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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. SE seen only in men with administration of ketoconazole






2. Toxicities include nephrotoxicity and ototoxicity - leading to a severe interaction with aminoglycosides






3. COX 2 inhibitors should be used cautiously in pts with






4. Beta 1 agonist toxicity






5. Vitamin K dependent anticoagulant






6. Inducers of Cytochrome P450 (CYP450)






7. This agent cause increased aqueous outflow






8. Nonselective alpha - blocking drug - long acting and irreversible - and used to treat pheochromocytoma. Blocks 5- HT - so occasionaly used for carcinoid tumor. Blocks H1 and used in mastocytosis






9. This agent regenerates active cholinesterase and is a chemical antagonist used to treat organophosphate exposure






10. DOC to treat chemo - induced nausea and vomiting






11. Antidote used for cyanide poisoning






12. Major route of elimination for Lithium






13. Drug is used with testosterone for male fertility






14. Antidote to reverse actions of warfarin






15. Barbiturates decrease the effectiveness of many other drugs via this pharmacokinetics property






16. NSAID also available as an ophthalmic preparation






17. Used especially in postmenopausal women - dosage should be 1500 mg






18. Agent effective in physiologic and essential tremor






19. This may enhance activity of local anesthetics






20. This is combined with L- dopa - inhibits DOPA decarboxylase (active only peripherally) which allows lower effective doses of L- dopa and allows for fewer SE's (GI distress - postural hypotension - and dyskinesias)






21. Side effects seen with tricyclic antidepressants






22. Only phenothiazine not exerting antiemetic effects - can cause visual impairment due to retinal deposits - and high doses have been associated with ventricular arrhythmias






23. Strength of interaction between drug and its receptor






24. Drug that causes gray baby syndrome and aplastic anemia






25. Anti - seizure agent that exhibits non - linear metabolism - highly protein bound - causes fetal hydantoin syndrome - and stimulates hepatic metabolism






26. SE of amrinone






27. Digoxin toxicity can be precipitated by






28. NSAID used in gout






29. Bleomycin+vinblastine+etoposide+cisplatin produce almost a 100% response when all agents are used for this neoplasm






30. Drug that inhibits alcohol dehydrogenase and is used in ethylene glycol exposure






31. PTU (propylthiouracil) MOA






32. Proteins that prevent action of tumor necrosis factor alpha (TNF- alpha)






33. Agent used neutropenia especially after chemotherapy






34. Used intranasally and decreases bone resorption






35. Inhibits conversion of cholesterol to pregnenolone therefore inhibiting corticosteroid synthesis






36. Carbamazepine may cause






37. Amount of drug necessary to elicit a biologic effect; refers to the drug's strength






38. Drug that selectively inhibits COX 2






39. H1 blocker that is also a serotonin antagonist






40. Rapid acting insulins that do not self - aggregate






41. Non - benzodiazepine used as an anxiolytic






42. Site of action of loop diuretics






43. Treatment of patients with prior episodes of thrombocytopenia after a cycle of cancer chemotherapy






44. Anti - seizure drugs used as alternative drugs for mood stabilization






45. Sedation is a common side effect of these drugs - they lower seizure threshold - uses include BAD - acute panic attacks - phobias - enuresis - and chronic pain and their overdose can be deadly






46. Anemia caused by trimethoprim






47. Agent with zero - order kinetics






48. SE of minoxidil






49. The selective agents loose their selectivity at






50. Example of three antidepressants that are indicated for obsessive compulsive disorder