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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Antidepressant inhibiting norepinephrine - serotonin - and dopamine reuptake






2. Atropine fever is the most dangerous effect and can be lethal in this population group






3. Selectivity of a drug for its receptor






4. This beta blocker is highly lipid soluble and may account for side effects such as nightmares






5. Another pneumonic for anticholinergic toxicity

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6. Ergot alkaloid that is a partial agonist at D2 receptors in the brain - used for patients who are refractory or cannot tolerate levodopa - causes erythromelalgia






7. Selective alpha agonists that decreases aqueous secretion






8. Most commonly abused in health care professionals






9. Antiprogestin used as potent antagonist of GC receptor






10. Toxicity caused by nitroprusside and treatment






11. Generation of antihistamine that has the most CNS effects






12. Example of three antidepressants that are indicated for obsessive compulsive disorder






13. 'Date rape drug'






14. Meningitis prophylaxis in exposed patients






15. Irreversible - nonselective COX inhibitor






16. MOA of nateglinide






17. The most common neurologic abnormality in chronic alcoholics






18. SE of nitrates






19. Aminoglycoside that is least ototoxic






20. Antidote used for tricyclic antidepressants (TCA)






21. Class of drugs with ability to decrease the maximal response to an agonist






22. Drug that causes contraction of the uterus






23. Drugs used in the management of angina






24. Antidote used for anticholinergic poisoning






25. Available bisphosphonates






26. Prevents thrombosis in patients with artificial heart valve






27. Strength of interaction between drug and its receptor






28. Anti - viral with a dose limiting toxicity of pancreatitis






29. MOA for benzodiazepines and barbiturates






30. Sulfonylurea Not recommended for elderly because of very long half life






31. Class of anti - arrhythmics that has a pro - arrhythmic effect (CAST trial) - therefore are used as last line agents






32. IV Drug used Hypertensive Crisis






33. Organophosphate anthelmintic agent with long DOA






34. MOA of aspirin






35. Beta 2 agonist used to suppress premature labor - but cardiac stimulatory effects may be hazardous to mother and fetus






36. Agents for reduction of postpartum bleeding






37. Well - tolerated and are first - line antidepressants

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38. THC is active ingredient - SE's include impairment of judgment - and reflexes - decreases in blood pressure and psychomotor performance occur






39. 5HT-3 antagonist that has been associated with QRS and QTc prolongation and should not be used in patients with heart disease






40. Phenylisopropylamines that are used legitimately and abused for narcolepsy - attention deficit disorder - and weight reduction






41. Reason troglitazone was withdrawn from market






42. Alpha - glucosidase inhibitor associated with elevation of LFT's






43. This is the drug of choice for anaphylactic shock






44. Anti - microbials that cause hemolysis in G6PD- deficient patients






45. This parenteral beta blocker is a short acting (minutes)






46. Inhibitor of MAO type B which metabolizes dopamine - used adjunct to levodopa or as sole agent in newly diagnosed patients






47. Prevention of cyclophosphamide induced hemorrhagic cystitis






48. Anti - androgen used for hirsutism in females






49. SE of phenytoin






50. Concentration in the plasma times (clearance divided by bioavailability)