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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Cephalosporins able to cross the BBB






2. Indirect - Acting ACh Agonist - alcohol - short DOA and used in diagnosis of myasthenia gravis






3. Weak opioid agonist - poor analgesic - its overdose can cause severe toxicity including respiratory depression - circulatory collapse - pulmonary edema - and seizures






4. Cutaneous flush and be reduced by pretreatment with






5. SE of HMG COA reductase inhibitors






6. Antidote used for methanol and ethylene glycol






7. Converted to more active form DHT by 5 alpha - reductase






8. SE of mirtazapine






9. Common side effect of Rifampin






10. Antipsychotics that reduce positive symptoms only






11. Examples of alpha - glucosidase inhibitors (AGI)






12. Diuretic used to treat primary aldosteronism






13. Major nutritional side effect of bile acid - binding resins






14. Treatment of withdrawal syndrome involves






15. This agent has greater affinity for muscarinic receptors and used for postoperative and neurogenic ileus and urinary retention






16. SE of salicylates






17. Antivirals associated with neutropenia






18. MOA of loop diuretics






19. MAOI should not be administered with SSRI's or potent TCA's due to development of this condition






20. Rapid acting - crystalline zinc insulin used to reverse acute hyperglycemia






21. Most common SE of fibrates






22. A hormone whose MOA utilizes transmembrane receptors






23. When the rate of drug input equals the rate of drug elimination






24. MOA of class I A (eg. Procainamide) - class IB (eg. Lidocaine) - and class IC (eg. Flecainide) antiarrhythmics






25. Target plasma concentration times (volume of distribution divided by bioavailability)






26. This may antagonize activity of local anesthetics






27. Antiarrhythmic effective in most types of arrhythmia






28. CCB contraindicated in CHF






29. Anti - thyroid drugs






30. 1st generation antihistamine that is highly sedating






31. Cause dizziness - tachycardia - hypotension - and flushing






32. Agent used in acutely decompensated CHF resembling natriuretic peptide






33. Antidote used for iron salt toxicity






34. Reason ergot alkaloids are contraindicated in pregnancy






35. Newer atypical antipsychotics that also improve some of the negative symptoms and help acute agitation






36. Lactam that can be used in PCN allergic patients






37. Short acting Beta 2 agonists that is drug of choice in treatment of acute asthma but not recommended for prophylaxis






38. Used intranasally and decreases bone resorption






39. Reduce transient hyper GI motility






40. Heterocyclic antidepressants least likely to affect sexual performance - used for management of nicotine withdrawal - SE's include dizziness - dry mouth - aggravation of psychosis - and seizures






41. The selective agents loose their selectivity at






42. MOA of repaglinide






43. Anti - viral agents associated with Stephen Johnson syndrome






44. Anti - seizure drugs used also for pain of neuropathic orgin






45. Only phenothiazine not exerting antiemetic effects - can cause visual impairment due to retinal deposits - and high doses have been associated with ventricular arrhythmias






46. These agents are used as antidiarrheal






47. Moderate opioid agonists






48. MOA of class III antiarrhythmics






49. Vitamin given with calcium to ensure proper absorption






50. ABVD regimen used for HD - but appears less likely to cause sterility and secondary malignancies than MOPP