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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. SE of Amiodarone






2. Dose may need to be increased during pregnancy or with Ocs due to increased TBG in plasma






3. Only member of depolarizing neuromuscular blocker - causes fasciculation during induction and muscle pain after use; has short duration of action






4. Inhibit angiotensin - converting enzyme (ACE)






5. All antidepressants have roughly the same efficacy in treating depression - agents are chosen based on these criterion






6. Toxic to the liver - kidney - lungs - bone marrow - peripheral nerves - and cause brain damage in animals - sudden death has occurred following inhalation






7. Treatment with cancer chemotherapy at high doses every 3-4 weeks - too toxic to be used continuously






8. Receptors for serotonin (5HT-1) are located






9. MOA of corticosteroids






10. Two toxicities of aminoglycosides






11. DOC for Legionnaires' disease






12. Increased risk of developing cataracts






13. Acetaminophen only has






14. These prevent the action of Ach at the skeletal muscle endplate to produce a 'surmountable blockade -' effect is reversed by cholinesterase inhibitors (ex. neostigmine or pyridostigmine)






15. Technique used to diagnose perianal itching - and the drug used to treat it






16. Benzodiazepine used for anxiety






17. Site of action of loop diuretics






18. Agent that is metabolized to acetaldehyde by alcohol dehydrogenase and microsomal ethanol - oxidizing system (MEOS)






19. Anti - rheumatic agent also used for ulcerative colitis






20. Regimen used for non - Hodgkin's lymphoma






21. Nitrate used to prevent further attacks






22. MOA of tetracycline






23. Beta 1 agonists used in acute CHF






24. Inhaled anesthetic with a low blood/gas partition coefficient






25. Meningitis prophylaxis in exposed patients






26. Beta 2 agonist used to suppress premature labor - but cardiac stimulatory effects may be hazardous to mother and fetus






27. Oral contraceptive available in a transdermal patch






28. MOA of drug or foods (grapefruit juice) that increase statin effect






29. Initial DMARD of choice for patients with RA






30. Antiprogestin used as potent antagonist of GC receptor






31. Most common SE of fibrates






32. All opioids except this agent (which has a muscarinic blocking action) cause pupillary constriction






33. Most common side effect of 1st generation antihistamines






34. Amount of drug necessary to elicit a biologic effect; refers to the drug's strength






35. MOA of sulfonamides






36. Toxicity of these agents include bradycardia - AV blockade - exacerbation of acute CHF; signs of hypoglycemia may be masked (tachycardia - tremor - and anxiety)






37. Class of drugs that may cause cross - sensitivity with thiazide diuretics






38. State of analgesia and amnesia produced when fentanyl is used with droperidol and nitrous oxide






39. Plasma concentration of a drug at a given time






40. MOA of class IV antiarrhythmics






41. Antidote used for cyanide poisoning






42. Additive effects when Sedative - Hypnotics used in combination with these agents






43. Treatment for TB patients (think RIPE)






44. SE of demeclocycline






45. Anabolic steroid that has potential for abuse






46. Agent to treat torsades de pointes






47. Beta 1 agonist toxicity






48. MOA and effect of nitric oxide






49. Agent used for megaloblastic anemia (but does Not reverse neurologic symptoms) and decrease neural tube defects during pregnancy






50. Product of proinsulin cleavage used to assess insulin abuse