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USMLE Pathophys

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Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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1. TSH - LH - FSH - hCG
ovarian tumor with elevate hCG
whats the V/Q at the base of the lung
SE: torsades de pointes
What hormones share a common alpha subunit

2. Brenners tumor
S cells
Bisphosphonates MofA
enzyme used to conjugate bilirubin
ovarian tumor that resembles bladder epithelium

3. Motor
Where does the lateral corticospinal decussate?
keratin filled cysts
GM2 ganglioside accumulation
VA/VL

4. PPAR- gamma receptor agonist - which causes improved target cell response to insulin
ambiguous nucleus
TZD (glitazones) MofA
most common breast cancer
vasculitis a/w Hep B

5. Premature detachment of placenta - painful bleeding in 3rd trimester
abruptio placentae
branching rods on oral infection
cough - conjunctivitis - coryza - fever
dose response curve change with competitive antagonist

6. Neutrophil chemotactic agent 'neutrophils arrive B4 others'
LTB4
ventral posterior nucleus - lateral part
tram - track on microscope
protease inhibitors MofA

7. Actinomyces
PTU
grossly black liver
sulfonylureas MofA
branching rods on oral infection

8. A few levels above the level of entry
paraventricular nucleus of hypothalamus
Where does the spinothalamic decussate?
barbituates withdrawal
myelinates multiple CNS axons

9. Hereditary spherocytosis
increased MCHC and hemolytic anemia
failure of endodermal development
inheritance pattern for all MENs
what cells secrete somatostatin

10. Yolk sac tumor
GM2 ganglioside accumulation
Schiller Duval bodies
3 tumors of MEN 2b
paraventricular nucleus of hypothalamus

11. PNH
vasculitis of infants and children - involving coronary arteries
hemosiderinurea and thrombosis
Where does the dorsal column decussate?
which nerve lifts the eyelid?

12. Inflammatory lesions of subq fat - usually on anterior shins. a/w infections
Schiller Duval bodies
erythema nodosum
optically clear nuclei (orphan annie)
contains ovarian vessels

13. Barbituates - carbamazapine - griseofulvin - phenytoin - quinidine - rifampin - St. John's wort
UMN signs
psammoma bodies
BCG PQRS
What thyroid pathology has an extremely tender thyroid gland

14. Decreases conversion
lysosomal storage disease a/w renal disease
PTU
SICK PEG
cancer arising from parafollicular C cells

15. Macconkey's agar
drug that blocks purine synthesis and is metabolized by xanthine oxidase
Shigella
thromboxane A2
tram - track on microscope

16. Fibrocystic
most common breast mass in pre - menopausal women
ovarian tumor with psammoma bodies
psammoma bodies
chromosome 4

17. DiGeorge
partial mole components
opioid withdrawal
lead antidote
failure of endodermal development

18. Amygdala
kluver bucy
dermatin sulfate accumulation
SICK PEG
Shigella

19. Oligodendrogila
epithelial
cells destroyed in MS
keratin filled cysts
branching rods on oral infection

20. Gauchers
alpha 1 anti - trypsin
beta glucocerebrosidase
dermatin sulfate accumulation
PTU

21. Sulfonamides - hydralazine - isonazid - procainamide - phenytoin
hemosiderinurea + thrombosis
Where does the lateral corticospinal decussate?
hemosiderinurea and thrombosis
drug induced lupus

22. Anti - TNF antibody - use for RA but watch out for latent TB!
infliximab
MofA Levothyroxine
mildly decreased UDPGT
beta glucocerebrosidase

23. Bromocriptine
most common breast mass in postmenopausal women
catalase positive coagulase negative
what inhibits prolactin secretion
may lead to multiple personalities

24. Invasive ductal CA
infliximab
may lead to multiple personalities
most common breast mass in postmenopausal women
TZD (glitazones) MofA

25. Decreased potency - increased Km
dose response curve change with competitive antagonist
spike and dome on microscope
S cells
I cells

26. Attachment of placenta to lower uterine segment
opioid withdrawal
placenta previa
psammoma bodies
hydrocele

27. Flumazenil
ventral posterior nucleus - medial part
benzos antidote
alpha L iduronidase
ovarian tumor with elevate hCG

28. HTN; XY will be a girl - XX will lack secondary sex char.
chromosome 4
catalase negative
kawasaki
17 alpha hydroxylase deficiency

29. Homocystienuria - Marfans
GFAP positive
probenecid
subluxation of lens
catalase positive coagulase negative

30. D cells of pancreas and gut
partial mole components
3 tumors of MEN 2b
benzos antidote
what cells secrete somatostatin

31. Meissner
lisch nodules
found in hairless skin
What oncogene is a/w MEN 2a/b
master clock for circadian rhythms

32. Marfans
floppy mitral valve dissecting aortic aneurysm - berry aneurysm
most common primary cardiac tumor in kiddos
treatment for SIADH
keratin filled cysts

33. Causes vasoconstriction (use for acute migraines)
floppy mitral valve dissecting aortic aneurysm - berry aneurysm
SICK PEG
sumatriptan
treatment of malignant hyperthermia

34. Fibroadenoma
dermatin sulfate accumulation
most common breast tumor in women under 25
P450 inducers
brain tumor with fried egg appearance

35. Membranous GN
spike and dome on microscope
ventral posterior nucleus - medial part
What hormones share a common alpha subunit
cells destroyed in MS

36. Pneumonia - URIs - STDS
ovarian tumor with elevate hCG
catalase negative
t - PA - streptokinase antidote
macrolides use (PUS)

37. Inhibits platelet aggregation - promotes vasodilation and decreases uterine tone
PGI2 (prostacyclin))
antibiotic with SE of eosinophilia
P450 Inhibitors
epithelial

38. Polyarteritis nodosa
microglia
vasculitis a/w Hep B
sulfonylureas MofA
tumor composed of cytotrophoblasts and syncytiotrophoblasts

39. Oligodendrioma
brain tumor with fried egg appearance
H. flu
Where does the lateral corticospinal decussate?
oligodendrioglia

40. Hemangioblastoma
LTB4
brain tumor with foamy cells and high vascularity
cancer associated with Hashimoto's thyroiditis
epithelial

41. G1/S & G2/M
lysosomal storage disease a/w renal disease
what checkpoint is p53 involved with?
sulfonylureas
schwann cells

42. PNH
hemosiderinurea + thrombosis
floppy mitral valve dissecting aortic aneurysm - berry aneurysm
glycine
thyroid cancer associtated with RET oncogene

43. Hemolysis - elevated LFTs - Low Platelets
first line for absence seizures
17 alpha hydroxylase deficiency
HELLP syndrome
x- linked recessive lysosomal storage diseases

44. Metachromatic leukodystrophy
P450 Inhibitors
lysosomal storage disease - demyelinating disease
Galactocerebrosidase deficiency
anti - epithelial antibodies

45. Medullary thyroid - pheochromocytoma - oral/intestinal ganglionueromatosis
3 tumors of MEN 2b
tumor with call - exner bodies
Addison's
SE: torsades de pointes

46. Legionella
silver stain of gram negative rods
heparin antidote
LTB4
copper - arsenic - gold antidote

47. Schwann cells
cells destroyed in Guillain Barre
abruptio placentae
eczema/recurrent infections/thrombocytopenia
metformin side effect

48. Cavernous hemangiomas in skin - mucosa & organs; autosomal dominant - a/w renal CA - hemangioblastoma in retina - brainstem & cerebellum
locus ceruleus
3 tumors of MEN 2a
probenecid
von Hippel Lindau disease

49. Babinski - weakness - increased reflexes & tone - spastic paralysis
most common testicular tumor
most common gyno malignancy
UMN signs
smoking emphysema

50. Superchiasmic nucleus
hydatidiform mole with crazy high hCG
Abciximab
5 alpha reductase deficiency
master clock for circadian rhythms

Can you answer 50 questions in 15 minutes?

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USMLE Pathophys

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