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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Block glycoprotein IIb/IIIa involved in platelet cross - linking






2. ADH agonist used for pituitary diabetes insipidus






3. MOA of Bisphosphonates






4. Scabicide organophosphate






5. Diuretics work in CHF by






6. CCB are DOC for

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7. MOA of thrombolytics






8. Most inhaled anesthetics SE






9. Drugs of choice for status epilepticus






10. Beta blockers work in CHF by






11. These LA's have surface activity






12. Term for a narrow margin of safety






13. Anti - arrhythmic with 15 second duration of action






14. Important in muscle and adipose tissue for glucose transport across muscles and TG storage by lipoprotein lipase activation






15. Long acting sympathomimetic - sometimes used to improve urinary continence in children and elderly with enuresis






16. Antiestrogen drugs used for fertility and breast cancer respectively






17. New class of drugs that works by inhibiting absorption of intestinal cholesterol and can be given concurrently with the Statins






18. Antidote used for anticholinergic poisoning






19. Anti - seizure agent that induces formation of liver drug - metabolism enzymes - is teratogen and can cause craniofacial anomalies and spina bifida






20. Anti - rheumatic agent also used for ulcerative colitis






21. Antidote for methotrexate toxicity






22. Inducers of Cytochrome P450 (CYP450)






23. Thrombolytics are used for






24. Agent used neutropenia especially after chemotherapy






25. HIV med used to reduce transmission during birth






26. Opioids used in anesthesia






27. Inhibitors of catechol - O- methyltransferase (COMT) - used as adjuncts in Parkinson's dx and cause acute hepatic failure (monitor LFT's)






28. Toxicity of organophosphate:






29. Reversal of blockade by neuromuscular blockers






30. Dopamine (DA) agonist (for Parkinson's disease) - used also for hyperprolactinemia






31. Nitrate free intervals are needed due to






32. Major SE of bisphosphonates






33. Longer acting local anesthetics which are less dependent on vasoconstrictors






34. Sedation is a common side effect of these drugs - they lower seizure threshold - uses include BAD - acute panic attacks - phobias - enuresis - and chronic pain and their overdose can be deadly






35. Agents may exacerbate tardive dyskinesias (may be irreversible and there is no treatment)






36. Antiprogestin used as potent antagonist of GC receptor






37. Three C's associated with TCA toxicity






38. These drugs strongly potentiate and prolong effect of neuromuscular blockade (NMB)






39. Treatment of patients with prior episodes of thrombocytopenia after a cycle of cancer chemotherapy






40. Mediator of tissue pain - edema - inactivated by ACE - and may be a contributing factor to the development of angioedema






41. Agent used in drug therapy of Parkinson's instead of Dopamine which has low bioavailability and does not cross the BBB






42. Enhances dopaminergic neurotransmission SE's include CNS excitation - acute toxic psychosis and livedo reticularis






43. Peptide drug used to treat CHF






44. Neurotoxicity with isoniazid (INH) prevented by






45. Alpha - glucosidase inhibitor associated with elevation of LFT's






46. Anti - viral agents associated with Stephen Johnson syndrome






47. Thioamide less likely to cross placenta - inhibits peripheral conversion of T4 to T3 in high doses - and should be used with extreme caution in pregnancy






48. Drug that causes contraction of the uterus






49. Antidote used for opioid toxicity






50. MAOI should not be administered with SSRI's or potent TCA's due to development of this condition