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Test your basic knowledge |
USMLE Brs Pathology Vocab
Start Test
Study First
Subjects
:
health-sciences
,
usmle
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Impaired tubular reabsorption of tryptophan - pellagra::like manifestations
Sheehan syndrome
Hartnup dx
Rouleaux formation
Graves dx
2. Malabsorption syndrome - Tropheryma wippelii bacilli - small intestine commonly affected - arthralgias - cardiac - and neuro symptoms
Whipple dx
Brutons Agammaglobulinemia
Sturge Weber syndrome
Nelson syndrome
3. Primary adrenal failure
Alport syndrome
Btk gene
Ras oncogenes
Addison disease
4. Thrombotic occlusion of major hepatic veins - abnormal pain - jaundice - hepatomegaly - acites - liver failure - assoc with polycythemia vera - hepatocellular CA - and other common neoplasms - may occur as a complication of pregnancy
Alport syndrome
Budd Chiari
Orphan annie nuclei
14:18
5. Gene product inhibits apoptosis
Stein Leventhal syndrome
Felty syndrome
15:17
Bcl2
6. Malignant lymphoma with features resembling inflammatory disorder - young men - Reed Sternburg cells
Takayasu arteritis
Arthus reaction
GNAS1
Hodgkin dx
7. Oncogenes that code for p21 proteins which are membrane signalers
Ras oncogenes
Arthus reaction
Reinke crystal
Charcot triad
8. Eczematoid lesion of nipple areola - large cells with clear 'halo like' area - invade epidermis - underlying ductal CA
Reinke crystal
Zenker diverticulum
Paget dx of breast
Signet ring cell
9. Manifestation of lymphplasmocytic lymphoma - B cell neoplasm
Reinke crystal
Plummer Vinson syndrome
Waldenstrom Macroglobulinemia
15:17
10. Deficient fibrillin (constituent of microfibrils) - arachnodactyly - ectopia lentis - aortic aneurysm - mitral valve prolapsed
Marfan syndrome
Bowenoid papulosis
Gilbert syndrome
C ANCA
11. Aka pulseless dx - inflammation and stenosis of medium and large sized arteries - often aortic arch thus aortic arch syndrome
Takayasu arteritis
APC
Waterhouse Friderichsen syndrome
Crigler Najjar syndrome
12. Autosomal recessive - unusually large platelets - lack of 'GPIb IX V'
Brutons Agammaglobulinemia
Hutchinson freckle
Bernard Soulier dx
APC
13. Hemangioblastoma or cavernous hemangioma of cerebellum - brainstem or retina - adenomas - cysts in liver - kidney - pancreas - and other organs - increased renal cell CA - gene = short arm of chromosome 3
Hurthle cell
Henoch Schonlein Purpura
Fanconi syndrome
Von Hippel Lindau dx
14. Deficient a1 -4 glucosidase - accumulation of glycogen in liver - heart - skeletal muscle - cardiomegaly - muscle hypotonia - spelnomegaly - intractable hypoglycemia - death from cardiorespiratory failure before age 3
McArdle syndrome
Binswanger dx
Prader willi syndrome
Pompe dx
15. Small follicles filled with eosinophilic secretion - diagnostic feature of granulose cell tumor
Virchow node
Kimmelsteil Wilson dx
Plummer Vinson syndrome
Call Exner bodies
16. Tumor suppressor mutated in Von Recklinhousen
Arthus reaction
Reiter syndrome
NF1
McArdle syndrome
17. Single erythematous plaque on shaft of penis or scrotum
Shy Drager syndrome
Bowen dx
Starry sky appearance
Addison disease
18. Burkitts c::myc is on 8 - IG heavy chain is on 14
8:14
Waldenstrom Macroglobulinemia
Foamy histiocyte
Ras oncogenes
19. Seen in granuloma inguinale - multiple organisms filling large histiocytes
Nelson syndrome
Donovan bodies
Von Hippel Lindau dx
Meigs syndrome
20. Autosomal dominant - numerous adenomatous polyps along with osteomas and soft tissue tumors
Turner syndrome
Beckwith Weidemann syndrome
Gardner syndrome
Peyronie dx
21. Iron deficient anemia associated with upper::esophageal web
Wilson dx
Plummer Vinson syndrome
Foamy histiocyte
Felty syndrome
22. Seen in hyperacute rejection - = acute inflammation - fibrinoid necrosis of small vessels - and extensive thrombosis
Gilbert syndrome
Munro abscesses
Arthus reaction
Pancoast tumor
23. Aka congenital megacolon - dilation of colon due to absence of ganglion cells
Albers SCHonberg dx
Hirschsprung dx
Alport syndrome
Buerger dx
24. Aka antiglomerular basement membrane dx - antibodies against alveolar and glomerular basement membranes - linear immunoflorescence
Takayasu arteritis
Goodpasture syndrome
Hashimoto thyroiditis
Buerger dx
25. Chromosome 19 - allele common in alzheimers
Rouleaux formation
Birbeck granule
E4 allele of apoprotein E
Budd Chiari
26. Deficient sphingomyelinase - accumulation of sphingomyelin in phagocytes - foamy histiocytes in liver - spleen - lymph nodes - skin - hepatosplenomegaly - anemia fever - occasional neuro degeneration - half have cherry red spot macula
DiGeorge syndrome
Niemann Pick dx
Fanconi syndrome
Hartnup dx
27. Autosomal dominant - fatal - progressive degeneration of striatum and frontal cortex with neuronal depletion and gliosis
N
Huntington dx
Btk gene
Reiter syndrome
28. Infectious disorder - caused postencephalitic parkinsonism
Von economo encephalitis
Waterhouse Friderichsen syndrome
BRCA1
Birbeck granule
29. Aka infantile progressive spinal muscular atrophy - autosomal recessive - LMN disease - infants
Raynaud phenomenon
Werdnig Hoffman syndrome
Gerstmann Straussler
Hashimoto thyroiditis
30. Aka osteitis deformans - increased osteoclastic and osteoblastic activity
Call Exner bodies
Bernard Soulier dx
Paget dx of bone
Whipple dx
31. Deficient glucocerebrosidase - accumulation of glucocerebroside in cells of mononuclear phagocyte system 3 types ::
Letterer Siwe dx
Gaucher dx
Reiter syndrome
Crigler Najjar syndrome
32. Similar to paget breast - sometimes related to underlying adenoCA of sweat glands
Codman triangle
ret
Paget dx of vulva
Whipple triad
33. Combination of hyperthyroidism - nodular goiter - absence of exophthalmos
Libman Sacks endocarditis
Plummer dx
Von Hippel Lindau dx
Kawasaki dx
34. Mutation = paroxysmal nocturnal hemoglobinuria
Tay Sachs dx
Conn syndrome
PIG A
Smudge cells
35. Aka hereditary hemorrhagic telangectasia - telangectasias in skin and mucous membranes - epistaxis - GI bleeds
Still disease
Henoch Schonlein Purpura
Rb gene
Osler Weber Rendu syndrome
36. Esophageal diverticulum just above upper esoph sphincter
p53
C ANCA
Simmonds dx
Zenker diverticulum
37. Thiamine deficiency - cerebral dysfunction - aka alcoholic encephalopathy - hemorrhagic lesions in the mamillary bodies - confusion - ataxia - ophthalmoplegia - and memory loss plus confabulation p 105 and p115
Wernicke Korsakoff syndrome
Paget dx of bone
Churg Strauss syndrome
Binswanger dx
38. Hemorrhagic urticaria of extensor surgaces of arms - legs - and buttocks - with fever - arthralgias - and GI renal involvement similar to IgA nephropathy - associated with URIs
Von Gierke dx
Henoch Schonlein Purpura
Chromosome 10
Wilson dx
39. Aka trisomy 13 - mental retardation - microcephaly - micropthalmia - brain abnormalities - cleft lip/palate - polydactyly - rockerbottom feet - congenital heart dx
Hand Schuller Christian dx
Negri bodies
Patau syndrome
Munro abscesses
40. Downward displacement of cerebellar tonsils and medulla through foramen magnum
WT1 and WT2
Hurler syndrome
Arnold Chiari formation
8:14
41. Triad of ovarian fibroma - ascites - hydrothorax
Brown tumor
Klinefelter syndrome
Councilman body
Meigs syndrome
42. Peripheral neuropathy - atrophy of muscles - wet - high output cardiac failure - DCM - AV shunting - hypervolemia
Prader willi syndrome
Fanconi syndrome
Rotor syndrome
Dry beriberi
43. Deficient debranching enzyme amylo -1 -6- glucosidase - glycogen in liver - heart - skeletal muscle - stunted growth - hepatomegaly - hypoglycemia
Cori dx
Turcot syndrome
Burkitt lymphoma
Hartnup dx
44. Primary aldosteronism
Niemann Pick dx
Conn syndrome
Hutchinson freckle
Klinefelter syndrome
45. Superclavicular lymph node identifying metastatic stomach CA
Virchow node
14:18
McArdle syndrome
Paget dx of vulva
46. Aka acute disseminated langerhans cell histiocytosis - aggressive - usually fatal - kids hepatosplenomegaly - LAD - pancytopenia - pulmonary involvement - recurrent infections
Gaucher dx
Letterer Siwe dx
Reye syndrome
Angelman syndrome
47. Mucopolysaccharidosis - deficient a L iduronidase - accumulations of heparin sulfate and dermatan sulfate in heart - brain - liver - and other organs - progressive - hepatosplenomagaly - dwarfism - gargoyle - like facies - stubby fingers - corneal cl
Brown tumor
Hurler syndrome
Pancoast tumor
Beckwith Weidemann syndrome
48. Aka trisomy 18 - mental retardation - prominent occiput - micrognathia (small jaw) - low::set ears - rocker::bottom feet - finger deformities - congenital heart dx
Werdnig Hoffman syndrome
Huntington dx
Hfe gene
Edwards syndrome
49. Follicular lymphoma IG heavy chain on 14 - bcl -2 oncogene on 18
Beriberi
Bcl2
14:18
Smudge cells
50. Aspirin toxicity seen in kids after acute febrile viral dx - microvesicular fatty change in liver and encephalopathy
Reye syndrome
Wiskott Aldrich syndrome
N
Crigler Najjar syndrome