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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Antidote used for iron salt toxicity






2. THC is active ingredient - SE's include impairment of judgment - and reflexes - decreases in blood pressure and psychomotor performance occur






3. Benzodiazepine that has efficacy against absence seizures and in anxiety states - such as agoraphobia






4. Anti - progesterone used as abortifacient






5. SE of hydroxychloroquine






6. SSRI indicated for premenstrual dysphoric disorder






7. Carbamazepine may cause






8. This diuretic decreases aqueous secretion due to lack of HCO3- ion. Causes drowsiness and paresthesias - alkalinization of the urine may precipitate calcium salts - hypokalemia - acidosis






9. Inhibits conversion of cholesterol to pregnenolone therefore inhibiting corticosteroid synthesis






10. Toxicities include nephrotoxicity and ototoxicity - leading to a severe interaction with aminoglycosides






11. Opioid used in the management of withdrawal states






12. Anti - microbials that cause hemolysis in G6PD- deficient patients






13. Agent that is metabolized to acetaldehyde by alcohol dehydrogenase and microsomal ethanol - oxidizing system (MEOS)






14. Antiarrhythmic that exhibits Class II and III properties






15. Drugs of choice for status epilepticus






16. These agents are congeners of Amphetamine

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17. Metronidazole SE if given with alcohol






18. Used for Addison's disease - Congenital Adrenal Hyperplasia (CAH) - inflammation - allergies - and asthma (as a local inhalation)






19. Nitrate free intervals are needed due to






20. Antihistamine that can be used for anxiety and insomnia and is not addictive






21. The most common neurologic abnormality in chronic alcoholics






22. MOA of neuroleptics






23. Approved for use in severe pulmonary HTN






24. Somatostatin (SRIF) analog used for acromegaly - carcinoid - glucagonoma and other GH producing pituitary tumors






25. Type of kinetics when a constant percentage of substrate is metabolized per unit time






26. Effective in preventing TIA's






27. SE of clonidine






28. Some side effects of corticosteroids






29. Pyrimidine analog that causes 'Thymine - less death' given with leucovorin rescue






30. Heterocyclic antidepressants least likely to affect sexual performance - used for management of nicotine withdrawal - SE's include dizziness - dry mouth - aggravation of psychosis - and seizures






31. Antiarrhythmic effective in most types of arrhythmia






32. Selective alpha agonists that decreases aqueous secretion






33. MOA of repaglinide






34. This step of metabolism makes a drug more hydrophilic and hence augments elimination






35. Agents used in Huntington's Disease






36. Loops lose and thiazide diuretics retain






37. Newer atypical antipsychotics that also improve some of the negative symptoms and help acute agitation






38. Anti - psychotic not shown to cause tardive dyskinesia






39. COX 2 inhibitors should be used cautiously in pts with






40. Drug of choice for leprosy






41. Benzodiazepines that are the most effective in the treatment of panic disorder






42. Reason troglitazone was withdrawn from market






43. Anti - Parkinson's drug which increases intraocular pressure and is contraindicated in closed angle glaucoma






44. Only phenothiazine not exerting antiemetic effects - can cause visual impairment due to retinal deposits - and high doses have been associated with ventricular arrhythmias






45. Selective Alpha -1A blocker - used for BPH - but with little effect on HTN






46. SE of colchicine






47. MOA of thiazolindinediones






48. MOA of cisplatin






49. Antipsychotic used in the treatment of psychiatric symptoms in patients with dementia






50. Interaction with this drug requires dose reduction of 6- MP