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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. CCB with predominate effect on arteriole dilation






2. Names of three bisphosphonates available IV






3. Chelating agent used in Wilson's disease






4. Different steps of Phase I






5. Common SE of sulfonylureas - repaglinide - and nateglinide






6. Window between therapeutic effect and toxic effect






7. During Phase I these agents worsen muscle paralysis by succinylcholine - but during phase II they reverse the blockade produced by succinylcholine






8. Example of three antidepressants that are indicated for obsessive compulsive disorder






9. SE of beta blockers






10. IV Drug used Hypertensive Crisis






11. Acetaminophen only has






12. MOA of Cardiac glycosides (eg. digoxin)






13. Vitamins containing iron should Not be taken simultaneously with levothyroxine because






14. SE of Aspirin






15. Epinephrine is often mixed with a local anesthetic to






16. Reason ergot alkaloids are contraindicated in pregnancy






17. PCN active against pseudomonas






18. Ability of a drug to produce 100% of the maximum response regardless of the potency






19. Neurotransmitters affected by the action of antidepressants






20. Agent with long duration of action and is most likely to cause histamine release






21. Treatments available for nicotine addiction






22. Skeletal muscle agent that can block muscarinic receptors






23. Drug used in neuroleptic malignant syndrome






24. MOA of general anesthetics






25. Anti - seizure agent that induces formation of liver drug - metabolism enzymes - is teratogen and can cause craniofacial anomalies and spina bifida






26. Agent used in drug therapy of Parkinson's instead of Dopamine which has low bioavailability and does not cross the BBB






27. Treatment of atropine overdose and glaucoma (because lipid soluable). Enters the CNS rapidly and has a stimulant effect - which may lead to convulsions






28. Anti - androgen used for hirsutism in females






29. Anti - psychotics available in depot preparation






30. Reversal of blockade by neuromuscular blockers






31. 1st generation antihistamine that is least sedating






32. Cause dizziness - tachycardia - hypotension - and flushing






33. This produces 'dissociative anesthesia' - is a cardiovascular stimulant which may increases intracranial pressure - and hallucinations occur during recovery






34. New class of drugs that works by inhibiting absorption of intestinal cholesterol and can be given concurrently with the Statins






35. NSAID used in gout






36. Opioids used in anesthesia






37. Pyrimidine analog that causes 'Thymine - less death' given with leucovorin rescue






38. Thrombolytic used for acute MI and ischemic (non hemorrhagic) CVA






39. Drug of choice for myoclonic seizures






40. ACTH analog used for diagnosis of patients with corticosteroid abnormality






41. Major indication for H1 receptor antagonist






42. Decreases liver triglycerol synthesis






43. Endogenous insulin contains






44. This diuretic decreases aqueous secretion due to lack of HCO3- ion. Causes drowsiness and paresthesias - alkalinization of the urine may precipitate calcium salts - hypokalemia - acidosis






45. MOA of AGI's






46. Methyldopa is contraindicated in






47. Most important potential SE of metformin






48. Nonselective alpha - blocking drug - short acting and reversible - used for rebound HTN from rapid clonidine withdrawal - and Raynaud's phenomena






49. Drug used in ergot alkaloids overdose - ischemia and gangrene






50. Common toxicities of cisplatin