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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Most important potential SE of metformin






2. Most frequent route of metabolism






3. These agents decrease blood flow or increase blood pressure - are local decongestants - and used in therapy of spinal shock (temporary maintenance of blood pressure which may help maintain perfusion






4. Anti - seizure agent that induces formation of liver drug - metabolism enzymes - is teratogen and can cause craniofacial anomalies and spina bifida






5. This is the drug of choice for anaphylactic shock






6. Alpha agonist used to produce mydriasis and reduce conjunctival itching and congestion caused by irritation or allergy - it does not cause cycloplegia






7. Methylxanthine derivative used as a remedy for intermittent claudication






8. GABA agonist in the spinal cord






9. Rapid acting insulins that do not self - aggregate






10. Common SE of spironolactone






11. Peakless ling acting insulin






12. Toxicity of organophosphate:






13. DOC for bipolar affective disorder






14. Alpha 1 agonist toxicity






15. Antidote for salicylate intoxication






16. Antidote for thrombolytics






17. Class III antiarrhythmic that exhibits properties of all 4 classes






18. DOC for paroxysmal supraventricular tachycardia; has high efficacy and short duration of action






19. Aminoglycosides used with loop diuretics potentiate adverse effect






20. 5HT-3 antagonist that has been associated with QRS and QTc prolongation and should not be used in patients with heart disease






21. Prostaglandins that cause abortions






22. Regimen used for non - Hodgkin's lymphoma






23. Vitamins containing iron should Not be taken simultaneously with levothyroxine because






24. SE of imipenem






25. 5HT-3 antagonist used in chemotherapeutic induced emesis






26. MOA of drug or foods (grapefruit juice) that increase statin effect






27. TCA used in chronic pain - enuresis - and ADD






28. MOA of sulfonamides






29. Term for a high margin of safety






30. Toxicities include nephrotoxicity and ototoxicity - leading to a severe interaction with aminoglycosides






31. DOC to treat chemo - induced nausea and vomiting






32. Penicillins active against penicillinase secreting bacteria






33. Direct vasodilator of arteriolar smooth muscle






34. Lacrimation - rhinorrhea - yawning - sweating - weakness - gooseflesh - nausea - and vomiting - tremor - muscle jerks - and hyperpnea are signs of this syndrome






35. GHRH analog used as diagnostic agent






36. Somatotropin (GH) analog used in GH deficiency (dwarfism)






37. Combined alpha and beta blocking agents that may have application in treatment of CHF






38. Agent that is a partial agonist for the 5- HT1A receptor






39. Three C's associated with TCA toxicity






40. Atypical antipsychotic causing high prolactin levels






41. MOA of loop diuretics






42. Agent with long duration of action and is most likely to cause histamine release






43. Non ergot agents used as first - line therapy in the initial management of Parkinson's






44. SE of lithium






45. All opioids except this agent (which has a muscarinic blocking action) cause pupillary constriction






46. Class of anti - arrhythmics that has a pro - arrhythmic effect (CAST trial) - therefore are used as last line agents






47. Agent used to treat MI and to reduce incidence of subsequent MI






48. Drugs of choice for absence seizures






49. Antidote for arsenic - mercury - lead - and gold poisoning






50. MAOI should not be administered with SSRI's or potent TCA's due to development of this condition