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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Cephalosporins Not able to cross the BBB






2. Some of SSRIs' therapeutic effects beside depression






3. Specific pharmacokinetic characteristic of amiodarone






4. Inhibitor of leukotrienes (LTD4) receptors and used in asthma






5. The most frequent cause of acute deaths in cholinesterase inhibitor toxicity






6. Inhaled anesthetic with a low blood/gas partition coefficient






7. Antidote for tissue plasminogen activator (t - PA) - streptokinase






8. The most toxic organophosphate






9. NSAID available orally - IM and ophthalmically






10. This diuretic decreases aqueous secretion due to lack of HCO3- ion. Causes drowsiness and paresthesias - alkalinization of the urine may precipitate calcium salts - hypokalemia - acidosis






11. Reason benzos are used cautiously in pregnancy






12. Mineralocorticoids






13. 1st generation antihistamine that is highly sedating






14. Examples of alpha - glucosidase inhibitors (AGI)






15. MOA of colchicine (used in acute gout)






16. Agents for reduction of postpartum bleeding






17. Angiotensin receptor blockers do Not cause






18. Major SE of bisphosphonates






19. MOA of aspirin






20. Chronic high dose abuse of nicotine leads to






21. Antidote useful for some drug induced Torsade de pointes






22. Antidote used for acetaminophen (APAP) toxicity






23. SE of lithium






24. Antidote to benzodiazepine overdose (antagonist that reverses the CNS effects)






25. Incidence of hyoglycemia with metformin






26. Reason ergot alkaloids are contraindicated in pregnancy






27. Sedation is a common side effect of these drugs - they lower seizure threshold - uses include BAD - acute panic attacks - phobias - enuresis - and chronic pain and their overdose can be deadly






28. Treatment of choice for organophosphate overdose






29. Presynaptic Alpha 2 agonist used in HTN - and acts centrally






30. Drug of choice for leprosy






31. Major effect of benzodiazepines on sleep at high doses






32. Tolerance is marked and abstinence syndrome occurs






33. Alpha 1selective blockers






34. Newer atypical antipsychotic used for bipolar disorder - known to cause weight gain - and adversely affect diabetes






35. Major SE of insulin






36. SE of methyldopa


37. Endogenous substances commonly interpreted as histamine - serotonin - prostaglandins - and vasoactive peptides






38. Four main actions of NSAIDS






39. The ratio of the rate of elimination of a drug to its plasma concentration






40. Lacrimation - rhinorrhea - yawning - sweating - weakness - gooseflesh - nausea - and vomiting - tremor - muscle jerks - and hyperpnea are signs of this syndrome






41. Common SE of spironolactone






42. Drug that selectively inhibits COX 2






43. Drug that causes contraction of the uterus






44. DOC for febrile seizures






45. TCA with greatest sedation of this group - and marked antimuscarinic effects - used for sleep






46. Chelating agent used in Wilson's disease






47. DOC for malignant hyperthermia by acting on the sacroplasmic reticulum or skeletal muscle






48. Beta 1 agonists used in acute CHF






49. Alpha 1 agonist toxicity






50. These Beta blockers decrease aqueous secretion