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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. MOA of class I A (eg. Procainamide) - class IB (eg. Lidocaine) - and class IC (eg. Flecainide) antiarrhythmics






2. Prostaglandin used in the treatment of impotence






3. SE of alpha blockers






4. Diuretic used to treat primary aldosteronism






5. MOA of cisplatin






6. 2nd generation antihistamines






7. This agent cause increased aqueous outflow






8. Reduced seizure threshold






9. All opioids except this agent (which has a muscarinic blocking action) cause pupillary constriction






10. SE of hydralazine






11. Antipsychotics that reduce positive symptoms only






12. SE of methyldopa

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13. Anti - microbials that cause hemolysis in G6PD- deficient patients






14. MOA of aspirin






15. SSRI less likely to cause a withdrawal syndrome






16. Beta blockers work in CHF by






17. Antidote to reverse actions of heparin






18. Concentration in the plasma times (clearance divided by bioavailability)






19. Chelating agent used in acute iron toxicity






20. Agent used to treat MI and to reduce incidence of subsequent MI






21. Cholinomimetics that increase outflow - open trabecular meshwork - and cause ciliary muscle contraction






22. Major SE of bisphosphonates






23. SSRI indicated for premenstrual dysphoric disorder






24. MOA of class III antiarrhythmics






25. Drug that causes contraction of the uterus






26. Treatment with cancer chemotherapy at high doses every 3-4 weeks - too toxic to be used continuously






27. Drug used supraventricular arrhythmias






28. Antidote used for digitalis toxicity






29. MOA of nystatin






30. Cardioselective Beta 1- blockers






31. Agents that reduce heart rate - contractility - and O2 demand






32. Occurs when sedative hypnotics are used chronically or at high doses






33. One depolarizing blocker that causes continuous depolarization and results in muscle relaxation and paralysis - causes muscle pain postoperatively and myoglobinuria may occur






34. Alkylating agent - vesicant that causes tissue damage with extravasation






35. PTU (propylthiouracil) MOA






36. Drug of choice for generalized anxiety disorder - Not effective in acute anxiety






37. A hormone whose MOA utilizes transmembrane receptors






38. Selectivity of a drug for its receptor






39. Antidote used for acetaminophen (APAP) toxicity






40. These Beta blockers decrease aqueous secretion






41. Antivirals that are teratogens






42. Patients being treated with lithium - who are dehydrated - or taking diuretics concurrently - could develop






43. Drug notorious for causing pseudomembranous colitis






44. Anti - Parkinson's drug which increases intraocular pressure and is contraindicated in closed angle glaucoma






45. Agent decreases the excitatory actions of cholinergic neurons. May improve tremor and rigidity but have LITTLE effect on bradykinesia. Atropine - like side effects






46. Opioid available trans - dermally






47. Carbamate with intermediate action - used for+A1170 postoperative and neurogenic ileus and urinary retention






48. Some side effects of corticosteroids






49. All antidepressants have roughly the same efficacy in treating depression - agents are chosen based on these criterion






50. This beta blocker lacks local anesthetic activity (a property which decreases protective reflexes and increases the risk of corneal ulceration) and used in treating glaucoma