SUBJECTS
|
BROWSE
|
CAREER CENTER
|
POPULAR
|
JOIN
|
LOGIN
Business Skills
|
Soft Skills
|
Basic Literacy
|
Certifications
About
|
Help
|
Privacy
|
Terms
|
Email
Search
Test your basic knowledge |
USMLE/COMLEX Step 1 Pharmacology One Liners
Start Test
Study First
Subjects
:
health-sciences
,
usmle-step-1
,
comlex
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Plasma concentration of a drug at a given time
Cp
Inhibits phosphodiesterase -5 - enhancing effects of nitric oxide - activated increases in cGMP
Cimetidine - ketoconazole - erythromycin - isoniazid and grapefruit
Nondepolarizing Neuromuscular Blockers
2. Epinephrine is often mixed with a local anesthetic to
N- acetylcysteine
Excessive hypotension and kidney failure
Penicillamine
Reduce the loss from area of injection
3. MOA action of cromolyn
Mast cell stabilizer
Acid reflux disease - duodenal ulcer and peptic ulcer disease
Paclitaxel (taxol)
Salmeterol
4. One depolarizing blocker that causes continuous depolarization and results in muscle relaxation and paralysis - causes muscle pain postoperatively and myoglobinuria may occur
Sedation
Megaloblastic anemia
Valproic acid
Succinylcholine
5. '5HT-1d agonist used for migraine headaches '
Propofol
Sumatriptan - naratriptan - and rizatriptan
Barbiturates - phenytoin - carbamazepine - and rifampin
Aspirin - Nitrates - CCB - and Beta blockers
6. This beta blocker lacks local anesthetic activity (a property which decreases protective reflexes and increases the risk of corneal ulceration) and used in treating glaucoma
CNS toxicity
Sedation
Amphetamines
Timolol
7. Used for hairy cell leukemia; it stimulates NK cells
6- mercaptopurine (6- MP)
Ketamine
Interferon alpha
Midazolam
8. Drug of choice for leprosy
Block cell wall synthesis by inhibiting peptidoglycan cross - linkage
Methotrexate
Dapsone - rifampin and clofazimine combination
Clonidine - and methyldopa
9. Antidepressants with no effect on BP - no sedation
Decreases hepatic glucose production and intestinal glucose absorption; increase insulin sensitivity
Oxytocin
SSRIs
Timolol
10. Carbonic anhydrase inhibitor
Acetazolamide
Ethanol or fomepizole
Aspirin
Loading dose (Cp*(Vd/F))
11. Beta 1 agonists used in acute CHF
Zafirlukast and montelukast
Neuroleptanesthesia
Dobutamine and dopamine
Raloxifene
12. Treatment with cancer chemotherapy at high doses every 3-4 weeks - too toxic to be used continuously
Pulse therapy
Dapsone - rifampin and clofazimine combination
Administration of Vit. B6 (pyridoxine)
Indomethacin
13. Long acting sympathomimetic - sometimes used to improve urinary continence in children and elderly with enuresis
Ethanol - fomepizole
Pulmonary embolism and DVT
Pulse therapy
Ephedrine
14. Presynaptic Alpha 2 agonist used in HTN - and acts centrally
Clonidine - and methyldopa
Aspirin
NO - chloroform - and diethyl ether
Cyclophosphamide
15. Another pneumonic for anticholinergic toxicity
Warning
: Invalid argument supplied for foreach() in
/var/www/html/basicversity.com/show_quiz.php
on line
183
16. Selective Alpha 1 blocker used for hypertension - BPH - may cause first dose orthostatic hypotension
SSRI's - bupropion - and venlafaxine
Physostigmine
Cholinesterase inhibitors
Prazosin - terazosin - doxazosin
17. Reduce transient hyper GI motility
Gingival hyperplasia - nystagmus - diplopia and ataxia
Dicyclomine - methscopolamine
Fluoxetine
Neutropenia and agranulocytosis
18. Tolerance to all effects of opioid agonists can develop except
Diazepam
Efficacy
Indomethacin
Miosis and constipation
19. Except for these agents all SSRI have significant inhibition of CytP450 enzymes
Ethanol - fomepizole
Zero order kinetics
Bioavailability (F)
Citalopram and its metabolite escitalopram
20. Technique used to diagnose perianal itching - and the drug used to treat it
Nephro and ototoxicity
Lispro (Humalog) - aspart - glulisine
Aplastic anemia and renal toxicity
Scotch tape technique and mebendazole
21. Thiazolidinediones
Pioglitazone - Rosiglitazone - Troglitazone (withdrawn/d from market)
Dimercaprol - EDTA
Orthostatic hypotension (especially with first dose) and reflex tachycardia
Rhabdomyolysis and Hepatotoxicity
22. This may antagonize activity of local anesthetics
Seizures
Atracurium
Prolonged half - life - up to six weeks
Hypercalcemia
23. Potassium sparing diuretics inhibit
Calcitonin (salmon prep)
Atropine - homatropine - C1208 tropicamide
Na+/K+ exchange
Bromocriptine
24. Rapid acting insulins that do not self - aggregate
Tolerance
Paclitaxel (taxol)
GLUT 4
lispro insulin - aspart insulin - glulisine insulin
25. Fibrates are contraindicated in
Excessive CNS stimulation (seizures)
Diazepam
Fomepizole
Pregnancy
26. Benzodiazepine that is used for anesthesia
Phentolamine
Midazolam
Sinus tachycardia and serious arrhythmias
'dry as a bone - red as a beet - mad as a hatter - hot as a hare - blind as a bat'
27. Antidote used for acetaminophen (APAP) toxicity
N- acetylcysteine (Mucomyst)
Ephedrine
Pramipexole and ropinirole
Nitroglycerin sublingual tablets
28. Only phenothiazine not exerting antiemetic effects - can cause visual impairment due to retinal deposits - and high doses have been associated with ventricular arrhythmias
Epinephrine
Clomipramine
Organic nitrites
Thioridazine
29. Weak opioid agonist - poor analgesic - its overdose can cause severe toxicity including respiratory depression - circulatory collapse - pulmonary edema - and seizures
Additive CNS depression
Acetazolamide
Propoxyphene
Dopamine
30. Commonly abused LA which has cardiovascular toxicity including severe hypertension with cerebral hemorrhage - cardiac arrhythmias - and myocardial infarction
Cocaine
Phentolamine
Pulmonary embolism and DVT
Probenecid and sulfinpyrazone
31. SE of imipenem
Seizures
Alprazolam
Valproic acid - carbamazepine - phenytoin and gabapentin
Psychotic state - overdose causes agitation - restlessness - tachycardia - hyperthermia - hyperreflexia - and seizures
32. Diuretic used for mountain sickness and glaucoma
Skeletal muscle tremor - tachycardia
Na+/K+ exchange
Acetazolamide
Somatostatin
33. Newer estrogen receptor antagonist used in advanced breast cancer
Valproic acid - carbamazepine - phenytoin and gabapentin
Maintenance dose (Cp*(CL/F))
Toremifene (Fareston)
Minoxidil
34. This is the drug of choice for anaphylactic shock
Activattion on an inward K+ current and inhibition of Ca++ current resulting in marked hyperpolarization
Terbutaline
Epinephrine
Anti - inflammatory - analgesia - antipyretic and antiplatelet activity
35. SE of long term (>5 days) corticosteroid therapy and remedy
Dimercaprol - EDTA
Adrenal suppression and weaning slowly - respectively
Amitriptyline
Carbenicillin - piperacillin and ticarcillin
36. Anti - Parkinson's drug which increases intraocular pressure and is contraindicated in closed angle glaucoma
Levodopa
Neostigmine
Islets of Langerhans
Hyperuricemia - hypokalemia and ototoxicity
37. Endogenous insulin contains
Bone marrow and teeth discoloration for children under 8 years of age
Nephrotoxicity
Normal C- peptide
Nausea
38. Reason fluoroquinolones are contraindicated in children and pregnancy
Cartilage damage
Valproic acid - carbamazepine - phenytoin and gabapentin
Testicular cancer
Kidneys
39. Antidepressant with MOA as alpha 2 antagonist - has effects on both 5- HT and NE - blocks histamine receptors - and is sedating
Ceftriaxone
Older antipsychotic agents - D2 receptors
Beta - blockers such as propranolol
Mirtazapine
40. MOA of erythromycin
Bethanechol
Inhibition of protein synthesis at the 50s subunit of ribosome
GABA- related targets
Glucagon
41. MOA of neuroleptics
Dopamine blockade
Thioridazine
Bradykinin
Hydration and mercaptoethanesulfonate (MESNA)
42. Non ergot agents used as first - line therapy in the initial management of Parkinson's
Neuroleptanesthesia
Depression of medullary and cardiovascular centers
Pramipexole and ropinirole
Minocycline
43. Common side effect of hypnotic agents
Sedation
Work at early distal convoluted tubule
Streptomycin
Heroin - morphine - oxycodone - meperidine and fentanyl
44. Antidote used for heparin overdose
CNS depressants
Epinephrine
Protamine
Hepatotoxicity
45. Initial DMARD of choice for patients with RA
Reduce the loss from area of injection
REM is decreased
Methotrexate
Peripheral neuropathy (also excessive alcohol use is associated with HTN - anemia - and MI)
46. Cephalosporins able to cross the BBB
Amitriptyline
Penicillamine
Inhibits phosphodiesterase -5 - enhancing effects of nitric oxide - activated increases in cGMP
Cefuroxime (2nd) generation - Ceftazidime - Ceftriaxone
47. MOA of sulfonamides
Decreased micro and macro vascular disease
Haloperidol
Inhibit dihydropteroate synthase
Increases concentration of Digoxin
48. Reduced seizure threshold
Low - potency typical antipsychotics and clozapine
Point mutation
Nitrous oxide
Aminocaproic acid
49. Mast cells to reduce release of hisamine and inflammatory mediators
Cocaine
GFR
Epinephrine
Acid reflux disease - duodenal ulcer and peptic ulcer disease
50. Antipsychotic used in the treatment of psychiatric symptoms in patients with dementia
Older antipsychotics
Sinus tachycardia and serious arrhythmias
lispro insulin - aspart insulin - glulisine insulin
Risperidone
Sorry!:) No result found.
Can you answer 50 questions in 15 minutes?
Let me suggest you:
Browse all subjects
Browse all tests
Most popular tests
Major Subjects
Tests & Exams
AP
CLEP
DSST
GRE
SAT
GMAT
Certifications
CISSP go to https://www.isc2.org/
PMP
ITIL
RHCE
MCTS
More...
IT Skills
Android Programming
Data Modeling
Objective C Programming
Basic Python Programming
Adobe Illustrator
More...
Business Skills
Advertising Techniques
Business Accounting Basics
Business Strategy
Human Resource Management
Marketing Basics
More...
Soft Skills
Body Language
People Skills
Public Speaking
Persuasion
Job Hunting And Resumes
More...
Vocabulary
GRE Vocab
SAT Vocab
TOEFL Essential Vocab
Basic English Words For All
Global Words You Should Know
Business English
More...
Languages
AP German Vocab
AP Latin Vocab
SAT Subject Test: French
Italian Survival
Norwegian Survival
More...
Engineering
Audio Engineering
Computer Science Engineering
Aerospace Engineering
Chemical Engineering
Structural Engineering
More...
Health Sciences
Basic Nursing Skills
Health Science Language Fundamentals
Veterinary Technology Medical Language
Cardiology
Clinical Surgery
More...
English
Grammar Fundamentals
Literary And Rhetorical Vocab
Elements Of Style Vocab
Introduction To English Major
Complete Advanced Sentences
Literature
Homonyms
More...
Math
Algebra Formulas
Basic Arithmetic: Measurements
Metric Conversions
Geometric Properties
Important Math Facts
Number Sense Vocab
Business Math
More...
Other Major Subjects
Science
Economics
History
Law
Performing-arts
Cooking
Logic & Reasoning
Trivia
Browse all subjects
Browse all tests
Most popular tests