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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Shock due to septicemia or myocardial infarction is made worse by






2. Drug used for MRSA






3. This agent regenerates active cholinesterase and is a chemical antagonist used to treat organophosphate exposure






4. Fluoride released by metabolism of this inhaled anesthetic may cause renal insufficiency






5. Agents acting in the CNS or in the skeletal muscle - used to reduce abnormally elevated tone caused by neurologic or muscle end plate disease






6. Leads to respiratory depression progressing to coma and death






7. Drug used in exoerythrocytic cycle of malaria






8. Produces both rapid anesthesia and recovery - has antiemetic activity and commonly used for outpatient surgery - may cause marked hypotension






9. Ability of a drug to produce 100% of the maximum response regardless of the potency






10. Antiestrogen drugs used for fertility and breast cancer respectively






11. Drugs of choice for generalized tonic - clonic and partial seizures






12. Ability to produce less than 100% of the response






13. Anti - seizure drugs used as alternative drugs for mood stabilization






14. SE of Thiazolindinediones






15. MOA of colchicine (used in acute gout)






16. Non - selective Alpha1blockers use to treat pheochromocytoma






17. These beta blockers are less lipid soluble






18. Direct vasodilator of arteriolar smooth muscle






19. Meningitis prophylaxis in exposed patients






20. Thrombolytic that can cause allergic reaction






21. Additive effects when Sedative - Hypnotics used in combination with these agents






22. Antidote for acetaminophen toxicity






23. These drugs strongly potentiate and prolong effect of neuromuscular blockade (NMB)






24. Aspirin reduces mortality in unstable angina by






25. All antidepressants have roughly the same efficacy in treating depression - agents are chosen based on these criterion






26. Causes acne - premature closure of epiphyses - masculinization in females - hepatic dysfunction - MI - and increases in libido and aggression






27. Agent that is a partial agonist for the 5- HT1A receptor






28. Class of drugs that may cause cross - sensitivity with thiazide diuretics






29. Antidote used for heparin overdose






30. Tubocurarine is the prototype - pancuronium - atracurium - vecuronium are newer short acting agent - produce competitive block at end plate nicotinic receptor - causing flaccid paralysis






31. MOA for benzodiazepines






32. Major SE of zileuton






33. SE of mirtazapine






34. SE of OCs






35. Ability to bind reversibly to the same site as the drug and without activating the effector system






36. TCA with greatest sedation of this group - and marked antimuscarinic effects - used for sleep






37. Very rapid acting insulin - having fastest onset and shortest duration of action






38. Converted to more active form DHT by 5 alpha - reductase






39. Relates the amount of drug in the body to the plasma concentration






40. SE of demeclocycline






41. Ultra long acting insulin - has over a day duration of action






42. Benzodiazepines used to promote sleep






43. COX 2 inhibitors should be used cautiously in pts with






44. Antidote for arsenic - mercury - lead - and gold poisoning






45. SE of imipenem






46. Antidepressant which is inhibitor of CYP450 enzymes and may be associated with hepatic failure






47. Life threatening cardiac event that prolong QT leads to






48. SE of hydralazine






49. Alpha - glucosidase inhibitor associated with elevation of LFT's






50. Inhalant anesthetics







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