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USMLE Pathophys

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Most common type of thyroid cancer
papillary thyroid cancer
MofA Levothyroxine
order of nerve blockade
Bisphosphonates MofA

2. Posterior communicating - posterior cerebral - anterior choroidal arteries
order of nerve blockade
Galactocerebrosidase deficiency
vasculitis a/w Hep B
blood supply for thalamus

3. Imabtinib
midshaft break of humerus
hep B seropositivity in 30% of patients
antibody against philadelphia chromosome
glycine

4. Protamine sulfate
heparin antidote
ventral posterior nucleus - lateral part
protease inhibitors MofA
cancer arising from parafollicular C cells

5. Suspensory ligament of ovaries
contains ovarian vessels
vasculitis of infants and children - involving coronary arteries
cells destroyed in MS
chief cells

6. Attachment of placenta to lower uterine segment
hallmark sign of COPD
oligodendrioglia
blood supply for thalamus
placenta previa

7. Atrial fibrillation
granulosa cell tumor secretes what?
most common arrthymia
most common primary cardiac tumor in kiddos
cells destroyed in Guillain Barre

8. Visual (Lateral for Light)
anti - platelet antibodies
Lateral geniculate nucleus
brain tumor with perivascular pseudorosettes
tumor with call - exner bodies

9. Gilberts
GABA - glutamine
granulosa cell tumor secretes what?
MofA of N- aceylcysteine
mildly decreased UDPGT

10. Bind viral gp41 subunit
fusion inhibitors
most common testicular tumor in infants and children up to 3 years of age
first line for absence seizures
oligodendrioglia

11. Dobutamine
beta glucocerebrosidase
most common breast cancer
first line for cardiogenic shock
catalase negative

12. Dissociative
mildly decreased UDPGT
may lead to multiple personalities
most common lysosomal storage disease
Shigella

13. Niacin
etanercept
anti - platelet antibodies
P450 inducers
SE: facial flushing

14. Trichomonas or bacterial vaginosis
leydig cell tumor
Conn's syndrome
infliximab
cause of high pH vaginal discharge

15. Motor innervation of pharynx - larynx and upper esophagus
ambiguous nucleus
keratin filled cysts
rabies
brain tumor with perivascular pseudorosettes

16. Gauchers
heXosaminidase
psammoma bodies
epithelial
beta glucocerebrosidase

17. Lactic acidosis
floppy mitral valve dissecting aortic aneurysm - berry aneurysm
brenner tumor
11 beta hydroxylase deficiency
metformin side effect

18. Anti - TNF antibody - use for RA but watch out for latent TB!
sulfonylureas side effect
infliximab
contains ovarian vessels
drug that blocks purine synthesis and is metabolized by xanthine oxidase

19. Chocolate agar
resembles an onion in cross section
sphingomyelinase deficiency
anti - mitochondrial antibodies
H. flu

20. Actinomyces
schwann cells
ovarian tumor with elevate hCG
branching rods on oral infection
x- linked recessive lysosomal storage diseases

21. Basilar
lysosomal storage disease a/w renal disease
What artery causes locked in syndrome
first line for absence seizures
medial geniculate nucleus

22. Causes vasoconstriction (use for acute migraines)
grossly black liver
sumatriptan
cause of LH surge
fusion inhibitors

23. Combo of inhaled anesthetics & succinylcholine
basal nucleus of Meynert
cause of malignant hyperthermia
pseudopalisading necrosis
SE: elevated LFTS - myositis

24. Inhibitory in the brain - stimulatory in the brain
GABA - glutamine
supraoptic nucleus of hypothalamus
dermatin sulfate accumulation
most common first line agent for septic shock

25. Inhibits viral assembly
Abciximab
protease inhibitors MofA
leydig cell tumor
failure of endodermal development

26. Rheumatic fever
mitral valve prolapse - liver diseae - berry aneurysm
t - PA - streptokinase antidote
Aschoff bodies
locus ceruleus

27. Hereditary spherocytosis
Where does the spinothalamic decussate?
Conn's syndrome
increased MCHC and hemolytic anemia
PTU

28. Estrogen
treatment for SIADH
hemangioblastomas of retina/cerebellum/medulla
thymidylate synthase
cause of increased myometrial excitability

29. Job's or LAD
neutrophils fail to respond to chemotaxic stimuli
meissners
pacinian
catalase negative

30. Medulla
placenta previa
Where does the lateral corticospinal decussate?
brain tumor with fried egg appearance
eczema/recurrent infections/thrombocytopenia

31. Glucuronyl transferase
glycine
best effect on HDL
enzyme used to conjugate bilirubin
lysosomal storage disease - demyelinating disease

32. Mucocutaneous lymph node syndrome - necrotizing vasculitis - coronary aneurysms - strawberry tongue
sarcoma botyroides
kawasaki
dorsal motor nucleus
hemosiderinurea + thrombosis

33. Ach
first line for absence seizures
spike and dome on microscope
basal nucleus of Meynert
drug induced lupus

34. Oligodendroglia
MPTP exposure causes depletion of what NT?
looks like fried eggs under histologic staining
locus ceruleus
grossly black liver

35. Tay SaX
Yolk sac tumor produces...
heXosaminidase
cause of high pH vaginal discharge
which nerve lifts the eyelid?

36. Hemangioblastoma
PGI2 (prostacyclin))
brain tumor a/w von hipple - linadu syndrome
most common testicular tumor
barbituates withdrawal

37. Choriocarcinoma
smoking emphysema
tumor composed of cytotrophoblasts and syncytiotrophoblasts
psammoma bodies
most common protozoal infection in US

38. Aminocaproic acid
D cells
t - PA - streptokinase antidote
resembles an onion in cross section
grossly black liver

39. ADPKD
most common first line agent for septic shock
sclerosing adenosis
sulfonylureas
mitral valve prolapse - liver diseae - berry aneurysm

40. Decreased efficacy - decreased Vmax
subluxation of lens
antibody against philadelphia chromosome
dose response curve with noncompetitive antagonist
follicular

41. Damaged in multiple sclerosis
oligodendrioglia
UMN signs
shown to slow progression of diabetic neuropathy
ambiguous nucleus

42. Subacute (De Quervain's) thyroiditis
intranuclear inclusions seen in herpes simplex encephalitis
microglia
What thyroid pathology has an extremely tender thyroid gland
ovarian tumor with elevate hCG

43. SICK PEG
whats the V/Q at the base of the lung
cause of low pH vaginal discharge
P450 Inhibitors
hep B seropositivity in 30% of patients

44. Astrocytoma & glioblastoma multiforme
sulfonylureas MofA
fusion inhibitors
GFAP positive
G cells

45. Centriacinar
most common protozoal infection in US
cancer associated with Hashimoto's thyroiditis
Bisphosphonates MofA
smoking emphysema

46. Estrogen
mitral valve prolapse - liver diseae - berry aneurysm
failure of endodermal development
cause of LH surge
kawasaki

47. Metachromatic leukodystrophy
UMN signs
what cells secrete somatostatin
ependymal cells
lysosomal storage disease - demyelinating disease

48. Anxiety - seizures - delirium - life threatening CV collapse
LMN signs
barbituates withdrawal
raphe nucleus
basal nucleus of Meynert

49. Increases platelet aggregation and vasoconstriction
lysosomal storage disease a/w renal disease
thromboxane A2
chief cells
leydig cell tumor

50. Gastrin
G cells
infliximab
sumatriptan
solitarius nucleus