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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Chronic high dose abuse of nicotine leads to






2. Non - benzodiazepine used as an anxiolytic






3. Antidepressant which is inhibitor of CYP450 enzymes and may be associated with hepatic failure






4. These agents are used as antidiarrheal






5. MOA of nateglinide






6. MOA of both generations






7. Anti - androgen used for hirsutism in females






8. MOA of local anesthetics (LA's)






9. Class of antibiotics that have 10% cross sensitivity with penicillins






10. Aspirin reduces mortality in unstable angina by






11. All opioids except this agent (which has a muscarinic blocking action) cause pupillary constriction






12. SE of acetaminophen






13. Weak opioid agonist - poor analgesic - its overdose can cause severe toxicity including respiratory depression - circulatory collapse - pulmonary edema - and seizures






14. Class II antiarrhythmics are






15. Amount of drug necessary to elicit a biologic effect; refers to the drug's strength






16. DOC for malignant hyperthermia that may be caused by use of halogenated anesthetics






17. Side effect of sotalol






18. Toxicity of these agents include bradycardia - AV blockade - exacerbation of acute CHF; signs of hypoglycemia may be masked (tachycardia - tremor - and anxiety)






19. Drug ofter used in combination with TNF - alpha inhitors for RA






20. May protect against doxorubicin toxicity by scavenging free radicals






21. Technique used to diagnose perianal itching - and the drug used to treat it






22. Agent more frequently associated with extrapyramidal side effects that can be treated with benzodiazepine - diphenhydramine or muscarinic blocker






23. SE for Lamotrigine






24. Clinical use for H2 blockers






25. Major drug interaction with Quinidine






26. Important in synthesis of glucose to glycogen in the liver






27. For rebound HTN from rapid clonidine withdrawal






28. Oral contraceptive available in a transdermal patch






29. Drug that causes contraction of the uterus






30. Newer alpha 2 agonist (apraclonidine and brimonidine) treat glaucoma by acting to






31. Opioid antagonist that is given orally in alcohol dependency programs






32. Cheap wide spectrum antibiotic DOC for otitis media






33. Used intranasally and decreases bone resorption






34. MOA of Leflunomide (newer agent)






35. SE for ticlopidine






36. Lactam that can be used in PCN allergic patients






37. SE of procainamide






38. The most important sign of withdrawal syndrome






39. Antivirals associated with neutropenia






40. Four main actions of NSAIDS






41. Opioid that can be given PO - by epidural - and IV - which helps to relieve the dyspnea of pulmonary edema






42. This may enhance activity of local anesthetics






43. Class of drugs that reversibly inhibit COX






44. Only direct acting agent that is very lipid soluble and used in glaucoma






45. Combined alpha and beta blocking agents that may have application in treatment of CHF






46. Almost all local anesthetics have this property and sometimes require the administration of vasoconstrictors (ex. Epinephrine) to prolong activity






47. Used for SIADH






48. Long acting sympathomimetic - sometimes used to improve urinary continence in children and elderly with enuresis






49. Median toxic dose required for a toxic effect in 50% of the population






50. Newer estrogen receptor antagonist used in advanced breast cancer