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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Drug used in exoerythrocytic cycle of malaria






2. SE of spironolactone






3. Mineralocorticoids






4. Atypical antipsychotic causing high prolactin levels






5. Rapid acting insulins that do not self - aggregate






6. This is the drug of choice for anaphylactic shock






7. Toxicity of anticholinergics






8. The ratio of the rate of elimination of a drug to its plasma concentration






9. Antidote for hyperkalemia






10. Inhibit synaptic activity of primary afferents and spinal cord pain transmission neurons






11. Agent that inhibits hepatic metabolism - is hepatotoxic and teratogen that can cause neural tube defects and gastrointestinal distress






12. Chemical antagonists that bind to the inhibitor of ACh Estrace and displace the enzyme (if aging has not occurred)






13. Lethal arrhythmias resulting from concurrent therapy with azole fungals (metabolized by CYP 3A4) and these antihistamines which inhibit the 3A4 iso - enzyme.






14. Class III antiarrhythmic that exhibits properties of all 4 classes






15. Mast cells to reduce release of hisamine and inflammatory mediators






16. Benzodiazepine used for anxiety






17. Commonly abused LA which has cardiovascular toxicity including severe hypertension with cerebral hemorrhage - cardiac arrhythmias - and myocardial infarction






18. SE of OCs






19. Nonselective alpha - blocking drug - short acting and reversible - used for rebound HTN from rapid clonidine withdrawal - and Raynaud's phenomena






20. DOC for herpes and its MOA






21. Benzodiazepines used to promote sleep






22. Limiting adverse effect of ganglion blockade that patients usually are unable to tolerate






23. Generation of antihistamine that has the most CNS effects






24. Very rapid acting insulin - having fastest onset and shortest duration of action






25. Non - benzodiazepine used as an anxiolytic






26. Major SE of zileuton






27. Agent which stimulates cardiac contractile force more than rate with little effect on total peripheral resistance






28. Long acting glucocorticoids






29. Non ergot agents used as first - line therapy in the initial management of Parkinson's






30. Relates the amount of drug in the body to the plasma concentration






31. Inhibitor of leukotrienes (LTD4) receptors and used in asthma






32. What do delta cells in the pancreas produce?






33. Orthostatic hypotension and QT prolongation






34. Analog of hypoxanthine - needs HGPRTase for activation






35. Common mechanism by which overdose result in death






36. Common toxicities of cisplatin






37. CCB contraindicated in CHF






38. Nitrate used for acute anginal attacks






39. Nitrosoureas with high lipophilicity - used for brain tumors






40. Skeletal muscle agent that can block muscarinic receptors






41. Anti - estrogen used for estrogen receptor + breast cancer






42. Anti - seizure drugs used also for pain of neuropathic orgin






43. Initial DMARD of choice for patients with RA






44. What do beta cells in the pancreas produce?






45. This is combined with L- dopa - inhibits DOPA decarboxylase (active only peripherally) which allows lower effective doses of L- dopa and allows for fewer SE's (GI distress - postural hypotension - and dyskinesias)






46. SE of colchicine






47. Agents used in treatment of carcinoid tumor






48. Somatotropin (GH) analog used in GH deficiency (dwarfism)






49. Toxicity of amphotericin






50. Constant proportion of cell population killed rather than a constant number