of actin seen in Alzheimers






40. Nuclei arranged in horseshoe - shaped pattern about periphery of cell - characteristic of but not specific for granulomatous TB (as opposed to a foreign body giant cell that has scattered nuclei)






41. = MEN1






42. Small follicles filled with eosinophilic secretion - diagnostic feature of granulose cell tumor






43. Impaired tubular reabsorption of tryptophan - pellagra::like manifestations






44. Iron deficient anemia associated with upper::esophageal web






45. On lymph node biopsy - seen with Burkitt lymphoma






46. Seen in Down synd - small white spots on periphery of iris






47. Deficient a1 -4 glucosidase - accumulation of glycogen in liver - heart - skeletal muscle - cardiomegaly - muscle hypotonia - spelnomegaly - intractable hypoglycemia - death from cardiorespiratory failure before age 3






48. Aka angiokeratoma corporis diffusum universal - deficient a::galactosidase A - accumulate ceramide trihexoside - skin lesions angiokeratomas - fever - burning pain in extremities - cardiovascular and cerebrovascular involvement - death as adult by re






49. Aka trisomy 18 - mental retardation - prominent occiput - micrognathia (small jaw) - low::set ears - rocker::bottom feet - finger deformities - congenital heart dx






50. Acute promyelocytic leukemia PML gene on 15 and RARa on 17