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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Associated with an increased incidence of cataracts in patients treated for glaucoma






2. Most widely used thyroid drugs such as Synthroid and Levoxyl contain






3. These agents are congeners of Amphetamine

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4. This step of metabolism makes a drug more hydrophilic and hence augments elimination






5. This agent cause increased aqueous outflow






6. Non - depolarizing skeletal muscle antagonist that has short duration






7. Target plasma concentration times (volume of distribution divided by bioavailability)






8. Neurologic SE of benzodiazepines






9. Anti - arrhythmics that decrease mortality






10. Major route of elimination for Lithium






11. Important in muscle and adipose tissue for glucose transport across muscles and TG storage by lipoprotein lipase activation






12. Pneumonic for beta receptors






13. Drug that causes contraction of the uterus






14. Biguanide






15. Approved for use in severe pulmonary HTN






16. Non ergot agents used as first - line therapy in the initial management of Parkinson's






17. Antidote used for acetaminophen (APAP) toxicity






18. Major nutritional side effect of bile acid - binding resins






19. This beta blocker is the longest acting






20. Tolerance to all effects of opioid agonists can develop except






21. DOC for Legionnaires' disease






22. Agent having no effect on D2 receptors - blocks D4 - reserved for resistant schizophrenia - and can cause fatal agranulocytosis






23. Agent used neutropenia especially after chemotherapy






24. Class of drugs that may cause cross - sensitivity with thiazide diuretics






25. Anti - Parkinson's drug which increases intraocular pressure and is contraindicated in closed angle glaucoma






26. Anti - microbials that cause hemolysis in G6PD- deficient patients






27. Window between therapeutic effect and toxic effect






28. SE for Lamotrigine






29. Antidepressant with MOA as alpha 2 antagonist - has effects on both 5- HT and NE - blocks histamine receptors - and is sedating






30. Fibrates (gemfibrozil) increase activity of






31. Most dangerous of the currently popular hallucinogenic drugs - OD leads to nystagmus - marked hypertension - and seizures - presence of both horizontal and vertical nystagmus is pathognomonic






32. Type of kinetics when a constant percentage of substrate is metabolized per unit time






33. Agent that is teratogen and causes a fetal syndrome






34. Toxicities include nephrotoxicity and ototoxicity - leading to a severe interaction with aminoglycosides






35. This agent has greater affinity for muscarinic receptors and used for postoperative and neurogenic ileus and urinary retention






36. Sympathetic agent which stimulates heart rate and can dilate vessels in skeletal muscle at low doses






37. NSAID used in gout






38. Agent effective in physiologic and essential tremor






39. Activation of these receptors open K+ ion channels to cause membrane hyperpolarization






40. SE of long term (>5 days) corticosteroid therapy and remedy






41. Longer acting local anesthetics which are less dependent on vasoconstrictors






42. Angiotensin receptor blockers do Not cause






43. Agent that is metabolized to acetaldehyde by alcohol dehydrogenase and microsomal ethanol - oxidizing system (MEOS)






44. SE of colchicine






45. Thrombolytic used for acute MI and ischemic (non hemorrhagic) CVA






46. Digoxin is used in






47. Scabicide organophosphate






48. Agent that inhibits alcohol dyhydrogenase and its clinical use






49. Loops lose and thiazide diuretics retain






50. Agent which stimulates cardiac contractile force more than rate with little effect on total peripheral resistance






Can you answer 50 questions in 15 minutes?



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