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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. MOA of local anesthetics (LA's)






2. DOC for paroxysmal supraventricular tachycardia (PSVT)






3. Beta 1 agonists used in acute CHF






4. Penicillins active against penicillinase secreting bacteria






5. Mast cells to reduce release of hisamine and inflammatory mediators






6. MOA of quinolones






7. DOC for management of acute ventricular arrhythmias






8. Antiarrhythmic effective in most types of arrhythmia






9. Difference between aspirin and other NSAIDS






10. SE of HMG COA reductase inhibitors






11. Beta 1 agonist toxicity






12. Non - depolarizing skeletal muscle antagonist that has short duration






13. Organophosphate anthelmintic agent with long DOA






14. Barbiturates decrease the effectiveness of many other drugs via this pharmacokinetics property






15. Diuretic used to antagonize aldosterone receptors






16. These agents are used as antidiarrheal






17. 5 alpha - reductase inhibitor used for benign prostatic hyperplasia (BPH) and male pattern baldness






18. Irreversible - nonselective COX inhibitor






19. This is combined with L- dopa - inhibits DOPA decarboxylase (active only peripherally) which allows lower effective doses of L- dopa and allows for fewer SE's (GI distress - postural hypotension - and dyskinesias)






20. Some of SSRIs' therapeutic effects beside depression






21. Used intranasally and decreases bone resorption






22. This may enhance activity of local anesthetics






23. MOA of loop diuretics






24. Different steps of Phase I






25. Scabicide organophosphate






26. During Phase I these agents worsen muscle paralysis by succinylcholine - but during phase II they reverse the blockade produced by succinylcholine






27. Plasma concentration of a drug at a given time






28. Antidote for beta - blockers and hypoglycemia






29. Term for a narrow margin of safety






30. Only phenothiazine not exerting antiemetic effects - can cause visual impairment due to retinal deposits - and high doses have been associated with ventricular arrhythmias






31. DOC for status epilepticus






32. Interferes with activity of T- lymphocytes






33. Occurs when sedative hypnotics are used chronically or at high doses






34. Benzodiazepine that undergo extrahepatic conjugation (which are useful in older or hepatically impaired)






35. What do beta cells in the pancreas produce?






36. MOA of erythromycin






37. Benzodiazepine with useful relaxant effects in skeletal muscle spasticity of central origin






38. CCB are DOC for

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39. This produces 'dissociative anesthesia' - is a cardiovascular stimulant which may increases intracranial pressure - and hallucinations occur during recovery






40. This beta blocker is highly lipid soluble and may account for side effects such as nightmares






41. SE of clonidine






42. Heterocyclic antidepressants least likely to affect sexual performance - used for management of nicotine withdrawal - SE's include dizziness - dry mouth - aggravation of psychosis - and seizures






43. Anti - emetics used in association with anti - cancer drugs that are 5- HT3 (serotonin receptor subtype ) antagonists






44. Toxicities include nephrotoxicity and ototoxicity - leading to a severe interaction with aminoglycosides






45. Agent that is the antidote for methanol overdose






46. Anti - seizure drugs used as alternative drugs for mood stabilization






47. Selective alpha agonists that decreases aqueous secretion






48. Inhaled anesthetic with a low blood/gas partition coefficient






49. DOC for giardia - bacterial vaginosis - pseudomembranous colitis - and trichomonas






50. The most important sign of withdrawal syndrome