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USMLE Pathophys

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Medullary thyroid - pheochromocytoma - parathryoid
chromosome 4
protease inhibitors MofA
3 tumors of MEN 2a
BCG PQRS

2. Amygdala
cancer arising from parafollicular C cells
best effect of triglycerides/VLDL
kluver bucy
subluxation of lens

3. Sulfonamides - hydralazine - isonazid - procainamide - phenytoin
What hormones share a common alpha subunit
drug induced lupus
subluxation of lens
S cells

4. Invasive ductal CA
catalase negative
17 alpha hydroxylase deficiency
hydatidiform mole with crazy high hCG
most common breast mass in postmenopausal women

5. Neurofibromatosis
lisch nodules
3 tumors of MEN 1
intranuclear inclusions seen in herpes simplex encephalitis
MofA of N- aceylcysteine

6. Attachment of placenta to lower uterine segment
first line for absence seizures
What hormones share a common alpha subunit
What causes coronary vasospasm as a SE?
placenta previa

7. Hurlers
smoking emphysema
alpha L iduronidase
deficiency of mannose phosphorylation
D cells

8. Ach
basal nucleus of Meynert
epithelial
ventral posterior nucleus - lateral part
LT C4 D4 E4

9. Gonorrhea
thayer martin media
whats the V/Q at the base of the lung
resembles an onion in cross section
catalase negative

10. Benign - contains Reinke crystals - usually androgen producing
t - PA - streptokinase antidote
SICK PEG
sarcoma botyroides
leydig cell tumor

11. Anxiety - seizures - delirium - life threatening CV collapse
sulfonylureas side effect
barbituates withdrawal
Schiller Duval bodies
master clock for circadian rhythms

12. Hemangioblastoma
What oncogene is a/w MEN 2a/b
17 alpha hydroxylase deficiency
brain tumor a/w von hipple - linadu syndrome
What are the hormone changes seen in menopause

13. Makes oxytocin
intranuclear inclusions seen in herpes simplex encephalitis
paraventricular nucleus of hypothalamus
Bisphosphonates MofA
Where does the dorsal column decussate?

14. Criglar Najar
brain tumor with perivascular pseudorosettes
absent UTPGT
pacinian
SE: elevated LFTS - myositis

15. Bilateral renal agenesis or posterior urethral valves in males
treatment of malignant hyperthermia
first line for absence seizures
best effect on HDL
oligohydramnios

16. Leydig cell tumor
cough - conjunctivitis - coryza - fever
may lead to multiple personalities
infliximab
testicular tumor that can present with gynecomastia

17. H. Influenza
preeclampsia
gram + bacteria that requires NAD and hemin for growth
opioids antidote
deficiency of mannose phosphorylation

18. Visceral sensory
solitarius nucleus
most common first line agent for septic shock
astrocytes
tumor composed of cytotrophoblasts and syncytiotrophoblasts

19. Ovarian bengin tumor...looks like bladder
etanercept
alpha 1 anti - trypsin
cancer associated with Hashimoto's thyroiditis
brenner tumor

20. Serotonin
child with partial albinism - peripherial neuropathy - recurrent infections
raphe nucleus
branching rods on oral infection
preeclampsia

21. Wiscott - Aldrich
currant jelly stool
fusion inhibitors
blocks ADP receptors to inhibit platelet aggregation
eczema/recurrent infections/thrombocytopenia

22. Decreased efficacy - decreased Vmax
microglia
lead antidote
opioid withdrawal
dose response curve with noncompetitive antagonist

23. Papillary
most common bacteria in GI tract
defective tyrosine kinase
What artery causes locked in syndrome
thyroid cancer associtated with RET oncogene

24. Bind viral gp41 subunit
What thyroid pathology has an extremely tender thyroid gland
fusion inhibitors
form multinucleated giant cells in the CNS when infected with HIV
erythema nodosum

25. Oligodendoglia
thayer martin media
silver stain of gram negative rods
cancer associated with Hashimoto's thyroiditis
myelinates multiple CNS axons

26. Alpha synuclein
GFAP positive
diphtheria treatment
myelinates multiple CNS axons
Lewy bodies composition

27. 2 sperm + 1 egg (fetal parts present)
thyroid cancer associtated with RET oncogene
mitral valve prolapse - liver diseae - berry aneurysm
partial mole components
ovarian tumor with psammoma bodies

28. Inhibitory in the SC
basal nucleus of Meynert
cough - conjunctivitis - coryza - fever
What artery causes locked in syndrome
glycine

29. Staph epidermidis - staph sapro
intranuclear inclusions seen in herpes simplex encephalitis
17 alpha hydroxylase deficiency
heparin antidote
catalase positive coagulase negative

30. Pacinian
keratin filled cysts
resembles an onion in cross section
oligodendrioglia
blood supply for thalamus

31. Meissner
ambiguous nucleus
defective tyrosine kinase
found in hairless skin
most common primary cardiac tumor in kiddos

32. Hemangioblastoma
most common testicular tumor
brain tumor with foamy cells and high vascularity
GFAP positive
benzos antidote

33. Obstructive - COPD
pt has extended expiratory phase
enzyme used to conjugate bilirubin
most common arrthymia
lewy body composition

34. Homocystienuria - Marfans
basal nucleus of Meynert
first line for absence seizures
subluxation of lens
Shigella

35. ITP
rabies
anti - platelet antibodies
infliximab
5 alpha reductase deficiency

36. Seminoma
sclerosing adenosis
I cells
most common testicular tumor
cause of increased myometrial excitability

37. Serous cystadenocarcinoma
thymidylate synthase
preeclampsia
ovarian tumor with psammoma bodies
most common bacteria in GI tract

38. Membranous GN
BCG PQRS
plenta accreta
sulfonylureas MofA
spike and dome on microscope

39. TSH - LH - FSH - hCG
child with eczema - coarse facial features - cold abscesses
P450 Inhibitors
tram - track on microscope
What hormones share a common alpha subunit

40. Sotalol - quinidine - cisapride
resembles an onion in cross section
SE: torsades de pointes
blood supply for thalamus
opioid withdrawal

41. Pneumonia - URIs - STDS
glycine
macrolides use (PUS)
most common first line agent for septic shock
17 alpha hydroxylase deficiency

42. Glutamate
most common bacteria in GI tract
bocks PRPP synthetase to block purine synthesis
precursor to GABA
propylthiouracil side effects

43. Hunters
t - PA - streptokinase antidote
nucleoside reverse transcriptase inhibitors
iduronidase sulfatase
most common primary cardiac tumor in kiddos

44. Marfans
blocks ADP receptors to inhibit platelet aggregation
hippocampus
crinkled paper cytoplasm
floppy mitral valve dissecting aortic aneurysm - berry aneurysm

45. Antibody binds to gp2b/3a - preventing aggregation
What artery causes locked in syndrome
Abciximab
blocks ADP receptors to inhibit platelet aggregation
brain tumor a/w von hipple - linadu syndrome

46. Sends autonomic fibers to heart
failure of endodermal development
smoking emphysema
copper - arsenic - gold antidote
dorsal motor nucleus

47. Chocolate agar
ovarian tumor with psammoma bodies
HELLP syndrome
I cells
H. flu

48. Chloroquine and primaquine
what meds treat malaria
first line for absence seizures
mitral valve prolapse - liver diseae - berry aneurysm
Bisphosphonates MofA

49. Inhibits viral assembly
thayer martin media
blocks ADP receptors to inhibit platelet aggregation
palisading nuclei - locally invasive
protease inhibitors MofA

50. Incomplete fusion of processus vaginalis
glycine
hydrocele
SICK PEG
cells destroyed in Guillain Barre