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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Main route of metabolism for benzodiazepines






2. Peakless ling acting insulin






3. Class II antiarrhythmics are






4. Short acting Beta 2 agonists that is drug of choice in treatment of acute asthma but not recommended for prophylaxis






5. Common side effect of Rifampin






6. Anti - arrhythmics that decrease mortality






7. Ability to bind reversibly to the same site as the drug and without activating the effector system






8. Antidote to reverse actions of warfarin






9. Benzodiazepines used to promote sleep






10. All opioids except this agent (which has a muscarinic blocking action) cause pupillary constriction






11. Regimen used for breast cancer






12. Agents having active metabolites - long half lives - and a high incidence of adverse effects






13. Reduce transient hyper GI motility






14. SE of CCB






15. Cheap wide spectrum antibiotic DOC for otitis media






16. SE of clonidine






17. Increased risk of developing cataracts






18. MOA of drug or foods (grapefruit juice) that increase statin effect






19. MOA of Bisphosphonates






20. Phenylisopropylamines that are used legitimately and abused for narcolepsy - attention deficit disorder - and weight reduction






21. Nonselective alpha - blocking drug - long acting and irreversible - and used to treat pheochromocytoma. Blocks 5- HT - so occasionaly used for carcinoid tumor. Blocks H1 and used in mastocytosis






22. Four main actions of NSAIDS






23. Thyroxine dose may need to be increased in hypothyroid patient during pregnancy because






24. LA causing methemoglobinemia






25. Sympathetic agent which stimulates heart rate and can dilate vessels in skeletal muscle at low doses






26. MOA of thiazide diuretics






27. Diuretics work in CHF by






28. Incidence of hyoglycemia with metformin






29. NSAID contraindicated in gout






30. Biguanide






31. Opioid used in the management of withdrawal states






32. The most frequent cause of acute deaths in cholinesterase inhibitor toxicity






33. This step of metabolism makes a drug more hydrophilic and hence augments elimination






34. Extrapyramidal dysfunction is more common with these agents - Which block this subtype of dopamine receptor






35. Thrombolytic used for acute MI and ischemic (non hemorrhagic) CVA






36. Clinical uses of these agents include treatment of HTN - angina - arrhythmias - chronic CHF - and selected post MI patients






37. Inhaled anesthetic - less likely to lower blood pressure than other agents - and has the smallest effect on respiration






38. Decreases liver triglycerol synthesis






39. Difference between COX 1 and COX 2






40. First generation sulfonylurea






41. Tolerance is marked and abstinence syndrome occurs






42. Concentration in the plasma times (clearance divided by bioavailability)






43. SE of INH






44. SE of salicylates






45. Anti - seizure drugs used as alternative drugs for mood stabilization






46. Beta 2 agonist toxicity






47. Only direct acting agent that is very lipid soluble and used in glaucoma






48. Interferes with activity of T- lymphocytes






49. These Beta blockers decrease aqueous secretion






50. Anti - malarial drug used in rheumatoid arthritis (RA)