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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. MOA for Valproic acid at high doses






2. Dose which is lethal to 50% of the population






3. Vitamins containing iron should Not be taken simultaneously with levothyroxine because






4. Antiplatelet drug reserved for patients allergic to aspirin






5. Reason ergot alkaloids are contraindicated in pregnancy






6. Sympathetic agent which stimulates heart rate and can dilate vessels in skeletal muscle at low doses






7. SSRI indicated for premenstrual dysphoric disorder






8. Used intravenously for acute arrhythmias during surgery






9. SE of beta blockers






10. Class of antibiotics that have 10% cross sensitivity with penicillins






11. Inhaled anesthetic that may sensitize the myocardium to arrhythmogenic effects of catecholamines and has produced hepatitis






12. Antidote used for iron salt toxicity






13. Condition will result from in combination of MAOI with tyramine containing foods (ex. wine - cheese - and pickled meats)






14. Term for a high margin of safety






15. MOA of class IV antiarrhythmics






16. These LA's have surface activity






17. COX 2 inhibitors should be used cautiously in pts with






18. Agent that is the antidote for methanol overdose






19. Alpha - glucosidase inhibitor associated with elevation of LFT's






20. NSAID used in gout






21. Peakless ling acting insulin






22. MOA of class I A (eg. Procainamide) - class IB (eg. Lidocaine) - and class IC (eg. Flecainide) antiarrhythmics






23. SE for ganciclovir






24. Osmotic diuretic used to treat increased intracranial pressure






25. MOA of Leflunomide (newer agent)






26. Drugs of choice for absence seizures






27. Selective Alpha 2 blocker used for impotence (controversial effectiveness)






28. Regimen used for breast cancer






29. Agent having no effect on D2 receptors - blocks D4 - reserved for resistant schizophrenia - and can cause fatal agranulocytosis






30. Anticancer drug also used in RA - produces acrolein in urine that leads to hemorrhagic cystitis






31. Vitamin given with calcium to ensure proper absorption






32. Epinephrine is often mixed with a local anesthetic to






33. Anti - microbials that cause hemolysis in G6PD- deficient patients






34. DOC for RSV






35. Agent with long duration of action and is most likely to cause histamine release






36. SE seen only in men with administration of ketoconazole






37. HIV antiviral class known to have severe drug interactions by causing inhibition of metabolism






38. Type of kinetics when a constant percentage of substrate is metabolized per unit time






39. Reason fluoroquinolones are contraindicated in children and pregnancy






40. Occurs when sedative hypnotics are used chronically or at high doses






41. ABVD regimen used for HD - but appears less likely to cause sterility and secondary malignancies than MOPP






42. Except for these agents all SSRI have significant inhibition of CytP450 enzymes






43. Longer acting benzodiazepines used in the management of withdrawal states of alcohol and other drugs






44. NSAID that is used for acute condition - such as pre - op anesthesia and has limited duration (<5 days) of use due to nephrotoxicity






45. MOA of both generations






46. Maximum response achieveable from a drug






47. Phenylisopropylamines that are used legitimately and abused for narcolepsy - attention deficit disorder - and weight reduction






48. SE of lithium






49. Period of time of therapy after which GC therapy will need to be tapered






50. What do delta cells in the pancreas produce?