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USMLE Pathophys

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Fibrates
best effect of triglycerides/VLDL
GFAP positive
epithelial
PTU

2. Bromocriptine
anti - epithelial antibodies
colchicine
what inhibits prolactin secretion
inheritance pattern for all MENs

3. Bruton's agammaglobulinemia
erythema nodosum
defective tyrosine kinase
meissners
LT C4 D4 E4

4. Anti - TNF antibody - use for RA but watch out for latent TB!
palisading nuclei - locally invasive
low dose ASA effects - intermediate dose - high dose
infliximab
myelinates multiple CNS axons

5. HTN; masculinization
11 beta hydroxylase deficiency
floppy mitral valve dissecting aortic aneurysm - berry aneurysm
gram + bacteria that requires NAD and hemin for growth
found in hairless skin

6. Niemann Pick
erythema nodosum
cancer associated with Hashimoto's thyroiditis
sphingomyelinase deficiency
mitral valve prolapse - liver diseae - berry aneurysm

7. Oculomotor
inheritance pattern for all MENs
21 hydroxylase deficiency
ventral posterior nucleus - lateral part
which nerve lifts the eyelid?

8. Aplastic anemia - rash - agranulocytosis
propylthiouracil side effects
eczema/recurrent infections/thrombocytopenia
rate limiting step in carb digestion
which nerve lifts the eyelid?

9. Granulosa cell tumor
catalase negative
shown to slow progression of diabetic neuropathy
Shigella
tumor with call - exner bodies

10. Oligosaccaride hydrolase
VA/VL
rate limiting step in carb digestion
most common breast mass in postmenopausal women
kawasaki

11. ITP
anti - platelet antibodies
hippocampus
sclerosing adenosis
G cells

12. Medulla
branching rods on oral infection
thayer martin media
Where does the lateral corticospinal decussate?
Lateral geniculate nucleus

13. Hairless skin - dynamic fine touch
meissners
sarcoma botyroides
Bisphosphonates MofA
What hormones share a common alpha subunit

14. Hemangioblastoma
brain tumor with fried egg appearance
brain tumor with foamy cells and high vascularity
lead antidote
Schiller Duval bodies

15. Protamine sulfate
first line for absence seizures
heparin antidote
MPTP exposure causes depletion of what NT?
ependymal cells

16. Kawasaki
vasculitis of infants and children - involving coronary arteries
antibody against philadelphia chromosome
MofA of N- aceylcysteine
most common breast cancer

17. Hemangioblastoma
brain tumor a/w von hipple - linadu syndrome
dose response curve with noncompetitive antagonist
first line for absence seizures
kluver bucy

18. Penicillamine
infliximab
form multinucleated giant cells in the CNS when infected with HIV
copper - arsenic - gold antidote
vasculitis of infants and children - involving coronary arteries

19. I- cell disease
HELLP syndrome
schwann cells
deficiency of mannose phosphorylation
catalase positive coagulase negative

20. PPAR- gamma receptor agonist - which causes improved target cell response to insulin
what inhibits prolactin secretion
abruptio placentae
TZD (glitazones) MofA
von Hippel Lindau disease

21. A few levels above the level of entry
cough - conjunctivitis - coryza - fever
VA/VL
etanercept
Where does the spinothalamic decussate?

22. Antibody binds to gp2b/3a - preventing aggregation
ovarian tumor with elevate hCG
looks like fried eggs under histologic staining
Abciximab
bocks PRPP synthetase to block purine synthesis

23. Cocain and sumatriptan
Galactocerebrosidase deficiency
grossly black liver
low dose ASA effects - intermediate dose - high dose
What causes coronary vasospasm as a SE?

24. Closes K+ channel on B cells causing depolarization and thus calcium influx which causes insulin release
homer wright rosettes
testicular tumor that can present with gynecomastia
sulfonylureas MofA
BCG PQRS

25. Cowdry type A inclusions
polyhydramnios
bocks PRPP synthetase to block purine synthesis
intranuclear inclusions seen in herpes simplex encephalitis
smoking emphysema

26. Panacinar
alpha 1 anti - trypsin
thayer martin media
low dose ASA effects - intermediate dose - high dose
subluxation of lens

27. Kawasaki (treat with high dose aspirin)
copper - arsenic - gold antidote
strawberry tongue
What thyroid pathology has an extremely tender thyroid gland
first line for cardiogenic shock

28. Dobutamine
first line for cardiogenic shock
antibody against philadelphia chromosome
most common protozoal infection in US
hep B seropositivity in 30% of patients

29. Meningioma
strawberry tongue
brain tumor with psammona bodies
MPTP exposure causes depletion of what NT?
Lateral geniculate nucleus

30. Estrogen
most common first line agent for septic shock
cause of LH surge
SE: elevated LFTS - myositis
psammoma bodies

31. Weakness - atrophy - fasiculations - decreased reflexes & tone
contains ovarian vessels
LMN signs
Lateral geniculate nucleus
I cells

32. Damaged in Guillian Barre
sphingomyelinase deficiency
Conn's syndrome
schwann cells
colchicine

33. Posterior communicating - posterior cerebral - anterior choroidal arteries
blood supply for thalamus
resembles an onion in cross section
probenecid
cancer arising from parafollicular C cells

34. Glucuronyl transferase
partial mole components
enzyme used to conjugate bilirubin
order of nerve blockade
gram + bacteria that requires NAD and hemin for growth

35. 2 sperm + 1 egg (fetal parts present)
partial mole components
MofA Levothyroxine
pseudopalisading necrosis
Bisphosphonates MofA

36. Serotonin
raphe nucleus
sulfonylureas
solitarius nucleus
thromboxane A2

37. Port wine stains - ipsilateral leptomeningeal angioma; can cause glaucoma - seizures - hemipareis - and MR
metformin side effect
sturge weber syndrome
Yolk sac tumor produces...
pt has extended expiratory phase

38. Memory
FGFR3 mutation
cause of high pH vaginal discharge
macrolides use (PUS)
hippocampus

39. Inhibitory in the SC
What anti - hypertensive drug has the side effect of first dose orthostatic hypotension
glycine
What are the hormone changes seen in menopause
most common breast tumor in women under 25

40. Parathyroid - pituitary - pancreatic
FGFR3 mutation
3 tumors of MEN 1
iduronidase sulfatase
melanoma tumor marker

41. Inflammatory lesions of subq fat - usually on anterior shins. a/w infections
sphingomyelinase deficiency
thayer martin media
melanoma tumor marker
erythema nodosum

42. Neurofibromatosis
leydig cell tumor
ambiguous nucleus
lisch nodules
alpha galacosidase A

43. Intrinsic factor
parietal cells
smoking emphysema
copper - arsenic - gold antidote
cause of low pH vaginal discharge

44. Polyarteritis nodosa
brain tumor with fried egg appearance
complete mole components
vasculitis a/w Hep B
sulfonylureas MofA

45. Basal cell carcinoma
palisading nuclei - locally invasive
x- linked recessive lysosomal storage diseases
thromboxane A2
brain tumor with foamy cells and high vascularity

46. Bilateral renal agenesis or posterior urethral valves in males
HELLP syndrome
What oncogene is a/w MEN 2a/b
oligohydramnios
what nerve innervates the muscles of mastication?

47. Seminoma
spike and dome on microscope
GFAP positive
heXosaminidase
most common testicular tumor

48. Lymphoma

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49. Centriacinar
smoking emphysema
most common testicular tumor
dorsal motor nucleus
dose response curve with noncompetitive antagonist

50. Sotalol - quinidine - cisapride
silver stain of gram negative rods
SE: torsades de pointes
drug that blocks purine synthesis and is metabolized by xanthine oxidase
child with eczema - coarse facial features - cold abscesses