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USMLE Pathophys

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Macrophages of the CNS
microglia
What are the hormone changes seen in menopause
beta glucocerebrosidase
What artery causes locked in syndrome

2. Intussception
most common breast cancer
rate limiting step in carb digestion
currant jelly stool
I cells

3. Second most common type of thyroid cancer
UMN signs
hemangioblastomas of retina/cerebellum/medulla
3 tumors of MEN 2b
follicular

4. Marfans
glycine
floppy mitral valve dissecting aortic aneurysm - berry aneurysm
failure of endodermal development
most common testicular tumor

5. Closes K+ channel on B cells causing depolarization and thus calcium influx which causes insulin release
lysosomal storage disease - demyelinating disease
sulfonylureas MofA
subluxation of lens
Lateral geniculate nucleus

6. Alpha feto protein
VA/VL
Yolk sac tumor produces...
treatment of malignant hyperthermia
abruptio placentae

7. NE
floppy mitral valve dissecting aortic aneurysm - berry aneurysm
vasculitis a/w Hep B
locus ceruleus
What artery causes locked in syndrome

8. Fabry's
order of nerve blockade
lysosomal storage disease a/w renal disease
most common first line agent for septic shock
cells destroyed in MS

9. Choriocarcinoma or dysgerminoma
mitral valve prolapse - liver diseae - berry aneurysm
ovarian tumor with elevate hCG
pigmented iris hamartomas - neural tumors
inheritance pattern for all MENs

10. Gastrin
LT C4 D4 E4
ventral posterior nucleus - lateral part
G cells
chief cells

11. Primary biliary cirrhosis
meissners
anti - mitochondrial antibodies
sulfonylureas
SICK PEG

12. Estrogen
catalase negative
Abciximab
most common breast mass in pre - menopausal women
cause of increased myometrial excitability

13. Dubin Johnson
grossly black liver
solitarius nucleus
what cells secrete somatostatin
follicular

14. Papillary
thyroid cancer associtated with RET oncogene
thromboxane A2
most common breast tumor in women under 25
Addison's

15. A few levels above the level of entry
pigmented iris hamartomas - neural tumors
ovarian tumor with elevate hCG
GFAP positive
Where does the spinothalamic decussate?

16. Incomplete fusion of processus vaginalis
pacinian
hydrocele
11 beta hydroxylase deficiency
rate limiting step in carb digestion

17. Basilar
iduronidase sulfatase
What artery causes locked in syndrome
hippocampus
hep B seropositivity in 30% of patients

18. Astrocytoma & glioblastoma multiforme
5 alpha reductase deficiency
GFAP positive
3 tumors of MEN 1
oligohydramnios

19. B. fragilis
hydatidiform mole with crazy high hCG
LTB4
most common bacteria in GI tract
brain tumor a/w von hipple - linadu syndrome

20. Oculomotor
GFAP positive
astrocytes
which nerve lifts the eyelid?
blocks ADP receptors to inhibit platelet aggregation

21. Subacute (De Quervain's) thyroiditis
plenta accreta
eczema/recurrent infections/thrombocytopenia
tram - track on microscope
What thyroid pathology has an extremely tender thyroid gland

22. Autosomal dominant
cancer associated with Hashimoto's thyroiditis
rabies
inheritance pattern for all MENs
homer wright rosettes

23. Fibroadenoma
What hormones share a common alpha subunit
keratin filled cysts
corneal clouding & MR
most common breast tumor in women under 25

24. Niemann Pick
lysosomal storage disease a/w renal disease
antibiotic with SE of eosinophilia
cells destroyed in Guillain Barre
sphingomyelinase deficiency

25. Dopamine
hemangioblastomas of retina/cerebellum/medulla
deficiency of mannose phosphorylation
MPTP exposure causes depletion of what NT?
basal nucleus of Meynert

26. Macrolides
best effect on HDL
MofA of N- aceylcysteine
cause of low pH vaginal discharge
antibiotic with SE of eosinophilia

27. Memory
sclerosing adenosis
hippocampus
child with partial albinism - peripherial neuropathy - recurrent infections
D cells

28. Hereditary spherocytosis
What causes coronary vasospasm as a SE?
placenta previa
increased MCHC and hemolytic anemia
shown to slow progression of diabetic neuropathy

29. Staph epidermidis - staph sapro
tumor with call - exner bodies
catalase positive coagulase negative
thyroid cancer associtated with RET oncogene
What causes coronary vasospasm as a SE?

30. Inflammatory lesions of subq fat - usually on anterior shins. a/w infections
found in hairless skin
ventral posterior nucleus - lateral part
erythema nodosum
drug that blocks purine synthesis and is metabolized by xanthine oxidase

31. Trichomonas - Giardia
What artery causes locked in syndrome
most common protozoal infection in US
GM2 ganglioside accumulation
eczema/recurrent infections/thrombocytopenia

32. Centriacinar
what meds treat malaria
smoking emphysema
ventral posterior nucleus - lateral part
papillary thyroid cancer

33. G1/S & G2/M
adenomyosis
deficiency of mannose phosphorylation
what nerve innervates the muscles of mastication?
what checkpoint is p53 involved with?

34. 6- MP
oligohydramnios
heparin antidote
drug that blocks purine synthesis and is metabolized by xanthine oxidase
barbituates withdrawal

35. Makes ADH
ventral posterior nucleus - lateral part
I cells
supraoptic nucleus of hypothalamus
corneal clouding & MR

36. Membranous GN
hep B seropositivity in 30% of patients
may lead to multiple personalities
spike and dome on microscope
most common breast cancer

37. TSH - LH - FSH - hCG
MofA Levothyroxine
What hormones share a common alpha subunit
alpha L iduronidase
spike and dome on microscope

38. Invasive ductal
ependymal cells
glycine
child with eczema - coarse facial features - cold abscesses
most common breast cancer

39. Weakness - atrophy - fasiculations - decreased reflexes & tone
currant jelly stool
LMN signs
dorsal motor nucleus
Conn's syndrome

40. Schwann cells
mitral valve prolapse - liver diseae - berry aneurysm
honey crusted lesions common around nose/lips
FGFR3 mutation
myelinates on PNS

41. Hurlers
preeclampsia
alpha L iduronidase
MPTP exposure causes depletion of what NT?
What are the hormone changes seen in menopause

42. Ependymoma
most common breast cancer
brain tumor with perivascular pseudorosettes
most common arrthymia
LMN signs

43. Glioblastoma multiforme
What are the hormone changes seen in menopause
inheritance pattern for all MENs
supraoptic nucleus of hypothalamus
pseudopalisading necrosis

44. Most common type of thyroid cancer
Where does the lateral corticospinal decussate?
deficiency of mannose phosphorylation
mildly decreased UDPGT
papillary thyroid cancer

45. Barbituates - carbamazapine - griseofulvin - phenytoin - quinidine - rifampin - St. John's wort
most common breast mass in pre - menopausal women
rate limiting step in carb digestion
best effect on HDL
BCG PQRS

46. Motor
most common primary cardiac tumor in kiddos
intranuclear inclusions seen in herpes simplex encephalitis
VA/VL
Yolk sac tumor produces...

47. Regenerates glutathione
MofA of N- aceylcysteine
supraoptic nucleus of hypothalamus
cancer arising from parafollicular C cells
thromboxane A2

48. H. Influenza
What are the hormone changes seen in menopause
gram + bacteria that requires NAD and hemin for growth
thymidylate synthase
precursor to GABA

49. Medulla
Where does the lateral corticospinal decussate?
branching rods on oral infection
Conn's syndrome
eczema/recurrent infections/thrombocytopenia

50. Hunters
iduronidase sulfatase
most common bacteria in GI tract
first line for absence seizures
pacinian