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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. The most important sign of withdrawal syndrome






2. Two toxicities of aminoglycosides






3. 1st generation antihistamine that is highly sedating






4. Agent used in drug therapy of Parkinson's instead of Dopamine which has low bioavailability and does not cross the BBB






5. Scabicide organophosphate






6. The most common type of drug interaction of sedative hypnotics with other depressant medications






7. NSAID also available as an ophthalmic preparation






8. Radio contrast media that inhibits the conversion of T4 to T3






9. T3 compound less widely used






10. MOA of Cardiac glycosides (eg. digoxin)






11. Antifungal agent used for inhibition of all gonadal and adrenal steroids






12. Pneumonic for beta receptors






13. Class of drugs with ability to decrease the maximal response to an agonist






14. MOA of class III antiarrhythmics






15. Nonselective alpha agonists that increases outflow - probably via the uveoscleral veins






16. Short acting glucocorticoids






17. Cause dizziness - tachycardia - hypotension - and flushing






18. Anticancer drug also used in RA - produces acrolein in urine that leads to hemorrhagic cystitis






19. Treatment of choice for organophosphate overdose






20. Usual time needed for full effect of antidepressant therapy






21. Agents may exacerbate tardive dyskinesias (may be irreversible and there is no treatment)






22. Mechanisms of action for Phenytoin - Carbamazepine - Lamotrigine






23. Muscarinic antagonist used in asthma






24. Somatotropin (GH) analog used in GH deficiency (dwarfism)






25. MOA of aspirin






26. Pneumonic for 3 zones of adrenal cortex






27. These agents are CNS depressants






28. SE of nitrates






29. Agent that is teratogen and causes a fetal syndrome






30. Anti - rheumatic agent also used for Chron's disease






31. Captopril and enalapril (- OPRIL ending) are






32. Non - benzodiazepine used as an anxiolytic






33. Drug that selectively inhibits COX 2






34. Chelating agent used in acute iron toxicity






35. Longer acting local anesthetics which are less dependent on vasoconstrictors






36. Median effective dose required for an effect in 50% of the population






37. Common SE of tamoxifen and raloxifene






38. Alpha agonist used to produce mydriasis and reduce conjunctival itching and congestion caused by irritation or allergy - it does not cause cycloplegia






39. Commonly abused LA which has cardiovascular toxicity including severe hypertension with cerebral hemorrhage - cardiac arrhythmias - and myocardial infarction






40. Anti - malarial drug used in rheumatoid arthritis (RA)






41. Antidote to benzodiazepine overdose (antagonist that reverses the CNS effects)






42. SE of Thiazolindinediones






43. DOC for digoxin induced arrhythmias






44. Atypical antipsychotic causing high prolactin levels






45. Drug used in Chagas disease






46. SelectiveB1 Receptor blockers that may be useful in treating patients even though they have asthma






47. ABVD regimen used for HD - but appears less likely to cause sterility and secondary malignancies than MOPP






48. Benzodiazepine that is used for anesthesia






49. Agents having active metabolites - long half lives - and a high incidence of adverse effects






50. TCA with greatest sedation of this group - and marked antimuscarinic effects - used for sleep