Test your basic knowledge |

USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Associated with Wegener granulomatosis






2. Aka subcortical leukoencephalopathy - assoc with HTN - multiple lacunar infarcts and progressive demyelination in subcortical area






3. Variant of rheumatoid arthritis - aka juvenile rheumatoid arthritis






4. Eczematoid lesion of nipple areola - large cells with clear 'halo like' area - invade epidermis - underlying ductal CA






5. Deficient muscle phosphorylase - glycogen in skeletal muscle - cramps with exertion






6. 5p chromosome deletion - severe mental retardation - microcephaly - catlike cry - low birth weight - round face - hypertelorism (wide eyes)






7. Urethritis - conjunctivitis - arthritis - associated with venereal or intestinal infection






8. Subcutaneous fibrosis of dorsum of penis






9. Located on xsome 6 - mutation here = hereditary hemochromatosis






10. Nuclei arranged in horseshoe - shaped pattern about periphery of cell - characteristic of but not specific for granulomatous TB (as opposed to a foreign body giant cell that has scattered nuclei)






11. Appears as multiple wart - like lesions resembling condyloma accuminatum






12. Ovarian tumor resembling bladder transitional epith






13. Burkitts c::myc is on 8 - IG heavy chain is on 14






14. Aspirin toxicity seen in kids after acute febrile viral dx - microvesicular fatty change in liver and encephalopathy






15. Aka allergic granulomatous angiitis - necrotizing vasculitis - variant of polyarteritis nodosa - involves pulmonary vasculature - peripheral eosinophilia - and asthma






16. Autoimmune hypothyroid - hurthle cells common






17. Peripheral neuropathy - atrophy of muscles - wet - high output cardiac failure - DCM - AV shunting - hypervolemia






18. Aka lentigo maligna - precursor to lentigo maligna melanoma






19. Eosinophilic intracytoplasmic inclusions in hippocampus and purkinje cells seen in rabies infection






20. Paraneoplastic synd looks like myasthenia gravis - often small cell lung CA






21. Autosomal dominant - fatal - progressive degeneration of striatum and frontal cortex with neuronal depletion and gliosis






22. Hemorrhagic urticaria of extensor surgaces of arms - legs - and buttocks - with fever - arthralgias - and GI renal involvement similar to IgA nephropathy - associated with URIs






23. Single erythematous plaque on shaft of penis or scrotum






24. Deficient a1 -4 glucosidase - accumulation of glycogen in liver - heart - skeletal muscle - cardiomegaly - muscle hypotonia - spelnomegaly - intractable hypoglycemia - death from cardiorespiratory failure before age 3






25. Follicular lymphoma IG heavy chain on 14 - bcl -2 oncogene on 18






26. Deficient hypoxanthine::guanine phosphoribosyltransferase (HGPRT) - low purine metabolism - high uric acid - thus gout - mental retardation - choreoathetosis - spasticity - self mutilation - aggressiveness






27. Downward displacement of cerebellar tonsils and medulla through foramen magnum






28. Deficient sphingomyelinase - accumulation of sphingomyelin in phagocytes - foamy histiocytes in liver - spleen - lymph nodes - skin - hepatosplenomegaly - anemia fever - occasional neuro degeneration - half have cherry red spot macula






29. Aka velocardiofacial syndrome and CATCH 22 syndrome - micro deletion of 22q11 - Cardiac abnormalities - Abnormal facies - T cell deficit due to thymic hypoplasia - Cleft palate - Hypocalcemia due to hypoparathyroidism - from poor development of 3rd a






30. Vasosmasm of small vessels - most often in fingers - seen with autoimmune dx like SLE - scleroderma and others (R in CREST) - recurrent vasospasm - always secondary to underlying disorder






31. Thyroid replacement by fibrous tissue - unkown origin - mimics






32. Tumor suppressor common in familial polyposis coli and adenoCA of colon as well as other tumors






33. Tennis racket shaped cytoplasmic inclusion seen in langerhans cells (so also seen in langerhan cell histiocytosis)






34. Scheinker syndrome :: prion dx - fatal familial insomnia






35. Renal tubular dysfunction - impaired reabsorption of glucose - amino acids - phosphate - and bicarb thus glycosuria - hyperphosphaturia - hypophosphatemia - aminoaciduria - systemic acidosis






36. X linked - absence of plasma cells and serum immunoglobulins - cell mediated immunity still ok - no germinal centers - recurrent bacterial infections - resistances to fungal and viral still - btk gene defect






37. Radiologic appearance of periostium in bone tumors






38. Seen in hyperacute rejection - = acute inflammation - fibrinoid necrosis of small vessels - and extensive thrombosis






39. Mucinous cell - characteristic of stomach CA met to ovary (krukenberg tumor)






40. Seen in insulinoma - episodic hyperinsulinemia and hypoglycemia - CNS dysfunction - reversal of CNS probs with administration of glucose






41. Seen in papillary thyroid CA






42. Port wine stain on face - ipsilateral glaucoma - vascular lesions of ocular choroidal tissue - extensive hemangiomatous involvement of meninges






43. Oncogenes that code for p21 proteins which are membrane signalers






44. Ring of copper deposited around iris seen in Wilson






45. Sphingomyelin containing phagocytes seen in Niemman::Pick dx in liver - spleen - lymph nodes and skin






46. Aka mucocutaneous lymph node syndrome - acute self - limited - infants and young kids - acute necrotizing vasculitis of small and medium vessels - fever hemorrhagic edema of conjunctivae - lips and oral mucosa - and cervical LAD - can cause coronary






47. Aka chronic progressive histiocytosis - not as bad as Letterer Siwe






48. Aka hereditary hemorrhagic telangectasia - telangectasias in skin and mucous membranes - epistaxis - GI bleeds






49. Binucleated or multinucleated giant cell seen in Hodgkin dx






50. Similar to Dubin Johnson with no black liver