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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Common SE of tamoxifen and raloxifene






2. Drug used for N. gonorrhea in females






3. Antidote used for tricyclic antidepressants (TCA)






4. Inhaled anesthetics metabolized by liver enzymes which has a major role in the toxicity of these agents






5. Used for Cushing's syndrome (increased corticosteroid)






6. Nonselective alpha - blocking drug - long acting and irreversible - and used to treat pheochromocytoma. Blocks 5- HT - so occasionaly used for carcinoid tumor. Blocks H1 and used in mastocytosis






7. TCA used in chronic pain - enuresis - and ADD






8. Agent for pernicious anemia






9. Common side effect of Rifampin






10. Treatment of patients with prior episodes of thrombocytopenia after a cycle of cancer chemotherapy






11. Opioid associated with respiratory depression - but is used in high risk patients who may not survive full general anesthetia






12. Permanently cures thyrotoxicosis - patients will need thyroid replacement therapy thereafter. Contraindicated in pregnancy






13. MOA of loop diuretics






14. Methyldopa is contraindicated in






15. Anti - androgen used for prostate cancer






16. Agents having higher sedation and antimuscarinic effects than other TCA's






17. Cholinomimetics that increase outflow - open trabecular meshwork - and cause ciliary muscle contraction






18. Antipsychotic used in the treatment of psychiatric symptoms in patients with dementia






19. Life threatening cardiac event that prolong QT leads to






20. Drug of choice for myoclonic seizures






21. NSAID used in gout






22. Non - selective Alpha1blockers use to treat pheochromocytoma






23. SE of clonidine






24. HIV med used to reduce transmission during birth






25. Heterocyclic antidepressants least likely to affect sexual performance - used for management of nicotine withdrawal - SE's include dizziness - dry mouth - aggravation of psychosis - and seizures






26. Anticancer drug also used in RA - produces acrolein in urine that leads to hemorrhagic cystitis






27. SE of OCs






28. Synthetic analog of ADH hormone used for diabetes insipidus and nocturnal enuresis






29. Irreversible condition resulting from the use of antipsychotics - reserpine at high doses - and MPTP (by- product of illicit meperidine analog)






30. Treatment of myasthenia gravis






31. Agents that reduce heart rate - contractility - and O2 demand






32. Mast cells to reduce release of hisamine and inflammatory mediators






33. Prototype antagonist of H1 and H2 receptors






34. GHRH analog used as diagnostic agent






35. This produces 'dissociative anesthesia' - is a cardiovascular stimulant which may increases intracranial pressure - and hallucinations occur during recovery






36. ACTH analog used for diagnosis of patients with corticosteroid abnormality






37. H1 antagonist used in motion sickness






38. Interferes with activity of T- lymphocytes






39. Antidepressant which is inhibitor of CYP450 enzymes and may be associated with hepatic failure






40. Most widely used thyroid drugs such as Synthroid and Levoxyl contain






41. Bronchodilation in asthma and COPD






42. Skeletal muscle agent that undergoes Hofmann elimination (breaks down spontaneously)






43. Constant low dose of estrogen and increasing dose of progestin for 21 days (last 5 days are sugar pills or iron prep)






44. Chelating agent used in Wilson's disease






45. Type of kinetics when a constant percentage of substrate is metabolized per unit time






46. Selectivity of a drug for its receptor






47. Agent used for closure of patent ductus arteriosus






48. Hormone inhibiting prolactin release






49. Thyroxine dose may need to be increased in hypothyroid patient during pregnancy because






50. Meningitis prophylaxis in exposed patients