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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
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  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Antidote for salicylate intoxication






2. COX 2 inhibitors may have reduced risk of






3. Anti - rheumatic agent also used for Chron's disease






4. Heparin (PTT) increases activity of






5. Clinical use for H2 blockers






6. Most frequent route of metabolism






7. Interact with microtubules (but unlike vinca which prevent disassembly of tubules) - it stabilizes tubulin and cells remain frozen in metaphase






8. Anti - emetics used in association with anti - cancer drugs that are 5- HT3 (serotonin receptor subtype ) antagonists






9. Inhibitors of CYP450






10. Anti - seizure agent that exhibits non - linear metabolism - highly protein bound - causes fetal hydantoin syndrome - and stimulates hepatic metabolism






11. Aromatase inhibitor used in breast cancer






12. This diuretic decreases aqueous secretion due to lack of HCO3- ion. Causes drowsiness and paresthesias - alkalinization of the urine may precipitate calcium salts - hypokalemia - acidosis






13. Tolerance to all effects of opioid agonists can develop except






14. DOC for febrile seizures






15. Causes bone marrow suppression






16. Benzodiazepine that has efficacy against absence seizures and in anxiety states - such as agoraphobia






17. Anti - seizure agent that induces formation of liver drug - metabolism enzymes - is teratogen and can cause craniofacial anomalies and spina bifida






18. Anti - androgen used for hirsutism in females






19. The selective agents loose their selectivity at






20. Arterial vasodilator that works by opening K+ channels






21. Triptan available in parenteral and nasal formulation






22. The ratio of the rate of elimination of a drug to its plasma concentration






23. Chelating agent used in acute iron toxicity






24. DOC for influenza A






25. Antidote used for heparin overdose






26. SE of thiazide (HCTZ) diuretics






27. Window between therapeutic effect and toxic effect






28. Examples of alpha - glucosidase inhibitors (AGI)






29. Agent to treat hypochromic microcytic anemias






30. Agent for pernicious anemia






31. Analog of hypoxanthine - needs HGPRTase for activation






32. The most common type of drug interaction of sedative hypnotics with other depressant medications






33. Methyldopa is contraindicated in






34. Alpha 1 agonist toxicity






35. Only direct acting agent that is very lipid soluble and used in glaucoma






36. A1a - selective blocker with no effects on HTN used for BPH






37. Antidote useful for some drug induced Torsade de pointes






38. Antidote for thrombolytics






39. Longer acting local anesthetics which are less dependent on vasoconstrictors






40. Available bisphosphonates






41. Drug ofter used in combination with TNF - alpha inhitors for RA






42. NSAID also available as an ophthalmic preparation






43. MOA of class I A (eg. Procainamide) - class IB (eg. Lidocaine) - and class IC (eg. Flecainide) antiarrhythmics






44. Antidepressant which is inhibitor of CYP450 enzymes and may be associated with hepatic failure






45. What do delta cells in the pancreas produce?






46. Agent that is the antidote for methanol overdose






47. Pneumonic for beta receptors






48. These LA's have surface activity






49. Toxicity of anticholinergics






50. Cheap wide spectrum antibiotic DOC for otitis media







Sorry!:) No result found.

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