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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Most frequent route of metabolism






2. Withdrawal from this drug causes lethargy - irritability - and headache






3. Antihistamine that can be used for anxiety and insomnia and is not addictive






4. MOA of thiazide diuretics






5. Treatment for TB patients (think RIPE)






6. SE of penicillamine






7. Agent with long duration of action and is most likely to cause histamine release






8. SE of mirtazapine






9. Heterocyclic antidepressants least likely to affect sexual performance - used for management of nicotine withdrawal - SE's include dizziness - dry mouth - aggravation of psychosis - and seizures






10. Important in muscle and adipose tissue for glucose transport across muscles and TG storage by lipoprotein lipase activation






11. Drug of choice for leprosy






12. Chelating agent used in Wilson's disease






13. Some side effects of corticosteroids






14. Osmotic diuretic used to treat increased intracranial pressure






15. SSRI indicated for premenstrual dysphoric disorder






16. Increased risk of developing cataracts






17. MOA of class III antiarrhythmics






18. Only phenothiazine not exerting antiemetic effects - can cause visual impairment due to retinal deposits - and high doses have been associated with ventricular arrhythmias






19. Agents that block L- type calcium channel






20. Agent used for acute muscle spasm






21. Inhalant anesthetics






22. Antidote used for carbon monoxide poisoning






23. Agents having higher sedation and antimuscarinic effects than other TCA's






24. 'Date rape drug'






25. Vitamin given with calcium to ensure proper absorption






26. These beta blockers are less lipid soluble






27. Antidote useful for some drug induced Torsade de pointes






28. The selective agents loose their selectivity at






29. Long acting beta 2 agonist used in asthma






30. Regimen used for non - Hodgkin's lymphoma






31. Antiprogestin used as potent antagonist of GC receptor






32. Side effects seen with tricyclic antidepressants






33. Second generation sulfonylurea






34. Antipsychotics that reduce positive symptoms only






35. Diuretic used to antagonize aldosterone receptors






36. Antifungal agent used for inhibition of all gonadal and adrenal steroids






37. These drugs strongly potentiate and prolong effect of neuromuscular blockade (NMB)






38. H1 antagonist used in motion sickness






39. SE for ticlopidine






40. Mineralocorticoids






41. Interaction with this drug requires dose reduction of 6- MP






42. MOA of metformin






43. This agent regenerates active cholinesterase and is a chemical antagonist used to treat organophosphate exposure






44. Side effect of sotalol






45. SE of hydroxychloroquine






46. This agent used to treat dry mouth in Sj






47. Sympathetic agent which stimulates heart rate and can dilate vessels in skeletal muscle at low doses






48. Inhaled anesthetics metabolized by liver enzymes which has a major role in the toxicity of these agents






49. Antipsychotic having the strongest autonomic effects






50. Treatment for opioid addiction