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Test your basic knowledge |
USMLE Embryo
Start Test
Study First
Subjects
:
health-sciences
,
usmle
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Cleft palate is a failure of fusion of the lateral palatine processes - the nasal septum and or the ________?
Glans penis and corpus cavernosum and spongiosum; glans clitoris and vestibular bulbs
Medial palatine processes
blood entering the RA
Decreased separation of hemispheres across midline; cyclopia
2. what else is the caudal regression known as? What two teratogen can cause this in the fetus?
VACTERL; OCPs and maternal diabetes
Decreases
...
4th pouch
3. What axis does the basal plate form? what neural system does it become?
Ampulla
Ventral shaft of penis (penile urethra); labia minora
Yolk sac; 3rd week
Ventral ; motor
4. What connects the thyroid to the tongue? when happens if it doesnt obliterate?
Thyroglossal duct; persists as pyramidal lobe of thyroid; foramen cecum on tongue is normal remnant of thyroglossal duct
Allantois
Metencephalon; cerebellum
Ventral bud
5. Which branchial derivative accounts for the sensation and taste in the posterior 2/3 of the tongue? how about the very back?
4th arch; 6th arch
Neural plate; closes by week 4
1st branchial arch
Week 4
6. In anencephaly you see...
elevated AFP
Polyhydramnios
Neuroectoderm
Palpable olive mass in epigastric region; nonbilious projectile vomitting @around 2 weeks
7. What hormone is hcG structurally similar too?
LH
Thyroglossal duct cysts will move with swallowing while persistent cervical sinuses in lateral neck wont
During; instrinsic
Before getting pregnant!
8. What role does the placenta have?
6-30
Nutrient and gas exchange
1st
Week 8
9. From What embryonic layer is the eustachian tube from?
Mesoderm
mesodermal
Persistance of herniation of abdominal contents into umbilical cord covered by peritoneum; 13 - 18
Initial left to right shunting - then switches
10. What is the neural plate and From what does it form?
Ectoderm
Rhombencephalon
Nicotine; preterm labor
Failure of the urachus to obliterate; outpouching of the bladder
11. What is the effect of teratogens before week 3?
VACTERL; OCPs and maternal diabetes
Failure to recanalize; 21
All or none
Neural crest cells
12. What is contained in the umbilical cord?
Umbilical artery - vein; and whartons jelly (mucus connective tissue) - urachus
DES
Excessive resorption of septum primum or secondum (or both)
Endocardial cushions
13. From What embryonic layer does bone of the skulls arise?
Endocardial cushions
Mesoderm
Neural crest cells
elevated AFP
14. From What embryonic layer is the bladder and urethra from?
80%
VSD
DHT; estrogen
Mesoderm
15. From what aortic arch does the stapedial artery arise? the hyoid?
Hypertrophy of muscularis externis of pylorus; surgical incision
2nd; 2nd
Thalidomide; nausea
Rhombencephalon
16. Which branchial derivative accounts for the posterior 2/3 of the tongue?
Neuroectoderm
Incomplete; yes
3rd and 4th arches
Foramen cecum and terminal sulus
17. From What embryonic layer does the adenohypophysis arise?
Neuroectoderm
Neural crest cells
Respiratory distress syndrome
Surface ectoderm
18. What causes urine discharge from the umbilicus?
Neural crest cells
is no longer intact
Failure of the urachus to obliterate
hypertrophy
19. From What embryonic layer do the parafollicular cells of the thyroid arise?
Embryonic period; 1st trimester
Cleft lip/palate
Maxillary
Neural crest cells
20. What is a zygote?
Sperm plus egg
Surface ectoderm
Aortic arch and prox part of subclavian
Surface ectoderm
21. From where is the pancreas derived? the spleen?
Prostaglandins
Mesoderm
Foregut; dorsal mesentery (mesodermal)
Partial closure of vitelline duct so that the patent portion is attached to ileum; ectopic gastric mucosa; melena and periumbilical pain
22. From What embryonic layer are the schwann cells from ?
3rd pouch
Myelencephalon
Post. sup wall; luteal phase
Neural crest cells
23. What are two common findings in pyloric stenosis?
No more umbilical circulation emptying into RA
Hypospadias
Palpable olive mass in epigastric region; nonbilious projectile vomitting @around 2 weeks
Muscles of Mastication: Temporalis - masseter - Lateral and Medila pterygoids - Mylohyoid - anterior belly of the digastric - tensor tympani - tensor veli palatini; ant 2/3 of tongue
24. What three layers form during gastrulation? From What do they form? and what week does gastrulation occur?
Ectoderm - mesoderm - endoderm; epiblast - primitive streak - hypoblast; week 3
Prosencephalon
pyloric stenosis
Grooves/clefts; arches; pouches
25. What teratogen can cause vaginal clear cell adenocarcinoma in the fetus?
Congenital and chromosomal abnormalities
Endocardial cushions
Rostral fold closure ; lateral fold closure; lateral fold closure; caudal fold closure
DES
26. How does annular pancreas present in children?
Gastric outlet obstruction (bilious vomiting - feeding intolerance - abdominal distention)
Ring of pancreatic tissue can cause duodenal narrowing; ventral pancreatic bud abnormally encircles 2nd part of duodenum
Tongue
Neural crest migration - they then cause spiral
27. Name two endocardial cushion defects.
Ebsteins anomaly; tricuspid atresia
Lots - cleft palate/lip
20-50yrs - Abdominal pain - Postprandial fullness - Nausea - Peptic ulcers - Pancreatitis - Rarely - biliary obstruction
First branchial pouch
28. What is the mnueomonic for the mesodermal defects? What does it stand for?
Failure of bony spinal canal to fuse; no; lower vertebral levels
Ventral bud
6-30
VACTERL- vertebral defect - anal atresia - cardiac defects - tracheo - esophageal fistula - renal defects - limb defects
29. what week do the genitalia start to have male/female characteristics? What trimester is that?
Rhombencephalon
Dorsal and ventral buds
Urachus/median umbilical ligament; bladder and yolk sac
Week 10-12; end of 1st trimester
30. Which branchial derivative accounts for taste in the ant 2/3?
80%
Epiblast
Branchial arch 2
3
31. what closes the ductus arteriousus?
Increase in oxygen concentration which decreases prostaglandin concentration
A vitelline fistula - failure of vitelline duct to close
Urogenital sinus; wolffian duct; mullerian duct; urogenital sinus; wolffian duct; wolffian duct; mullerian; mullerian
Endoderm
32. What artery is derived branchial (aortic) arch 6?
Incomplete fusion of paramesonephric ducts; UT abnormalities and infertility
Endoderm lined structures of ear: middle ear cavity - eustacian tube - mastoid air cells
Failure of the urachus to obliterate; outpouching of the bladder
Pulm art (prox) and ductus arteriosus
33. what bone/cartilage and nerves are derived from branchial arch 1?
Outgrowth of mesonephric as ureteric bud; most caudal
Surface ectoderm
Meckels cartilage: mandible - malleus - INCUS - sphenoMandibular ligament; CN V2 and V3
When the AP septum meets and fuses with the muscular ventricular septum to form membranous intraventricular septum - closing interventricular foramen
34. From where does the signal come from to suppress paramesonephric ducts? what stimulates development of the mesonephric ducts?
Ring of pancreatic tissue can cause duodenal narrowing; ventral pancreatic bud abnormally encircles 2nd part of duodenum
Mullerian inhibitory factor from Sertoli cells; increased androgen from Leydig cells
Ebsteins anomaly; tricuspid atresia
Week 4
35. What two things cause VACTERL syndrome?
28 week onward
Ectoderm
OCPS and maternal diabetes
SRY gene on Y chromosomes; sertoli and leydi; MIF and androgens; suppression of paramesonephric ducts and dev. of mesonephric (all respectively)
36. How do AV canals form?
Neural crest cells
Week 8
From endocardial cushions (ventral and dorsal meet each other)
Nicotine; preterm labor
37. What is meckel's diverticulum? What is it associated with? What does that cause?
Partial closure of vitelline duct so that the patent portion is attached to ileum; ectopic gastric mucosa; melena and periumbilical pain
Midgut; 10th week
Mid gut to yolk sac; omphalomesenteric duct; 7th week
Week 3-8
38. From What embryonic layer are the cardiovascular - lymphatics and blood from?
Neuroectoderm
VACTERL; OCPs and maternal diabetes
Lots - cleft palate/lip
Mesoderm
39. What is an example of a syndrome that can cause abnormal neural crest migration and thus CV abnormalities?
Urogenital sinus; wolffian duct; mullerian duct; urogenital sinus; wolffian duct; wolffian duct; mullerian; mullerian
DiGeorge
1st arch neural crest fails to migrate --> mandibular hypoplasia - facial abnormalities (cleft palate - decreased slanting of palpebral fissures)
Surface ectoderm
40. what invaginates to form the primitive streak?
Epiblast
Endoderm
1st branchial arch
Decreased pulmonary resistance in the pulmonary vasculature
41. What are the neural crest cells and where do they come form? where do they go?
8
4th week
Apical ectodermal ridge; limb lengthening; stimulates mitosis of underlying mesoderm
They are the edge of neural plate folding; all over the body
42. What artery is derived branchial (aortic) arch 1?
Truncus arteriosus; pulmonary trunk
Maxillary
Mesoderm
LH
43. From What embryonic layer do CNS neurons arise?
Hemorrhage - bone deformities
Epiblast
Neuroectoderm
blood entering the RA
44. Blood coming in the umbilical vein is ____ saturated
3 -4 -6
80%
4th pouch
Dorsal and ventral buds
45. From where does the permanent kidney for? is it most caudal or most cranial?
pyloric stenosis
Outgrowth of mesonephric as ureteric bud; most caudal
Muscular ventricular septum; no
SRY gene on Y chromosomes; sertoli and leydi; MIF and androgens; suppression of paramesonephric ducts and dev. of mesonephric (all respectively)
46. What embryological structure gives rise to the coronary sinus?
Left horn of the sinus venosus
Blind upper esophagus with lower esophagus connected to trachea; cyanosis - choking and vomiting with feeding; air bubble on CXR; polyhydramnios; failure to pass NG tube; pneumonitis
Prostaglandins
Rostral fold closure ; lateral fold closure; lateral fold closure; caudal fold closure
47. What is the 'fetal period'- ie When is it?
Week 8
Most pharyngeal constrictors - Cricothyroid - levator veli palatini; CN X (superior laryngeal branch - swallowing)
Week 2; bilaminar disk; epiblast and hypoblast
Right horn of the SV
48. What is jejunal - ileal - colonic atresia usually due to? What do you see on x ray?
When left to right shunting switching to right to left shunting
Vascular accident intra uterine; apple peel atresia
Lots - cleft palate/lip
Mesonephros; male genital system
49. From What embryonic layer does the epidermis arise?
Neural crest cells
80%
Surface ectoderm
Failure to spiral (aorta coming out of RV and PA coming out of left ventricle)- two completely separate systems
50. To what germ layer does the branchial pouches correlate to?
Neuroectoderm
Thalidomide; nausea
Umbilical artery - vein; and whartons jelly (mucus connective tissue) - urachus
Endoderm