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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Extrapyramidal dysfunction is more common with these agents - Which block this subtype of dopamine receptor






2. Most common side effect of 1st generation antihistamines






3. Sedation is a common side effect of these drugs - they lower seizure threshold - uses include BAD - acute panic attacks - phobias - enuresis - and chronic pain and their overdose can be deadly






4. 1st generation antihistamine that is highly sedating






5. Penicillins active against penicillinase secreting bacteria






6. Withdrawal from this drug causes lethargy - irritability - and headache






7. Atropine fever is the most dangerous effect and can be lethal in this population group






8. Inhaled anesthetic - less likely to lower blood pressure than other agents - and has the smallest effect on respiration






9. SE of phenytoin






10. Diuretic used to treat primary aldosteronism






11. Drugs of choice for generalized tonic - clonic and partial seizures






12. SSRI less likely to cause a withdrawal syndrome






13. MOA for benzodiazepines and barbiturates






14. Site of action of loop diuretics






15. SE of these drugs include dependence - withdrawal syndrome - sedation - euphoria - respiratory depression nausea and vomiting - constipation - biliary spasm - increased ureteral and bladder tone - and reduction in uterine tone






16. SE of loop (furosemide) diuretics






17. THC is active ingredient - SE's include impairment of judgment - and reflexes - decreases in blood pressure and psychomotor performance occur






18. Newer alpha 2 agonist (apraclonidine and brimonidine) treat glaucoma by acting to






19. Regimen used for breast cancer






20. Additive effects when Sedative - Hypnotics used in combination with these agents






21. H2 blocker that causes the most interactions with other drugs






22. Antidote used for iron salt toxicity






23. DOC for management of acute ventricular arrhythmias






24. Antidepressant also used for sleep that causes priapism






25. 1st generation antihistamine that is least sedating






26. Thioamide less likely to cross placenta - inhibits peripheral conversion of T4 to T3 in high doses - and should be used with extreme caution in pregnancy






27. B- blockers that are more cardioselective






28. Prolonged exposure to this inhaled anesthetic may lead to megaloblastic anemia






29. Anti - Parkinson's drug which increases intraocular pressure and is contraindicated in closed angle glaucoma






30. These agents are used as antidiarrheal






31. Used for prevention of postmenopausal osteoporosis in women






32. Cause dizziness - tachycardia - hypotension - and flushing






33. Slightly increased risk of breast cancer - endometrial cancer - heart disease (questionable) - has beneficial effects on bone loss






34. Used for Cushing's syndrome (increased corticosteroid)






35. Antiprogestin used as potent antagonist of GC receptor






36. Drugs of choice for absence seizures






37. Aminoglycosides used with loop diuretics potentiate adverse effect






38. Selective Alpha -1A blocker - used for BPH - but with little effect on HTN






39. These Beta blockers decrease aqueous secretion






40. Diuretics work in CHF by






41. Antipsychotic used in the treatment of psychiatric symptoms in patients with dementia






42. All opioids except this agent (which has a muscarinic blocking action) cause pupillary constriction






43. Use of this opioid with MAOI can lead to hyperpyrexic coma - and with SSRI's can lead to serotonin syndrome






44. Thiazolidinediones






45. Major effect of benzodiazepines on sleep at high doses






46. Facilitates GABA presynaptic inhibition






47. Agents having higher sedation and antimuscarinic effects than other TCA's






48. Vitamin K dependent anticoagulant






49. Anti - androgen used for prostate cancer






50. Neurotoxicity with isoniazid (INH) prevented by