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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
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  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Class of anti - arrhythmics that has a pro - arrhythmic effect (CAST trial) - therefore are used as last line agents






2. Longer acting benzodiazepines used in the management of withdrawal states of alcohol and other drugs






3. Partial opioid agonist - considered a strong analgesic - has a long duration of action and is resistant to naloxone reversal






4. Occurs when sedative hypnotics are used chronically or at high doses






5. MOA of penicillin






6. SE of penicillamine






7. Inhaled anesthetic - less likely to lower blood pressure than other agents - and has the smallest effect on respiration






8. Selective Alpha 1 blocker used for hypertension - BPH - may cause first dose orthostatic hypotension






9. Major effect of benzodiazepines on sleep at high doses






10. Chemical antagonists that bind to the inhibitor of ACh Estrace and displace the enzyme (if aging has not occurred)






11. Benzodiazepines that are the most effective in the treatment of panic disorder






12. Antivirals that are teratogens






13. This agent cause increased aqueous outflow






14. Antidote used for lead poisoning






15. GnRH antagonist with more immediate effects - used for infertility






16. MOA of loop diuretics






17. Antidote used for iron salt toxicity






18. Generation of antihistamine that has the most CNS effects






19. Side effect of sotalol






20. SE of niacin






21. Decreases liver triglycerol synthesis






22. Only member of depolarizing neuromuscular blocker - causes fasciculation during induction and muscle pain after use; has short duration of action






23. Antidote used for warfarin toxicity






24. Pyrimidine analog that causes 'Thymine - less death' given with leucovorin rescue






25. DOC for paroxysmal supraventricular tachycardia (PSVT)






26. Antidepressant having stimulant effects similar to SSRI's and can increase blood pressure






27. Drugs of choice for absence seizures






28. Cutaneous flush and be reduced by pretreatment with






29. Alternative anticoagulant used if HIT develops






30. Agent similar to cisplatin - less nephrotoxic - but greater myelosuppression






31. MOA and effect of nitric oxide






32. Maximum response achieveable from a drug






33. Penicillins active against penicillinase secreting bacteria






34. Common SE of spironolactone






35. For rebound HTN from rapid clonidine withdrawal






36. Target plasma concentration times (volume of distribution divided by bioavailability)






37. Cystitis - postoperative bladder spasms - or incontinence






38. Mediator of tissue pain - edema - inactivated by ACE - and may be a contributing factor to the development of angioedema






39. Antidote for tissue plasminogen activator (t - PA) - streptokinase






40. This diuretic decreases aqueous secretion due to lack of HCO3- ion. Causes drowsiness and paresthesias - alkalinization of the urine may precipitate calcium salts - hypokalemia - acidosis






41. Methyldopa is contraindicated in






42. MOA for benzodiazepines






43. Major drug interaction with Quinidine






44. Class III antiarrhythmic that exhibits properties of all 4 classes






45. Neurotoxicity with isoniazid (INH) prevented by






46. Direct vasodilator of arteriolar smooth muscle






47. Similar to clonidine and may cause hypotension






48. Block glycoprotein IIb/IIIa involved in platelet cross - linking






49. Peakless ling acting insulin






50. Endogenous insulin contains







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