SUBJECTS
|
BROWSE
|
CAREER CENTER
|
POPULAR
|
JOIN
|
LOGIN
Business Skills
|
Soft Skills
|
Basic Literacy
|
Certifications
About
|
Help
|
Privacy
|
Terms
|
Email
Search
Test your basic knowledge |
USMLE/COMLEX Step 1 Pharmacology One Liners
Start Test
Study First
Subjects
:
health-sciences
,
usmle-step-1
,
comlex
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. DOC for febrile seizures
Interleukin 11 (oprelvekin)
Bradykinin
Phenobarbital
Hepatic toxicity
2. Some of SSRIs' therapeutic effects beside depression
Nondepolarizing type antagonists
Dry cough - hyperkalemia
Ascending pathways
Panic attacks - social phobias - bulimia nervosa - and PMDD (premenstrual dysphoric disorder) - OCD
3. Neurotoxicity with isoniazid (INH) prevented by
Zafirlukast and montelukast
Nitrous oxide
Administration of Vit. B6 (pyridoxine)
Arginine
4. Inhibit angiotensin - converting enzyme (ACE)
Carbamazepine - gabapentin - lamotrigine - and valproic acid
Muscarinic blockers
ACE inhibitors
Maintenance dose (Cp*(CL/F))
5. Produces disulfiram - like reaction with ethanol
Pioglitazone - Rosiglitazone - Troglitazone (withdrawn/d from market)
Procarbazine
Most are thought to act at GABA- A receptor - chloride channel
Benztropine
6. SE of amrinone
C- peptide
Glucuronate - acetic acid - and glutathione sulfate
SSRIs
Thrombocytopenia
7. Difference between aspirin and other NSAIDS
Oxidation - reduction - hydrolysis
Aspirin irreversibly inhibits cyclooxygenase
Heparin induced thrombocytopenia (HIT)
Postsynaptic Mu receptors
8. SE of colchicine
Diazepam
Dimercaprol
Delavirdine - efavirenz - and ribavirin
Kidney and liver toxicity - diarrhea
9. Agent used in acutely decompensated CHF resembling natriuretic peptide
Minocycline
Nesiritide (Natrecor)
Succinylcholine
Aspirin
10. MOA of sildenafil (Viagra)
Tamsulosin (Flomax)
IV and IM (only LMW)
Reduce aqueous secretion
Inhibits phosphodiesterase -5 - enhancing effects of nitric oxide - activated increases in cGMP
11. Interact with microtubules (but unlike vinca which prevent disassembly of tubules) - it stabilizes tubulin and cells remain frozen in metaphase
Olanzapine - aripiprazole - and sertindole
Long acting cholinesterase inhibitors
Paclitaxel (taxol)
Dapsone - rifampin and clofazimine combination
12. Secondary amines that have less sedation and more excitation effect
PTU
Adenosine
Autocoids
Nortriptyline - Desipramine
13. What do alpha cells in the pancreas produce?
Glucagon
Excessive hypotension and kidney failure
Acarbose
Dopamine
14. Four main actions of NSAIDS
Anti - inflammatory - analgesia - antipyretic and antiplatelet activity
Aspirin - Nitrates - CCB - and Beta blockers
Rheumatic disease
Marijuana
15. Dopamine agonist used in hyperprolactinemia
Bromocriptine
Bleomycin
LD50
Valproic acid - carbamazepine - phenytoin and gabapentin
16. Antidote used for lead poisoning
Nausea
Dimercaprol - EDTA
Chloramphenicol
Sedation
17. Most common side effect of 1st generation antihistamines
Irreversibly blocking cyclooxygenase
sodium polystyrene sulfonate (Kayexalate)
Sedation
Magnesium sulfate
18. Shock due to septicemia or myocardial infarction is made worse by
Insulin
Increasing afterload and tissue perfusion declines
Older antipsychotic agents - D2 receptors
Ethinyl estradiol and mestranol
19. Agents for reduction of postpartum bleeding
Neutropenia and agranulocytosis
Lipoprotein lipase
Oxytocin - ergonovine and ergotamine
Ortho - Evra
20. Long acting sympathomimetic - sometimes used to improve urinary continence in children and elderly with enuresis
Allopurinol
Nitroglycerin sublingual tablets
Neostigmine
Ephedrine
21. MOA of neuroleptics
Ganciclovir
Dopamine blockade
Aspirin
Insulin
22. SE of tPA
Tertiary amines
NSAIDS
Diphendydramine
Cerebral hemorrhage
23. Presynaptic Alpha 2 agonist used in HTN - and acts centrally
Mast cell stabilizer
Digibind
Clonidine - and methyldopa
Terfenadine and astemizole (have been removed from the market)
24. Anti - rheumatic agent also used for Chron's disease
Pamidronate - zoledronate - ibandronate
Lorazepam - oxazepam - and temazepam
Infliximab
Increase the DURATION of GABA- mediated chloride ion channels
25. Allopurinol treats chronic gout by decreasing uric acid production by inhibiting
Naloxone (IV) - naltrexone (PO)
Cefixime (3rd) generation
Xanthine oxidase
Cosyntropin
26. Somatotropin (GH) analog used in GH deficiency (dwarfism)
Fluoxetine
Odansetron
Buprenorphine
Somatrem
27. Antidote for arsenic - mercury - lead - and gold poisoning
Clonazepam
Ethanol - Barbiturates - and Benzodiazepines
Dimercaprol
inhibits Na+/K+/2Cl - cotransport
28. MOA of penicillin
Block cell wall synthesis by inhibiting peptidoglycan cross - linkage
Tolerance
Phenoxybenzamine
Gynecomastia
29. TCA used in obsessive compulsive disorder (OCD) - most significant of TCA's for risk of seizure - weight gain - and neuropsychiatric signs and symptoms
Low therapeutic index
Terfenadine and astemizole (have been removed from the market)
Ketamine
Clomipramine
30. Agent effective in physiologic and essential tremor
Propranolol
Arginine
Bile acid - binding resins
Flumazenil
31. Losartan and valsartan block
Thioridazine
Serum ammonia and LFT's
Pramipexole and ropinirole
Angiotensin receptor
32. Different steps of Phase I
Oxidation - reduction - hydrolysis
Buspirone
Benztropine
Halothane
33. Antidote for salicylate intoxication
Lupus - like syndrome
Ketanserin cyproheptadine - and phenoxybenzamine
Alkalinize urine - dialysis
Ganciclovir - zidovudine - saquinavir - and interferon
34. MOA of AGI's
Adriamycin (doxorubicin) +bleomycin - vinblastine +dacarbazine
Chlorpropamide - tolbutamide - tolazamide - etc.
Act on intestine - delay digestion and absorption of glucose formed from digestion of starch and disacchrides
Norepinephrine and serotonin
35. MOA of Bisphosphonates
Affect calcium - potassium - and sodium channels
Dicyclomine - methscopolamine
Valproic acid
Inhibits osteoclast bone resorption
36. Anti - rheumatic agent also used for ulcerative colitis
Fexofenadine - loratadine - and cetirizine
Sulfasalazine
Red urine discoloration
Aspirin irreversibly inhibits cyclooxygenase
37. Agent used for closure of patent ductus arteriosus
Thiopental
Valproic acid
Imipramine
Indomethacin
38. Blows DNA (breaks DNA strands) - limiting SE is pulmonary fibrosis
Propoxyphene
Bleomycin
Degradation of fibrin clots and are administered IV
Morphine and fentanyl
39. Site of action of loop diuretics
Thick ascending limb
Dobutamine
sulfamethoxazole/ trimethoprim
Decreases protein synthesis by inhibiting 30S ribosome
40. Only direct acting agent that is very lipid soluble and used in glaucoma
Dicyclomine - methscopolamine
Ganciclovir
Pilocarpine
Phenoxybenzamine
41. Term for a narrow margin of safety
Na+/K+ exchange
Naltrexone
Minocycline
Low therapeutic index
42. Agents used in treatment of carcinoid tumor
Pyridostigmine
Lispro (Humalog) - aspart - glulisine
Ketanserin cyproheptadine - and phenoxybenzamine
Beta -1 selective blockers
43. Concern using lithium
None
Infants - closed angle glaucoma - prostatic hypertrophy
Low therapeutic index
Platelet aggregation inhibition
44. TCA with greatest sedation of this group - and marked antimuscarinic effects - used for sleep
Hypokalemia
Doxepin
Acetazolamide
Ezetimibe (Zetia)
45. Atypical antipsychotic causing high prolactin levels
DUMBELSS (diarrhea - urination - miosis - bronchoconstriction - excitation of skeletal muscle and CNS - lacrimation - salivation - and sweating)
Risperidone
Nandrolone - oxymetholone - and oxandrolone
Gynecomastia
46. Fluoride released by metabolism of this inhaled anesthetic may cause renal insufficiency
Elderly patients
Folic acid
Cholinesterase regenerators - pralidoxime
Methoxyflurane
47. Drug notorious for causing pseudomembranous colitis
Imipramine
Reduce inhibition - suppress anxiety - and produce relaxation
Clindamycin
Relax vascular smooth muscle - at low doses dilate veins and at high doses dilate arterioles
48. MOA for Ethosuximide
Dopamine blockade
Ethanol - fomepizole
Calcium channels
Sedation
49. Selective estrogen receptor modulator (SERM) used for prevention of osteoporosis and prophylaxis in women with risk factors for breast cancer
Raloxifene
Aspirin - metoprolol
Inhibit DNA gyrase
Phenylephrine
50. Anti - estrogen used for estrogen receptor + breast cancer
Octreotide
Dry cough - hyperkalemia
Tamoxifen
Hyperuricemia - hypokalemia and ototoxicity
Sorry!:) No result found.
Can you answer 50 questions in 15 minutes?
Let me suggest you:
Browse all subjects
Browse all tests
Most popular tests
Major Subjects
Tests & Exams
AP
CLEP
DSST
GRE
SAT
GMAT
Certifications
CISSP go to https://www.isc2.org/
PMP
ITIL
RHCE
MCTS
More...
IT Skills
Android Programming
Data Modeling
Objective C Programming
Basic Python Programming
Adobe Illustrator
More...
Business Skills
Advertising Techniques
Business Accounting Basics
Business Strategy
Human Resource Management
Marketing Basics
More...
Soft Skills
Body Language
People Skills
Public Speaking
Persuasion
Job Hunting And Resumes
More...
Vocabulary
GRE Vocab
SAT Vocab
TOEFL Essential Vocab
Basic English Words For All
Global Words You Should Know
Business English
More...
Languages
AP German Vocab
AP Latin Vocab
SAT Subject Test: French
Italian Survival
Norwegian Survival
More...
Engineering
Audio Engineering
Computer Science Engineering
Aerospace Engineering
Chemical Engineering
Structural Engineering
More...
Health Sciences
Basic Nursing Skills
Health Science Language Fundamentals
Veterinary Technology Medical Language
Cardiology
Clinical Surgery
More...
English
Grammar Fundamentals
Literary And Rhetorical Vocab
Elements Of Style Vocab
Introduction To English Major
Complete Advanced Sentences
Literature
Homonyms
More...
Math
Algebra Formulas
Basic Arithmetic: Measurements
Metric Conversions
Geometric Properties
Important Math Facts
Number Sense Vocab
Business Math
More...
Other Major Subjects
Science
Economics
History
Law
Performing-arts
Cooking
Logic & Reasoning
Trivia
Browse all subjects
Browse all tests
Most popular tests