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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Barbiturates may precipitate this hematologic condition






2. Agent used in drug therapy of Parkinson's instead of Dopamine which has low bioavailability and does not cross the BBB






3. Triptan available in parenteral and nasal formulation






4. Antidote used for tricyclic antidepressants (TCA)






5. Antiplatelet drug reserved for patients allergic to aspirin






6. The selective agents loose their selectivity at






7. Nitrate used for acute anginal attacks






8. Toxicity of amphotericin






9. DOC for malignant hyperthermia that may be caused by use of halogenated anesthetics






10. Converts asparagine to aspartate and ammonia - denies cancer cells of essential AA (asparagine)






11. These agents are CNS depressants






12. SE for Felbamate






13. Cephalosporins Not able to cross the BBB






14. Reduced seizure threshold






15. Examples of alpha - glucosidase inhibitors (AGI)






16. Cutaneous flush and be reduced by pretreatment with






17. SE of acetazolamide






18. 2nd generation antihistamines






19. Commonly abused LA which has cardiovascular toxicity including severe hypertension with cerebral hemorrhage - cardiac arrhythmias - and myocardial infarction






20. Agent effective in physiologic and essential tremor






21. Patients being treated with lithium - who are dehydrated - or taking diuretics concurrently - could develop






22. H2 blocker that causes the most interactions with other drugs






23. MOA of thiazolindinediones






24. Side effects seen with tricyclic antidepressants






25. SE of spironolactone






26. Nonselective alpha - blocking drug - short acting and reversible - used for rebound HTN from rapid clonidine withdrawal - and Raynaud's phenomena






27. Non - depolarizing skeletal muscle antagonist that has short duration






28. MOA for Ethosuximide






29. Newer atypical antipsychotic used for bipolar disorder - known to cause weight gain - and adversely affect diabetes






30. Phosphodiesterase inhibitors that increase mortality and have been found to have NO beneficial effects






31. Treatment of atropine overdose and glaucoma (because lipid soluable). Enters the CNS rapidly and has a stimulant effect - which may lead to convulsions






32. DOC for febrile seizures






33. Anticancer drug also used in RA - produces acrolein in urine that leads to hemorrhagic cystitis






34. Aspirin reduces mortality in unstable angina by






35. Fibrates (gemfibrozil) increase activity of






36. Sympathetic agent which stimulates heart rate and can dilate vessels in skeletal muscle at low doses






37. Cystitis - postoperative bladder spasms - or incontinence






38. Treatments available for nicotine addiction






39. Anti - thyroid drugs






40. Cholinomimetics that increase outflow - open trabecular meshwork - and cause ciliary muscle contraction






41. Agents that reduce heart rate - contractility - and O2 demand






42. Syndrome of hypersecretion of gastric acid and pepsin usually caused by gastrinoma; it is associated with severe peptic ulceration and diarrhea






43. This beta blocker is highly lipid soluble and may account for side effects such as nightmares






44. First generation sulfonylurea






45. Drug that causes gray baby syndrome and aplastic anemia






46. Inhibitors of CYP450






47. SE for ganciclovir






48. SE of tPA






49. Chelating agent used in Wilson's disease






50. Antidote used for organophosphate/anticholinesterase poisoning