SUBJECTS
|
BROWSE
|
CAREER CENTER
|
POPULAR
|
JOIN
|
LOGIN
Business Skills
|
Soft Skills
|
Basic Literacy
|
Certifications
About
|
Help
|
Privacy
|
Terms
|
Email
Search
Test your basic knowledge |
USMLE/COMLEX Step 1 Pharmacology One Liners
Start Test
Study First
Subjects
:
health-sciences
,
usmle-step-1
,
comlex
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Agent used in the treatment of alcoholism - if alcohol is consumed concurrently - acetaldehyde builds up and results in nausea - headache - flushing - and hypotension
Disulfiram
Magnesium sulfate
Anti - inflammatory - analgesia - antipyretic and antiplatelet activity
Cocaine
2. Chelating agent used in Wilson's disease
Parathion
Streptomycin
L- asparaginase
Penicillamine
3. Barbiturate used for the induction of anesthesia
'dry as a bone - red as a beet - mad as a hatter - hot as a hare - blind as a bat'
Aminoglutethimide
Thiopental
Cephalosporins
4. Inhaled anesthetic that may sensitize the myocardium to arrhythmogenic effects of catecholamines and has produced hepatitis
Halothane
CNS stimulation; GI upset
Diphenoxylate - Loperamide
Propranolol
5. Antidote to benzodiazepine overdose (antagonist that reverses the CNS effects)
Apraclonidine - brimonidine
Cp
Flumazenil
Odansetron
6. Antidote used for heparin overdose
Overdose of opioids
Protamine
Nadolol
Neuromuscular blocking drugs
7. SE of both warfarin and heparin
Methotrexate
Bleeding
Serotonin syndrome
Hyperprolactinemia - menorrhea - galactorrhea - confusion - mood changes - decreased sexual interest - and weight gain
8. Benzodiazepine that is used for anesthesia
Aplastic anemia and acute hepatic failure
Midazolam
Flatulence (do not use beano to tx) - diarrhea - abdominal cramps
Block cell wall synthesis by inhibiting peptidoglycan cross - linkage
9. Product of proinsulin cleavage used to assess insulin abuse
Ethanol
Calcium channels
C- peptide
Allopurinol
10. Anti - emetics used in association with anti - cancer drugs that are 5- HT3 (serotonin receptor subtype ) antagonists
Ipratropium
Cyanide toxicity treated with sodium thiosulfate
Agranulocytosis
Odansetron - granisetron
11. COX 2 inhibitors should be used cautiously in pts with
Dimercaprol
Methotrexate
Pre - existing cardiac or renal disease
Mirtazapine
12. IV Drug used Hypertensive Crisis
GLUT 4
Nitroprusside
Orthostatic hypotension (especially with first dose) and reflex tachycardia
Valproic acid
13. These Beta blockers decrease aqueous secretion
Carbamazepine
Timolol (nonselective) - betaxolol (selective)
Abstinence syndrome
Flumazenil
14. GABA agonist in the spinal cord
Alprazolam and Clonazepam
Baclofen
Steady state
Vitamin K and Fresh frozen plasma (FFP)
15. Agent used in CHF that is a selective alpha and nonselective beta blocker
Calcium
Disulfiram
Cyanocobalamin (Vit B12)
Carvedilol
16. Most important toxic effects of most local anesthetics
Codeine - hydrocodone - and oxycodone
CNS toxicity
CNS stimulation; GI upset
Diazepam - Flurazepam - chlordiazepoxide - and clorazepate
17. The most common neurologic abnormality in chronic alcoholics
Sulfonamides
Peripheral neuropathy (also excessive alcohol use is associated with HTN - anemia - and MI)
Estogens increase maternal TBG
Penicillamine
18. Treatment of patients with prior episodes of thrombocytopenia after a cycle of cancer chemotherapy
Ondansetron - granisetron - dolasetron and alosetron
Liver enzyme INDUCTION
Interleukin 11 (oprelvekin)
Odansetron - granisetron
19. Diuretic used to antagonize aldosterone receptors
Spironolactone
Reduce inhibition - suppress anxiety - and produce relaxation
Cyclobenzaprine
Volume of distribution (VD)
20. Anticoagulant of choice in pregnancy
Inhibits phosphodiesterase -5 - enhancing effects of nitric oxide - activated increases in cGMP
Heparin
Insulin
Older antipsychotic agents - D2 receptors
21. Blows DNA (breaks DNA strands) - limiting SE is pulmonary fibrosis
Cholinesterase regenerators - pralidoxime
Nitrous oxide
Bleomycin
Radioactive iodine
22. MOA of lovastatin (STATIN)
Prostaglandin E1 (misoprostol) PGE2 - and PGF2alpha
inhibits HMG COA reductase
Tolerance
Aspirin - metoprolol
23. Radio contrast media that inhibits the conversion of T4 to T3
Nonselective Muscarinic Antagonists
Metronidazole
Ipodate
Mechlorethamine
24. Use of this opioid with MAOI can lead to hyperpyrexic coma - and with SSRI's can lead to serotonin syndrome
Metronidazole
Geriatrics due to its CNS (depression) effects
Methotrexate
Meperidine
25. Approved for use in severe pulmonary HTN
Folic acid
Drug induced Parkinsonism
Increases concentration of Digoxin
PGI2 (epoprostenol)
26. Endogenous substances commonly interpreted as histamine - serotonin - prostaglandins - and vasoactive peptides
Cholinesterase inhibitors
Prostaglandin PGF2a
Autocoids
Nephro and ototoxicity
27. Drug of choice for leprosy
Pulmonary embolism and DVT
Diphendydramine
Minocycline
Dapsone - rifampin and clofazimine combination
28. SE of minoxidil
Gingival hyperplasia - nystagmus - diplopia and ataxia
AZT (zidovudine)
Hypertrichosis
Rifampin
29. Reason troglitazone was withdrawn from market
Hyperprolactinemia - menorrhea - galactorrhea - confusion - mood changes - decreased sexual interest - and weight gain
Inhibiting dihydroorotate dehydrogenase which leads to decreased pyrimidine synthesis - decreased T cell proliferation and decreased antibody production by B cells
Ascending pathways
Hepatic toxicity
30. Agent used for closure of patent ductus arteriosus
Indomethacin
Glucagon
Pindolol and acebutolol
Odansetron - granisetron
31. Toxic effect of anticancer drug can be lessened by rescue agents
Full agonist
Normal C- peptide
Valproic acid
Rescue therapy
32. Meglitinide class of drugs
GFR
Repaglinide
Sumatriptan - naratriptan - and rizatriptan
Naltrexone
33. Causes bone marrow suppression
Thyroid and steroid hormones
Point mutation
Iron deiodinates thyroxine
Methotrexate
34. Used intranasally and decreases bone resorption
Naloxone
Calcitonin (salmon prep)
Sotalol
'On - off - phenomenon'
35. Syndrome of hypersecretion of gastric acid and pepsin usually caused by gastrinoma; it is associated with severe peptic ulceration and diarrhea
Infants - closed angle glaucoma - prostatic hypertrophy
Zollinger - Ellison Syndrome
Desmopressin (DDAVP)
Meperidine
36. Class III antiarrhythmic that exhibits properties of all 4 classes
Haloperidol
Amiodarone
Hypoglycemia
Postsynaptic Mu receptors
37. Concentration in the plasma times (clearance divided by bioavailability)
Maintenance dose (Cp*(CL/F))
6- mercaptopurine (6- MP)
Prinzmetal's angina
Albuterol
38. Aspirin reduces mortality in unstable angina by
Chlorpropamide - tolbutamide - tolazamide - etc.
Hepatic toxicity
Platelet aggregation inhibition
Epinephrine
39. Arterial vasodilator that works by opening K+ channels
Minoxidil
Scotch tape technique and mebendazole
Morphine - methadone - meperidine - and fentanyl
Flumazenil
40. Antidote used for anticholinergic poisoning
Somatrem
Dantrolene
Physostigmine
Ability to cross the placenta
41. Carbamate with intermediate action - used for+A1170 postoperative and neurogenic ileus and urinary retention
Hepatic enzymes
Corticosteroids
Neostigmine
Regular (Humulin R)
42. Good hypnotic activity with less CNS SE than most benzodiazepines
Metronidazole
Zolpidem - zaleplon
Ethanol
Arteries and veins
43. Anti - biotic frequently used for chronic UTI prophylaxis
Letrozole - anastrozole
Olanzapine - aripiprazole - and sertindole
sulfamethoxazole/ trimethoprim
Iodide salts
44. Agent which stimulates cardiac contractile force more than rate with little effect on total peripheral resistance
Dobutamine
Tamoxifen
SEVERE myelosuppression
Bromocriptine
45. Specific pharmacokinetic characteristic of amiodarone
Clomipramine - fluoxetine and fluvoxamine
Prolonged half - life - up to six weeks
Diazepam
Hepatic toxicity
46. Digoxin is used in
ED50
Atrial fibrillation and CHF
Terbutaline
Chemical esophagitis
47. SE of hydroxychloroquine
Retinal destruction and dermatitis
Valproic acid
Hot flashes
DUMBELSS (diarrhea - urination - miosis - bronchoconstriction - excitation of skeletal muscle and CNS - lacrimation - salivation - and sweating)
48. Initial DMARD of choice for patients with RA
Clindamycin
Methotrexate
Hydration and mercaptoethanesulfonate (MESNA)
Benzodiazepine receptor BZ1 (although do not have a benzodiazepine ring structure)
49. Drug that causes gray baby syndrome and aplastic anemia
Panic attacks - social phobias - bulimia nervosa - and PMDD (premenstrual dysphoric disorder) - OCD
Constipation - edema - and headache
Chloramphenicol
Testosterone
50. This produces 'dissociative anesthesia' - is a cardiovascular stimulant which may increases intracranial pressure - and hallucinations occur during recovery
Hypoglycemia
Ketamine
Odansetron
IV administration
Sorry!:) No result found.
Can you answer 50 questions in 15 minutes?
Let me suggest you:
Browse all subjects
Browse all tests
Most popular tests
Major Subjects
Tests & Exams
AP
CLEP
DSST
GRE
SAT
GMAT
Certifications
CISSP go to https://www.isc2.org/
PMP
ITIL
RHCE
MCTS
More...
IT Skills
Android Programming
Data Modeling
Objective C Programming
Basic Python Programming
Adobe Illustrator
More...
Business Skills
Advertising Techniques
Business Accounting Basics
Business Strategy
Human Resource Management
Marketing Basics
More...
Soft Skills
Body Language
People Skills
Public Speaking
Persuasion
Job Hunting And Resumes
More...
Vocabulary
GRE Vocab
SAT Vocab
TOEFL Essential Vocab
Basic English Words For All
Global Words You Should Know
Business English
More...
Languages
AP German Vocab
AP Latin Vocab
SAT Subject Test: French
Italian Survival
Norwegian Survival
More...
Engineering
Audio Engineering
Computer Science Engineering
Aerospace Engineering
Chemical Engineering
Structural Engineering
More...
Health Sciences
Basic Nursing Skills
Health Science Language Fundamentals
Veterinary Technology Medical Language
Cardiology
Clinical Surgery
More...
English
Grammar Fundamentals
Literary And Rhetorical Vocab
Elements Of Style Vocab
Introduction To English Major
Complete Advanced Sentences
Literature
Homonyms
More...
Math
Algebra Formulas
Basic Arithmetic: Measurements
Metric Conversions
Geometric Properties
Important Math Facts
Number Sense Vocab
Business Math
More...
Other Major Subjects
Science
Economics
History
Law
Performing-arts
Cooking
Logic & Reasoning
Trivia
Browse all subjects
Browse all tests
Most popular tests