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USMLE Pathophys

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. PNH
most common breast cancer
most common lysosomal storage disease
hemosiderinurea and thrombosis
best effect on HDL

2. Membranoproliferative GN
master clock for circadian rhythms
lewy body composition
tram - track on microscope
drug that blocks purine synthesis and is metabolized by xanthine oxidase

3. Niacins
thayer martin media
best effect on HDL
Lateral geniculate nucleus
eczema/recurrent infections/thrombocytopenia

4. Dimercaprol
cause of low pH vaginal discharge
best effect on HDL
lead antidote
kluver bucy

5. Thryroxine replacement
catalase positive coagulase negative
MPTP exposure causes depletion of what NT?
MofA Levothyroxine
5 alpha reductase deficiency

6. Causes vasoconstriction (use for acute migraines)
sumatriptan
MPTP exposure causes depletion of what NT?
spike and dome on microscope
what cells secrete somatostatin

7. Inflammatory lesions of subq fat - usually on anterior shins. a/w infections
chief cells
P450 Inhibitors
what nerve innervates the muscles of mastication?
erythema nodosum

8. Papillary CA of thyroid
optically clear nuclei (orphan annie)
Abciximab
SE: facial flushing
What artery causes locked in syndrome

9. Ach
basal nucleus of Meynert
D cells
catalase positive coagulase negative
ovarian tumor that resembles bladder epithelium

10. Cocain and sumatriptan
leydig cell tumor
What causes coronary vasospasm as a SE?
brenner tumor
cause of low pH vaginal discharge

11. Polyarteritis nodosa
vasculitis a/w Hep B
complete mole components
sulfonylureas MofA
solitarius nucleus

12. Yolk sac
sulfonylureas MofA
sulfonylureas
most common testicular tumor in infants and children up to 3 years of age
defective tyrosine kinase

13. Glutamate
Where does the spinothalamic decussate?
branching rods on oral infection
precursor to GABA
what checkpoint is p53 involved with?

14. G1/S & G2/M
what meds treat malaria
alpha 1 anti - trypsin
x- linked recessive lysosomal storage diseases
what checkpoint is p53 involved with?

15. Medulloblastoma
ependymal cells
chief cells
homer wright rosettes
Lewy bodies composition

16. Primary hyperaldosteronism (HTN - hypokalemia - metabolic alkalosis)

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17. Actinomyces
pt has extended expiratory phase
solitarius nucleus
BCG PQRS
branching rods on oral infection

18. Parathyroid - pituitary - pancreatic
Shigella
alpha 1 anti - trypsin
3 tumors of MEN 1
anti - epithelial antibodies

19. S-100
melanoma tumor marker
PTU
Addison's
heparin antidote

20. Tay SaX
thromboxane A2
heXosaminidase
currant jelly stool
17 alpha hydroxylase deficiency

21. Hurlers
corneal clouding & MR
cause of malignant hyperthermia
3 tumors of MEN 2a
ovarian tumor that resembles bladder epithelium

22. Dantrolene (prevents release of calcium from SR of muscle)
rabies
UMN signs
treatment of malignant hyperthermia
thyroid cancer associtated with RET oncogene

23. Second most common type of thyroid cancer
SE: torsades de pointes
resembles an onion in cross section
follicular
spike and dome on microscope

24. Motor innervation of pharynx - larynx and upper esophagus
lisch nodules
ambiguous nucleus
anti - epithelial antibodies
copper - arsenic - gold antidote

25. Invasive ductal CA
most common breast mass in postmenopausal women
hemosiderinurea and thrombosis
what checkpoint is p53 involved with?
Aschoff bodies

26. Gilberts
cause of increased myometrial excitability
mildly decreased UDPGT
antibiotic with SE of eosinophilia
alpha 1 anti - trypsin

27. Glucuronyl transferase
catalase positive coagulase negative
enzyme used to conjugate bilirubin
heXosaminidase
kawasaki

28. Inhibitory in the SC
glycine
UMN signs
Abciximab
master clock for circadian rhythms

29. D cells of pancreas and gut
what cells secrete somatostatin
colchicine
copper - arsenic - gold antidote
child with eczema - coarse facial features - cold abscesses

30. Dobutamine
most common breast tumor in women under 25
preeclampsia
barbituates withdrawal
first line for cardiogenic shock

31. Meissner
cancer arising from parafollicular C cells
drug that blocks purine synthesis and is metabolized by xanthine oxidase
found in hairless skin
smoking emphysema

32. NE
most common first line agent for septic shock
strawberry tongue
What causes coronary vasospasm as a SE?
Addison's

33. Pemphigus vulgaris
anti - epithelial antibodies
epithelial
kluver bucy
thromboxane A2

34. Gauchers
brenner tumor
crinkled paper cytoplasm
cancer arising from parafollicular C cells
PTU

35. Flumazenil
basal nucleus of Meynert
dermatin sulfate accumulation
floppy mitral valve dissecting aortic aneurysm - berry aneurysm
benzos antidote

36. Anxiety - seizures - delirium - life threatening CV collapse
macrolides use (PUS)
leydig cell tumor
barbituates withdrawal
smoking emphysema

37. Babinski - weakness - increased reflexes & tone - spastic paralysis
sulfonylureas MofA
UMN signs
preeclampsia
vasculitis a/w Hep B

38. Fibrocystic
brain tumor with fried egg appearance
most common breast mass in pre - menopausal women
cause of increased myometrial excitability
cause of malignant hyperthermia

39. TNF receptor
Conn's syndrome
vasculitis a/w Hep B
erythema nodosum
etanercept

40. A/w esophageal/duodenal atresia and anencephaly
polyhydramnios
copper - arsenic - gold antidote
what nerve innervates the muscles of mastication?
gram + bacteria that requires NAD and hemin for growth

41. Increased acini and intralobular fibrosis
basal nucleus of Meynert
papillary thyroid cancer
t - PA - streptokinase antidote
sclerosing adenosis

42. Inhibits osteoclastic activity
Bisphosphonates MofA
myelinates multiple CNS axons
solitarius nucleus
PGI2 (prostacyclin))

43. Subacute (De Quervain's) thyroiditis
3 tumors of MEN 2a
gram + bacteria that requires NAD and hemin for growth
MPTP exposure causes depletion of what NT?
What thyroid pathology has an extremely tender thyroid gland

44. Obstructive - COPD
spike and dome on microscope
silver stain of gram negative rods
PGI2 (prostacyclin))
pt has extended expiratory phase

45. Gauchers
metformin side effect
Shigella
P450 Inhibitors
most common lysosomal storage disease

46. Choriocarcinoma
parietal cells
tumor composed of cytotrophoblasts and syncytiotrophoblasts
beta glucocerebrosidase
SICK PEG

47. Mucocutaneous lymph node syndrome - necrotizing vasculitis - coronary aneurysms - strawberry tongue
kawasaki
most common breast mass in postmenopausal women
papillary thyroid cancer
What thyroid pathology has an extremely tender thyroid gland

48. Serotonin
rate limiting step in carb digestion
H. flu
raphe nucleus
ovarian tumor with elevate hCG

49. A few levels above the level of entry
increased MCHC and hemolytic anemia
Where does the spinothalamic decussate?
tumor composed of cytotrophoblasts and syncytiotrophoblasts
drug that blocks purine synthesis and is metabolized by xanthine oxidase

50. Weakness - atrophy - fasiculations - decreased reflexes & tone
catalase negative
inheritance pattern for all MENs
anti - epithelial antibodies
LMN signs