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USMLE Pathophys

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Kawasaki (treat with high dose aspirin)
iduronidase sulfatase
chromosome 4
increased MCHC and hemolytic anemia
strawberry tongue

2. Closes K+ channel on B cells causing depolarization and thus calcium influx which causes insulin release
What hormones share a common alpha subunit
defective tyrosine kinase
pigmented iris hamartomas - neural tumors
sulfonylureas MofA

3. Facial sensation (Make up on your face)
thyroid cancer associtated with RET oncogene
ventral posterior nucleus - medial part
failure of endodermal development
antibiotic with SE of eosinophilia

4. PNH
dose response curve with noncompetitive antagonist
parietal cells
colchicine
hemosiderinurea and thrombosis

5. Function as bronchoconstrictors - vasoconstrictors - sm mm contraction and increased vascular permability
thromboxane A2
anti - epithelial antibodies
MPTP exposure causes depletion of what NT?
LT C4 D4 E4

6. Medullary
most common breast mass in pre - menopausal women
ventral posterior nucleus - lateral part
cancer arising from parafollicular C cells
antibiotic with SE of eosinophilia

7. Macrophages of the CNS
microglia
17 alpha hydroxylase deficiency
cancer arising from parafollicular C cells
vasculitis a/w Hep B

8. I- cell disease
deficiency of mannose phosphorylation
pacinian
hallmark sign of COPD
VA/VL

9. Leydig cell tumor
testicular tumor that can present with gynecomastia
barbituates withdrawal
tumor composed of cytotrophoblasts and syncytiotrophoblasts
cells destroyed in MS

10. Alpha synuclein
cause of low pH vaginal discharge
brain tumor with perivascular pseudorosettes
Lewy bodies composition
MPTP exposure causes depletion of what NT?

11. Deficiency of aldosterone and cortisol

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12. Polyarteritis nodosa
etanercept
solitarius nucleus
vasculitis a/w Hep B
Aschoff bodies

13. Gauchers
most common lysosomal storage disease
anti - epithelial antibodies
cause of increased myometrial excitability
heparin antidote

14. Yolk sac
metformin side effect
What are the hormone changes seen in menopause
most common testicular tumor in infants and children up to 3 years of age
catalase negative

15. Autosomal dominant
TZD (glitazones) MofA
5 alpha reductase deficiency
inheritance pattern for all MENs
locus ceruleus

16. S-100
melanoma tumor marker
whats the V/Q at the base of the lung
alpha 1 anti - trypsin
brain tumor with foamy cells and high vascularity

17. Staph epidermidis - staph sapro
catalase positive coagulase negative
most common arrthymia
Schiller Duval bodies
raphe nucleus

18. Polyarteritis nodosa
Schiller Duval bodies
myelinates on PNS
defective tyrosine kinase
hep B seropositivity in 30% of patients

19. Endometrial glands inside myometrium
hemosiderinurea + thrombosis
subluxation of lens
adenomyosis
thymidylate synthase

20. Ovarian bengin tumor...looks like bladder
Yolk sac tumor produces...
brenner tumor
vasculitis of infants and children - involving coronary arteries
x- linked recessive lysosomal storage diseases

21. 2 sperm + 1 egg (fetal parts present)
dorsal motor nucleus
complete mole components
partial mole components
most common breast tumor in women under 25

22. Combo of inhaled anesthetics & succinylcholine
plenta accreta
what checkpoint is p53 involved with?
cause of malignant hyperthermia
brain tumor with psammona bodies

23. Decreases conversion
PTU
astrocytes
inheritance pattern for all MENs
colchicine

24. Serotonin
thayer martin media
LTB4
raphe nucleus
ventral posterior nucleus - lateral part

25. Pemphigus vulgaris
homer wright rosettes
midshaft break of humerus
child with partial albinism - peripherial neuropathy - recurrent infections
anti - epithelial antibodies

26. H. Influenza
gram + bacteria that requires NAD and hemin for growth
Schiller Duval bodies
sulfonylureas MofA
bocks PRPP synthetase to block purine synthesis

27. Visceral sensory
P450 inducers
solitarius nucleus
kluver bucy
Addison's

28. Lactic acidosis
eczema/recurrent infections/thrombocytopenia
Aschoff bodies
pt has extended expiratory phase
metformin side effect

29. Parathyroid - pituitary - pancreatic
3 tumors of MEN 1
cause of high pH vaginal discharge
PTU
myelinates multiple CNS axons

30. Glucuronyl transferase
enzyme used to conjugate bilirubin
sphingomyelinase deficiency
midshaft break of humerus
alpha L iduronidase

31. Dubin Johnson
grossly black liver
17 alpha hydroxylase deficiency
shown to slow progression of diabetic neuropathy
treatment for SIADH

32. Incomplete fusion of processus vaginalis
brain tumor with psammona bodies
most common first line agent for septic shock
dermatin sulfate accumulation
hydrocele

33. Schwann cells
SICK PEG
alpha L iduronidase
myelinates on PNS
thromboxane A2

34. Marfans
benzos antidote
floppy mitral valve dissecting aortic aneurysm - berry aneurysm
thyroid cancer associtated with RET oncogene
hallmark sign of COPD

35. Anxiety - insomnia - sweating - dilated pupils - piloerection - rhinorrhea
brain tumor a/w von hipple - linadu syndrome
Abciximab
first line for cardiogenic shock
opioid withdrawal

36. Medullary thyroid - pheochromocytoma - oral/intestinal ganglionueromatosis
adenomyosis
follicular
3 tumors of MEN 2b
fusion inhibitors

37. Fibroadenoma
HELLP syndrome
most common breast tumor in women under 25
order of nerve blockade
Where does the dorsal column decussate?

38. Primary hyperaldosteronism (HTN - hypokalemia - metabolic alkalosis)

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39. Medulloblastoma
What thyroid pathology has an extremely tender thyroid gland
subluxation of lens
homer wright rosettes
parietal cells

40. Auditory (Medial for Music)
corneal clouding & MR
medial geniculate nucleus
antibiotic with SE of eosinophilia
crinkled paper cytoplasm

41. Granulosa cell tumor
solitarius nucleus
probenecid
tumor with call - exner bodies
I cells

42. Impetigo
What anti - hypertensive drug has the side effect of first dose orthostatic hypotension
honey crusted lesions common around nose/lips
H. flu
ventral posterior nucleus - lateral part

43. Seborric keratosis
keratin filled cysts
currant jelly stool
sclerosing adenosis
most common primary cardiac tumor in kiddos

44. Ach
GFAP positive
which nerve lifts the eyelid?
ventral posterior nucleus - lateral part
basal nucleus of Meynert

45. Bilateral renal agenesis or posterior urethral valves in males
anti - epithelial antibodies
corneal clouding & MR
brain tumor with foamy cells and high vascularity
oligohydramnios

46. Bind viral gp41 subunit
locus ceruleus
fusion inhibitors
FGFR3 mutation
S cells

47. Oligodendoglia
myelinates multiple CNS axons
vasculitis of infants and children - involving coronary arteries
optically clear nuclei (orphan annie)
increased MCHC and hemolytic anemia

48. Tay SaX
heXosaminidase
hallmark sign of COPD
thyroid cancer associtated with RET oncogene
palisading nuclei - locally invasive

49. Protamine sulfate
heparin antidote
What artery causes locked in syndrome
smoking emphysema
schwann cells

50. Cavernous hemangiomas in skin - mucosa & organs; autosomal dominant - a/w renal CA - hemangioblastoma in retina - brainstem & cerebellum
S cells
cause of high pH vaginal discharge
whats the V/Q at the apex of the lung
von Hippel Lindau disease