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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. NSAID available orally - IM and ophthalmically






2. Antidote for salicylate intoxication






3. Antidote to reverse actions of warfarin






4. Three C's associated with TCA toxicity






5. Reason benzos are used cautiously in pregnancy






6. Used for Addison's disease - Congenital Adrenal Hyperplasia (CAH) - inflammation - allergies - and asthma (as a local inhalation)






7. Used in pediatrics to maintain patency of ductus arteriosis






8. 1st generation antihistamine that is least sedating






9. Treat manifestations of Parkinson's disease and EPS






10. Anti - arrhythmics that decrease mortality






11. Antiarrhythmic that exhibits Class II and III properties






12. Nonselective alpha - blocking drug - short acting and reversible - used for rebound HTN from rapid clonidine withdrawal - and Raynaud's phenomena






13. Drug used for African sleeping sickness






14. Agents for reduction of postpartum bleeding






15. Increase bone density - also being tested for breast CA prophylaxis






16. Hyperglycemic agent that increases cAMP and results in glycogenolysis - gluconeogenesis - reverses hypoglycemia - also used to reverse severe beta - blocker overdose and smooth muscle relaxation






17. Good hypnotic activity with less CNS SE than most benzodiazepines






18. Dose which is lethal to 50% of the population






19. Agent used for neurological deficits in megaloblastic anemia






20. Prolonged exposure to this inhaled anesthetic may lead to megaloblastic anemia






21. Ergot alkaloid used as an illicit drug






22. CCB are DOC for

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23. Mast cells to reduce release of hisamine and inflammatory mediators






24. SE of niacin






25. Losartan and valsartan block






26. Antidepressant with MOA as alpha 2 antagonist - has effects on both 5- HT and NE - blocks histamine receptors - and is sedating






27. Tubocurarine is the prototype - pancuronium - atracurium - vecuronium are newer short acting agent - produce competitive block at end plate nicotinic receptor - causing flaccid paralysis






28. SE of amrinone






29. Dose may need to be increased during pregnancy or with Ocs due to increased TBG in plasma






30. Bronchodilation in asthma and COPD






31. Clinical response that may fluctuate in tx of Parkinson's dx

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32. Benzodiazepine with useful relaxant effects in skeletal muscle spasticity of central origin






33. ABVD regimen used for HD - but appears less likely to cause sterility and secondary malignancies than MOPP






34. SE of mirtazapine






35. This agent has greater affinity for muscarinic receptors and used for postoperative and neurogenic ileus and urinary retention






36. MOA of corticosteroids






37. Orthostatic hypotension and QT prolongation






38. All antidepressants have roughly the same efficacy in treating depression - agents are chosen based on these criterion






39. These prevent the action of Ach at the skeletal muscle endplate to produce a 'surmountable blockade -' effect is reversed by cholinesterase inhibitors (ex. neostigmine or pyridostigmine)






40. Agent similar to cisplatin - less nephrotoxic - but greater myelosuppression






41. DOC for bipolar affective disorder






42. Diuretic used to antagonize aldosterone receptors






43. Well - tolerated and are first - line antidepressants

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44. Strong opioid agonists






45. Population group especially sensitive to side effects of antidepressants






46. Clinical use for H2 blockers






47. Neurotoxicity with isoniazid (INH) prevented by






48. Antidote for methotrexate toxicity






49. Extrapyramidal dysfunction is more common with these agents - Which block this subtype of dopamine receptor






50. Treatment with cancer chemotherapy at high doses every 3-4 weeks - too toxic to be used continuously