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USMLE Pathophys

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Invasive ductal
most common breast cancer
corneal clouding & MR
sulfonylureas side effect
MofA of N- aceylcysteine

2. Rhabdomyoma
most common primary cardiac tumor in kiddos
preeclampsia
polyhydramnios
drug that blocks purine synthesis and is metabolized by xanthine oxidase

3. Ependymoma
lysosomal storage disease a/w renal disease
absent UTPGT
brain tumor with perivascular pseudorosettes
oligodendrioglia

4. Endometrial glands inside myometrium
pigmented iris hamartomas - neural tumors
hippocampus
adenomyosis
cause of high pH vaginal discharge

5. Fibrates/statins
11 beta hydroxylase deficiency
VA/VL
what nerve innervates the muscles of mastication?
SE: elevated LFTS - myositis

6. H. Influenza
sulfonylureas MofA
gram + bacteria that requires NAD and hemin for growth
hemosiderinurea + thrombosis
Addison's

7. Meningioma
What thyroid pathology has an extremely tender thyroid gland
opioids antidote
brain tumor with psammona bodies
dose response curve change with competitive antagonist

8. Cell type involved in most ovarian tumors
thyroid cancer associtated with RET oncogene
failure of endodermal development
epithelial
chromosome 4

9. A/w esophageal/duodenal atresia and anencephaly
polyhydramnios
hippocampus
protease inhibitors MofA
locus ceruleus

10. HTN; masculinization
most common arrthymia
brain tumor with psammona bodies
11 beta hydroxylase deficiency
ovarian tumor that resembles bladder epithelium

11. Choriocarcinoma or dysgerminoma
ovarian tumor with elevate hCG
ependymal cells
blocks ADP receptors to inhibit platelet aggregation
antibody against philadelphia chromosome

12. Damaged in Guillian Barre
schwann cells
vasculitis of infants and children - involving coronary arteries
papillary thyroid cancer
medial geniculate nucleus

13. DiGeorge
failure of endodermal development
found in hairless skin
Where does the lateral corticospinal decussate?
antibody against philadelphia chromosome

14. Glutamate
midshaft break of humerus
papillary thyroid cancer
plenta accreta
precursor to GABA

15. Staph epidermidis - staph sapro
dose response curve change with competitive antagonist
Aschoff bodies
opioid withdrawal
catalase positive coagulase negative

16. Glioblastoma multiforme
pseudopalisading necrosis
Galactocerebrosidase deficiency
palisading nuclei - locally invasive
master clock for circadian rhythms

17. Decreased potency - increased Km
cells destroyed in MS
Where does the spinothalamic decussate?
dose response curve change with competitive antagonist
subluxation of lens

18. Clopidogrel - ticoplidine
lysosomal storage disease a/w renal disease
blocks ADP receptors to inhibit platelet aggregation
astrocytes
kawasaki

19. Secretin
cause of malignant hyperthermia
S cells
antibiotic with SE of eosinophilia
tram - track on microscope

20. Pepsin
ambiguous nucleus
chief cells
locus ceruleus
sclerosing adenosis

21. 6- mecaptopurine (metabolized by xanthine oxidase)
placenta previa
best effect of triglycerides/VLDL
bocks PRPP synthetase to block purine synthesis
What are the hormone changes seen in menopause

22. Seminoma
what nerve innervates the muscles of mastication?
myelinates multiple CNS axons
most common testicular tumor
erythema nodosum

23. Dantrolene (prevents release of calcium from SR of muscle)
sturge weber syndrome
treatment of malignant hyperthermia
schwann cells
etanercept

24. Babinski - weakness - increased reflexes & tone - spastic paralysis
which nerve lifts the eyelid?
pacinian
increased MCHC and hemolytic anemia
UMN signs

25. Papillary CA of thyroid
ambiguous nucleus
gram + bacteria that requires NAD and hemin for growth
optically clear nuclei (orphan annie)
most common breast tumor in women under 25

26. Papillary CA of thyroid - meningioma - mesothelioma - serous cystadenocarcinoma of ovary
most common lysosomal storage disease
follicular
psammoma bodies
What anti - hypertensive drug has the side effect of first dose orthostatic hypotension

27. Alpha feto protein
tumor composed of cytotrophoblasts and syncytiotrophoblasts
Yolk sac tumor produces...
mildly decreased UDPGT
etanercept

28. Macrophages of the CNS
alpha 1 anti - trypsin
cause of high pH vaginal discharge
brain tumor with perivascular pseudorosettes
microglia

29. Seborric keratosis
keratin filled cysts
master clock for circadian rhythms
hep B seropositivity in 30% of patients
corneal clouding & MR

30. Chediak - Higashi
locus ceruleus
child with partial albinism - peripherial neuropathy - recurrent infections
S cells
benzos antidote

31. Function as bronchoconstrictors - vasoconstrictors - sm mm contraction and increased vascular permability
paraventricular nucleus of hypothalamus
what meds treat malaria
LT C4 D4 E4
most common bacteria in GI tract

32. Fabrys
what cells secrete somatostatin
Where does the lateral corticospinal decussate?
antibiotic with SE of eosinophilia
alpha galacosidase A

33. Criglar Najar
absent UTPGT
tumor composed of cytotrophoblasts and syncytiotrophoblasts
shown to slow progression of diabetic neuropathy
Where does the dorsal column decussate?

34. Hurlers - Hunters
honey crusted lesions common around nose/lips
ventral posterior nucleus - medial part
dermatin sulfate accumulation
cancer associated with Hashimoto's thyroiditis

35. Autosomal dominant
low dose ASA effects - intermediate dose - high dose
pacinian
hemosiderinurea + thrombosis
inheritance pattern for all MENs

36. Second most common type of thyroid cancer
follicular
precursor to GABA
ovarian tumor that resembles bladder epithelium
ambiguous nucleus

37. NE
most common breast cancer
PTU
locus ceruleus
increased MCHC and hemolytic anemia

38. Obstructive - COPD
pt has extended expiratory phase
adenomyosis
follicular
SICK PEG

39. Closes K+ channel on B cells causing depolarization and thus calcium influx which causes insulin release
nucleoside reverse transcriptase inhibitors
sulfonylureas MofA
supraoptic nucleus of hypothalamus
failure of endodermal development

40. Ret
alpha galacosidase A
nucleoside reverse transcriptase inhibitors
deficiency of mannose phosphorylation
What oncogene is a/w MEN 2a/b

41. Papillary
silver stain of gram negative rods
thyroid cancer associtated with RET oncogene
propylthiouracil side effects
cells destroyed in Guillain Barre

42. Placenta attached to myometrium
dose response curve with noncompetitive antagonist
plenta accreta
antibody against philadelphia chromosome
cause of LH surge

43. Cowdry type A inclusions
PTU
benzos antidote
optically clear nuclei (orphan annie)
intranuclear inclusions seen in herpes simplex encephalitis

44. Estrogen
brenner tumor
17 alpha hydroxylase deficiency
macrolides use (PUS)
cause of LH surge

45. Motor innervation of pharynx - larynx and upper esophagus
ambiguous nucleus
basal nucleus of Meynert
BCG PQRS
heparin antidote

46. Motor
master clock for circadian rhythms
VA/VL
medial geniculate nucleus
dose response curve with noncompetitive antagonist

47. Leydig cell tumor
testicular tumor that can present with gynecomastia
ependymal cells
deficiency of mannose phosphorylation
What are the hormone changes seen in menopause

48. Facial sensation (Make up on your face)
blocks ADP receptors to inhibit platelet aggregation
leydig cell tumor
11 beta hydroxylase deficiency
ventral posterior nucleus - medial part

49. Increases platelet aggregation and vasoconstriction
MofA Levothyroxine
thromboxane A2
shown to slow progression of diabetic neuropathy
Where does the dorsal column decussate?

50. Estrogen
TZD (glitazones) MofA
myelinates multiple CNS axons
iduronidase sulfatase
cause of increased myometrial excitability