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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. All antidepressants have roughly the same efficacy in treating depression - agents are chosen based on these criterion






2. Agent with long duration of action and is most likely to cause histamine release






3. Commonly abused LA which has cardiovascular toxicity including severe hypertension with cerebral hemorrhage - cardiac arrhythmias - and myocardial infarction






4. SE of acetaminophen






5. Newer alpha 2 agonist (apraclonidine and brimonidine) treat glaucoma by acting to






6. Aminoglycoside that is least ototoxic






7. Most inhaled anesthetics SE






8. Selective Alpha 2 blocker used for impotence (controversial effectiveness)






9. Anti - seizure medication also used in the prevention of migraines






10. SE of amrinone






11. Anti - thyroid drugs






12. MOA of quinolones






13. MOA of repaglinide






14. MOA of aspirin






15. SE of niacin






16. Antidote used for heparin overdose






17. Class III antiarrhythmic that exhibits properties of all 4 classes






18. These drugs strongly potentiate and prolong effect of neuromuscular blockade (NMB)






19. MOA action of cromolyn






20. Partial opioid agonist - considered a strong analgesic - has a long duration of action and is resistant to naloxone reversal






21. Inhaled anesthetic - less likely to lower blood pressure than other agents - and has the smallest effect on respiration






22. Antidepressant also used for sleep that causes priapism






23. Thyroxine dose may need to be increased in hypothyroid patient during pregnancy because






24. Only direct acting agent that is very lipid soluble and used in glaucoma






25. The most toxic organophosphate






26. Common mechanism by which overdose result in death






27. Fluoride released by metabolism of this inhaled anesthetic may cause renal insufficiency






28. Inhaled anesthetic that may sensitize the myocardium to arrhythmogenic effects of catecholamines and has produced hepatitis






29. Neurologic SE of benzodiazepines






30. Drug that inhibits alcohol dehydrogenase and is used in ethylene glycol exposure






31. Common SE of spironolactone






32. Anticancer drug also used in RA - produces acrolein in urine that leads to hemorrhagic cystitis






33. The fraction of administered dose of a drug that reaches systemic circulation






34. SE of beta blockers






35. Agent that inhibits alcohol dyhydrogenase and its clinical use






36. Clinical response that may fluctuate in tx of Parkinson's dx

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37. Non - benzodiazepine used for sleep






38. Agent that is teratogen and causes a fetal syndrome






39. Uses of bisphosphonates

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40. Drugs available in combination with metformin






41. What do alpha cells in the pancreas produce?






42. Vascular effects of metformin






43. A hormone whose MOA utilizes transmembrane receptors






44. Anti - viral agents associated with Stephen Johnson syndrome






45. Carbonic anhydrase inhibitor






46. SSRI with long T1/2 and can be administered once weekly for maintenance - not acute tx






47. Captopril and enalapril (- OPRIL ending) are






48. W/D from this drug causes anxiety and mental discomfort






49. Concentration in the plasma times (clearance divided by bioavailability)






50. Thiazolidinediones