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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Alpha agonist used to produce mydriasis and reduce conjunctival itching and congestion caused by irritation or allergy - it does not cause cycloplegia






2. Antidepressant having stimulant effects similar to SSRI's and can increase blood pressure






3. MOA of penicillin






4. MOA for Ethosuximide






5. COX 2 inhibitors may have reduced risk of






6. Anticoagulant of choice in pregnancy






7. This may antagonize activity of local anesthetics






8. MOA of class I A (eg. Procainamide) - class IB (eg. Lidocaine) - and class IC (eg. Flecainide) antiarrhythmics






9. Antidote to benzodiazepine overdose (antagonist that reverses the CNS effects)






10. SE of penicillamine






11. Opioid antagonist that is given IV and had short DOA






12. Overdoses of this agent with powerful vasoconstrictive action may result in fatalities from arrhythmias - seizures - respiratory depression - or severe HTN (MI and stroke)

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13. Toxicity caused by nitroprusside and treatment






14. Drug is used with testosterone for male fertility






15. Agent used in drug therapy of Parkinson's instead of Dopamine which has low bioavailability and does not cross the BBB






16. Anti - seizure agent that exhibits non - linear metabolism - highly protein bound - causes fetal hydantoin syndrome - and stimulates hepatic metabolism






17. HIV antiviral class known to have severe drug interactions by causing inhibition of metabolism






18. 1st generation antihistamine that is least sedating






19. MOA of nateglinide






20. LA causing methemoglobinemia






21. Nonselective alpha - blocking drug - short acting and reversible - used for rebound HTN from rapid clonidine withdrawal - and Raynaud's phenomena






22. Agent that is a partial agonist for the 5- HT1A receptor






23. MOA of nesiritide






24. Block glycoprotein IIb/IIIa involved in platelet cross - linking






25. Used for SIADH






26. Acetaminophen only has






27. SE of Aspirin






28. ACTH analog used for diagnosis of patients with corticosteroid abnormality






29. Most important potential SE of metformin






30. Common toxicities of cisplatin






31. SE of Thiazolindinediones






32. Anti - androgen used for prostate cancer






33. Exogenous insulin contains






34. Lethal arrhythmias resulting from concurrent therapy with azole fungals (metabolized by CYP 3A4) and these antihistamines which inhibit the 3A4 iso - enzyme.






35. SE of INH






36. State of analgesia and amnesia produced when fentanyl is used with droperidol and nitrous oxide






37. Toxicity of anticholinergics






38. Agent used in the treatment of alcoholism - if alcohol is consumed concurrently - acetaldehyde builds up and results in nausea - headache - flushing - and hypotension






39. Reversal of blockade by neuromuscular blockers






40. Digoxin toxicity can be precipitated by






41. Atropine fever is the most dangerous effect and can be lethal in this population group






42. Antidepressant also used for sleep that causes priapism






43. Window between therapeutic effect and toxic effect






44. Antidote used for organophosphate/anticholinesterase poisoning






45. DOC for malignant hyperthermia by acting on the sacroplasmic reticulum or skeletal muscle






46. Osmotic diuretic used to treat increased intracranial pressure






47. Prevents thrombosis in patients with artificial heart valve






48. Blows DNA (breaks DNA strands) - limiting SE is pulmonary fibrosis






49. Specific pharmacokinetic characteristic of amiodarone






50. Thiazolidinediones