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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Activation of these receptors open K+ ion channels to cause membrane hyperpolarization






2. Ability to bind reversibly to the same site as the drug and without activating the effector system






3. MOA of AGI's






4. SE of hydroxychloroquine






5. Drug notorious for causing pseudomembranous colitis






6. Anti - estrogen used for estrogen receptor + breast cancer






7. Anti - seizure drugs used also for bipolar affective disorder (BAD)






8. Antidote used for carbon monoxide poisoning






9. SSRI less likely to cause a withdrawal syndrome






10. Chemical antagonists that bind to the inhibitor of ACh Estrace and displace the enzyme (if aging has not occurred)






11. Antipsychotics that reduce positive symptoms only






12. Interaction with this drug requires dose reduction of 6- MP






13. Benzodiazepines used to promote sleep






14. Beta 1 agonists used in acute CHF






15. Block glycoprotein IIb/IIIa involved in platelet cross - linking






16. Four main actions of NSAIDS






17. Antidote used for opioid toxicity






18. Antiprogestin used as potent antagonist of GC receptor






19. Drug of choice for generalized anxiety disorder - Not effective in acute anxiety






20. MOA of local anesthetics (LA's)






21. PCN active against pseudomonas






22. Selective Alpha -1A blocker - used for BPH - but with little effect on HTN






23. Beta 2 agonist used to suppress premature labor - but cardiac stimulatory effects may be hazardous to mother and fetus






24. Only direct acting agent that is very lipid soluble and used in glaucoma






25. This agent regenerates active cholinesterase and is a chemical antagonist used to treat organophosphate exposure






26. SE of amrinone






27. Cholinomimetics that increase outflow - open trabecular meshwork - and cause ciliary muscle contraction






28. Monitoring parameter to obtain before initiation of STATINS

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29. MOA of thiazide diuretics






30. Decreases liver triglycerol synthesis






31. Anticoagulant of choice in pregnancy






32. Reason fluoroquinolones are contraindicated in children and pregnancy






33. GABA agonist in the spinal cord






34. Anti - arrhythmics that decrease mortality






35. NSAID that is used for acute condition - such as pre - op anesthesia and has limited duration (<5 days) of use due to nephrotoxicity






36. GHRH analog used as diagnostic agent






37. Aspirin is contraindicated in children with viral infection

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38. Alternative anticoagulant used if HIT develops






39. Class of drugs that may cause cross - sensitivity with thiazide diuretics






40. IV Drug used Hypertensive Crisis






41. MOA of quinolones






42. Irreversible - nonselective COX inhibitor






43. Thrombolytic that can cause allergic reaction






44. Vascular effects of metformin






45. MOA of Leflunomide (newer agent)






46. Antidote for methotrexate toxicity






47. Fibrates (gemfibrozil) increase activity of






48. Aspirin reduces mortality in unstable angina by






49. Agent used to treat chronic gout by increasing uric acid secretion and excretion






50. THC is active ingredient - SE's include impairment of judgment - and reflexes - decreases in blood pressure and psychomotor performance occur