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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Nitrosoureas with high lipophilicity - used for brain tumors






2. MOA of nystatin






3. Reason ergot alkaloids are contraindicated in pregnancy






4. MOA for Ethosuximide






5. Diuretic used for mountain sickness and glaucoma






6. SE of nitrates






7. Treatment of resistant pseudomembranous colitis






8. Cardioselective Beta 1- blockers






9. SE of beta blockers






10. Toxicity of these agents include bradycardia - AV blockade - exacerbation of acute CHF; signs of hypoglycemia may be masked (tachycardia - tremor - and anxiety)






11. Beta 2 agonist toxicity






12. ADH agonist used for pituitary diabetes insipidus






13. SE of thiazide (HCTZ) diuretics






14. Agent more frequently associated with extrapyramidal side effects that can be treated with benzodiazepine - diphenhydramine or muscarinic blocker






15. Methylxanthine derivative used as a remedy for intermittent claudication






16. MOA of aspirin






17. NSAID also available as an ophthalmic preparation






18. Antidote used for organophosphate/anticholinesterase poisoning






19. Term for a narrow margin of safety






20. Important in synthesis of glucose to glycogen in the liver






21. This beta blocker is the longest acting






22. Other side effects of Quinidine






23. This may antagonize activity of local anesthetics






24. SE of loop (furosemide) diuretics






25. Facilitates GABA presynaptic inhibition






26. Enzyme that metabolizes acetaldehyde to acetate






27. Vascular effects of metformin






28. Most dangerous of the currently popular hallucinogenic drugs - OD leads to nystagmus - marked hypertension - and seizures - presence of both horizontal and vertical nystagmus is pathognomonic






29. Angiotensin receptor blockers do Not cause






30. Agents used in Huntington's Disease






31. Life threatening cardiac event that prolong QT leads to






32. CCB are DOC for

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33. Usual time needed for full effect of antidepressant therapy






34. Long acting insulin






35. Treatment of myasthenia gravis






36. DOC for RSV






37. Concentration in the plasma times (clearance divided by bioavailability)






38. Indirect - Acting ACh Agonist - alcohol - short DOA and used in diagnosis of myasthenia gravis






39. Anti - androgen used for hirsutism in females






40. Drug is used with testosterone for male fertility






41. Additive effects when Sedative - Hypnotics used in combination with these agents






42. Constant low dose of estrogen and increasing dose of progestin for 21 days (last 5 days are sugar pills or iron prep)






43. Neurotoxicity with isoniazid (INH) prevented by






44. Selective Alpha 1 blocker used for hypertension - BPH - may cause first dose orthostatic hypotension






45. TCA used in chronic pain - enuresis - and ADD






46. W/D from this drug causes anxiety and mental discomfort






47. The most toxic organophosphate






48. Antidepressant inhibiting norepinephrine - serotonin - and dopamine reuptake






49. SE of hydralazine






50. Converts asparagine to aspartate and ammonia - denies cancer cells of essential AA (asparagine)