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Test your basic knowledge |
USMLE Embryo
Start Test
Study First
Subjects
:
health-sciences
,
usmle
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What embryological structure gives rise to the trabeculated part of the left and right atrium?
Week 4
Primitive atrium
Absent cerebellar vermis; cystic enlargement of 4th ventricle
Prosencephalon - mesencephalon - rhombencephalon
2. What causes a patent foramen ovale?
Prenatal and perinatal
Week 2; bilaminar disk; epiblast and hypoblast
Excessive resorption of septum primum or secondum (or both)
Mesoderm
3. What is the Eisenmeger complex?
Respiratory distress syndrome
Neuroectoderm
No more umbilical circulation emptying into RA
When left to right shunting switching to right to left shunting
4. What hormone is hcG structurally similar too?
3 -4 -6
Endoderm
Grooves/clefts; arches; pouches
LH
5. What teratogens can cause renal damage in the fetus?
Neural crest cells
ACE inhibitors - HCTZ
Ectoderm; endoderm
Increase in oxygen concentration which decreases prostaglandin concentration
6. What are the two walls of the prosencephalon and What do they become?
Dorsal and ventral buds
Endocardial cushions
Gastric outlet obstruction (bilious vomiting - feeding intolerance - abdominal distention)
Cerebral hemisphere - thalami
7. What components do the neural crest cells of the branchial arches give rise to?
Bones - cartilage - and nerves
Folate antagonists
Ring of pancreatic tissue can cause duodenal narrowing; ventral pancreatic bud abnormally encircles 2nd part of duodenum
Turners; inferior
8. What do membranous interventricular septal defect cause? What does this lead to?
2nd pouch
Stapedius and hyoid artery
Initial left to right shunting - then switches
V3; VII
9. What secretes hCG?
Neural crest cells
Synctiotrophoblast
Week 3-8
Week 4; week 3
10. Where is erythropoeisis in the weeks 3-8 of fetal development? Where does it occur after that? until when?
Neural crest cells
Yolk sac; liver (weeks 6-30) and spleen (9-28 weeks)
Week 3; primitive streak formation from the epiblast makes the three layers
Fallopian tube - uterus - upper 1/3 of vagina
11. What does the midgut form? hindgut?
Membrane - all 3 from 1st appartus
Duodenum to transverse colon; distal transverse colon to rectum
Fluid filled cavity in spinal cord; C8- T1; arnold chiari II
Week 3-8
12. From what germ layer does the primitive heart tube arise?
Mesoderm
Muscular ventricular septum; no
Persistance of herniation of abdominal contents into umbilical cord covered by peritoneum; 13 - 18
Germinal matrix hemorrhage
13. What are the clinical symptoms that present with syringomelia?
Epispadias
Bilateral loss of pain and temperature sensation in upper extremities with preservation of touch sensation
Caused by compression on trocheal nerve - causes vertical gaze paralysis (associated with arnold chiari)
Endometrium
14. From What embryonic layer does the neurohypophysis arise?
A vitelline fistula - failure of vitelline duct to close
Aortic arch and prox part of subclavian
Neuroectoderm
1st
15. From What embryonic layer are the dorsal root and celiac ganglion from?
4th pouch
Lithium
Endoderm
Neural crest cells
16. Does malformation occur during or after the embryonic period? is it due to an extrinsic or intrinsic disruption?
Valproate acid
During; instrinsic
Maxillary
Fallopian tube - uterus - upper 1/3 of vagina
17. What does the ductus venosus shunt blood away from? What is its remnant?
Hemorrhage - bone deformities
Hepatic circulation; ligamentum venosum
Persistent connection between amniotic cavity and spinal canal; low folic acid
Aminoglycosides
18. What is the difference between agenesis and aplasia?
Dorsal; faulty positioning of genital tubercle
Neuroectoderm
Primitive ventricle
No organ in each; agenesis no primordial tissue
19. what muscles are derived from branchial arch 6? CN?
All intrinsic muscles of larynx except cricothyroid; CN X (recurrent laryngeal nerve - speaking)
Ventral ; motor
Mesoderm
Apical ectodermal ridge
20. From What embryonic layer does the lens of the eye arise?
First branchial pouch
Surface ectoderm
hypertrophy
lumbosacral
21. What causes the increase in left atrial pressure to close the fossa ovale?
Temporary cervical sinus
Thyroglossal duct cysts will move with swallowing while persistent cervical sinuses in lateral neck wont
Decreased separation of hemispheres across midline; cyclopia
Decreased pulmonary resistance in the pulmonary vasculature
22. What embryological structures give rise to the SVC?
Right common cardinal vein and right anterior cardinal vein
Synctiotrophoblast; outer; no
4th pouch
Hypertrophy of muscularis externis of pylorus; surgical incision
23. By what week is the neural tube supposed to be closed? when did it start forming?
Fluid filled cavity in spinal cord; C8- T1; arnold chiari II
SRY gene on Y chromosomes; sertoli and leydi; MIF and androgens; suppression of paramesonephric ducts and dev. of mesonephric (all respectively)
Physiologic incomplete muscular ventricular septum
Week 4; week 3
24. failure to close of what fold results in sternal defects? omphalocele? gastrochisis? bladder extrosphy?
Decreases
Ectoderm
Rostral fold closure ; lateral fold closure; lateral fold closure; caudal fold closure
Mesoderm
25. What does the maternal component of the placenta provide? Where is it derived from?
Foramen cecum and terminal sulus
Nutrient and gas for exchange; endometrium
Cerebral hemisphere - thalami
Week 4
26. what closes the interventricular foramen?
Physiologic incomplete muscular ventricular septum
monoamniotic
Neural crest development; MEN 2A (pheo - PTH tumor - parafollicular cell tumor)
Mesoderm
27. From where does the medulla form?
Muscles of facial expression - stapedius - stylohyoid - posterior belly of the digastric
Hemorrhage - bone deformities
When left to right shunting switching to right to left shunting
Myelencephalon
28. From What embryonic layer does the sensory organs of the ear arise?
Surface ectoderm
Rostral fold closure ; lateral fold closure; lateral fold closure; caudal fold closure
Dorsal; faulty positioning of genital tubercle
Palpable olive mass in epigastric region; nonbilious projectile vomitting @around 2 weeks
29. What teratogens can cause CN VIII toxicity in the fetus?
Tunica vaginalis not fully fused
Aminoglycosides
Mesoderm
6th aortic arch
30. From What embryonic layer do CNS neurons arise?
Caused by compression on trocheal nerve - causes vertical gaze paralysis (associated with arnold chiari)
Dorsal ventral axis
Neuroectoderm
Scrotum; labia majora
31. Which arches form the posterior 1/3 of the tongue?
Arches 3 and 4
No more umbilical circulation emptying into RA
Aortic arch and prox part of subclavian
Ectoderm
32. What does DHT turn the labioscrotal swelling into? estrogen?
Week 4; week 3
Persistence of 3rd cleft (groove) and pouch causes fistula between tonsillar area and cleft in lateral neck
Scrotum; labia majora
Mesoderm
33. What layer is the epiblast? hypoblast?
Amniotic epithelium
Ectoderm; endoderm
They are the edge of neural plate folding; all over the body
Prostaglandins
34. When does erythropoeisis begin in the bone marow?
28 week onward
Neuroectoderm
Fallopian tube - uterus - upper 1/3 of vagina
Failure of the urachus to obliterate; outpouching of the bladder
35. The spinal cord is made from...
Surface ectoderm
Dorsal and ventral buds
T neuroectoderm
Surface ectoderm
36. What artery is derived branchial (aortic) arch 4?
Aortic arch and prox part of subclavian
Prevent recurrent UTIs
VACTERL- vertebral defect - anal atresia - cardiac defects - tracheo - esophageal fistula - renal defects - limb defects
Surface ectoderm
37. From where is the pancreas derived? the spleen?
Rhombencephalon
Bulbos Cordis; right ventricle entirely
Endoderm
Foregut; dorsal mesentery (mesodermal)
38. Where is the most common ectopic thyroid tissue?
3rd pouch
...
Tongue
Ventral shaft of penis (penile urethra); labia minora
39. From What embryonic layer do the parafollicular cells of the thyroid arise?
Arnold chiari; syringomyelia
Week 3; primitive streak formation from the epiblast makes the three layers
Neural crest cells
Surface ectoderm
40. From What embryonic layer does bone arise ?
From teh lung;blood from IVC in RA to LA; fossa ovalis
Neuroectoderm
Metencephalon; cerebellum
Mesoderm
41. What is the female remnant of processus vaginalis? male remnant?
Rostral fold closure ; lateral fold closure; lateral fold closure; caudal fold closure
All 3
Obliterated; forms tunica vaginalis
mesodermal
42. What is another name for the mesonephric duct? paramesonephric?
Wolffian; mullerian
arnold chiari associated with thoraclumbar myelomeningocele
Amniotic epithelium
Neural crest cells
43. What embryological structure gives rise to the coronary sinus?
Week 8
Left horn of the sinus venosus
No more umbilical circulation emptying into RA
Surface ectoderm
44. What are the three regions of the brain (in order of cranial to caudal)?
Surface ectoderm
Prosencephalon - mesencephalon - rhombencephalon
2; 1
Female; paramesonephric; mesonephric
45. What is the mcc of renovascular hypertension in children? What does this predispose to?
Week 4; week 3
3
Renal artery stenosis;
Synctiotrophoblast
46. To what germ layer does the branchial pouches correlate to?
Stapedius and hyoid artery
Thyroglossal duct; persists as pyramidal lobe of thyroid; foramen cecum on tongue is normal remnant of thyroglossal duct
Deformation
Endoderm
47. What teratogens can cause flipper limbs (limb defects)? What is this drug used for?
mesoderm
Thalidomide; nausea
Bilateral loss of pain and temperature sensation in upper extremities with preservation of touch sensation
Day 6; with implantation
48. Where is the mothers blood located in the placenta?
Lacunae in between the chorionic villi
Branchial arch 2
Yolk sac; liver (weeks 6-30) and spleen (9-28 weeks)
Found in lateral neck; from no obliteration of 2-4th clefts
49. From What embryonic layer do the ANS arise?
Neural crest cells
Neuroectoderm
Blastocyst; epiblast and hypoblast; synctiotrophoblast and cytotrophoblast
Obliterated; forms tunica vaginalis
50. What is the most common subtype of tracheoesophageal fistula? name some symptoms (hint: O2 levels - feeding - stomach on CXR - - amnios? - NG tube? - respiratory infection? )
VACTERL- vertebral defect - anal atresia - cardiac defects - tracheo - esophageal fistula - renal defects - limb defects
Persistent connection between amniotic cavity and spinal canal; low folic acid
Bones - cartilage - and nerves
Blind upper esophagus with lower esophagus connected to trachea; cyanosis - choking and vomiting with feeding; air bubble on CXR; polyhydramnios; failure to pass NG tube; pneumonitis