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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Anti - seizure drugs used also for pain of neuropathic orgin






2. Alpha - glucosidase inhibitor associated with elevation of LFT's






3. Major SE of insulin






4. Chelating agent used in Wilson's disease






5. SE of Aspirin






6. Antidote used for organophosphate/anticholinesterase poisoning






7. SE of loop (furosemide) diuretics






8. These Beta blockers decrease aqueous secretion






9. Lethal arrhythmias resulting from concurrent therapy with azole fungals (metabolized by CYP 3A4) and these antihistamines which inhibit the 3A4 iso - enzyme.






10. Inhibit angiotensin - converting enzyme (ACE)






11. 5HT-3 antagonist used in chemotherapeutic induced emesis






12. Regimen used for non - Hodgkin's lymphoma






13. Syndrome of hypersecretion of gastric acid and pepsin usually caused by gastrinoma; it is associated with severe peptic ulceration and diarrhea






14. SE of hydralazine






15. Interact with microtubules (but unlike vinca which prevent disassembly of tubules) - it stabilizes tubulin and cells remain frozen in metaphase






16. Term for a narrow margin of safety






17. Treatment for TB patients (think RIPE)






18. Proteins that prevent action of tumor necrosis factor alpha (TNF- alpha)






19. Major indication for H1 receptor antagonist






20. Newer atypical antipsychotic used for bipolar disorder - known to cause weight gain - and adversely affect diabetes






21. Aspirin reduces mortality in unstable angina by






22. MOA of penicillin






23. This agent has greater affinity for muscarinic receptors and used for postoperative and neurogenic ileus and urinary retention






24. Some cell cycle specific anti - cancer drugs






25. Incidence of hyoglycemia with metformin






26. Inhibitor of MAO type B which metabolizes dopamine - used adjunct to levodopa or as sole agent in newly diagnosed patients






27. Anti - thyroid drugs






28. Chemical antagonists that bind to the inhibitor of ACh Estrace and displace the enzyme (if aging has not occurred)






29. Dose which is lethal to 50% of the population






30. SE of ergot alkaloids






31. SE of tPA






32. Drug increases the renal clearance hence decreases levels of lithium






33. Cutaneous flush and be reduced by pretreatment with






34. Products of Phase II conjugation






35. MOA action of cromolyn






36. Antidepressant inhibiting norepinephrine - serotonin - and dopamine reuptake






37. Causes bone marrow suppression






38. This beta blocker is the longest acting






39. Chronic orthostatic hypotension can be treated with






40. The most important sign of withdrawal syndrome






41. Selectivity of a drug for its receptor






42. Anti - seizure agent that exhibits non - linear metabolism - highly protein bound - causes fetal hydantoin syndrome - and stimulates hepatic metabolism






43. Tolerance to all effects of opioid agonists can develop except






44. The ratio of the rate of elimination of a drug to its plasma concentration






45. Converted to more active form DHT by 5 alpha - reductase






46. SelectiveB1 Receptor blockers that may be useful in treating patients even though they have asthma






47. These agents decrease blood flow or increase blood pressure - are local decongestants - and used in therapy of spinal shock (temporary maintenance of blood pressure which may help maintain perfusion






48. Where are beta cells found in the pancreas?






49. Drug notorious for causing pseudomembranous colitis






50. This beta blocker lacks local anesthetic activity (a property which decreases protective reflexes and increases the risk of corneal ulceration) and used in treating glaucoma