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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
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  • Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Treat manifestations of Parkinson's disease and EPS






2. These agents are used as antidiarrheal






3. Somatostatin (SRIF) analog used for acromegaly - carcinoid - glucagonoma and other GH producing pituitary tumors






4. Alpha 1 agonist toxicity






5. Incidence of hyoglycemia with metformin






6. Prevents thrombosis in patients with artificial heart valve






7. CCB contraindicated in CHF






8. This agent used to treat dry mouth in Sj






9. Agent used for acute muscle spasm






10. ACTH analog used for diagnosis of patients with corticosteroid abnormality






11. GHRH analog used as diagnostic agent






12. Most widely used thyroid drugs such as Synthroid and Levoxyl contain






13. Lithium is associated with this congenital defect






14. DOC for Legionnaires' disease






15. Peakless ling acting insulin






16. Long acting sympathomimetic - sometimes used to improve urinary continence in children and elderly with enuresis






17. MOA of both generations






18. This produces 'dissociative anesthesia' - is a cardiovascular stimulant which may increases intracranial pressure - and hallucinations occur during recovery






19. Relates the amount of drug in the body to the plasma concentration






20. Some cell cycle specific anti - cancer drugs






21. Antidepressant also used for sleep that causes priapism






22. MOA of corticosteroids






23. Intermediate acting glucocorticoids






24. This is combined with L- dopa - inhibits DOPA decarboxylase (active only peripherally) which allows lower effective doses of L- dopa and allows for fewer SE's (GI distress - postural hypotension - and dyskinesias)






25. NSAID also available as an ophthalmic preparation






26. SE of beta blockers






27. Potassium sparing diuretics inhibit






28. Common SE of tamoxifen and raloxifene






29. Inhibits conversion of cholesterol to pregnenolone therefore inhibiting corticosteroid synthesis






30. Inhibitor of leukotrienes (LTD4) receptors and used in asthma






31. Regimen used for non - Hodgkin's lymphoma






32. Agent that is a partial agonist for the 5- HT1A receptor






33. Constant proportion of cell population killed rather than a constant number






34. Thiazolidinediones






35. Biguanide






36. Opioid that can be given PO - by epidural - and IV - which helps to relieve the dyspnea of pulmonary edema






37. Non - benzodiazepine used as an anxiolytic






38. Treatment of myasthenia gravis






39. Rapid acting - crystalline zinc insulin used to reverse acute hyperglycemia






40. First generation sulfonylurea






41. Sedation is a common side effect of these drugs - they lower seizure threshold - uses include BAD - acute panic attacks - phobias - enuresis - and chronic pain and their overdose can be deadly






42. MOA of metformin






43. ADH agonist used for pituitary diabetes insipidus






44. Very rapid acting insulin - having fastest onset and shortest duration of action






45. TCA used in chronic pain - a hypnotic - and has marked antimuscarinic effects






46. Newer estrogen receptor antagonist used in advanced breast cancer






47. Treatment of atropine overdose and glaucoma (because lipid soluable). Enters the CNS rapidly and has a stimulant effect - which may lead to convulsions






48. Inhaled anesthetic - less likely to lower blood pressure than other agents - and has the smallest effect on respiration






49. Benzodiazepine receptor antagonist - it accelerates recovery from benzodiazepine overdose






50. Aspirin reduces mortality in unstable angina by







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