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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Neurologic SE of benzodiazepines






2. Radio contrast media that inhibits the conversion of T4 to T3






3. The fraction of administered dose of a drug that reaches systemic circulation






4. Antidote to reverse actions of heparin






5. Treatment of resistant pseudomembranous colitis






6. Selective alpha agonists that decreases aqueous secretion






7. Agent that is the antidote for methanol overdose






8. MOA of quinolones






9. Inhibits conversion of cholesterol to pregnenolone therefore inhibiting corticosteroid synthesis






10. Anti - seizure drugs used also for bipolar affective disorder (BAD)






11. Approved for use in severe pulmonary HTN






12. MOA of class IV antiarrhythmics






13. Structurally related to acetylcholine - used to produce muscle paralysis in order to facilitate surgery or artifical ventilation. Full doses lead to respiratory paralysis and require ventilation






14. Readily detected markers that may assist in diagnosis of the cause of a drug overdose include






15. Antidote to reverse actions of warfarin






16. MOA of both generations






17. MOA of erythromycin






18. SE for ganciclovir






19. Used to treat patients exposed to insecticides such as parathion






20. MOA of Leflunomide (newer agent)






21. PTU (propylthiouracil) MOA






22. Thrombolytic that can cause allergic reaction






23. Drug of choice for leprosy






24. These LA's have surface activity






25. Agents having higher sedation and antimuscarinic effects than other TCA's






26. Agent used for closure of patent ductus arteriosus






27. Antidepressant associated with seizures and cardiotoxicity






28. Agent decreases the excitatory actions of cholinergic neurons. May improve tremor and rigidity but have LITTLE effect on bradykinesia. Atropine - like side effects






29. Agents acting in the CNS or in the skeletal muscle - used to reduce abnormally elevated tone caused by neurologic or muscle end plate disease






30. Route of administration of warfarin






31. SE of Amiodarone






32. SE of OCs






33. B- blockers that are more cardioselective






34. MOA of AGI's






35. Site of action for zaleplon and zolpidem






36. 2nd generation antihistamines






37. Usual time needed for full effect of antidepressant therapy






38. Anti - viral with a dose limiting toxicity of pancreatitis






39. Antidote for acetaminophen toxicity






40. The ratio of the rate of elimination of a drug to its plasma concentration






41. Important in synthesis of glucose to glycogen in the liver






42. Class of drugs with ability to decrease the maximal response to an agonist






43. 'Date rape drug'






44. Type of kinetics when a constant percentage of substrate is metabolized per unit time






45. Drugs decrease intestinal absorption of cholesterol






46. Used intravenously for acute arrhythmias during surgery






47. Anti - androgen used for hirsutism in females






48. Drug used in Chagas disease






49. Incidence of hyoglycemia with metformin






50. Cholinomimetics that increase outflow - open trabecular meshwork - and cause ciliary muscle contraction







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