SUBJECTS
|
BROWSE
|
CAREER CENTER
|
POPULAR
|
JOIN
|
LOGIN
Business Skills
|
Soft Skills
|
Basic Literacy
|
Certifications
About
|
Help
|
Privacy
|
Terms
|
Email
Search
Test your basic knowledge |
USMLE/COMLEX Step 1 Pharmacology One Liners
Start Test
Study First
Subjects
:
health-sciences
,
usmle-step-1
,
comlex
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Benzodiazepine that has efficacy against absence seizures and in anxiety states - such as agoraphobia
Insulin glargine
Maintenance dose (Cp*(CL/F))
Tissue plasmin activator
Clonazepam
2. Difference between aspirin and other NSAIDS
Glucagon
Diazepam
Aspirin irreversibly inhibits cyclooxygenase
Ethanol
3. Prototype antagonist of H1 and H2 receptors
Diphenhydramine and cimetridine - respectively
Bromocriptine
Minimum alveolar anesthetic concentration (MAC)
Barbiturates - phenytoin - carbamazepine - and rifampin
4. Treatment of myasthenia gravis
Cimetidine
Pyridostigmine
Kidneys
Succinylcholine
5. Drug of choice for leprosy
Potency
Hallucinations resembling psychosis
Dapsone - rifampin and clofazimine combination
Clindamycin
6. SE of imipenem
Seizures
Atropine
Metformin
ED50
7. Non - benzodiazepine used as an anxiolytic
Excessive hypotension and kidney failure
Buspirone
Uterine contractions
Olanzapine
8. Antivirals associated with neutropenia
Torsades de pointes
Ganciclovir - zidovudine - saquinavir - and interferon
Benztropine
Therapeutic index
9. Agent that inhibits hepatic metabolism - is hepatotoxic and teratogen that can cause neural tube defects and gastrointestinal distress
Pyridostigmine
Indomethacin
Valproic acid
Beta blockers
10. DOC for management of acute ventricular arrhythmias
Propranolol
Amiodarone
Pralidoxime - atropine
Gingival hyperplasia
11. Product of proinsulin cleavage used to assess insulin abuse
C- peptide
Smooth muscle; stomach - heart - and mast cells; nerve endings - CNS respectively
Celecoxib
Naloxone
12. DOC for Legionnaires' disease
Entacapone and Tolcapone
Erythromycin
Nifedipine
Baclofen
13. Phosphodiesterase inhibitors that increase mortality and have been found to have NO beneficial effects
Nephrotoxicity
Amrinone and milrinone
Vitamin K and Fresh frozen plasma (FFP)
Cimetidine - ketoconazole - erythromycin - isoniazid and grapefruit
14. Antidote used for organophosphate/anticholinesterase poisoning
Propofol
Parathion
Carvedilol
Atropine - pralidoxime (2- PAM)
15. Enhances dopaminergic neurotransmission SE's include CNS excitation - acute toxic psychosis and livedo reticularis
Diethylstilbestrol (DES)
Testosterone
Amantadine
Lactic acidosis
16. Drug that inhibits alcohol dehydrogenase and is used in ethylene glycol exposure
Fomepizole
Lorazepam - oxazepam - and temazepam
DUMBELSS (diarrhea - urination - miosis - bronchoconstriction - excitation of skeletal muscle and CNS - lacrimation - salivation - and sweating)
Buspirone
17. Treatment with cancer chemotherapy at high doses every 3-4 weeks - too toxic to be used continuously
Lupus - like syndrome
Pulse therapy
Gabapentin
Carboplatin
18. Monitoring parameter to obtain before initiation of STATINS
Warning
: Invalid argument supplied for foreach() in
/var/www/html/basicversity.com/show_quiz.php
on line
183
19. Pungent inhaled anesthetic which leads to high incidence of coughing and vasospasm
Nephrotoxicity
Cytomel
Desflurane
Dipyridamole
20. DOC for influenza A
Amantadine
Dopamine
Somatrem
Red urine discoloration
21. Different steps of Phase I
Cocaine and benzocaine
Adalimumab - infliximab and etanercept
Oxidation - reduction - hydrolysis
Radioactive iodine
22. Newer estrogen receptor antagonist used in advanced breast cancer
Tetrabenazine (amine depleting drug) - Haloperidol (antipsychotic)
Efficacy
Toremifene (Fareston)
GLUT 2
23. Chelating agent used in Wilson's disease
Amphetamines
Penicillamine
Physostigmine
Cyclophosphamide
24. Muscarinic antagonist used in asthma
Organic nitrites
Stimulates cGMP which leads to vascular smooth muscle relaxation
Didanosine
Ipratropium
25. Agent more frequently associated with extrapyramidal side effects that can be treated with benzodiazepine - diphenhydramine or muscarinic blocker
N- acetylcysteine (Mucomyst)
Ability to cross the placenta
Ortho - Evra
Haloperidol
26. Common SE of spironolactone
Prednisone - methylprednisolone - prednisolone - and triamcinolone
Gynecomastia and hyperkalemia
Mostly in the brain - and they mediate synaptic inhibition via increased K+ conductance
Corticosteroids
27. Nitrate used to prevent further attacks
Nitrous oxide
Mifepristone (RU-486)
Oral and transdermal forms of nitroglycerin
Demeclocycline
28. Treatment for opioid addiction
Carbenicillin - piperacillin and ticarcillin
Ethanol - Barbiturates - and Benzodiazepines
Methadone - followed by slow dose reduction
GABA- related targets
29. Atropine fever is the most dangerous effect and can be lethal in this population group
Inhibition of protein synthesis at the 50s subunit of ribosome
Acarbose - miglitol
Monamine oxidase inhibitors
Infants
30. Non - selective Beta - blocker also used for migraine prophylaxis
Carbidopa
Propranolol
Sinus tachycardia and serious arrhythmias
N- acetylcysteine
31. Drugs that can be used for infantile spasms
Corticosteroids
Thrombocytopenic purpura - and CINCHONISM
Aldehyde dehydrogenase
Tetracaine and bupivacaine
32. Major drug interaction with Quinidine
Ticlopidine
Diazepam - Flurazepam - chlordiazepoxide - and clorazepate
Increases concentration of Digoxin
Urinary acidification and activated charcoal or continual nasogastric suction
33. DOC for herpes and its MOA
Tamoxifen
Adriamycin (doxorubicin) +bleomycin - vinblastine +dacarbazine
Acyclovir; incorporated into viral DNA and chain termination
5- flouracil (5- FU)
34. Peptide drug used to treat CHF
Dimercaprol
Reducing preload
Nesiritide (BNP)
Beta - blockers such as propranolol
35. Dopamine (DA) agonist (for Parkinson's disease) - used also for hyperprolactinemia
Nicotine
Hydralazine
Rifampin - Isoniazid - Pyrazinamide - and Ethambutol
Bromocriptine
36. Prevents thrombosis in patients with artificial heart valve
Dipyridamole
Low - potency typical antipsychotics and clozapine
Methotrexate
Hot flashes
37. Major indication for H1 receptor antagonist
Fexofenadine - loratadine - and cetirizine
Bone marrow and teeth discoloration for children under 8 years of age
Streptokinase
Use in IgE mediated allergic reaction
38. Agent used neutropenia especially after chemotherapy
Valproic acid
G- CSF (filgrastim) and GM- CSF (sargramostim)
Bradycardia - SEXUAL DYSFUNCTION - decrease in HDL - and increase in Triglycerols (TG)
Noncompetitive antagonist
39. Activation of these receptors close Ca2+ ion channels to inhibit neurotransmitter release
Hallucinations resembling psychosis
Haloperidol
Presynaptic mu - delta - and kappa receptors
Osteopenia - impaired wound healing - inc. risk of infection - inc. appetite - HTN - edema - PUD - euphoria - psychosis - stria - thinning of skin
40. SE for ticlopidine
Vasodilation
Mivacurium
Hypokalemia
Neutropenia and agranulocytosis
41. Partial opioid agonist - considered a strong analgesic - has a long duration of action and is resistant to naloxone reversal
inhibits Na+/K+/2Cl - cotransport
Angiotensin receptor
Cyanocobalamin (Vit B12)
Buprenorphine
42. Prolonged exposure to this inhaled anesthetic may lead to megaloblastic anemia
Nitrous oxide
Cytomel
Cholinesterase regenerators - pralidoxime
Pregnancy
43. Life threatening cardiac event that prolong QT leads to
Psychotic state - overdose causes agitation - restlessness - tachycardia - hyperthermia - hyperreflexia - and seizures
Torsades de pointes
Beta - blockers
Lithium
44. Opioids used in anesthesia
Morphine and fentanyl
Succinylcholine
Tolerance
Bleeding
45. Withdrawal from this drug causes lethargy - irritability - and headache
Peripheral neuropathy (also excessive alcohol use is associated with HTN - anemia - and MI)
Aplastic anemia and acute hepatic failure
Caffeine
Hot flashes
46. Produces both rapid anesthesia and recovery - has antiemetic activity and commonly used for outpatient surgery - may cause marked hypotension
Ethanol - fomepizole
Propofol
Erythropoietin
Chloramphenicol
47. Amphetamine agents
Naloxone (IV) - naltrexone (PO)
Ezetimibe (Zetia)
Dobutamine and dopamine
Dextroamphetamines and methamphetamine
48. Agent which stimulates cardiac contractile force more than rate with little effect on total peripheral resistance
Albuterol
Dobutamine
Physostigmine
Mifepristone
49. CCB contraindicated in CHF
Protease inhibitors
Skeletal muscle tremor - tachycardia
Verapamil
LSD
50. Approved for use in severe pulmonary HTN
St. Anthony's Fire
Prostaglandin E1 (misoprostol) PGE2 - and PGF2alpha
Ipratropium
PGI2 (epoprostenol)