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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
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  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. MOA of tetracycline






2. Agents used in treatment of carcinoid tumor






3. Alpha 1 agonist toxicity






4. Agent more frequently associated with extrapyramidal side effects that can be treated with benzodiazepine - diphenhydramine or muscarinic blocker






5. Adenosine's MOA






6. Non - depolarizing skeletal muscle antagonist that has short duration






7. Side effects occuring in antipsychotics that block dopamine






8. Treat manifestations of Parkinson's disease and EPS






9. SE for Lamotrigine






10. Somatostatin (SRIF) analog used for acromegaly - carcinoid - glucagonoma and other GH producing pituitary tumors






11. Drug is used with testosterone for male fertility






12. Antidote used for organophosphate/anticholinesterase poisoning






13. Agent that is metabolized to acetaldehyde by alcohol dehydrogenase and microsomal ethanol - oxidizing system (MEOS)






14. TCA used in chronic pain - a hypnotic - and has marked antimuscarinic effects






15. Vancomycin MOA






16. Population group especially sensitive to side effects of antidepressants






17. PTU (propylthiouracil) MOA






18. SE of imipenem






19. Rapid acting - crystalline zinc insulin used to reverse acute hyperglycemia






20. Mediator of tissue pain - edema - inactivated by ACE - and may be a contributing factor to the development of angioedema






21. Angiotensin receptor blockers do Not cause






22. MOA and effect of nitric oxide






23. Concentration in the plasma times (clearance divided by bioavailability)






24. The fraction of administered dose of a drug that reaches systemic circulation






25. SE of salicylates






26. Important in synthesis of glucose to glycogen in the liver






27. Antiprogestin used as potent antagonist of GC receptor






28. Major effect of benzodiazepines on sleep at high doses






29. A hormone whose mechanism of action (MOA) utilizes intracellular receptors






30. W/D from this drug causes anxiety and mental discomfort






31. Inhaled anesthetics metabolized by liver enzymes which has a major role in the toxicity of these agents






32. Opioid that can be given PO - by epidural - and IV - which helps to relieve the dyspnea of pulmonary edema






33. Very rapid acting insulin - having fastest onset and shortest duration of action






34. Associated with an increased incidence of cataracts in patients treated for glaucoma






35. Bleomycin+vinblastine+etoposide+cisplatin produce almost a 100% response when all agents are used for this neoplasm






36. SE of nitrates






37. Mechanisms of action for Phenytoin - Carbamazepine - Lamotrigine






38. Blows DNA (breaks DNA strands) - limiting SE is pulmonary fibrosis






39. SelectiveB1 Receptor blockers that may be useful in treating patients even though they have asthma






40. DOC for influenza A






41. Most frequent route of metabolism






42. Patients being treated with lithium - who are dehydrated - or taking diuretics concurrently - could develop






43. This beta blocker is highly lipid soluble and may account for side effects such as nightmares






44. Anti - arrhythmics that decrease mortality






45. Antidote used for heparin overdose






46. Second generation sulfonylurea






47. Maximum response achieveable from a drug






48. Cutaneous flush and be reduced by pretreatment with






49. Benzodiazepines that are the most effective in the treatment of panic disorder






50. The ratio of the rate of elimination of a drug to its plasma concentration






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