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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Inhaled anesthetics metabolized by liver enzymes which has a major role in the toxicity of these agents






2. May protect against doxorubicin toxicity by scavenging free radicals






3. Antidepressant having stimulant effects similar to SSRI's and can increase blood pressure






4. Chelating agent used in acute iron toxicity






5. Anti - arrhythmic with 15 second duration of action






6. TCA used in chronic pain - a hypnotic - and has marked antimuscarinic effects






7. SE of nitrates






8. Used especially in postmenopausal women - dosage should be 1500 mg






9. Metronidazole SE if given with alcohol






10. Class of anti - arrhythmics that has a pro - arrhythmic effect (CAST trial) - therefore are used as last line agents






11. Anticancer drug also used in RA - produces acrolein in urine that leads to hemorrhagic cystitis






12. This beta blocker lacks local anesthetic activity (a property which decreases protective reflexes and increases the risk of corneal ulceration) and used in treating glaucoma






13. For rebound HTN from rapid clonidine withdrawal






14. Major SE of bisphosphonates






15. MOA of corticosteroids






16. Approved for use in severe pulmonary HTN






17. Selectivity of a drug for its receptor






18. Non - depolarizing skeletal muscle antagonist that has short duration






19. Drug causing depletion of substance P (vasodilator)






20. Blows DNA (breaks DNA strands) - limiting SE is pulmonary fibrosis






21. Toxic effect of anticancer drug can be lessened by rescue agents






22. Direct vasodilator of arteriolar smooth muscle






23. Secondary amines that have less sedation and more excitation effect






24. Ultra long acting insulin - has over a day duration of action






25. This produces 'dissociative anesthesia' - is a cardiovascular stimulant which may increases intracranial pressure - and hallucinations occur during recovery






26. 2nd generation antihistamines






27. This beta blocker is the longest acting






28. SE of colchicine






29. MOA of lovastatin (STATIN)






30. DOC to treat chemo - induced nausea and vomiting






31. Agent for pernicious anemia






32. Except for these agents all SSRI have significant inhibition of CytP450 enzymes






33. SE of procainamide






34. DOC for tx of pseudomembranous colitis






35. DOC for Legionnaires' disease






36. Antidote for methotrexate toxicity






37. Agent used for anemias associated with renal failure






38. Common mechanism by which overdose result in death






39. MOA of erythromycin






40. ACE inhibitors are contraindicated in






41. Agents may exacerbate tardive dyskinesias (may be irreversible and there is no treatment)






42. Mineralocorticoids






43. Moderate opioid agonists






44. The fraction of administered dose of a drug that reaches systemic circulation






45. SE of clonidine






46. DOC for CMV retinitis






47. Hormone inhibiting prolactin release






48. Agents used in treatment of carcinoid tumor






49. SE for ticlopidine






50. New class of drugs that works by inhibiting absorption of intestinal cholesterol and can be given concurrently with the Statins