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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Neurotransmitters affected by the action of antidepressants






2. Agent similar to cisplatin - less nephrotoxic - but greater myelosuppression






3. SE of amrinone






4. Increase bone density - also being tested for breast CA prophylaxis






5. Agent effective in physiologic and essential tremor






6. Allopurinol treats chronic gout by decreasing uric acid production by inhibiting






7. Biguanide






8. For rebound HTN from rapid clonidine withdrawal






9. ADH agonist used for pituitary diabetes insipidus






10. Slightly increased risk of breast cancer - endometrial cancer - heart disease (questionable) - has beneficial effects on bone loss






11. Anti - psychotics available in depot preparation






12. SE of hydroxychloroquine






13. Overdoses of this agent with powerful vasoconstrictive action may result in fatalities from arrhythmias - seizures - respiratory depression - or severe HTN (MI and stroke)

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14. Metronidazole SE if given with alcohol






15. NSAID also available as an ophthalmic preparation






16. Products of Phase II conjugation






17. Loops lose and thiazide diuretics retain






18. Tolerance to all effects of opioid agonists can develop except






19. Estrogen mostly used in oral contraceptives (OC)






20. Dose which is lethal to 50% of the population






21. Strength of interaction between drug and its receptor






22. Angiotensin receptor blockers do Not cause






23. Drug used for N. gonorrhea in females






24. Used for Addison's disease - Congenital Adrenal Hyperplasia (CAH) - inflammation - allergies - and asthma (as a local inhalation)






25. Prototype antagonist of H1 and H2 receptors






26. Drug elimination with a constant amount metabolized regardless of drug concentration






27. HIV antiviral class known to have severe drug interactions by causing inhibition of metabolism






28. Chemical antagonists that bind to the inhibitor of ACh Estrace and displace the enzyme (if aging has not occurred)






29. SE of nesiritide






30. SE of CCB






31. Pneumonic for beta receptors






32. Nitrosoureas with high lipophilicity - used for brain tumors






33. DOC for giardia - bacterial vaginosis - pseudomembranous colitis - and trichomonas






34. Agents that block L- type calcium channel






35. Drug used in cancer therapy causes Cushing - like symptoms






36. DOC for influenza A






37. A1a - selective blocker with no effects on HTN used for BPH






38. Additive effects when Sedative - Hypnotics used in combination with these agents






39. Benzodiazepine that has efficacy against absence seizures and in anxiety states - such as agoraphobia






40. Antidote used for organophosphate/anticholinesterase poisoning






41. Shock due to septicemia or myocardial infarction is made worse by






42. Drug used concurrently with toxic anticancer agents to reduce renal precipitation of urates






43. Treatments available for nicotine addiction






44. Available bisphosphonates






45. Antidote used for acetaminophen (APAP) toxicity






46. Methyldopa is contraindicated in






47. Enzyme that metabolizes acetaldehyde to acetate






48. MOA of drug or foods (grapefruit juice) that increase statin effect






49. Barbiturates decrease the effectiveness of many other drugs via this pharmacokinetics property






50. Antidepressant with MOA as alpha 2 antagonist - has effects on both 5- HT and NE - blocks histamine receptors - and is sedating