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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Antidepressant associated with neuroleptic malignant syndrome






2. Pungent inhaled anesthetic which leads to high incidence of coughing and vasospasm






3. Common mechanism by which overdose result in death






4. Site of action for zaleplon and zolpidem






5. Agents having higher sedation and antimuscarinic effects than other TCA's






6. Increase bone density - also being tested for breast CA prophylaxis






7. Atropine fever is the most dangerous effect and can be lethal in this population group






8. Alternative anticoagulant used if HIT develops






9. Drug used in cancer therapy causes Cushing - like symptoms






10. Used for Addison's disease - Congenital Adrenal Hyperplasia (CAH) - inflammation - allergies - and asthma (as a local inhalation)






11. Leads to respiratory depression progressing to coma and death






12. Lactam that can be used in PCN allergic patients






13. All antidepressants have roughly the same efficacy in treating depression - agents are chosen based on these criterion






14. Longer acting local anesthetics which are less dependent on vasoconstrictors






15. Ergot alkaloid that is a partial agonist at D2 receptors in the brain - used for patients who are refractory or cannot tolerate levodopa - causes erythromelalgia






16. Converts asparagine to aspartate and ammonia - denies cancer cells of essential AA (asparagine)






17. Drugs used in the management of angina






18. Osmotic diuretic used to treat increased intracranial pressure






19. Product of proinsulin cleavage used to assess insulin abuse






20. Metronidazole SE if given with alcohol






21. Example of three antidepressants that are indicated for obsessive compulsive disorder






22. Antipsychotic having the weakest autonomic effects






23. SE of HMG COA reductase inhibitors






24. Diuretic used to treat primary aldosteronism






25. DOC for status epilepticus






26. Antidote used for iron salt toxicity






27. Anti - psychotic not shown to cause tardive dyskinesia






28. Anti - seizure drugs used also for pain of neuropathic orgin






29. This may enhance activity of local anesthetics






30. Anti - seizure drugs used also for Trigeminal neuralgia






31. Amphetamine agents






32. NSAID also available as an ophthalmic preparation






33. Antidote for beta - blockers and hypoglycemia






34. Rapid acting insulins that do not self - aggregate






35. Activation of these receptors close Ca2+ ion channels to inhibit neurotransmitter release






36. Antidote used for lead poisoning






37. Anti - seizure drugs used also for bipolar affective disorder (BAD)






38. Can be effective for short term therapy of thyroid storm - but after several weeks of therapy causes an exacerbation of hyperthyroidism






39. MOA of class I A (eg. Procainamide) - class IB (eg. Lidocaine) - and class IC (eg. Flecainide) antiarrhythmics






40. MOA of nesiritide






41. Major drug interaction with Quinidine






42. Opioid used in the management of withdrawal states






43. Anti - seizure agent that exhibits non - linear metabolism - highly protein bound - causes fetal hydantoin syndrome - and stimulates hepatic metabolism






44. Methylxanthine derivative used as a remedy for intermittent claudication






45. Plasma concentration of a drug at a given time






46. MOA of neuroleptics






47. MOA of both generations






48. Agents used in Tourette's dx






49. These agents are used as antidiarrheal






50. Hormone inhibiting prolactin release