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USMLE Pathophys

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Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Somatostatin
D cells
ependymal cells
SE: facial flushing
medial geniculate nucleus

2. Decreases platelet aggregation - anti - pyretic and analgesic - high dose is anti - inflammatory
5 alpha reductase deficiency
bocks PRPP synthetase to block purine synthesis
low dose ASA effects - intermediate dose - high dose
tumor with call - exner bodies

3. SCID
astrocytes
alpha L iduronidase
child with eczema - coarse facial features - cold abscesses
Yolk sac tumor produces...

4. HTN; masculinization
D cells
11 beta hydroxylase deficiency
inheritance pattern for all MENs
oligodendrioglia

5. Inhibits platelet aggregation - promotes vasodilation and decreases uterine tone
hydrocele
VA/VL
PGI2 (prostacyclin))
gram + bacteria that requires NAD and hemin for growth

6. Macconkey's agar
Shigella
branching rods on oral infection
hydatidiform mole with crazy high hCG
order of nerve blockade

7. Fibroadenoma
What are the hormone changes seen in menopause
most common breast tumor in women under 25
anti - platelet antibodies
What anti - hypertensive drug has the side effect of first dose orthostatic hypotension

8. Causes vasoconstriction (use for acute migraines)
MofA of N- aceylcysteine
cause of LH surge
hippocampus
sumatriptan

9. Membranoproliferative GN
brain tumor with foamy cells and high vascularity
Yolk sac tumor produces...
tram - track on microscope
SE: facial flushing

10. Thryroxine replacement
supraoptic nucleus of hypothalamus
sturge weber syndrome
MofA Levothyroxine
silver stain of gram negative rods

11. Fabrys
sturge weber syndrome
alpha galacosidase A
thromboxane A2
resembles an onion in cross section

12. Fabry's
microglia
tram - track on microscope
lysosomal storage disease a/w renal disease
order of nerve blockade

13. Closes K+ channel on B cells causing depolarization and thus calcium influx which causes insulin release
currant jelly stool
abruptio placentae
sulfonylureas MofA
21 hydroxylase deficiency

14. Decreased FEV/FVC ratio
GABA - glutamine
hallmark sign of COPD
Schiller Duval bodies
grossly black liver

15. Autosomal dominant
inheritance pattern for all MENs
sumatriptan
basal nucleus of Meynert
ovarian tumor with elevate hCG

16. Medulla
cause of high pH vaginal discharge
increased MCHC and hemolytic anemia
UMN signs
Where does the lateral corticospinal decussate?

17. Invasive ductal CA
Galactocerebrosidase deficiency
leydig cell tumor
FGFR3 mutation
most common breast mass in postmenopausal women

18. Bind viral gp41 subunit
fusion inhibitors
cause of LH surge
treatment of malignant hyperthermia
Yolk sac tumor produces...

19. 6- MP
astrocytes
antibiotic with SE of eosinophilia
absent UTPGT
drug that blocks purine synthesis and is metabolized by xanthine oxidase

20. CCK
homer wright rosettes
What anti - hypertensive drug has the side effect of first dose orthostatic hypotension
nucleoside reverse transcriptase inhibitors
I cells

21. Body sensation
spike and dome on microscope
cause of malignant hyperthermia
ventral posterior nucleus - lateral part
ovarian tumor with psammoma bodies

22. Decreased potency - increased Km
dose response curve change with competitive antagonist
most common first line agent for septic shock
psammoma bodies
what meds treat malaria

23. Dissociative
lewy body composition
treatment for SIADH
chief cells
may lead to multiple personalities

24. Sotalol - quinidine - cisapride
catalase negative
SE: torsades de pointes
palisading nuclei - locally invasive
grossly black liver

25. PNH
metformin side effect
hemosiderinurea and thrombosis
t - PA - streptokinase antidote
raphe nucleus

26. Kawasaki
cells destroyed in MS
kluver bucy
corneal clouding & MR
vasculitis of infants and children - involving coronary arteries

27. Primary biliary cirrhosis
myelinates multiple CNS axons
anti - mitochondrial antibodies
protease inhibitors MofA
testicular tumor that can present with gynecomastia

28. Vaginal carcinoma: spindle shaped tumor cells that are desmin positive
most common breast mass in postmenopausal women
sarcoma botyroides
basal nucleus of Meynert
bocks PRPP synthetase to block purine synthesis

29. Oligodendrioma
basal nucleus of Meynert
preeclampsia
brain tumor with fried egg appearance
alpha 1 anti - trypsin

30. Invasive ductal
rabies
Lateral geniculate nucleus
most common breast cancer
colchicine

31. Chocolate agar
palisading nuclei - locally invasive
brain tumor with psammona bodies
H. flu
D cells

32. Schwann cells
S cells
rabies
homer wright rosettes
myelinates on PNS

33. Damaged in multiple sclerosis
inheritance pattern for all MENs
HELLP syndrome
oligodendrioglia
increased MCHC and hemolytic anemia

34. Decreased follicles & estrogen with increased FSH & LH
GM2 ganglioside accumulation
neutrophils fail to respond to chemotaxic stimuli
psammoma bodies
What are the hormone changes seen in menopause

35. Protamine sulfate
heparin antidote
glycine
meissners
diphtheria treatment

36. Oligosaccaride hydrolase
ventral posterior nucleus - medial part
brenner tumor
what meds treat malaria
rate limiting step in carb digestion

37. Glucuronyl transferase
Where does the spinothalamic decussate?
enzyme used to conjugate bilirubin
intranuclear inclusions seen in herpes simplex encephalitis
drug induced lupus

38. Chronic gout. inhibits reabsorbtion of uric acid in PCT
lead antidote
colchicine
probenecid
What anti - hypertensive drug has the side effect of first dose orthostatic hypotension

39. Panacinar
SICK PEG
alpha 1 anti - trypsin
keratin filled cysts
hemangioblastomas of retina/cerebellum/medulla

40. A/w esophageal/duodenal atresia and anencephaly
polyhydramnios
3 tumors of MEN 1
testicular tumor that can present with gynecomastia
21 hydroxylase deficiency

41. Inhibitory in the SC
11 beta hydroxylase deficiency
catalase positive coagulase negative
glycine
alpha L iduronidase

42. Hypoglycemia
tumor with call - exner bodies
plenta accreta
sulfonylureas side effect
iduronidase sulfatase

43. Polyarteritis nodosa
keratin filled cysts
thromboxane A2
hep B seropositivity in 30% of patients
resembles an onion in cross section

44. Obstructive - COPD
antibiotic with SE of eosinophilia
pt has extended expiratory phase
intranuclear inclusions seen in herpes simplex encephalitis
oligodendrioglia

45. Impetigo
honey crusted lesions common around nose/lips
kluver bucy
GFAP positive
GABA - glutamine

46. Clopidogrel - ticoplidine
barbituates withdrawal
blocks ADP receptors to inhibit platelet aggregation
complete mole components
optically clear nuclei (orphan annie)

47. Posterior communicating - posterior cerebral - anterior choroidal arteries
looks like fried eggs under histologic staining
blood supply for thalamus
enzyme used to conjugate bilirubin
palisading nuclei - locally invasive

48. 2 sperm + 1 egg (fetal parts present)
may lead to multiple personalities
propylthiouracil side effects
tumor composed of cytotrophoblasts and syncytiotrophoblasts
partial mole components

49. Cause release of preformed insulin
sulfonylureas
anti - platelet antibodies
hippocampus
most common breast cancer

50. Fibrocystic
Shigella
Bisphosphonates MofA
most common breast mass in pre - menopausal women
treatment for SIADH

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USMLE Pathophys

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