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USMLE Pathophys

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Bruton's agammaglobulinemia
defective tyrosine kinase
plenta accreta
rate limiting step in carb digestion
S cells

2. Chronic gout. inhibits reabsorbtion of uric acid in PCT
branching rods on oral infection
hemosiderinurea and thrombosis
probenecid
beta glucocerebrosidase

3. Medulla
whats the V/Q at the base of the lung
Abciximab
kawasaki
Where does the dorsal column decussate?

4. Subacute (De Quervain's) thyroiditis
treatment for SIADH
What thyroid pathology has an extremely tender thyroid gland
D cells
what inhibits prolactin secretion

5. Kawasaki (treat with high dose aspirin)
may lead to multiple personalities
opioid withdrawal
most common breast tumor in women under 25
strawberry tongue

6. Papillary CA of thyroid - meningioma - mesothelioma - serous cystadenocarcinoma of ovary
enzyme used to conjugate bilirubin
eczema/recurrent infections/thrombocytopenia
psammoma bodies
thromboxane A2

7. Makes ADH
plenta accreta
sumatriptan
chief cells
supraoptic nucleus of hypothalamus

8. SCID
copper - arsenic - gold antidote
looks like fried eggs under histologic staining
branching rods on oral infection
child with eczema - coarse facial features - cold abscesses

9. Cocain and sumatriptan
deficiency of mannose phosphorylation
What causes coronary vasospasm as a SE?
thromboxane A2
gram + bacteria that requires NAD and hemin for growth

10. Homocystienuria - Marfans
astrocytes
thromboxane A2
locus ceruleus
subluxation of lens

11. Babinski - weakness - increased reflexes & tone - spastic paralysis
sulfonylureas
absent UTPGT
UMN signs
myelinates multiple CNS axons

12. Protamine sulfate
H. flu
medial geniculate nucleus
heparin antidote
locus ceruleus

13. Intussception
brain tumor with foamy cells and high vascularity
currant jelly stool
treatment of malignant hyperthermia
SE: torsades de pointes

14. Damaged in multiple sclerosis
astrocytes
oligodendrioglia
cells destroyed in Guillain Barre
Bisphosphonates MofA

15. Endometrial CA
order of nerve blockade
branching rods on oral infection
most common gyno malignancy
dermatin sulfate accumulation

16. Panacinar
smoking emphysema
alpha 1 anti - trypsin
supraoptic nucleus of hypothalamus
most common first line agent for septic shock

17. Motor innervation of pharynx - larynx and upper esophagus
ambiguous nucleus
Where does the lateral corticospinal decussate?
most common gyno malignancy
chief cells

18. Inhibits viral assembly
smoking emphysema
GABA - glutamine
protease inhibitors MofA
Aschoff bodies

19. 2 sperm + empty egg (no fetal parts)
diphtheria treatment
myelinates multiple CNS axons
most common breast cancer
complete mole components

20. Auditory (Medial for Music)
3 tumors of MEN 2a
ovarian tumor with psammoma bodies
failure of endodermal development
medial geniculate nucleus

21. Vibration - pressure
SE: torsades de pointes
partial mole components
pacinian
most common gyno malignancy

22. Increases platelet aggregation and vasoconstriction
thromboxane A2
metformin side effect
most common testicular tumor in infants and children up to 3 years of age
cause of LH surge

23. Pacinian
resembles an onion in cross section
cancer arising from parafollicular C cells
smoking emphysema
most common first line agent for septic shock

24. Makes oxytocin
What artery causes locked in syndrome
paraventricular nucleus of hypothalamus
probenecid
midshaft break of humerus

25. Glioblastoma multiforme
hep B seropositivity in 30% of patients
What hormones share a common alpha subunit
chromosome 4
pseudopalisading necrosis

26. Alpha synuclein
whats the V/Q at the base of the lung
Lewy bodies composition
drug that blocks purine synthesis and is metabolized by xanthine oxidase
sulfonylureas

27. Fibrocystic
brain tumor a/w von hipple - linadu syndrome
most common breast mass in pre - menopausal women
mitral valve prolapse - liver diseae - berry aneurysm
precursor to GABA

28. Rhabdomyoma
most common primary cardiac tumor in kiddos
melanoma tumor marker
anti - epithelial antibodies
BCG PQRS

29. Anxiety - seizures - delirium - life threatening CV collapse
barbituates withdrawal
what meds treat malaria
What causes coronary vasospasm as a SE?
oligodendrioglia

30. Macconkey's agar
order of nerve blockade
Shigella
kawasaki
heparin antidote

31. Complete
iduronidase sulfatase
spike and dome on microscope
ependymal cells
hydatidiform mole with crazy high hCG

32. Penicillamine
copper - arsenic - gold antidote
follicular
antibiotic with SE of eosinophilia
eczema/recurrent infections/thrombocytopenia

33. Primary hyperaldosteronism (HTN - hypokalemia - metabolic alkalosis)

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34. Medullary thyroid - pheochromocytoma - oral/intestinal ganglionueromatosis
master clock for circadian rhythms
H. flu
3 tumors of MEN 2b
drug induced lupus

35. Wiscott - Aldrich
eczema/recurrent infections/thrombocytopenia
smoking emphysema
catalase positive coagulase negative
S cells

36. HTN - proteinuria - edema
treatment of malignant hyperthermia
what checkpoint is p53 involved with?
cells destroyed in MS
preeclampsia

37. Placenta attached to myometrium
plenta accreta
Yolk sac tumor produces...
H. flu
most common first line agent for septic shock

38. Memory
most common arrthymia
hippocampus
3 tumors of MEN 2b
thyroid cancer associtated with RET oncogene

39. Radial nerve - deep brachial artery
homer wright rosettes
What oncogene is a/w MEN 2a/b
palisading nuclei - locally invasive
midshaft break of humerus

40. Serous cystadenocarcinoma
best effect on HDL
ovarian tumor with psammoma bodies
brain tumor with foamy cells and high vascularity
most common gyno malignancy

41. ITP
most common breast tumor in women under 25
preeclampsia
pigmented iris hamartomas - neural tumors
anti - platelet antibodies

42. Primary biliary cirrhosis
pigmented iris hamartomas - neural tumors
anti - mitochondrial antibodies
neutrophils fail to respond to chemotaxic stimuli
metformin side effect

43. Imabtinib
antibody against philadelphia chromosome
rate limiting step in carb digestion
myelinates on PNS
alpha 1 anti - trypsin

44. Estrogen (causes precocious puberty)
form multinucleated giant cells in the CNS when infected with HIV
H. flu
grossly black liver
granulosa cell tumor secretes what?

45. Oligodendoglia
basal nucleus of Meynert
basal nucleus of Meynert
inheritance pattern for all MENs
myelinates multiple CNS axons

46. Sulfonamides - Isonizid - Cimetidine - Ketoconazole - Erythromyicn - grapefruit juice - protease inhibitors
cancer arising from parafollicular C cells
form multinucleated giant cells in the CNS when infected with HIV
catalase positive coagulase negative
SICK PEG

47. Hurlers
thayer martin media
catalase negative
corneal clouding & MR
infliximab

48. Vaginal carcinoma: spindle shaped tumor cells that are desmin positive
chief cells
treatment for SIADH
sarcoma botyroides
mildly decreased UDPGT

49. Decreased follicles & estrogen with increased FSH & LH
What are the hormone changes seen in menopause
copper - arsenic - gold antidote
glycine
found in hairless skin

50. Tay SaX
alpha L iduronidase
preeclampsia
heXosaminidase
hydrocele