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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Cardioselective Beta 1- blockers






2. Allopurinol treats chronic gout by decreasing uric acid production by inhibiting






3. Pneumonic for 3 zones of adrenal cortex






4. Anti - emetics used in association with anti - cancer drugs that are 5- HT3 (serotonin receptor subtype ) antagonists






5. Antidepressant with MOA as alpha 2 antagonist - has effects on both 5- HT and NE - blocks histamine receptors - and is sedating






6. Inversely related to potency of anesthetics






7. Agent that is a partial agonist for the 5- HT1A receptor






8. Selective Alpha 1 blocker used for hypertension - BPH - may cause first dose orthostatic hypotension






9. Beta blockers work in CHF by






10. Time it takes for amount of drug to fall to half of its value; this is a constant in first order kinetics (majority of drugs)






11. Use of this opioid with MAOI can lead to hyperpyrexic coma - and with SSRI's can lead to serotonin syndrome






12. Ergot alkaloid used as an illicit drug






13. SE of HMG COA reductase inhibitors






14. Antidepressant also used for sleep that causes priapism






15. SE of salicylates






16. SE of Aspirin






17. When the rate of drug input equals the rate of drug elimination






18. Antidote used in poisonings: copper (Wilson's disease) - lead - mercury - and arsenic






19. Longer acting benzodiazepines used in the management of withdrawal states of alcohol and other drugs






20. Common SE of spironolactone






21. Antidote used for digitalis toxicity






22. Antidepressant associated with neuroleptic malignant syndrome






23. Prototype antagonist of H1 and H2 receptors






24. DOC for paroxysmal supraventricular tachycardia; has high efficacy and short duration of action






25. Agents that inhibit acetaldehyde dehydrogenase






26. Treatment of withdrawal syndrome involves






27. Approved for use in severe pulmonary HTN






28. PTU (propylthiouracil) MOA






29. Antifungal agent used for inhibition of all gonadal and adrenal steroids






30. MOA of nitrates






31. Anti - psychotics available in depot preparation






32. Dopamine (DA) agonist (for Parkinson's disease) - used also for hyperprolactinemia






33. Antipsychotic used in the treatment of psychiatric symptoms in patients with dementia






34. Difference between COX 1 and COX 2






35. Most common side effect of 1st generation antihistamines






36. Antidote used for benzodiazepine toxicity






37. Chelating agent used in acute iron toxicity






38. Inhibitor of lipoxygenase






39. Beta 2 agonist used to suppress premature labor - but cardiac stimulatory effects may be hazardous to mother and fetus






40. Neurotransmitters affected by the action of antidepressants






41. Antidote used for acetaminophen (APAP) toxicity






42. Anti - rheumatic agent also used for ulcerative colitis






43. Common toxicities of cisplatin






44. DOC for paroxysmal supraventricular tachycardia (PSVT)






45. MOA of loop diuretics






46. Tolerance to all effects of opioid agonists can develop except






47. Major drug interaction with Quinidine






48. Anti - seizure drugs used also for bipolar affective disorder (BAD)






49. Distribution of histamine receptors H1 - H2 - and H3






50. Common mechanism by which overdose result in death






Can you answer 50 questions in 15 minutes?



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