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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
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  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. SE of minoxidil






2. Antidepressants with no effect on BP - no sedation






3. Important in muscle and adipose tissue for glucose transport across muscles and TG storage by lipoprotein lipase activation






4. Antiarrhythmic effective in most types of arrhythmia






5. Enzyme that metabolizes acetaldehyde to acetate






6. Where are beta cells found in the pancreas?






7. SSRI indicated for premenstrual dysphoric disorder






8. Toxic effect of anticancer drug can be lessened by rescue agents






9. MOA for Ethosuximide






10. Vancomycin MOA






11. Opioid used in the management of withdrawal states






12. A1a - selective blocker with no effects on HTN used for BPH






13. Estrogen mostly used in oral contraceptives (OC)






14. Toxicities include nephrotoxicity and ototoxicity - leading to a severe interaction with aminoglycosides






15. DOC for malignant hyperthermia by acting on the sacroplasmic reticulum or skeletal muscle






16. Amino acid derivative - active as an insulin secretagogue






17. Almost all local anesthetics have this property and sometimes require the administration of vasoconstrictors (ex. Epinephrine) to prolong activity






18. Regimen used for non - Hodgkin's lymphoma






19. MOA for benzodiazepines and barbiturates






20. Concurrent use of fibrates and statins increases risk of






21. Common mechanism by which overdose result in death






22. Opioids used in anesthesia






23. Some side effects of corticosteroids






24. MOA of erythromycin






25. Chemical antagonists that bind to the inhibitor of ACh Estrace and displace the enzyme (if aging has not occurred)






26. One depolarizing blocker that causes continuous depolarization and results in muscle relaxation and paralysis - causes muscle pain postoperatively and myoglobinuria may occur






27. This agent regenerates active cholinesterase and is a chemical antagonist used to treat organophosphate exposure






28. SE of long term (>5 days) corticosteroid therapy and remedy






29. MOA action of cromolyn






30. Scabicide organophosphate






31. Agents acting in the CNS or in the skeletal muscle - used to reduce abnormally elevated tone caused by neurologic or muscle end plate disease






32. Bronchodilation in asthma and COPD






33. 2nd generation antihistamines






34. Anti - seizure drugs used as alternative drugs for mood stabilization






35. Endogenous insulin contains






36. Examples of alpha - glucosidase inhibitors (AGI)






37. MOA of repaglinide






38. Lacrimation - rhinorrhea - yawning - sweating - weakness - gooseflesh - nausea - and vomiting - tremor - muscle jerks - and hyperpnea are signs of this syndrome






39. Mechanisms of action for Phenytoin - Carbamazepine - Lamotrigine






40. Thrombolytic that can cause allergic reaction






41. The most toxic organophosphate






42. Used for Addison's disease - Congenital Adrenal Hyperplasia (CAH) - inflammation - allergies - and asthma (as a local inhalation)






43. Vitamins containing iron should Not be taken simultaneously with levothyroxine because






44. Agent used to treat chronic gout by increasing uric acid secretion and excretion






45. Long acting insulin






46. Weak opioid agonist - poor analgesic - its overdose can cause severe toxicity including respiratory depression - circulatory collapse - pulmonary edema - and seizures






47. Cystitis - postoperative bladder spasms - or incontinence






48. Toxicity caused by nitroprusside and treatment






49. Agent used for megaloblastic anemia (but does Not reverse neurologic symptoms) and decrease neural tube defects during pregnancy






50. Thyroxine dose may need to be increased in hypothyroid patient during pregnancy because







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