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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. These beta blockers are less lipid soluble






2. Indirect - Acting ACh Agonist - alcohol - short DOA and used in diagnosis of myasthenia gravis






3. Most common SE of fibrates






4. MOA of both generations






5. Sedative - Hypnotics action






6. Methylxanthine derivative used as a remedy for intermittent claudication






7. Drug used for African sleeping sickness






8. Drug of choice for generalized anxiety disorder - Not effective in acute anxiety






9. Approved for use in severe pulmonary HTN






10. Agents for reduction of postpartum bleeding






11. DOC to treat chemo - induced nausea and vomiting






12. Aminoglycosides used with loop diuretics potentiate adverse effect






13. Weak opioid agonist - poor analgesic - its overdose can cause severe toxicity including respiratory depression - circulatory collapse - pulmonary edema - and seizures






14. Neurotoxicity with isoniazid (INH) prevented by






15. Presynaptic Alpha 2 agonist used in HTN - and acts centrally






16. Anti - psychotics available in depot preparation






17. Anti - viral agents associated with Stephen Johnson syndrome






18. Opioid available trans - dermally






19. Major indication for H1 receptor antagonist






20. Agents acting in the CNS or in the skeletal muscle - used to reduce abnormally elevated tone caused by neurologic or muscle end plate disease






21. Irreversible - nonselective COX inhibitor






22. SSRI with long T1/2 and can be administered once weekly for maintenance - not acute tx






23. Interact with microtubules (but unlike vinca which prevent disassembly of tubules) - it stabilizes tubulin and cells remain frozen in metaphase






24. Plasma concentration of a drug at a given time






25. Side effect of sotalol






26. Tolerance to all effects of opioid agonists can develop except






27. MOA of erythromycin






28. Aspirin is contraindicated in children with viral infection

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29. Cholinomimetics that increase outflow - open trabecular meshwork - and cause ciliary muscle contraction






30. Selectivity of a drug for its receptor






31. H1 antagonist used in motion sickness






32. Common SE of sulfonylureas - repaglinide - and nateglinide






33. DOC for CMV retinitis






34. Diuretic used to treat primary aldosteronism






35. One depolarizing blocker that causes continuous depolarization and results in muscle relaxation and paralysis - causes muscle pain postoperatively and myoglobinuria may occur






36. Some of SSRIs' therapeutic effects beside depression






37. Barbiturates decrease the effectiveness of many other drugs via this pharmacokinetics property






38. Antidote used for benzodiazepine toxicity






39. Extrapyramidal dysfunction is more common with these agents - Which block this subtype of dopamine receptor






40. DMARDs are slow acting drugs for






41. Phenylisopropylamines that are used legitimately and abused for narcolepsy - attention deficit disorder - and weight reduction






42. Selective estrogen receptor modulator (SERM) used for prevention of osteoporosis and prophylaxis in women with risk factors for breast cancer






43. Opioid that can be given PO - by epidural - and IV - which helps to relieve the dyspnea of pulmonary edema






44. Drug that inhibits alcohol dehydrogenase and is used in ethylene glycol exposure






45. Lithium is associated with this congenital defect






46. Interaction with this drug requires dose reduction of 6- MP






47. Anemia caused by trimethoprim






48. Analog of hypoxanthine - needs HGPRTase for activation






49. Anti - androgen used for prostate cancer






50. Pungent inhaled anesthetic which leads to high incidence of coughing and vasospasm