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USMLE Pathophys

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Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Oligosaccaride hydrolase
cause of LH surge
rate limiting step in carb digestion
deficiency of mannose phosphorylation
ovarian tumor with elevate hCG

2. Ovarian bengin tumor...looks like bladder
barbituates withdrawal
LTB4
brenner tumor
found in hairless skin

3. Streptococcus
preeclampsia
brain tumor with perivascular pseudorosettes
catalase negative
blood supply for thalamus

4. 2 sperm + empty egg (no fetal parts)
complete mole components
ovarian tumor with psammoma bodies
MofA of N- aceylcysteine
sarcoma botyroides

5. Invasive ductal CA
most common breast mass in postmenopausal women
21 hydroxylase deficiency
increased MCHC and hemolytic anemia
supraoptic nucleus of hypothalamus

6. NE
hallmark sign of COPD
most common first line agent for septic shock
S cells
cause of high pH vaginal discharge

7. Cells of BBB
thayer martin media
cells destroyed in Guillain Barre
astrocytes
homer wright rosettes

8. Trigeminal
thyroid cancer associtated with RET oncogene
what nerve innervates the muscles of mastication?
Aschoff bodies
etanercept

9. Inner lining of ventricles - make CSF - originate from neuroectoderm
BCG PQRS
ependymal cells
lysosomal storage disease - demyelinating disease
macrolides use (PUS)

10. Schwann cells
myelinates on PNS
kluver bucy
shown to slow progression of diabetic neuropathy
failure of endodermal development

11. Pneumonia - URIs - STDS
most common bacteria in GI tract
catalase negative
most common lysosomal storage disease
macrolides use (PUS)

12. Causes vasoconstriction (use for acute migraines)
sphingomyelinase deficiency
most common testicular tumor in infants and children up to 3 years of age
ovarian tumor with elevate hCG
sumatriptan

13. Decreased follicles & estrogen with increased FSH & LH
What are the hormone changes seen in menopause
shown to slow progression of diabetic neuropathy
rabies
astrocytes

14. Schwann cells
What are the hormone changes seen in menopause
LMN signs
cells destroyed in Guillain Barre
sulfonylureas side effect

15. Fabrys
bocks PRPP synthetase to block purine synthesis
cause of malignant hyperthermia
alpha galacosidase A
best effect on HDL

16. Makes ADH
supraoptic nucleus of hypothalamus
paraventricular nucleus of hypothalamus
cause of increased myometrial excitability
most common testicular tumor in infants and children up to 3 years of age

17. Wiscott - Aldrich
eczema/recurrent infections/thrombocytopenia
Lateral geniculate nucleus
Aschoff bodies
treatment for SIADH

18. Placenta attached to myometrium
P450 Inhibitors
tram - track on microscope
partial mole components
plenta accreta

19. Small diameter > large diameter; myelinated > unmyelinated
treatment of malignant hyperthermia
branching rods on oral infection
order of nerve blockade
preeclampsia

20. Gonorrhea
cause of increased myometrial excitability
heparin antidote
thayer martin media
hep B seropositivity in 30% of patients

21. Ret
What oncogene is a/w MEN 2a/b
most common primary cardiac tumor in kiddos
hydrocele
vasculitis a/w Hep B

22. Invasive ductal
nucleoside reverse transcriptase inhibitors
most common breast cancer
blocks ADP receptors to inhibit platelet aggregation
lewy body composition

23. Primary biliary cirrhosis
meissners
21 hydroxylase deficiency
branching rods on oral infection
anti - mitochondrial antibodies

24. Ethosuximide
Bisphosphonates MofA
first line for absence seizures
low dose ASA effects - intermediate dose - high dose
honey crusted lesions common around nose/lips

25. PPAR- gamma receptor agonist - which causes improved target cell response to insulin
TZD (glitazones) MofA
UMN signs
What anti - hypertensive drug has the side effect of first dose orthostatic hypotension
branching rods on oral infection

26. Granulosa cell tumor
SICK PEG
parietal cells
tumor with call - exner bodies
locus ceruleus

27. D cells of pancreas and gut
treatment for SIADH
sulfonylureas
cells destroyed in MS
what cells secrete somatostatin

28. Pemphigus vulgaris
anti - epithelial antibodies
myelinates multiple CNS axons
microglia
3 tumors of MEN 1

29. Radial nerve - deep brachial artery
cancer associated with Hashimoto's thyroiditis
hallmark sign of COPD
strawberry tongue
midshaft break of humerus

30. Hereditary spherocytosis
partial mole components
hydatidiform mole with crazy high hCG
I cells
increased MCHC and hemolytic anemia

31. Hurlers
deficiency of mannose phosphorylation
corneal clouding & MR
whats the V/Q at the base of the lung
What thyroid pathology has an extremely tender thyroid gland

32. Cant convert testosterone to DHT - ambiguous genitalia until puberty then penis at 12
cause of low pH vaginal discharge
5 alpha reductase deficiency
oligohydramnios
cancer arising from parafollicular C cells

33. Fibrates/statins
heXosaminidase
What causes coronary vasospasm as a SE?
SE: elevated LFTS - myositis
cough - conjunctivitis - coryza - fever

34. Fibroadenoma
most common breast tumor in women under 25
whats the V/Q at the apex of the lung
increased MCHC and hemolytic anemia
floppy mitral valve dissecting aortic aneurysm - berry aneurysm

35. TNF receptor
corneal clouding & MR
inheritance pattern for all MENs
etanercept
resembles an onion in cross section

36. Fabry's
myelinates on PNS
beta glucocerebrosidase
x- linked recessive lysosomal storage diseases
lysosomal storage disease a/w renal disease

37. Increases platelet aggregation and vasoconstriction
I cells
thromboxane A2
metformin side effect
homer wright rosettes

38. Attachment of placenta to lower uterine segment
hemosiderinurea + thrombosis
thromboxane A2
placenta previa
cells destroyed in MS

39. Hurlers
Bisphosphonates MofA
chromosome 4
what meds treat malaria
alpha L iduronidase

40. 0.6
myelinates multiple CNS axons
whats the V/Q at the base of the lung
21 hydroxylase deficiency
Aschoff bodies

41. Criglar Najar
What thyroid pathology has an extremely tender thyroid gland
absent UTPGT
alpha 1 anti - trypsin
dermatin sulfate accumulation

42. Aplastic anemia - rash - agranulocytosis
MofA of N- aceylcysteine
most common first line agent for septic shock
vasculitis of infants and children - involving coronary arteries
propylthiouracil side effects

43. Chloroquine and primaquine
infliximab
what meds treat malaria
psammoma bodies
benzos antidote

44. 6- mecaptopurine (metabolized by xanthine oxidase)
Galactocerebrosidase deficiency
bocks PRPP synthetase to block purine synthesis
heXosaminidase
SE: facial flushing

45. Bromocriptine
what checkpoint is p53 involved with?
what inhibits prolactin secretion
lisch nodules
Addison's

46. Meissner
LMN signs
PGI2 (prostacyclin))
most common lysosomal storage disease
found in hairless skin

47. Medulla
H. flu
Shigella
Where does the dorsal column decussate?
increased MCHC and hemolytic anemia

48. H. Influenza
5 alpha reductase deficiency
sarcoma botyroides
gram + bacteria that requires NAD and hemin for growth
vasculitis a/w Hep B

49. A few levels above the level of entry
Where does the spinothalamic decussate?
erythema nodosum
anti - epithelial antibodies
kawasaki

50. Rhabdomyoma
failure of endodermal development
most common primary cardiac tumor in kiddos
microglia
basal nucleus of Meynert

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USMLE Pathophys

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