SUBJECTS
|
BROWSE
|
CAREER CENTER
|
POPULAR
|
JOIN
|
LOGIN
Business Skills
|
Soft Skills
|
Basic Literacy
|
Certifications
About
|
Help
|
Privacy
|
Terms
|
Email
Search
Test your basic knowledge |
USMLE/COMLEX Step 1 Pharmacology One Liners
Start Test
Study First
Subjects
:
health-sciences
,
usmle-step-1
,
comlex
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. SE of nitrates
Oxybutynin - dicyclomine
Steady state
Postural hypotension - reflex tachycardia - hot flashes - and throbbing headache due to meningeal artery dilation
Pentoxifylline
2. Longer acting benzodiazepines used in the management of withdrawal states of alcohol and other drugs
Glucocorticoids
Parathion
Terfenadine and astemizole (have been removed from the market)
Chlordiazepoxide and Diazepam
3. Enzyme that metabolizes acetaldehyde to acetate
Agranulocytosis
Beta - blockers such as propranolol
Aldehyde dehydrogenase
Bleomycin - vinca alkaloids - antimetabolites (eg. - 5- FU - 6- MP - methotrexate - etoposide)
4. Drug used for MRSA
Hallucinations resembling psychosis
Vancomycin
Adalimumab - infliximab and etanercept
Spironolactone
5. Antidepressant having stimulant effects similar to SSRI's and can increase blood pressure
Aplastic anemia and acute hepatic failure
Phenoxybenzamine
Venlafaxine
Cyclobenzaprine
6. Agent that is teratogen and causes a fetal syndrome
Olanzapine - aripiprazole - and sertindole
Lithium toxicity
Ketanserin cyproheptadine - and phenoxybenzamine
Ethanol
7. Mechanisms of action for Phenytoin - Carbamazepine - Lamotrigine
L- thyroxine (T4)
Sodium channel blockade
First order kinetics
Neostigmine
8. Antiarrhythmic effective in most types of arrhythmia
Entacapone and Tolcapone
Hallucinations resembling psychosis
Clopidogrel and ticlopidine
Amiodarone
9. Non - selective Alpha1blockers use to treat pheochromocytoma
Phenoxybenzamine
Ketamine
Diazepam
Inhibition of protein synthesis at the 50s subunit of ribosome
10. Moderate opioid agonists
Codeine - hydrocodone - and oxycodone
Phenobarbital
Cisplatin
Buspirone
11. Major SE of zileuton
Haloperidol or pimozide
Liver toxicity
TD50
Amitriptyline
12. Chelating agent used in Wilson's disease
Vasodilation
Penicillamine
Haloperidol or pimozide
Arteries and veins
13. SE of OCs
Lithium
Increased thromboembolic events
Glucagon
Raloxifene
14. W/D from this drug causes anxiety and mental discomfort
Metronidazole
Valproic acid
Nicotine
Pyridostigmine
15. Some side effects of corticosteroids
Hypertensive crisis
Osteopenia - impaired wound healing - inc. risk of infection - inc. appetite - HTN - edema - PUD - euphoria - psychosis - stria - thinning of skin
Nitrites
Yohimbine
16. Shock due to septicemia or myocardial infarction is made worse by
Increasing afterload and tissue perfusion declines
Dexrazoxane
Point mutation
Bromocriptine
17. SE of salicylates
Spironolactone
Zolpidem - zaleplon
Nicotine
Tinnitus - GI bleeding
18. Reason troglitazone was withdrawn from market
Nadolol
PTU
Seizures
Hepatic toxicity
19. Treatment of atropine overdose and glaucoma (because lipid soluable). Enters the CNS rapidly and has a stimulant effect - which may lead to convulsions
Physostigmine
Sulfasalazine
LD50
Kidneys
20. Used for Cushing's syndrome (increased corticosteroid)
Arginine
Dexamethasone suppression test
Benztropine
Calcium channels
21. MOA of nitrates
Ipratropium
Relax vascular smooth muscle - at low doses dilate veins and at high doses dilate arterioles
Ganciclovir - zidovudine - saquinavir - and interferon
Allopurinol
22. Opioids used in anesthesia
Hydroxychloroquine
Serum ammonia and LFT's
Osteopenia - impaired wound healing - inc. risk of infection - inc. appetite - HTN - edema - PUD - euphoria - psychosis - stria - thinning of skin
Morphine and fentanyl
23. Agent with long duration of action and is most likely to cause histamine release
Cardiac dysfunction - photosensitivity - skin (blue smurf syndrome) - Pulmonary fibrosis - thyroid and corneal deposits
high doses
Tubocurarine
Neuroleptanesthesia
24. COX 2 inhibitors should be used cautiously in pts with
Nesiritide (BNP)
Probenecid and sulfinpyrazone
Morphine and fentanyl
Pre - existing cardiac or renal disease
25. Regimen used for breast cancer
CMF (cyclophosphamide - methotrexate - and fluorouracil) and tamoxifen if ER+
Ketoralac
Penicillamine
Haloperidol or pimozide
26. Lactam that can be used in PCN allergic patients
Propranolol
Clozapine
Epinephrine - dipivefrin
Aztreonam
27. Inhibit angiotensin - converting enzyme (ACE)
Nefazodone
Neuroleptanesthesia
Tolerance
ACE inhibitors
28. These agents are used as antidiarrheal
Diphenoxylate - Loperamide
Pulmonary embolism and DVT
Minocycline
DUMBELSS (diarrhea - urination - miosis - bronchoconstriction - excitation of skeletal muscle and CNS - lacrimation - salivation - and sweating)
29. SE of thiazide (HCTZ) diuretics
Hyperuricemia - hypokalemia and hyperglycemia
Succinylcholine
Ondansetron - granisetron - dolasetron and alosetron
Allopurinol
30. Beta - blockers should be used cautiously in
L- thyroxine (T4)
Asthma (bronchospastic effects) - diabetes (block signs of hypoglycemia) and peripheral vascular disease
Sumatriptan - naratriptan - and rizatriptan
Finasteride (Proscar and Propecia respectively)
31. Arterial vasodilator that works by opening K+ channels
Allopurinol
Fluorocarbons and Industrial solvents
B- blockers
Minoxidil
32. Beta 1 agonist toxicity
Inhibits thyroid hormone synthesis by blocking iodination of the tyrosine residues of thyroglobulin
Neostigmine
Sinus tachycardia and serious arrhythmias
Sodium bicarbonate
33. Agent that is metabolized to acetaldehyde by alcohol dehydrogenase and microsomal ethanol - oxidizing system (MEOS)
Peripheral neuropathy (also excessive alcohol use is associated with HTN - anemia - and MI)
Ethanol
Amantadine
Iodide salts
34. Antibiotic causing red - man syndrome - and prevention
Clomiphene and tamoxifen
Dopamine
Sodium bicarbonate
Vancomycin - infusion at a slow rate and antihistamines
35. What do delta cells in the pancreas produce?
First generation due to being more lipid - soluble
Glucagon
Somatostatin
Alprazolam
36. Products of Phase II conjugation
Glucuronate - acetic acid - and glutathione sulfate
Warfarin (PT)
Administration of Vit. B6 (pyridoxine)
Cocaine
37. Side effect of sotalol
Aspirin
Valproic acid
prolongs QT and PR interval
Phenoxybenzamine
38. Nitrate used to prevent further attacks
Gynecomastia hyperkalemia - and impotence
Oral and transdermal forms of nitroglycerin
Cevimeline
Skeletal muscle tremor - tachycardia
39. Major route of elimination for Lithium
Albuterol
Presynaptic mu - delta - and kappa receptors
Kidneys
Epinephrine - dipivefrin
40. Used especially in postmenopausal women - dosage should be 1500 mg
increase the FREQUENCY of GABA- mediated chloride ion channel opening
Nonselective Muscarinic Antagonists
Calcium
Flatulence (do not use beano to tx) - diarrhea - abdominal cramps
41. GnRH antagonist with more immediate effects - used for infertility
Ganirelix
Pyridostigmine
Dextromethorphan - Codeine
B- blockers
42. SE of spironolactone
Phenoxybenzamine
Tinnitus - GI bleeding
Didanosine
Gynecomastia hyperkalemia - and impotence
43. Pyrimidine analog that causes 'Thymine - less death' given with leucovorin rescue
Lepirudin
Postsynaptic Mu receptors
Calcitonin (salmon prep)
5- flouracil (5- FU)
44. Common toxicities of cisplatin
Oxybutynin - dicyclomine
Testicular cancer
Mirtazapine
Nephro and ototoxicity
45. Drug used for African sleeping sickness
L- asparaginase
Suramin
Benzodiazepine receptor BZ1 (although do not have a benzodiazepine ring structure)
Tetracycline
46. Drug used in ergot alkaloids overdose - ischemia and gangrene
Reduce aqueous secretion
Hepatic
Nitroprusside
Liver toxicity - increased serum cholesterol
47. First generation sulfonylurea
Methicillin - nafcillin - and dicloxacillin
Ipratropium
Mirtazapine
Chlorpropamide - tolbutamide - tolazamide - etc.
48. Treatment for opioid addiction
Long acting cholinesterase inhibitors
Methadone - followed by slow dose reduction
Alkalinize urine - dialysis
Morphine and fentanyl
49. Agent used in CHF that is a selective alpha and nonselective beta blocker
sulfamethoxazole/ trimethoprim
Carvedilol
Sinus tachycardia and serious arrhythmias
Na+/K+ exchange
50. SE of phenytoin
Sotalol
Arginine
Gingival hyperplasia - nystagmus - diplopia and ataxia
Affinity
Sorry!:) No result found.
Can you answer 50 questions in 15 minutes?
Let me suggest you:
Browse all subjects
Browse all tests
Most popular tests
Major Subjects
Tests & Exams
AP
CLEP
DSST
GRE
SAT
GMAT
Certifications
CISSP go to https://www.isc2.org/
PMP
ITIL
RHCE
MCTS
More...
IT Skills
Android Programming
Data Modeling
Objective C Programming
Basic Python Programming
Adobe Illustrator
More...
Business Skills
Advertising Techniques
Business Accounting Basics
Business Strategy
Human Resource Management
Marketing Basics
More...
Soft Skills
Body Language
People Skills
Public Speaking
Persuasion
Job Hunting And Resumes
More...
Vocabulary
GRE Vocab
SAT Vocab
TOEFL Essential Vocab
Basic English Words For All
Global Words You Should Know
Business English
More...
Languages
AP German Vocab
AP Latin Vocab
SAT Subject Test: French
Italian Survival
Norwegian Survival
More...
Engineering
Audio Engineering
Computer Science Engineering
Aerospace Engineering
Chemical Engineering
Structural Engineering
More...
Health Sciences
Basic Nursing Skills
Health Science Language Fundamentals
Veterinary Technology Medical Language
Cardiology
Clinical Surgery
More...
English
Grammar Fundamentals
Literary And Rhetorical Vocab
Elements Of Style Vocab
Introduction To English Major
Complete Advanced Sentences
Literature
Homonyms
More...
Math
Algebra Formulas
Basic Arithmetic: Measurements
Metric Conversions
Geometric Properties
Important Math Facts
Number Sense Vocab
Business Math
More...
Other Major Subjects
Science
Economics
History
Law
Performing-arts
Cooking
Logic & Reasoning
Trivia
Browse all subjects
Browse all tests
Most popular tests