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USMLE/COMLEX Step 1 Pharmacology One Liners

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Class of drugs that may cause cross - sensitivity with thiazide diuretics






2. Agent that inhibits hepatic metabolism - is hepatotoxic and teratogen that can cause neural tube defects and gastrointestinal distress






3. One depolarizing blocker that causes continuous depolarization and results in muscle relaxation and paralysis - causes muscle pain postoperatively and myoglobinuria may occur






4. Anti - seizure drugs used also for pain of neuropathic orgin






5. These agents are CNS depressants






6. IV barbiturate used as a pre - op anesthetic






7. Tolerance to all effects of opioid agonists can develop except






8. H2 blocker that causes the most interactions with other drugs






9. Anticoagulant of choice in pregnancy






10. Example of three antidepressants that are indicated for obsessive compulsive disorder






11. Drugs available in combination with metformin






12. SE for Felbamate






13. Antidote used in poisonings: copper (Wilson's disease) - lead - mercury - and arsenic






14. Drug used supraventricular arrhythmias






15. Syndrome of hypersecretion of gastric acid and pepsin usually caused by gastrinoma; it is associated with severe peptic ulceration and diarrhea






16. Toxic to the liver - kidney - lungs - bone marrow - peripheral nerves - and cause brain damage in animals - sudden death has occurred following inhalation






17. Rate limiting step of alcohol metabolism






18. A hormone whose mechanism of action (MOA) utilizes intracellular receptors






19. Alpha 1 agonist toxicity






20. Removal of PCP may be aided






21. SE of Aspirin






22. Agent effective in physiologic and essential tremor






23. Organophosphate anthelmintic agent with long DOA






24. Another pneumonic for anticholinergic toxicity

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25. The most common type of drug interaction of sedative hypnotics with other depressant medications






26. This diuretic decreases aqueous secretion due to lack of HCO3- ion. Causes drowsiness and paresthesias - alkalinization of the urine may precipitate calcium salts - hypokalemia - acidosis






27. Opioids used in anesthesia






28. Most inhaled anesthetics SE






29. Important in synthesis of glucose to glycogen in the liver






30. Toxicity of amphotericin






31. Antidote for acetaminophen toxicity






32. NSAID also available as an ophthalmic preparation






33. Mediator of tissue pain - edema - inactivated by ACE - and may be a contributing factor to the development of angioedema






34. Drugs of choice for status epilepticus






35. Partial opioid agonist - considered a strong analgesic - has a long duration of action and is resistant to naloxone reversal






36. Major SE of bisphosphonates






37. MOA for Ethosuximide






38. System that increases in activity with chronic ethanol exposure and may contribute to tolerance






39. Drug that causes contraction of the uterus






40. Heterocyclic antidepressants least likely to affect sexual performance - used for management of nicotine withdrawal - SE's include dizziness - dry mouth - aggravation of psychosis - and seizures






41. MAOI should not be administered with SSRI's or potent TCA's due to development of this condition






42. Antidote for salicylate intoxication






43. Class III antiarrhythmic that exhibits properties of all 4 classes






44. Alpha 1selective blockers






45. Approved for use in severe pulmonary HTN






46. Difference between COX 1 and COX 2






47. Agent that is a partial agonist for the 5- HT1A receptor






48. TCA used in chronic pain - a hypnotic - and has marked antimuscarinic effects






49. DOC for status epilepticus






50. Nonselective alpha - blocking drug - long acting and irreversible - and used to treat pheochromocytoma. Blocks 5- HT - so occasionaly used for carcinoid tumor. Blocks H1 and used in mastocytosis