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USMLE Pathophys

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. G1/S & G2/M
benzos antidote
iduronidase sulfatase
pt has extended expiratory phase
what checkpoint is p53 involved with?

2. Homocystienuria - Marfans
found in hairless skin
mitral valve prolapse - liver diseae - berry aneurysm
subluxation of lens
whats the V/Q at the apex of the lung

3. BCG PQRS
pacinian
palisading nuclei - locally invasive
form multinucleated giant cells in the CNS when infected with HIV
P450 inducers

4. Increased acini and intralobular fibrosis
nucleoside reverse transcriptase inhibitors
homer wright rosettes
D cells
sclerosing adenosis

5. Benign - contains Reinke crystals - usually androgen producing
polyhydramnios
contains ovarian vessels
glycine
leydig cell tumor

6. Vaginal carcinoma: spindle shaped tumor cells that are desmin positive
sarcoma botyroides
low dose ASA effects - intermediate dose - high dose
looks like fried eggs under histologic staining
3 tumors of MEN 2a

7. Trichomonas - Giardia
subluxation of lens
most common protozoal infection in US
pigmented iris hamartomas - neural tumors
gram + bacteria that requires NAD and hemin for growth

8. Basilar
ovarian tumor that resembles bladder epithelium
What artery causes locked in syndrome
SICK PEG
metformin side effect

9. Chronic gout. inhibits reabsorbtion of uric acid in PCT
failure of endodermal development
probenecid
thayer martin media
antibiotic with SE of eosinophilia

10. Intussception
bocks PRPP synthetase to block purine synthesis
brenner tumor
rate limiting step in carb digestion
currant jelly stool

11. Macconkey's agar
Shigella
failure of endodermal development
may lead to multiple personalities
opioids antidote

12. Decreased efficacy - decreased Vmax
colchicine
pt has extended expiratory phase
dose response curve with noncompetitive antagonist
protease inhibitors MofA

13. Glioblastoma multiforme
cause of increased myometrial excitability
most common gyno malignancy
pseudopalisading necrosis
brain tumor with fried egg appearance

14. Incomplete fusion of processus vaginalis
hydrocele
cause of low pH vaginal discharge
brain tumor with foamy cells and high vascularity
thymidylate synthase

15. Naloxone/naltrexone
smoking emphysema
beta glucocerebrosidase
cells destroyed in MS
opioids antidote

16. Measles
increased MCHC and hemolytic anemia
neutrophils fail to respond to chemotaxic stimuli
cough - conjunctivitis - coryza - fever
deficiency of mannose phosphorylation

17. 5- fluorouracil
sumatriptan
what checkpoint is p53 involved with?
thymidylate synthase
whats the V/Q at the base of the lung

18. Dobutamine
drug that blocks purine synthesis and is metabolized by xanthine oxidase
whats the V/Q at the apex of the lung
first line for cardiogenic shock
LTB4

19. 3
whats the V/Q at the apex of the lung
D cells
lewy body composition
plenta accreta

20. 6- MP
cause of increased myometrial excitability
sarcoma botyroides
drug that blocks purine synthesis and is metabolized by xanthine oxidase
myelinates on PNS

21. D cells of pancreas and gut
cough - conjunctivitis - coryza - fever
what cells secrete somatostatin
tram - track on microscope
keratin filled cysts

22. B. fragilis
Shigella
form multinucleated giant cells in the CNS when infected with HIV
most common bacteria in GI tract
what checkpoint is p53 involved with?

23. Invasive ductal CA
dose response curve with noncompetitive antagonist
dermatin sulfate accumulation
most common breast mass in postmenopausal women
palisading nuclei - locally invasive

24. Serotonin
raphe nucleus
ventral posterior nucleus - lateral part
LTB4
protease inhibitors MofA

25. Makes ADH
MofA Levothyroxine
brain tumor a/w von hipple - linadu syndrome
homer wright rosettes
supraoptic nucleus of hypothalamus

26. Visual (Lateral for Light)
pigmented iris hamartomas - neural tumors
Lateral geniculate nucleus
oligodendrioglia
brenner tumor

27. Norepinephrine
cause of high pH vaginal discharge
locus ceruleus
alpha galacosidase A
first line for cardiogenic shock

28. Motor innervation of pharynx - larynx and upper esophagus
resembles an onion in cross section
What anti - hypertensive drug has the side effect of first dose orthostatic hypotension
UMN signs
ambiguous nucleus

29. Vibration - pressure
may lead to multiple personalities
sulfonylureas side effect
pacinian
probenecid

30. Damaged in multiple sclerosis
brain tumor with foamy cells and high vascularity
sturge weber syndrome
oligodendrioglia
myelinates on PNS

31. Meningioma
brain tumor with psammona bodies
SE: torsades de pointes
brenner tumor
most common arrthymia

32. PNH
most common primary cardiac tumor in kiddos
hallmark sign of COPD
hemosiderinurea and thrombosis
kluver bucy

33. Ovarian bengin tumor...looks like bladder
spike and dome on microscope
most common breast mass in pre - menopausal women
brenner tumor
brain tumor with psammona bodies

34. Membranous GN
ambiguous nucleus
spike and dome on microscope
child with eczema - coarse facial features - cold abscesses
resembles an onion in cross section

35. ACE inhibitors
drug that blocks purine synthesis and is metabolized by xanthine oxidase
found in hairless skin
macrolides use (PUS)
shown to slow progression of diabetic neuropathy

36. Ethosuximide
astrocytes
brain tumor with fried egg appearance
first line for absence seizures
granulosa cell tumor secretes what?

37. Dimercaprol
lead antidote
thromboxane A2
medial geniculate nucleus
S cells

38. Granulosa cell tumor
sumatriptan
von Hippel Lindau disease
Where does the dorsal column decussate?
tumor with call - exner bodies

39. Hemangioblastoma
GABA - glutamine
What anti - hypertensive drug has the side effect of first dose orthostatic hypotension
brain tumor with foamy cells and high vascularity
alpha L iduronidase

40. Medulloblastoma
chief cells
low dose ASA effects - intermediate dose - high dose
homer wright rosettes
MPTP exposure causes depletion of what NT?

41. Glucuronyl transferase
tram - track on microscope
cells destroyed in MS
diphtheria treatment
enzyme used to conjugate bilirubin

42. Rheumatic fever
strawberry tongue
Aschoff bodies
LTB4
placenta previa

43. Deficiency of aldosterone and cortisol

44. TSH - LH - FSH - hCG
P450 Inhibitors
anti - epithelial antibodies
master clock for circadian rhythms
What hormones share a common alpha subunit

45. Amygdala
kluver bucy
melanoma tumor marker
testicular tumor that can present with gynecomastia
child with partial albinism - peripherial neuropathy - recurrent infections

46. Krabbe's
alpha 1 anti - trypsin
Galactocerebrosidase deficiency
anti - platelet antibodies
child with partial albinism - peripherial neuropathy - recurrent infections

47. Hereditary spherocytosis
alpha L iduronidase
increased MCHC and hemolytic anemia
alpha galacosidase A
cells destroyed in MS

48. Trichomonas or bacterial vaginosis
resembles an onion in cross section
cause of high pH vaginal discharge
pt has extended expiratory phase
gram + bacteria that requires NAD and hemin for growth

49. Kawasaki
medial geniculate nucleus
ovarian tumor with psammoma bodies
vasculitis of infants and children - involving coronary arteries
macrolides use (PUS)

50. Oligodendrioma
brain tumor with fried egg appearance
MofA of N- aceylcysteine
dorsal motor nucleus
supraoptic nucleus of hypothalamus