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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Anti - arrhythmic with 15 second duration of action






2. Atropine fever is the most dangerous effect and can be lethal in this population group






3. COX 2 inhibitors should be used cautiously in pts with






4. Enhances dopaminergic neurotransmission SE's include CNS excitation - acute toxic psychosis and livedo reticularis






5. Indirect - Acting ACh Agonist - alcohol - short DOA and used in diagnosis of myasthenia gravis






6. Leads to respiratory depression progressing to coma and death






7. Carbonic anhydrase inhibitor






8. GnRH agonist used for infertility or different types of CA depending on pulsatile or steady usage respectively






9. Endogenous substances commonly interpreted as histamine - serotonin - prostaglandins - and vasoactive peptides






10. Direct vasodilator of arteriolar smooth muscle






11. H1 blocker that is also a serotonin antagonist






12. Drug used for N. gonorrhea in females






13. T3 compound less widely used






14. Agent for pernicious anemia






15. Side effects seen with tricyclic antidepressants






16. MOA of lovastatin (STATIN)






17. Peptide drug used to treat CHF






18. Anticoagulant of choice in pregnancy






19. Cephalosporins able to cross the BBB






20. These agents are congeners of Amphetamine

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21. Anti - psychotic not shown to cause tardive dyskinesia






22. Interaction with this drug requires dose reduction of 6- MP






23. Median toxic dose required for a toxic effect in 50% of the population






24. Class of drugs whose MOA utilizes ligand gated ion channels






25. Long acting beta 2 agonist used in asthma






26. SE of minoxidil






27. Sulfonylurea Not recommended for elderly because of very long half life






28. Another pneumonic for anticholinergic toxicity

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29. MOA of nesiritide






30. Antidepressants with no effect on BP - no sedation






31. Antidote for digoxin toxicity






32. Inhibits conversion of cholesterol to pregnenolone therefore inhibiting corticosteroid synthesis






33. Agents having higher sedation and antimuscarinic effects than other TCA's






34. Readily detected markers that may assist in diagnosis of the cause of a drug overdose include






35. Drug of choice for leprosy






36. The fraction of administered dose of a drug that reaches systemic circulation






37. DOC for status epilepticus






38. Intermediate acting glucocorticoids






39. Agent used for closure of patent ductus arteriosus






40. Increase bone density - also being tested for breast CA prophylaxis






41. Analog of hypoxanthine - needs HGPRTase for activation






42. For rebound HTN from rapid clonidine withdrawal






43. Used for Addison's disease - Congenital Adrenal Hyperplasia (CAH) - inflammation - allergies - and asthma (as a local inhalation)






44. Mechanisms of action for Phenytoin - Carbamazepine - Lamotrigine






45. ABVD regimen used for HD - but appears less likely to cause sterility and secondary malignancies than MOPP






46. Drugs decrease intestinal absorption of cholesterol






47. Anti - seizure drugs used also for bipolar affective disorder (BAD)






48. Inhaled anesthetics are myocardial depressants






49. GHRH analog used as diagnostic agent






50. MOA of general anesthetics