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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Drug causes teeth discoloration






2. Drugs of choice for generalized tonic - clonic and partial seizures






3. CCB with predominate effect on arteriole dilation






4. Antidote for salicylate intoxication






5. Inducers of Cytochrome P450 (CYP450)






6. The elimination of drug that occurs before it reaches the systemic circulation






7. Ultra long acting insulin - has over a day duration of action






8. The most common type of drug interaction of sedative hypnotics with other depressant medications






9. The most common neurologic abnormality in chronic alcoholics






10. Drug of choice for leprosy






11. Inhibit synaptic activity of primary afferents and spinal cord pain transmission neurons






12. Drug used in cancer therapy causes Cushing - like symptoms






13. Drugs of choice for status epilepticus






14. Longer acting benzodiazepines used in the management of withdrawal states of alcohol and other drugs






15. Agent for pernicious anemia






16. MOA of cisplatin






17. Agent used for megaloblastic anemia (but does Not reverse neurologic symptoms) and decrease neural tube defects during pregnancy






18. NSAID also available as an ophthalmic preparation






19. This is combined with L- dopa - inhibits DOPA decarboxylase (active only peripherally) which allows lower effective doses of L- dopa and allows for fewer SE's (GI distress - postural hypotension - and dyskinesias)






20. NSAID used in gout






21. SE of imipenem






22. Potassium sparing diuretics inhibit






23. MOA of corticosteroids






24. Antidote used for digitalis toxicity






25. Where are beta cells found in the pancreas?






26. These agents are congeners of Amphetamine

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27. All opioids except this agent (which has a muscarinic blocking action) cause pupillary constriction






28. Beta blockers partial agonist activity (intrinsic sympathomimetic activity) cause some bronchodilation and may have an advantage in treating patients with asthma






29. Direct vasodilator of arteriolar smooth muscle






30. Prolonged exposure to this inhaled anesthetic may lead to megaloblastic anemia






31. Strength of interaction between drug and its receptor






32. Drugs used in the management of angina






33. The fraction of administered dose of a drug that reaches systemic circulation






34. Agent having no effect on D2 receptors - blocks D4 - reserved for resistant schizophrenia - and can cause fatal agranulocytosis






35. Heparin (PTT) increases activity of






36. MOA of class III antiarrhythmics






37. Converted to more active form DHT by 5 alpha - reductase






38. HMG CoA reductase inhibitors are contraindicated in






39. SSRI indicated for premenstrual dysphoric disorder






40. Anti - viral with a dose limiting toxicity of pancreatitis






41. SE for ticlopidine






42. Removal of PCP may be aided






43. Inhaled anesthetic - less likely to lower blood pressure than other agents - and has the smallest effect on respiration






44. IV barbiturate used as a pre - op anesthetic






45. Interaction with this drug requires dose reduction of 6- MP






46. Some side effects of corticosteroids






47. Non - benzodiazepine used as an anxiolytic






48. Alpha 1selective blockers






49. This may enhance activity of local anesthetics






50. Major effect of benzodiazepines on sleep at high doses