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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Anti - arrhythmics that decrease mortality






2. MOA of Leflunomide (newer agent)






3. Class of anti - arrhythmics that has a pro - arrhythmic effect (CAST trial) - therefore are used as last line agents






4. Chronic high dose abuse of nicotine leads to






5. This beta blocker is the longest acting






6. Reason troglitazone was withdrawn from market






7. Non - steroidal estrogen agonist causes clear cell adenocarcinoma of the vagina in daughters of women who used it during pregnancy






8. Anti - estrogen used for estrogen receptor + breast cancer






9. Cause dizziness - tachycardia - hypotension - and flushing






10. MOA of class III antiarrhythmics






11. MOA of tetracycline






12. Agent used for acute muscle spasm






13. Class of antibiotics that have 10% cross sensitivity with penicillins






14. Agent used in drug therapy of Parkinson's instead of Dopamine which has low bioavailability and does not cross the BBB






15. Benzodiazepine used for anxiety






16. SE for Lamotrigine






17. DOC for status epilepticus






18. CCB contraindicated in CHF






19. NSAID contraindicated in gout






20. Antidote for tissue plasminogen activator (t - PA) - streptokinase






21. Benzodiazepine that has efficacy against absence seizures and in anxiety states - such as agoraphobia






22. Reduced seizure threshold






23. MOA of AGI's






24. Prolonged exposure to this inhaled anesthetic may lead to megaloblastic anemia






25. Drug used for MRSA






26. Anti - psychotics available in depot preparation






27. Chemical antagonists that bind to the inhibitor of ACh Estrace and displace the enzyme (if aging has not occurred)






28. Partial opioid agonist - considered a strong analgesic - has a long duration of action and is resistant to naloxone reversal






29. Aromatase inhibitor used in breast cancer






30. Barbiturates may precipitate this hematologic condition






31. Cholinomimetics that increase outflow - open trabecular meshwork - and cause ciliary muscle contraction






32. Diuretic used to treat primary aldosteronism






33. Activation of these receptors close Ca2+ ion channels to inhibit neurotransmitter release






34. Beta 1 agonists used in acute CHF






35. Pungent inhaled anesthetic which leads to high incidence of coughing and vasospasm






36. DOC for RSV






37. Fluoride released by metabolism of this inhaled anesthetic may cause renal insufficiency






38. Chronic orthostatic hypotension can be treated with






39. Agent used to treat MI and to reduce incidence of subsequent MI






40. ADH agonist used for pituitary diabetes insipidus






41. MOA for Valproic acid at high doses






42. Microtubule inhibitor that causes peripheral neuropathy - foot drop (eg. ataxia) - and 'pins and needles' sensation






43. Anti - seizure agent that exhibits non - linear metabolism - highly protein bound - causes fetal hydantoin syndrome - and stimulates hepatic metabolism






44. What do delta cells in the pancreas produce?






45. Antidepressant associated with neuroleptic malignant syndrome






46. Proteins that prevent action of tumor necrosis factor alpha (TNF- alpha)






47. Dopamine (DA) agonist (for Parkinson's disease) - used also for hyperprolactinemia






48. SE for ticlopidine






49. Long acting insulin






50. Antipsychotics that reduce positive symptoms only