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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Used in pediatrics to maintain patency of ductus arteriosis






2. Product of proinsulin cleavage used to assess insulin abuse






3. Alpha agonist used to produce mydriasis and reduce conjunctival itching and congestion caused by irritation or allergy - it does not cause cycloplegia






4. Benzodiazepine that has efficacy against absence seizures and in anxiety states - such as agoraphobia






5. Inhibitor of leukotrienes (LTD4) receptors and used in asthma






6. Use of this opioid with MAOI can lead to hyperpyrexic coma - and with SSRI's can lead to serotonin syndrome






7. DOC for tx of pseudomembranous colitis






8. Two toxicities of aminoglycosides






9. Major SE of zileuton






10. Meningitis prophylaxis in exposed patients






11. Most important potential SE of metformin






12. Antivirals associated with neutropenia






13. Inhibitor of lipoxygenase






14. Ability of a drug to produce 100% of the maximum response regardless of the potency






15. MOA of nystatin






16. Common toxicities of cisplatin






17. Antidote used for benzodiazepine toxicity






18. Drug that selectively inhibits COX 2






19. Dose which is lethal to 50% of the population






20. Agents for reduction of postpartum bleeding






21. Agents used in Huntington's Disease






22. Primary endogenous substrate for Nitric Oxidase Synthase






23. Agent that inhibits hepatic metabolism - is hepatotoxic and teratogen that can cause neural tube defects and gastrointestinal distress






24. Antipsychotic used in the treatment of psychiatric symptoms in patients with dementia






25. 'Date rape drug'






26. Difference between COX 1 and COX 2






27. SE of nesiritide






28. Antidote used for warfarin toxicity






29. Inhibit angiotensin - converting enzyme (ACE)






30. What do beta cells in the pancreas produce?






31. Nitrosoureas with high lipophilicity - used for brain tumors






32. Dose may need to be increased during pregnancy or with Ocs due to increased TBG in plasma






33. Drug increases the renal clearance hence decreases levels of lithium






34. SE of INH






35. Shock due to septicemia or myocardial infarction is made worse by






36. MOA of nateglinide






37. SE of phenytoin






38. DOC for RSV






39. Inversely related to potency of anesthetics






40. Prostaglandins that cause abortions






41. MOA of repaglinide






42. Non - selective Beta - blocker also used for migraine prophylaxis






43. Window between therapeutic effect and toxic effect






44. Oral antibiotic of choice for moderate inflammatory acne






45. Penicillins active against penicillinase secreting bacteria






46. Drugs decrease intestinal absorption of cholesterol






47. Fluoride released by metabolism of this inhaled anesthetic may cause renal insufficiency






48. Tolerance to all effects of opioid agonists can develop except






49. This agent used to treat dry mouth in Sj






50. Toxic effect of anticancer drug can be lessened by rescue agents