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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Cephalosporins able to cross the BBB






2. Newer atypical antipsychotic used for bipolar disorder - known to cause weight gain - and adversely affect diabetes






3. Presynaptic Alpha 2 agonist used in HTN - and acts centrally






4. These beta blockers are less lipid soluble






5. Concentration in the plasma times (clearance divided by bioavailability)






6. Major SE of insulin






7. Meningitis prophylaxis in exposed patients






8. Reduce transient hyper GI motility






9. Slightly increased risk of breast cancer - endometrial cancer - heart disease (questionable) - has beneficial effects on bone loss






10. Beta 1 agonists used in acute CHF






11. Antidepressant having stimulant effects similar to SSRI's and can increase blood pressure






12. Used for hairy cell leukemia; it stimulates NK cells






13. MOA of nateglinide






14. Barbiturates decrease the effectiveness of many other drugs via this pharmacokinetics property






15. Important in muscle and adipose tissue for glucose transport across muscles and TG storage by lipoprotein lipase activation






16. State of analgesia and amnesia produced when fentanyl is used with droperidol and nitrous oxide






17. SE of demeclocycline






18. Most widely used thyroid drugs such as Synthroid and Levoxyl contain






19. MOA of metformin






20. Alpha 1selective blockers






21. Similar to clonidine and may cause hypotension






22. MOA and effect of nitric oxide






23. SE of both warfarin and heparin






24. Selective Alpha -1A blocker - used for BPH - but with little effect on HTN






25. Long acting glucocorticoids






26. Used intranasally and decreases bone resorption






27. Most inhaled anesthetics SE






28. DOC for bipolar affective disorder






29. Hyperglycemic agent that increases cAMP and results in glycogenolysis - gluconeogenesis - reverses hypoglycemia - also used to reverse severe beta - blocker overdose and smooth muscle relaxation






30. Antidepressant with MOA as alpha 2 antagonist - has effects on both 5- HT and NE - blocks histamine receptors - and is sedating






31. Antidote used for warfarin toxicity






32. Antidote for acetaminophen toxicity






33. Drug used in ergot alkaloids overdose - ischemia and gangrene






34. Some of SSRIs' therapeutic effects beside depression






35. Drug used in neuroleptic malignant syndrome






36. Anti - progesterone used as abortifacient






37. Difference between aspirin and other NSAIDS






38. Relates the amount of drug in the body to the plasma concentration






39. Barbiturates MOA






40. Strong opioid agonists






41. Toxicity of these agents include bradycardia - AV blockade - exacerbation of acute CHF; signs of hypoglycemia may be masked (tachycardia - tremor - and anxiety)






42. Inhaled anesthetic with a low blood/gas partition coefficient






43. 5HT-3 antagonist used in chemotherapeutic induced emesis






44. Beta 2 agonist used to suppress premature labor - but cardiac stimulatory effects may be hazardous to mother and fetus






45. Proteins that prevent action of tumor necrosis factor alpha (TNF- alpha)






46. Pneumonic for 3 zones of adrenal cortex






47. Anti - Parkinson's drug which increases intraocular pressure and is contraindicated in closed angle glaucoma






48. Side effect of Mitomycin






49. Clinical use for H2 blockers






50. Treatment of resistant pseudomembranous colitis