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USMLE Pathophys

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Oligodendrioma
pseudopalisading necrosis
cause of low pH vaginal discharge
brain tumor with fried egg appearance
what nerve innervates the muscles of mastication?

2. Decreases conversion
PTU
midshaft break of humerus
pacinian
locus ceruleus

3. Ach
tram - track on microscope
lisch nodules
basal nucleus of Meynert
colchicine

4. Port wine stains - ipsilateral leptomeningeal angioma; can cause glaucoma - seizures - hemipareis - and MR
sturge weber syndrome
5 alpha reductase deficiency
lisch nodules
honey crusted lesions common around nose/lips

5. Complete
copper - arsenic - gold antidote
first line for cardiogenic shock
smoking emphysema
hydatidiform mole with crazy high hCG

6. Auditory (Medial for Music)
catalase negative
anti - platelet antibodies
what checkpoint is p53 involved with?
medial geniculate nucleus

7. Von Hippel Lindau
Where does the spinothalamic decussate?
MofA of N- aceylcysteine
corneal clouding & MR
hemangioblastomas of retina/cerebellum/medulla

8. Depolymerizes microtubules - impairing leukocyte chemotaxis and degranulation
shown to slow progression of diabetic neuropathy
colchicine
hemosiderinurea + thrombosis
precursor to GABA

9. 2 sperm + empty egg (no fetal parts)
blocks ADP receptors to inhibit platelet aggregation
neutrophils fail to respond to chemotaxic stimuli
hydatidiform mole with crazy high hCG
complete mole components

10. Gauchers
P450 inducers
most common lysosomal storage disease
schwann cells
deficiency of mannose phosphorylation

11. Anxiety - insomnia - sweating - dilated pupils - piloerection - rhinorrhea
contains ovarian vessels
opioid withdrawal
honey crusted lesions common around nose/lips
anti - platelet antibodies

12. Bilateral renal agenesis or posterior urethral valves in males
oligohydramnios
cancer arising from parafollicular C cells
child with eczema - coarse facial features - cold abscesses
21 hydroxylase deficiency

13. S-100
SE: elevated LFTS - myositis
melanoma tumor marker
testicular tumor that can present with gynecomastia
cells destroyed in MS

14. Fibrocystic
What thyroid pathology has an extremely tender thyroid gland
most common breast mass in pre - menopausal women
metformin side effect
TZD (glitazones) MofA

15. Hurlers
most common testicular tumor in infants and children up to 3 years of age
intranuclear inclusions seen in herpes simplex encephalitis
corneal clouding & MR
pacinian

16. Marfans
hemosiderinurea and thrombosis
schwann cells
oligodendrioglia
floppy mitral valve dissecting aortic aneurysm - berry aneurysm

17. Alpha synuclein
solitarius nucleus
lewy body composition
Where does the dorsal column decussate?
vasculitis a/w Hep B

18. Alpha synuclein
contains ovarian vessels
Lewy bodies composition
precursor to GABA
colchicine

19. Sulfonamides - Isonizid - Cimetidine - Ketoconazole - Erythromyicn - grapefruit juice - protease inhibitors
meissners
anti - platelet antibodies
hippocampus
SICK PEG

20. Glutamate
precursor to GABA
cause of increased myometrial excitability
GM2 ganglioside accumulation
treatment of malignant hyperthermia

21. Medullary thyroid - pheochromocytoma - parathryoid
chromosome 4
currant jelly stool
3 tumors of MEN 2a
gram + bacteria that requires NAD and hemin for growth

22. Hairless skin - dynamic fine touch
intranuclear inclusions seen in herpes simplex encephalitis
etanercept
silver stain of gram negative rods
meissners

23. Combo of inhaled anesthetics & succinylcholine
testicular tumor that can present with gynecomastia
cause of malignant hyperthermia
sumatriptan
kawasaki

24. Weakness - atrophy - fasiculations - decreased reflexes & tone
pt has extended expiratory phase
cause of high pH vaginal discharge
LMN signs
MPTP exposure causes depletion of what NT?

25. Chediak - Higashi
microglia
lysosomal storage disease a/w renal disease
child with partial albinism - peripherial neuropathy - recurrent infections
neutrophils fail to respond to chemotaxic stimuli

26. Normal or candida
cause of low pH vaginal discharge
paraventricular nucleus of hypothalamus
alpha 1 anti - trypsin
TZD (glitazones) MofA

27. Bruton's agammaglobulinemia
solitarius nucleus
defective tyrosine kinase
resembles an onion in cross section
plenta accreta

28. Autosomal dominant
MofA of N- aceylcysteine
brain tumor with psammona bodies
mildly decreased UDPGT
inheritance pattern for all MENs

29. Serotonin
raphe nucleus
whats the V/Q at the base of the lung
most common testicular tumor in infants and children up to 3 years of age
which nerve lifts the eyelid?

30. Rhabdomyoma
anti - platelet antibodies
most common primary cardiac tumor in kiddos
what nerve innervates the muscles of mastication?
fusion inhibitors

31. Medulla
most common lysosomal storage disease
branching rods on oral infection
Where does the dorsal column decussate?
hemangioblastomas of retina/cerebellum/medulla

32. Visual (Lateral for Light)
basal nucleus of Meynert
UMN signs
Lateral geniculate nucleus
LMN signs

33. Achondroplasia
FGFR3 mutation
intranuclear inclusions seen in herpes simplex encephalitis
may lead to multiple personalities
catalase negative

34. Premature detachment of placenta - painful bleeding in 3rd trimester
abruptio placentae
hemosiderinurea and thrombosis
cause of high pH vaginal discharge
brain tumor a/w von hipple - linadu syndrome

35. 3
corneal clouding & MR
whats the V/Q at the apex of the lung
abruptio placentae
Where does the dorsal column decussate?

36. Cowdry type A inclusions
astrocytes
intranuclear inclusions seen in herpes simplex encephalitis
FGFR3 mutation
hallmark sign of COPD

37. Macconkey's agar
opioids antidote
hydatidiform mole with crazy high hCG
Shigella
metformin side effect

38. Tay Sachs
GM2 ganglioside accumulation
most common primary cardiac tumor in kiddos
abruptio placentae
alpha galacosidase A

39. Basilar
iduronidase sulfatase
What artery causes locked in syndrome
lewy body composition
solitarius nucleus

40. Incomplete fusion of processus vaginalis
ependymal cells
hydrocele
3 tumors of MEN 1
myelinates multiple CNS axons

41. Demeclycocycline or water restriction
microglia
Galactocerebrosidase deficiency
treatment for SIADH
whats the V/Q at the base of the lung

42. Inhibits osteoclastic activity
Bisphosphonates MofA
ovarian tumor with elevate hCG
glycine
infliximab

43. PPAR- gamma receptor agonist - which causes improved target cell response to insulin
TZD (glitazones) MofA
smoking emphysema
opioid withdrawal
vasculitis of infants and children - involving coronary arteries

44. 5- fluorouracil
SE: facial flushing
thymidylate synthase
whats the V/Q at the apex of the lung
sulfonylureas side effect

45. Dantrolene (prevents release of calcium from SR of muscle)
ovarian tumor that resembles bladder epithelium
basal nucleus of Meynert
most common breast tumor in women under 25
treatment of malignant hyperthermia

46. Neurofibromatosis
Conn's syndrome
t - PA - streptokinase antidote
lisch nodules
Addison's

47. Cells of BBB
What oncogene is a/w MEN 2a/b
FGFR3 mutation
MPTP exposure causes depletion of what NT?
astrocytes

48. Choriocarcinoma
tumor composed of cytotrophoblasts and syncytiotrophoblasts
alpha 1 anti - trypsin
placenta previa
catalase positive coagulase negative

49. Staph epidermidis - staph sapro
blocks ADP receptors to inhibit platelet aggregation
parietal cells
LTB4
catalase positive coagulase negative

50. Membranous GN
hydatidiform mole with crazy high hCG
HELLP syndrome
spike and dome on microscope
preeclampsia