Test your basic knowledge |

USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Autosomal recessive - conj hyperbilirubinemia - defect in bili transport - black color to liver






2. Aka subcortical leukoencephalopathy - assoc with HTN - multiple lacunar infarcts and progressive demyelination in subcortical area






3. Downward displacement of cerebellar tonsils and medulla through foramen magnum






4. Mesangial matrix material acculmulations seen in nodular glomerulosclerosis seen in diabetic nephropathy






5. Transloc seen in ewing sarcoma






6. Mutation = paroxysmal nocturnal hemoglobinuria






7. 5p chromosome deletion - severe mental retardation - microcephaly - catlike cry - low birth weight - round face - hypertelorism (wide eyes)






8. Mutation here causes pseudohypoparathyroidism






9. Deficient muscle phosphorylase - glycogen in skeletal muscle - cramps with exertion






10. Aka pulseless dx - inflammation and stenosis of medium and large sized arteries - often aortic arch thus aortic arch syndrome






11. Deficient glucose -6- phosphatase - accumulation of glycogen in liver and kidney - hepatomegaly - hypoglycemia






12. Nystagmus - intention tremor - scanning speech - seen in MS






13. Associated with breast alone (isn't one of these associated with prostate? Check)






14. Hemangioblastoma or cavernous hemangioma of cerebellum - brainstem or retina - adenomas - cysts in liver - kidney - pancreas - and other organs - increased renal cell CA - gene = short arm of chromosome 3






15. Binucleated or multinucleated giant cell seen in Hodgkin dx






16. Associated with Wegener granulomatosis






17. Aka congenital megacolon - dilation of colon due to absence of ganglion cells






18. Malabsorption syndrome - Tropheryma wippelii bacilli - small intestine commonly affected - arthralgias - cardiac - and neuro symptoms






19. Metastatic stomach CA to ovary






20. Aka velocardiofacial syndrome and CATCH 22 syndrome - micro deletion of 22q11 - Cardiac abnormalities - Abnormal facies - T cell deficit due to thymic hypoplasia - Cleft palate - Hypocalcemia due to hypoparathyroidism - from poor development of 3rd a






21. DsDNA antibodies and Sm Smith antigen = highly specific for SLE






22. Aka polycystic ovary syndrome - young women - amenorrhea - infertility - obesity - hirsutism






23. Clear cell renal tumor seen in kids






24. Aka antiglomerular basement membrane dx - antibodies against alveolar and glomerular basement membranes - linear immunoflorescence






25. Lots of tumors - breast CA - soft tissue sarc - brain tumors - leukemias - has loss of p53 tumor suppressor gene






26. Myc :: neuroblastoma amplicatiion correlates inversely with degree of differentiation






27. Scheinker syndrome :: prion dx - fatal familial insomnia






28. Asbestosis - yellow - brown - rod shaped body with clubbed ends - stain with Prussian blue






29. X linked - aka immunodeficiency with thrombocytopenia and eczema - total immunoglobulins often normal - recurrent infections






30. Single erythematous plaque on shaft of penis or scrotum






31. Similar to Dubin Johnson with no black liver






32. Deficient sphingomyelinase - accumulation of sphingomyelin in phagocytes - foamy histiocytes in liver - spleen - lymph nodes - skin - hepatosplenomegaly - anemia fever - occasional neuro degeneration - half have cherry red spot macula






33. Gene mutated in achondroplasia (most common form of dwarfism) - located at 4p16.3






34. Aspirin toxicity seen in kids after acute febrile viral dx - microvesicular fatty change in liver and encephalopathy






35. Tumor suppressor mutated in Von Recklinhousen






36. Intracytoplasmic proximal dentritic eosinophilic inclusions consisting of actin seen in Alzheimers






37. Eosinophilic intracytoplasmic inclusions in hippocampus and purkinje cells seen in rabies infection






38. Hemihypertrophy - macroglossia - organomegaly - neonatal hypoglycemia - various embryonal tumors - deleted WT 2 gene






39. Aka IgA nephropathy - deposition of IgA in mesangium - benign recurrent hematuria in kids following infection






40. Small round blue cell tumor of bone - long bones - kids - 11:22 transloc






41. Small follicles filled with eosinophilic secretion - diagnostic feature of granulose cell tumor






42. Aneurysm at small artery bifurcations






43. Hamartomatous polyps in colon and small intest - freckles on lips - hands - genitalia - higher incidence of adeno CA of colon and other malignancies - stomach - breast - ovaries






44. Sphingomyelin containing phagocytes seen in Niemman::Pick dx in liver - spleen - lymph nodes and skin






45. Aka superior sulcus tumor - seen in bronchogenic CA - often with Horner's






46. Aka hereditary hemorrhagic telangectasia - telangectasias in skin and mucous membranes - epistaxis - GI bleeds






47. Aka angiokeratoma corporis diffusum universal - deficient a::galactosidase A - accumulate ceramide trihexoside - skin lesions angiokeratomas - fever - burning pain in extremities - cardiovascular and cerebrovascular involvement - death as adult by re






48. Tumor suppressor mutated in wilms tumor






49. Aggressive B- cell lymphoma - EBV - starry sky appearance - c myc






50. Variant of rheumatoid arthritis - splenmegally - neutropenia - RA