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USMLE Pathophys

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Neurofibromatosis
ependymal cells
lisch nodules
beta glucocerebrosidase
mitral valve prolapse - liver diseae - berry aneurysm

2. Ovarian bengin tumor...looks like bladder
brenner tumor
hippocampus
most common breast mass in postmenopausal women
master clock for circadian rhythms

3. Small diameter > large diameter; myelinated > unmyelinated
lead antidote
infliximab
order of nerve blockade
thymidylate synthase

4. Decreased follicles & estrogen with increased FSH & LH
Aschoff bodies
What are the hormone changes seen in menopause
locus ceruleus
opioid withdrawal

5. NE
locus ceruleus
benzos antidote
mitral valve prolapse - liver diseae - berry aneurysm
oligohydramnios

6. Niacins
deficiency of mannose phosphorylation
best effect on HDL
I cells
dorsal motor nucleus

7. Bilateral renal agenesis or posterior urethral valves in males
oligohydramnios
failure of endodermal development
plenta accreta
Galactocerebrosidase deficiency

8. Cant convert testosterone to DHT - ambiguous genitalia until puberty then penis at 12
barbituates withdrawal
5 alpha reductase deficiency
parietal cells
sulfonylureas

9. A/w esophageal/duodenal atresia and anencephaly
absent UTPGT
polyhydramnios
nucleoside reverse transcriptase inhibitors
cough - conjunctivitis - coryza - fever

10. Cells of BBB
HELLP syndrome
dermatin sulfate accumulation
catalase negative
astrocytes

11. Glucuronyl transferase
enzyme used to conjugate bilirubin
ventral posterior nucleus - lateral part
MofA of N- aceylcysteine
hippocampus

12. Alpha synuclein
treatment for SIADH
neutrophils fail to respond to chemotaxic stimuli
Lewy bodies composition
BCG PQRS

13. Decreased FEV/FVC ratio
supraoptic nucleus of hypothalamus
hallmark sign of COPD
MofA of N- aceylcysteine
first line for cardiogenic shock

14. Attachment of placenta to lower uterine segment
found in hairless skin
best effect on HDL
whats the V/Q at the base of the lung
placenta previa

15. Makes ADH
locus ceruleus
supraoptic nucleus of hypothalamus
D cells
contains ovarian vessels

16. Gonorrhea
opioid withdrawal
Where does the lateral corticospinal decussate?
cause of high pH vaginal discharge
thayer martin media

17. SCID
form multinucleated giant cells in the CNS when infected with HIV
child with eczema - coarse facial features - cold abscesses
smoking emphysema
chief cells

18. Fibroadenoma
most common breast tumor in women under 25
von Hippel Lindau disease
most common arrthymia
most common testicular tumor in infants and children up to 3 years of age

19. 2 sperm + empty egg (no fetal parts)
MofA Levothyroxine
complete mole components
low dose ASA effects - intermediate dose - high dose
alpha 1 anti - trypsin

20. Clopidogrel - ticoplidine
Shigella
infliximab
lisch nodules
blocks ADP receptors to inhibit platelet aggregation

21. Premature detachment of placenta - painful bleeding in 3rd trimester
strawberry tongue
abruptio placentae
which nerve lifts the eyelid?
whats the V/Q at the base of the lung

22. Superchiasmic nucleus
drug that blocks purine synthesis and is metabolized by xanthine oxidase
partial mole components
complete mole components
master clock for circadian rhythms

23. HTN - proteinuria - edema
low dose ASA effects - intermediate dose - high dose
lysosomal storage disease a/w renal disease
preeclampsia
treatment for SIADH

24. Job's or LAD
myelinates on PNS
neutrophils fail to respond to chemotaxic stimuli
microglia
lewy body composition

25. Trichomonas or bacterial vaginosis
deficiency of mannose phosphorylation
cause of high pH vaginal discharge
rate limiting step in carb digestion
what checkpoint is p53 involved with?

26. Complete
What anti - hypertensive drug has the side effect of first dose orthostatic hypotension
hydatidiform mole with crazy high hCG
mildly decreased UDPGT
abruptio placentae

27. Macconkey's agar
HELLP syndrome
oligodendrioglia
sulfonylureas side effect
Shigella

28. Decreased potency - increased Km
colchicine
alpha galacosidase A
dose response curve change with competitive antagonist
cause of increased myometrial excitability

29. Normal or candida
basal nucleus of Meynert
melanoma tumor marker
ovarian tumor with elevate hCG
cause of low pH vaginal discharge

30. Hemangioblastoma
brain tumor with foamy cells and high vascularity
preeclampsia
solitarius nucleus
SE: elevated LFTS - myositis

31. Protamine sulfate
blood supply for thalamus
TZD (glitazones) MofA
heparin antidote
preeclampsia

32. Leydig cell tumor
neutrophils fail to respond to chemotaxic stimuli
testicular tumor that can present with gynecomastia
found in hairless skin
metformin side effect

33. Amygdala
MofA of N- aceylcysteine
kluver bucy
raphe nucleus
brenner tumor

34. Antitoxin - penicillin - DPT vaccine
most common bacteria in GI tract
cause of LH surge
diphtheria treatment
drug that blocks purine synthesis and is metabolized by xanthine oxidase

35. Cocain and sumatriptan
PGI2 (prostacyclin))
Shigella
What causes coronary vasospasm as a SE?
Where does the spinothalamic decussate?

36. H. Influenza
gram + bacteria that requires NAD and hemin for growth
most common testicular tumor
supraoptic nucleus of hypothalamus
hippocampus

37. Oligodendrogila
cells destroyed in MS
3 tumors of MEN 1
contains ovarian vessels
opioids antidote

38. Sotalol - quinidine - cisapride
Where does the spinothalamic decussate?
Abciximab
SE: torsades de pointes
smoking emphysema

39. Oligodendroglia
may lead to multiple personalities
pt has extended expiratory phase
looks like fried eggs under histologic staining
midshaft break of humerus

40. Vibration - pressure
contains ovarian vessels
hemosiderinurea + thrombosis
von Hippel Lindau disease
pacinian

41. Impetigo
What are the hormone changes seen in menopause
cause of high pH vaginal discharge
honey crusted lesions common around nose/lips
protease inhibitors MofA

42. Hurlers
corneal clouding & MR
Yolk sac tumor produces...
SE: facial flushing
pigmented iris hamartomas - neural tumors

43. Dantrolene (prevents release of calcium from SR of muscle)
lead antidote
treatment of malignant hyperthermia
most common breast mass in pre - menopausal women
Addison's

44. Seborric keratosis
chief cells
keratin filled cysts
most common breast mass in postmenopausal women
polyhydramnios

45. Centriacinar
low dose ASA effects - intermediate dose - high dose
smoking emphysema
3 tumors of MEN 2a
meissners

46. Dopamine
MPTP exposure causes depletion of what NT?
SE: elevated LFTS - myositis
x- linked recessive lysosomal storage diseases
psammoma bodies

47. Staph epidermidis - staph sapro
intranuclear inclusions seen in herpes simplex encephalitis
catalase positive coagulase negative
UMN signs
hippocampus

48. BCG PQRS
P450 inducers
enzyme used to conjugate bilirubin
sturge weber syndrome
SICK PEG

49. Autosomal dominant
tram - track on microscope
found in hairless skin
inheritance pattern for all MENs
LTB4

50. Fabry's & Hunters
thymidylate synthase
dose response curve with noncompetitive antagonist
protease inhibitors MofA
x- linked recessive lysosomal storage diseases