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Test your basic knowledge |
USMLE Embryo
Start Test
Study First
Subjects
:
health-sciences
,
usmle
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. What embryological structure gives rise to the trabeculated part of the left and right atrium?
Neuroectoderm
Urogenital sinus; wolffian duct; mullerian duct; urogenital sinus; wolffian duct; wolffian duct; mullerian; mullerian
Muscular ventricular septum; no
Primitive atrium
2. What does the ductus arteriosus shunt blood away from - to where? What is its remnant?
Endoderm
Ectoderm; endoderm
From the the lung; blood from SVC that went into RV gets shunted from pulm artery to aorta; ligamentum arteriosum
Week 8
3. From what aortic arch does the first part of the maxillary artery arise?
1st
Cytotrophoblast and synctiotrophoblast
V3; VII
Fluid filled syrinx causes expansion and degeneration of cord tracts
4. What is associated with only one umbilical artery?
Congenital and chromosomal abnormalities
Maxillary and medial nasal processes
Surface ectoderm
Mesoderm
5. How is amniontic fluid excreted? How is amniotic fluid resorped?
is no longer intact
Fetal kidney; fetal swallows - absorbs - and then removed from placental blood
Indomethacin; blocks PG production
Germinal matrix hemorrhage
6. From What embryonic layer does the gut tube epithelium arise?
Tetracyclines
External auditory meatus
Endoderm
1st arch neural crest fails to migrate --> mandibular hypoplasia - facial abnormalities (cleft palate - decreased slanting of palpebral fissures)
7. When does the blastocyst split into two disks? What is this disk called? What are the two germ layers called?
LH
Mesdoerm
Cleft lip/palate
Week 2; bilaminar disk; epiblast and hypoblast
8. What axis is Wnt 7 responsible for developing?
All or none
Dorsal ventral axis
4th pouch
VSD
9. What can vit A in excess cause in the fetus?
Thickened ectoderm at end of each developing limb
Neural crest migration - they then cause spiral
20-50yrs - Abdominal pain - Postprandial fullness - Nausea - Peptic ulcers - Pancreatitis - Rarely - biliary obstruction
Lots - cleft palate/lip
10. What is the primitive streak? From what layer does it form?
Upper 1/3; urogenital sinus
Most pharyngeal constrictors - Cricothyroid - levator veli palatini; CN X (superior laryngeal branch - swallowing)
arnold chiari associated with thoraclumbar myelomeningocele
Mesoderm; epiblast
11. When does hcG get secreted? What does it do?up until when ?
OCPS and maternal diabetes
Surface ectoderm
Day 6; maintains corpus luteum; 1st trimester
Week 3; primitive streak formation from the epiblast makes the three layers
12. What does DHT turn the urogenital folds into? estrogen?
A vitelline fistula - failure of vitelline duct to close
Neural crest migration - they then cause spiral
Cerebral hemisphere - thalami
Ventral shaft of penis (penile urethra); labia minora
13. During what months is the fetus most susceptible to teratogens? What trimester?
Endoderm lined structures of ear: middle ear cavity - eustacian tube - mastoid air cells
Lots - cleft palate/lip
Embryonic period; 1st trimester
Apical ectodermal ridge
14. what bone/cartilage and nerves are derived from branchial arch 3?
VSD
Increase in oxygen concentration which decreases prostaglandin concentration
Thyroid - cricoid - arytenoids - corniculate cuneiform
Greater horn of hyoid; CN IX (styloPharyngeus)
15. From what region do the thalami form?
Diencephalon
Urogenital sinus; wolffian duct; mullerian duct; urogenital sinus; wolffian duct; wolffian duct; mullerian; mullerian
Neural crest cells
Ventral shaft of penis (penile urethra); labia minora
16. From What embryonic layer does the oligodendrocytes arise?
Week 3-8
Neuroectoderm
DiGeorge
Transposition of great vessels (failure to spiral)- right to left shunt; tetralogy of Fallout (right to left shunt caused by skewed development of septum); persistent TA (partial septum development - also right to left shunt)
17. What trisomy is associated with holoprosencephaly? What teratogen?
Primitive ventricle
Bilateral loss of pain and temperature sensation in upper extremities with preservation of touch sensation
Muscular ventricular septum; no
Pataus; fetal alcohol syndrome
18. From What embryonic layer does the brain arise?
They are the edge of neural plate folding; all over the body
Prenatal and perinatal
Neuroectoderm
Persistent connection between amniotic cavity and spinal canal; low folic acid
19. From which myotomes are muscles of the tongue derived from?
Bones - cartilage - and nerves
Occiptal
Mesoderm
Rostral fold closure ; lateral fold closure; lateral fold closure; caudal fold closure
20. What teratogens can cause discolored teeth?
Tetracyclines
Endometrium
...
3
21. What is an arnold chiari II malformation? through what hole does it herniate?
T neuroectoderm
IX; X
Cerebellar tonsillar herniation through foramen magnum
Umbilical artery - vein; and whartons jelly (mucus connective tissue) - urachus
22. Which branchial apparatus makes the external auditory meatus?
Urachus/median umbilical ligament; bladder and yolk sac
Week 8
Neuroectoderm
1st cleft/groove (Ectoderm)
23. Where is erythropoeisis in the weeks 3-8 of fetal development? Where does it occur after that? until when?
Yolk sac; liver (weeks 6-30) and spleen (9-28 weeks)
20-50yrs - Abdominal pain - Postprandial fullness - Nausea - Peptic ulcers - Pancreatitis - Rarely - biliary obstruction
Fluid filled cavity in spinal cord; C8- T1; arnold chiari II
Hepatic circulation; ligamentum venosum
24. What is the Eisenmeger complex?
Prosencephalon
3rd pouch
When left to right shunting switching to right to left shunting
Neuroectoderm
25. What is hypoplasia? is primordial tissue present?
Incomplete; yes
Endoderm - floor of primitive pharynx
Pataus; fetal alcohol syndrome
Mesoderm; nucleous pulposos
26. Pyloric stenosis is characterized by _____________ of muscularis externis in the sphincter
Mullerian inhibitory factor from Sertoli cells; increased androgen from Leydig cells
Rhombencephalon
hypertrophy
Common carotid and internal carotid
27. What are markers for neural tube defects in the amniotic cavity? CSF?
...
All or none
Increased AFP and acetycholinesterase (not ACh!) in CSF
Week 8
28. From What do the embryoblast and trophoblast form from? What does the embryoblast split into? the trophoblast?
Neuroectoderm
Blastocyst; epiblast and hypoblast; synctiotrophoblast and cytotrophoblast
Sperm plus egg
Amniotic cavity and yolk sac
29. The spleen is ____________ in origin and supplied by a foregut artery
Common carotid and internal carotid
Germinal matrix hemorrhage
mesodermal
1st
30. From What embryonic layer do the ependymal cells arise?
Arnold chiari; syringomyelia
Rhombencephalon
Neuroectoderm
Decidual basalis
31. Where is the mothers blood located in the placenta?
Week 8
Neuroectoderm
Lacunae in between the chorionic villi
Fetal and maternal
32. What is a zygote?
Neural crest migration - they then cause spiral
5th
Ventral bud
Sperm plus egg
33. What embryological structure gives rise to the coronary sinus?
Outgrowth of mesonephric as ureteric bud; most caudal
Ventral bud
is no longer intact
Left horn of the sinus venosus
34. From what does bicornuate uterus arise? What is it associated with?
Blastocyst; epiblast and hypoblast; synctiotrophoblast and cytotrophoblast
Incomplete fusion of paramesonephric ducts; UT abnormalities and infertility
Membrane - all 3 from 1st appartus
Failure of the urachus to obliterate
35. What causes the transposition of the great vessels? What does it result in?
Allantois
Failure to spiral (aorta coming out of RV and PA coming out of left ventricle)- two completely separate systems
Pataus; fetal alcohol syndrome
Branchial arch 2
36. What does the first branchial pouch create?
Epispadias
Ring of pancreatic tissue can cause duodenal narrowing; ventral pancreatic bud abnormally encircles 2nd part of duodenum
Initial left to right shunting - then switches
Endoderm lined structures of ear: middle ear cavity - eustacian tube - mastoid air cells
37. From What embryonic layer are the serous linings of the body cavities from? for ex - peritoneum?
Thyroglossal duct; persists as pyramidal lobe of thyroid; foramen cecum on tongue is normal remnant of thyroglossal duct
...
VACTERL; OCPs and maternal diabetes
4th pouch
38. Which branchial apparatus develops into the superior parathyroids?
Arnold Chiari and Dandy Walker; Arnold Chiari; Dandy Walker; Arnold Chiari
4th pouch
Ovarian ligament and round ligament of uterus; anchors testes within scrotum
3rd pouch
39. From what are the umbilical arteries and veins derived from?
Occiptal
Week 8
Allantois
Mesoderm; epiblast
40. From What embryonic layer do the salivary - sweat and mammary glands arise?
All or none
Surface ectoderm
Maxillary
Allantois
41. what results if they dont? What can increase the risks of this?
Ectoderm
Cerebral hemisphere - thalami
Persistent connection between amniotic cavity and spinal canal; low folic acid
Rhombencephalon
42. What does DHT turn the labioscrotal swelling into? estrogen?
Mesoderm
Ectoderm; endoderm
Midgut; 10th week
Scrotum; labia majora
43. What is the kidney that functions at the interim kidney in the 1st trimester? What does it later contribute to?
Mesoderm
Thalidomide; nausea
Mesonephros; male genital system
3rd pouch
44. From What embryonic layer is the bladder and urethra from?
primary palate
arnold chiari associated with thoraclumbar myelomeningocele
Neural crest development; MEN 2A (pheo - PTH tumor - parafollicular cell tumor)
Mesoderm
45. Where is the most common ectopic thyroid tissue?
LH
monoamniotic
Decreases
Tongue
46. When does the notochord form? and When does the neural plate form?
Oxygenated; placenta to fetus (IVC)
Tongue
Mesoderm; 3 week
Bones - cartilage - and nerves
47. What do the groove/clefts of the branchial apparatus correlate to?
Ectoderm
Blastocyst; epiblast and hypoblast; synctiotrophoblast and cytotrophoblast
Dorsal ventral axis
DES
48. Septum primum (patent foramen oval) caused by excessive resorption of...
No organ in each; agenesis no primordial tissue
septum primum and/or secundum
80%
Dorsal ventral axis
49. what muscles are derived from branchial arch 6? CN?
Deoxygenated blood; fetal internal iliac arteries to placenta
SRY gene on Y chromosomes; sertoli and leydi; MIF and androgens; suppression of paramesonephric ducts and dev. of mesonephric (all respectively)
All intrinsic muscles of larynx except cricothyroid; CN X (recurrent laryngeal nerve - speaking)
External auditory meatus
50. What artery is derived branchial (aortic) arch 4?
Ectoderm - mesoderm - endoderm; epiblast - primitive streak - hypoblast; week 3
Aortic arch and prox part of subclavian
Aortic arch (from left side); right subclavian (on the right)
Outgrowth of mesonephric as ureteric bud; most caudal