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Test your basic knowledge |
USMLE Pathophys
Start Test
Study First
Subjects
:
health-sciences
,
usmle
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Babinski - weakness - increased reflexes & tone - spastic paralysis
mildly decreased UDPGT
low dose ASA effects - intermediate dose - high dose
LMN signs
UMN signs
2. Protamine sulfate
UMN signs
most common arrthymia
heparin antidote
bocks PRPP synthetase to block purine synthesis
3. Serotonin
Lateral geniculate nucleus
brenner tumor
raphe nucleus
fusion inhibitors
4. Oligodendrogila
Where does the spinothalamic decussate?
branching rods on oral infection
cells destroyed in MS
astrocytes
5. Cant convert testosterone to DHT - ambiguous genitalia until puberty then penis at 12
5 alpha reductase deficiency
testicular tumor that can present with gynecomastia
absent UTPGT
what inhibits prolactin secretion
6. Invasive ductal
treatment for SIADH
shown to slow progression of diabetic neuropathy
most common breast cancer
meissners
7. Medulla
Where does the dorsal column decussate?
tumor with call - exner bodies
solitarius nucleus
subluxation of lens
8. Marfans
grossly black liver
papillary thyroid cancer
alpha 1 anti - trypsin
floppy mitral valve dissecting aortic aneurysm - berry aneurysm
9. Decreases conversion
PTU
pseudopalisading necrosis
most common breast tumor in women under 25
beta glucocerebrosidase
10. Oligodendoglia
Where does the lateral corticospinal decussate?
von Hippel Lindau disease
I cells
myelinates multiple CNS axons
11. ADPKD
first line for cardiogenic shock
chief cells
mitral valve prolapse - liver diseae - berry aneurysm
deficiency of mannose phosphorylation
12. Inhibitory in the SC
glycine
cause of increased myometrial excitability
I cells
myelinates on PNS
13. Niacin
follicular
propylthiouracil side effects
SE: facial flushing
Bisphosphonates MofA
14. Prevents incorporation into host DNA
Lateral geniculate nucleus
bocks PRPP synthetase to block purine synthesis
nucleoside reverse transcriptase inhibitors
chromosome 4
15. Obstructive - COPD
sumatriptan
epithelial
pt has extended expiratory phase
hydatidiform mole with crazy high hCG
16. H. Influenza
gram + bacteria that requires NAD and hemin for growth
11 beta hydroxylase deficiency
absent UTPGT
raphe nucleus
17. Anxiety - seizures - delirium - life threatening CV collapse
contains ovarian vessels
5 alpha reductase deficiency
raphe nucleus
barbituates withdrawal
18. Vaginal carcinoma: spindle shaped tumor cells that are desmin positive
hemosiderinurea and thrombosis
sarcoma botyroides
most common breast mass in pre - menopausal women
most common gyno malignancy
19. Papillary CA of thyroid
optically clear nuclei (orphan annie)
pacinian
mildly decreased UDPGT
thromboxane A2
20. Chloroquine and primaquine
what meds treat malaria
crinkled paper cytoplasm
cancer arising from parafollicular C cells
GFAP positive
21. Secretin
dose response curve change with competitive antagonist
P450 Inhibitors
S cells
mildly decreased UDPGT
22. Hurlers
alpha L iduronidase
GM2 ganglioside accumulation
sclerosing adenosis
hydrocele
23. Port wine stains - ipsilateral leptomeningeal angioma; can cause glaucoma - seizures - hemipareis - and MR
PGI2 (prostacyclin))
resembles an onion in cross section
sturge weber syndrome
polyhydramnios
24. Gauchers
parietal cells
ovarian tumor with elevate hCG
beta glucocerebrosidase
PTU
25. 3
Bisphosphonates MofA
3 tumors of MEN 1
whats the V/Q at the apex of the lung
most common breast mass in postmenopausal women
26. HTN; masculinization
11 beta hydroxylase deficiency
plenta accreta
nucleoside reverse transcriptase inhibitors
Abciximab
27. Intrinsic factor
honey crusted lesions common around nose/lips
myelinates multiple CNS axons
What artery causes locked in syndrome
parietal cells
28. Von Hippel Lindau
MPTP exposure causes depletion of what NT?
brain tumor with foamy cells and high vascularity
copper - arsenic - gold antidote
hemangioblastomas of retina/cerebellum/medulla
29. Achondroplasia
catalase positive coagulase negative
Schiller Duval bodies
What hormones share a common alpha subunit
FGFR3 mutation
30. Pacinian
most common breast cancer
D cells
resembles an onion in cross section
FGFR3 mutation
31. SCID
astrocytes
spike and dome on microscope
child with eczema - coarse facial features - cold abscesses
preeclampsia
32. Kawasaki
order of nerve blockade
GM2 ganglioside accumulation
t - PA - streptokinase antidote
vasculitis of infants and children - involving coronary arteries
33. Bromocriptine
resembles an onion in cross section
best effect on HDL
what inhibits prolactin secretion
GABA - glutamine
34. Rheumatic fever
intranuclear inclusions seen in herpes simplex encephalitis
Aschoff bodies
lead antidote
tumor composed of cytotrophoblasts and syncytiotrophoblasts
35. Primary hyperaldosteronism (HTN - hypokalemia - metabolic alkalosis)
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36. Inhibits osteoclastic activity
increased MCHC and hemolytic anemia
21 hydroxylase deficiency
neutrophils fail to respond to chemotaxic stimuli
Bisphosphonates MofA
37. Dobutamine
macrolides use (PUS)
partial mole components
antibiotic with SE of eosinophilia
first line for cardiogenic shock
38. Endometrial glands inside myometrium
spike and dome on microscope
mitral valve prolapse - liver diseae - berry aneurysm
adenomyosis
dose response curve change with competitive antagonist
39. Autosomal dominant
adenomyosis
inheritance pattern for all MENs
eczema/recurrent infections/thrombocytopenia
cause of LH surge
40. Closes K+ channel on B cells causing depolarization and thus calcium influx which causes insulin release
cancer associated with Hashimoto's thyroiditis
most common breast tumor in women under 25
sulfonylureas MofA
corneal clouding & MR
41. Ach
oligohydramnios
failure of endodermal development
GM2 ganglioside accumulation
basal nucleus of Meynert
42. Motor
UMN signs
child with partial albinism - peripherial neuropathy - recurrent infections
VA/VL
anti - platelet antibodies
43. Chronic gout. inhibits reabsorbtion of uric acid in PCT
probenecid
dorsal motor nucleus
brain tumor a/w von hipple - linadu syndrome
shown to slow progression of diabetic neuropathy
44. Oculomotor
which nerve lifts the eyelid?
cause of high pH vaginal discharge
leydig cell tumor
child with partial albinism - peripherial neuropathy - recurrent infections
45. Dissociative
looks like fried eggs under histologic staining
most common gyno malignancy
may lead to multiple personalities
thyroid cancer associtated with RET oncogene
46. Chediak - Higashi
child with partial albinism - peripherial neuropathy - recurrent infections
drug that blocks purine synthesis and is metabolized by xanthine oxidase
hemangioblastomas of retina/cerebellum/medulla
alpha galacosidase A
47. Most common type of thyroid cancer
papillary thyroid cancer
beta glucocerebrosidase
mitral valve prolapse - liver diseae - berry aneurysm
preeclampsia
48. Gauchers
which nerve lifts the eyelid?
blood supply for thalamus
most common lysosomal storage disease
hallmark sign of COPD
49. Depolymerizes microtubules - impairing leukocyte chemotaxis and degranulation
opioid withdrawal
VA/VL
colchicine
follicular
50. Small diameter > large diameter; myelinated > unmyelinated
Lewy bodies composition
dose response curve with noncompetitive antagonist
order of nerve blockade
3 tumors of MEN 2b