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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Some cell cycle specific anti - cancer drugs






2. Drug of choice for myoclonic seizures






3. Treatment of choice for organophosphate overdose






4. MOA of Bisphosphonates






5. Antiarrhythmic that exhibits Class II and III properties






6. Weak opioid agonist - poor analgesic - its overdose can cause severe toxicity including respiratory depression - circulatory collapse - pulmonary edema - and seizures






7. Acetaminophen only has






8. Long acting beta 2 agonist used in asthma






9. Maximum response achieveable from a drug






10. Type of resistance found with vancomycin






11. Causes bone marrow suppression






12. Alternative anticoagulant used if HIT develops






13. Long acting sympathomimetic - sometimes used to improve urinary continence in children and elderly with enuresis






14. Antidote to benzodiazepine overdose (antagonist that reverses the CNS effects)






15. Some cell cycle non - specific drugs






16. Exogenous insulin contains






17. CCB with predominate effect on arteriole dilation






18. W/D from this drug causes anxiety and mental discomfort






19. Anti - malarial drug used in rheumatoid arthritis (RA)






20. SE of Aspirin






21. GHRH analog used as diagnostic agent






22. Treatment of withdrawal syndrome involves






23. Good hypnotic activity with less CNS SE than most benzodiazepines






24. Thrombolytics are used for






25. Important in synthesis of glucose to glycogen in the liver






26. Ergot alkaloid that is a partial agonist at D2 receptors in the brain - used for patients who are refractory or cannot tolerate levodopa - causes erythromelalgia






27. Sulfonylurea Not recommended for elderly because of very long half life






28. Inhibit angiotensin - converting enzyme (ACE)






29. Primary endogenous substrate for Nitric Oxidase Synthase






30. Most frequent route of metabolism






31. Antidote used for anticholinergic poisoning






32. MOA of nateglinide






33. Route of administration of warfarin






34. SE of acetazolamide






35. Disease caused by excess ergot alkaloids

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36. Prototypical drug is atropine






37. Cholinomimetics that increase outflow - open trabecular meshwork - and cause ciliary muscle contraction






38. Anti - seizure drugs used also for bipolar affective disorder (BAD)






39. Site of action of loop diuretics






40. IV barbiturate used as a pre - op anesthetic






41. MOA of NSAIDS






42. SSRI with long T1/2 and can be administered once weekly for maintenance - not acute tx






43. Radio contrast media that inhibits the conversion of T4 to T3






44. Most common SE of fibrates






45. Commonly abused LA which has cardiovascular toxicity including severe hypertension with cerebral hemorrhage - cardiac arrhythmias - and myocardial infarction






46. Osmotic diuretic used to treat increased intracranial pressure






47. Benzodiazepine used for anxiety






48. Class of drugs with ability to decrease the maximal response to an agonist






49. Agent used in drug therapy of Parkinson's instead of Dopamine which has low bioavailability and does not cross the BBB






50. Inhaled anesthetic causes peripheral vasodilation







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