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Test your basic knowledge |
USMLE Brs Pathology Vocab
Start Test
Study First
Subjects
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health-sciences
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usmle
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Nuclei arranged in horseshoe - shaped pattern about periphery of cell - characteristic of but not specific for granulomatous TB (as opposed to a foreign body giant cell that has scattered nuclei)
Von Recklinhousen dx
Langhans giant cell
E4 allele of apoprotein E
Budd Chiari
2. Adenomatous polyps with tumors of CNS
Turcot syndrome
Plummer dx
Hartnup dx
Von Recklinhousen dx
3. Gene product facilitates apoptosis
Bax
ret PTC
Virchow node
Gilbert syndrome
4. Small follicles filled with eosinophilic secretion - diagnostic feature of granulose cell tumor
Call Exner bodies
Wegener granulomatosis
Starry sky appearance
Donovan bodies
5. Deficient fibrillin (constituent of microfibrils) - arachnodactyly - ectopia lentis - aortic aneurysm - mitral valve prolapsed
C ANCA
Codman triangle
Krukenberg tumor
Marfan syndrome
6. Nystagmus - intention tremor - scanning speech - seen in MS
Smudge cells
Hartnup dx
Felty syndrome
Charcot triad
7. Aka lentigo maligna - precursor to lentigo maligna melanoma
Hutchinson freckle
Potter sequence
Beriberi
Councilman body
8. Triad of ovarian fibroma - ascites - hydrothorax
Meigs syndrome
Wernicke Korsakoff syndrome
Klinefelter syndrome
Hirschsprung dx
9. Downward displacement of cerebellar tonsils and medulla through foramen magnum
Arnold Chiari formation
HLA B27 antigen
Hurler syndrome
Hfe gene
10. Philadelphia chromosome - CML bcr abl fusion c - abl on 9 - bcr on 22
Clue cell
Starry sky appearance
Btk gene
9:22
11. Subcutaneous fibrosis of dorsum of penis
Peyronie dx
Guillain Barre syndrome
Waldenstrom Macroglobulinemia
Munro abscesses
12. Seen in papillary thyroid CA
Orphan annie nuclei
WT1 and WT2
Koilocyte
Arnold Chiari formation
13. Aggressive B- cell lymphoma - EBV - starry sky appearance - c myc
Rouleaux formation
Burkitt lymphoma
Kimmelstiel Wilson nodules
Chediak Higashi syndrome
14. Autoimmune thyroiditis - hyperthyroid - exophthalmos - increased in HLA DR3 and HLA B8 pos people
Potter sequence
Cri du chat syndrome
Graves dx
Gardner syndrome
15. Aka trisomy 13 - mental retardation - microcephaly - micropthalmia - brain abnormalities - cleft lip/palate - polydactyly - rockerbottom feet - congenital heart dx
Patau syndrome
Hirano bodies
WT1 and WT2
Letterer Siwe dx
16. Minute neutrophilic abscesses found within parakeratotic stratum corneum in psoriasis
Denys Drash syndrome
Wiskott Aldrich syndrome
Burkitt lymphoma
Munro abscesses
17. Mucopolysaccharidosis - deficient a L iduronidase - accumulations of heparin sulfate and dermatan sulfate in heart - brain - liver - and other organs - progressive - hepatosplenomagaly - dwarfism - gargoyle - like facies - stubby fingers - corneal cl
Hurler syndrome
Reidel thyroiditis
Whipple dx
Klinefelter syndrome
18. Small round eosinophilic masses found in dieing hepatocytes often containing chromatin remnants seen in viral hepatitis
Councilman body
Henoch Schonlein Purpura
Potter sequence
Sipple syndrome
19. Chromosome 19 - allele common in alzheimers
Hashimoto thyroiditis
E4 allele of apoprotein E
Call Exner bodies
Charcot triad
20. Impaired tubular reabsorption of tryptophan - pellagra::like manifestations
Hartnup dx
McArdle syndrome
Gilbert syndrome
Kimmelsteil Wilson dx
21. Malabsorption syndrome - Tropheryma wippelii bacilli - small intestine commonly affected - arthralgias - cardiac - and neuro symptoms
Wiskott Aldrich syndrome
Whipple dx
Letterer Siwe dx
N
22. Gene product facilitates apoptosis - decreases bcl::2 and increases Bax
Paget dx of bone
p53
Sturge Weber syndrome
Buerger dx
23. Deficient a1 -4 glucosidase - accumulation of glycogen in liver - heart - skeletal muscle - cardiomegaly - muscle hypotonia - spelnomegaly - intractable hypoglycemia - death from cardiorespiratory failure before age 3
Plummer dx
Wernicke Korsakoff syndrome
Still disease
Pompe dx
24. Osteophytes at PIP joints
Bouchard nodes
Bernard Soulier dx
Wilms tumor
Hand Schuller Christian dx
25. Seen in hyperacute rejection - = acute inflammation - fibrinoid necrosis of small vessels - and extensive thrombosis
Plummer dx
Brenner tumor
Burkitt lymphoma
Arthus reaction
26. Paracentric inversion or translocation with 17 associated with papillary thyroid CA
Kayser Fleischer ring
Hashimoto thyroiditis
Chromosome 10
Clue cell
27. Catastrophic adrenal insuff and vascular collapse - hemorrhagic necrosis of adrenal cortex
Raynaud phenomenon
PIG A
Waterhouse Friderichsen syndrome
ret
28. Appears as multiple wart - like lesions resembling condyloma accuminatum
Angelman syndrome
Bowenoid papulosis
Budd Chiari
N
29. Pigmented iris hamartoma seen in neurofibromatosis
Bax
Budd Chiari
Chromosome 10
Lisch nodule
30. Aka infantile progressive spinal muscular atrophy - autosomal recessive - LMN disease - infants
Werdnig Hoffman syndrome
Birbeck granule
Churg Strauss syndrome
Bernard Soulier dx
31. Gene mutated in achondroplasia (most common form of dwarfism) - located at 4p16.3
Reidel thyroiditis
McCune Albright syndrome
FGFR3
Raynaud disease
32. Eosinophilic intracytoplasmic inclusions in hippocampus and purkinje cells seen in rabies infection
Crigler Najjar syndrome
Felty syndrome
Negri bodies
Angelman syndrome
33. Dysplastic cell seen in HPV
Huntington dx
Koilocyte
Reed Sternburg cell
Reidel thyroiditis
34. Aka antiglomerular basement membrane dx - antibodies against alveolar and glomerular basement membranes - linear immunoflorescence
Plummer Vinson syndrome
Pompe dx
Goodpasture syndrome
Wilson dx
35. Occurs in SLE - small vegitations on either or both surfaces of valves
Gaucher dx
Cori dx
Libman Sacks endocarditis
Clue cell
36. Aka chronic progressive histiocytosis - not as bad as Letterer Siwe
GNAS1
Hand Schuller Christian dx
Wegener granulomatosis
Bernard Soulier dx
37. X linked - aka immunodeficiency with thrombocytopenia and eczema - total immunoglobulins often normal - recurrent infections
Hfe gene
Angelman syndrome
Von Recklinhousen dx
Wiskott Aldrich syndrome
38. Hereditary nonpolyposis colon cancer - DNA repair genes messed up
Gilbert syndrome
Ferruginous body
Lynch syndrome
Mediterranean anemia or Cooley Anemia
39. Autosomal recessive - conj hyperbilirubinemia - defect in bili transport - black color to liver
N
Pancoast tumor
Hurler syndrome
Dubin Johnson syndrome
40. Vasosmasm of small vessels - most often in fingers - seen with autoimmune dx like SLE - scleroderma and others (R in CREST) - recurrent vasospasm - always secondary to underlying disorder
GNAS1
Raynaud phenomenon
Chediak Higashi syndrome
p53
41. Esophageal diverticulum just above upper esoph sphincter
Plummer Vinson syndrome
Zenker diverticulum
Von economo encephalitis
ret
42. Intracytoplasmic inclusions seen in leydig cell tumors p283
Signet ring cell
Reinke crystal
Burkitt lymphoma
Hodgkin dx
43. Seen in insulinoma - episodic hyperinsulinemia and hypoglycemia - CNS dysfunction - reversal of CNS probs with administration of glucose
Arthus reaction
Whipple triad
Gilbert syndrome
Still disease
44. Tumor suppressor common in familial polyposis coli and adenoCA of colon as well as other tumors
APC
Dry beriberi
Waldenstrom Macroglobulinemia
Plummer dx
45. Polyostotic fibrous dysplasia - precocious puberty - caf
Dry beriberi
Paget dx of breast
McCune Albright syndrome
Waldenstrom Macroglobulinemia
46. Aka pituitary cachexia - generalized panhypopituitarism
Bernard Soulier dx
Huntington dx
Simmonds dx
Stein Leventhal syndrome
47. 2/neu :: oncogene (aka c - erbB2) - in breast cancer = poor prognosis
Hartnup dx
HER
Brown tumor
Whipple dx
48. X linked - absence of plasma cells and serum immunoglobulins - cell mediated immunity still ok - no germinal centers - recurrent bacterial infections - resistances to fungal and viral still - btk gene defect
Takayasu arteritis
Brutons Agammaglobulinemia
Bowen dx
Albers SCHonberg dx
49. Paraneoplastic synd looks like myasthenia gravis - often small cell lung CA
Lambert Eaton syndrome
C ANCA
Cri du chat syndrome
Still disease
50. 5p chromosome deletion - severe mental retardation - microcephaly - catlike cry - low birth weight - round face - hypertelorism (wide eyes)
Raynaud phenomenon
Hirano bodies
Beckwith Weidemann syndrome
Cri du chat syndrome