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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Cheap wide spectrum antibiotic DOC for otitis media






2. Non ergot agents used as first - line therapy in the initial management of Parkinson's






3. These agents are CNS depressants






4. New class of drugs that works by inhibiting absorption of intestinal cholesterol and can be given concurrently with the Statins






5. Agent similar to cisplatin - less nephrotoxic - but greater myelosuppression






6. MOA of local anesthetics (LA's)






7. SE of nesiritide






8. Leads to respiratory depression progressing to coma and death






9. Antidote for hyperkalemia






10. DOC for malignant hyperthermia that may be caused by use of halogenated anesthetics






11. Treatment for opioid addiction






12. Nonselective alpha agonists that increases outflow - probably via the uveoscleral veins






13. Antidote used for cyanide poisoning






14. Anti - seizure drugs used also for pain of neuropathic orgin






15. Median toxic dose required for a toxic effect in 50% of the population






16. Window between therapeutic effect and toxic effect






17. Antihistamine that can be used for anxiety and insomnia and is not addictive






18. Cephalosporins able to cross the BBB






19. Alpha 1 agonist toxicity






20. This agent regenerates active cholinesterase and is a chemical antagonist used to treat organophosphate exposure






21. Dopamine agonist used in hyperprolactinemia






22. Used for Cushing's syndrome (increased corticosteroid)






23. Benzodiazepine that is used for anesthesia






24. 5 alpha - reductase inhibitor used for benign prostatic hyperplasia (BPH) and male pattern baldness






25. Arterial vasodilator that works by opening K+ channels






26. Antivirals associated with neutropenia






27. Losartan and valsartan block






28. Inhibitors of CYP450






29. Captopril and enalapril (- OPRIL ending) are






30. Use of this opioid with MAOI can lead to hyperpyrexic coma - and with SSRI's can lead to serotonin syndrome






31. Regimen used for breast cancer






32. Prototype antagonist of H1 and H2 receptors






33. Skeletal muscle agent that undergoes Hofmann elimination (breaks down spontaneously)






34. Benzodiazepines used to promote sleep






35. Penicillins active against penicillinase secreting bacteria






36. These agents are used as antidiarrheal






37. Converted to more active form DHT by 5 alpha - reductase






38. Increased risk of developing cataracts






39. Opioid that can be given PO - by epidural - and IV - which helps to relieve the dyspnea of pulmonary edema






40. Produce mydriasis and cycloplegia






41. Moderate opioid agonists






42. MOA of thiazide diuretics






43. SE of long term (>5 days) corticosteroid therapy and remedy






44. MOA for Valproic acid at high doses






45. MOA of quinolones






46. Other side effects of Quinidine






47. Drug used supraventricular arrhythmias






48. Inhibitors of catechol - O- methyltransferase (COMT) - used as adjuncts in Parkinson's dx and cause acute hepatic failure (monitor LFT's)






49. Fibrates are contraindicated in






50. Indirect - Acting ACh Agonist - alcohol - short DOA and used in diagnosis of myasthenia gravis