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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Inhaled anesthetics metabolized by liver enzymes which has a major role in the toxicity of these agents






2. SE of demeclocycline






3. Beta 1 agonists used in acute CHF






4. Concern using lithium






5. NSAID that is used for acute condition - such as pre - op anesthesia and has limited duration (<5 days) of use due to nephrotoxicity






6. Drug that causes gray baby syndrome and aplastic anemia






7. DOC for CMV retinitis






8. TCA used in chronic pain - a hypnotic - and has marked antimuscarinic effects






9. Carbamate with intermediate action - used for+A1170 postoperative and neurogenic ileus and urinary retention






10. Triptan available in parenteral and nasal formulation






11. The most common neurologic abnormality in chronic alcoholics






12. Barbiturates decrease the effectiveness of many other drugs via this pharmacokinetics property






13. Opioid associated with respiratory depression - but is used in high risk patients who may not survive full general anesthetia






14. Major SE of bisphosphonates






15. Opioids used in anesthesia






16. GnRH agonist used for infertility or different types of CA depending on pulsatile or steady usage respectively






17. Organophosphate anthelmintic agent with long DOA






18. Agents having active metabolites - long half lives - and a high incidence of adverse effects






19. Non - steroidal estrogen agonist causes clear cell adenocarcinoma of the vagina in daughters of women who used it during pregnancy






20. Distribution of histamine receptors H1 - H2 - and H3






21. 5HT-3 antagonist used in chemotherapeutic induced emesis






22. Agent having no effect on D2 receptors - blocks D4 - reserved for resistant schizophrenia - and can cause fatal agranulocytosis






23. Drug that causes contraction of the uterus






24. SE of clonidine






25. Extrapyramidal dysfunction is more common with these agents - Which block this subtype of dopamine receptor






26. Period of time of therapy after which GC therapy will need to be tapered






27. Antidepressant associated with seizures and cardiotoxicity






28. CCB are DOC for

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29. This step of metabolism makes a drug more hydrophilic and hence augments elimination






30. Treatment with cancer chemotherapy at high doses every 3-4 weeks - too toxic to be used continuously






31. Prototype antagonist of H1 and H2 receptors






32. Metronidazole SE if given with alcohol






33. Antiprogestin used as potent antagonist of GC receptor






34. Weak opioid agonist - poor analgesic - its overdose can cause severe toxicity including respiratory depression - circulatory collapse - pulmonary edema - and seizures






35. Incidence of hyoglycemia with metformin






36. Toxicity of these agents include bradycardia - AV blockade - exacerbation of acute CHF; signs of hypoglycemia may be masked (tachycardia - tremor - and anxiety)






37. Anti - microbials that cause hemolysis in G6PD- deficient patients






38. NSAID also available as an ophthalmic preparation






39. Antidepressant which is inhibitor of CYP450 enzymes and may be associated with hepatic failure






40. Prostaglandins that cause abortions






41. Block glycoprotein IIb/IIIa involved in platelet cross - linking






42. Commonly abused LA which has cardiovascular toxicity including severe hypertension with cerebral hemorrhage - cardiac arrhythmias - and myocardial infarction






43. Treatment of patients with prior episodes of thrombocytopenia after a cycle of cancer chemotherapy






44. Drugs that can be used for infantile spasms






45. Clinical response that may fluctuate in tx of Parkinson's dx

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46. Opioid antagonist that is given orally in alcohol dependency programs






47. All opioids except this agent (which has a muscarinic blocking action) cause pupillary constriction






48. Products of Phase II conjugation






49. When the rate of drug input equals the rate of drug elimination






50. 5HT-3 antagonist that has been associated with QRS and QTc prolongation and should not be used in patients with heart disease