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USMLE Pathophys

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Primary biliary cirrhosis
anti - mitochondrial antibodies
inheritance pattern for all MENs
papillary thyroid cancer
vasculitis a/w Hep B

2. I- cell disease
deficiency of mannose phosphorylation
grossly black liver
beta glucocerebrosidase
hallmark sign of COPD

3. Anti - TNF antibody - use for RA but watch out for latent TB!
most common breast mass in postmenopausal women
dose response curve with noncompetitive antagonist
infliximab
cause of LH surge

4. Sulfonamides - hydralazine - isonazid - procainamide - phenytoin
dorsal motor nucleus
drug induced lupus
most common breast mass in postmenopausal women
midshaft break of humerus

5. Panacinar
Where does the spinothalamic decussate?
alpha 1 anti - trypsin
basal nucleus of Meynert
treatment of malignant hyperthermia

6. Oligodendoglia
myelinates multiple CNS axons
lysosomal storage disease a/w renal disease
master clock for circadian rhythms
11 beta hydroxylase deficiency

7. HTN - proteinuria - edema
mitral valve prolapse - liver diseae - berry aneurysm
currant jelly stool
preeclampsia
kluver bucy

8. Decreases conversion
sulfonylureas MofA
honey crusted lesions common around nose/lips
PTU
antibiotic with SE of eosinophilia

9. Clopidogrel - ticoplidine
blocks ADP receptors to inhibit platelet aggregation
Where does the spinothalamic decussate?
microglia
oligohydramnios

10. Intrinsic factor
parietal cells
P450 inducers
lysosomal storage disease a/w renal disease
adenomyosis

11. Measles
ambiguous nucleus
cough - conjunctivitis - coryza - fever
chief cells
parietal cells

12. Glioblastoma multiforme
treatment of malignant hyperthermia
11 beta hydroxylase deficiency
what cells secrete somatostatin
pseudopalisading necrosis

13. Inhibits osteoclastic activity
locus ceruleus
catalase positive coagulase negative
Bisphosphonates MofA
HELLP syndrome

14. Basal cell carcinoma
hydatidiform mole with crazy high hCG
anti - mitochondrial antibodies
order of nerve blockade
palisading nuclei - locally invasive

15. Macconkey's agar
cancer arising from parafollicular C cells
Shigella
What artery causes locked in syndrome
Where does the lateral corticospinal decussate?

16. Schwann cells
solitarius nucleus
microglia
What artery causes locked in syndrome
cells destroyed in Guillain Barre

17. Combo of inhaled anesthetics & succinylcholine
cause of malignant hyperthermia
kawasaki
chief cells
beta glucocerebrosidase

18. Normal or candida
H. flu
cause of low pH vaginal discharge
mildly decreased UDPGT
thayer martin media

19. ADPKD
mitral valve prolapse - liver diseae - berry aneurysm
What causes coronary vasospasm as a SE?
chromosome 4
What hormones share a common alpha subunit

20. Hairless skin - dynamic fine touch
etanercept
meissners
alpha L iduronidase
mildly decreased UDPGT

21. Demeclycocycline or water restriction
treatment for SIADH
melanoma tumor marker
locus ceruleus
drug induced lupus

22. Leydig cell tumor
enzyme used to conjugate bilirubin
alpha L iduronidase
whats the V/Q at the apex of the lung
testicular tumor that can present with gynecomastia

23. Cell type involved in most ovarian tumors
epithelial
antibody against philadelphia chromosome
lisch nodules
LTB4

24. 2 sperm + 1 egg (fetal parts present)
most common protozoal infection in US
partial mole components
lysosomal storage disease a/w renal disease
G cells

25. Somatostatin
Where does the dorsal column decussate?
D cells
most common first line agent for septic shock
What are the hormone changes seen in menopause

26. Estrogen
cause of LH surge
placenta previa
MPTP exposure causes depletion of what NT?
vasculitis of infants and children - involving coronary arteries

27. Hemangioblastoma
Schiller Duval bodies
deficiency of mannose phosphorylation
drug induced lupus
brain tumor with foamy cells and high vascularity

28. Metachromatic leukodystrophy
lysosomal storage disease - demyelinating disease
Where does the lateral corticospinal decussate?
Lateral geniculate nucleus
lewy body composition

29. Von Hippel Lindau
opioids antidote
ventral posterior nucleus - medial part
hemangioblastomas of retina/cerebellum/medulla
pt has extended expiratory phase

30. 3
nucleoside reverse transcriptase inhibitors
cause of LH surge
whats the V/Q at the apex of the lung
brain tumor with psammona bodies

31. Masculinization - hypovolemic shock
microglia
21 hydroxylase deficiency
opioid withdrawal
glycine

32. Damaged in multiple sclerosis
oligodendrioglia
heXosaminidase
Lewy bodies composition
chromosome 4

33. Naloxone/naltrexone
lysosomal storage disease a/w renal disease
opioids antidote
defective tyrosine kinase
astrocytes

34. Dopamine
antibiotic with SE of eosinophilia
MPTP exposure causes depletion of what NT?
t - PA - streptokinase antidote
PTU

35. Suspensory ligament of ovaries
sphingomyelinase deficiency
vasculitis of infants and children - involving coronary arteries
may lead to multiple personalities
contains ovarian vessels

36. Bilateral renal agenesis or posterior urethral valves in males
oligohydramnios
tumor with call - exner bodies
gram + bacteria that requires NAD and hemin for growth
drug induced lupus

37. Medulla
locus ceruleus
Where does the lateral corticospinal decussate?
Addison's
UMN signs

38. Closes K+ channel on B cells causing depolarization and thus calcium influx which causes insulin release
3 tumors of MEN 2a
sulfonylureas MofA
precursor to GABA
erythema nodosum

39. Pneumonia - URIs - STDS
basal nucleus of Meynert
macrolides use (PUS)
solitarius nucleus
branching rods on oral infection

40. Serotonin
HELLP syndrome
most common breast tumor in women under 25
raphe nucleus
S cells

41. Macrolides
antibiotic with SE of eosinophilia
alpha 1 anti - trypsin
5 alpha reductase deficiency
basal nucleus of Meynert

42. Serous cystadenocarcinoma
ovarian tumor with psammoma bodies
child with eczema - coarse facial features - cold abscesses
ovarian tumor that resembles bladder epithelium
Bisphosphonates MofA

43. Hypoglycemia
follicular
shown to slow progression of diabetic neuropathy
3 tumors of MEN 1
sulfonylureas side effect

44. Dimercaprol
lead antidote
blood supply for thalamus
meissners
HELLP syndrome

45. Kawasaki
anti - epithelial antibodies
vasculitis of infants and children - involving coronary arteries
macrolides use (PUS)
17 alpha hydroxylase deficiency

46. Meningioma
master clock for circadian rhythms
brain tumor with psammona bodies
propylthiouracil side effects
hallmark sign of COPD

47. Fabrys
alpha galacosidase A
cause of malignant hyperthermia
pseudopalisading necrosis
astrocytes

48. Increases platelet aggregation and vasoconstriction
supraoptic nucleus of hypothalamus
pt has extended expiratory phase
thromboxane A2
cough - conjunctivitis - coryza - fever

49. 2 sperm + empty egg (no fetal parts)
complete mole components
x- linked recessive lysosomal storage diseases
sulfonylureas
GFAP positive

50. Lymphoma

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