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USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Mutation here causes pseudohypoparathyroidism






2. Intracytoplasmic inclusions seen in leydig cell tumors p283






3. Radiologic appearance of periostium in bone tumors






4. Located on xsome 6 - mutation here = hereditary hemochromatosis






5. Tumor suppressor mutated in wilms tumor






6. Eosinophilic intracytoplasmic inclusions in hippocampus and purkinje cells seen in rabies infection






7. Non::neoplastic tumor like masses - fibrous replacement of resorbed bone






8. Autoimmune thyroiditis - hyperthyroid - exophthalmos - increased in HLA DR3 and HLA B8 pos people






9. Deficient glucose -6- phosphatase - accumulation of glycogen in liver and kidney - hepatomegaly - hypoglycemia






10. Retinoblastoma on chromosome 13






11. Sphingomyelin containing phagocytes seen in Niemman::Pick dx in liver - spleen - lymph nodes and skin






12. Mutation = paroxysmal nocturnal hemoglobinuria






13. Transloc seen in ewing sarcoma






14. X linked - absence of plasma cells and serum immunoglobulins - cell mediated immunity still ok - no germinal centers - recurrent bacterial infections - resistances to fungal and viral still - btk gene defect






15. Paracentric inversion or translocation with 17 associated with papillary thyroid CA






16. Associated with Wegener granulomatosis






17. Seen in granuloma inguinale - multiple organisms filling large histiocytes






18. Chromosome 19 - allele common in alzheimers






19. Primary aldosteronism






20. Thiamine deficiency - cerebral dysfunction - aka alcoholic encephalopathy - hemorrhagic lesions in the mamillary bodies - confusion - ataxia - ophthalmoplegia - and memory loss plus confabulation p 105 and p115






21. Seen in urine of patients with multiple myeloma - Ig light chain either k or l






22. Clear cell renal tumor seen in kids






23. Variant of rheumatoid arthritis - aka juvenile rheumatoid arthritis






24. Autosomal dominant - fatal - progressive degeneration of striatum and frontal cortex with neuronal depletion and gliosis






25. Acute promyelocytic leukemia PML gene on 15 and RARa on 17






26. Epithelial cells with eosinophilc granular cytoplasm seen in hashimoto






27. Protooncogene mutated in medulary thyroid CA (MENII)






28. Scheinker syndrome :: prion dx - fatal familial insomnia






29. Subcutaneous fibrosis of dorsum of penis






30. Deficient a1 -4 glucosidase - accumulation of glycogen in liver - heart - skeletal muscle - cardiomegaly - muscle hypotonia - spelnomegaly - intractable hypoglycemia - death from cardiorespiratory failure before age 3






31. Infectious disorder - caused postencephalitic parkinsonism






32. Aggressive B- cell lymphoma - EBV - starry sky appearance - c myc






33. Materal transmission del(15)(q11q13) - aka happy puppet syndrome - mental retardation - ataxia - seizures - inappropriate laughter






34. Metastatic stomach CA to ovary






35. Autosomal recessive - hepatitis - accumulation of copper due to transport problem - low ceruloplasmin seen - kayser fleischer rings in eyes






36. Aka trisomy 18 - mental retardation - prominent occiput - micrognathia (small jaw) - low::set ears - rocker::bottom feet - finger deformities - congenital heart dx






37. Tumor suppressor mutated in breast and ovary






38. This comes in a wet variety and a dry one - they are both Vit B1 thiamine deficiency






39. Urethritis - conjunctivitis - arthritis - associated with venereal or intestinal infection






40. Follicular lymphoma IG heavy chain on 14 - bcl -2 oncogene on 18






41. Tennis racket shaped cytoplasmic inclusion seen in langerhans cells (so also seen in langerhan cell histiocytosis)






42. Catastrophic adrenal insuff and vascular collapse - hemorrhagic necrosis of adrenal cortex






43. Gene mutated in achondroplasia (most common form of dwarfism) - located at 4p16.3






44. Seen in insulinoma - episodic hyperinsulinemia and hypoglycemia - CNS dysfunction - reversal of CNS probs with administration of glucose






45. Hamartomatous polyps in colon and small intest - freckles on lips - hands - genitalia - higher incidence of adeno CA of colon and other malignancies - stomach - breast - ovaries






46. Tumor suppressor mutated in Von Recklinhousen






47. Aka acute disseminated langerhans cell histiocytosis - aggressive - usually fatal - kids hepatosplenomegaly - LAD - pancytopenia - pulmonary involvement - recurrent infections






48. = MEN2a






49. 5p chromosome deletion - severe mental retardation - microcephaly - catlike cry - low birth weight - round face - hypertelorism (wide eyes)






50. Appears as multiple wart - like lesions resembling condyloma accuminatum