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USMLE Pathophys

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Homocystienuria - Marfans
most common first line agent for septic shock
what nerve innervates the muscles of mastication?
3 tumors of MEN 2b
subluxation of lens

2. Normal or candida
What artery causes locked in syndrome
D cells
infliximab
cause of low pH vaginal discharge

3. Motor
heparin antidote
cause of malignant hyperthermia
what nerve innervates the muscles of mastication?
VA/VL

4. Tay Sachs
cause of malignant hyperthermia
astrocytes
floppy mitral valve dissecting aortic aneurysm - berry aneurysm
GM2 ganglioside accumulation

5. Primary biliary cirrhosis
most common lysosomal storage disease
what nerve innervates the muscles of mastication?
anti - mitochondrial antibodies
What anti - hypertensive drug has the side effect of first dose orthostatic hypotension

6. Tay SaX
contains ovarian vessels
SE: elevated LFTS - myositis
heXosaminidase
myelinates multiple CNS axons

7. Gauchers
D cells
S cells
crinkled paper cytoplasm
etanercept

8. NE
What thyroid pathology has an extremely tender thyroid gland
locus ceruleus
What artery causes locked in syndrome
thymidylate synthase

9. Inhibits platelet aggregation - promotes vasodilation and decreases uterine tone
pseudopalisading necrosis
alpha 1 anti - trypsin
17 alpha hydroxylase deficiency
PGI2 (prostacyclin))

10. Weakness - atrophy - fasiculations - decreased reflexes & tone
LMN signs
ventral posterior nucleus - medial part
pigmented iris hamartomas - neural tumors
Yolk sac tumor produces...

11. Staph epidermidis - staph sapro
cause of LH surge
intranuclear inclusions seen in herpes simplex encephalitis
most common breast cancer
catalase positive coagulase negative

12. Medulla
Where does the dorsal column decussate?
mildly decreased UDPGT
PTU
brain tumor with perivascular pseudorosettes

13. Criglar Najar
myelinates multiple CNS axons
Galactocerebrosidase deficiency
polyhydramnios
absent UTPGT

14. Gonorrhea
anti - epithelial antibodies
thayer martin media
tram - track on microscope
currant jelly stool

15. Hemangioblastoma
brain tumor a/w von hipple - linadu syndrome
found in hairless skin
raphe nucleus
Where does the spinothalamic decussate?

16. Niacins
best effect on HDL
sumatriptan
kawasaki
locus ceruleus

17. Benign - contains Reinke crystals - usually androgen producing
strawberry tongue
probenecid
leydig cell tumor
P450 inducers

18. Chloroquine and primaquine
3 tumors of MEN 1
what meds treat malaria
first line for cardiogenic shock
pacinian

19. Hemolysis - elevated LFTs - Low Platelets
placenta previa
HELLP syndrome
ventral posterior nucleus - lateral part
H. flu

20. PPAR- gamma receptor agonist - which causes improved target cell response to insulin
what checkpoint is p53 involved with?
TZD (glitazones) MofA
Shigella
propylthiouracil side effects

21. Anti - TNF antibody - use for RA but watch out for latent TB!
protease inhibitors MofA
infliximab
branching rods on oral infection
polyhydramnios

22. Penicillamine
cause of LH surge
lewy body composition
plenta accreta
copper - arsenic - gold antidote

23. Motor innervation of pharynx - larynx and upper esophagus
papillary thyroid cancer
ambiguous nucleus
SICK PEG
myelinates on PNS

24. Trichomonas or bacterial vaginosis
cause of high pH vaginal discharge
UMN signs
looks like fried eggs under histologic staining
whats the V/Q at the base of the lung

25. Membranoproliferative GN
tram - track on microscope
D cells
S cells
I cells

26. Ret
dorsal motor nucleus
Galactocerebrosidase deficiency
form multinucleated giant cells in the CNS when infected with HIV
What oncogene is a/w MEN 2a/b

27. Choriocarcinoma
oligodendrioglia
most common first line agent for septic shock
tumor composed of cytotrophoblasts and syncytiotrophoblasts
locus ceruleus

28. Sends autonomic fibers to heart
H. flu
dorsal motor nucleus
spike and dome on microscope
vasculitis of infants and children - involving coronary arteries

29. Decreased follicles & estrogen with increased FSH & LH
What are the hormone changes seen in menopause
cause of LH surge
optically clear nuclei (orphan annie)
eczema/recurrent infections/thrombocytopenia

30. Dantrolene (prevents release of calcium from SR of muscle)
follicular
drug induced lupus
treatment of malignant hyperthermia
lysosomal storage disease a/w renal disease

31. Cell type involved in most ovarian tumors
adenomyosis
protease inhibitors MofA
epithelial
low dose ASA effects - intermediate dose - high dose

32. ITP
most common breast mass in postmenopausal women
cancer arising from parafollicular C cells
treatment for SIADH
anti - platelet antibodies

33. Seborric keratosis
cause of malignant hyperthermia
MofA of N- aceylcysteine
protease inhibitors MofA
keratin filled cysts

34. PNH
Addison's
hemosiderinurea and thrombosis
hydatidiform mole with crazy high hCG
kluver bucy

35. Hereditary spherocytosis
corneal clouding & MR
most common breast mass in postmenopausal women
increased MCHC and hemolytic anemia
D cells

36. Yolk sac
brain tumor with fried egg appearance
blood supply for thalamus
most common testicular tumor in infants and children up to 3 years of age
astrocytes

37. Serous cystadenocarcinoma
cause of LH surge
oligodendrioglia
ovarian tumor with psammoma bodies
cancer associated with Hashimoto's thyroiditis

38. Barbituates - carbamazapine - griseofulvin - phenytoin - quinidine - rifampin - St. John's wort
eczema/recurrent infections/thrombocytopenia
tram - track on microscope
silver stain of gram negative rods
BCG PQRS

39. Posterior communicating - posterior cerebral - anterior choroidal arteries
melanoma tumor marker
blood supply for thalamus
Galactocerebrosidase deficiency
macrolides use (PUS)

40. Premature detachment of placenta - painful bleeding in 3rd trimester
most common breast tumor in women under 25
abruptio placentae
sumatriptan
Where does the spinothalamic decussate?

41. Suspensory ligament of ovaries
copper - arsenic - gold antidote
hemosiderinurea and thrombosis
3 tumors of MEN 2b
contains ovarian vessels

42. Fibroadenoma
most common breast tumor in women under 25
Bisphosphonates MofA
subluxation of lens
form multinucleated giant cells in the CNS when infected with HIV

43. Increased acini and intralobular fibrosis
enzyme used to conjugate bilirubin
anti - platelet antibodies
sclerosing adenosis
smoking emphysema

44. Amygdala
kluver bucy
dose response curve with noncompetitive antagonist
most common testicular tumor
Aschoff bodies

45. Schwann cells
H. flu
Bisphosphonates MofA
myelinates on PNS
sulfonylureas

46. Function as bronchoconstrictors - vasoconstrictors - sm mm contraction and increased vascular permability
brain tumor with fried egg appearance
form multinucleated giant cells in the CNS when infected with HIV
LT C4 D4 E4
most common protozoal infection in US

47. Job's or LAD
midshaft break of humerus
what meds treat malaria
neutrophils fail to respond to chemotaxic stimuli
barbituates withdrawal

48. Papillary CA of thyroid - meningioma - mesothelioma - serous cystadenocarcinoma of ovary
psammoma bodies
microglia
hemosiderinurea and thrombosis
lysosomal storage disease - demyelinating disease

49. Ovarian bengin tumor...looks like bladder
branching rods on oral infection
What causes coronary vasospasm as a SE?
What artery causes locked in syndrome
brenner tumor

50. A/w esophageal/duodenal atresia and anencephaly
antibiotic with SE of eosinophilia
strawberry tongue
lysosomal storage disease a/w renal disease
polyhydramnios