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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Antipsychotic used in the treatment of psychiatric symptoms in patients with dementia






2. Diuretic used to antagonize aldosterone receptors






3. This is combined with L- dopa - inhibits DOPA decarboxylase (active only peripherally) which allows lower effective doses of L- dopa and allows for fewer SE's (GI distress - postural hypotension - and dyskinesias)






4. Laboratory value required to be monitored for patients on valproic acid

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5. Anti - seizure drugs used also for pain of neuropathic orgin






6. Cephalosporin causes kernicterus in neonates






7. Associated with an increased incidence of cataracts in patients treated for glaucoma






8. Benzodiazepine that is used for anesthesia






9. A hormone whose mechanism of action (MOA) utilizes intracellular receptors






10. Acetaminophen only has






11. Aminoglycosides used with loop diuretics potentiate adverse effect






12. Metronidazole SE if given with alcohol






13. Antidote used for tricyclic antidepressants (TCA)






14. Maximum response achieveable from a drug






15. Names of three bisphosphonates available IV






16. This agent used to treat dry mouth in Sj






17. Time it takes for amount of drug to fall to half of its value; this is a constant in first order kinetics (majority of drugs)






18. Contraindications to use of atropine






19. Well - tolerated and are first - line antidepressants

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20. Generation of antihistamine that has the most CNS effects






21. Thrombolytics are used for






22. SE of niacin






23. Most useful in patients with significant anxiety - phobic features - hypochondriasis - and resistant depression






24. All antidepressants have roughly the same efficacy in treating depression - agents are chosen based on these criterion






25. Vitamin given with calcium to ensure proper absorption






26. Agent used for neurological deficits in megaloblastic anemia






27. Other side effects of Quinidine






28. Causes acne - premature closure of epiphyses - masculinization in females - hepatic dysfunction - MI - and increases in libido and aggression






29. Enzyme that metabolizes acetaldehyde to acetate






30. Cardioselective Beta 1- blockers






31. Toxicity of amphotericin






32. SE of phenytoin






33. Endogenous insulin contains






34. Cystitis - postoperative bladder spasms - or incontinence






35. Almost all local anesthetics have this property and sometimes require the administration of vasoconstrictors (ex. Epinephrine) to prolong activity






36. MOA of thiazide diuretics






37. SE of salicylates






38. Antifungal agent used for inhibition of all gonadal and adrenal steroids






39. Agents used in Tourette's dx






40. Important in synthesis of glucose to glycogen in the liver






41. MOA of thiazolindinediones






42. SE of colchicine






43. Some cell cycle non - specific drugs






44. Route of administration of warfarin






45. Opioid antagonist that is given orally in alcohol dependency programs






46. Some of SSRIs' therapeutic effects beside depression






47. GnRH antagonist with more immediate effects - used for infertility






48. Thioamide less likely to cross placenta - inhibits peripheral conversion of T4 to T3 in high doses - and should be used with extreme caution in pregnancy






49. Occurs when sedative hypnotics are used chronically or at high doses






50. Inhaled anesthetic - less likely to lower blood pressure than other agents - and has the smallest effect on respiration