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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. One depolarizing blocker that causes continuous depolarization and results in muscle relaxation and paralysis - causes muscle pain postoperatively and myoglobinuria may occur






2. Where are beta cells found in the pancreas?






3. Most important toxic effects of most local anesthetics






4. The fraction of administered dose of a drug that reaches systemic circulation






5. Very rapid acting insulin - having fastest onset and shortest duration of action






6. Long acting glucocorticoids






7. Selective Alpha 1 blocker used for hypertension - BPH - may cause first dose orthostatic hypotension






8. Indirect - Acting ACh Agonist - alcohol - short DOA and used in diagnosis of myasthenia gravis






9. Generation of antihistamine that has the most CNS effects






10. DMARDs are slow acting drugs for






11. Losartan and valsartan block






12. Activation of these receptors open K+ ion channels to cause membrane hyperpolarization






13. MOA of erythromycin






14. Agent for pernicious anemia






15. SE of OCs






16. Prototypical drug is atropine






17. Antidote for arsenic - mercury - lead - and gold poisoning






18. Antidote used for iron salt toxicity






19. Agent used for acute muscle spasm






20. Relates the amount of drug in the body to the plasma concentration






21. B- blockers that are more cardioselective






22. Weak opioid agonist - poor analgesic - its overdose can cause severe toxicity including respiratory depression - circulatory collapse - pulmonary edema - and seizures






23. Most common side effect of 1st generation antihistamines






24. Pungent inhaled anesthetic which leads to high incidence of coughing and vasospasm






25. Beta 2 agonist toxicity






26. Inhibitors of CYP450






27. SE of loop (furosemide) diuretics






28. Benzodiazepine with useful relaxant effects in skeletal muscle spasticity of central origin






29. Non ergot agents used as first - line therapy in the initial management of Parkinson's






30. Inhibitors of catechol - O- methyltransferase (COMT) - used as adjuncts in Parkinson's dx and cause acute hepatic failure (monitor LFT's)






31. MOA of repaglinide






32. SE of phenytoin






33. Ability to bind reversibly to the same site as the drug and without activating the effector system






34. Interaction with this drug requires dose reduction of 6- MP






35. Agent that is a partial agonist for the 5- HT1A receptor






36. Specific pharmacokinetic characteristic of amiodarone






37. Inversely related to potency of anesthetics






38. Aspirin is contraindicated in children with viral infection

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39. Peakless ling acting insulin






40. Beta 1 agonists used in acute CHF






41. Peptide drug used to treat CHF






42. Major drug interaction with Quinidine






43. Inhibitor of leukotrienes (LTD4) receptors and used in asthma






44. Drug used for MRSA






45. Antidepressant inhibiting norepinephrine - serotonin - and dopamine reuptake






46. Incidence of hyoglycemia with metformin






47. Potassium sparing diuretics inhibit






48. Inhibit angiotensin - converting enzyme (ACE)






49. SE of minoxidil






50. GnRH agonist used for infertility or different types of CA depending on pulsatile or steady usage respectively