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USMLE Pathophys

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. HTN; masculinization
probenecid
what checkpoint is p53 involved with?
most common bacteria in GI tract
11 beta hydroxylase deficiency

2. Deficiency of aldosterone and cortisol

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3. Second most common type of thyroid cancer
Where does the lateral corticospinal decussate?
follicular
cells destroyed in Guillain Barre
kluver bucy

4. Inner lining of ventricles - make CSF - originate from neuroectoderm
most common testicular tumor
ependymal cells
basal nucleus of Meynert
cells destroyed in Guillain Barre

5. Krabbe's
sturge weber syndrome
Galactocerebrosidase deficiency
catalase negative
resembles an onion in cross section

6. Body sensation
antibody against philadelphia chromosome
ventral posterior nucleus - lateral part
glycine
most common breast cancer

7. Homocystienuria - Marfans
cough - conjunctivitis - coryza - fever
subluxation of lens
brain tumor a/w von hipple - linadu syndrome
nucleoside reverse transcriptase inhibitors

8. Ovarian bengin tumor...looks like bladder
intranuclear inclusions seen in herpes simplex encephalitis
sarcoma botyroides
Lateral geniculate nucleus
brenner tumor

9. Hereditary spherocytosis
increased MCHC and hemolytic anemia
dorsal motor nucleus
hydatidiform mole with crazy high hCG
iduronidase sulfatase

10. Job's or LAD
dose response curve change with competitive antagonist
neutrophils fail to respond to chemotaxic stimuli
whats the V/Q at the base of the lung
complete mole components

11. Aminocaproic acid
leydig cell tumor
cause of high pH vaginal discharge
Bisphosphonates MofA
t - PA - streptokinase antidote

12. Visceral sensory
LMN signs
midshaft break of humerus
cells destroyed in Guillain Barre
solitarius nucleus

13. Impetigo
increased MCHC and hemolytic anemia
honey crusted lesions common around nose/lips
nucleoside reverse transcriptase inhibitors
sarcoma botyroides

14. Naloxone/naltrexone
palisading nuclei - locally invasive
placenta previa
opioids antidote
medial geniculate nucleus

15. DiGeorge
failure of endodermal development
follicular
order of nerve blockade
UMN signs

16. Seborric keratosis
dermatin sulfate accumulation
defective tyrosine kinase
P450 Inhibitors
keratin filled cysts

17. Makes ADH
supraoptic nucleus of hypothalamus
floppy mitral valve dissecting aortic aneurysm - berry aneurysm
first line for absence seizures
epithelial

18. Oculomotor
thyroid cancer associtated with RET oncogene
which nerve lifts the eyelid?
lysosomal storage disease a/w renal disease
solitarius nucleus

19. Invasive ductal
drug induced lupus
ambiguous nucleus
preeclampsia
most common breast cancer

20. BCG PQRS
sarcoma botyroides
blocks ADP receptors to inhibit platelet aggregation
glycine
P450 inducers

21. Actinomyces
floppy mitral valve dissecting aortic aneurysm - berry aneurysm
MofA Levothyroxine
branching rods on oral infection
SE: elevated LFTS - myositis

22. Facial sensation (Make up on your face)
myelinates on PNS
lysosomal storage disease - demyelinating disease
ventral posterior nucleus - medial part
most common breast mass in postmenopausal women

23. Polyarteritis nodosa
hep B seropositivity in 30% of patients
dose response curve with noncompetitive antagonist
microglia
alpha L iduronidase

24. Placenta attached to myometrium
plenta accreta
kawasaki
hemosiderinurea and thrombosis
cause of increased myometrial excitability

25. Oligosaccaride hydrolase
hippocampus
partial mole components
defective tyrosine kinase
rate limiting step in carb digestion

26. Macrophages of the CNS
microglia
cause of low pH vaginal discharge
complete mole components
what nerve innervates the muscles of mastication?

27. Von Hippel Lindau
sarcoma botyroides
resembles an onion in cross section
hemangioblastomas of retina/cerebellum/medulla
precursor to GABA

28. Membranous GN
pseudopalisading necrosis
spike and dome on microscope
Lateral geniculate nucleus
17 alpha hydroxylase deficiency

29. Ach
kluver bucy
most common primary cardiac tumor in kiddos
HELLP syndrome
basal nucleus of Meynert

30. Intrinsic factor
whats the V/Q at the apex of the lung
epithelial
defective tyrosine kinase
parietal cells

31. Auditory (Medial for Music)
D cells
medial geniculate nucleus
copper - arsenic - gold antidote
oligohydramnios

32. Gastrin
Where does the lateral corticospinal decussate?
kawasaki
G cells
tumor with call - exner bodies

33. Prazosin
dermatin sulfate accumulation
placenta previa
optically clear nuclei (orphan annie)
What anti - hypertensive drug has the side effect of first dose orthostatic hypotension

34. Ret
MPTP exposure causes depletion of what NT?
oligohydramnios
What oncogene is a/w MEN 2a/b
Lewy bodies composition

35. Decreased FEV/FVC ratio
currant jelly stool
infliximab
propylthiouracil side effects
hallmark sign of COPD

36. Ethosuximide
first line for absence seizures
What causes coronary vasospasm as a SE?
leydig cell tumor
3 tumors of MEN 2a

37. Meissner
found in hairless skin
partial mole components
TZD (glitazones) MofA
Lateral geniculate nucleus

38. Prevents incorporation into host DNA
locus ceruleus
nucleoside reverse transcriptase inhibitors
benzos antidote
Lewy bodies composition

39. Flumazenil
benzos antidote
ventral posterior nucleus - medial part
Conn's syndrome
H. flu

40. Cause release of preformed insulin
sulfonylureas
shown to slow progression of diabetic neuropathy
medial geniculate nucleus
lead antidote

41. Somatostatin
barbituates withdrawal
D cells
cause of high pH vaginal discharge
best effect on HDL

42. Yolk sac tumor
nucleoside reverse transcriptase inhibitors
LMN signs
Schiller Duval bodies
3 tumors of MEN 2a

43. Brenners tumor
anti - platelet antibodies
P450 Inhibitors
ovarian tumor that resembles bladder epithelium
Aschoff bodies

44. Lactic acidosis
PTU
metformin side effect
pseudopalisading necrosis
sphingomyelinase deficiency

45. Gauchers
antibody against philadelphia chromosome
partial mole components
papillary thyroid cancer
beta glucocerebrosidase

46. Inhibits platelet aggregation - promotes vasodilation and decreases uterine tone
astrocytes
heXosaminidase
PGI2 (prostacyclin))
sulfonylureas MofA

47. Normal or candida
colchicine
cause of low pH vaginal discharge
honey crusted lesions common around nose/lips
smoking emphysema

48. Chloroquine and primaquine
most common arrthymia
P450 Inhibitors
SE: facial flushing
what meds treat malaria

49. 2 sperm + empty egg (no fetal parts)
What are the hormone changes seen in menopause
complete mole components
3 tumors of MEN 2b
hydrocele

50. Fibrates/statins
keratin filled cysts
treatment of malignant hyperthermia
SE: elevated LFTS - myositis
P450 Inhibitors