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USMLE Pathophys

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Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Streptococcus
heparin antidote
catalase negative
spike and dome on microscope
UMN signs

2. Oculomotor
sturge weber syndrome
what meds treat malaria
SE: elevated LFTS - myositis
which nerve lifts the eyelid?

3. Basal cell carcinoma
precursor to GABA
alpha galacosidase A
Abciximab
palisading nuclei - locally invasive

4. Visual (Lateral for Light)
Yolk sac tumor produces...
cause of low pH vaginal discharge
hydrocele
Lateral geniculate nucleus

5. Bind viral gp41 subunit
most common testicular tumor in infants and children up to 3 years of age
cause of high pH vaginal discharge
cause of low pH vaginal discharge
fusion inhibitors

6. Aplastic anemia - rash - agranulocytosis
propylthiouracil side effects
what cells secrete somatostatin
Abciximab
most common bacteria in GI tract

7. Negri bodies
most common protozoal infection in US
defective tyrosine kinase
rabies
psammoma bodies

8. Chediak - Higashi
Lateral geniculate nucleus
cause of high pH vaginal discharge
polyhydramnios
child with partial albinism - peripherial neuropathy - recurrent infections

9. Medulla
colchicine
astrocytes
branching rods on oral infection
Where does the lateral corticospinal decussate?

10. Astrocytoma & glioblastoma multiforme
ovarian tumor that resembles bladder epithelium
GFAP positive
locus ceruleus
partial mole components

11. Granulosa cell tumor
pigmented iris hamartomas - neural tumors
What are the hormone changes seen in menopause
tumor with call - exner bodies
LTB4

12. Impetigo
honey crusted lesions common around nose/lips
mildly decreased UDPGT
cause of malignant hyperthermia
astrocytes

13. Dantrolene (prevents release of calcium from SR of muscle)
first line for cardiogenic shock
treatment of malignant hyperthermia
chief cells
alpha 1 anti - trypsin

14. Damaged in multiple sclerosis
BCG PQRS
dorsal motor nucleus
oligodendrioglia
t - PA - streptokinase antidote

15. Gauchers
hippocampus
probenecid
crinkled paper cytoplasm
sclerosing adenosis

16. Oligodendoglia
most common lysosomal storage disease
myelinates multiple CNS axons
most common testicular tumor in infants and children up to 3 years of age
17 alpha hydroxylase deficiency

17. Legionella
hydatidiform mole with crazy high hCG
sulfonylureas MofA
silver stain of gram negative rods
SE: elevated LFTS - myositis

18. Facial sensation (Make up on your face)
ventral posterior nucleus - medial part
hallmark sign of COPD
beta glucocerebrosidase
cause of LH surge

19. Cowdry type A inclusions
What thyroid pathology has an extremely tender thyroid gland
intranuclear inclusions seen in herpes simplex encephalitis
cause of increased myometrial excitability
preeclampsia

20. Chocolate agar
crinkled paper cytoplasm
H. flu
Lateral geniculate nucleus
anti - platelet antibodies

21. Medulla
parietal cells
Where does the dorsal column decussate?
preeclampsia
optically clear nuclei (orphan annie)

22. 2 sperm + empty egg (no fetal parts)
cause of low pH vaginal discharge
complete mole components
dorsal motor nucleus
neutrophils fail to respond to chemotaxic stimuli

23. 6- mecaptopurine (metabolized by xanthine oxidase)
hallmark sign of COPD
basal nucleus of Meynert
ovarian tumor that resembles bladder epithelium
bocks PRPP synthetase to block purine synthesis

24. Medulloblastoma
hep B seropositivity in 30% of patients
sturge weber syndrome
homer wright rosettes
von Hippel Lindau disease

25. Depolymerizes microtubules - impairing leukocyte chemotaxis and degranulation
tumor with call - exner bodies
colchicine
subluxation of lens
ventral posterior nucleus - medial part

26. ACE inhibitors
mildly decreased UDPGT
Where does the lateral corticospinal decussate?
HELLP syndrome
shown to slow progression of diabetic neuropathy

27. Secretin
What thyroid pathology has an extremely tender thyroid gland
S cells
blood supply for thalamus
found in hairless skin

28. Sends autonomic fibers to heart
drug induced lupus
FGFR3 mutation
H. flu
dorsal motor nucleus

29. PPAR- gamma receptor agonist - which causes improved target cell response to insulin
Lewy bodies composition
pt has extended expiratory phase
21 hydroxylase deficiency
TZD (glitazones) MofA

30. 2 sperm + 1 egg (fetal parts present)
most common breast cancer
shown to slow progression of diabetic neuropathy
partial mole components
What causes coronary vasospasm as a SE?

31. Anxiety - seizures - delirium - life threatening CV collapse
hallmark sign of COPD
barbituates withdrawal
Yolk sac tumor produces...
melanoma tumor marker

32. Membranoproliferative GN
partial mole components
tram - track on microscope
most common breast mass in postmenopausal women
rabies

33. Ach
chromosome 4
glycine
basal nucleus of Meynert
benzos antidote

34. Attachment of placenta to lower uterine segment
x- linked recessive lysosomal storage diseases
solitarius nucleus
S cells
placenta previa

35. Pepsin
most common gyno malignancy
chief cells
What are the hormone changes seen in menopause
What causes coronary vasospasm as a SE?

36. Fibrocystic
basal nucleus of Meynert
most common breast mass in pre - menopausal women
protease inhibitors MofA
thyroid cancer associtated with RET oncogene

37. Fibrates/statins
most common breast mass in pre - menopausal women
protease inhibitors MofA
SE: elevated LFTS - myositis
x- linked recessive lysosomal storage diseases

38. Antitoxin - penicillin - DPT vaccine
diphtheria treatment
most common protozoal infection in US
microglia
macrolides use (PUS)

39. Dopamine
MPTP exposure causes depletion of what NT?
lewy body composition
PTU
palisading nuclei - locally invasive

40. Brenners tumor
H. flu
ovarian tumor that resembles bladder epithelium
catalase negative
most common protozoal infection in US

41. PNH
hemosiderinurea + thrombosis
parietal cells
ovarian tumor with elevate hCG
3 tumors of MEN 1

42. Imabtinib
barbituates withdrawal
drug that blocks purine synthesis and is metabolized by xanthine oxidase
LMN signs
antibody against philadelphia chromosome

43. ADPKD
most common arrthymia
thyroid cancer associtated with RET oncogene
found in hairless skin
mitral valve prolapse - liver diseae - berry aneurysm

44. Von Hippel Lindau
hemangioblastomas of retina/cerebellum/medulla
partial mole components
pacinian
chief cells

45. Fibroadenoma
sclerosing adenosis
paraventricular nucleus of hypothalamus
most common breast tumor in women under 25
D cells

46. NE
21 hydroxylase deficiency
TZD (glitazones) MofA
locus ceruleus
homer wright rosettes

47. Membranous GN
master clock for circadian rhythms
pigmented iris hamartomas - neural tumors
blocks ADP receptors to inhibit platelet aggregation
spike and dome on microscope

48. Radial nerve - deep brachial artery
follicular
midshaft break of humerus
BCG PQRS
leydig cell tumor

49. Makes ADH
failure of endodermal development
SE: elevated LFTS - myositis
supraoptic nucleus of hypothalamus
3 tumors of MEN 2a

50. Mucocutaneous lymph node syndrome - necrotizing vasculitis - coronary aneurysms - strawberry tongue
5 alpha reductase deficiency
kawasaki
P450 Inhibitors
whats the V/Q at the base of the lung

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USMLE Pathophys

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