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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
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  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Causes acne - premature closure of epiphyses - masculinization in females - hepatic dysfunction - MI - and increases in libido and aggression






2. Biguanide






3. Anticoagulant of choice in pregnancy






4. Names of three bisphosphonates available IV






5. Newer atypical antipsychotics that also improve some of the negative symptoms and help acute agitation






6. Example of three antidepressants that are indicated for obsessive compulsive disorder






7. SE of amrinone






8. Leads to respiratory depression progressing to coma and death






9. Anti - seizure medication also used in the prevention of migraines






10. Can be effective for short term therapy of thyroid storm - but after several weeks of therapy causes an exacerbation of hyperthyroidism






11. Strong opioid agonists






12. Exogenous insulin contains






13. Drugs of choice for status epilepticus






14. Agent used to treat MI and to reduce incidence of subsequent MI






15. Anti - malarial drug used in rheumatoid arthritis (RA)






16. Different steps of Phase I






17. Antivirals associated with neutropenia






18. Antidote for beta - blockers and hypoglycemia






19. This is the drug of choice for anaphylactic shock






20. NSAID that is used for acute condition - such as pre - op anesthesia and has limited duration (<5 days) of use due to nephrotoxicity






21. Common toxicities of cisplatin






22. Radio contrast media that inhibits the conversion of T4 to T3






23. Sympathetic agent which stimulates heart rate and can dilate vessels in skeletal muscle at low doses






24. Slightly increased risk of breast cancer - endometrial cancer - heart disease (questionable) - has beneficial effects on bone loss






25. Drug causing depletion of substance P (vasodilator)






26. MOA for benzodiazepines and barbiturates






27. Antidepressant having stimulant effects similar to SSRI's and can increase blood pressure






28. Antidepressants with no effect on BP - no sedation






29. Agents used in Huntington's Disease






30. Thrombolytic that can cause allergic reaction






31. These agents are used as antidiarrheal






32. Class of drugs that reversibly inhibit COX






33. Inhaled anesthetic with a low blood/gas partition coefficient






34. Sulfonylurea Not recommended for elderly because of very long half life






35. Long acting sympathomimetic - sometimes used to improve urinary continence in children and elderly with enuresis






36. Inhibit synaptic activity of primary afferents and spinal cord pain transmission neurons






37. Bronchodilation in asthma and COPD






38. Readily detected markers that may assist in diagnosis of the cause of a drug overdose include






39. Antidote used for organophosphate/anticholinesterase poisoning






40. Muscarinic antagonist used in asthma






41. Benzodiazepine that undergo extrahepatic conjugation (which are useful in older or hepatically impaired)






42. Pneumonic for 3 zones of adrenal cortex






43. This produces 'dissociative anesthesia' - is a cardiovascular stimulant which may increases intracranial pressure - and hallucinations occur during recovery






44. Drugs used in the management of angina






45. Presynaptic Alpha 2 agonist used in HTN - and acts centrally






46. MOA of class III antiarrhythmics






47. Prostaglandin used in the treatment of impotence






48. Alpha 1 agonist toxicity






49. SE for ticlopidine






50. Newer estrogen receptor antagonist used in advanced breast cancer






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