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USMLE Pathophys

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Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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1. Cause release of preformed insulin
sulfonylureas
21 hydroxylase deficiency
propylthiouracil side effects
Galactocerebrosidase deficiency

2. Protamine sulfate
meissners
opioid withdrawal
most common breast mass in pre - menopausal women
heparin antidote

3. Inflammatory lesions of subq fat - usually on anterior shins. a/w infections
inheritance pattern for all MENs
most common first line agent for septic shock
erythema nodosum
epithelial

4. Hurlers - Hunters
Schiller Duval bodies
solitarius nucleus
beta glucocerebrosidase
dermatin sulfate accumulation

5. Increased acini and intralobular fibrosis
sclerosing adenosis
erythema nodosum
P450 Inhibitors
gram + bacteria that requires NAD and hemin for growth

6. Clopidogrel - ticoplidine
Addison's
H. flu
most common breast mass in pre - menopausal women
blocks ADP receptors to inhibit platelet aggregation

7. Autosomal dominant
what checkpoint is p53 involved with?
blood supply for thalamus
inheritance pattern for all MENs
best effect of triglycerides/VLDL

8. Impetigo
contains ovarian vessels
honey crusted lesions common around nose/lips
heparin antidote
silver stain of gram negative rods

9. Primary hyperaldosteronism (HTN - hypokalemia - metabolic alkalosis)

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10. Legionella
blocks ADP receptors to inhibit platelet aggregation
P450 Inhibitors
eczema/recurrent infections/thrombocytopenia
silver stain of gram negative rods

11. Rheumatic fever
infliximab
Aschoff bodies
locus ceruleus
GABA - glutamine

12. Bilateral renal agenesis or posterior urethral valves in males
oligohydramnios
leydig cell tumor
anti - mitochondrial antibodies
beta glucocerebrosidase

13. Makes oxytocin
cancer associated with Hashimoto's thyroiditis
abruptio placentae
sulfonylureas MofA
paraventricular nucleus of hypothalamus

14. Inhibitory in the SC
ovarian tumor that resembles bladder epithelium
supraoptic nucleus of hypothalamus
anti - mitochondrial antibodies
glycine

15. ACE inhibitors
shown to slow progression of diabetic neuropathy
SE: elevated LFTS - myositis
most common primary cardiac tumor in kiddos
mildly decreased UDPGT

16. Deficiency of aldosterone and cortisol

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17. Closes K+ channel on B cells causing depolarization and thus calcium influx which causes insulin release
myelinates multiple CNS axons
papillary thyroid cancer
rate limiting step in carb digestion
sulfonylureas MofA

18. Incomplete fusion of processus vaginalis
brain tumor with foamy cells and high vascularity
hydrocele
What hormones share a common alpha subunit
basal nucleus of Meynert

19. Subacute (De Quervain's) thyroiditis
heXosaminidase
What thyroid pathology has an extremely tender thyroid gland
lead antidote
palisading nuclei - locally invasive

20. Masculinization - hypovolemic shock
LTB4
21 hydroxylase deficiency
macrolides use (PUS)
corneal clouding & MR

21. Macconkey's agar
polyhydramnios
Shigella
honey crusted lesions common around nose/lips
antibody against philadelphia chromosome

22. Suspensory ligament of ovaries
P450 Inhibitors
contains ovarian vessels
supraoptic nucleus of hypothalamus
most common protozoal infection in US

23. Medulla
Where does the lateral corticospinal decussate?
UMN signs
partial mole components
sulfonylureas MofA

24. Hemolysis - elevated LFTs - Low Platelets
eczema/recurrent infections/thrombocytopenia
HELLP syndrome
diphtheria treatment
Where does the lateral corticospinal decussate?

25. Prevents incorporation into host DNA
anti - platelet antibodies
erythema nodosum
most common breast cancer
nucleoside reverse transcriptase inhibitors

26. Sulfonamides - Isonizid - Cimetidine - Ketoconazole - Erythromyicn - grapefruit juice - protease inhibitors
etanercept
SICK PEG
plenta accreta
What are the hormone changes seen in menopause

27. Oculomotor
which nerve lifts the eyelid?
locus ceruleus
opioid withdrawal
palisading nuclei - locally invasive

28. I- cell disease
ambiguous nucleus
UMN signs
dose response curve change with competitive antagonist
deficiency of mannose phosphorylation

29. Astrocytoma & glioblastoma multiforme
cause of high pH vaginal discharge
diphtheria treatment
beta glucocerebrosidase
GFAP positive

30. Polyarteritis nodosa
MofA Levothyroxine
ovarian tumor with elevate hCG
contains ovarian vessels
vasculitis a/w Hep B

31. Dopamine
anti - platelet antibodies
sulfonylureas side effect
MPTP exposure causes depletion of what NT?
astrocytes

32. CCK
treatment for SIADH
corneal clouding & MR
absent UTPGT
I cells

33. Fibrates
Galactocerebrosidase deficiency
epithelial
best effect of triglycerides/VLDL
myelinates on PNS

34. Trichomonas - Giardia
most common protozoal infection in US
What thyroid pathology has an extremely tender thyroid gland
TZD (glitazones) MofA
corneal clouding & MR

35. Gauchers
best effect of triglycerides/VLDL
optically clear nuclei (orphan annie)
most common lysosomal storage disease
Shigella

36. A few levels above the level of entry
myelinates multiple CNS axons
lysosomal storage disease a/w renal disease
Where does the spinothalamic decussate?
MofA Levothyroxine

37. Estrogen (causes precocious puberty)
21 hydroxylase deficiency
follicular
granulosa cell tumor secretes what?
supraoptic nucleus of hypothalamus

38. HTN; XY will be a girl - XX will lack secondary sex char.
antibiotic with SE of eosinophilia
t - PA - streptokinase antidote
17 alpha hydroxylase deficiency
eczema/recurrent infections/thrombocytopenia

39. PNH
deficiency of mannose phosphorylation
benzos antidote
opioid withdrawal
hemosiderinurea and thrombosis

40. Choriocarcinoma
branching rods on oral infection
tumor composed of cytotrophoblasts and syncytiotrophoblasts
order of nerve blockade
what inhibits prolactin secretion

41. Decreased FEV/FVC ratio
beta glucocerebrosidase
GM2 ganglioside accumulation
hallmark sign of COPD
failure of endodermal development

42. TNF receptor
metformin side effect
brain tumor with perivascular pseudorosettes
ventral posterior nucleus - medial part
etanercept

43. Inner lining of ventricles - make CSF - originate from neuroectoderm
ependymal cells
basal nucleus of Meynert
lysosomal storage disease - demyelinating disease
pigmented iris hamartomas - neural tumors

44. Actinomyces
mildly decreased UDPGT
branching rods on oral infection
hydatidiform mole with crazy high hCG
brain tumor with foamy cells and high vascularity

45. Inhibits osteoclastic activity
Bisphosphonates MofA
lisch nodules
opioid withdrawal
most common breast mass in postmenopausal women

46. Krabbe's
Galactocerebrosidase deficiency
erythema nodosum
most common protozoal infection in US
sulfonylureas MofA

47. Support - repair - potassium metabolism - remove excess NT - maintain BBB - marker is GFAP
palisading nuclei - locally invasive
astrocytes
branching rods on oral infection
which nerve lifts the eyelid?

48. Seminoma
brenner tumor
corneal clouding & MR
brain tumor with perivascular pseudorosettes
most common testicular tumor

49. Dubin Johnson
grossly black liver
hippocampus
oligohydramnios
thymidylate synthase

50. Macrophages of the CNS
ventral posterior nucleus - lateral part
most common first line agent for septic shock
shown to slow progression of diabetic neuropathy
microglia

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USMLE Pathophys

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