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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Barbiturate used for the induction of anesthesia






2. Oral contraceptive available in a transdermal patch






3. Enzyme that metabolizes acetaldehyde to acetate






4. Nonselective alpha agonists that increases outflow - probably via the uveoscleral veins






5. Concentration in the plasma times (clearance divided by bioavailability)






6. Most common SE of fibrates






7. Treatment of patients with prior episodes of thrombocytopenia after a cycle of cancer chemotherapy






8. Fluoride released by metabolism of this inhaled anesthetic may cause renal insufficiency






9. Beta 2 agonist toxicity






10. GnRH antagonist with more immediate effects - used for infertility






11. Alpha agonist used to produce mydriasis and reduce conjunctival itching and congestion caused by irritation or allergy - it does not cause cycloplegia






12. Metronidazole SE if given with alcohol






13. Anti - emetics used in association with anti - cancer drugs that are 5- HT3 (serotonin receptor subtype ) antagonists






14. Diuretic used for mountain sickness and glaucoma






15. Prevents thrombosis in patients with artificial heart valve






16. SSRI with long T1/2 and can be administered once weekly for maintenance - not acute tx






17. Heparin (PTT) increases activity of






18. SE of nesiritide






19. Site of action of thiazide diuretics






20. Fibrates (gemfibrozil) increase activity of






21. Except for these agents all SSRI have significant inhibition of CytP450 enzymes






22. Benzodiazepine that is used for anesthesia






23. SE of phenytoin






24. Common SE of sulfonylureas - repaglinide - and nateglinide






25. Inhaled anesthetics metabolized by liver enzymes which has a major role in the toxicity of these agents






26. Agent having no effect on D2 receptors - blocks D4 - reserved for resistant schizophrenia - and can cause fatal agranulocytosis






27. This beta blocker is highly lipid soluble and may account for side effects such as nightmares






28. Receptors for serotonin (5HT-1) are located






29. This beta blocker lacks local anesthetic activity (a property which decreases protective reflexes and increases the risk of corneal ulceration) and used in treating glaucoma






30. MOA of local anesthetics (LA's)






31. Inhibits conversion of cholesterol to pregnenolone therefore inhibiting corticosteroid synthesis






32. Converts asparagine to aspartate and ammonia - denies cancer cells of essential AA (asparagine)






33. Agent that is a partial agonist for the 5- HT1A receptor






34. Agents used in Tourette's dx






35. Life threatening cardiac event that prolong QT leads to






36. Drug used in Chagas disease






37. Carbamazepine may cause






38. Endogenous insulin contains






39. Arterial vasodilator that works by opening K+ channels






40. Well - tolerated and are first - line antidepressants

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41. Antidote used for warfarin toxicity






42. Site of action for zaleplon and zolpidem






43. SE of both warfarin and heparin






44. Agent to treat hypochromic microcytic anemias






45. Antidote used for lead poisoning






46. SE of long term (>5 days) corticosteroid therapy and remedy






47. Antidote used for anticholinergic poisoning






48. Only phenothiazine not exerting antiemetic effects - can cause visual impairment due to retinal deposits - and high doses have been associated with ventricular arrhythmias






49. Epinephrine is often mixed with a local anesthetic to






50. TCA used in chronic pain - a hypnotic - and has marked antimuscarinic effects






Can you answer 50 questions in 15 minutes?



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