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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Agent used to treat MI and to reduce incidence of subsequent MI






2. SSRI less likely to cause a withdrawal syndrome






3. The fraction of administered dose of a drug that reaches systemic circulation






4. Adenosine's MOA






5. Indirect - Acting ACh Agonist - alcohol - short DOA and used in diagnosis of myasthenia gravis






6. Treatment with cancer chemotherapy at high doses every 3-4 weeks - too toxic to be used continuously






7. SE of alpha blockers






8. MOA of class III antiarrhythmics






9. Usual time needed for full effect of antidepressant therapy






10. Rapid acting insulins that do not self - aggregate






11. Agents acting in the CNS or in the skeletal muscle - used to reduce abnormally elevated tone caused by neurologic or muscle end plate disease






12. Site of action of thiazide diuretics






13. Drug is used with testosterone for male fertility






14. Newer alpha 2 agonist (apraclonidine and brimonidine) treat glaucoma by acting to






15. Ultra long acting insulin - has over a day duration of action






16. Newer atypical antipsychotic used for bipolar disorder - known to cause weight gain - and adversely affect diabetes






17. Agents for reduction of postpartum bleeding






18. MOA of Cardiac glycosides (eg. digoxin)






19. Peptide drug used to treat CHF






20. Drug that selectively inhibits COX 2






21. MOA of general anesthetics






22. Activation of these receptors open K+ ion channels to cause membrane hyperpolarization






23. Most inhaled anesthetics SE






24. Except for these agents all SSRI have significant inhibition of CytP450 enzymes






25. Ability to bind reversibly to the same site as the drug and without activating the effector system






26. Cholinomimetics that increase outflow - open trabecular meshwork - and cause ciliary muscle contraction






27. Toxicities include nephrotoxicity and ototoxicity - leading to a severe interaction with aminoglycosides






28. Used intranasally and decreases bone resorption






29. The most important sign of withdrawal syndrome






30. Used intravenously for acute arrhythmias during surgery






31. Agents used in Huntington's Disease






32. TCA with greatest sedation of this group - and marked antimuscarinic effects - used for sleep






33. Antidepressant inhibiting norepinephrine - serotonin - and dopamine reuptake






34. Neurotoxicity with isoniazid (INH) prevented by






35. SE of ACE inhibitors






36. Nitrate used to prevent further attacks






37. Interferes with activity of T- lymphocytes






38. The elimination of drug that occurs before it reaches the systemic circulation






39. Antidote used in poisonings: copper (Wilson's disease) - lead - mercury - and arsenic






40. Angiotensin receptor blockers do Not cause






41. Window between therapeutic effect and toxic effect






42. Diuretic used to antagonize aldosterone receptors






43. CCB with predominate effect on arteriole dilation






44. Patients being treated with lithium - who are dehydrated - or taking diuretics concurrently - could develop






45. Only member of depolarizing neuromuscular blocker - causes fasciculation during induction and muscle pain after use; has short duration of action






46. Agent having no effect on D2 receptors - blocks D4 - reserved for resistant schizophrenia - and can cause fatal agranulocytosis






47. These agents increase cardiac output and may be beneficial in treatment of acute heart failure and some types of shock






48. Drug increases the renal clearance hence decreases levels of lithium






49. Cutaneous flush and be reduced by pretreatment with






50. Anti - psychotic not shown to cause tardive dyskinesia