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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Except for these agents all SSRI have significant inhibition of CytP450 enzymes






2. Biguanide






3. DOC for paroxysmal supraventricular tachycardia; has high efficacy and short duration of action






4. Block cardiac adverse effects of thyrotoxicosis such as tachycardia - inhibits the conversion of T4 to T3






5. Mineralocorticoids






6. Nitrate used for acute anginal attacks






7. Inhibits conversion of cholesterol to pregnenolone therefore inhibiting corticosteroid synthesis






8. Antidote for tissue plasminogen activator (t - PA) - streptokinase






9. Treatment of motion sickness






10. Agent decreases the excitatory actions of cholinergic neurons. May improve tremor and rigidity but have LITTLE effect on bradykinesia. Atropine - like side effects






11. Agents that reduce heart rate - contractility - and O2 demand






12. Chemical antagonists that bind to the inhibitor of ACh Estrace and displace the enzyme (if aging has not occurred)






13. GnRH antagonist with more immediate effects - used for infertility






14. Antidote used for acetaminophen (APAP) toxicity






15. Structurally related to acetylcholine - used to produce muscle paralysis in order to facilitate surgery or artifical ventilation. Full doses lead to respiratory paralysis and require ventilation






16. Initial DMARD of choice for patients with RA






17. Anti - seizure medication also used in the prevention of migraines






18. Pneumonic for beta receptors






19. DMARDs are slow acting drugs for






20. Similar to clonidine and may cause hypotension






21. Antiplatelet drug reserved for patients allergic to aspirin






22. Class of drugs with ability to decrease the maximal response to an agonist






23. SE of OCs






24. Diuretics work in CHF by






25. Acetaminophen only has






26. SE of Amiodarone






27. Limiting side effect of Quinidine






28. Drug ofter used in combination with TNF - alpha inhitors for RA






29. Concentration in the plasma times (clearance divided by bioavailability)






30. Chelating agent used in acute iron toxicity






31. SE of both warfarin and heparin






32. Three C's associated with TCA toxicity






33. Arterial vasodilator that works by opening K+ channels






34. Major nutritional side effect of bile acid - binding resins






35. THC is active ingredient - SE's include impairment of judgment - and reflexes - decreases in blood pressure and psychomotor performance occur






36. Other side effects of Quinidine






37. Important in synthesis of glucose to glycogen in the liver






38. Drug used for African sleeping sickness






39. Anti - arrhythmic with 15 second duration of action






40. Relates the amount of drug in the body to the plasma concentration






41. Amphetamine agents






42. Drug increases the renal clearance hence decreases levels of lithium






43. Distribution of histamine receptors H1 - H2 - and H3






44. Prevention of cyclophosphamide induced hemorrhagic cystitis






45. Facilitates GABA presynaptic inhibition






46. State of analgesia and amnesia produced when fentanyl is used with droperidol and nitrous oxide






47. MOA of thiazide diuretics






48. Ability to bind reversibly to the same site as the drug and without activating the effector system






49. Thrombolytic that can cause allergic reaction






50. MOA of colchicine (used in acute gout)