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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Diuretics work in CHF by






2. MOA of Cardiac glycosides (eg. digoxin)






3. Antidote for tissue plasminogen activator (t - PA) - streptokinase






4. GHRH analog used as diagnostic agent






5. MOA for Ethosuximide






6. Treatment for opioid addiction






7. Anti - psychotic not shown to cause tardive dyskinesia






8. Mineralocorticoids






9. MOA of metformin






10. MOA of sulfonamides






11. Arterial vasodilator that works by opening K+ channels






12. Cystitis - postoperative bladder spasms - or incontinence






13. Somatotropin (GH) analog used in GH deficiency (dwarfism)






14. MOA of drug or foods (grapefruit juice) that increase statin effect






15. MOA of nystatin






16. Agents having active metabolites - long half lives - and a high incidence of adverse effects






17. Thiazolidinediones






18. ADH agonist used for pituitary diabetes insipidus






19. SE of AGI's






20. MOA of class III antiarrhythmics






21. Benzodiazepine that has efficacy against absence seizures and in anxiety states - such as agoraphobia






22. Antiarrhythmic that exhibits Class II and III properties






23. Dose may need to be increased during pregnancy or with Ocs due to increased TBG in plasma






24. Somatostatin (SRIF) analog used for acromegaly - carcinoid - glucagonoma and other GH producing pituitary tumors






25. Agents used in Tourette's dx






26. Digoxin toxicity can be precipitated by






27. Antipsychotics that reduce positive symptoms only






28. Anti - progesterone used as abortifacient






29. This is the drug of choice for anaphylactic shock






30. Reason benzos are used cautiously in pregnancy






31. Warfarin is contraindicated in






32. Most widely used thyroid drugs such as Synthroid and Levoxyl contain






33. What do beta cells in the pancreas produce?






34. Produces disulfiram - like reaction with ethanol






35. SSRI with long T1/2 and can be administered once weekly for maintenance - not acute tx






36. Technique used to diagnose perianal itching - and the drug used to treat it






37. Tolerance to all effects of opioid agonists can develop except






38. Aspirin reduces mortality in unstable angina by






39. Reversal of blockade by neuromuscular blockers






40. Ability to produce less than 100% of the response






41. DOC for malignant hyperthermia that may be caused by use of halogenated anesthetics






42. Antidote used for methanol and ethylene glycol






43. Newer NSAID that selectively inhibits COX-2






44. W/D from this drug causes anxiety and mental discomfort






45. Agent used in drug therapy of Parkinson's instead of Dopamine which has low bioavailability and does not cross the BBB






46. Agents that inhibit acetaldehyde dehydrogenase






47. Microtubule inhibitor that causes peripheral neuropathy - foot drop (eg. ataxia) - and 'pins and needles' sensation






48. This produces 'dissociative anesthesia' - is a cardiovascular stimulant which may increases intracranial pressure - and hallucinations occur during recovery






49. Example of three antidepressants that are indicated for obsessive compulsive disorder






50. Commonly abused LA which has cardiovascular toxicity including severe hypertension with cerebral hemorrhage - cardiac arrhythmias - and myocardial infarction