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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Side effects occuring in antipsychotics that block dopamine






2. Barbiturate used for the induction of anesthesia






3. Antidepressant associated with seizures and cardiotoxicity






4. Agent having no effect on D2 receptors - blocks D4 - reserved for resistant schizophrenia - and can cause fatal agranulocytosis






5. Drug that inhibits alcohol dehydrogenase and is used in ethylene glycol exposure






6. Contraindications to use of atropine






7. Short acting Beta 2 agonists that is drug of choice in treatment of acute asthma but not recommended for prophylaxis






8. Example of three antidepressants that are indicated for obsessive compulsive disorder






9. Digoxin toxicity can be precipitated by






10. Scabicide organophosphate






11. SE of procainamide






12. Amino acid derivative - active as an insulin secretagogue






13. Irreversible condition resulting from the use of antipsychotics - reserpine at high doses - and MPTP (by- product of illicit meperidine analog)






14. Agent used for closure of patent ductus arteriosus






15. Antipsychotics that reduce positive symptoms only






16. Dopamine (DA) agonist (for Parkinson's disease) - used also for hyperprolactinemia






17. The most toxic organophosphate






18. Agent to treat torsades de pointes






19. Term for a narrow margin of safety






20. These Beta blockers decrease aqueous secretion






21. GnRH agonist used for infertility or different types of CA depending on pulsatile or steady usage respectively






22. DOC for digoxin induced arrhythmias






23. Selective alpha agonists that decreases aqueous secretion






24. SelectiveB1 Receptor blockers that may be useful in treating patients even though they have asthma






25. Common side effect of Rifampin






26. Opioid antagonist that is given IV and had short DOA






27. Hyperglycemic agent that increases cAMP and results in glycogenolysis - gluconeogenesis - reverses hypoglycemia - also used to reverse severe beta - blocker overdose and smooth muscle relaxation






28. Period of time of therapy after which GC therapy will need to be tapered






29. Drug is used with testosterone for male fertility






30. Agents for reduction of postpartum bleeding






31. Antidepressant associated with neuroleptic malignant syndrome






32. Inhibitor of MAO type B which metabolizes dopamine - used adjunct to levodopa or as sole agent in newly diagnosed patients






33. Benzodiazepine with useful relaxant effects in skeletal muscle spasticity of central origin






34. Only member of depolarizing neuromuscular blocker - causes fasciculation during induction and muscle pain after use; has short duration of action






35. Prototypical drug is atropine






36. CCB are DOC for

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37. This diuretic decreases aqueous secretion due to lack of HCO3- ion. Causes drowsiness and paresthesias - alkalinization of the urine may precipitate calcium salts - hypokalemia - acidosis






38. Antipsychotic having the strongest autonomic effects






39. Anti - biotic frequently used for chronic UTI prophylaxis






40. Drug causing depletion of substance P (vasodilator)






41. Antidote used for anticholinergic poisoning






42. Antidote for thrombolytics






43. Side effects seen with tricyclic antidepressants






44. Anti - seizure agent that induces formation of liver drug - metabolism enzymes - is teratogen and can cause craniofacial anomalies and spina bifida






45. Non - selective Beta - blocker also used for migraine prophylaxis






46. Antidote used for acetaminophen (APAP) toxicity






47. Newer atypical antipsychotics that also improve some of the negative symptoms and help acute agitation






48. Drug used in ergot alkaloids overdose - ischemia and gangrene






49. Used for hairy cell leukemia; it stimulates NK cells






50. Sympathetic agent which stimulates heart rate and can dilate vessels in skeletal muscle at low doses