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USMLE Pathophys

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Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Masculinization - hypovolemic shock
treatment for SIADH
21 hydroxylase deficiency
most common protozoal infection in US
Conn's syndrome

2. Inhibitory in the brain - stimulatory in the brain
most common testicular tumor
inheritance pattern for all MENs
GABA - glutamine
x- linked recessive lysosomal storage diseases

3. Weakness - atrophy - fasiculations - decreased reflexes & tone
schwann cells
LMN signs
most common testicular tumor
papillary thyroid cancer

4. Medullary thyroid - pheochromocytoma - parathryoid
SE: facial flushing
3 tumors of MEN 2a
cancer arising from parafollicular C cells
gram + bacteria that requires NAD and hemin for growth

5. Serotonin
sclerosing adenosis
alpha galacosidase A
raphe nucleus
anti - mitochondrial antibodies

6. Meningioma
brain tumor with psammona bodies
intranuclear inclusions seen in herpes simplex encephalitis
most common protozoal infection in US
Lateral geniculate nucleus

7. 2 sperm + empty egg (no fetal parts)
S cells
sulfonylureas side effect
ovarian tumor with elevate hCG
complete mole components

8. Kawasaki (treat with high dose aspirin)
cancer associated with Hashimoto's thyroiditis
strawberry tongue
H. flu
hallmark sign of COPD

9. Achondroplasia
heparin antidote
FGFR3 mutation
most common breast mass in pre - menopausal women
basal nucleus of Meynert

10. Inhibits platelet aggregation - promotes vasodilation and decreases uterine tone
midshaft break of humerus
PGI2 (prostacyclin))
Galactocerebrosidase deficiency
treatment for SIADH

11. HTN - proteinuria - edema
first line for cardiogenic shock
brain tumor with fried egg appearance
preeclampsia
hemosiderinurea and thrombosis

12. Inhibits osteoclastic activity
Bisphosphonates MofA
myelinates multiple CNS axons
What anti - hypertensive drug has the side effect of first dose orthostatic hypotension
Yolk sac tumor produces...

13. Decreases conversion
most common gyno malignancy
antibody against philadelphia chromosome
vasculitis of infants and children - involving coronary arteries
PTU

14. Gonorrhea
von Hippel Lindau disease
best effect of triglycerides/VLDL
thayer martin media
sarcoma botyroides

15. Cowdry type A inclusions
thayer martin media
leydig cell tumor
intranuclear inclusions seen in herpes simplex encephalitis
What artery causes locked in syndrome

16. Niacin
papillary thyroid cancer
silver stain of gram negative rods
SE: facial flushing
kawasaki

17. Pemphigus vulgaris
anti - epithelial antibodies
most common breast cancer
I cells
basal nucleus of Meynert

18. SICK PEG
silver stain of gram negative rods
P450 Inhibitors
von Hippel Lindau disease
x- linked recessive lysosomal storage diseases

19. Makes ADH
What are the hormone changes seen in menopause
supraoptic nucleus of hypothalamus
cancer associated with Hashimoto's thyroiditis
Where does the lateral corticospinal decussate?

20. ITP
GFAP positive
pseudopalisading necrosis
anti - platelet antibodies
colchicine

21. D cells of pancreas and gut
absent UTPGT
what cells secrete somatostatin
Lewy bodies composition
treatment for SIADH

22. Estrogen
dermatin sulfate accumulation
cause of LH surge
anti - epithelial antibodies
benzos antidote

23. Support - repair - potassium metabolism - remove excess NT - maintain BBB - marker is GFAP
astrocytes
sarcoma botyroides
hemosiderinurea + thrombosis
Lateral geniculate nucleus

24. Ependymoma
placenta previa
brain tumor with perivascular pseudorosettes
most common protozoal infection in US
which nerve lifts the eyelid?

25. Atrial fibrillation
dose response curve with noncompetitive antagonist
hep B seropositivity in 30% of patients
most common arrthymia
MofA of N- aceylcysteine

26. Rhabdomyoma
most common primary cardiac tumor in kiddos
Where does the spinothalamic decussate?
anti - mitochondrial antibodies
cause of high pH vaginal discharge

27. Macrolides
microglia
blood supply for thalamus
MPTP exposure causes depletion of what NT?
antibiotic with SE of eosinophilia

28. 6- mecaptopurine (metabolized by xanthine oxidase)
MofA Levothyroxine
floppy mitral valve dissecting aortic aneurysm - berry aneurysm
corneal clouding & MR
bocks PRPP synthetase to block purine synthesis

29. Niacins
lewy body composition
best effect on HDL
sclerosing adenosis
hep B seropositivity in 30% of patients

30. Inflammatory lesions of subq fat - usually on anterior shins. a/w infections
Where does the lateral corticospinal decussate?
optically clear nuclei (orphan annie)
TZD (glitazones) MofA
erythema nodosum

31. Somatostatin
rate limiting step in carb digestion
D cells
sturge weber syndrome
21 hydroxylase deficiency

32. Intussception
currant jelly stool
intranuclear inclusions seen in herpes simplex encephalitis
TZD (glitazones) MofA
beta glucocerebrosidase

33. Hurlers
alpha L iduronidase
barbituates withdrawal
hydatidiform mole with crazy high hCG
cause of low pH vaginal discharge

34. Hemolysis - elevated LFTs - Low Platelets
copper - arsenic - gold antidote
what cells secrete somatostatin
HELLP syndrome
x- linked recessive lysosomal storage diseases

35. Bilateral renal agenesis or posterior urethral valves in males
floppy mitral valve dissecting aortic aneurysm - berry aneurysm
cells destroyed in MS
oligohydramnios
granulosa cell tumor secretes what?

36. Bromocriptine
eczema/recurrent infections/thrombocytopenia
what inhibits prolactin secretion
copper - arsenic - gold antidote
diphtheria treatment

37. Attachment of placenta to lower uterine segment
Aschoff bodies
ovarian tumor that resembles bladder epithelium
placenta previa
intranuclear inclusions seen in herpes simplex encephalitis

38. Autosomal dominant
Aschoff bodies
barbituates withdrawal
cause of LH surge
inheritance pattern for all MENs

39. Obstructive - COPD
pt has extended expiratory phase
inheritance pattern for all MENs
best effect on HDL
schwann cells

40. Endometrial CA
GABA - glutamine
leydig cell tumor
most common gyno malignancy
honey crusted lesions common around nose/lips

41. Trichomonas or bacterial vaginosis
keratin filled cysts
myelinates on PNS
Shigella
cause of high pH vaginal discharge

42. Dantrolene (prevents release of calcium from SR of muscle)
alpha L iduronidase
treatment of malignant hyperthermia
whats the V/Q at the apex of the lung
LTB4

43. BCG PQRS
metformin side effect
opioids antidote
P450 inducers
alpha 1 anti - trypsin

44. Aplastic anemia - rash - agranulocytosis
propylthiouracil side effects
17 alpha hydroxylase deficiency
sclerosing adenosis
whats the V/Q at the apex of the lung

45. Deficiency of aldosterone and cortisol

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46. Anti - TNF antibody - use for RA but watch out for latent TB!
alpha galacosidase A
infliximab
hippocampus
von Hippel Lindau disease

47. S-100
cancer arising from parafollicular C cells
melanoma tumor marker
eczema/recurrent infections/thrombocytopenia
copper - arsenic - gold antidote

48. Glioblastoma multiforme
MPTP exposure causes depletion of what NT?
melanoma tumor marker
pseudopalisading necrosis
midshaft break of humerus

49. Lymphoma

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50. Choriocarcinoma or dysgerminoma
what meds treat malaria
chromosome 4
ovarian tumor with elevate hCG
floppy mitral valve dissecting aortic aneurysm - berry aneurysm

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USMLE Pathophys

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