Test your basic knowledge |

USMLE Brs Pathology Vocab

Subjects : health-sciences, usmle
Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. At least 2 X and one Y - hypogonadism - tall - gynecomastia - low testosterone - high pituitary gonadotropins - infertility -






2. Epithelial cells with eosinophilc granular cytoplasm seen in hashimoto






3. Ovarian tumor resembling bladder transitional epith






4. Vaginal epithelial cell with stippled appearance due to adherent coccobacilli






5. Aka thromboangiitis obliterans - acute inflame of small and med arteries of extremities - extending to adjacent veins and nerves - young jewish men - painful ischemic dx - worse with smoking






6. Tennis racket shaped cytoplasmic inclusion seen in langerhans cells (so also seen in langerhan cell histiocytosis)






7. 45 XO - female hypogonadism - hypothyroid - short - webbed neck - 1* amenorrhea p52






8. Small follicles filled with eosinophilic secretion - diagnostic feature of granulose cell tumor






9. Mucinous cell - characteristic of stomach CA met to ovary (krukenberg tumor)






10. Hamartomatous polyps in colon and small intest - freckles on lips - hands - genitalia - higher incidence of adeno CA of colon and other malignancies - stomach - breast - ovaries






11. DsDNA antibodies and Sm Smith antigen = highly specific for SLE






12. Renal tubular dysfunction - impaired reabsorption of glucose - amino acids - phosphate - and bicarb thus glycosuria - hyperphosphaturia - hypophosphatemia - aminoaciduria - systemic acidosis






13. Occurs in SLE - small vegitations on either or both surfaces of valves






14. Nuclei arranged in horseshoe - shaped pattern about periphery of cell - characteristic of but not specific for granulomatous TB (as opposed to a foreign body giant cell that has scattered nuclei)






15. Burkitts c::myc is on 8 - IG heavy chain is on 14






16. Small round eosinophilic masses found in dieing hepatocytes often containing chromatin remnants seen in viral hepatitis






17. Superclavicular lymph node identifying metastatic stomach CA






18. Vasosmasm of small vessels - most often in fingers - seen with autoimmune dx like SLE - scleroderma and others (R in CREST) - recurrent vasospasm - always secondary to underlying disorder






19. Deficient glucose -6- phosphatase - accumulation of glycogen in liver and kidney - hepatomegaly - hypoglycemia






20. Intra::alveolar hemosiderin - laden macrophages caused by RBCs from capillary rupture 2* to pulmonary HTN






21. Paraneoplastic synd looks like myasthenia gravis - often small cell lung CA






22. Paternal transmission del (15)(q11q13) - hypogonad - hypotonia - mental retardation - behavior probs - uncrontrolled appetite






23. Defective cilia - sinusitis - bronchiectasis - situs inversus - sometimes hearing loss and male sterility






24. Autoimmune hypothyroid - hurthle cells common






25. Aspirin toxicity seen in kids after acute febrile viral dx - microvesicular fatty change in liver and encephalopathy






26. Autosomal recessive - unusually large platelets - lack of 'GPIb IX V'






27. Unknown etiology - necrotizing granulomatous vasculitis of small to medium sized vessels of the respiratory tract - kidneys - and other organs - circulating C- ANCAs






28. Aka allergic granulomatous angiitis - necrotizing vasculitis - variant of polyarteritis nodosa - involves pulmonary vasculature - peripheral eosinophilia - and asthma






29. Follicular lymphoma IG heavy chain on 14 - bcl -2 oncogene on 18






30. Aka polycystic ovary syndrome - young women - amenorrhea - infertility - obesity - hirsutism






31. Thyroid replacement by fibrous tissue - unkown origin - mimics






32. Myc :: neuroblastoma amplicatiion correlates inversely with degree of differentiation






33. Pituitary insufficiency post - partum - low TSH ACTH






34. X linked - aka immunodeficiency with thrombocytopenia and eczema - total immunoglobulins often normal - recurrent infections






35. Metastatic stomach CA to ovary






36. Osteophytes at DIP joints






37. Intracytoplasmic proximal dentritic eosinophilic inclusions consisting of actin seen in Alzheimers






38. Modest elevated serum unconj bilirubin - due to decreased uptake by liver cells and reduced activity of glucuronyl transferase






39. Deficient fibrillin (constituent of microfibrils) - arachnodactyly - ectopia lentis - aortic aneurysm - mitral valve prolapsed






40. Also seen in urine of MM - stacks of RBCs - will have high ESR






41. Aka superior sulcus tumor - seen in bronchogenic CA - often with Horner's






42. Gene product facilitates apoptosis






43. Abnormal WT 1 gene - intersexual disorders - nephropathy - wilms tumor






44. Hereditary nonpolyposis colon cancer - DNA repair genes messed up






45. Gene mutated in achondroplasia (most common form of dwarfism) - located at 4p16.3






46. On lymph node biopsy - seen with Burkitt lymphoma






47. Small round blue cell tumor of bone - long bones - kids - 11:22 transloc






48. Malabsorption syndrome - Tropheryma wippelii bacilli - small intestine commonly affected - arthralgias - cardiac - and neuro symptoms






49. Appears as multiple wart - like lesions resembling condyloma accuminatum






50. B Thalassemia major