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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Ability to produce less than 100% of the response






2. Irreversible - nonselective COX inhibitor






3. Antidepressant which is inhibitor of CYP450 enzymes and may be associated with hepatic failure






4. This may enhance activity of local anesthetics






5. Site of action of thiazide diuretics






6. Drug notorious for causing pseudomembranous colitis






7. Antidepressants with no effect on BP - no sedation






8. Concurrent use of fibrates and statins increases risk of






9. Aspirin reduces mortality in unstable angina by






10. Agent used to treat MI and to reduce incidence of subsequent MI






11. Newer NSAID that selectively inhibits COX-2






12. State of analgesia and amnesia produced when fentanyl is used with droperidol and nitrous oxide






13. DOC for herpes and its MOA






14. Inhaled anesthetic causes peripheral vasodilation






15. Toxicity of anticholinergics






16. Can be effective for short term therapy of thyroid storm - but after several weeks of therapy causes an exacerbation of hyperthyroidism






17. Drug causing depletion of substance P (vasodilator)






18. Reason benzos are used cautiously in pregnancy






19. Treatment for TB patients (think RIPE)






20. Toxicity of these agents include bradycardia - AV blockade - exacerbation of acute CHF; signs of hypoglycemia may be masked (tachycardia - tremor - and anxiety)






21. Anti - biotic frequently used for chronic UTI prophylaxis






22. MOA of class III antiarrhythmics






23. MOA of metformin






24. This agent has greater affinity for muscarinic receptors and used for postoperative and neurogenic ileus and urinary retention






25. Warfarin is contraindicated in






26. Common SE of tamoxifen and raloxifene






27. Local anesthetic with vasoconstrictive property - favored for head - neck - and pharyngeal surgery






28. Antiestrogen drugs used for fertility and breast cancer respectively






29. Agent having no effect on D2 receptors - blocks D4 - reserved for resistant schizophrenia - and can cause fatal agranulocytosis






30. Benzodiazepine used adjunctively in anesthesia






31. Anti - viral with a dose limiting toxicity of pancreatitis






32. 2nd generation antihistamines






33. One depolarizing blocker that causes continuous depolarization and results in muscle relaxation and paralysis - causes muscle pain postoperatively and myoglobinuria may occur






34. Selective Alpha -1A blocker - used for BPH - but with little effect on HTN






35. Selective estrogen receptor modulator (SERM) used for prevention of osteoporosis and prophylaxis in women with risk factors for breast cancer






36. SE of long term (>5 days) corticosteroid therapy and remedy






37. The most frequent cause of acute deaths in cholinesterase inhibitor toxicity






38. Epinephrine is often mixed with a local anesthetic to






39. Antidote used for heparin overdose






40. Bisphosphonates that cannot be used on continuous basis because it caused osteomalacia






41. Sedative - Hypnotics action






42. Peakless ling acting insulin






43. Alpha 1 agonist toxicity






44. Moderate opioid agonists






45. Drugs of choice for generalized tonic - clonic and partial seizures






46. Selective Alpha 2 blocker used for impotence (controversial effectiveness)






47. Reason ergot alkaloids are contraindicated in pregnancy






48. Thrombolytic used for acute MI and ischemic (non hemorrhagic) CVA






49. Drug used in ergot alkaloids overdose - ischemia and gangrene






50. These drugs strongly potentiate and prolong effect of neuromuscular blockade (NMB)