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USMLE Pathophys

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Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. ITP
rate limiting step in carb digestion
anti - platelet antibodies
most common gyno malignancy
precursor to GABA

2. Brenners tumor
barbituates withdrawal
smoking emphysema
palisading nuclei - locally invasive
ovarian tumor that resembles bladder epithelium

3. Estrogen (causes precocious puberty)
silver stain of gram negative rods
granulosa cell tumor secretes what?
microglia
Lateral geniculate nucleus

4. Bromocriptine
first line for cardiogenic shock
what inhibits prolactin secretion
abruptio placentae
iduronidase sulfatase

5. Deficiency of aldosterone and cortisol

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6. Alpha synuclein
honey crusted lesions common around nose/lips
sturge weber syndrome
lewy body composition
hemangioblastomas of retina/cerebellum/medulla

7. HTN - proteinuria - edema
preeclampsia
psammoma bodies
basal nucleus of Meynert
optically clear nuclei (orphan annie)

8. HTN; masculinization
LTB4
11 beta hydroxylase deficiency
What artery causes locked in syndrome
oligodendrioglia

9. Chronic gout. inhibits reabsorbtion of uric acid in PCT
probenecid
What artery causes locked in syndrome
brain tumor with psammona bodies
sumatriptan

10. Neurofibromatosis
oligohydramnios
silver stain of gram negative rods
blocks ADP receptors to inhibit platelet aggregation
lisch nodules

11. Marfans
barbituates withdrawal
floppy mitral valve dissecting aortic aneurysm - berry aneurysm
testicular tumor that can present with gynecomastia
protease inhibitors MofA

12. Granulosa cell tumor
diphtheria treatment
ovarian tumor with elevate hCG
drug induced lupus
tumor with call - exner bodies

13. Hypoglycemia
epithelial
sulfonylureas side effect
LT C4 D4 E4
hemosiderinurea + thrombosis

14. H. Influenza
Lewy bodies composition
gram + bacteria that requires NAD and hemin for growth
most common gyno malignancy
absent UTPGT

15. Niemann Pick
GM2 ganglioside accumulation
sphingomyelinase deficiency
cause of high pH vaginal discharge
neutrophils fail to respond to chemotaxic stimuli

16. B. fragilis
papillary thyroid cancer
ependymal cells
meissners
most common bacteria in GI tract

17. SCID
child with eczema - coarse facial features - cold abscesses
cause of LH surge
looks like fried eggs under histologic staining
protease inhibitors MofA

18. Invasive ductal
whats the V/Q at the apex of the lung
most common breast cancer
ambiguous nucleus
dorsal motor nucleus

19. Glutamate
hep B seropositivity in 30% of patients
beta glucocerebrosidase
precursor to GABA
iduronidase sulfatase

20. SICK PEG
most common testicular tumor
P450 Inhibitors
most common gyno malignancy
tumor with call - exner bodies

21. Secretin
copper - arsenic - gold antidote
hemosiderinurea and thrombosis
pseudopalisading necrosis
S cells

22. A/w esophageal/duodenal atresia and anencephaly
Conn's syndrome
polyhydramnios
microglia
drug induced lupus

23. Macrolides
antibiotic with SE of eosinophilia
most common primary cardiac tumor in kiddos
lewy body composition
sulfonylureas side effect

24. Dubin Johnson
most common testicular tumor
Aschoff bodies
microglia
grossly black liver

25. Impetigo
MofA Levothyroxine
cause of malignant hyperthermia
honey crusted lesions common around nose/lips
cough - conjunctivitis - coryza - fever

26. Von Hippel Lindau
child with partial albinism - peripherial neuropathy - recurrent infections
hemangioblastomas of retina/cerebellum/medulla
Abciximab
antibody against philadelphia chromosome

27. Papillary CA of thyroid - meningioma - mesothelioma - serous cystadenocarcinoma of ovary
VA/VL
most common breast mass in postmenopausal women
TZD (glitazones) MofA
psammoma bodies

28. Fibrates/statins
infliximab
SE: elevated LFTS - myositis
meissners
t - PA - streptokinase antidote

29. Anti - TNF antibody - use for RA but watch out for latent TB!
oligodendrioglia
infliximab
solitarius nucleus
melanoma tumor marker

30. Dobutamine
drug induced lupus
most common arrthymia
may lead to multiple personalities
first line for cardiogenic shock

31. Oligodendroglia
looks like fried eggs under histologic staining
silver stain of gram negative rods
thayer martin media
vasculitis a/w Hep B

32. Body sensation
microglia
branching rods on oral infection
ventral posterior nucleus - lateral part
cough - conjunctivitis - coryza - fever

33. Closes K+ channel on B cells causing depolarization and thus calcium influx which causes insulin release
P450 inducers
sulfonylureas MofA
21 hydroxylase deficiency
opioids antidote

34. Damaged in multiple sclerosis
child with partial albinism - peripherial neuropathy - recurrent infections
hallmark sign of COPD
oligodendrioglia
cause of LH surge

35. Visceral sensory
supraoptic nucleus of hypothalamus
most common breast mass in postmenopausal women
What thyroid pathology has an extremely tender thyroid gland
solitarius nucleus

36. Subacute (De Quervain's) thyroiditis
What thyroid pathology has an extremely tender thyroid gland
Bisphosphonates MofA
chief cells
parietal cells

37. Sends autonomic fibers to heart
kluver bucy
dorsal motor nucleus
What anti - hypertensive drug has the side effect of first dose orthostatic hypotension
GABA - glutamine

38. Estrogen
ambiguous nucleus
cause of high pH vaginal discharge
cause of LH surge
deficiency of mannose phosphorylation

39. Clopidogrel - ticoplidine
blocks ADP receptors to inhibit platelet aggregation
Lateral geniculate nucleus
MofA of N- aceylcysteine
anti - mitochondrial antibodies

40. Krabbe's
thyroid cancer associtated with RET oncogene
most common arrthymia
Galactocerebrosidase deficiency
HELLP syndrome

41. Cocain and sumatriptan
basal nucleus of Meynert
Aschoff bodies
What causes coronary vasospasm as a SE?
floppy mitral valve dissecting aortic aneurysm - berry aneurysm

42. Yolk sac
protease inhibitors MofA
most common testicular tumor in infants and children up to 3 years of age
catalase positive coagulase negative
microglia

43. Gauchers
hemangioblastomas of retina/cerebellum/medulla
Galactocerebrosidase deficiency
crinkled paper cytoplasm
found in hairless skin

44. Measles
etanercept
hemosiderinurea and thrombosis
mildly decreased UDPGT
cough - conjunctivitis - coryza - fever

45. Intussception
oligodendrioglia
currant jelly stool
3 tumors of MEN 1
locus ceruleus

46. Ovarian bengin tumor...looks like bladder
corneal clouding & MR
brain tumor with fried egg appearance
brenner tumor
whats the V/Q at the apex of the lung

47. Serotonin
What thyroid pathology has an extremely tender thyroid gland
What hormones share a common alpha subunit
raphe nucleus
pt has extended expiratory phase

48. Decreased FEV/FVC ratio
tumor with call - exner bodies
antibody against philadelphia chromosome
What are the hormone changes seen in menopause
hallmark sign of COPD

49. Cause release of preformed insulin
sulfonylureas
most common primary cardiac tumor in kiddos
pt has extended expiratory phase
found in hairless skin

50. Ethosuximide
first line for absence seizures
most common breast mass in postmenopausal women
resembles an onion in cross section
PGI2 (prostacyclin))

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USMLE Pathophys

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