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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Diuretic used to antagonize aldosterone receptors






2. DMARDs are slow acting drugs for






3. Maximum response achieveable from a drug






4. Agents used in treatment of carcinoid tumor






5. Rapid acting - crystalline zinc insulin used to reverse acute hyperglycemia






6. This agent may cause more severe - rapid and intense symptoms to a recovering addict






7. Toxicities include nephrotoxicity and ototoxicity - leading to a severe interaction with aminoglycosides






8. Similar to clonidine and may cause hypotension






9. SE of salicylates






10. Adenosine's MOA






11. Anti - seizure drugs used also for bipolar affective disorder (BAD)






12. This agent regenerates active cholinesterase and is a chemical antagonist used to treat organophosphate exposure






13. MOA of class III antiarrhythmics






14. Irreversible - nonselective COX inhibitor






15. Antidote useful for some drug induced Torsade de pointes






16. Vascular effects of metformin






17. Clinical uses of these agents include treatment of HTN - angina - arrhythmias - chronic CHF - and selected post MI patients






18. These agents are used as antitussive






19. Atropine fever is the most dangerous effect and can be lethal in this population group






20. Antipsychotic having the strongest autonomic effects






21. H1 blocker that is also a serotonin antagonist






22. This is combined with L- dopa - inhibits DOPA decarboxylase (active only peripherally) which allows lower effective doses of L- dopa and allows for fewer SE's (GI distress - postural hypotension - and dyskinesias)






23. Drug elimination with a constant amount metabolized regardless of drug concentration






24. Initial DMARD of choice for patients with RA






25. Partial opioid agonist - considered a strong analgesic - has a long duration of action and is resistant to naloxone reversal






26. Antidote used for opioid toxicity






27. Indirect - Acting ACh Agonist - alcohol - short DOA and used in diagnosis of myasthenia gravis






28. Antidepressant having stimulant effects similar to SSRI's and can increase blood pressure






29. SE of AGI's






30. Treatment of motion sickness






31. Reason ergot alkaloids are contraindicated in pregnancy






32. Lacrimation - rhinorrhea - yawning - sweating - weakness - gooseflesh - nausea - and vomiting - tremor - muscle jerks - and hyperpnea are signs of this syndrome






33. Heterocyclic antidepressants least likely to affect sexual performance - used for management of nicotine withdrawal - SE's include dizziness - dry mouth - aggravation of psychosis - and seizures






34. PTU (propylthiouracil) MOA






35. Antidote to reverse actions of heparin






36. Very rapid acting insulin - having fastest onset and shortest duration of action






37. The most toxic organophosphate






38. Term for a high margin of safety






39. Main route of metabolism for benzodiazepines






40. Antibiotic causing red - man syndrome - and prevention






41. Agent having no effect on D2 receptors - blocks D4 - reserved for resistant schizophrenia - and can cause fatal agranulocytosis






42. Drug notorious for causing pseudomembranous colitis






43. Anti - androgen used for prostate cancer






44. Converts asparagine to aspartate and ammonia - denies cancer cells of essential AA (asparagine)






45. B- blockers that are more cardioselective






46. Meningitis prophylaxis in exposed patients






47. Short acting Beta 2 agonists that is drug of choice in treatment of acute asthma but not recommended for prophylaxis






48. Antiglaucoma organophosphate






49. Weak opioid agonist - poor analgesic - its overdose can cause severe toxicity including respiratory depression - circulatory collapse - pulmonary edema - and seizures






50. MOA of class I A (eg. Procainamide) - class IB (eg. Lidocaine) - and class IC (eg. Flecainide) antiarrhythmics