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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Enhances dopaminergic neurotransmission SE's include CNS excitation - acute toxic psychosis and livedo reticularis






2. HIV antiviral class known to have severe drug interactions by causing inhibition of metabolism






3. Sympathetic agent which stimulates heart rate and can dilate vessels in skeletal muscle at low doses






4. MAOI should not be administered with SSRI's or potent TCA's due to development of this condition






5. SSRI with long T1/2 and can be administered once weekly for maintenance - not acute tx






6. Important in synthesis of glucose to glycogen in the liver






7. Cholinomimetics that increase outflow - open trabecular meshwork - and cause ciliary muscle contraction






8. Antipsychotic having the weakest autonomic effects






9. SE of phenytoin






10. SE of methyldopa

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11. Used for prevention of postmenopausal osteoporosis in women






12. Alpha 1selective blockers






13. Products of Phase II conjugation






14. Bronchodilation in asthma and COPD






15. Anti - psychotics available in depot preparation






16. Drug that causes contraction of the uterus






17. Route of administration of warfarin






18. Inhibitor of leukotrienes (LTD4) receptors and used in asthma






19. This agent may cause more severe - rapid and intense symptoms to a recovering addict






20. Beta 1 agonist toxicity






21. Weak opioid agonist - poor analgesic - its overdose can cause severe toxicity including respiratory depression - circulatory collapse - pulmonary edema - and seizures






22. All antidepressants have roughly the same efficacy in treating depression - agents are chosen based on these criterion






23. Anti - androgen used for hirsutism in females






24. Inhaled anesthetic that may sensitize the myocardium to arrhythmogenic effects of catecholamines and has produced hepatitis






25. Dopamine agonist used in hyperprolactinemia






26. Arterial vasodilator that works by opening K+ channels






27. B- blockers that are more cardioselective






28. Some cell cycle non - specific drugs






29. Opioids used in anesthesia






30. Thrombolytic that can cause allergic reaction






31. Another pneumonic for anticholinergic toxicity

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32. Inhaled anesthetic causes peripheral vasodilation






33. SE for Lamotrigine






34. Tolerance is marked and abstinence syndrome occurs






35. Common toxicities of cisplatin






36. Strength of interaction between drug and its receptor






37. Associated with an increased incidence of cataracts in patients treated for glaucoma






38. Longer acting local anesthetics which are less dependent on vasoconstrictors






39. Agent with zero - order kinetics






40. 1st generation antihistamine that is highly sedating






41. DOC for paroxysmal supraventricular tachycardia; has high efficacy and short duration of action






42. Cardioselective Beta 1- blockers






43. Newer estrogen receptor antagonist used in advanced breast cancer






44. Anticancer drug also used in RA - produces acrolein in urine that leads to hemorrhagic cystitis






45. Diuretic used to antagonize aldosterone receptors






46. Skeletal muscle agent that can block muscarinic receptors






47. Prototypical drug is atropine






48. Nitrate used for acute anginal attacks






49. SE of amrinone






50. Enzyme that metabolizes acetaldehyde to acetate