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USMLE Pathophys

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. A few levels above the level of entry
myelinates on PNS
subluxation of lens
Bisphosphonates MofA
Where does the spinothalamic decussate?

2. Homocystienuria - Marfans
anti - mitochondrial antibodies
fusion inhibitors
subluxation of lens
S cells

3. Lymphoma

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4. Centriacinar
hydrocele
epithelial
kawasaki
smoking emphysema

5. Makes ADH
supraoptic nucleus of hypothalamus
paraventricular nucleus of hypothalamus
locus ceruleus
most common breast mass in pre - menopausal women

6. Glutamate
LT C4 D4 E4
grossly black liver
what checkpoint is p53 involved with?
precursor to GABA

7. Prevents incorporation into host DNA
brain tumor a/w von hipple - linadu syndrome
parietal cells
myelinates on PNS
nucleoside reverse transcriptase inhibitors

8. Medulla
deficiency of mannose phosphorylation
thayer martin media
Where does the lateral corticospinal decussate?
silver stain of gram negative rods

9. Oligodendrioma
best effect on HDL
SE: elevated LFTS - myositis
dose response curve with noncompetitive antagonist
brain tumor with fried egg appearance

10. Facial sensation (Make up on your face)
ventral posterior nucleus - medial part
testicular tumor that can present with gynecomastia
hemangioblastomas of retina/cerebellum/medulla
supraoptic nucleus of hypothalamus

11. Polyarteritis nodosa
SE: elevated LFTS - myositis
vasculitis a/w Hep B
I cells
basal nucleus of Meynert

12. Dantrolene (prevents release of calcium from SR of muscle)
sphingomyelinase deficiency
kawasaki
treatment of malignant hyperthermia
most common breast mass in postmenopausal women

13. Autosomal dominant
lead antidote
oligohydramnios
cancer associated with Hashimoto's thyroiditis
inheritance pattern for all MENs

14. Schwann cells
precursor to GABA
most common breast mass in postmenopausal women
myelinates on PNS
parietal cells

15. Medulloblastoma
G cells
lysosomal storage disease a/w renal disease
solitarius nucleus
homer wright rosettes

16. Membranoproliferative GN
lewy body composition
metformin side effect
tram - track on microscope
cause of LH surge

17. Inner lining of ventricles - make CSF - originate from neuroectoderm
ependymal cells
kluver bucy
fusion inhibitors
placenta previa

18. Damaged in Guillian Barre
contains ovarian vessels
parietal cells
propylthiouracil side effects
schwann cells

19. Oligodendoglia
hydrocele
first line for absence seizures
solitarius nucleus
myelinates multiple CNS axons

20. Sulfonamides - Isonizid - Cimetidine - Ketoconazole - Erythromyicn - grapefruit juice - protease inhibitors
sphingomyelinase deficiency
S cells
diphtheria treatment
SICK PEG

21. Mucocutaneous lymph node syndrome - necrotizing vasculitis - coronary aneurysms - strawberry tongue
kawasaki
blocks ADP receptors to inhibit platelet aggregation
Where does the dorsal column decussate?
schwann cells

22. ACE inhibitors
lisch nodules
tumor with call - exner bodies
SE: facial flushing
shown to slow progression of diabetic neuropathy

23. Niacin
sarcoma botyroides
SE: facial flushing
sphingomyelinase deficiency
GM2 ganglioside accumulation

24. Estrogen
most common arrthymia
oligohydramnios
cause of LH surge
chief cells

25. Memory
first line for cardiogenic shock
medial geniculate nucleus
hippocampus
kawasaki

26. Ach
basal nucleus of Meynert
microglia
hemosiderinurea + thrombosis
sulfonylureas

27. Secretin
plenta accreta
antibiotic with SE of eosinophilia
defective tyrosine kinase
S cells

28. S-100
sturge weber syndrome
microglia
melanoma tumor marker
Conn's syndrome

29. Clopidogrel - ticoplidine
brenner tumor
benzos antidote
blocks ADP receptors to inhibit platelet aggregation
sulfonylureas MofA

30. Posterior communicating - posterior cerebral - anterior choroidal arteries
blood supply for thalamus
antibiotic with SE of eosinophilia
partial mole components
tumor composed of cytotrophoblasts and syncytiotrophoblasts

31. Depolymerizes microtubules - impairing leukocyte chemotaxis and degranulation
infliximab
ovarian tumor that resembles bladder epithelium
sturge weber syndrome
colchicine

32. Hurlers - Hunters
dermatin sulfate accumulation
3 tumors of MEN 1
looks like fried eggs under histologic staining
17 alpha hydroxylase deficiency

33. Microglia
looks like fried eggs under histologic staining
propylthiouracil side effects
astrocytes
form multinucleated giant cells in the CNS when infected with HIV

34. BCG PQRS
P450 inducers
complete mole components
parietal cells
VA/VL

35. Staph epidermidis - staph sapro
D cells
cancer arising from parafollicular C cells
3 tumors of MEN 2b
catalase positive coagulase negative

36. Inhibitory in the brain - stimulatory in the brain
GABA - glutamine
pseudopalisading necrosis
metformin side effect
UMN signs

37. Aminocaproic acid
what meds treat malaria
t - PA - streptokinase antidote
myelinates on PNS
sumatriptan

38. Body sensation
mitral valve prolapse - liver diseae - berry aneurysm
ventral posterior nucleus - lateral part
vasculitis of infants and children - involving coronary arteries
17 alpha hydroxylase deficiency

39. Dimercaprol
looks like fried eggs under histologic staining
spike and dome on microscope
lead antidote
sulfonylureas side effect

40. Hemolysis - elevated LFTs - Low Platelets
placenta previa
Schiller Duval bodies
HELLP syndrome
blocks ADP receptors to inhibit platelet aggregation

41. Meningioma
Conn's syndrome
child with partial albinism - peripherial neuropathy - recurrent infections
brain tumor with psammona bodies
Bisphosphonates MofA

42. Choriocarcinoma or dysgerminoma
What causes coronary vasospasm as a SE?
ovarian tumor with elevate hCG
most common bacteria in GI tract
best effect of triglycerides/VLDL

43. Decreased follicles & estrogen with increased FSH & LH
most common bacteria in GI tract
What are the hormone changes seen in menopause
Shigella
opioids antidote

44. Incomplete fusion of processus vaginalis
hydrocele
whats the V/Q at the base of the lung
most common breast mass in postmenopausal women
inheritance pattern for all MENs

45. Papillary
thyroid cancer associtated with RET oncogene
dose response curve with noncompetitive antagonist
hemosiderinurea + thrombosis
honey crusted lesions common around nose/lips

46. Chloroquine and primaquine
dose response curve with noncompetitive antagonist
cells destroyed in MS
what meds treat malaria
blocks ADP receptors to inhibit platelet aggregation

47. Hemangioblastoma
antibiotic with SE of eosinophilia
5 alpha reductase deficiency
best effect on HDL
brain tumor a/w von hipple - linadu syndrome

48. Cowdry type A inclusions
astrocytes
catalase negative
intranuclear inclusions seen in herpes simplex encephalitis
placenta previa

49. Niemann Pick
enzyme used to conjugate bilirubin
spike and dome on microscope
sphingomyelinase deficiency
sclerosing adenosis

50. Pacinian
resembles an onion in cross section
increased MCHC and hemolytic anemia
honey crusted lesions common around nose/lips
macrolides use (PUS)