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Test your basic knowledge |
USMLE Pathophys
Start Test
Study First
Subjects
:
health-sciences
,
usmle
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Dimercaprol
lead antidote
alpha L iduronidase
follicular
shown to slow progression of diabetic neuropathy
2. PPAR- gamma receptor agonist - which causes improved target cell response to insulin
SE: facial flushing
leydig cell tumor
what checkpoint is p53 involved with?
TZD (glitazones) MofA
3. Trigeminal
Shigella
most common breast tumor in women under 25
LTB4
what nerve innervates the muscles of mastication?
4. Macrophages of the CNS
dose response curve with noncompetitive antagonist
Schiller Duval bodies
corneal clouding & MR
microglia
5. Yolk sac
most common testicular tumor in infants and children up to 3 years of age
D cells
cause of high pH vaginal discharge
first line for cardiogenic shock
6. Neutrophil chemotactic agent 'neutrophils arrive B4 others'
branching rods on oral infection
hallmark sign of COPD
subluxation of lens
LTB4
7. PNH
hippocampus
hemosiderinurea and thrombosis
smoking emphysema
Shigella
8. Oligodendrogila
MofA of N- aceylcysteine
cells destroyed in MS
Lateral geniculate nucleus
whats the V/Q at the base of the lung
9. Sulfonamides - hydralazine - isonazid - procainamide - phenytoin
rabies
looks like fried eggs under histologic staining
Lewy bodies composition
drug induced lupus
10. ADPKD
mitral valve prolapse - liver diseae - berry aneurysm
drug that blocks purine synthesis and is metabolized by xanthine oxidase
shown to slow progression of diabetic neuropathy
whats the V/Q at the apex of the lung
11. Membranoproliferative GN
tram - track on microscope
silver stain of gram negative rods
eczema/recurrent infections/thrombocytopenia
lysosomal storage disease a/w renal disease
12. Increases platelet aggregation and vasoconstriction
thromboxane A2
schwann cells
Abciximab
ovarian tumor with elevate hCG
13. Centriacinar
smoking emphysema
brain tumor with perivascular pseudorosettes
most common breast cancer
H. flu
14. HTN; XY will be a girl - XX will lack secondary sex char.
cause of LH surge
17 alpha hydroxylase deficiency
cause of high pH vaginal discharge
anti - epithelial antibodies
15. Papillary CA of thyroid
meissners
opioid withdrawal
optically clear nuclei (orphan annie)
smoking emphysema
16. Measles
enzyme used to conjugate bilirubin
cough - conjunctivitis - coryza - fever
ependymal cells
erythema nodosum
17. Sulfonamides - Isonizid - Cimetidine - Ketoconazole - Erythromyicn - grapefruit juice - protease inhibitors
testicular tumor that can present with gynecomastia
TZD (glitazones) MofA
SICK PEG
alpha 1 anti - trypsin
18. Dantrolene (prevents release of calcium from SR of muscle)
treatment of malignant hyperthermia
locus ceruleus
S cells
deficiency of mannose phosphorylation
19. NE
most common first line agent for septic shock
preeclampsia
SE: torsades de pointes
P450 Inhibitors
20. Anxiety - insomnia - sweating - dilated pupils - piloerection - rhinorrhea
MofA of N- aceylcysteine
Aschoff bodies
strawberry tongue
opioid withdrawal
21. H. Influenza
3 tumors of MEN 1
microglia
gram + bacteria that requires NAD and hemin for growth
Schiller Duval bodies
22. A few levels above the level of entry
hydatidiform mole with crazy high hCG
SE: torsades de pointes
contains ovarian vessels
Where does the spinothalamic decussate?
23. Cocain and sumatriptan
LTB4
placenta previa
What causes coronary vasospasm as a SE?
epithelial
24. Job's or LAD
Abciximab
neutrophils fail to respond to chemotaxic stimuli
von Hippel Lindau disease
copper - arsenic - gold antidote
25. Motor innervation of pharynx - larynx and upper esophagus
ambiguous nucleus
etanercept
raphe nucleus
sturge weber syndrome
26. A/w esophageal/duodenal atresia and anencephaly
benzos antidote
Shigella
absent UTPGT
polyhydramnios
27. Oligodendroglia
looks like fried eggs under histologic staining
tumor composed of cytotrophoblasts and syncytiotrophoblasts
shown to slow progression of diabetic neuropathy
increased MCHC and hemolytic anemia
28. Panacinar
cause of high pH vaginal discharge
propylthiouracil side effects
alpha 1 anti - trypsin
intranuclear inclusions seen in herpes simplex encephalitis
29. Decreased follicles & estrogen with increased FSH & LH
What are the hormone changes seen in menopause
D cells
smoking emphysema
GFAP positive
30. Deficiency of aldosterone and cortisol
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31. Decreased potency - increased Km
most common breast tumor in women under 25
child with partial albinism - peripherial neuropathy - recurrent infections
dose response curve change with competitive antagonist
sarcoma botyroides
32. Brenners tumor
ovarian tumor that resembles bladder epithelium
colchicine
3 tumors of MEN 1
shown to slow progression of diabetic neuropathy
33. Makes oxytocin
BCG PQRS
paraventricular nucleus of hypothalamus
kawasaki
antibody against philadelphia chromosome
34. Increased acini and intralobular fibrosis
sclerosing adenosis
what nerve innervates the muscles of mastication?
17 alpha hydroxylase deficiency
kawasaki
35. Oligosaccaride hydrolase
sphingomyelinase deficiency
rate limiting step in carb digestion
Where does the lateral corticospinal decussate?
failure of endodermal development
36. Chronic gout. inhibits reabsorbtion of uric acid in PCT
S cells
vasculitis a/w Hep B
BCG PQRS
probenecid
37. Cells of BBB
astrocytes
dermatin sulfate accumulation
nucleoside reverse transcriptase inhibitors
treatment of malignant hyperthermia
38. Actinomyces
sulfonylureas MofA
branching rods on oral infection
form multinucleated giant cells in the CNS when infected with HIV
Bisphosphonates MofA
39. Polyarteritis nodosa
supraoptic nucleus of hypothalamus
most common arrthymia
hep B seropositivity in 30% of patients
tumor with call - exner bodies
40. Thryroxine replacement
silver stain of gram negative rods
hippocampus
midshaft break of humerus
MofA Levothyroxine
41. Schwann cells
most common lysosomal storage disease
LMN signs
currant jelly stool
myelinates on PNS
42. Gauchers
thayer martin media
Bisphosphonates MofA
beta glucocerebrosidase
ambiguous nucleus
43. Achondroplasia
sphingomyelinase deficiency
FGFR3 mutation
LTB4
drug that blocks purine synthesis and is metabolized by xanthine oxidase
44. Clopidogrel - ticoplidine
pigmented iris hamartomas - neural tumors
crinkled paper cytoplasm
blocks ADP receptors to inhibit platelet aggregation
P450 Inhibitors
45. Estrogen
antibody against philadelphia chromosome
schwann cells
anti - mitochondrial antibodies
cause of increased myometrial excitability
46. Closes K+ channel on B cells causing depolarization and thus calcium influx which causes insulin release
blood supply for thalamus
ventral posterior nucleus - medial part
thymidylate synthase
sulfonylureas MofA
47. Cause release of preformed insulin
child with partial albinism - peripherial neuropathy - recurrent infections
tumor composed of cytotrophoblasts and syncytiotrophoblasts
sulfonylureas
ovarian tumor with elevate hCG
48. Hereditary spherocytosis
increased MCHC and hemolytic anemia
astrocytes
What causes coronary vasospasm as a SE?
shown to slow progression of diabetic neuropathy
49. NF 1
locus ceruleus
pigmented iris hamartomas - neural tumors
placenta previa
VA/VL
50. Invasive ductal CA
most common breast mass in postmenopausal women
chief cells
looks like fried eggs under histologic staining
infliximab