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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. MOA of sulfonamides






2. Maximum response achieveable from a drug






3. DOC for paroxysmal supraventricular tachycardia (PSVT)






4. Toxicity of these agents include bradycardia - AV blockade - exacerbation of acute CHF; signs of hypoglycemia may be masked (tachycardia - tremor - and anxiety)






5. Drug used in Chagas disease






6. Beta 2 agonist toxicity






7. Class of anti - arrhythmics that has a pro - arrhythmic effect (CAST trial) - therefore are used as last line agents






8. Used for prevention of postmenopausal osteoporosis in women






9. Anti - seizure drugs used also for pain of neuropathic orgin






10. MOA for benzodiazepines and barbiturates






11. Antidote used for anticholinergic poisoning






12. Agent that is the antidote for methanol overdose






13. Antidote for salicylate intoxication






14. Irreversible - nonselective COX inhibitor






15. Agent used for neurological deficits in megaloblastic anemia






16. Some of SSRIs' therapeutic effects beside depression






17. Major effect of benzodiazepines on sleep at high doses






18. Tubocurarine is the prototype - pancuronium - atracurium - vecuronium are newer short acting agent - produce competitive block at end plate nicotinic receptor - causing flaccid paralysis






19. What do beta cells in the pancreas produce?






20. Antiplatelet drug reserved for patients allergic to aspirin






21. Antidote to benzodiazepine overdose (antagonist that reverses the CNS effects)






22. Well - tolerated and are first - line antidepressants

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23. Class of drugs that reversibly inhibit COX






24. Constant low dose of estrogen and increasing dose of progestin for 21 days (last 5 days are sugar pills or iron prep)






25. Withdrawal from this drug causes lethargy - irritability - and headache






26. SE of long term (>5 days) corticosteroid therapy and remedy






27. Local anesthetic with vasoconstrictive property - favored for head - neck - and pharyngeal surgery






28. Common toxicities of cisplatin






29. These LA's have surface activity






30. Drug notorious for causing pseudomembranous colitis






31. Agents used in Huntington's Disease






32. Long acting sympathomimetic - sometimes used to improve urinary continence in children and elderly with enuresis






33. Drug causing depletion of substance P (vasodilator)






34. Pyrimidine analog that causes 'Thymine - less death' given with leucovorin rescue






35. The most important sign of withdrawal syndrome






36. May protect against doxorubicin toxicity by scavenging free radicals






37. Atypical antipsychotic causing high prolactin levels






38. Antidote used in poisonings: copper (Wilson's disease) - lead - mercury - and arsenic






39. Barbiturates may precipitate this hematologic condition






40. Example of three antidepressants that are indicated for obsessive compulsive disorder






41. Anti - viral with a dose limiting toxicity of pancreatitis






42. Agents that block L- type calcium channel






43. Opioid available trans - dermally






44. Newer atypical antipsychotic used for bipolar disorder - known to cause weight gain - and adversely affect diabetes






45. Shock due to septicemia or myocardial infarction is made worse by






46. Inhibits conversion of cholesterol to pregnenolone therefore inhibiting corticosteroid synthesis






47. Activation of these receptors close Ca2+ ion channels to inhibit neurotransmitter release






48. Selective Alpha 1 blocker used for hypertension - BPH - may cause first dose orthostatic hypotension






49. Antidote used for opioid toxicity






50. Most inhaled anesthetics SE







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