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USMLE Pathophys

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Primary hyperaldosteronism (HTN - hypokalemia - metabolic alkalosis)

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2. Dissociative
may lead to multiple personalities
lysosomal storage disease - demyelinating disease
locus ceruleus
SE: facial flushing

3. Niacin
SE: facial flushing
sphingomyelinase deficiency
schwann cells
sulfonylureas side effect

4. Trigeminal
beta glucocerebrosidase
BCG PQRS
psammoma bodies
what nerve innervates the muscles of mastication?

5. Seminoma
sulfonylureas MofA
most common testicular tumor
etanercept
cause of low pH vaginal discharge

6. Fabry's
antibiotic with SE of eosinophilia
chromosome 4
lysosomal storage disease a/w renal disease
17 alpha hydroxylase deficiency

7. Endometrial CA
What artery causes locked in syndrome
heparin antidote
most common gyno malignancy
Yolk sac tumor produces...

8. Gauchers
most common lysosomal storage disease
most common primary cardiac tumor in kiddos
fusion inhibitors
D cells

9. Sotalol - quinidine - cisapride
SE: torsades de pointes
LMN signs
smoking emphysema
cause of LH surge

10. Inner lining of ventricles - make CSF - originate from neuroectoderm
paraventricular nucleus of hypothalamus
ependymal cells
may lead to multiple personalities
polyhydramnios

11. Oligodendroglia
anti - mitochondrial antibodies
Aschoff bodies
deficiency of mannose phosphorylation
looks like fried eggs under histologic staining

12. Hereditary spherocytosis
etanercept
What thyroid pathology has an extremely tender thyroid gland
most common testicular tumor
increased MCHC and hemolytic anemia

13. Trichomonas or bacterial vaginosis
branching rods on oral infection
cause of high pH vaginal discharge
intranuclear inclusions seen in herpes simplex encephalitis
opioid withdrawal

14. Ovarian bengin tumor...looks like bladder
sarcoma botyroides
schwann cells
leydig cell tumor
brenner tumor

15. Oculomotor
oligodendrioglia
which nerve lifts the eyelid?
lead antidote
psammoma bodies

16. Leydig cell tumor
testicular tumor that can present with gynecomastia
papillary thyroid cancer
What thyroid pathology has an extremely tender thyroid gland
anti - platelet antibodies

17. Oligosaccaride hydrolase
defective tyrosine kinase
kluver bucy
rate limiting step in carb digestion
I cells

18. Radial nerve - deep brachial artery
midshaft break of humerus
oligodendrioglia
macrolides use (PUS)
TZD (glitazones) MofA

19. Krabbe's
treatment of malignant hyperthermia
polyhydramnios
iduronidase sulfatase
Galactocerebrosidase deficiency

20. Inhibits viral assembly
increased MCHC and hemolytic anemia
etanercept
currant jelly stool
protease inhibitors MofA

21. Ret
MPTP exposure causes depletion of what NT?
cancer associated with Hashimoto's thyroiditis
child with eczema - coarse facial features - cold abscesses
What oncogene is a/w MEN 2a/b

22. Attachment of placenta to lower uterine segment
dose response curve change with competitive antagonist
SE: elevated LFTS - myositis
placenta previa
Lateral geniculate nucleus

23. Premature detachment of placenta - painful bleeding in 3rd trimester
dose response curve with noncompetitive antagonist
anti - epithelial antibodies
cause of low pH vaginal discharge
abruptio placentae

24. Intrinsic factor
mildly decreased UDPGT
testicular tumor that can present with gynecomastia
parietal cells
chief cells

25. Bromocriptine
what inhibits prolactin secretion
leydig cell tumor
most common arrthymia
dose response curve change with competitive antagonist

26. Normal or candida
catalase positive coagulase negative
cause of low pH vaginal discharge
raphe nucleus
ventral posterior nucleus - medial part

27. Choriocarcinoma
tumor composed of cytotrophoblasts and syncytiotrophoblasts
enzyme used to conjugate bilirubin
ambiguous nucleus
Schiller Duval bodies

28. Motor
glycine
blocks ADP receptors to inhibit platelet aggregation
failure of endodermal development
VA/VL

29. ITP
anti - platelet antibodies
looks like fried eggs under histologic staining
melanoma tumor marker
S cells

30. Alpha synuclein
neutrophils fail to respond to chemotaxic stimuli
Lewy bodies composition
anti - platelet antibodies
sulfonylureas MofA

31. Body sensation
metformin side effect
solitarius nucleus
papillary thyroid cancer
ventral posterior nucleus - lateral part

32. H. Influenza
gram + bacteria that requires NAD and hemin for growth
mildly decreased UDPGT
abruptio placentae
x- linked recessive lysosomal storage diseases

33. Bruton's agammaglobulinemia
defective tyrosine kinase
what checkpoint is p53 involved with?
smoking emphysema
diphtheria treatment

34. Dantrolene (prevents release of calcium from SR of muscle)
GM2 ganglioside accumulation
treatment of malignant hyperthermia
infliximab
placenta previa

35. Aminocaproic acid
master clock for circadian rhythms
17 alpha hydroxylase deficiency
t - PA - streptokinase antidote
kawasaki

36. Kawasaki
vasculitis of infants and children - involving coronary arteries
preeclampsia
most common breast mass in postmenopausal women
fusion inhibitors

37. Hurlers
honey crusted lesions common around nose/lips
basal nucleus of Meynert
alpha L iduronidase
child with eczema - coarse facial features - cold abscesses

38. A/w esophageal/duodenal atresia and anencephaly
polyhydramnios
hydatidiform mole with crazy high hCG
branching rods on oral infection
anti - platelet antibodies

39. I- cell disease
LTB4
deficiency of mannose phosphorylation
nucleoside reverse transcriptase inhibitors
hemangioblastomas of retina/cerebellum/medulla

40. Alpha feto protein
Yolk sac tumor produces...
what meds treat malaria
most common lysosomal storage disease
parietal cells

41. Cause release of preformed insulin
ventral posterior nucleus - lateral part
brain tumor with foamy cells and high vascularity
bocks PRPP synthetase to block purine synthesis
sulfonylureas

42. NE
optically clear nuclei (orphan annie)
raphe nucleus
most common breast cancer
most common first line agent for septic shock

43. Damaged in multiple sclerosis
oligodendrioglia
placenta previa
thromboxane A2
cause of LH surge

44. Measles
anti - platelet antibodies
cough - conjunctivitis - coryza - fever
17 alpha hydroxylase deficiency
dermatin sulfate accumulation

45. Posterior communicating - posterior cerebral - anterior choroidal arteries
form multinucleated giant cells in the CNS when infected with HIV
ventral posterior nucleus - lateral part
blood supply for thalamus
grossly black liver

46. Niacins
best effect on HDL
Where does the spinothalamic decussate?
preeclampsia
What thyroid pathology has an extremely tender thyroid gland

47. Oligodendrogila
hemosiderinurea and thrombosis
SE: facial flushing
D cells
cells destroyed in MS

48. Inhibitory in the SC
cancer arising from parafollicular C cells
glycine
benzos antidote
protease inhibitors MofA

49. Microglia
form multinucleated giant cells in the CNS when infected with HIV
vasculitis of infants and children - involving coronary arteries
lisch nodules
diphtheria treatment

50. NE
child with eczema - coarse facial features - cold abscesses
master clock for circadian rhythms
locus ceruleus
astrocytes