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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Plasma concentration of a drug at a given time






2. Aspirin reduces mortality in unstable angina by






3. Pneumonic for beta receptors






4. Laboratory value required to be monitored for patients on valproic acid

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5. T3 compound less widely used






6. Toxic effect of anticancer drug can be lessened by rescue agents






7. Anti - rheumatic agent also used for ulcerative colitis






8. What do alpha cells in the pancreas produce?






9. Non - benzodiazepine used as an anxiolytic






10. Dose may need to be increased during pregnancy or with Ocs due to increased TBG in plasma






11. Associated with an increased incidence of cataracts in patients treated for glaucoma






12. Antidote used for tricyclic antidepressants (TCA)






13. Thrombolytic used for acute MI and ischemic (non hemorrhagic) CVA






14. Inhibitor of leukotrienes (LTD4) receptors and used in asthma






15. Enhances dopaminergic neurotransmission SE's include CNS excitation - acute toxic psychosis and livedo reticularis






16. Class of anti - arrhythmics that has a pro - arrhythmic effect (CAST trial) - therefore are used as last line agents






17. Phenylisopropylamines that are used legitimately and abused for narcolepsy - attention deficit disorder - and weight reduction






18. Antidote used for acetaminophen (APAP) toxicity






19. Anti - seizure agent that induces formation of liver drug - metabolism enzymes - is teratogen and can cause craniofacial anomalies and spina bifida






20. MOA of cisplatin






21. W/D from this drug causes anxiety and mental discomfort






22. 3 zones of adrenal cortex and their products






23. All opioids except this agent (which has a muscarinic blocking action) cause pupillary constriction






24. Anti - biotic frequently used for chronic UTI prophylaxis






25. Major SE of zileuton






26. Common toxicities of cisplatin






27. Heparin (PTT) increases activity of






28. Non - benzodiazepine used for sleep






29. Agent with zero - order kinetics






30. Class of drugs whose MOA utilizes ligand gated ion channels






31. This beta blocker is highly lipid soluble and may account for side effects such as nightmares






32. Inhibitor of lipoxygenase






33. This agent cause increased aqueous outflow






34. Antidote for methotrexate toxicity






35. Route of administration of warfarin






36. Anti - viral agents associated with Stephen Johnson syndrome






37. Losartan and valsartan block






38. Beta blockers partial agonist activity (intrinsic sympathomimetic activity) cause some bronchodilation and may have an advantage in treating patients with asthma






39. Common SE of spironolactone






40. Causes bone marrow suppression






41. Antidote used for carbon monoxide poisoning






42. Chelating agent used in acute iron toxicity






43. SE of acetazolamide






44. Antidote used for organophosphate/anticholinesterase poisoning






45. Barbiturates decrease the effectiveness of many other drugs via this pharmacokinetics property






46. Agent used in CHF that is a selective alpha and nonselective beta blocker






47. MOA of thrombolytics






48. Relates the amount of drug in the body to the plasma concentration






49. Drug that selectively inhibits COX 2






50. Treatment of resistant pseudomembranous colitis