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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What do beta cells in the pancreas produce?






2. Intermediate acting glucocorticoids






3. Muscarinic antagonist used in asthma






4. Usual time needed for full effect of antidepressant therapy






5. MOA of sulfonamides






6. Uses of bisphosphonates

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7. Atropine fever is the most dangerous effect and can be lethal in this population group






8. Methylxanthine derivative used as a remedy for intermittent claudication






9. MOA and effect of nitric oxide






10. DOC for herpes and its MOA






11. Common SE of tamoxifen and raloxifene






12. SE of procainamide






13. Lethal arrhythmias resulting from concurrent therapy with azole fungals (metabolized by CYP 3A4) and these antihistamines which inhibit the 3A4 iso - enzyme.






14. MOA of loop diuretics






15. Organophosphate anthelmintic agent with long DOA






16. Agent that inhibits alcohol dyhydrogenase and its clinical use






17. Anti - seizure medication also used in the prevention of migraines






18. Non - selective Beta - blocker also used for migraine prophylaxis






19. Prostaglandins that cause abortions






20. Treatment of myasthenia gravis






21. Agent used in the treatment of alcoholism - if alcohol is consumed concurrently - acetaldehyde builds up and results in nausea - headache - flushing - and hypotension






22. Antidote for hyperkalemia






23. Incidence of hyoglycemia with metformin






24. Lactam that can be used in PCN allergic patients






25. SE seen only in men with administration of ketoconazole






26. Agent which stimulates cardiac contractile force more than rate with little effect on total peripheral resistance






27. Drugs of choice for generalized tonic - clonic and partial seizures






28. Causes acne - premature closure of epiphyses - masculinization in females - hepatic dysfunction - MI - and increases in libido and aggression






29. Drug causes teeth discoloration






30. Major drug interaction with Quinidine






31. Strength of interaction between drug and its receptor






32. Drug of choice for generalized anxiety disorder - Not effective in acute anxiety






33. Short acting Beta 2 agonists that is drug of choice in treatment of acute asthma but not recommended for prophylaxis






34. Beta 2 agonist used to suppress premature labor - but cardiac stimulatory effects may be hazardous to mother and fetus






35. DOC for paroxysmal supraventricular tachycardia; has high efficacy and short duration of action






36. MOA of sildenafil (Viagra)






37. Beta - blockers should be used cautiously in






38. Barbiturate used for the induction of anesthesia






39. Site of action of thiazide diuretics






40. These LA's have surface activity






41. Heterocyclic antidepressants least likely to affect sexual performance - used for management of nicotine withdrawal - SE's include dizziness - dry mouth - aggravation of psychosis - and seizures






42. SE of nitrates






43. Ultra long acting insulin - has over a day duration of action






44. Opioid antagonist that is given IV and had short DOA






45. Technique used to diagnose perianal itching - and the drug used to treat it






46. Inhibitors of CYP450






47. SE of HMG COA reductase inhibitors






48. Tolerance is marked and abstinence syndrome occurs






49. Drug that causes gray baby syndrome and aplastic anemia






50. Partial opioid agonist - considered a strong analgesic - has a long duration of action and is resistant to naloxone reversal