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USMLE Pathophys

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. 6- mecaptopurine (metabolized by xanthine oxidase)
silver stain of gram negative rods
lisch nodules
bocks PRPP synthetase to block purine synthesis
sturge weber syndrome

2. Job's or LAD
ovarian tumor with psammoma bodies
P450 Inhibitors
dorsal motor nucleus
neutrophils fail to respond to chemotaxic stimuli

3. Ret
hydatidiform mole with crazy high hCG
may lead to multiple personalities
What oncogene is a/w MEN 2a/b
von Hippel Lindau disease

4. Oligosaccaride hydrolase
macrolides use (PUS)
drug that blocks purine synthesis and is metabolized by xanthine oxidase
raphe nucleus
rate limiting step in carb digestion

5. A few levels above the level of entry
most common lysosomal storage disease
Where does the spinothalamic decussate?
contains ovarian vessels
HELLP syndrome

6. Secretin
S cells
catalase positive coagulase negative
most common gyno malignancy
cells destroyed in Guillain Barre

7. Actinomyces
tram - track on microscope
lysosomal storage disease a/w renal disease
ventral posterior nucleus - medial part
branching rods on oral infection

8. Serotonin
found in hairless skin
raphe nucleus
smoking emphysema
deficiency of mannose phosphorylation

9. Achondroplasia
colchicine
ovarian tumor with elevate hCG
Bisphosphonates MofA
FGFR3 mutation

10. Granulosa cell tumor
preeclampsia
thayer martin media
most common testicular tumor
tumor with call - exner bodies

11. Lymphoma

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12. Macconkey's agar
vasculitis of infants and children - involving coronary arteries
diphtheria treatment
Shigella
midshaft break of humerus

13. Decreases conversion
what cells secrete somatostatin
pigmented iris hamartomas - neural tumors
PTU
supraoptic nucleus of hypothalamus

14. Memory
intranuclear inclusions seen in herpes simplex encephalitis
What anti - hypertensive drug has the side effect of first dose orthostatic hypotension
dose response curve with noncompetitive antagonist
hippocampus

15. Medullary thyroid - pheochromocytoma - oral/intestinal ganglionueromatosis
pseudopalisading necrosis
cause of high pH vaginal discharge
3 tumors of MEN 2b
antibody against philadelphia chromosome

16. Makes oxytocin
Lateral geniculate nucleus
paraventricular nucleus of hypothalamus
hemosiderinurea + thrombosis
Where does the dorsal column decussate?

17. Hairless skin - dynamic fine touch
grossly black liver
meissners
most common breast tumor in women under 25
currant jelly stool

18. Posterior communicating - posterior cerebral - anterior choroidal arteries
cough - conjunctivitis - coryza - fever
most common breast tumor in women under 25
blood supply for thalamus
hydrocele

19. Gauchers
hemosiderinurea + thrombosis
pseudopalisading necrosis
crinkled paper cytoplasm
brenner tumor

20. Medulloblastoma
homer wright rosettes
rabies
hemosiderinurea + thrombosis
supraoptic nucleus of hypothalamus

21. Yolk sac tumor
Schiller Duval bodies
sphingomyelinase deficiency
leydig cell tumor
Lewy bodies composition

22. B. fragilis
treatment of malignant hyperthermia
lead antidote
mitral valve prolapse - liver diseae - berry aneurysm
most common bacteria in GI tract

23. Ach
supraoptic nucleus of hypothalamus
basal nucleus of Meynert
lewy body composition
eczema/recurrent infections/thrombocytopenia

24. Hurlers - Hunters
dermatin sulfate accumulation
Lateral geniculate nucleus
Shigella
best effect of triglycerides/VLDL

25. Basal cell carcinoma
TZD (glitazones) MofA
most common gyno malignancy
palisading nuclei - locally invasive
sturge weber syndrome

26. Oligodendroglia
looks like fried eggs under histologic staining
cause of increased myometrial excitability
ambiguous nucleus
LTB4

27. Niacin
low dose ASA effects - intermediate dose - high dose
nucleoside reverse transcriptase inhibitors
SE: facial flushing
3 tumors of MEN 2a

28. Antibody binds to gp2b/3a - preventing aggregation
Abciximab
I cells
solitarius nucleus
polyhydramnios

29. Leydig cell tumor
most common primary cardiac tumor in kiddos
smoking emphysema
what inhibits prolactin secretion
testicular tumor that can present with gynecomastia

30. Medulla
corneal clouding & MR
Where does the lateral corticospinal decussate?
tram - track on microscope
cough - conjunctivitis - coryza - fever

31. Bruton's agammaglobulinemia
strawberry tongue
defective tyrosine kinase
most common bacteria in GI tract
bocks PRPP synthetase to block purine synthesis

32. Hypoglycemia
heparin antidote
dose response curve change with competitive antagonist
sulfonylureas side effect
colchicine

33. Attachment of placenta to lower uterine segment
deficiency of mannose phosphorylation
placenta previa
cancer arising from parafollicular C cells
schwann cells

34. Bind viral gp41 subunit
11 beta hydroxylase deficiency
fusion inhibitors
may lead to multiple personalities
tram - track on microscope

35. Seborric keratosis
what meds treat malaria
most common primary cardiac tumor in kiddos
sarcoma botyroides
keratin filled cysts

36. Small diameter > large diameter; myelinated > unmyelinated
17 alpha hydroxylase deficiency
papillary thyroid cancer
most common breast tumor in women under 25
order of nerve blockade

37. I- cell disease
What are the hormone changes seen in menopause
deficiency of mannose phosphorylation
schwann cells
5 alpha reductase deficiency

38. Actinomyces
kawasaki
branching rods on oral infection
catalase positive coagulase negative
what cells secrete somatostatin

39. PPAR- gamma receptor agonist - which causes improved target cell response to insulin
metformin side effect
mitral valve prolapse - liver diseae - berry aneurysm
TZD (glitazones) MofA
papillary thyroid cancer

40. PNH
form multinucleated giant cells in the CNS when infected with HIV
hemosiderinurea + thrombosis
heXosaminidase
G cells

41. Body sensation
what checkpoint is p53 involved with?
hydrocele
von Hippel Lindau disease
ventral posterior nucleus - lateral part

42. Ethosuximide
child with partial albinism - peripherial neuropathy - recurrent infections
UMN signs
hydatidiform mole with crazy high hCG
first line for absence seizures

43. Chloroquine and primaquine
tumor composed of cytotrophoblasts and syncytiotrophoblasts
tram - track on microscope
what meds treat malaria
branching rods on oral infection

44. Superchiasmic nucleus
meissners
Lateral geniculate nucleus
master clock for circadian rhythms
S cells

45. Oligodendrogila
best effect of triglycerides/VLDL
SICK PEG
cells destroyed in MS
17 alpha hydroxylase deficiency

46. Penicillamine
copper - arsenic - gold antidote
ovarian tumor with psammoma bodies
SICK PEG
floppy mitral valve dissecting aortic aneurysm - berry aneurysm

47. Pepsin
G cells
drug induced lupus
chief cells
Lateral geniculate nucleus

48. Pneumonia - URIs - STDS
sarcoma botyroides
grossly black liver
macrolides use (PUS)
GM2 ganglioside accumulation

49. Gastrin
blood supply for thalamus
macrolides use (PUS)
G cells
enzyme used to conjugate bilirubin

50. Endometrial CA
papillary thyroid cancer
Where does the dorsal column decussate?
what checkpoint is p53 involved with?
most common gyno malignancy