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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. MOA of quinolones






2. Class of antibiotics that have 10% cross sensitivity with penicillins






3. Slightly increased risk of breast cancer - endometrial cancer - heart disease (questionable) - has beneficial effects on bone loss






4. Antiestrogen drugs used for fertility and breast cancer respectively






5. Commonly abused LA which has cardiovascular toxicity including severe hypertension with cerebral hemorrhage - cardiac arrhythmias - and myocardial infarction






6. Agents that block L- type calcium channel






7. Common SE of tamoxifen and raloxifene






8. 2nd generation antihistamines






9. Peptide drug used to treat CHF






10. Captopril and enalapril (- OPRIL ending) are






11. Agent used for neurological deficits in megaloblastic anemia






12. Antidote for digoxin toxicity






13. Prostaglandins that cause abortions






14. Bisphosphonates that cannot be used on continuous basis because it caused osteomalacia






15. Biguanide






16. Toxicity of these agents include bradycardia - AV blockade - exacerbation of acute CHF; signs of hypoglycemia may be masked (tachycardia - tremor - and anxiety)






17. The most frequent cause of acute deaths in cholinesterase inhibitor toxicity






18. Where are beta cells found in the pancreas?






19. Antidote useful for some drug induced Torsade de pointes






20. Agent that is the antidote for methanol overdose






21. Selective estrogen receptor modulator (SERM) used for prevention of osteoporosis and prophylaxis in women with risk factors for breast cancer






22. Agent for pernicious anemia






23. Antipsychotic having the weakest autonomic effects






24. Dose may need to be increased during pregnancy or with Ocs due to increased TBG in plasma






25. Benzodiazepine used for anxiety






26. MOA of thrombolytics






27. Most widely used thyroid drugs such as Synthroid and Levoxyl contain






28. Endogenous insulin contains






29. COX 2 inhibitors may have reduced risk of






30. MOA of thiazide diuretics






31. Antivirals associated with neutropenia






32. Tubocurarine is the prototype - pancuronium - atracurium - vecuronium are newer short acting agent - produce competitive block at end plate nicotinic receptor - causing flaccid paralysis






33. Agent used in the treatment of alcoholism - if alcohol is consumed concurrently - acetaldehyde builds up and results in nausea - headache - flushing - and hypotension






34. Local anesthetic with vasoconstrictive property - favored for head - neck - and pharyngeal surgery






35. Anti - psychotic not shown to cause tardive dyskinesia






36. Class of drugs with ability to decrease the maximal response to an agonist






37. Agent used in acutely decompensated CHF resembling natriuretic peptide






38. Selective Alpha -1A blocker - used for BPH - but with little effect on HTN






39. TCA used in obsessive compulsive disorder (OCD) - most significant of TCA's for risk of seizure - weight gain - and neuropsychiatric signs and symptoms






40. Strength of interaction between drug and its receptor






41. Example of three antidepressants that are indicated for obsessive compulsive disorder






42. Most common SE of fibrates






43. Anti - seizure drugs used also for bipolar affective disorder (BAD)






44. Cholestyramine and colestipol are






45. MOA of class III antiarrhythmics






46. NSAID available orally - IM and ophthalmically






47. Three C's associated with TCA toxicity






48. Toxicity of organophosphate:






49. Non - selective Alpha1blockers use to treat pheochromocytoma






50. These agents are used as antidiarrheal