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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
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  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Drug used supraventricular arrhythmias






2. SE of colchicine






3. Usual time needed for full effect of antidepressant therapy






4. Methyldopa is contraindicated in






5. Reason fluoroquinolones are contraindicated in children and pregnancy






6. MOA of penicillin






7. DOC for giardia - bacterial vaginosis - pseudomembranous colitis - and trichomonas






8. Moderate opioid agonists






9. Phosphodiesterase inhibitors that increase mortality and have been found to have NO beneficial effects






10. Treatment for TB patients (think RIPE)






11. Clinical uses of these agents include treatment of HTN - angina - arrhythmias - chronic CHF - and selected post MI patients






12. H1 antagonist used in motion sickness






13. Target plasma concentration times (volume of distribution divided by bioavailability)






14. Incidence of hyoglycemia with metformin






15. All opioids except this agent (which has a muscarinic blocking action) cause pupillary constriction






16. Cause dizziness - tachycardia - hypotension - and flushing






17. Agent decreases the excitatory actions of cholinergic neurons. May improve tremor and rigidity but have LITTLE effect on bradykinesia. Atropine - like side effects






18. Anti - androgen used for prostate cancer






19. Major nutritional side effect of bile acid - binding resins






20. Endogenous substances commonly interpreted as histamine - serotonin - prostaglandins - and vasoactive peptides






21. MOA of nesiritide






22. Barbiturates MOA






23. GHRH analog used as diagnostic agent






24. Newer alpha 2 agonist (apraclonidine and brimonidine) treat glaucoma by acting to






25. Peptide drug used to treat CHF






26. Reason troglitazone was withdrawn from market






27. Laboratory value required to be monitored for patients on valproic acid

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28. Metronidazole SE if given with alcohol






29. SE of nesiritide






30. Cholinomimetics that increase outflow - open trabecular meshwork - and cause ciliary muscle contraction






31. SE of minoxidil






32. DMARDs are slow acting drugs for






33. The most frequent cause of acute deaths in cholinesterase inhibitor toxicity






34. SSRI indicated for premenstrual dysphoric disorder






35. Drugs of choice for absence seizures






36. Where are beta cells found in the pancreas?






37. PTU (propylthiouracil) MOA






38. These agents are CNS depressants






39. Beta blockers work in CHF by






40. Thrombolytic used for acute MI and ischemic (non hemorrhagic) CVA






41. Converts asparagine to aspartate and ammonia - denies cancer cells of essential AA (asparagine)






42. Antidote to reverse actions of heparin






43. Benzodiazepine receptor antagonist - it accelerates recovery from benzodiazepine overdose






44. Agent effective in physiologic and essential tremor






45. Common SE of spironolactone






46. Common mechanism by which overdose result in death






47. What do beta cells in the pancreas produce?






48. Irreversible - nonselective COX inhibitor






49. Limiting adverse effect of ganglion blockade that patients usually are unable to tolerate






50. Block cardiac adverse effects of thyrotoxicosis such as tachycardia - inhibits the conversion of T4 to T3