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USMLE Pathophys

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Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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1. Sulfonamides - hydralazine - isonazid - procainamide - phenytoin
drug induced lupus
adenomyosis
locus ceruleus
Shigella

2. Gonorrhea
Abciximab
thayer martin media
paraventricular nucleus of hypothalamus
drug induced lupus

3. 2 sperm + empty egg (no fetal parts)
cause of increased myometrial excitability
dose response curve change with competitive antagonist
complete mole components
GFAP positive

4. Medulla
schwann cells
best effect on HDL
FGFR3 mutation
Where does the dorsal column decussate?

5. Leydig cell tumor
deficiency of mannose phosphorylation
testicular tumor that can present with gynecomastia
11 beta hydroxylase deficiency
Where does the dorsal column decussate?

6. Gilberts
most common testicular tumor in infants and children up to 3 years of age
shown to slow progression of diabetic neuropathy
mildly decreased UDPGT
first line for absence seizures

7. Subacute (De Quervain's) thyroiditis
beta glucocerebrosidase
3 tumors of MEN 1
What thyroid pathology has an extremely tender thyroid gland
hippocampus

8. Bromocriptine
copper - arsenic - gold antidote
sulfonylureas
anti - epithelial antibodies
what inhibits prolactin secretion

9. Lymphoma

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10. Centriacinar
von Hippel Lindau disease
smoking emphysema
opioid withdrawal
3 tumors of MEN 2a

11. Deficiency of aldosterone and cortisol

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12. Trichomonas or bacterial vaginosis
thayer martin media
FGFR3 mutation
cause of high pH vaginal discharge
first line for cardiogenic shock

13. Anxiety - seizures - delirium - life threatening CV collapse
What oncogene is a/w MEN 2a/b
LMN signs
barbituates withdrawal
sumatriptan

14. NE
Galactocerebrosidase deficiency
most common first line agent for septic shock
smoking emphysema
pseudopalisading necrosis

15. Suspensory ligament of ovaries
what meds treat malaria
contains ovarian vessels
most common testicular tumor in infants and children up to 3 years of age
blood supply for thalamus

16. Hypoglycemia
defective tyrosine kinase
hallmark sign of COPD
brain tumor with perivascular pseudorosettes
sulfonylureas side effect

17. Atrial fibrillation
meissners
lysosomal storage disease - demyelinating disease
most common arrthymia
drug that blocks purine synthesis and is metabolized by xanthine oxidase

18. Chronic gout. inhibits reabsorbtion of uric acid in PCT
ependymal cells
probenecid
intranuclear inclusions seen in herpes simplex encephalitis
papillary thyroid cancer

19. Ethosuximide
lysosomal storage disease - demyelinating disease
first line for absence seizures
solitarius nucleus
supraoptic nucleus of hypothalamus

20. Hairless skin - dynamic fine touch
I cells
meissners
anti - epithelial antibodies
hemosiderinurea + thrombosis

21. Intrinsic factor
melanoma tumor marker
parietal cells
subluxation of lens
VA/VL

22. Posterior communicating - posterior cerebral - anterior choroidal arteries
TZD (glitazones) MofA
astrocytes
barbituates withdrawal
blood supply for thalamus

23. Polyarteritis nodosa
brain tumor with perivascular pseudorosettes
most common lysosomal storage disease
hep B seropositivity in 30% of patients
HELLP syndrome

24. SICK PEG
heparin antidote
sarcoma botyroides
P450 Inhibitors
most common bacteria in GI tract

25. CCK
blood supply for thalamus
sumatriptan
3 tumors of MEN 2a
I cells

26. Cavernous hemangiomas in skin - mucosa & organs; autosomal dominant - a/w renal CA - hemangioblastoma in retina - brainstem & cerebellum
blocks ADP receptors to inhibit platelet aggregation
von Hippel Lindau disease
iduronidase sulfatase
ventral posterior nucleus - medial part

27. Membranoproliferative GN
brain tumor with psammona bodies
tram - track on microscope
smoking emphysema
branching rods on oral infection

28. Serotonin
21 hydroxylase deficiency
raphe nucleus
placenta previa
x- linked recessive lysosomal storage diseases

29. Gauchers
I cells
dose response curve with noncompetitive antagonist
Aschoff bodies
most common lysosomal storage disease

30. Medulloblastoma
heXosaminidase
What anti - hypertensive drug has the side effect of first dose orthostatic hypotension
homer wright rosettes
G cells

31. Naloxone/naltrexone
polyhydramnios
catalase negative
opioids antidote
ependymal cells

32. Seborric keratosis
sturge weber syndrome
mitral valve prolapse - liver diseae - berry aneurysm
keratin filled cysts
infliximab

33. Inhibitory in the SC
glycine
iduronidase sulfatase
thromboxane A2
What causes coronary vasospasm as a SE?

34. Damaged in multiple sclerosis
most common protozoal infection in US
what nerve innervates the muscles of mastication?
follicular
oligodendrioglia

35. Criglar Najar
S cells
What oncogene is a/w MEN 2a/b
absent UTPGT
VA/VL

36. Mucocutaneous lymph node syndrome - necrotizing vasculitis - coronary aneurysms - strawberry tongue
P450 Inhibitors
inheritance pattern for all MENs
von Hippel Lindau disease
kawasaki

37. Bruton's agammaglobulinemia
macrolides use (PUS)
beta glucocerebrosidase
cancer arising from parafollicular C cells
defective tyrosine kinase

38. Dobutamine
polyhydramnios
Shigella
first line for cardiogenic shock
thromboxane A2

39. Oculomotor
strawberry tongue
what meds treat malaria
epithelial
which nerve lifts the eyelid?

40. Seminoma
erythema nodosum
3 tumors of MEN 2b
corneal clouding & MR
most common testicular tumor

41. Hemangioblastoma
child with eczema - coarse facial features - cold abscesses
BCG PQRS
Galactocerebrosidase deficiency
brain tumor a/w von hipple - linadu syndrome

42. Body sensation
papillary thyroid cancer
ventral posterior nucleus - lateral part
tram - track on microscope
brain tumor with fried egg appearance

43. Basal cell carcinoma
antibody against philadelphia chromosome
palisading nuclei - locally invasive
complete mole components
locus ceruleus

44. Hemangioblastoma
brain tumor with foamy cells and high vascularity
MofA of N- aceylcysteine
sumatriptan
ovarian tumor with elevate hCG

45. Hunters
palisading nuclei - locally invasive
papillary thyroid cancer
contains ovarian vessels
iduronidase sulfatase

46. Ret
thayer martin media
eczema/recurrent infections/thrombocytopenia
most common breast tumor in women under 25
What oncogene is a/w MEN 2a/b

47. Negri bodies
rabies
G cells
ambiguous nucleus
Addison's

48. A few levels above the level of entry
Where does the spinothalamic decussate?
P450 Inhibitors
basal nucleus of Meynert
GABA - glutamine

49. Streptococcus
catalase positive coagulase negative
Lateral geniculate nucleus
complete mole components
catalase negative

50. Prevents incorporation into host DNA
nucleoside reverse transcriptase inhibitors
most common bacteria in GI tract
lewy body composition
tram - track on microscope

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USMLE Pathophys

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