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USMLE Pathophys

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Vibration - pressure
dose response curve change with competitive antagonist
pacinian
LTB4
supraoptic nucleus of hypothalamus

2. Choriocarcinoma
cause of low pH vaginal discharge
brain tumor with fried egg appearance
tumor composed of cytotrophoblasts and syncytiotrophoblasts
sarcoma botyroides

3. Pneumonia - URIs - STDS
palisading nuclei - locally invasive
cause of LH surge
Galactocerebrosidase deficiency
macrolides use (PUS)

4. Tay SaX
3 tumors of MEN 2b
heXosaminidase
shown to slow progression of diabetic neuropathy
schwann cells

5. Seborric keratosis
Yolk sac tumor produces...
keratin filled cysts
copper - arsenic - gold antidote
metformin side effect

6. CCK
brain tumor with perivascular pseudorosettes
I cells
hydrocele
crinkled paper cytoplasm

7. Pacinian
brain tumor with psammona bodies
what nerve innervates the muscles of mastication?
copper - arsenic - gold antidote
resembles an onion in cross section

8. Macrophages of the CNS
t - PA - streptokinase antidote
first line for cardiogenic shock
neutrophils fail to respond to chemotaxic stimuli
microglia

9. Placenta attached to myometrium
most common breast mass in pre - menopausal women
found in hairless skin
plenta accreta
protease inhibitors MofA

10. Sends autonomic fibers to heart
17 alpha hydroxylase deficiency
order of nerve blockade
dorsal motor nucleus
parietal cells

11. Criglar Najar
thymidylate synthase
absent UTPGT
schwann cells
enzyme used to conjugate bilirubin

12. Bruton's agammaglobulinemia
glycine
defective tyrosine kinase
enzyme used to conjugate bilirubin
plenta accreta

13. Facial sensation (Make up on your face)
LT C4 D4 E4
ventral posterior nucleus - medial part
hep B seropositivity in 30% of patients
cancer arising from parafollicular C cells

14. B. fragilis
most common bacteria in GI tract
found in hairless skin
cells destroyed in Guillain Barre
cells destroyed in MS

15. HTN - proteinuria - edema
preeclampsia
medial geniculate nucleus
plenta accreta
rate limiting step in carb digestion

16. Inhibitory in the brain - stimulatory in the brain
infliximab
floppy mitral valve dissecting aortic aneurysm - berry aneurysm
adenomyosis
GABA - glutamine

17. Demeclycocycline or water restriction
lysosomal storage disease a/w renal disease
erythema nodosum
treatment for SIADH
solitarius nucleus

18. Bilateral renal agenesis or posterior urethral valves in males
may lead to multiple personalities
cause of high pH vaginal discharge
oligohydramnios
dose response curve with noncompetitive antagonist

19. Decreased follicles & estrogen with increased FSH & LH
what checkpoint is p53 involved with?
precursor to GABA
What are the hormone changes seen in menopause
myelinates multiple CNS axons

20. Gilberts
resembles an onion in cross section
What causes coronary vasospasm as a SE?
smoking emphysema
mildly decreased UDPGT

21. Thryroxine replacement
GM2 ganglioside accumulation
MofA Levothyroxine
What anti - hypertensive drug has the side effect of first dose orthostatic hypotension
sulfonylureas side effect

22. Hypoglycemia
sulfonylureas side effect
precursor to GABA
low dose ASA effects - intermediate dose - high dose
t - PA - streptokinase antidote

23. Oculomotor
SE: facial flushing
hydatidiform mole with crazy high hCG
colchicine
which nerve lifts the eyelid?

24. Decreased potency - increased Km
tram - track on microscope
sulfonylureas
blood supply for thalamus
dose response curve change with competitive antagonist

25. Closes K+ channel on B cells causing depolarization and thus calcium influx which causes insulin release
anti - epithelial antibodies
ventral posterior nucleus - lateral part
sulfonylureas MofA
most common testicular tumor

26. Function as bronchoconstrictors - vasoconstrictors - sm mm contraction and increased vascular permability
most common breast mass in pre - menopausal women
ventral posterior nucleus - medial part
alpha 1 anti - trypsin
LT C4 D4 E4

27. Ethosuximide
SICK PEG
honey crusted lesions common around nose/lips
first line for absence seizures
MofA of N- aceylcysteine

28. Lactic acidosis
metformin side effect
cause of high pH vaginal discharge
S cells
pseudopalisading necrosis

29. Support - repair - potassium metabolism - remove excess NT - maintain BBB - marker is GFAP
macrolides use (PUS)
astrocytes
lewy body composition
etanercept

30. Bromocriptine
what inhibits prolactin secretion
oligodendrioglia
cells destroyed in Guillain Barre
beta glucocerebrosidase

31. Papillary CA of thyroid
raphe nucleus
optically clear nuclei (orphan annie)
looks like fried eggs under histologic staining
x- linked recessive lysosomal storage diseases

32. D cells of pancreas and gut
diphtheria treatment
grossly black liver
thymidylate synthase
what cells secrete somatostatin

33. Motor innervation of pharynx - larynx and upper esophagus
plenta accreta
oligodendrioglia
most common breast cancer
ambiguous nucleus

34. Memory
hippocampus
cells destroyed in Guillain Barre
whats the V/Q at the base of the lung
most common testicular tumor in infants and children up to 3 years of age

35. Attachment of placenta to lower uterine segment
placenta previa
supraoptic nucleus of hypothalamus
protease inhibitors MofA
cough - conjunctivitis - coryza - fever

36. Flumazenil
benzos antidote
ependymal cells
sulfonylureas
palisading nuclei - locally invasive

37. Primary hyperaldosteronism (HTN - hypokalemia - metabolic alkalosis)

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38. Serotonin
most common first line agent for septic shock
Shigella
most common protozoal infection in US
raphe nucleus

39. Depolymerizes microtubules - impairing leukocyte chemotaxis and degranulation
colchicine
protease inhibitors MofA
P450 inducers
3 tumors of MEN 1

40. HTN; XY will be a girl - XX will lack secondary sex char.
SICK PEG
17 alpha hydroxylase deficiency
LTB4
homer wright rosettes

41. Hemangioblastoma
schwann cells
order of nerve blockade
epithelial
brain tumor a/w von hipple - linadu syndrome

42. Gauchers
hydatidiform mole with crazy high hCG
beta glucocerebrosidase
BCG PQRS
VA/VL

43. HTN; masculinization
11 beta hydroxylase deficiency
3 tumors of MEN 2b
vasculitis a/w Hep B
barbituates withdrawal

44. Trigeminal
Aschoff bodies
what nerve innervates the muscles of mastication?
UMN signs
S cells

45. Kawasaki
hemosiderinurea + thrombosis
pigmented iris hamartomas - neural tumors
honey crusted lesions common around nose/lips
vasculitis of infants and children - involving coronary arteries

46. Hairless skin - dynamic fine touch
opioid withdrawal
alpha 1 anti - trypsin
meissners
branching rods on oral infection

47. Medulla
dose response curve change with competitive antagonist
leydig cell tumor
alpha L iduronidase
Where does the dorsal column decussate?

48. PPAR- gamma receptor agonist - which causes improved target cell response to insulin
hydatidiform mole with crazy high hCG
rabies
Aschoff bodies
TZD (glitazones) MofA

49. Actinomyces
most common testicular tumor in infants and children up to 3 years of age
branching rods on oral infection
What are the hormone changes seen in menopause
mildly decreased UDPGT

50. Regenerates glutathione
antibiotic with SE of eosinophilia
MofA of N- aceylcysteine
grossly black liver
enzyme used to conjugate bilirubin