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USMLE Pathophys

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Antibody binds to gp2b/3a - preventing aggregation
inheritance pattern for all MENs
melanoma tumor marker
ovarian tumor with elevate hCG
Abciximab

2. Masculinization - hypovolemic shock
brain tumor with foamy cells and high vascularity
basal nucleus of Meynert
branching rods on oral infection
21 hydroxylase deficiency

3. Chocolate agar
H. flu
vasculitis of infants and children - involving coronary arteries
most common lysosomal storage disease
Galactocerebrosidase deficiency

4. Penicillamine
brain tumor with psammona bodies
copper - arsenic - gold antidote
polyhydramnios
sulfonylureas side effect

5. BCG PQRS
MofA of N- aceylcysteine
granulosa cell tumor secretes what?
pigmented iris hamartomas - neural tumors
P450 inducers

6. Normal or candida
thymidylate synthase
cancer arising from parafollicular C cells
branching rods on oral infection
cause of low pH vaginal discharge

7. Alpha feto protein
mildly decreased UDPGT
cough - conjunctivitis - coryza - fever
psammoma bodies
Yolk sac tumor produces...

8. Complete
astrocytes
child with partial albinism - peripherial neuropathy - recurrent infections
solitarius nucleus
hydatidiform mole with crazy high hCG

9. Medullary thyroid - pheochromocytoma - oral/intestinal ganglionueromatosis
subluxation of lens
pseudopalisading necrosis
3 tumors of MEN 2b
brain tumor with foamy cells and high vascularity

10. Fabry's & Hunters
astrocytes
chief cells
pigmented iris hamartomas - neural tumors
x- linked recessive lysosomal storage diseases

11. Dopamine
found in hairless skin
MPTP exposure causes depletion of what NT?
cells destroyed in MS
hemosiderinurea + thrombosis

12. Gonorrhea
hep B seropositivity in 30% of patients
thayer martin media
hemangioblastomas of retina/cerebellum/medulla
lisch nodules

13. Papillary
thyroid cancer associtated with RET oncogene
gram + bacteria that requires NAD and hemin for growth
LMN signs
I cells

14. Superchiasmic nucleus
form multinucleated giant cells in the CNS when infected with HIV
VA/VL
what cells secrete somatostatin
master clock for circadian rhythms

15. Somatostatin
Abciximab
D cells
ependymal cells
SE: torsades de pointes

16. 2 sperm + 1 egg (fetal parts present)
copper - arsenic - gold antidote
GM2 ganglioside accumulation
sphingomyelinase deficiency
partial mole components

17. H. Influenza
brain tumor with perivascular pseudorosettes
hallmark sign of COPD
gram + bacteria that requires NAD and hemin for growth
cause of low pH vaginal discharge

18. Polyarteritis nodosa
hep B seropositivity in 30% of patients
sulfonylureas
sclerosing adenosis
smoking emphysema

19. Job's or LAD
neutrophils fail to respond to chemotaxic stimuli
dose response curve with noncompetitive antagonist
most common arrthymia
SE: facial flushing

20. Anxiety - insomnia - sweating - dilated pupils - piloerection - rhinorrhea
11 beta hydroxylase deficiency
partial mole components
absent UTPGT
opioid withdrawal

21. Homocystienuria - Marfans
hippocampus
subluxation of lens
BCG PQRS
lewy body composition

22. Basal cell carcinoma
preeclampsia
palisading nuclei - locally invasive
myelinates multiple CNS axons
anti - epithelial antibodies

23. Subacute (De Quervain's) thyroiditis
whats the V/Q at the base of the lung
What thyroid pathology has an extremely tender thyroid gland
crinkled paper cytoplasm
P450 Inhibitors

24. Decreased potency - increased Km
dose response curve change with competitive antagonist
copper - arsenic - gold antidote
placenta previa
absent UTPGT

25. G1/S & G2/M
what checkpoint is p53 involved with?
astrocytes
cough - conjunctivitis - coryza - fever
I cells

26. 2 sperm + empty egg (no fetal parts)
complete mole components
antibody against philadelphia chromosome
pacinian
paraventricular nucleus of hypothalamus

27. Alpha synuclein
branching rods on oral infection
Yolk sac tumor produces...
Lewy bodies composition
meissners

28. SCID
child with eczema - coarse facial features - cold abscesses
BCG PQRS
Aschoff bodies
brain tumor with perivascular pseudorosettes

29. PPAR- gamma receptor agonist - which causes improved target cell response to insulin
most common arrthymia
TZD (glitazones) MofA
cause of high pH vaginal discharge
defective tyrosine kinase

30. Membranoproliferative GN
alpha L iduronidase
kluver bucy
tram - track on microscope
most common testicular tumor in infants and children up to 3 years of age

31. Niacins
best effect on HDL
catalase negative
glycine
alpha galacosidase A

32. Gauchers
protease inhibitors MofA
hallmark sign of COPD
beta glucocerebrosidase
Shigella

33. Yolk sac
most common arrthymia
most common testicular tumor in infants and children up to 3 years of age
neutrophils fail to respond to chemotaxic stimuli
enzyme used to conjugate bilirubin

34. Legionella
silver stain of gram negative rods
Yolk sac tumor produces...
melanoma tumor marker
fusion inhibitors

35. Babinski - weakness - increased reflexes & tone - spastic paralysis
UMN signs
GABA - glutamine
psammoma bodies
lysosomal storage disease a/w renal disease

36. Chronic gout. inhibits reabsorbtion of uric acid in PCT
cause of LH surge
lewy body composition
probenecid
treatment for SIADH

37. Hunters
iduronidase sulfatase
copper - arsenic - gold antidote
contains ovarian vessels
anti - epithelial antibodies

38. Astrocytoma & glioblastoma multiforme
melanoma tumor marker
colchicine
P450 Inhibitors
GFAP positive

39. Tay SaX
mildly decreased UDPGT
VA/VL
heXosaminidase
UMN signs

40. Alpha synuclein
lewy body composition
mitral valve prolapse - liver diseae - berry aneurysm
what nerve innervates the muscles of mastication?
copper - arsenic - gold antidote

41. 0.6
whats the V/Q at the base of the lung
granulosa cell tumor secretes what?
precursor to GABA
Abciximab

42. Niacin
Shigella
SE: facial flushing
TZD (glitazones) MofA
enzyme used to conjugate bilirubin

43. Metachromatic leukodystrophy
VA/VL
follicular
cause of low pH vaginal discharge
lysosomal storage disease - demyelinating disease

44. Cant convert testosterone to DHT - ambiguous genitalia until puberty then penis at 12
which nerve lifts the eyelid?
diphtheria treatment
5 alpha reductase deficiency
gram + bacteria that requires NAD and hemin for growth

45. Prevents incorporation into host DNA
nucleoside reverse transcriptase inhibitors
ventral posterior nucleus - medial part
neutrophils fail to respond to chemotaxic stimuli
cause of LH surge

46. Flumazenil
most common breast mass in pre - menopausal women
benzos antidote
Aschoff bodies
cancer associated with Hashimoto's thyroiditis

47. Small diameter > large diameter; myelinated > unmyelinated
most common gyno malignancy
order of nerve blockade
dorsal motor nucleus
LTB4

48. Negri bodies
shown to slow progression of diabetic neuropathy
rabies
catalase positive coagulase negative
opioids antidote

49. Decreased efficacy - decreased Vmax
MPTP exposure causes depletion of what NT?
infliximab
copper - arsenic - gold antidote
dose response curve with noncompetitive antagonist

50. Hurlers - Hunters
UMN signs
sulfonylureas MofA
dermatin sulfate accumulation
locus ceruleus