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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
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  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Non - steroidal estrogen agonist causes clear cell adenocarcinoma of the vagina in daughters of women who used it during pregnancy






2. H1 antagonist used in motion sickness






3. Activation of these receptors open K+ ion channels to cause membrane hyperpolarization






4. Limiting adverse effect of ganglion blockade that patients usually are unable to tolerate






5. Facilitates GABA presynaptic inhibition






6. Use of this opioid with MAOI can lead to hyperpyrexic coma - and with SSRI's can lead to serotonin syndrome






7. Class II antiarrhythmics are






8. Newer alpha 2 agonist (apraclonidine and brimonidine) treat glaucoma by acting to






9. MOA of neuroleptics






10. MOA of penicillin






11. Life threatening cardiac event that prolong QT leads to






12. Well - tolerated and are first - line antidepressants

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13. Antiplatelet drug reserved for patients allergic to aspirin






14. Antidote for tissue plasminogen activator (t - PA) - streptokinase






15. ADH agonist used for pituitary diabetes insipidus






16. Antidote to benzodiazepine overdose (antagonist that reverses the CNS effects)






17. Anti - viral agents associated with Stephen Johnson syndrome






18. Anti - psychotics available in depot preparation






19. Usual time needed for full effect of antidepressant therapy






20. Tolerance is marked and abstinence syndrome occurs






21. Barbiturates may precipitate this hematologic condition






22. Side effects seen with tricyclic antidepressants






23. The selective agents loose their selectivity at






24. Produce mydriasis and cycloplegia






25. Agent used to treat MI and to reduce incidence of subsequent MI






26. Antidote for digoxin toxicity






27. SE of lithium






28. Class of drugs that reversibly inhibit COX






29. Regimen used for breast cancer






30. Warfarin is contraindicated in






31. MOA for benzodiazepines and barbiturates






32. Toxic to the liver - kidney - lungs - bone marrow - peripheral nerves - and cause brain damage in animals - sudden death has occurred following inhalation






33. Toxicity caused by nitroprusside and treatment






34. Neurologic SE of benzodiazepines






35. DOC for herpes and its MOA






36. SE of methyldopa

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37. Topical DOC in impetigo






38. This beta blocker is the longest acting






39. Opioid available trans - dermally






40. Activation of these receptors close Ca2+ ion channels to inhibit neurotransmitter release






41. This beta blocker is highly lipid soluble and may account for side effects such as nightmares






42. Agent effective in physiologic and essential tremor






43. MOA of Leflunomide (newer agent)






44. Similar to clonidine and may cause hypotension






45. Long acting insulin






46. Digoxin is used in






47. Peptide drug used to treat CHF






48. Agent used in CHF that is a selective alpha and nonselective beta blocker






49. MOA and effect of nitric oxide






50. Agent more frequently associated with extrapyramidal side effects that can be treated with benzodiazepine - diphenhydramine or muscarinic blocker







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