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USMLE Pathophys

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Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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1. Cocain and sumatriptan
bocks PRPP synthetase to block purine synthesis
thromboxane A2
anti - mitochondrial antibodies
What causes coronary vasospasm as a SE?

2. Fibrates
papillary thyroid cancer
LMN signs
GFAP positive
best effect of triglycerides/VLDL

3. Polyarteritis nodosa
vasculitis a/w Hep B
etanercept
Conn's syndrome
form multinucleated giant cells in the CNS when infected with HIV

4. Pemphigus vulgaris
GM2 ganglioside accumulation
hemosiderinurea + thrombosis
inheritance pattern for all MENs
anti - epithelial antibodies

5. 0.6
sumatriptan
D cells
erythema nodosum
whats the V/Q at the base of the lung

6. Amygdala
kluver bucy
gram + bacteria that requires NAD and hemin for growth
dermatin sulfate accumulation
tumor with call - exner bodies

7. Hereditary spherocytosis
increased MCHC and hemolytic anemia
hep B seropositivity in 30% of patients
chromosome 4
dorsal motor nucleus

8. Hurlers
Abciximab
sulfonylureas side effect
corneal clouding & MR
myelinates multiple CNS axons

9. Combo of inhaled anesthetics & succinylcholine
cause of malignant hyperthermia
What are the hormone changes seen in menopause
whats the V/Q at the base of the lung
brain tumor a/w von hipple - linadu syndrome

10. Prazosin
Aschoff bodies
most common breast cancer
whats the V/Q at the apex of the lung
What anti - hypertensive drug has the side effect of first dose orthostatic hypotension

11. Papillary
child with eczema - coarse facial features - cold abscesses
meissners
most common breast mass in pre - menopausal women
thyroid cancer associtated with RET oncogene

12. Oligodendrogila
strawberry tongue
cells destroyed in MS
antibody against philadelphia chromosome
I cells

13. Bilateral renal agenesis or posterior urethral valves in males
oligohydramnios
PTU
cough - conjunctivitis - coryza - fever
treatment of malignant hyperthermia

14. Deficiency of aldosterone and cortisol

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15. Invasive ductal CA
most common breast mass in postmenopausal women
most common protozoal infection in US
hallmark sign of COPD
microglia

16. Chronic gout. inhibits reabsorbtion of uric acid in PCT
probenecid
strawberry tongue
GABA - glutamine
most common bacteria in GI tract

17. Facial sensation (Make up on your face)
microglia
What thyroid pathology has an extremely tender thyroid gland
ventral posterior nucleus - medial part
brain tumor with foamy cells and high vascularity

18. Trigeminal
what nerve innervates the muscles of mastication?
cause of increased myometrial excitability
GM2 ganglioside accumulation
Conn's syndrome

19. Sulfonamides - Isonizid - Cimetidine - Ketoconazole - Erythromyicn - grapefruit juice - protease inhibitors
which nerve lifts the eyelid?
SICK PEG
parietal cells
bocks PRPP synthetase to block purine synthesis

20. Damaged in Guillian Barre
SE: elevated LFTS - myositis
most common breast tumor in women under 25
hemosiderinurea and thrombosis
schwann cells

21. Glutamate
intranuclear inclusions seen in herpes simplex encephalitis
most common primary cardiac tumor in kiddos
gram + bacteria that requires NAD and hemin for growth
precursor to GABA

22. Small diameter > large diameter; myelinated > unmyelinated
most common breast mass in pre - menopausal women
order of nerve blockade
mildly decreased UDPGT
PGI2 (prostacyclin))

23. Anxiety - seizures - delirium - life threatening CV collapse
hydatidiform mole with crazy high hCG
master clock for circadian rhythms
barbituates withdrawal
abruptio placentae

24. Bind viral gp41 subunit
antibody against philadelphia chromosome
fusion inhibitors
hydatidiform mole with crazy high hCG
vasculitis a/w Hep B

25. Increases platelet aggregation and vasoconstriction
thromboxane A2
kawasaki
most common gyno malignancy
cells destroyed in Guillain Barre

26. Obstructive - COPD
3 tumors of MEN 2a
pt has extended expiratory phase
brain tumor a/w von hipple - linadu syndrome
brain tumor with fried egg appearance

27. Dissociative
papillary thyroid cancer
adenomyosis
may lead to multiple personalities
most common first line agent for septic shock

28. Meissner
found in hairless skin
sturge weber syndrome
cause of LH surge
most common protozoal infection in US

29. Fabry's
plenta accreta
pigmented iris hamartomas - neural tumors
SICK PEG
lysosomal storage disease a/w renal disease

30. Decreased efficacy - decreased Vmax
ovarian tumor with elevate hCG
UMN signs
most common protozoal infection in US
dose response curve with noncompetitive antagonist

31. Benign - contains Reinke crystals - usually androgen producing
leydig cell tumor
nucleoside reverse transcriptase inhibitors
dermatin sulfate accumulation
t - PA - streptokinase antidote

32. Papillary CA of thyroid - meningioma - mesothelioma - serous cystadenocarcinoma of ovary
LT C4 D4 E4
psammoma bodies
anti - mitochondrial antibodies
first line for absence seizures

33. Estrogen
t - PA - streptokinase antidote
PGI2 (prostacyclin))
cause of LH surge
What hormones share a common alpha subunit

34. Ret
What oncogene is a/w MEN 2a/b
dorsal motor nucleus
Shigella
sulfonylureas

35. Placenta attached to myometrium
MofA of N- aceylcysteine
3 tumors of MEN 2a
plenta accreta
GABA - glutamine

36. Mucocutaneous lymph node syndrome - necrotizing vasculitis - coronary aneurysms - strawberry tongue
kawasaki
cells destroyed in Guillain Barre
LTB4
SE: facial flushing

37. 2 sperm + 1 egg (fetal parts present)
heparin antidote
mildly decreased UDPGT
partial mole components
ependymal cells

38. Yolk sac
locus ceruleus
pt has extended expiratory phase
sarcoma botyroides
most common testicular tumor in infants and children up to 3 years of age

39. Sulfonamides - hydralazine - isonazid - procainamide - phenytoin
drug induced lupus
probenecid
hemangioblastomas of retina/cerebellum/medulla
chromosome 4

40. Choriocarcinoma
anti - mitochondrial antibodies
cause of LH surge
tumor composed of cytotrophoblasts and syncytiotrophoblasts
plenta accreta

41. Ovarian bengin tumor...looks like bladder
basal nucleus of Meynert
brenner tumor
metformin side effect
Addison's

42. Dobutamine
11 beta hydroxylase deficiency
macrolides use (PUS)
microglia
first line for cardiogenic shock

43. Motor
VA/VL
rate limiting step in carb digestion
pt has extended expiratory phase
pigmented iris hamartomas - neural tumors

44. Seminoma
oligodendrioglia
most common testicular tumor
ovarian tumor with elevate hCG
testicular tumor that can present with gynecomastia

45. Memory
hippocampus
papillary thyroid cancer
Where does the lateral corticospinal decussate?
What thyroid pathology has an extremely tender thyroid gland

46. Auditory (Medial for Music)
blocks ADP receptors to inhibit platelet aggregation
MofA Levothyroxine
diphtheria treatment
medial geniculate nucleus

47. Membranoproliferative GN
tram - track on microscope
midshaft break of humerus
what cells secrete somatostatin
S cells

48. Inhibits platelet aggregation - promotes vasodilation and decreases uterine tone
chief cells
t - PA - streptokinase antidote
supraoptic nucleus of hypothalamus
PGI2 (prostacyclin))

49. Huntingtons chorea
testicular tumor that can present with gynecomastia
master clock for circadian rhythms
chromosome 4
ambiguous nucleus

50. Primary hyperaldosteronism (HTN - hypokalemia - metabolic alkalosis)

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USMLE Pathophys

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