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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Drug of choice for leprosy






2. Inhaled anesthetic - less likely to lower blood pressure than other agents - and has the smallest effect on respiration






3. Drug used for N. gonorrhea in females






4. Another pneumonic for anticholinergic toxicity


5. Agent used for acute muscle spasm






6. Major SE of bisphosphonates






7. Difference between aspirin and other NSAIDS






8. This is combined with L- dopa - inhibits DOPA decarboxylase (active only peripherally) which allows lower effective doses of L- dopa and allows for fewer SE's (GI distress - postural hypotension - and dyskinesias)






9. Moderate opioid agonists






10. The ratio of the rate of elimination of a drug to its plasma concentration






11. This parenteral beta blocker is a short acting (minutes)






12. Only phenothiazine not exerting antiemetic effects - can cause visual impairment due to retinal deposits - and high doses have been associated with ventricular arrhythmias






13. Peakless ling acting insulin






14. Inhaled anesthetic that may sensitize the myocardium to arrhythmogenic effects of catecholamines and has produced hepatitis






15. Common SE of tamoxifen and raloxifene






16. Some cell cycle non - specific drugs






17. Antidepressant which is inhibitor of CYP450 enzymes and may be associated with hepatic failure






18. Antiarrhythmic that exhibits Class II and III properties






19. Drug ofter used in combination with TNF - alpha inhitors for RA






20. Scabicide organophosphate






21. Antidote used for beta agonist toxicity (eg. Metaproterenol)






22. Treatment of myasthenia gravis






23. Causes bone marrow suppression






24. Antidepressant associated with neuroleptic malignant syndrome






25. Drug used in neuroleptic malignant syndrome






26. Names of three bisphosphonates available IV






27. Important in synthesis of glucose to glycogen in the liver






28. Arterial vasodilator that works by opening K+ channels






29. W/D from this drug causes anxiety and mental discomfort






30. SE of Thiazolindinediones






31. Agent used for anemias associated with renal failure






32. SE for ganciclovir






33. Term for a high margin of safety






34. NSAID that is used for acute condition - such as pre - op anesthesia and has limited duration (<5 days) of use due to nephrotoxicity






35. Opioids used in anesthesia






36. The most important sign of withdrawal syndrome






37. Overdoses of this agent with powerful vasoconstrictive action may result in fatalities from arrhythmias - seizures - respiratory depression - or severe HTN (MI and stroke)


38. Good hypnotic activity with less CNS SE than most benzodiazepines






39. Heterocyclic antidepressants least likely to affect sexual performance - used for management of nicotine withdrawal - SE's include dizziness - dry mouth - aggravation of psychosis - and seizures






40. Most dangerous of the currently popular hallucinogenic drugs - OD leads to nystagmus - marked hypertension - and seizures - presence of both horizontal and vertical nystagmus is pathognomonic






41. SE of penicillamine






42. This is the drug of choice for anaphylactic shock






43. DOC for paroxysmal supraventricular tachycardia (PSVT)






44. Very rapid acting insulin - having fastest onset and shortest duration of action






45. Nitroprusside vasodilates






46. Withdrawal from this drug causes lethargy - irritability - and headache






47. These agents are congeners of Amphetamine


48. Agents that block L- type calcium channel






49. Benzodiazepine that has efficacy against absence seizures and in anxiety states - such as agoraphobia






50. Important in muscle and adipose tissue for glucose transport across muscles and TG storage by lipoprotein lipase activation