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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Drugs decrease intestinal absorption of cholesterol






2. Toxicity caused by nitroprusside and treatment






3. Dopamine (DA) agonist (for Parkinson's disease) - used also for hyperprolactinemia






4. Alpha - glucosidase inhibitor associated with elevation of LFT's






5. MOA of sulfonamides






6. Long acting insulin






7. Second generation sulfonylurea






8. Agent that inhibits alcohol dyhydrogenase and its clinical use






9. Selective estrogen receptor modulator (SERM) used for prevention of osteoporosis and prophylaxis in women with risk factors for breast cancer






10. Anticancer drug also used in RA - produces acrolein in urine that leads to hemorrhagic cystitis






11. Inducers of Cytochrome P450 (CYP450)






12. SE of penicillamine






13. Somatotropin (GH) analog used in GH deficiency (dwarfism)






14. Clinical uses of these agents include treatment of HTN - angina - arrhythmias - chronic CHF - and selected post MI patients






15. One depolarizing blocker that causes continuous depolarization and results in muscle relaxation and paralysis - causes muscle pain postoperatively and myoglobinuria may occur






16. Most frequent route of metabolism






17. MOA of thiazolindinediones






18. Toxicity of organophosphate:






19. Neurologic SE of benzodiazepines






20. Radio contrast media that inhibits the conversion of T4 to T3






21. System that increases in activity with chronic ethanol exposure and may contribute to tolerance






22. Inhibitors of CYP450






23. Bleomycin+vinblastine+etoposide+cisplatin produce almost a 100% response when all agents are used for this neoplasm






24. Drugs that can be used for infantile spasms






25. Antidote for beta - blockers and hypoglycemia






26. This produces 'dissociative anesthesia' - is a cardiovascular stimulant which may increases intracranial pressure - and hallucinations occur during recovery






27. Relates the amount of drug in the body to the plasma concentration






28. Antidepressant also used for sleep that causes priapism






29. Associated with an increased incidence of cataracts in patients treated for glaucoma






30. Some cell cycle non - specific drugs






31. Used for hairy cell leukemia; it stimulates NK cells






32. GHRH analog used as diagnostic agent






33. Thrombolytic that can cause allergic reaction






34. Antidote for arsenic - mercury - lead - and gold poisoning






35. Prototypical drug is atropine






36. Anti - psychotics available in depot preparation






37. Antiarrhythmic effective in most types of arrhythmia






38. Most common side effect of 1st generation antihistamines






39. MOA of nystatin






40. Mineralocorticoids






41. Drug causes teeth discoloration






42. Fibrates (gemfibrozil) increase activity of






43. Atypical antipsychotic causing high prolactin levels






44. Tolerance to all effects of opioid agonists can develop except






45. Opioid antagonist that is given IV and had short DOA






46. Muscarinic antagonist used in asthma






47. Methyldopa is contraindicated in






48. Toxic effect of anticancer drug can be lessened by rescue agents






49. Methylxanthine derivative used as a remedy for intermittent claudication






50. Common SE of tamoxifen and raloxifene