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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
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  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Atropine fever is the most dangerous effect and can be lethal in this population group






2. Activation of these receptors open K+ ion channels to cause membrane hyperpolarization






3. TCA with greatest sedation of this group - and marked antimuscarinic effects - used for sleep






4. Drugs of choice for status epilepticus






5. LA causing methemoglobinemia






6. Dose may need to be increased during pregnancy or with Ocs due to increased TBG in plasma






7. State of analgesia and amnesia produced when fentanyl is used with droperidol and nitrous oxide






8. Clinical uses of these agents include treatment of HTN - angina - arrhythmias - chronic CHF - and selected post MI patients






9. ADH agonist used for pituitary diabetes insipidus






10. Drug used for African sleeping sickness






11. Chelating agent used in acute iron toxicity






12. Antidote used for warfarin toxicity






13. Selective Alpha 1 blocker used for hypertension - BPH - may cause first dose orthostatic hypotension






14. SE of imipenem






15. Non - selective Alpha1blockers use to treat pheochromocytoma






16. MOA of class I A (eg. Procainamide) - class IB (eg. Lidocaine) - and class IC (eg. Flecainide) antiarrhythmics






17. Major nutritional side effect of bile acid - binding resins






18. Enhances dopaminergic neurotransmission SE's include CNS excitation - acute toxic psychosis and livedo reticularis






19. 'Date rape drug'






20. H1 antagonist used in motion sickness






21. MOA of erythromycin






22. NSAID that is used for acute condition - such as pre - op anesthesia and has limited duration (<5 days) of use due to nephrotoxicity






23. Anticoagulant of choice in pregnancy






24. Antiprogestin used as potent antagonist of GC receptor






25. MOA of class III antiarrhythmics






26. Products of Phase II conjugation






27. Common side effect of hypnotic agents






28. Diuretic used for mountain sickness and glaucoma






29. Commonly abused LA which has cardiovascular toxicity including severe hypertension with cerebral hemorrhage - cardiac arrhythmias - and myocardial infarction






30. Peptide causing increased capillary permeability and edema






31. Cardioselective Beta 1- blockers






32. Agent used for anemias associated with renal failure






33. Antidote useful for some drug induced Torsade de pointes






34. Benzodiazepines used to promote sleep






35. The fraction of administered dose of a drug that reaches systemic circulation






36. Beta 2 agonist used to suppress premature labor - but cardiac stimulatory effects may be hazardous to mother and fetus






37. SE for Felbamate






38. Other side effects of Quinidine






39. Interact with microtubules (but unlike vinca which prevent disassembly of tubules) - it stabilizes tubulin and cells remain frozen in metaphase






40. 5 alpha - reductase inhibitor used for benign prostatic hyperplasia (BPH) and male pattern baldness






41. Nitroprusside vasodilates






42. Chronic orthostatic hypotension can be treated with






43. Reduced seizure threshold






44. Overdoses of this agent with powerful vasoconstrictive action may result in fatalities from arrhythmias - seizures - respiratory depression - or severe HTN (MI and stroke)

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45. Benzodiazepine that is used for anesthesia






46. Antidote for tissue plasminogen activator (t - PA) - streptokinase






47. Drug used in neuroleptic malignant syndrome






48. Drug causes teeth discoloration






49. Bronchodilation in asthma and COPD






50. HIV antiviral class known to have severe drug interactions by causing inhibition of metabolism







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