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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Incidence of hyoglycemia with metformin






2. Estrogen mostly used in oral contraceptives (OC)






3. The most frequent cause of acute deaths in cholinesterase inhibitor toxicity






4. Produce mydriasis and cycloplegia






5. Opioid that can be given PO - by epidural - and IV - which helps to relieve the dyspnea of pulmonary edema






6. Agents having higher sedation and antimuscarinic effects than other TCA's






7. Window between therapeutic effect and toxic effect






8. Shock due to septicemia or myocardial infarction is made worse by






9. Example of three antidepressants that are indicated for obsessive compulsive disorder






10. DOC for paroxysmal supraventricular tachycardia (PSVT)






11. Limiting adverse effect of ganglion blockade that patients usually are unable to tolerate






12. Drug increases the renal clearance hence decreases levels of lithium






13. A1a - selective blocker with no effects on HTN used for BPH






14. Agent that inhibits hepatic metabolism - is hepatotoxic and teratogen that can cause neural tube defects and gastrointestinal distress






15. Target plasma concentration times (volume of distribution divided by bioavailability)






16. Drugs available in combination with metformin






17. Indirect - Acting ACh Agonist - alcohol - short DOA and used in diagnosis of myasthenia gravis






18. Antipsychotic used in the treatment of psychiatric symptoms in patients with dementia






19. Sedative - Hypnotics action






20. Mineralocorticoids






21. Readily detected markers that may assist in diagnosis of the cause of a drug overdose include






22. Agent with long duration of action and is most likely to cause histamine release






23. Anti - seizure agent that exhibits non - linear metabolism - highly protein bound - causes fetal hydantoin syndrome - and stimulates hepatic metabolism






24. Plasma concentration of a drug at a given time






25. Triptan available in parenteral and nasal formulation






26. This agent cause increased aqueous outflow






27. Skeletal muscle agent that undergoes Hofmann elimination (breaks down spontaneously)






28. Concern using lithium






29. Anti - androgen used for prostate cancer






30. DOC for malignant hyperthermia that may be caused by use of halogenated anesthetics






31. Beta 2 agonist used to suppress premature labor - but cardiac stimulatory effects may be hazardous to mother and fetus






32. Drug that selectively inhibits COX 2






33. SE of hydroxychloroquine






34. Prostaglandin used in the treatment of impotence






35. Maximum response achieveable from a drug






36. Agent for pernicious anemia






37. Tolerance is marked and abstinence syndrome occurs






38. Common side effect of hypnotic agents






39. Agent similar to cisplatin - less nephrotoxic - but greater myelosuppression






40. Nonselective alpha agonists that increases outflow - probably via the uveoscleral veins






41. Radio contrast media that inhibits the conversion of T4 to T3






42. Bronchodilation in asthma and COPD






43. These agents are used as antitussive






44. Lactam that can be used in PCN allergic patients






45. Time it takes for amount of drug to fall to half of its value; this is a constant in first order kinetics (majority of drugs)






46. 1st generation antihistamine that is least sedating






47. Treatment of choice for organophosphate overdose






48. SE of CCB






49. CCB with predominate effect on arteriole dilation






50. Longer acting benzodiazepines used in the management of withdrawal states of alcohol and other drugs