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USMLE Pathophys

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Ret
What oncogene is a/w MEN 2a/b
hemosiderinurea and thrombosis
propylthiouracil side effects
hemangioblastomas of retina/cerebellum/medulla

2. Chloroquine and primaquine
what meds treat malaria
MofA Levothyroxine
Lateral geniculate nucleus
GFAP positive

3. Cell type involved in most ovarian tumors
What oncogene is a/w MEN 2a/b
iduronidase sulfatase
epithelial
branching rods on oral infection

4. Medullary
brain tumor with psammona bodies
child with partial albinism - peripherial neuropathy - recurrent infections
most common arrthymia
cancer arising from parafollicular C cells

5. Tay Sachs
GM2 ganglioside accumulation
catalase negative
Bisphosphonates MofA
barbituates withdrawal

6. Criglar Najar
adenomyosis
brain tumor with perivascular pseudorosettes
currant jelly stool
absent UTPGT

7. Hurlers
placenta previa
hallmark sign of COPD
alpha L iduronidase
UMN signs

8. Meningioma
absent UTPGT
brain tumor with psammona bodies
oligodendrioglia
pigmented iris hamartomas - neural tumors

9. I- cell disease
deficiency of mannose phosphorylation
alpha 1 anti - trypsin
what meds treat malaria
P450 inducers

10. Antibody binds to gp2b/3a - preventing aggregation
P450 inducers
Abciximab
Lateral geniculate nucleus
crinkled paper cytoplasm

11. BCG PQRS
P450 inducers
antibiotic with SE of eosinophilia
cause of high pH vaginal discharge
Where does the dorsal column decussate?

12. Atrial fibrillation
optically clear nuclei (orphan annie)
cause of low pH vaginal discharge
cells destroyed in MS
most common arrthymia

13. Complete
hydatidiform mole with crazy high hCG
ventral posterior nucleus - medial part
rabies
solitarius nucleus

14. Cocain and sumatriptan
What causes coronary vasospasm as a SE?
H. flu
what nerve innervates the muscles of mastication?
defective tyrosine kinase

15. Membranous GN
precursor to GABA
spike and dome on microscope
Aschoff bodies
GM2 ganglioside accumulation

16. Neutrophil chemotactic agent 'neutrophils arrive B4 others'
supraoptic nucleus of hypothalamus
LTB4
lysosomal storage disease a/w renal disease
defective tyrosine kinase

17. Cowdry type A inclusions
brain tumor a/w von hipple - linadu syndrome
What oncogene is a/w MEN 2a/b
intranuclear inclusions seen in herpes simplex encephalitis
which nerve lifts the eyelid?

18. Gauchers
cough - conjunctivitis - coryza - fever
alpha galacosidase A
beta glucocerebrosidase
antibiotic with SE of eosinophilia

19. Microglia
form multinucleated giant cells in the CNS when infected with HIV
benzos antidote
probenecid
3 tumors of MEN 2b

20. Protamine sulfate
anti - platelet antibodies
What artery causes locked in syndrome
heparin antidote
mildly decreased UDPGT

21. Hemangioblastoma
barbituates withdrawal
brain tumor with foamy cells and high vascularity
what inhibits prolactin secretion
anti - mitochondrial antibodies

22. G1/S & G2/M
most common bacteria in GI tract
Shigella
what checkpoint is p53 involved with?
order of nerve blockade

23. Obstructive - COPD
grossly black liver
lysosomal storage disease a/w renal disease
infliximab
pt has extended expiratory phase

24. Oligodendroglia
What oncogene is a/w MEN 2a/b
spike and dome on microscope
kawasaki
looks like fried eggs under histologic staining

25. Primary hyperaldosteronism (HTN - hypokalemia - metabolic alkalosis)

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26. Von Hippel Lindau
hemangioblastomas of retina/cerebellum/medulla
absent UTPGT
chromosome 4
hep B seropositivity in 30% of patients

27. Oligodendoglia
cause of malignant hyperthermia
child with eczema - coarse facial features - cold abscesses
myelinates multiple CNS axons
antibody against philadelphia chromosome

28. Hurlers
What oncogene is a/w MEN 2a/b
locus ceruleus
corneal clouding & MR
cough - conjunctivitis - coryza - fever

29. Cause release of preformed insulin
best effect of triglycerides/VLDL
sulfonylureas
pt has extended expiratory phase
sclerosing adenosis

30. Fibrates
hemosiderinurea + thrombosis
best effect of triglycerides/VLDL
diphtheria treatment
What hormones share a common alpha subunit

31. TNF receptor
locus ceruleus
dose response curve with noncompetitive antagonist
etanercept
sturge weber syndrome

32. Panacinar
strawberry tongue
What artery causes locked in syndrome
locus ceruleus
alpha 1 anti - trypsin

33. Demeclycocycline or water restriction
whats the V/Q at the base of the lung
complete mole components
treatment for SIADH
silver stain of gram negative rods

34. Body sensation
catalase positive coagulase negative
ventral posterior nucleus - lateral part
follicular
most common bacteria in GI tract

35. Sulfonamides - hydralazine - isonazid - procainamide - phenytoin
drug induced lupus
Where does the lateral corticospinal decussate?
kluver bucy
Schiller Duval bodies

36. Norepinephrine
epithelial
grossly black liver
locus ceruleus
partial mole components

37. Decreases platelet aggregation - anti - pyretic and analgesic - high dose is anti - inflammatory
lisch nodules
Bisphosphonates MofA
fusion inhibitors
low dose ASA effects - intermediate dose - high dose

38. Bilateral renal agenesis or posterior urethral valves in males
oligohydramnios
blood supply for thalamus
placenta previa
failure of endodermal development

39. Function as bronchoconstrictors - vasoconstrictors - sm mm contraction and increased vascular permability
lead antidote
G cells
erythema nodosum
LT C4 D4 E4

40. Naloxone/naltrexone
Lewy bodies composition
most common testicular tumor
opioids antidote
hemosiderinurea and thrombosis

41. Hemolysis - elevated LFTs - Low Platelets
diphtheria treatment
mitral valve prolapse - liver diseae - berry aneurysm
rabies
HELLP syndrome

42. Posterior communicating - posterior cerebral - anterior choroidal arteries
fusion inhibitors
SE: elevated LFTS - myositis
What oncogene is a/w MEN 2a/b
blood supply for thalamus

43. Penicillamine
testicular tumor that can present with gynecomastia
copper - arsenic - gold antidote
benzos antidote
cells destroyed in MS

44. Mucocutaneous lymph node syndrome - necrotizing vasculitis - coronary aneurysms - strawberry tongue
may lead to multiple personalities
kawasaki
what meds treat malaria
What oncogene is a/w MEN 2a/b

45. A few levels above the level of entry
colchicine
locus ceruleus
Where does the spinothalamic decussate?
hydrocele

46. Chediak - Higashi
pt has extended expiratory phase
meissners
absent UTPGT
child with partial albinism - peripherial neuropathy - recurrent infections

47. Rhabdomyoma
bocks PRPP synthetase to block purine synthesis
most common primary cardiac tumor in kiddos
pigmented iris hamartomas - neural tumors
hydatidiform mole with crazy high hCG

48. Alpha synuclein
which nerve lifts the eyelid?
dose response curve change with competitive antagonist
chromosome 4
Lewy bodies composition

49. Increased acini and intralobular fibrosis
sclerosing adenosis
3 tumors of MEN 2b
adenomyosis
hallmark sign of COPD

50. Medulla
TZD (glitazones) MofA
Where does the dorsal column decussate?
anti - platelet antibodies
erythema nodosum