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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. SE of beta blockers






2. Sedative - Hypnotics action






3. Most frequent route of metabolism






4. Angiotensin receptor blockers do Not cause






5. These prevent the action of Ach at the skeletal muscle endplate to produce a 'surmountable blockade -' effect is reversed by cholinesterase inhibitors (ex. neostigmine or pyridostigmine)






6. These beta blockers are less lipid soluble






7. Prostaglandin used in the treatment of impotence






8. 5 alpha - reductase inhibitor used for benign prostatic hyperplasia (BPH) and male pattern baldness






9. Reduced seizure threshold






10. Inhaled anesthetic that may sensitize the myocardium to arrhythmogenic effects of catecholamines and has produced hepatitis






11. Additive effects when Sedative - Hypnotics used in combination with these agents






12. Difference between aspirin and other NSAIDS






13. Block glycoprotein IIb/IIIa involved in platelet cross - linking






14. SE of acetaminophen






15. Agents that block L- type calcium channel






16. MOA of Cardiac glycosides (eg. digoxin)






17. Digoxin toxicity can be precipitated by






18. Thioamide less likely to cross placenta - inhibits peripheral conversion of T4 to T3 in high doses - and should be used with extreme caution in pregnancy






19. Used for SIADH






20. MOA for Valproic acid at high doses






21. Heterocyclic antidepressants least likely to affect sexual performance - used for management of nicotine withdrawal - SE's include dizziness - dry mouth - aggravation of psychosis - and seizures






22. Anti - androgen used for hirsutism in females






23. Drug used for N. gonorrhea in females






24. SSRI indicated for premenstrual dysphoric disorder






25. Prolonged exposure to this inhaled anesthetic may lead to megaloblastic anemia






26. Slightly increased risk of breast cancer - endometrial cancer - heart disease (questionable) - has beneficial effects on bone loss






27. Agent used in CHF that is a selective alpha and nonselective beta blocker






28. Most common side effect of 1st generation antihistamines






29. Biguanide






30. SE of heparin






31. Facilitates GABA presynaptic inhibition






32. Ability to bind reversibly to the same site as the drug and without activating the effector system






33. SE of niacin






34. SSRI less likely to cause a withdrawal syndrome






35. Antiarrhythmic that exhibits Class II and III properties






36. Treat manifestations of Parkinson's disease and EPS






37. Irreversible condition resulting from the use of antipsychotics - reserpine at high doses - and MPTP (by- product of illicit meperidine analog)






38. Effective in preventing TIA's






39. Barbiturates MOA






40. Non - depolarizing skeletal muscle antagonist that has short duration






41. Major SE of zileuton






42. Limiting adverse effect of ganglion blockade that patients usually are unable to tolerate






43. Inhaled anesthetic causes peripheral vasodilation






44. Site of action of thiazide diuretics






45. Used intravenously for acute arrhythmias during surgery






46. Common mechanism by which overdose result in death






47. Dose may need to be increased during pregnancy or with Ocs due to increased TBG in plasma






48. MOA of nystatin






49. The fraction of administered dose of a drug that reaches systemic circulation






50. This agent cause increased aqueous outflow