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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. DOC for giardia - bacterial vaginosis - pseudomembranous colitis - and trichomonas






2. Proteins that prevent action of tumor necrosis factor alpha (TNF- alpha)






3. Direct vasodilator of arteriolar smooth muscle






4. All antidepressants have roughly the same efficacy in treating depression - agents are chosen based on these criterion






5. Another pneumonic for anticholinergic toxicity

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6. Beta 2 agonist toxicity






7. SE for Felbamate






8. SE of phenytoin






9. Ultra long acting insulin - has over a day duration of action






10. Antihistamine that can be used for anxiety and insomnia and is not addictive






11. Drug notorious for causing pseudomembranous colitis






12. DOC for tx of pseudomembranous colitis






13. Agents for reduction of postpartum bleeding






14. Very rapid acting insulin - having fastest onset and shortest duration of action






15. All opioids except this agent (which has a muscarinic blocking action) cause pupillary constriction






16. Drug that causes contraction of the uterus






17. Class of drugs that reversibly inhibit COX






18. PCN active against pseudomonas






19. Treatment of resistant pseudomembranous colitis






20. These prevent the action of Ach at the skeletal muscle endplate to produce a 'surmountable blockade -' effect is reversed by cholinesterase inhibitors (ex. neostigmine or pyridostigmine)






21. Important in synthesis of glucose to glycogen in the liver






22. Fibrates (gemfibrozil) increase activity of






23. DOC for influenza A






24. Antiplatelet drug reserved for patients allergic to aspirin






25. Major effect of benzodiazepines on sleep at high doses






26. 2nd generation antihistamines






27. These agents are used as antidiarrheal






28. SE of INH






29. Interact with microtubules (but unlike vinca which prevent disassembly of tubules) - it stabilizes tubulin and cells remain frozen in metaphase






30. SSRI less likely to cause a withdrawal syndrome






31. Toxicity of amphotericin






32. Benzodiazepine with useful relaxant effects in skeletal muscle spasticity of central origin






33. Hyperglycemic agent that increases cAMP and results in glycogenolysis - gluconeogenesis - reverses hypoglycemia - also used to reverse severe beta - blocker overdose and smooth muscle relaxation






34. Anti - emetics used in association with anti - cancer drugs that are 5- HT3 (serotonin receptor subtype ) antagonists






35. Route of administration of warfarin






36. Receptors for serotonin (5HT-1) are located






37. DOC to treat chemo - induced nausea and vomiting






38. NSAID contraindicated in gout






39. Pungent inhaled anesthetic which leads to high incidence of coughing and vasospasm






40. Agent that is the antidote for methanol overdose






41. System that increases in activity with chronic ethanol exposure and may contribute to tolerance






42. Blows DNA (breaks DNA strands) - limiting SE is pulmonary fibrosis






43. Some cell cycle specific anti - cancer drugs






44. This parenteral beta blocker is a short acting (minutes)






45. GHRH analog used as diagnostic agent






46. ABVD regimen used for HD - but appears less likely to cause sterility and secondary malignancies than MOPP






47. Limiting adverse effect of ganglion blockade that patients usually are unable to tolerate






48. Anti - estrogen used for estrogen receptor + breast cancer






49. Inhibitor of lipoxygenase






50. Antipsychotic having the weakest autonomic effects