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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. HIV med used to reduce transmission during birth






2. Heterocyclic antidepressants least likely to affect sexual performance - used for management of nicotine withdrawal - SE's include dizziness - dry mouth - aggravation of psychosis - and seizures






3. Analog of hypoxanthine - needs HGPRTase for activation






4. Treatment of choice for organophosphate overdose






5. Antidote useful for some drug induced Torsade de pointes






6. Local anesthetic with vasoconstrictive property - favored for head - neck - and pharyngeal surgery






7. Only phenothiazine not exerting antiemetic effects - can cause visual impairment due to retinal deposits - and high doses have been associated with ventricular arrhythmias






8. Route of administration of warfarin






9. Converts asparagine to aspartate and ammonia - denies cancer cells of essential AA (asparagine)






10. Antidote to reverse actions of warfarin






11. Treat manifestations of Parkinson's disease and EPS






12. This beta blocker is the longest acting






13. SE of alpha blockers






14. All opioids except this agent (which has a muscarinic blocking action) cause pupillary constriction






15. Cause dizziness - tachycardia - hypotension - and flushing






16. Most common SE of fibrates






17. GnRH agonist used for infertility or different types of CA depending on pulsatile or steady usage respectively






18. Agent used neutropenia especially after chemotherapy






19. Drug notorious for causing pseudomembranous colitis






20. MOA and effect of nitric oxide






21. MOA of Cardiac glycosides (eg. digoxin)






22. Hormone inhibiting prolactin release






23. CCB are DOC for

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24. Beta 2 agonist toxicity






25. Adenosine's MOA






26. SE of tPA






27. DOC for paroxysmal supraventricular tachycardia (PSVT)






28. Antidote used for beta agonist toxicity (eg. Metaproterenol)






29. Alpha 1selective blockers






30. Alpha 1 agonist toxicity






31. Prostaglandins that cause abortions






32. Agent effective in physiologic and essential tremor






33. Inhaled anesthetic with a low blood/gas partition coefficient






34. Methylxanthine derivative used as a remedy for intermittent claudication






35. Vitamins containing iron should Not be taken simultaneously with levothyroxine because






36. GHRH analog used as diagnostic agent






37. SE of phenytoin






38. DOC for status epilepticus






39. Causes bone marrow suppression






40. MOA of nitrates






41. H2 blocker that causes the most interactions with other drugs






42. Tubocurarine is the prototype - pancuronium - atracurium - vecuronium are newer short acting agent - produce competitive block at end plate nicotinic receptor - causing flaccid paralysis






43. Neurotoxicity with isoniazid (INH) prevented by






44. Reduced seizure threshold






45. Term for a narrow margin of safety






46. 1st generation antihistamine that is least sedating






47. MOA for Ethosuximide






48. MOA of nateglinide






49. Anti - psychotics available in depot preparation






50. These agents increase cardiac output and may be beneficial in treatment of acute heart failure and some types of shock