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USMLE Pathophys

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Lactic acidosis
P450 Inhibitors
oligohydramnios
sturge weber syndrome
metformin side effect

2. ITP
anti - platelet antibodies
catalase positive coagulase negative
chromosome 4
enzyme used to conjugate bilirubin

3. Papillary CA of thyroid
psammoma bodies
Bisphosphonates MofA
optically clear nuclei (orphan annie)
TZD (glitazones) MofA

4. Fabrys
cause of increased myometrial excitability
most common protozoal infection in US
iduronidase sulfatase
alpha galacosidase A

5. Basilar
HELLP syndrome
infliximab
abruptio placentae
What artery causes locked in syndrome

6. Papillary
D cells
hydatidiform mole with crazy high hCG
thyroid cancer associtated with RET oncogene
optically clear nuclei (orphan annie)

7. Huntingtons chorea
granulosa cell tumor secretes what?
beta glucocerebrosidase
chromosome 4
GABA - glutamine

8. Masculinization - hypovolemic shock
ovarian tumor with psammoma bodies
chief cells
21 hydroxylase deficiency
alpha 1 anti - trypsin

9. Ach
nucleoside reverse transcriptase inhibitors
basal nucleus of Meynert
may lead to multiple personalities
erythema nodosum

10. Gauchers
ovarian tumor with psammoma bodies
VA/VL
beta glucocerebrosidase
SE: elevated LFTS - myositis

11. Achondroplasia
best effect of triglycerides/VLDL
most common breast mass in pre - menopausal women
FGFR3 mutation
myelinates on PNS

12. Babinski - weakness - increased reflexes & tone - spastic paralysis
optically clear nuclei (orphan annie)
ovarian tumor that resembles bladder epithelium
lead antidote
UMN signs

13. Antibody binds to gp2b/3a - preventing aggregation
adenomyosis
placenta previa
Abciximab
most common breast mass in pre - menopausal women

14. Medullary thyroid - pheochromocytoma - oral/intestinal ganglionueromatosis
rabies
3 tumors of MEN 2b
Where does the dorsal column decussate?
Shigella

15. Auditory (Medial for Music)
thymidylate synthase
medial geniculate nucleus
dorsal motor nucleus
child with partial albinism - peripherial neuropathy - recurrent infections

16. Neurofibromatosis
lisch nodules
3 tumors of MEN 2a
mitral valve prolapse - liver diseae - berry aneurysm
blood supply for thalamus

17. 2 sperm + 1 egg (fetal parts present)
branching rods on oral infection
antibody against philadelphia chromosome
cause of low pH vaginal discharge
partial mole components

18. Atrial fibrillation
anti - platelet antibodies
intranuclear inclusions seen in herpes simplex encephalitis
most common arrthymia
ovarian tumor with psammoma bodies

19. Seminoma
most common testicular tumor
cause of malignant hyperthermia
oligodendrioglia
precursor to GABA

20. Inner lining of ventricles - make CSF - originate from neuroectoderm
ependymal cells
enzyme used to conjugate bilirubin
thyroid cancer associtated with RET oncogene
dorsal motor nucleus

21. Choriocarcinoma
tumor composed of cytotrophoblasts and syncytiotrophoblasts
beta glucocerebrosidase
most common testicular tumor in infants and children up to 3 years of age
opioid withdrawal

22. Macrolides
most common first line agent for septic shock
opioids antidote
sulfonylureas MofA
antibiotic with SE of eosinophilia

23. HTN - proteinuria - edema
locus ceruleus
erythema nodosum
preeclampsia
papillary thyroid cancer

24. Pemphigus vulgaris
tumor with call - exner bodies
anti - epithelial antibodies
bocks PRPP synthetase to block purine synthesis
shown to slow progression of diabetic neuropathy

25. Ach
heXosaminidase
basal nucleus of Meynert
cells destroyed in Guillain Barre
opioid withdrawal

26. Schwann cells
precursor to GABA
myelinates on PNS
treatment for SIADH
vasculitis of infants and children - involving coronary arteries

27. Autosomal dominant
SE: facial flushing
catalase negative
inheritance pattern for all MENs
Schiller Duval bodies

28. ADPKD
mitral valve prolapse - liver diseae - berry aneurysm
most common testicular tumor in infants and children up to 3 years of age
oligohydramnios
whats the V/Q at the apex of the lung

29. Decreases platelet aggregation - anti - pyretic and analgesic - high dose is anti - inflammatory
kluver bucy
LT C4 D4 E4
Abciximab
low dose ASA effects - intermediate dose - high dose

30. Homocystienuria - Marfans
Schiller Duval bodies
subluxation of lens
increased MCHC and hemolytic anemia
ovarian tumor that resembles bladder epithelium

31. Actinomyces
branching rods on oral infection
lewy body composition
5 alpha reductase deficiency
treatment for SIADH

32. Port wine stains - ipsilateral leptomeningeal angioma; can cause glaucoma - seizures - hemipareis - and MR
treatment for SIADH
sturge weber syndrome
subluxation of lens
mildly decreased UDPGT

33. Estrogen
honey crusted lesions common around nose/lips
cause of LH surge
most common bacteria in GI tract
cause of increased myometrial excitability

34. Medulla
thayer martin media
Where does the dorsal column decussate?
lisch nodules
most common first line agent for septic shock

35. Antitoxin - penicillin - DPT vaccine
H. flu
heXosaminidase
diphtheria treatment
corneal clouding & MR

36. Sulfonamides - Isonizid - Cimetidine - Ketoconazole - Erythromyicn - grapefruit juice - protease inhibitors
SICK PEG
What are the hormone changes seen in menopause
3 tumors of MEN 2a
form multinucleated giant cells in the CNS when infected with HIV

37. Radial nerve - deep brachial artery
ovarian tumor with elevate hCG
midshaft break of humerus
cause of increased myometrial excitability
GABA - glutamine

38. Makes ADH
leydig cell tumor
What oncogene is a/w MEN 2a/b
ambiguous nucleus
supraoptic nucleus of hypothalamus

39. Anxiety - seizures - delirium - life threatening CV collapse
Schiller Duval bodies
Shigella
barbituates withdrawal
brenner tumor

40. Trigeminal
tumor with call - exner bodies
what nerve innervates the muscles of mastication?
placenta previa
most common protozoal infection in US

41. Hemangioblastoma
brain tumor a/w von hipple - linadu syndrome
paraventricular nucleus of hypothalamus
most common breast tumor in women under 25
eczema/recurrent infections/thrombocytopenia

42. TSH - LH - FSH - hCG
enzyme used to conjugate bilirubin
3 tumors of MEN 2b
What hormones share a common alpha subunit
chromosome 4

43. A/w esophageal/duodenal atresia and anencephaly
polyhydramnios
cough - conjunctivitis - coryza - fever
beta glucocerebrosidase
supraoptic nucleus of hypothalamus

44. TNF receptor
etanercept
most common arrthymia
currant jelly stool
GABA - glutamine

45. Pepsin
cells destroyed in Guillain Barre
tumor with call - exner bodies
Aschoff bodies
chief cells

46. 0.6
smoking emphysema
Shigella
whats the V/Q at the base of the lung
ovarian tumor that resembles bladder epithelium

47. Measles
cause of low pH vaginal discharge
cough - conjunctivitis - coryza - fever
21 hydroxylase deficiency
branching rods on oral infection

48. PNH
ovarian tumor with elevate hCG
LT C4 D4 E4
hemosiderinurea + thrombosis
corneal clouding & MR

49. Krabbe's
Galactocerebrosidase deficiency
What anti - hypertensive drug has the side effect of first dose orthostatic hypotension
diphtheria treatment
dose response curve change with competitive antagonist

50. Flumazenil
barbituates withdrawal
benzos antidote
subluxation of lens
most common testicular tumor