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USMLE Pathophys

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Schwann cells
vasculitis of infants and children - involving coronary arteries
cells destroyed in Guillain Barre
brenner tumor
strawberry tongue

2. Choriocarcinoma or dysgerminoma
what meds treat malaria
brenner tumor
sarcoma botyroides
ovarian tumor with elevate hCG

3. Endometrial glands inside myometrium
adenomyosis
Yolk sac tumor produces...
lewy body composition
SE: torsades de pointes

4. Pneumonia - URIs - STDS
papillary thyroid cancer
kluver bucy
macrolides use (PUS)
cause of high pH vaginal discharge

5. S-100
sumatriptan
diphtheria treatment
LTB4
melanoma tumor marker

6. Basal cell carcinoma
palisading nuclei - locally invasive
ovarian tumor with psammoma bodies
mitral valve prolapse - liver diseae - berry aneurysm
deficiency of mannose phosphorylation

7. Demeclycocycline or water restriction
most common first line agent for septic shock
P450 Inhibitors
colchicine
treatment for SIADH

8. Anxiety - insomnia - sweating - dilated pupils - piloerection - rhinorrhea
5 alpha reductase deficiency
leydig cell tumor
opioid withdrawal
von Hippel Lindau disease

9. Neutrophil chemotactic agent 'neutrophils arrive B4 others'
S cells
LTB4
meissners
lysosomal storage disease - demyelinating disease

10. Primary hyperaldosteronism (HTN - hypokalemia - metabolic alkalosis)

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11. Bromocriptine
whats the V/Q at the apex of the lung
MofA of N- aceylcysteine
chromosome 4
what inhibits prolactin secretion

12. Aminocaproic acid
medial geniculate nucleus
follicular
eczema/recurrent infections/thrombocytopenia
t - PA - streptokinase antidote

13. H. Influenza
3 tumors of MEN 2a
gram + bacteria that requires NAD and hemin for growth
strawberry tongue
ventral posterior nucleus - medial part

14. Rhabdomyoma
anti - epithelial antibodies
ovarian tumor that resembles bladder epithelium
most common primary cardiac tumor in kiddos
G cells

15. Masculinization - hypovolemic shock
21 hydroxylase deficiency
x- linked recessive lysosomal storage diseases
paraventricular nucleus of hypothalamus
What artery causes locked in syndrome

16. PNH
hemosiderinurea + thrombosis
lead antidote
follicular
brain tumor with psammona bodies

17. Bind viral gp41 subunit
von Hippel Lindau disease
first line for absence seizures
fusion inhibitors
MofA of N- aceylcysteine

18. Ovarian bengin tumor...looks like bladder
brenner tumor
brain tumor a/w von hipple - linadu syndrome
treatment of malignant hyperthermia
cough - conjunctivitis - coryza - fever

19. Medulla
G cells
Where does the lateral corticospinal decussate?
treatment of malignant hyperthermia
complete mole components

20. HTN; masculinization
best effect on HDL
11 beta hydroxylase deficiency
papillary thyroid cancer
rabies

21. Primary biliary cirrhosis
mitral valve prolapse - liver diseae - berry aneurysm
anti - mitochondrial antibodies
SE: facial flushing
defective tyrosine kinase

22. Meningioma
brain tumor with psammona bodies
hydatidiform mole with crazy high hCG
UMN signs
thyroid cancer associtated with RET oncogene

23. Alpha synuclein
Lewy bodies composition
form multinucleated giant cells in the CNS when infected with HIV
S cells
meissners

24. Inhibitory in the brain - stimulatory in the brain
copper - arsenic - gold antidote
21 hydroxylase deficiency
sulfonylureas side effect
GABA - glutamine

25. Medullary
opioids antidote
increased MCHC and hemolytic anemia
pseudopalisading necrosis
cancer arising from parafollicular C cells

26. Sulfonamides - Isonizid - Cimetidine - Ketoconazole - Erythromyicn - grapefruit juice - protease inhibitors
SICK PEG
SE: facial flushing
catalase negative
corneal clouding & MR

27. Oligodendrioma
most common lysosomal storage disease
brain tumor with fried egg appearance
SE: elevated LFTS - myositis
barbituates withdrawal

28. Most common type of thyroid cancer
LMN signs
papillary thyroid cancer
bocks PRPP synthetase to block purine synthesis
grossly black liver

29. Fabry's
most common testicular tumor in infants and children up to 3 years of age
lysosomal storage disease a/w renal disease
rate limiting step in carb digestion
What thyroid pathology has an extremely tender thyroid gland

30. PPAR- gamma receptor agonist - which causes improved target cell response to insulin
What artery causes locked in syndrome
locus ceruleus
papillary thyroid cancer
TZD (glitazones) MofA

31. Makes ADH
supraoptic nucleus of hypothalamus
sclerosing adenosis
Conn's syndrome
microglia

32. Decreased follicles & estrogen with increased FSH & LH
What are the hormone changes seen in menopause
homer wright rosettes
may lead to multiple personalities
palisading nuclei - locally invasive

33. Hemangioblastoma
t - PA - streptokinase antidote
brain tumor with foamy cells and high vascularity
plenta accreta
most common testicular tumor in infants and children up to 3 years of age

34. Niemann Pick
brain tumor with foamy cells and high vascularity
sphingomyelinase deficiency
Shigella
Addison's

35. Function as bronchoconstrictors - vasoconstrictors - sm mm contraction and increased vascular permability
order of nerve blockade
alpha galacosidase A
floppy mitral valve dissecting aortic aneurysm - berry aneurysm
LT C4 D4 E4

36. Tay Sachs
GM2 ganglioside accumulation
ovarian tumor that resembles bladder epithelium
keratin filled cysts
thymidylate synthase

37. PNH
glycine
hemosiderinurea and thrombosis
midshaft break of humerus
most common breast cancer

38. Negri bodies
rabies
3 tumors of MEN 2b
enzyme used to conjugate bilirubin
child with partial albinism - peripherial neuropathy - recurrent infections

39. Regenerates glutathione
parietal cells
intranuclear inclusions seen in herpes simplex encephalitis
MofA of N- aceylcysteine
resembles an onion in cross section

40. Von Hippel Lindau
blood supply for thalamus
brain tumor with fried egg appearance
beta glucocerebrosidase
hemangioblastomas of retina/cerebellum/medulla

41. Decreases conversion
PTU
chief cells
most common lysosomal storage disease
form multinucleated giant cells in the CNS when infected with HIV

42. Cell type involved in most ovarian tumors
dose response curve change with competitive antagonist
Yolk sac tumor produces...
epithelial
x- linked recessive lysosomal storage diseases

43. Astrocytoma & glioblastoma multiforme
GFAP positive
treatment for SIADH
Schiller Duval bodies
What are the hormone changes seen in menopause

44. Pepsin
sturge weber syndrome
chief cells
heparin antidote
colchicine

45. Achondroplasia
ependymal cells
dorsal motor nucleus
follicular
FGFR3 mutation

46. ACE inhibitors
Where does the dorsal column decussate?
shown to slow progression of diabetic neuropathy
gram + bacteria that requires NAD and hemin for growth
neutrophils fail to respond to chemotaxic stimuli

47. Mucocutaneous lymph node syndrome - necrotizing vasculitis - coronary aneurysms - strawberry tongue
opioid withdrawal
kawasaki
cause of malignant hyperthermia
absent UTPGT

48. Oligodendrogila
drug induced lupus
MofA of N- aceylcysteine
adenomyosis
cells destroyed in MS

49. Causes vasoconstriction (use for acute migraines)
drug induced lupus
What hormones share a common alpha subunit
sumatriptan
colchicine

50. Ach
basal nucleus of Meynert
astrocytes
beta glucocerebrosidase
whats the V/Q at the base of the lung