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USMLE Pathophys

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Damaged in Guillian Barre
cause of high pH vaginal discharge
most common breast mass in pre - menopausal women
may lead to multiple personalities
schwann cells

2. Bilateral renal agenesis or posterior urethral valves in males
tumor with call - exner bodies
oligohydramnios
ependymal cells
granulosa cell tumor secretes what?

3. Visceral sensory
brenner tumor
solitarius nucleus
Abciximab
Lewy bodies composition

4. Neutrophil chemotactic agent 'neutrophils arrive B4 others'
sarcoma botyroides
LTB4
What artery causes locked in syndrome
form multinucleated giant cells in the CNS when infected with HIV

5. Decreases platelet aggregation - anti - pyretic and analgesic - high dose is anti - inflammatory
whats the V/Q at the base of the lung
3 tumors of MEN 2b
shown to slow progression of diabetic neuropathy
low dose ASA effects - intermediate dose - high dose

6. Centriacinar
tumor composed of cytotrophoblasts and syncytiotrophoblasts
smoking emphysema
catalase negative
oligodendrioglia

7. Granulosa cell tumor
MofA Levothyroxine
tumor with call - exner bodies
alpha L iduronidase
child with eczema - coarse facial features - cold abscesses

8. Inhibits viral assembly
beta glucocerebrosidase
5 alpha reductase deficiency
protease inhibitors MofA
kawasaki

9. 5- fluorouracil
Where does the lateral corticospinal decussate?
thymidylate synthase
Where does the dorsal column decussate?
order of nerve blockade

10. Inhibits osteoclastic activity
Bisphosphonates MofA
eczema/recurrent infections/thrombocytopenia
branching rods on oral infection
inheritance pattern for all MENs

11. CCK
cancer associated with Hashimoto's thyroiditis
most common testicular tumor
cells destroyed in Guillain Barre
I cells

12. Anxiety - insomnia - sweating - dilated pupils - piloerection - rhinorrhea
S cells
basal nucleus of Meynert
opioid withdrawal
beta glucocerebrosidase

13. Chloroquine and primaquine
x- linked recessive lysosomal storage diseases
what meds treat malaria
crinkled paper cytoplasm
PGI2 (prostacyclin))

14. Amygdala
MofA of N- aceylcysteine
ovarian tumor with elevate hCG
epithelial
kluver bucy

15. Mucocutaneous lymph node syndrome - necrotizing vasculitis - coronary aneurysms - strawberry tongue
currant jelly stool
heXosaminidase
kawasaki
GM2 ganglioside accumulation

16. Visual (Lateral for Light)
glycine
placenta previa
alpha galacosidase A
Lateral geniculate nucleus

17. Makes ADH
supraoptic nucleus of hypothalamus
nucleoside reverse transcriptase inhibitors
grossly black liver
what meds treat malaria

18. Obstructive - COPD
what nerve innervates the muscles of mastication?
most common breast mass in pre - menopausal women
pacinian
pt has extended expiratory phase

19. Oculomotor
alpha galacosidase A
mitral valve prolapse - liver diseae - berry aneurysm
sulfonylureas
which nerve lifts the eyelid?

20. Kawasaki (treat with high dose aspirin)
strawberry tongue
found in hairless skin
sclerosing adenosis
LT C4 D4 E4

21. Astrocytoma & glioblastoma multiforme
drug induced lupus
GFAP positive
dose response curve change with competitive antagonist
TZD (glitazones) MofA

22. Intussception
currant jelly stool
SICK PEG
alpha galacosidase A
brain tumor with psammona bodies

23. Oligodendroglia
Where does the dorsal column decussate?
precursor to GABA
looks like fried eggs under histologic staining
currant jelly stool

24. S-100
melanoma tumor marker
lysosomal storage disease a/w renal disease
tram - track on microscope
most common gyno malignancy

25. Alpha feto protein
looks like fried eggs under histologic staining
tram - track on microscope
macrolides use (PUS)
Yolk sac tumor produces...

26. Homocystienuria - Marfans
subluxation of lens
optically clear nuclei (orphan annie)
drug that blocks purine synthesis and is metabolized by xanthine oxidase
homer wright rosettes

27. BCG PQRS
P450 inducers
looks like fried eggs under histologic staining
smoking emphysema
astrocytes

28. Sulfonamides - hydralazine - isonazid - procainamide - phenytoin
drug induced lupus
shown to slow progression of diabetic neuropathy
first line for cardiogenic shock
sphingomyelinase deficiency

29. Hemolysis - elevated LFTs - Low Platelets
HELLP syndrome
iduronidase sulfatase
complete mole components
MofA of N- aceylcysteine

30. Brenners tumor
hep B seropositivity in 30% of patients
increased MCHC and hemolytic anemia
ovarian tumor that resembles bladder epithelium
What oncogene is a/w MEN 2a/b

31. NE
adenomyosis
most common first line agent for septic shock
most common lysosomal storage disease
kawasaki

32. 6- MP
S cells
drug that blocks purine synthesis and is metabolized by xanthine oxidase
absent UTPGT
pacinian

33. Hereditary spherocytosis
sulfonylureas side effect
increased MCHC and hemolytic anemia
antibiotic with SE of eosinophilia
follicular

34. Sotalol - quinidine - cisapride
SE: torsades de pointes
oligodendrioglia
Shigella
eczema/recurrent infections/thrombocytopenia

35. Alpha synuclein
complete mole components
UMN signs
lewy body composition
hemangioblastomas of retina/cerebellum/medulla

36. Pacinian
GFAP positive
resembles an onion in cross section
astrocytes
myelinates multiple CNS axons

37. Rheumatic fever
Aschoff bodies
ovarian tumor that resembles bladder epithelium
What causes coronary vasospasm as a SE?
Conn's syndrome

38. Choriocarcinoma
tumor composed of cytotrophoblasts and syncytiotrophoblasts
probenecid
ovarian tumor with elevate hCG
hallmark sign of COPD

39. Pepsin
chief cells
cells destroyed in MS
What are the hormone changes seen in menopause
lisch nodules

40. Increased acini and intralobular fibrosis
sclerosing adenosis
sumatriptan
crinkled paper cytoplasm
gram + bacteria that requires NAD and hemin for growth

41. Secretin
preeclampsia
P450 Inhibitors
hemosiderinurea + thrombosis
S cells

42. Gauchers
mitral valve prolapse - liver diseae - berry aneurysm
MofA Levothyroxine
sulfonylureas MofA
crinkled paper cytoplasm

43. Suspensory ligament of ovaries
sumatriptan
TZD (glitazones) MofA
contains ovarian vessels
absent UTPGT

44. Fibrates/statins
hemangioblastomas of retina/cerebellum/medulla
Schiller Duval bodies
SE: elevated LFTS - myositis
What thyroid pathology has an extremely tender thyroid gland

45. Cell type involved in most ovarian tumors
MofA Levothyroxine
tumor with call - exner bodies
epithelial
antibiotic with SE of eosinophilia

46. Chediak - Higashi
blocks ADP receptors to inhibit platelet aggregation
what nerve innervates the muscles of mastication?
child with partial albinism - peripherial neuropathy - recurrent infections
shown to slow progression of diabetic neuropathy

47. Ethosuximide
low dose ASA effects - intermediate dose - high dose
first line for absence seizures
hemangioblastomas of retina/cerebellum/medulla
plenta accreta

48. I- cell disease
ventral posterior nucleus - medial part
deficiency of mannose phosphorylation
partial mole components
low dose ASA effects - intermediate dose - high dose

49. Barbituates - carbamazapine - griseofulvin - phenytoin - quinidine - rifampin - St. John's wort
BCG PQRS
locus ceruleus
child with partial albinism - peripherial neuropathy - recurrent infections
cough - conjunctivitis - coryza - fever

50. TSH - LH - FSH - hCG
abruptio placentae
cause of malignant hyperthermia
What hormones share a common alpha subunit
kawasaki