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USMLE Pathophys

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Oculomotor
which nerve lifts the eyelid?
alpha 1 anti - trypsin
LTB4
metformin side effect

2. Small diameter > large diameter; myelinated > unmyelinated
order of nerve blockade
crinkled paper cytoplasm
Where does the spinothalamic decussate?
D cells

3. Superchiasmic nucleus
master clock for circadian rhythms
infliximab
probenecid
SE: facial flushing

4. NE
I cells
Lewy bodies composition
TZD (glitazones) MofA
most common first line agent for septic shock

5. Macrolides
hemangioblastomas of retina/cerebellum/medulla
locus ceruleus
honey crusted lesions common around nose/lips
antibiotic with SE of eosinophilia

6. TNF receptor
etanercept
GABA - glutamine
increased MCHC and hemolytic anemia
keratin filled cysts

7. Homocystienuria - Marfans
dose response curve with noncompetitive antagonist
subluxation of lens
most common first line agent for septic shock
most common primary cardiac tumor in kiddos

8. 3
whats the V/Q at the apex of the lung
sclerosing adenosis
catalase negative
antibiotic with SE of eosinophilia

9. Sends autonomic fibers to heart
papillary thyroid cancer
erythema nodosum
hemosiderinurea and thrombosis
dorsal motor nucleus

10. Negri bodies
hippocampus
rabies
pt has extended expiratory phase
order of nerve blockade

11. SCID
child with eczema - coarse facial features - cold abscesses
eczema/recurrent infections/thrombocytopenia
S cells
order of nerve blockade

12. Intrinsic factor
MofA of N- aceylcysteine
17 alpha hydroxylase deficiency
optically clear nuclei (orphan annie)
parietal cells

13. Krabbe's
Galactocerebrosidase deficiency
SE: facial flushing
resembles an onion in cross section
smoking emphysema

14. Hemangioblastoma
microglia
which nerve lifts the eyelid?
brain tumor with foamy cells and high vascularity
H. flu

15. Estrogen
most common breast cancer
cause of increased myometrial excitability
Where does the spinothalamic decussate?
anti - mitochondrial antibodies

16. NF 1
pigmented iris hamartomas - neural tumors
keratin filled cysts
most common breast mass in postmenopausal women
intranuclear inclusions seen in herpes simplex encephalitis

17. Anxiety - insomnia - sweating - dilated pupils - piloerection - rhinorrhea
corneal clouding & MR
opioid withdrawal
Lateral geniculate nucleus
x- linked recessive lysosomal storage diseases

18. Meissner
smoking emphysema
granulosa cell tumor secretes what?
dose response curve change with competitive antagonist
found in hairless skin

19. Intussception
honey crusted lesions common around nose/lips
leydig cell tumor
iduronidase sulfatase
currant jelly stool

20. Flumazenil
benzos antidote
most common breast cancer
what nerve innervates the muscles of mastication?
cancer arising from parafollicular C cells

21. Rhabdomyoma
most common primary cardiac tumor in kiddos
vasculitis a/w Hep B
Addison's
sclerosing adenosis

22. HTN; masculinization
lead antidote
11 beta hydroxylase deficiency
ovarian tumor that resembles bladder epithelium
sclerosing adenosis

23. Motor
VA/VL
PGI2 (prostacyclin))
D cells
epithelial

24. Tay SaX
palisading nuclei - locally invasive
intranuclear inclusions seen in herpes simplex encephalitis
brain tumor with fried egg appearance
heXosaminidase

25. Primary biliary cirrhosis
anti - mitochondrial antibodies
sturge weber syndrome
thymidylate synthase
rate limiting step in carb digestion

26. Polyarteritis nodosa
GABA - glutamine
hep B seropositivity in 30% of patients
sclerosing adenosis
tram - track on microscope

27. Vaginal carcinoma: spindle shaped tumor cells that are desmin positive
most common primary cardiac tumor in kiddos
supraoptic nucleus of hypothalamus
brain tumor a/w von hipple - linadu syndrome
sarcoma botyroides

28. Babinski - weakness - increased reflexes & tone - spastic paralysis
SE: torsades de pointes
UMN signs
increased MCHC and hemolytic anemia
astrocytes

29. Estrogen
contains ovarian vessels
cause of LH surge
ovarian tumor with elevate hCG
ovarian tumor with psammoma bodies

30. PNH
treatment of malignant hyperthermia
antibody against philadelphia chromosome
hemosiderinurea and thrombosis
protease inhibitors MofA

31. Niemann Pick
sphingomyelinase deficiency
shown to slow progression of diabetic neuropathy
looks like fried eggs under histologic staining
GABA - glutamine

32. Oligodendrogila
TZD (glitazones) MofA
honey crusted lesions common around nose/lips
cells destroyed in MS
drug that blocks purine synthesis and is metabolized by xanthine oxidase

33. Lymphoma

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34. Damaged in multiple sclerosis
SE: elevated LFTS - myositis
PTU
oligodendrioglia
parietal cells

35. Decreases conversion
PTU
mildly decreased UDPGT
brenner tumor
infliximab

36. Streptococcus
kluver bucy
best effect of triglycerides/VLDL
lysosomal storage disease a/w renal disease
catalase negative

37. 5- fluorouracil
chromosome 4
thymidylate synthase
Addison's
placenta previa

38. Pemphigus vulgaris
5 alpha reductase deficiency
anti - epithelial antibodies
SE: torsades de pointes
colchicine

39. Seminoma
abruptio placentae
most common testicular tumor
I cells
SE: facial flushing

40. Papillary CA of thyroid - meningioma - mesothelioma - serous cystadenocarcinoma of ovary
psammoma bodies
crinkled paper cytoplasm
brain tumor with psammona bodies
partial mole components

41. Incomplete fusion of processus vaginalis
myelinates on PNS
macrolides use (PUS)
hydrocele
eczema/recurrent infections/thrombocytopenia

42. Dobutamine
opioids antidote
first line for cardiogenic shock
copper - arsenic - gold antidote
optically clear nuclei (orphan annie)

43. Naloxone/naltrexone
most common arrthymia
FGFR3 mutation
lysosomal storage disease a/w renal disease
opioids antidote

44. Bilateral renal agenesis or posterior urethral valves in males
anti - epithelial antibodies
vasculitis of infants and children - involving coronary arteries
oligohydramnios
Shigella

45. 2 sperm + 1 egg (fetal parts present)
vasculitis a/w Hep B
alpha galacosidase A
sclerosing adenosis
partial mole components

46. Visual (Lateral for Light)
resembles an onion in cross section
Addison's
what cells secrete somatostatin
Lateral geniculate nucleus

47. SICK PEG
P450 Inhibitors
what inhibits prolactin secretion
keratin filled cysts
rate limiting step in carb digestion

48. Estrogen (causes precocious puberty)
granulosa cell tumor secretes what?
SE: facial flushing
FGFR3 mutation
What hormones share a common alpha subunit

49. Job's or LAD
H. flu
drug that blocks purine synthesis and is metabolized by xanthine oxidase
3 tumors of MEN 2b
neutrophils fail to respond to chemotaxic stimuli

50. Chocolate agar
thromboxane A2
21 hydroxylase deficiency
H. flu
What hormones share a common alpha subunit