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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
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  • Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Anabolic steroid that has potential for abuse






2. Opioid available trans - dermally






3. SE of these drugs include dependence - withdrawal syndrome - sedation - euphoria - respiratory depression nausea and vomiting - constipation - biliary spasm - increased ureteral and bladder tone - and reduction in uterine tone






4. SE of CCB






5. Sympathetic agent which stimulates heart rate and can dilate vessels in skeletal muscle at low doses






6. Selective Alpha 2 blocker used for impotence (controversial effectiveness)






7. Inhalant anesthetics






8. Vitamin given with calcium to ensure proper absorption






9. Drug ofter used in combination with TNF - alpha inhitors for RA






10. Generation of antihistamine that has the most CNS effects






11. Proteins that prevent action of tumor necrosis factor alpha (TNF- alpha)






12. Methyldopa is contraindicated in






13. Contraindications to use of atropine






14. Nitrate used to prevent further attacks






15. Alpha agonist used to produce mydriasis and reduce conjunctival itching and congestion caused by irritation or allergy - it does not cause cycloplegia






16. Drug used in exoerythrocytic cycle of malaria






17. SE of mirtazapine






18. Cutaneous flush and be reduced by pretreatment with






19. Window between therapeutic effect and toxic effect






20. Treatment of resistant pseudomembranous colitis






21. Antidote for salicylate intoxication






22. GnRH agonist used for infertility or different types of CA depending on pulsatile or steady usage respectively






23. Effective in preventing TIA's






24. Antidepressants with no effect on BP - no sedation






25. Antidote for digoxin toxicity






26. Drug used for N. gonorrhea in females






27. Antidepressant which is inhibitor of CYP450 enzymes and may be associated with hepatic failure






28. Condition will result from in combination of MAOI with tyramine containing foods (ex. wine - cheese - and pickled meats)






29. Anti - androgen used for hirsutism in females






30. CCB contraindicated in CHF






31. DOC for paroxysmal supraventricular tachycardia (PSVT)






32. Agent used in acutely decompensated CHF resembling natriuretic peptide






33. Peptide drug used to treat CHF






34. Beta 2 agonist used to suppress premature labor - but cardiac stimulatory effects may be hazardous to mother and fetus






35. Type of kinetics when a constant percentage of substrate is metabolized per unit time






36. Inhibits conversion of cholesterol to pregnenolone therefore inhibiting corticosteroid synthesis






37. Cholestyramine and colestipol are






38. Overdoses of this agent with powerful vasoconstrictive action may result in fatalities from arrhythmias - seizures - respiratory depression - or severe HTN (MI and stroke)

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39. Weak opioid agonist - poor analgesic - its overdose can cause severe toxicity including respiratory depression - circulatory collapse - pulmonary edema - and seizures






40. Receptors for serotonin (5HT-1) are located






41. Inhaled anesthetics are myocardial depressants






42. Selective alpha agonists that decreases aqueous secretion






43. Most dangerous of the currently popular hallucinogenic drugs - OD leads to nystagmus - marked hypertension - and seizures - presence of both horizontal and vertical nystagmus is pathognomonic






44. Products of Phase II conjugation






45. Drug elimination with a constant amount metabolized regardless of drug concentration






46. SE of nitrates






47. SE of acetaminophen






48. Enhances dopaminergic neurotransmission SE's include CNS excitation - acute toxic psychosis and livedo reticularis






49. The most important sign of withdrawal syndrome






50. Specific pharmacokinetic characteristic of amiodarone







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