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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Sympathetic agent which stimulates heart rate and can dilate vessels in skeletal muscle at low doses






2. Class of drugs with ability to decrease the maximal response to an agonist






3. What do alpha cells in the pancreas produce?






4. Cholestyramine and colestipol are






5. Contraindications to use of atropine






6. Agent that is metabolized to acetaldehyde by alcohol dehydrogenase and microsomal ethanol - oxidizing system (MEOS)






7. Agent used for acute muscle spasm






8. Initial DMARD of choice for patients with RA






9. DOC for RSV






10. Meglitinide class of drugs






11. Drug that inhibits alcohol dehydrogenase and is used in ethylene glycol exposure






12. Non - depolarizing skeletal muscle antagonist that has short duration






13. Antidote to reverse actions of heparin






14. Heparin (PTT) increases activity of






15. Lethal arrhythmias resulting from concurrent therapy with azole fungals (metabolized by CYP 3A4) and these antihistamines which inhibit the 3A4 iso - enzyme.






16. DOC for digoxin induced arrhythmias






17. Moderate opioid agonists






18. Digoxin toxicity can be precipitated by






19. Antivirals associated with neutropenia






20. SE of nitrates






21. Anti - Parkinson's drug which increases intraocular pressure and is contraindicated in closed angle glaucoma






22. DOC for paroxysmal supraventricular tachycardia; has high efficacy and short duration of action






23. MOA of local anesthetics (LA's)






24. THC is active ingredient - SE's include impairment of judgment - and reflexes - decreases in blood pressure and psychomotor performance occur






25. MOA of class III antiarrhythmics






26. Almost all local anesthetics have this property and sometimes require the administration of vasoconstrictors (ex. Epinephrine) to prolong activity






27. Long acting sympathomimetic - sometimes used to improve urinary continence in children and elderly with enuresis






28. Anti - arrhythmics that decrease mortality






29. Direct vasodilator of arteriolar smooth muscle






30. Three C's associated with TCA toxicity






31. Hyperglycemic agent that increases cAMP and results in glycogenolysis - gluconeogenesis - reverses hypoglycemia - also used to reverse severe beta - blocker overdose and smooth muscle relaxation






32. Approved for use in severe pulmonary HTN






33. Agents having higher sedation and antimuscarinic effects than other TCA's






34. Drug increases the renal clearance hence decreases levels of lithium






35. Another pneumonic for anticholinergic toxicity


36. Anticancer drug also used in RA - produces acrolein in urine that leads to hemorrhagic cystitis






37. NSAID available orally - IM and ophthalmically






38. Vancomycin MOA






39. Drugs used in the management of angina






40. Laboratory value required to be monitored for patients on valproic acid


41. The most toxic organophosphate






42. Time it takes for amount of drug to fall to half of its value; this is a constant in first order kinetics (majority of drugs)






43. Amino acid derivative - active as an insulin secretagogue






44. DOC for CMV retinitis






45. Methylxanthine derivative used as a remedy for intermittent claudication






46. Some cell cycle non - specific drugs






47. Fibrates (gemfibrozil) increase activity of






48. Inhibit synaptic activity of primary afferents and spinal cord pain transmission neurons






49. When the rate of drug input equals the rate of drug elimination






50. Regimen used for non - Hodgkin's lymphoma