Test your basic knowledge |

USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Partial opioid agonist - considered a strong analgesic - has a long duration of action and is resistant to naloxone reversal






2. Pyrimidine analog that causes 'Thymine - less death' given with leucovorin rescue






3. Agent that inhibits hepatic metabolism - is hepatotoxic and teratogen that can cause neural tube defects and gastrointestinal distress






4. DOC for bipolar affective disorder






5. Long acting sympathomimetic - sometimes used to improve urinary continence in children and elderly with enuresis






6. Class of drugs that reversibly inhibit COX






7. Analog of hypoxanthine - needs HGPRTase for activation






8. Antidote for beta - blockers and hypoglycemia






9. This is combined with L- dopa - inhibits DOPA decarboxylase (active only peripherally) which allows lower effective doses of L- dopa and allows for fewer SE's (GI distress - postural hypotension - and dyskinesias)






10. This route is associated with rapid tolerance and psychologic dependence






11. Anti - biotic frequently used for chronic UTI prophylaxis






12. Used for SIADH






13. Antidepressant with MOA as alpha 2 antagonist - has effects on both 5- HT and NE - blocks histamine receptors - and is sedating






14. The most important sign of withdrawal syndrome






15. Losartan and valsartan block






16. SE for Felbamate






17. Where are beta cells found in the pancreas?






18. Combined alpha and beta blocking agents that may have application in treatment of CHF






19. Anti - arrhythmic with 15 second duration of action






20. Lactam that can be used in PCN allergic patients






21. SE of spironolactone






22. CCB contraindicated in CHF






23. MOA of class III antiarrhythmics






24. These drugs strongly potentiate and prolong effect of neuromuscular blockade (NMB)






25. Neurotoxicity with isoniazid (INH) prevented by






26. Anti - seizure agent that exhibits non - linear metabolism - highly protein bound - causes fetal hydantoin syndrome - and stimulates hepatic metabolism






27. Median effective dose required for an effect in 50% of the population






28. This beta blocker is highly lipid soluble and may account for side effects such as nightmares






29. Time it takes for amount of drug to fall to half of its value; this is a constant in first order kinetics (majority of drugs)






30. Proteins that prevent action of tumor necrosis factor alpha (TNF- alpha)






31. Anti - psychotics available in depot preparation






32. Amount of drug necessary to elicit a biologic effect; refers to the drug's strength






33. Some of SSRIs' therapeutic effects beside depression






34. Drug that inhibits alcohol dehydrogenase and is used in ethylene glycol exposure






35. Common SE of tamoxifen and raloxifene






36. Penicillins active against penicillinase secreting bacteria






37. Type of resistance found with vancomycin






38. Antivirals that are teratogens






39. Antipsychotics that reduce positive symptoms only






40. Antidepressant which is inhibitor of CYP450 enzymes and may be associated with hepatic failure






41. Nonselective alpha - blocking drug - long acting and irreversible - and used to treat pheochromocytoma. Blocks 5- HT - so occasionaly used for carcinoid tumor. Blocks H1 and used in mastocytosis






42. Bleomycin+vinblastine+etoposide+cisplatin produce almost a 100% response when all agents are used for this neoplasm






43. Agent used to treat MI and to reduce incidence of subsequent MI






44. Monitoring parameter to obtain before initiation of STATINS

Warning: Invalid argument supplied for foreach() in /var/www/html/basicversity.com/show_quiz.php on line 183


45. Oral antibiotic of choice for moderate inflammatory acne






46. SE of hydralazine






47. These agents are congeners of Amphetamine

Warning: Invalid argument supplied for foreach() in /var/www/html/basicversity.com/show_quiz.php on line 183


48. Period of time of therapy after which GC therapy will need to be tapered






49. Metronidazole SE if given with alcohol






50. Chelating agent used in acute iron toxicity