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USMLE Pathophys

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Legionella
silver stain of gram negative rods
heXosaminidase
Schiller Duval bodies
palisading nuclei - locally invasive

2. Suspensory ligament of ovaries
3 tumors of MEN 2b
tram - track on microscope
fusion inhibitors
contains ovarian vessels

3. Naloxone/naltrexone
opioids antidote
alpha L iduronidase
VA/VL
complete mole components

4. Actinomyces
Abciximab
hallmark sign of COPD
failure of endodermal development
branching rods on oral infection

5. Estrogen
optically clear nuclei (orphan annie)
ovarian tumor that resembles bladder epithelium
hemosiderinurea and thrombosis
cause of increased myometrial excitability

6. Choriocarcinoma
treatment for SIADH
dorsal motor nucleus
most common lysosomal storage disease
tumor composed of cytotrophoblasts and syncytiotrophoblasts

7. Macrophages of the CNS
ovarian tumor that resembles bladder epithelium
antibody against philadelphia chromosome
microglia
SE: facial flushing

8. Trichomonas or bacterial vaginosis
MofA Levothyroxine
neutrophils fail to respond to chemotaxic stimuli
most common arrthymia
cause of high pH vaginal discharge

9. Gauchers
diphtheria treatment
antibody against philadelphia chromosome
kluver bucy
beta glucocerebrosidase

10. Vibration - pressure
H. flu
catalase positive coagulase negative
pacinian
cause of malignant hyperthermia

11. Job's or LAD
lysosomal storage disease a/w renal disease
neutrophils fail to respond to chemotaxic stimuli
kluver bucy
most common gyno malignancy

12. Ach
dose response curve with noncompetitive antagonist
ependymal cells
basal nucleus of Meynert
PTU

13. PNH
parietal cells
low dose ASA effects - intermediate dose - high dose
which nerve lifts the eyelid?
hemosiderinurea + thrombosis

14. Invasive ductal CA
SE: elevated LFTS - myositis
most common breast mass in postmenopausal women
sarcoma botyroides
granulosa cell tumor secretes what?

15. Papillary CA of thyroid - meningioma - mesothelioma - serous cystadenocarcinoma of ovary
psammoma bodies
ventral posterior nucleus - medial part
neutrophils fail to respond to chemotaxic stimuli
G cells

16. Choriocarcinoma or dysgerminoma
propylthiouracil side effects
cancer associated with Hashimoto's thyroiditis
mildly decreased UDPGT
ovarian tumor with elevate hCG

17. Schwann cells
myelinates on PNS
Conn's syndrome
meissners
anti - platelet antibodies

18. Clopidogrel - ticoplidine
LMN signs
keratin filled cysts
blocks ADP receptors to inhibit platelet aggregation
raphe nucleus

19. DiGeorge
opioid withdrawal
spike and dome on microscope
failure of endodermal development
honey crusted lesions common around nose/lips

20. Port wine stains - ipsilateral leptomeningeal angioma; can cause glaucoma - seizures - hemipareis - and MR
meissners
lead antidote
first line for cardiogenic shock
sturge weber syndrome

21. Ethosuximide
cancer associated with Hashimoto's thyroiditis
first line for absence seizures
fusion inhibitors
H. flu

22. Normal or candida
best effect of triglycerides/VLDL
cause of low pH vaginal discharge
ovarian tumor that resembles bladder epithelium
GM2 ganglioside accumulation

23. Depolymerizes microtubules - impairing leukocyte chemotaxis and degranulation
colchicine
mildly decreased UDPGT
may lead to multiple personalities
what meds treat malaria

24. Glioblastoma multiforme
pseudopalisading necrosis
blood supply for thalamus
What thyroid pathology has an extremely tender thyroid gland
ovarian tumor with elevate hCG

25. Attachment of placenta to lower uterine segment
parietal cells
diphtheria treatment
placenta previa
what inhibits prolactin secretion

26. Meningioma
fusion inhibitors
child with partial albinism - peripherial neuropathy - recurrent infections
brain tumor with psammona bodies
found in hairless skin

27. Causes vasoconstriction (use for acute migraines)
whats the V/Q at the base of the lung
sumatriptan
GABA - glutamine
midshaft break of humerus

28. Bruton's agammaglobulinemia
diphtheria treatment
brain tumor with fried egg appearance
defective tyrosine kinase
What are the hormone changes seen in menopause

29. Hemolysis - elevated LFTs - Low Platelets
HELLP syndrome
GFAP positive
astrocytes
kluver bucy

30. Negri bodies
Shigella
shown to slow progression of diabetic neuropathy
rabies
schwann cells

31. Inhibits osteoclastic activity
Where does the spinothalamic decussate?
What thyroid pathology has an extremely tender thyroid gland
Bisphosphonates MofA
polyhydramnios

32. Aplastic anemia - rash - agranulocytosis
propylthiouracil side effects
etanercept
locus ceruleus
cells destroyed in Guillain Barre

33. Incomplete fusion of processus vaginalis
lysosomal storage disease - demyelinating disease
opioids antidote
raphe nucleus
hydrocele

34. Inner lining of ventricles - make CSF - originate from neuroectoderm
inheritance pattern for all MENs
x- linked recessive lysosomal storage diseases
ependymal cells
G cells

35. HTN - proteinuria - edema
parietal cells
GFAP positive
preeclampsia
hep B seropositivity in 30% of patients

36. Kawasaki (treat with high dose aspirin)
macrolides use (PUS)
fusion inhibitors
strawberry tongue
thyroid cancer associtated with RET oncogene

37. Ependymoma
FGFR3 mutation
brain tumor with perivascular pseudorosettes
LMN signs
what cells secrete somatostatin

38. Pacinian
most common bacteria in GI tract
resembles an onion in cross section
looks like fried eggs under histologic staining
testicular tumor that can present with gynecomastia

39. Neutrophil chemotactic agent 'neutrophils arrive B4 others'
heparin antidote
LTB4
Galactocerebrosidase deficiency
most common breast mass in pre - menopausal women

40. Inhibits viral assembly
brain tumor with foamy cells and high vascularity
infliximab
protease inhibitors MofA
anti - epithelial antibodies

41. Increases platelet aggregation and vasoconstriction
tumor composed of cytotrophoblasts and syncytiotrophoblasts
neutrophils fail to respond to chemotaxic stimuli
thromboxane A2
sulfonylureas side effect

42. Penicillamine
honey crusted lesions common around nose/lips
hallmark sign of COPD
alpha 1 anti - trypsin
copper - arsenic - gold antidote

43. Inhibitory in the SC
child with partial albinism - peripherial neuropathy - recurrent infections
ventral posterior nucleus - medial part
ovarian tumor that resembles bladder epithelium
glycine

44. Meissner
whats the V/Q at the apex of the lung
basal nucleus of Meynert
found in hairless skin
parietal cells

45. Obstructive - COPD
blocks ADP receptors to inhibit platelet aggregation
pt has extended expiratory phase
floppy mitral valve dissecting aortic aneurysm - berry aneurysm
what inhibits prolactin secretion

46. 3
whats the V/Q at the apex of the lung
bocks PRPP synthetase to block purine synthesis
treatment for SIADH
hallmark sign of COPD

47. NE
locus ceruleus
sulfonylureas MofA
solitarius nucleus
cause of LH surge

48. Impetigo
honey crusted lesions common around nose/lips
anti - epithelial antibodies
GABA - glutamine
P450 Inhibitors

49. Anxiety - seizures - delirium - life threatening CV collapse
heparin antidote
3 tumors of MEN 2a
barbituates withdrawal
cough - conjunctivitis - coryza - fever

50. 6- MP
blocks ADP receptors to inhibit platelet aggregation
best effect on HDL
cause of high pH vaginal discharge
drug that blocks purine synthesis and is metabolized by xanthine oxidase