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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. SE of minoxidil






2. Distribution of histamine receptors H1 - H2 - and H3






3. Sedation is a common side effect of these drugs - they lower seizure threshold - uses include BAD - acute panic attacks - phobias - enuresis - and chronic pain and their overdose can be deadly






4. Inhibits conversion of cholesterol to pregnenolone therefore inhibiting corticosteroid synthesis






5. Concurrent use of fibrates and statins increases risk of






6. Anti - thyroid drugs






7. Overdoses of this agent with powerful vasoconstrictive action may result in fatalities from arrhythmias - seizures - respiratory depression - or severe HTN (MI and stroke)






8. Pungent inhaled anesthetic which leads to high incidence of coughing and vasospasm






9. Concern using lithium






10. All antidepressants have roughly the same efficacy in treating depression - agents are chosen based on these criterion






11. Anti - psychotic not shown to cause tardive dyskinesia






12. DOC for febrile seizures






13. Thrombolytic that can cause allergic reaction






14. Newer atypical antipsychotics that also improve some of the negative symptoms and help acute agitation






15. Second generation sulfonylurea






16. Amount of drug necessary to elicit a biologic effect; refers to the drug's strength






17. Interferes with activity of T- lymphocytes






18. Antidote used for lead poisoning






19. Dopamine agonist used in hyperprolactinemia






20. Warfarin is contraindicated in






21. Anti - rheumatic agent also used for Chron's disease






22. Drug used in exoerythrocytic cycle of malaria






23. Increased risk of developing cataracts






24. Prevention of cyclophosphamide induced hemorrhagic cystitis






25. Allopurinol treats chronic gout by decreasing uric acid production by inhibiting






26. Can be effective for short term therapy of thyroid storm - but after several weeks of therapy causes an exacerbation of hyperthyroidism






27. The elimination of drug that occurs before it reaches the systemic circulation






28. Intermediate acting glucocorticoids






29. DOC for herpes and its MOA






30. MOA for benzodiazepines






31. SE for ticlopidine






32. Secondary amines that have less sedation and more excitation effect






33. Heparin (PTT) increases activity of






34. Common side effect of hypnotic agents






35. PTU (propylthiouracil) MOA






36. Thrombolytic used for acute MI and ischemic (non hemorrhagic) CVA






37. Reason ergot alkaloids are contraindicated in pregnancy






38. Activation of these receptors open K+ ion channels to cause membrane hyperpolarization






39. IV Drug used Hypertensive Crisis






40. Treatment of resistant pseudomembranous colitis






41. Drugs that can be used for infantile spasms






42. Antipsychotic having the strongest autonomic effects






43. Dose may need to be increased during pregnancy or with Ocs due to increased TBG in plasma






44. Agent that inhibits alcohol dyhydrogenase and its clinical use






45. Used for SIADH






46. Agent to treat torsades de pointes






47. This agent used to treat dry mouth in Sj






48. Barbiturate used for the induction of anesthesia






49. The most toxic organophosphate






50. Antiestrogen drugs used for fertility and breast cancer respectively