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USMLE Pathophys

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Visual (Lateral for Light)
medial geniculate nucleus
eczema/recurrent infections/thrombocytopenia
Lateral geniculate nucleus
ambiguous nucleus

2. Support - repair - potassium metabolism - remove excess NT - maintain BBB - marker is GFAP
3 tumors of MEN 2a
nucleoside reverse transcriptase inhibitors
leydig cell tumor
astrocytes

3. Trigeminal
first line for cardiogenic shock
what nerve innervates the muscles of mastication?
child with eczema - coarse facial features - cold abscesses
chromosome 4

4. Subacute (De Quervain's) thyroiditis
midshaft break of humerus
cough - conjunctivitis - coryza - fever
Schiller Duval bodies
What thyroid pathology has an extremely tender thyroid gland

5. Clopidogrel - ticoplidine
leydig cell tumor
blocks ADP receptors to inhibit platelet aggregation
resembles an onion in cross section
copper - arsenic - gold antidote

6. Decreased follicles & estrogen with increased FSH & LH
locus ceruleus
floppy mitral valve dissecting aortic aneurysm - berry aneurysm
What are the hormone changes seen in menopause
lewy body composition

7. Pacinian
GFAP positive
ambiguous nucleus
MofA of N- aceylcysteine
resembles an onion in cross section

8. Neurofibromatosis
hemangioblastomas of retina/cerebellum/medulla
t - PA - streptokinase antidote
lisch nodules
floppy mitral valve dissecting aortic aneurysm - berry aneurysm

9. Vaginal carcinoma: spindle shaped tumor cells that are desmin positive
sarcoma botyroides
lewy body composition
nucleoside reverse transcriptase inhibitors
kluver bucy

10. Basal cell carcinoma
palisading nuclei - locally invasive
macrolides use (PUS)
blood supply for thalamus
TZD (glitazones) MofA

11. Bilateral renal agenesis or posterior urethral valves in males
oligohydramnios
Shigella
dermatin sulfate accumulation
found in hairless skin

12. Wiscott - Aldrich
eczema/recurrent infections/thrombocytopenia
optically clear nuclei (orphan annie)
3 tumors of MEN 2a
first line for cardiogenic shock

13. Norepinephrine
dorsal motor nucleus
locus ceruleus
homer wright rosettes
sumatriptan

14. Depolymerizes microtubules - impairing leukocyte chemotaxis and degranulation
11 beta hydroxylase deficiency
hemosiderinurea + thrombosis
rabies
colchicine

15. Trichomonas or bacterial vaginosis
Abciximab
SICK PEG
D cells
cause of high pH vaginal discharge

16. Placenta attached to myometrium
contains ovarian vessels
x- linked recessive lysosomal storage diseases
plenta accreta
vasculitis of infants and children - involving coronary arteries

17. Impetigo
hemosiderinurea and thrombosis
rate limiting step in carb digestion
honey crusted lesions common around nose/lips
treatment of malignant hyperthermia

18. Marfans
macrolides use (PUS)
tumor with call - exner bodies
SE: facial flushing
floppy mitral valve dissecting aortic aneurysm - berry aneurysm

19. Inhibits osteoclastic activity
most common breast mass in postmenopausal women
enzyme used to conjugate bilirubin
lysosomal storage disease a/w renal disease
Bisphosphonates MofA

20. Intussception
crinkled paper cytoplasm
SICK PEG
currant jelly stool
child with eczema - coarse facial features - cold abscesses

21. Dobutamine
cancer associated with Hashimoto's thyroiditis
sclerosing adenosis
first line for cardiogenic shock
medial geniculate nucleus

22. Schwann cells
myelinates on PNS
dermatin sulfate accumulation
lysosomal storage disease a/w renal disease
SICK PEG

23. Causes vasoconstriction (use for acute migraines)
treatment for SIADH
sumatriptan
Conn's syndrome
abruptio placentae

24. Hairless skin - dynamic fine touch
most common protozoal infection in US
meissners
supraoptic nucleus of hypothalamus
antibiotic with SE of eosinophilia

25. Closes K+ channel on B cells causing depolarization and thus calcium influx which causes insulin release
sulfonylureas MofA
mitral valve prolapse - liver diseae - berry aneurysm
strawberry tongue
What thyroid pathology has an extremely tender thyroid gland

26. Gonorrhea
pt has extended expiratory phase
thayer martin media
SE: torsades de pointes
crinkled paper cytoplasm

27. Hypoglycemia
crinkled paper cytoplasm
sulfonylureas side effect
P450 inducers
probenecid

28. HTN; XY will be a girl - XX will lack secondary sex char.
17 alpha hydroxylase deficiency
P450 inducers
Lateral geniculate nucleus
antibiotic with SE of eosinophilia

29. Homocystienuria - Marfans
lisch nodules
drug induced lupus
hydatidiform mole with crazy high hCG
subluxation of lens

30. Oculomotor
precursor to GABA
Shigella
which nerve lifts the eyelid?
midshaft break of humerus

31. Rheumatic fever
child with eczema - coarse facial features - cold abscesses
Aschoff bodies
x- linked recessive lysosomal storage diseases
PGI2 (prostacyclin))

32. Macrolides
antibiotic with SE of eosinophilia
microglia
inheritance pattern for all MENs
GM2 ganglioside accumulation

33. Lactic acidosis
low dose ASA effects - intermediate dose - high dose
Galactocerebrosidase deficiency
metformin side effect
mitral valve prolapse - liver diseae - berry aneurysm

34. Protamine sulfate
heparin antidote
GM2 ganglioside accumulation
MofA Levothyroxine
chief cells

35. Oligodendoglia
may lead to multiple personalities
psammoma bodies
best effect on HDL
myelinates multiple CNS axons

36. PPAR- gamma receptor agonist - which causes improved target cell response to insulin
child with eczema - coarse facial features - cold abscesses
What thyroid pathology has an extremely tender thyroid gland
preeclampsia
TZD (glitazones) MofA

37. Decreased efficacy - decreased Vmax
dose response curve with noncompetitive antagonist
cough - conjunctivitis - coryza - fever
most common primary cardiac tumor in kiddos
sulfonylureas side effect

38. Dissociative
3 tumors of MEN 2a
may lead to multiple personalities
What hormones share a common alpha subunit
hippocampus

39. Centriacinar
partial mole components
smoking emphysema
catalase positive coagulase negative
drug that blocks purine synthesis and is metabolized by xanthine oxidase

40. Streptococcus
treatment for SIADH
most common protozoal infection in US
von Hippel Lindau disease
catalase negative

41. Tay Sachs
cause of LH surge
anti - platelet antibodies
mildly decreased UDPGT
GM2 ganglioside accumulation

42. Oligosaccaride hydrolase
protease inhibitors MofA
rate limiting step in carb digestion
what nerve innervates the muscles of mastication?
copper - arsenic - gold antidote

43. Hemangioblastoma
What hormones share a common alpha subunit
vasculitis of infants and children - involving coronary arteries
heparin antidote
brain tumor with foamy cells and high vascularity

44. Cocain and sumatriptan
smoking emphysema
MofA Levothyroxine
drug induced lupus
What causes coronary vasospasm as a SE?

45. Fibrates
best effect of triglycerides/VLDL
keratin filled cysts
MofA Levothyroxine
tumor with call - exner bodies

46. Hereditary spherocytosis
master clock for circadian rhythms
thayer martin media
absent UTPGT
increased MCHC and hemolytic anemia

47. H. Influenza
currant jelly stool
partial mole components
gram + bacteria that requires NAD and hemin for growth
What causes coronary vasospasm as a SE?

48. D cells of pancreas and gut
what cells secrete somatostatin
D cells
oligodendrioglia
fusion inhibitors

49. Motor
SE: elevated LFTS - myositis
basal nucleus of Meynert
may lead to multiple personalities
VA/VL

50. SICK PEG
heparin antidote
P450 Inhibitors
first line for cardiogenic shock
MofA of N- aceylcysteine