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USMLE Pathophys

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Prevents incorporation into host DNA
hydatidiform mole with crazy high hCG
nucleoside reverse transcriptase inhibitors
papillary thyroid cancer
erythema nodosum

2. Motor
medial geniculate nucleus
GABA - glutamine
VA/VL
master clock for circadian rhythms

3. H. Influenza
gram + bacteria that requires NAD and hemin for growth
most common arrthymia
lisch nodules
etanercept

4. Rheumatic fever
oligohydramnios
tumor composed of cytotrophoblasts and syncytiotrophoblasts
oligodendrioglia
Aschoff bodies

5. Glutamate
brain tumor with psammona bodies
hemangioblastomas of retina/cerebellum/medulla
form multinucleated giant cells in the CNS when infected with HIV
precursor to GABA

6. Inner lining of ventricles - make CSF - originate from neuroectoderm
optically clear nuclei (orphan annie)
meissners
ependymal cells
copper - arsenic - gold antidote

7. 2 sperm + 1 egg (fetal parts present)
barbituates withdrawal
sturge weber syndrome
cancer associated with Hashimoto's thyroiditis
partial mole components

8. Suspensory ligament of ovaries
contains ovarian vessels
first line for absence seizures
lisch nodules
plenta accreta

9. Ependymoma
branching rods on oral infection
brain tumor with perivascular pseudorosettes
sulfonylureas
17 alpha hydroxylase deficiency

10. Yolk sac tumor
melanoma tumor marker
Schiller Duval bodies
most common lysosomal storage disease
sphingomyelinase deficiency

11. Gilberts
mildly decreased UDPGT
Shigella
strawberry tongue
tumor with call - exner bodies

12. Anxiety - seizures - delirium - life threatening CV collapse
barbituates withdrawal
ovarian tumor with elevate hCG
iduronidase sulfatase
most common testicular tumor

13. Criglar Najar
S cells
whats the V/Q at the apex of the lung
absent UTPGT
thymidylate synthase

14. Metachromatic leukodystrophy
complete mole components
macrolides use (PUS)
most common primary cardiac tumor in kiddos
lysosomal storage disease - demyelinating disease

15. Deficiency of aldosterone and cortisol

16. Pepsin
chief cells
17 alpha hydroxylase deficiency
ambiguous nucleus
vasculitis of infants and children - involving coronary arteries

17. Astrocytoma & glioblastoma multiforme
GFAP positive
medial geniculate nucleus
testicular tumor that can present with gynecomastia
found in hairless skin

18. Seminoma
most common testicular tumor
solitarius nucleus
What causes coronary vasospasm as a SE?
adenomyosis

19. Intussception
kawasaki
GFAP positive
currant jelly stool
enzyme used to conjugate bilirubin

20. Bromocriptine
raphe nucleus
absent UTPGT
what inhibits prolactin secretion
alpha 1 anti - trypsin

21. A few levels above the level of entry
child with eczema - coarse facial features - cold abscesses
Where does the spinothalamic decussate?
preeclampsia
antibiotic with SE of eosinophilia

22. Seborric keratosis
ependymal cells
keratin filled cysts
21 hydroxylase deficiency
What oncogene is a/w MEN 2a/b

23. Impetigo
honey crusted lesions common around nose/lips
hydrocele
dermatin sulfate accumulation
cause of high pH vaginal discharge

24. Dubin Johnson
grossly black liver
P450 inducers
LTB4
cause of increased myometrial excitability

25. CCK
I cells
found in hairless skin
grossly black liver
thromboxane A2

26. Decreases platelet aggregation - anti - pyretic and analgesic - high dose is anti - inflammatory
resembles an onion in cross section
optically clear nuclei (orphan annie)
low dose ASA effects - intermediate dose - high dose
schwann cells

27. Niacins
Lateral geniculate nucleus
best effect on HDL
which nerve lifts the eyelid?
LT C4 D4 E4

28. Neutrophil chemotactic agent 'neutrophils arrive B4 others'
homer wright rosettes
supraoptic nucleus of hypothalamus
LTB4
cause of high pH vaginal discharge

29. 0.6
ovarian tumor with psammoma bodies
complete mole components
whats the V/Q at the base of the lung
thromboxane A2

30. Membranoproliferative GN
inheritance pattern for all MENs
hallmark sign of COPD
complete mole components
tram - track on microscope

31. TNF receptor
S cells
opioids antidote
low dose ASA effects - intermediate dose - high dose
etanercept

32. Pacinian
resembles an onion in cross section
catalase positive coagulase negative
myelinates multiple CNS axons
locus ceruleus

33. Pemphigus vulgaris
low dose ASA effects - intermediate dose - high dose
anti - epithelial antibodies
mildly decreased UDPGT
dermatin sulfate accumulation

34. Medullary thyroid - pheochromocytoma - oral/intestinal ganglionueromatosis
3 tumors of MEN 2b
SE: facial flushing
Shigella
thymidylate synthase

35. Motor innervation of pharynx - larynx and upper esophagus
ambiguous nucleus
von Hippel Lindau disease
PGI2 (prostacyclin))
hydatidiform mole with crazy high hCG

36. Oligosaccaride hydrolase
kluver bucy
5 alpha reductase deficiency
rate limiting step in carb digestion
ovarian tumor that resembles bladder epithelium

37. Estrogen
oligodendrioglia
basal nucleus of Meynert
cause of increased myometrial excitability
most common breast tumor in women under 25

38. Lymphoma

39. Amygdala
shown to slow progression of diabetic neuropathy
kluver bucy
solitarius nucleus
pt has extended expiratory phase

40. Penicillamine
hemangioblastomas of retina/cerebellum/medulla
enzyme used to conjugate bilirubin
copper - arsenic - gold antidote
SE: torsades de pointes

41. Lactic acidosis
metformin side effect
what nerve innervates the muscles of mastication?
increased MCHC and hemolytic anemia
branching rods on oral infection

42. Prazosin
What anti - hypertensive drug has the side effect of first dose orthostatic hypotension
catalase positive coagulase negative
most common first line agent for septic shock
first line for absence seizures

43. Dobutamine
first line for cardiogenic shock
SICK PEG
Lewy bodies composition
lisch nodules

44. Von Hippel Lindau
nucleoside reverse transcriptase inhibitors
order of nerve blockade
hemangioblastomas of retina/cerebellum/medulla
most common gyno malignancy

45. Papillary
midshaft break of humerus
thyroid cancer associtated with RET oncogene
etanercept
form multinucleated giant cells in the CNS when infected with HIV

46. Actinomyces
supraoptic nucleus of hypothalamus
branching rods on oral infection
basal nucleus of Meynert
infliximab

47. Schwann cells
smoking emphysema
grossly black liver
anti - platelet antibodies
cells destroyed in Guillain Barre

48. Cavernous hemangiomas in skin - mucosa & organs; autosomal dominant - a/w renal CA - hemangioblastoma in retina - brainstem & cerebellum
brain tumor with fried egg appearance
what cells secrete somatostatin
locus ceruleus
von Hippel Lindau disease

49. Invasive ductal
GFAP positive
placenta previa
strawberry tongue
most common breast cancer

50. Trichomonas - Giardia
most common protozoal infection in US
MofA of N- aceylcysteine
blood supply for thalamus
astrocytes