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USMLE Pathophys

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Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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1. Inhibitory in the SC
What hormones share a common alpha subunit
dose response curve with noncompetitive antagonist
ovarian tumor that resembles bladder epithelium
glycine

2. Cant convert testosterone to DHT - ambiguous genitalia until puberty then penis at 12
dose response curve with noncompetitive antagonist
P450 inducers
thymidylate synthase
5 alpha reductase deficiency

3. Makes oxytocin
honey crusted lesions common around nose/lips
LMN signs
psammoma bodies
paraventricular nucleus of hypothalamus

4. I- cell disease
TZD (glitazones) MofA
heparin antidote
deficiency of mannose phosphorylation
metformin side effect

5. Intrinsic factor
rabies
parietal cells
most common breast cancer
schwann cells

6. Fabry's
low dose ASA effects - intermediate dose - high dose
astrocytes
deficiency of mannose phosphorylation
lysosomal storage disease a/w renal disease

7. Decreases conversion
gram + bacteria that requires NAD and hemin for growth
PTU
antibody against philadelphia chromosome
infliximab

8. Second most common type of thyroid cancer
11 beta hydroxylase deficiency
follicular
order of nerve blockade
most common breast mass in postmenopausal women

9. Mucocutaneous lymph node syndrome - necrotizing vasculitis - coronary aneurysms - strawberry tongue
hippocampus
currant jelly stool
sphingomyelinase deficiency
kawasaki

10. Subacute (De Quervain's) thyroiditis
solitarius nucleus
What thyroid pathology has an extremely tender thyroid gland
sarcoma botyroides
MofA of N- aceylcysteine

11. Cowdry type A inclusions
intranuclear inclusions seen in herpes simplex encephalitis
epithelial
abruptio placentae
lewy body composition

12. Polyarteritis nodosa
brain tumor a/w von hipple - linadu syndrome
corneal clouding & MR
vasculitis a/w Hep B
What oncogene is a/w MEN 2a/b

13. Sotalol - quinidine - cisapride
tumor composed of cytotrophoblasts and syncytiotrophoblasts
ovarian tumor with elevate hCG
hemosiderinurea + thrombosis
SE: torsades de pointes

14. Sulfonamides - Isonizid - Cimetidine - Ketoconazole - Erythromyicn - grapefruit juice - protease inhibitors
SE: facial flushing
child with eczema - coarse facial features - cold abscesses
SICK PEG
silver stain of gram negative rods

15. Benign - contains Reinke crystals - usually androgen producing
most common bacteria in GI tract
Bisphosphonates MofA
leydig cell tumor
looks like fried eggs under histologic staining

16. Alpha feto protein
SE: elevated LFTS - myositis
GABA - glutamine
drug that blocks purine synthesis and is metabolized by xanthine oxidase
Yolk sac tumor produces...

17. Papillary CA of thyroid
hemosiderinurea + thrombosis
grossly black liver
optically clear nuclei (orphan annie)
placenta previa

18. Oculomotor
P450 inducers
pt has extended expiratory phase
which nerve lifts the eyelid?
optically clear nuclei (orphan annie)

19. 0.6
whats the V/Q at the base of the lung
SE: elevated LFTS - myositis
shown to slow progression of diabetic neuropathy
branching rods on oral infection

20. Serous cystadenocarcinoma
cause of low pH vaginal discharge
Galactocerebrosidase deficiency
ovarian tumor with psammoma bodies
failure of endodermal development

21. Trichomonas or bacterial vaginosis
cause of high pH vaginal discharge
locus ceruleus
S cells
What causes coronary vasospasm as a SE?

22. Kawasaki (treat with high dose aspirin)
kawasaki
strawberry tongue
hippocampus
lead antidote

23. B. fragilis
whats the V/Q at the base of the lung
most common bacteria in GI tract
hemangioblastomas of retina/cerebellum/medulla
ovarian tumor that resembles bladder epithelium

24. Medullary
ambiguous nucleus
what checkpoint is p53 involved with?
cancer arising from parafollicular C cells
antibody against philadelphia chromosome

25. Oligodendroglia
follicular
propylthiouracil side effects
looks like fried eggs under histologic staining
supraoptic nucleus of hypothalamus

26. Seborric keratosis
cause of high pH vaginal discharge
treatment of malignant hyperthermia
brain tumor with fried egg appearance
keratin filled cysts

27. Niacin
SE: facial flushing
drug induced lupus
enzyme used to conjugate bilirubin
propylthiouracil side effects

28. Endometrial CA
sphingomyelinase deficiency
P450 inducers
most common gyno malignancy
melanoma tumor marker

29. Damaged in Guillian Barre
most common gyno malignancy
brain tumor with perivascular pseudorosettes
drug that blocks purine synthesis and is metabolized by xanthine oxidase
schwann cells

30. Medulloblastoma
enzyme used to conjugate bilirubin
most common breast tumor in women under 25
deficiency of mannose phosphorylation
homer wright rosettes

31. Dopamine
MPTP exposure causes depletion of what NT?
Schiller Duval bodies
increased MCHC and hemolytic anemia
most common gyno malignancy

32. Neutrophil chemotactic agent 'neutrophils arrive B4 others'
3 tumors of MEN 1
vasculitis a/w Hep B
child with partial albinism - peripherial neuropathy - recurrent infections
LTB4

33. Most common type of thyroid cancer
hemosiderinurea and thrombosis
papillary thyroid cancer
branching rods on oral infection
cancer associated with Hashimoto's thyroiditis

34. Imabtinib
best effect on HDL
antibody against philadelphia chromosome
complete mole components
crinkled paper cytoplasm

35. Dubin Johnson
grossly black liver
etanercept
sulfonylureas MofA
MofA Levothyroxine

36. Hemangioblastoma
brain tumor with foamy cells and high vascularity
thyroid cancer associtated with RET oncogene
What artery causes locked in syndrome
antibiotic with SE of eosinophilia

37. Lactic acidosis
catalase positive coagulase negative
metformin side effect
partial mole components
FGFR3 mutation

38. Incomplete fusion of processus vaginalis
placenta previa
psammoma bodies
what inhibits prolactin secretion
hydrocele

39. Demeclycocycline or water restriction
myelinates multiple CNS axons
intranuclear inclusions seen in herpes simplex encephalitis
lysosomal storage disease - demyelinating disease
treatment for SIADH

40. Pepsin
form multinucleated giant cells in the CNS when infected with HIV
chief cells
cells destroyed in MS
low dose ASA effects - intermediate dose - high dose

41. Huntingtons chorea
whats the V/Q at the apex of the lung
most common gyno malignancy
what nerve innervates the muscles of mastication?
chromosome 4

42. Kawasaki
vasculitis of infants and children - involving coronary arteries
adenomyosis
most common testicular tumor in infants and children up to 3 years of age
cells destroyed in MS

43. Function as bronchoconstrictors - vasoconstrictors - sm mm contraction and increased vascular permability
hemosiderinurea and thrombosis
LT C4 D4 E4
lysosomal storage disease - demyelinating disease
lisch nodules

44. Criglar Najar
placenta previa
absent UTPGT
chief cells
GFAP positive

45. Hurlers - Hunters
ovarian tumor with psammoma bodies
crinkled paper cytoplasm
What artery causes locked in syndrome
dermatin sulfate accumulation

46. Hurlers
precursor to GABA
alpha L iduronidase
Abciximab
schwann cells

47. Schwann cells
What causes coronary vasospasm as a SE?
myelinates on PNS
blocks ADP receptors to inhibit platelet aggregation
UMN signs

48. Increases platelet aggregation and vasoconstriction
corneal clouding & MR
follicular
what checkpoint is p53 involved with?
thromboxane A2

49. Normal or candida
sulfonylureas side effect
thromboxane A2
cause of low pH vaginal discharge
Bisphosphonates MofA

50. Amygdala
absent UTPGT
LTB4
kluver bucy
abruptio placentae

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USMLE Pathophys

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