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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Antidote used for cyanide poisoning






2. DOC for digoxin induced arrhythmias






3. Enzyme that metabolizes acetaldehyde to acetate






4. Antibiotic causing red - man syndrome - and prevention






5. The most toxic organophosphate






6. Agents that inhibit acetaldehyde dehydrogenase






7. SE of CCB






8. Treatment of myasthenia gravis






9. Used intravenously for acute arrhythmias during surgery






10. Time it takes for amount of drug to fall to half of its value; this is a constant in first order kinetics (majority of drugs)






11. These beta blockers are less lipid soluble






12. Causes acne - premature closure of epiphyses - masculinization in females - hepatic dysfunction - MI - and increases in libido and aggression






13. Condition will result from in combination of MAOI with tyramine containing foods (ex. wine - cheese - and pickled meats)






14. Initial DMARD of choice for patients with RA






15. SE of phenytoin






16. Available bisphosphonates






17. Hormone inhibiting prolactin release






18. Prolonged exposure to this inhaled anesthetic may lead to megaloblastic anemia






19. Opioid used in the management of withdrawal states






20. Interaction with this drug requires dose reduction of 6- MP






21. Agent that inhibits alcohol dyhydrogenase and its clinical use






22. Combined alpha and beta blocking agents that may have application in treatment of CHF






23. B- blockers that are more cardioselective






24. Skeletal muscle agent that undergoes Hofmann elimination (breaks down spontaneously)






25. Reversal of blockade by neuromuscular blockers






26. Methyldopa is contraindicated in






27. Effective in preventing TIA's






28. Diuretics work in CHF by






29. Intermediate acting glucocorticoids






30. Rapid acting - crystalline zinc insulin used to reverse acute hyperglycemia






31. DOC for CMV retinitis






32. MOA of Leflunomide (newer agent)






33. SE of these drugs include dependence - withdrawal syndrome - sedation - euphoria - respiratory depression nausea and vomiting - constipation - biliary spasm - increased ureteral and bladder tone - and reduction in uterine tone






34. MOA of repaglinide






35. Warfarin is contraindicated in






36. Some cell cycle non - specific drugs






37. Antidote for hyperkalemia






38. Common side effect of Rifampin






39. Ergot alkaloid that is a partial agonist at D2 receptors in the brain - used for patients who are refractory or cannot tolerate levodopa - causes erythromelalgia






40. Specific pharmacokinetic characteristic of amiodarone






41. Common mechanism by which overdose result in death






42. Drug used supraventricular arrhythmias






43. Epinephrine is often mixed with a local anesthetic to






44. Antidepressant with MOA as alpha 2 antagonist - has effects on both 5- HT and NE - blocks histamine receptors - and is sedating






45. The most frequent cause of acute deaths in cholinesterase inhibitor toxicity






46. Class of anti - arrhythmics that has a pro - arrhythmic effect (CAST trial) - therefore are used as last line agents






47. Digoxin toxicity can be precipitated by






48. Somatotropin (GH) analog used in GH deficiency (dwarfism)






49. Anti - androgen used for prostate cancer






50. Drug of choice for myoclonic seizures