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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Thrombolytics are used for






2. Anti - seizure drugs used also for bipolar affective disorder (BAD)






3. Treatment for TB patients (think RIPE)






4. Side effect of Mitomycin






5. Concentration in the plasma times (clearance divided by bioavailability)






6. Usual time needed for full effect of antidepressant therapy






7. SelectiveB1 Receptor blockers that may be useful in treating patients even though they have asthma






8. Cholestyramine and colestipol are






9. DOC for CMV retinitis






10. Most widely used thyroid drugs such as Synthroid and Levoxyl contain






11. Anti - seizure drugs used as alternative drugs for mood stabilization






12. MOA of Bisphosphonates






13. Short acting glucocorticoids






14. System that increases in activity with chronic ethanol exposure and may contribute to tolerance






15. Activation of these receptors close Ca2+ ion channels to inhibit neurotransmitter release






16. Class of drugs that reversibly inhibit COX






17. Mechanisms of action for Phenytoin - Carbamazepine - Lamotrigine






18. Two toxicities of aminoglycosides






19. Presynaptic Alpha 2 agonist used in HTN - and acts centrally






20. These prevent the action of Ach at the skeletal muscle endplate to produce a 'surmountable blockade -' effect is reversed by cholinesterase inhibitors (ex. neostigmine or pyridostigmine)






21. NSAID contraindicated in gout






22. Four main actions of NSAIDS






23. Barbiturates decrease the effectiveness of many other drugs via this pharmacokinetics property






24. Ergot alkaloid used as an illicit drug






25. Another pneumonic for anticholinergic toxicity

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26. MOA of repaglinide






27. Only phenothiazine not exerting antiemetic effects - can cause visual impairment due to retinal deposits - and high doses have been associated with ventricular arrhythmias






28. Except for these agents all SSRI have significant inhibition of CytP450 enzymes






29. Vascular effects of metformin






30. Prostaglandins that cause abortions






31. 2nd generation antihistamines






32. Enzyme that metabolizes acetaldehyde to acetate






33. Beta 2 agonist toxicity






34. Antibiotic causing red - man syndrome - and prevention






35. Drug of choice for generalized anxiety disorder - Not effective in acute anxiety






36. Weak opioid agonist - poor analgesic - its overdose can cause severe toxicity including respiratory depression - circulatory collapse - pulmonary edema - and seizures






37. Anticoagulant of choice in pregnancy






38. Antidote used for organophosphate/anticholinesterase poisoning






39. Site of action of loop diuretics






40. MOA of both generations






41. Most common SE of fibrates






42. Newer atypical antipsychotics that also improve some of the negative symptoms and help acute agitation






43. Chronic high dose abuse of nicotine leads to






44. Anti - rheumatic agent also used for ulcerative colitis






45. Antidote for acetaminophen toxicity






46. Clinical uses of these agents include treatment of HTN - angina - arrhythmias - chronic CHF - and selected post MI patients






47. Non - benzodiazepine used for sleep






48. COX 2 inhibitors should be used cautiously in pts with






49. MOA of class III antiarrhythmics






50. Beta 1 agonists used in acute CHF