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USMLE Pathophys

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Body sensation
infliximab
child with partial albinism - peripherial neuropathy - recurrent infections
ventral posterior nucleus - lateral part
crinkled paper cytoplasm

2. Atrial fibrillation
sclerosing adenosis
most common primary cardiac tumor in kiddos
opioid withdrawal
most common arrthymia

3. Lymphoma

4. Makes ADH
supraoptic nucleus of hypothalamus
dermatin sulfate accumulation
Shigella
LMN signs

5. Combo of inhaled anesthetics & succinylcholine
cause of malignant hyperthermia
D cells
whats the V/Q at the base of the lung
lysosomal storage disease - demyelinating disease

6. Inhibitory in the brain - stimulatory in the brain
most common testicular tumor
astrocytes
GABA - glutamine
parietal cells

7. Bind viral gp41 subunit
blocks ADP receptors to inhibit platelet aggregation
granulosa cell tumor secretes what?
fusion inhibitors
smoking emphysema

8. Tay Sachs
nucleoside reverse transcriptase inhibitors
dose response curve with noncompetitive antagonist
most common lysosomal storage disease
GM2 ganglioside accumulation

9. Hairless skin - dynamic fine touch
meissners
erythema nodosum
thromboxane A2
supraoptic nucleus of hypothalamus

10. Dubin Johnson
grossly black liver
child with eczema - coarse facial features - cold abscesses
3 tumors of MEN 2a
chief cells

11. ADPKD
partial mole components
mitral valve prolapse - liver diseae - berry aneurysm
protease inhibitors MofA
first line for cardiogenic shock

12. Protamine sulfate
Conn's syndrome
basal nucleus of Meynert
heparin antidote
papillary thyroid cancer

13. Decreased efficacy - decreased Vmax
dose response curve with noncompetitive antagonist
Aschoff bodies
most common protozoal infection in US
SICK PEG

14. 0.6
whats the V/Q at the base of the lung
LTB4
S cells
schwann cells

15. Serous cystadenocarcinoma
treatment of malignant hyperthermia
what inhibits prolactin secretion
17 alpha hydroxylase deficiency
ovarian tumor with psammoma bodies

16. Krabbe's
Galactocerebrosidase deficiency
metformin side effect
SE: torsades de pointes
hemangioblastomas of retina/cerebellum/medulla

17. Streptococcus
currant jelly stool
sphingomyelinase deficiency
catalase negative
treatment of malignant hyperthermia

18. Gauchers
beta glucocerebrosidase
cause of LH surge
colchicine
eczema/recurrent infections/thrombocytopenia

19. Actinomyces
astrocytes
branching rods on oral infection
schwann cells
currant jelly stool

20. B. fragilis
antibody against philadelphia chromosome
most common bacteria in GI tract
palisading nuclei - locally invasive
sumatriptan

21. Decreases conversion
treatment of malignant hyperthermia
P450 Inhibitors
PTU
first line for cardiogenic shock

22. Homocystienuria - Marfans
intranuclear inclusions seen in herpes simplex encephalitis
subluxation of lens
which nerve lifts the eyelid?
vasculitis a/w Hep B

23. Vibration - pressure
vasculitis of infants and children - involving coronary arteries
pacinian
What oncogene is a/w MEN 2a/b
hallmark sign of COPD

24. Yolk sac
most common testicular tumor in infants and children up to 3 years of age
S cells
astrocytes
order of nerve blockade

25. Hemangioblastoma
most common breast cancer
brain tumor a/w von hipple - linadu syndrome
sumatriptan
hemangioblastomas of retina/cerebellum/medulla

26. Hemangioblastoma
pt has extended expiratory phase
SICK PEG
pseudopalisading necrosis
brain tumor with foamy cells and high vascularity

27. Membranoproliferative GN
tram - track on microscope
Yolk sac tumor produces...
oligohydramnios
UMN signs

28. DiGeorge
low dose ASA effects - intermediate dose - high dose
failure of endodermal development
most common testicular tumor in infants and children up to 3 years of age
enzyme used to conjugate bilirubin

29. Basilar
bocks PRPP synthetase to block purine synthesis
ventral posterior nucleus - lateral part
failure of endodermal development
What artery causes locked in syndrome

30. Antibody binds to gp2b/3a - preventing aggregation
leydig cell tumor
What are the hormone changes seen in menopause
Abciximab
astrocytes

31. Glutamate
cause of high pH vaginal discharge
alpha L iduronidase
precursor to GABA
order of nerve blockade

32. Subacute (De Quervain's) thyroiditis
antibody against philadelphia chromosome
opioid withdrawal
Lateral geniculate nucleus
What thyroid pathology has an extremely tender thyroid gland

33. Choriocarcinoma or dysgerminoma
TZD (glitazones) MofA
rabies
ovarian tumor with elevate hCG
ventral posterior nucleus - medial part

34. Masculinization - hypovolemic shock
alpha galacosidase A
21 hydroxylase deficiency
vasculitis of infants and children - involving coronary arteries
pseudopalisading necrosis

35. Trigeminal
Lewy bodies composition
what nerve innervates the muscles of mastication?
propylthiouracil side effects
brain tumor with foamy cells and high vascularity

36. Macrolides
diphtheria treatment
found in hairless skin
antibiotic with SE of eosinophilia
lysosomal storage disease - demyelinating disease

37. Tay SaX
drug induced lupus
heXosaminidase
branching rods on oral infection
What oncogene is a/w MEN 2a/b

38. Medullary thyroid - pheochromocytoma - oral/intestinal ganglionueromatosis
rate limiting step in carb digestion
pacinian
3 tumors of MEN 2b
best effect on HDL

39. HTN - proteinuria - edema
cancer arising from parafollicular C cells
HELLP syndrome
microglia
preeclampsia

40. Metachromatic leukodystrophy
treatment of malignant hyperthermia
intranuclear inclusions seen in herpes simplex encephalitis
lysosomal storage disease - demyelinating disease
leydig cell tumor

41. Kawasaki
sumatriptan
treatment for SIADH
vasculitis of infants and children - involving coronary arteries
nucleoside reverse transcriptase inhibitors

42. Primary hyperaldosteronism (HTN - hypokalemia - metabolic alkalosis)

43. Complete
brain tumor a/w von hipple - linadu syndrome
benzos antidote
I cells
hydatidiform mole with crazy high hCG

44. Hurlers
copper - arsenic - gold antidote
diphtheria treatment
resembles an onion in cross section
alpha L iduronidase

45. ITP
alpha 1 anti - trypsin
most common breast mass in postmenopausal women
anti - platelet antibodies
antibody against philadelphia chromosome

46. Somatostatin
lysosomal storage disease a/w renal disease
paraventricular nucleus of hypothalamus
D cells
granulosa cell tumor secretes what?

47. Secretin
vasculitis of infants and children - involving coronary arteries
LT C4 D4 E4
contains ovarian vessels
S cells

48. Pacinian
SE: torsades de pointes
sarcoma botyroides
adenomyosis
resembles an onion in cross section

49. Decreased FEV/FVC ratio
partial mole components
SE: elevated LFTS - myositis
rate limiting step in carb digestion
hallmark sign of COPD

50. Ach
anti - epithelial antibodies
basal nucleus of Meynert
3 tumors of MEN 2b
branching rods on oral infection