Test your basic knowledge |

USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Beta blockers are used for which type of anginal attack






2. Class III antiarrhythmic that exhibits properties of all 4 classes






3. Drug notorious for causing pseudomembranous colitis






4. DOC for paroxysmal supraventricular tachycardia; has high efficacy and short duration of action






5. Interact with microtubules (but unlike vinca which prevent disassembly of tubules) - it stabilizes tubulin and cells remain frozen in metaphase






6. SE of tPA






7. Diuretics work in CHF by






8. Cephalosporin causes kernicterus in neonates






9. Some cell cycle non - specific drugs






10. Thrombolytics are used for






11. First generation sulfonylurea






12. New class of drugs that works by inhibiting absorption of intestinal cholesterol and can be given concurrently with the Statins






13. Non - benzodiazepine used as an anxiolytic






14. Regimen used for breast cancer






15. Prevention of cyclophosphamide induced hemorrhagic cystitis






16. Concern using lithium






17. Anti - seizure agent that exhibits non - linear metabolism - highly protein bound - causes fetal hydantoin syndrome - and stimulates hepatic metabolism






18. Antidote used for benzodiazepine toxicity






19. Drug used for MRSA






20. Antidote for hyperkalemia






21. Fluoride released by metabolism of this inhaled anesthetic may cause renal insufficiency






22. SE of Amiodarone






23. Non - benzodiazepine used for sleep






24. Selective Alpha 2 blocker used for impotence (controversial effectiveness)






25. This beta blocker is highly lipid soluble and may account for side effects such as nightmares






26. Drug elimination with a constant amount metabolized regardless of drug concentration






27. Constant low dose of estrogen and increasing dose of progestin for 21 days (last 5 days are sugar pills or iron prep)






28. Opioids used in anesthesia






29. Antidote used for digitalis toxicity






30. Amphetamine agents






31. This diuretic decreases aqueous secretion due to lack of HCO3- ion. Causes drowsiness and paresthesias - alkalinization of the urine may precipitate calcium salts - hypokalemia - acidosis






32. Side effects frequently seen with SSRIs






33. Causes bone marrow suppression






34. MAOI should not be administered with SSRI's or potent TCA's due to development of this condition






35. Agent used for acute muscle spasm






36. Irreversible condition resulting from the use of antipsychotics - reserpine at high doses - and MPTP (by- product of illicit meperidine analog)






37. Anti - seizure drugs used also for bipolar affective disorder (BAD)






38. SE for Lamotrigine






39. 3 zones of adrenal cortex and their products






40. Muscarinic antagonist used in asthma






41. MOA action of cromolyn






42. Inhaled anesthetics metabolized by liver enzymes which has a major role in the toxicity of these agents






43. This beta blocker lacks local anesthetic activity (a property which decreases protective reflexes and increases the risk of corneal ulceration) and used in treating glaucoma






44. Can be effective for short term therapy of thyroid storm - but after several weeks of therapy causes an exacerbation of hyperthyroidism






45. Non - steroidal estrogen agonist causes clear cell adenocarcinoma of the vagina in daughters of women who used it during pregnancy






46. DOC for malignant hyperthermia by acting on the sacroplasmic reticulum or skeletal muscle






47. Agents may exacerbate tardive dyskinesias (may be irreversible and there is no treatment)






48. Antipsychotic having the strongest autonomic effects






49. Antivirals associated with neutropenia






50. Usual time needed for full effect of antidepressant therapy