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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Approved for use in severe pulmonary HTN






2. Converts asparagine to aspartate and ammonia - denies cancer cells of essential AA (asparagine)






3. Digoxin toxicity can be precipitated by






4. Prolonged exposure to this inhaled anesthetic may lead to megaloblastic anemia






5. Similar to clonidine and may cause hypotension






6. The selective agents loose their selectivity at






7. Agent to treat hypochromic microcytic anemias






8. Hormone inhibiting prolactin release






9. Increase bone density - also being tested for breast CA prophylaxis






10. Nitrate free intervals are needed due to






11. Longer acting benzodiazepines used in the management of withdrawal states of alcohol and other drugs






12. Agent used in CHF that is a selective alpha and nonselective beta blocker






13. Agent used in drug therapy of Parkinson's instead of Dopamine which has low bioavailability and does not cross the BBB






14. This agent has greater affinity for muscarinic receptors and used for postoperative and neurogenic ileus and urinary retention






15. Initial DMARD of choice for patients with RA






16. Most common side effect of 1st generation antihistamines






17. Agent used for megaloblastic anemia (but does Not reverse neurologic symptoms) and decrease neural tube defects during pregnancy






18. Produces disulfiram - like reaction with ethanol






19. Alpha 1selective blockers






20. Site of action of thiazide diuretics






21. Only member of depolarizing neuromuscular blocker - causes fasciculation during induction and muscle pain after use; has short duration of action






22. Second generation sulfonylurea






23. Period of time of therapy after which GC therapy will need to be tapered






24. First generation sulfonylurea






25. What do beta cells in the pancreas produce?






26. Treatment for TB patients (think RIPE)






27. Names of three bisphosphonates available IV






28. Sulfonylurea Not recommended for elderly because of very long half life






29. MOA of nateglinide






30. Diuretic used to antagonize aldosterone receptors






31. Agent similar to cisplatin - less nephrotoxic - but greater myelosuppression






32. CCB with predominate effect on arteriole dilation






33. Agents that reduce heart rate - contractility - and O2 demand






34. MOA of general anesthetics






35. Vascular effects of metformin






36. Monitoring parameter to obtain before initiation of STATINS

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37. Selective Alpha 1 blocker used for hypertension - BPH - may cause first dose orthostatic hypotension






38. MOA of repaglinide






39. Most common SE of fibrates






40. Radio contrast media that inhibits the conversion of T4 to T3






41. Prevents thrombosis in patients with artificial heart valve






42. Adenosine's MOA






43. Inhaled anesthetics are myocardial depressants






44. Class of drugs with ability to decrease the maximal response to an agonist






45. Route of administration of warfarin






46. H1 blocker that is also a serotonin antagonist






47. Common SE of tamoxifen and raloxifene






48. Concentration in the plasma times (clearance divided by bioavailability)






49. Agent that is teratogen and causes a fetal syndrome






50. Cephalosporins able to cross the BBB