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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Inhaled anesthetics metabolized by liver enzymes which has a major role in the toxicity of these agents






2. Drug causing depletion of substance P (vasodilator)






3. Opioid antagonist that is given orally in alcohol dependency programs






4. Losartan and valsartan block






5. Limiting adverse effect of ganglion blockade that patients usually are unable to tolerate






6. Antidepressant with MOA as alpha 2 antagonist - has effects on both 5- HT and NE - blocks histamine receptors - and is sedating






7. Regimen used for breast cancer






8. Epinephrine is often mixed with a local anesthetic to






9. Antipsychotic having the strongest autonomic effects






10. These agents are used as antidiarrheal






11. Agent for pernicious anemia






12. Vascular effects of metformin






13. Orthostatic hypotension and QT prolongation






14. MOA of class III antiarrhythmics






15. Constant low dose of estrogen and increasing dose of progestin for 21 days (last 5 days are sugar pills or iron prep)






16. Period of time of therapy after which GC therapy will need to be tapered






17. Beta 2 agonist used to suppress premature labor - but cardiac stimulatory effects may be hazardous to mother and fetus






18. SE of loop (furosemide) diuretics






19. Long acting sympathomimetic - sometimes used to improve urinary continence in children and elderly with enuresis






20. Inhibit angiotensin - converting enzyme (ACE)






21. Agent used in CHF that is a selective alpha and nonselective beta blocker






22. Block glycoprotein IIb/IIIa involved in platelet cross - linking






23. Example of three antidepressants that are indicated for obsessive compulsive disorder






24. Fibrates (gemfibrozil) increase activity of






25. This is combined with L- dopa - inhibits DOPA decarboxylase (active only peripherally) which allows lower effective doses of L- dopa and allows for fewer SE's (GI distress - postural hypotension - and dyskinesias)






26. ADH agonist used for pituitary diabetes insipidus






27. Most common side effect of 1st generation antihistamines






28. Drug used in exoerythrocytic cycle of malaria






29. Chemical antagonists that bind to the inhibitor of ACh Estrace and displace the enzyme (if aging has not occurred)






30. Aminoglycoside that is least ototoxic






31. Agent used in acutely decompensated CHF resembling natriuretic peptide






32. Antipsychotic having the weakest autonomic effects






33. SE for Lamotrigine






34. Class of anti - arrhythmics that has a pro - arrhythmic effect (CAST trial) - therefore are used as last line agents






35. Topical DOC in impetigo






36. MOA of tetracycline






37. Prostaglandin used in the treatment of impotence






38. Anti - seizure drugs used also for Trigeminal neuralgia






39. Antidote used for beta agonist toxicity (eg. Metaproterenol)






40. Angiotensin receptor blockers do Not cause






41. Thrombolytics are used for






42. Drug used in ergot alkaloids overdose - ischemia and gangrene






43. Antidote used for lead poisoning






44. Benzodiazepine that has efficacy against absence seizures and in anxiety states - such as agoraphobia






45. TCA used in obsessive compulsive disorder (OCD) - most significant of TCA's for risk of seizure - weight gain - and neuropsychiatric signs and symptoms






46. Oral antibiotic of choice for moderate inflammatory acne






47. Agent that inhibits hepatic metabolism - is hepatotoxic and teratogen that can cause neural tube defects and gastrointestinal distress






48. Skeletal muscle agent that undergoes Hofmann elimination (breaks down spontaneously)






49. Antidote to reverse actions of heparin






50. Used for SIADH