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USMLE Pathophys

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Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Brenners tumor
ovarian tumor that resembles bladder epithelium
Aschoff bodies
cancer arising from parafollicular C cells
microglia

2. Decreased follicles & estrogen with increased FSH & LH
What thyroid pathology has an extremely tender thyroid gland
low dose ASA effects - intermediate dose - high dose
keratin filled cysts
What are the hormone changes seen in menopause

3. Oligodendrioma
sumatriptan
what checkpoint is p53 involved with?
alpha 1 anti - trypsin
brain tumor with fried egg appearance

4. Cowdry type A inclusions
intranuclear inclusions seen in herpes simplex encephalitis
brenner tumor
what inhibits prolactin secretion
gram + bacteria that requires NAD and hemin for growth

5. Pacinian
optically clear nuclei (orphan annie)
resembles an onion in cross section
x- linked recessive lysosomal storage diseases
sulfonylureas MofA

6. Von Hippel Lindau
G cells
neutrophils fail to respond to chemotaxic stimuli
hemangioblastomas of retina/cerebellum/medulla
cause of high pH vaginal discharge

7. PNH
11 beta hydroxylase deficiency
sclerosing adenosis
hemosiderinurea and thrombosis
lysosomal storage disease a/w renal disease

8. I- cell disease
hep B seropositivity in 30% of patients
what inhibits prolactin secretion
whats the V/Q at the apex of the lung
deficiency of mannose phosphorylation

9. Antibody binds to gp2b/3a - preventing aggregation
Abciximab
P450 Inhibitors
thayer martin media
myelinates multiple CNS axons

10. Membranous GN
complete mole components
currant jelly stool
dose response curve change with competitive antagonist
spike and dome on microscope

11. Depolymerizes microtubules - impairing leukocyte chemotaxis and degranulation
colchicine
MPTP exposure causes depletion of what NT?
cells destroyed in MS
vasculitis a/w Hep B

12. Damaged in multiple sclerosis
H. flu
oligodendrioglia
brain tumor with fried egg appearance
silver stain of gram negative rods

13. Somatostatin
ventral posterior nucleus - medial part
D cells
P450 Inhibitors
enzyme used to conjugate bilirubin

14. Basilar
granulosa cell tumor secretes what?
benzos antidote
What artery causes locked in syndrome
P450 inducers

15. Bruton's agammaglobulinemia
silver stain of gram negative rods
hallmark sign of COPD
defective tyrosine kinase
found in hairless skin

16. Aminocaproic acid
locus ceruleus
t - PA - streptokinase antidote
most common breast mass in postmenopausal women
meissners

17. Membranoproliferative GN
tram - track on microscope
G cells
ovarian tumor with elevate hCG
cause of LH surge

18. Medulla
solitarius nucleus
Where does the lateral corticospinal decussate?
shown to slow progression of diabetic neuropathy
cough - conjunctivitis - coryza - fever

19. Dopamine
MPTP exposure causes depletion of what NT?
most common testicular tumor
3 tumors of MEN 1
GABA - glutamine

20. Hypoglycemia
sulfonylureas side effect
rabies
Aschoff bodies
anti - epithelial antibodies

21. CCK
I cells
Yolk sac tumor produces...
alpha galacosidase A
H. flu

22. Mucocutaneous lymph node syndrome - necrotizing vasculitis - coronary aneurysms - strawberry tongue
kawasaki
fusion inhibitors
hemangioblastomas of retina/cerebellum/medulla
hemosiderinurea + thrombosis

23. Oculomotor
hydatidiform mole with crazy high hCG
Where does the dorsal column decussate?
palisading nuclei - locally invasive
which nerve lifts the eyelid?

24. Second most common type of thyroid cancer
tumor with call - exner bodies
GABA - glutamine
testicular tumor that can present with gynecomastia
follicular

25. Hereditary spherocytosis
benzos antidote
UMN signs
found in hairless skin
increased MCHC and hemolytic anemia

26. Bind viral gp41 subunit
microglia
lysosomal storage disease - demyelinating disease
fusion inhibitors
PTU

27. Memory
locus ceruleus
hippocampus
plenta accreta
anti - epithelial antibodies

28. Prevents incorporation into host DNA
kawasaki
papillary thyroid cancer
nucleoside reverse transcriptase inhibitors
alpha L iduronidase

29. Gauchers
palisading nuclei - locally invasive
hemosiderinurea and thrombosis
crinkled paper cytoplasm
probenecid

30. Pemphigus vulgaris
dermatin sulfate accumulation
S cells
What artery causes locked in syndrome
anti - epithelial antibodies

31. Amygdala
strawberry tongue
Where does the spinothalamic decussate?
kluver bucy
hemosiderinurea and thrombosis

32. Actinomyces
branching rods on oral infection
Where does the lateral corticospinal decussate?
SE: elevated LFTS - myositis
most common gyno malignancy

33. Cant convert testosterone to DHT - ambiguous genitalia until puberty then penis at 12
beta glucocerebrosidase
5 alpha reductase deficiency
cause of malignant hyperthermia
vasculitis a/w Hep B

34. A few levels above the level of entry
ventral posterior nucleus - lateral part
heXosaminidase
brain tumor with perivascular pseudorosettes
Where does the spinothalamic decussate?

35. SCID
What thyroid pathology has an extremely tender thyroid gland
basal nucleus of Meynert
myelinates multiple CNS axons
child with eczema - coarse facial features - cold abscesses

36. Sends autonomic fibers to heart
ventral posterior nucleus - lateral part
resembles an onion in cross section
tumor with call - exner bodies
dorsal motor nucleus

37. Wiscott - Aldrich
eczema/recurrent infections/thrombocytopenia
rabies
what inhibits prolactin secretion
basal nucleus of Meynert

38. Serotonin
raphe nucleus
Lateral geniculate nucleus
barbituates withdrawal
nucleoside reverse transcriptase inhibitors

39. Endometrial CA
most common bacteria in GI tract
Lewy bodies composition
most common gyno malignancy
what checkpoint is p53 involved with?

40. Posterior communicating - posterior cerebral - anterior choroidal arteries
most common breast mass in postmenopausal women
barbituates withdrawal
GFAP positive
blood supply for thalamus

41. Hemangioblastoma
myelinates multiple CNS axons
brain tumor a/w von hipple - linadu syndrome
form multinucleated giant cells in the CNS when infected with HIV
grossly black liver

42. Hunters
iduronidase sulfatase
brain tumor with foamy cells and high vascularity
corneal clouding & MR
SE: facial flushing

43. Kawasaki
drug induced lupus
vasculitis of infants and children - involving coronary arteries
3 tumors of MEN 1
TZD (glitazones) MofA

44. Increases platelet aggregation and vasoconstriction
thromboxane A2
spike and dome on microscope
erythema nodosum
catalase negative

45. Facial sensation (Make up on your face)
catalase positive coagulase negative
3 tumors of MEN 2b
may lead to multiple personalities
ventral posterior nucleus - medial part

46. PPAR- gamma receptor agonist - which causes improved target cell response to insulin
TZD (glitazones) MofA
sclerosing adenosis
hippocampus
whats the V/Q at the apex of the lung

47. Hurlers - Hunters
dermatin sulfate accumulation
chief cells
sulfonylureas MofA
most common gyno malignancy

48. Hemolysis - elevated LFTs - Low Platelets
may lead to multiple personalities
lysosomal storage disease - demyelinating disease
meissners
HELLP syndrome

49. Imabtinib
schwann cells
tumor composed of cytotrophoblasts and syncytiotrophoblasts
antibody against philadelphia chromosome
colchicine

50. Visual (Lateral for Light)
order of nerve blockade
dorsal motor nucleus
dose response curve change with competitive antagonist
Lateral geniculate nucleus

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USMLE Pathophys

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