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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. MOA of class I A (eg. Procainamide) - class IB (eg. Lidocaine) - and class IC (eg. Flecainide) antiarrhythmics






2. SSRI indicated for premenstrual dysphoric disorder






3. Antidote used for cyanide poisoning






4. Distribution of histamine receptors H1 - H2 - and H3






5. MOA of drug or foods (grapefruit juice) that increase statin effect






6. Treatment of withdrawal syndrome involves






7. Anticoagulant of choice in pregnancy






8. Orthostatic hypotension and QT prolongation






9. SE of hydroxychloroquine






10. Withdrawal from this drug causes lethargy - irritability - and headache






11. THC is active ingredient - SE's include impairment of judgment - and reflexes - decreases in blood pressure and psychomotor performance occur






12. MOA of Bisphosphonates






13. Agents that inhibit acetaldehyde dehydrogenase






14. Major effect of benzodiazepines on sleep at high doses






15. Pneumonic for 3 zones of adrenal cortex






16. Endogenous substances commonly interpreted as histamine - serotonin - prostaglandins - and vasoactive peptides






17. B- blockers that are more cardioselective






18. SE of salicylates






19. Pyrimidine analog that causes 'Thymine - less death' given with leucovorin rescue






20. The most common type of drug interaction of sedative hypnotics with other depressant medications






21. Pungent inhaled anesthetic which leads to high incidence of coughing and vasospasm






22. Drug that inhibits alcohol dehydrogenase and is used in ethylene glycol exposure






23. Agent used in drug therapy of Parkinson's instead of Dopamine which has low bioavailability and does not cross the BBB






24. Second generation sulfonylurea






25. Agent that is the antidote for methanol overdose






26. Used for Cushing's syndrome (increased corticosteroid)






27. Most frequent route of metabolism






28. Antidote used for organophosphate/anticholinesterase poisoning






29. Acetaminophen only has






30. Nitrate used to prevent further attacks






31. Anti - seizure drugs used as alternative drugs for mood stabilization






32. SE of Aspirin






33. Agent that is teratogen and causes a fetal syndrome






34. These agents are used as antidiarrheal






35. 5 alpha - reductase inhibitor used for benign prostatic hyperplasia (BPH) and male pattern baldness






36. DOC for influenza A






37. Agent used for closure of patent ductus arteriosus






38. The ratio of the rate of elimination of a drug to its plasma concentration






39. Treatment of myasthenia gravis






40. Disease caused by excess ergot alkaloids

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41. Routes of administration of heparin






42. Inhibitors of CYP450






43. Drug ofter used in combination with TNF - alpha inhitors for RA






44. The most common neurologic abnormality in chronic alcoholics






45. System that increases in activity with chronic ethanol exposure and may contribute to tolerance






46. Some cell cycle specific anti - cancer drugs






47. SE of OCs






48. Local anesthetic with vasoconstrictive property - favored for head - neck - and pharyngeal surgery






49. Newer estrogen receptor antagonist used in advanced breast cancer






50. Alpha agonist used to produce mydriasis and reduce conjunctival itching and congestion caused by irritation or allergy - it does not cause cycloplegia