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USMLE Pathophys

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Niacin
Conn's syndrome
SE: facial flushing
psammoma bodies
most common first line agent for septic shock

2. 5- fluorouracil
G cells
hep B seropositivity in 30% of patients
What hormones share a common alpha subunit
thymidylate synthase

3. Fabrys
tumor with call - exner bodies
antibody against philadelphia chromosome
honey crusted lesions common around nose/lips
alpha galacosidase A

4. Actinomyces
psammoma bodies
infliximab
rabies
branching rods on oral infection

5. ADPKD
spike and dome on microscope
What causes coronary vasospasm as a SE?
mitral valve prolapse - liver diseae - berry aneurysm
myelinates on PNS

6. Oligodendrogila
kluver bucy
cells destroyed in MS
alpha L iduronidase
cancer arising from parafollicular C cells

7. Causes vasoconstriction (use for acute migraines)
copper - arsenic - gold antidote
11 beta hydroxylase deficiency
epithelial
sumatriptan

8. Body sensation
MPTP exposure causes depletion of what NT?
papillary thyroid cancer
ventral posterior nucleus - lateral part
ovarian tumor that resembles bladder epithelium

9. Neutrophil chemotactic agent 'neutrophils arrive B4 others'
may lead to multiple personalities
LTB4
subluxation of lens
defective tyrosine kinase

10. D cells of pancreas and gut
PGI2 (prostacyclin))
preeclampsia
what cells secrete somatostatin
macrolides use (PUS)

11. Yolk sac tumor
Schiller Duval bodies
17 alpha hydroxylase deficiency
which nerve lifts the eyelid?
pigmented iris hamartomas - neural tumors

12. Macconkey's agar
brain tumor a/w von hipple - linadu syndrome
ventral posterior nucleus - lateral part
what cells secrete somatostatin
Shigella

13. Gilberts
mildly decreased UDPGT
x- linked recessive lysosomal storage diseases
treatment of malignant hyperthermia
pacinian

14. Lymphoma

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15. Hurlers - Hunters
dermatin sulfate accumulation
3 tumors of MEN 1
cause of malignant hyperthermia
looks like fried eggs under histologic staining

16. Dubin Johnson
grossly black liver
anti - epithelial antibodies
basal nucleus of Meynert
ependymal cells

17. Sotalol - quinidine - cisapride
myelinates on PNS
medial geniculate nucleus
Abciximab
SE: torsades de pointes

18. Krabbe's
Galactocerebrosidase deficiency
bocks PRPP synthetase to block purine synthesis
pt has extended expiratory phase
D cells

19. H. Influenza
pacinian
gram + bacteria that requires NAD and hemin for growth
homer wright rosettes
3 tumors of MEN 2b

20. Visceral sensory
thyroid cancer associtated with RET oncogene
hep B seropositivity in 30% of patients
solitarius nucleus
chief cells

21. CCK
opioid withdrawal
most common breast mass in pre - menopausal women
I cells
hemangioblastomas of retina/cerebellum/medulla

22. Intussception
currant jelly stool
complete mole components
heparin antidote
P450 Inhibitors

23. TSH - LH - FSH - hCG
MofA of N- aceylcysteine
Galactocerebrosidase deficiency
What hormones share a common alpha subunit
What artery causes locked in syndrome

24. Legionella
lisch nodules
silver stain of gram negative rods
solitarius nucleus
hydrocele

25. Decreased potency - increased Km
hydatidiform mole with crazy high hCG
dose response curve change with competitive antagonist
sulfonylureas MofA
thyroid cancer associtated with RET oncogene

26. Schwann cells
thayer martin media
myelinates on PNS
heparin antidote
thyroid cancer associtated with RET oncogene

27. Chocolate agar
brenner tumor
H. flu
SE: torsades de pointes
propylthiouracil side effects

28. Ach
defective tyrosine kinase
basal nucleus of Meynert
sumatriptan
MPTP exposure causes depletion of what NT?

29. Hemangioblastoma
chief cells
rabies
brain tumor with foamy cells and high vascularity
homer wright rosettes

30. Gauchers
I cells
MPTP exposure causes depletion of what NT?
GM2 ganglioside accumulation
most common lysosomal storage disease

31. Glutamate
precursor to GABA
most common breast tumor in women under 25
nucleoside reverse transcriptase inhibitors
subluxation of lens

32. Medulla
increased MCHC and hemolytic anemia
17 alpha hydroxylase deficiency
Where does the lateral corticospinal decussate?
cells destroyed in Guillain Barre

33. Somatostatin
D cells
child with eczema - coarse facial features - cold abscesses
which nerve lifts the eyelid?
polyhydramnios

34. Hurlers
kawasaki
increased MCHC and hemolytic anemia
corneal clouding & MR
PTU

35. Inhibits osteoclastic activity
thymidylate synthase
dose response curve with noncompetitive antagonist
Bisphosphonates MofA
dorsal motor nucleus

36. Flumazenil
benzos antidote
astrocytes
what meds treat malaria
crinkled paper cytoplasm

37. Centriacinar
subluxation of lens
smoking emphysema
plenta accreta
cancer arising from parafollicular C cells

38. Attachment of placenta to lower uterine segment
placenta previa
sulfonylureas
polyhydramnios
iduronidase sulfatase

39. Ethosuximide
TZD (glitazones) MofA
astrocytes
anti - epithelial antibodies
first line for absence seizures

40. Prazosin
GM2 ganglioside accumulation
most common breast mass in pre - menopausal women
What anti - hypertensive drug has the side effect of first dose orthostatic hypotension
rabies

41. Chloroquine and primaquine
currant jelly stool
S cells
what meds treat malaria
cancer arising from parafollicular C cells

42. Panacinar
sphingomyelinase deficiency
meissners
alpha 1 anti - trypsin
hemosiderinurea + thrombosis

43. Polyarteritis nodosa
vasculitis a/w Hep B
catalase negative
microglia
partial mole components

44. Niacins
chief cells
most common breast mass in postmenopausal women
pacinian
best effect on HDL

45. Amygdala
iduronidase sulfatase
astrocytes
pt has extended expiratory phase
kluver bucy

46. Posterior communicating - posterior cerebral - anterior choroidal arteries
vasculitis a/w Hep B
blood supply for thalamus
mildly decreased UDPGT
spike and dome on microscope

47. Basilar
propylthiouracil side effects
What artery causes locked in syndrome
opioids antidote
basal nucleus of Meynert

48. ACE inhibitors
protease inhibitors MofA
5 alpha reductase deficiency
x- linked recessive lysosomal storage diseases
shown to slow progression of diabetic neuropathy

49. Subacute (De Quervain's) thyroiditis
Where does the lateral corticospinal decussate?
lysosomal storage disease a/w renal disease
What thyroid pathology has an extremely tender thyroid gland
3 tumors of MEN 1

50. Cocain and sumatriptan
ambiguous nucleus
What causes coronary vasospasm as a SE?
midshaft break of humerus
branching rods on oral infection