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USMLE Pathophys

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Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Facial sensation (Make up on your face)
ventral posterior nucleus - medial part
brain tumor with foamy cells and high vascularity
infliximab
solitarius nucleus

2. Protamine sulfate
heparin antidote
brain tumor with psammona bodies
most common breast cancer
Yolk sac tumor produces...

3. HTN - proteinuria - edema
cause of malignant hyperthermia
sarcoma botyroides
preeclampsia
neutrophils fail to respond to chemotaxic stimuli

4. Niacins
best effect on HDL
tram - track on microscope
subluxation of lens
sturge weber syndrome

5. Granulosa cell tumor
tumor with call - exner bodies
iduronidase sulfatase
low dose ASA effects - intermediate dose - high dose
most common arrthymia

6. Vaginal carcinoma: spindle shaped tumor cells that are desmin positive
sarcoma botyroides
drug induced lupus
locus ceruleus
absent UTPGT

7. Dantrolene (prevents release of calcium from SR of muscle)
kawasaki
blocks ADP receptors to inhibit platelet aggregation
resembles an onion in cross section
treatment of malignant hyperthermia

8. Chocolate agar
honey crusted lesions common around nose/lips
testicular tumor that can present with gynecomastia
H. flu
psammoma bodies

9. Impetigo
LT C4 D4 E4
opioid withdrawal
honey crusted lesions common around nose/lips
HELLP syndrome

10. Motor
VA/VL
TZD (glitazones) MofA
treatment for SIADH
diphtheria treatment

11. Dobutamine
thyroid cancer associtated with RET oncogene
treatment for SIADH
first line for cardiogenic shock
order of nerve blockade

12. G1/S & G2/M
what checkpoint is p53 involved with?
What anti - hypertensive drug has the side effect of first dose orthostatic hypotension
leydig cell tumor
thyroid cancer associtated with RET oncogene

13. Inflammatory lesions of subq fat - usually on anterior shins. a/w infections
SICK PEG
erythema nodosum
rate limiting step in carb digestion
dose response curve with noncompetitive antagonist

14. Hurlers
sphingomyelinase deficiency
corneal clouding & MR
paraventricular nucleus of hypothalamus
G cells

15. H. Influenza
child with partial albinism - peripherial neuropathy - recurrent infections
deficiency of mannose phosphorylation
Shigella
gram + bacteria that requires NAD and hemin for growth

16. Meningioma
What thyroid pathology has an extremely tender thyroid gland
cells destroyed in Guillain Barre
brain tumor with psammona bodies
astrocytes

17. Ach
lysosomal storage disease - demyelinating disease
placenta previa
basal nucleus of Meynert
catalase negative

18. Actinomyces
master clock for circadian rhythms
PTU
branching rods on oral infection
sulfonylureas

19. NE
t - PA - streptokinase antidote
what cells secrete somatostatin
smoking emphysema
locus ceruleus

20. Premature detachment of placenta - painful bleeding in 3rd trimester
abruptio placentae
keratin filled cysts
heparin antidote
cause of LH surge

21. Primary biliary cirrhosis
diphtheria treatment
nucleoside reverse transcriptase inhibitors
anti - mitochondrial antibodies
keratin filled cysts

22. NF 1
pigmented iris hamartomas - neural tumors
polyhydramnios
parietal cells
keratin filled cysts

23. Penicillamine
chromosome 4
lisch nodules
currant jelly stool
copper - arsenic - gold antidote

24. Oligodendroglia
found in hairless skin
subluxation of lens
most common lysosomal storage disease
looks like fried eggs under histologic staining

25. Chronic gout. inhibits reabsorbtion of uric acid in PCT
probenecid
dose response curve change with competitive antagonist
crinkled paper cytoplasm
diphtheria treatment

26. ACE inhibitors
what cells secrete somatostatin
what checkpoint is p53 involved with?
inheritance pattern for all MENs
shown to slow progression of diabetic neuropathy

27. Normal or candida
hemangioblastomas of retina/cerebellum/medulla
MofA of N- aceylcysteine
lysosomal storage disease a/w renal disease
cause of low pH vaginal discharge

28. Streptococcus
eczema/recurrent infections/thrombocytopenia
alpha 1 anti - trypsin
catalase negative
ventral posterior nucleus - lateral part

29. Sulfonamides - Isonizid - Cimetidine - Ketoconazole - Erythromyicn - grapefruit juice - protease inhibitors
adenomyosis
cause of increased myometrial excitability
SICK PEG
papillary thyroid cancer

30. Yolk sac
hallmark sign of COPD
What oncogene is a/w MEN 2a/b
sarcoma botyroides
most common testicular tumor in infants and children up to 3 years of age

31. A few levels above the level of entry
Bisphosphonates MofA
Where does the spinothalamic decussate?
anti - mitochondrial antibodies
antibiotic with SE of eosinophilia

32. Estrogen (causes precocious puberty)
granulosa cell tumor secretes what?
myelinates multiple CNS axons
ovarian tumor with psammoma bodies
what meds treat malaria

33. Autosomal dominant
What anti - hypertensive drug has the side effect of first dose orthostatic hypotension
LT C4 D4 E4
FGFR3 mutation
inheritance pattern for all MENs

34. Chloroquine and primaquine
erythema nodosum
what meds treat malaria
S cells
metformin side effect

35. Macrolides
cause of LH surge
etanercept
antibiotic with SE of eosinophilia
benzos antidote

36. Bind viral gp41 subunit
absent UTPGT
macrolides use (PUS)
basal nucleus of Meynert
fusion inhibitors

37. Makes ADH
SE: facial flushing
sulfonylureas MofA
supraoptic nucleus of hypothalamus
rate limiting step in carb digestion

38. Legionella
11 beta hydroxylase deficiency
silver stain of gram negative rods
what nerve innervates the muscles of mastication?
GABA - glutamine

39. Seborric keratosis
SE: elevated LFTS - myositis
papillary thyroid cancer
keratin filled cysts
copper - arsenic - gold antidote

40. Decreases conversion
UMN signs
increased MCHC and hemolytic anemia
epithelial
PTU

41. Depolymerizes microtubules - impairing leukocyte chemotaxis and degranulation
increased MCHC and hemolytic anemia
von Hippel Lindau disease
t - PA - streptokinase antidote
colchicine

42. Fibrates
best effect of triglycerides/VLDL
branching rods on oral infection
oligodendrioglia
ambiguous nucleus

43. Centriacinar
metformin side effect
alpha 1 anti - trypsin
cancer arising from parafollicular C cells
smoking emphysema

44. Choriocarcinoma
shown to slow progression of diabetic neuropathy
tumor composed of cytotrophoblasts and syncytiotrophoblasts
corneal clouding & MR
failure of endodermal development

45. Pacinian
adenomyosis
resembles an onion in cross section
cancer associated with Hashimoto's thyroiditis
Where does the dorsal column decussate?

46. Cavernous hemangiomas in skin - mucosa & organs; autosomal dominant - a/w renal CA - hemangioblastoma in retina - brainstem & cerebellum
most common protozoal infection in US
What hormones share a common alpha subunit
oligodendrioglia
von Hippel Lindau disease

47. Somatostatin
D cells
oligodendrioglia
heparin antidote
hemosiderinurea and thrombosis

48. Demeclycocycline or water restriction
granulosa cell tumor secretes what?
pacinian
treatment for SIADH
optically clear nuclei (orphan annie)

49. Macconkey's agar
Shigella
tumor with call - exner bodies
pigmented iris hamartomas - neural tumors
kawasaki

50. Deficiency of aldosterone and cortisol

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USMLE Pathophys

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