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USMLE Pathophys

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Damaged in Guillian Barre
anti - platelet antibodies
What oncogene is a/w MEN 2a/b
GABA - glutamine
schwann cells

2. Visceral sensory
resembles an onion in cross section
What hormones share a common alpha subunit
solitarius nucleus
propylthiouracil side effects

3. Hemangioblastoma
epithelial
brain tumor with foamy cells and high vascularity
alpha 1 anti - trypsin
vasculitis a/w Hep B

4. Prevents incorporation into host DNA
nucleoside reverse transcriptase inhibitors
cause of high pH vaginal discharge
strawberry tongue
hippocampus

5. Neutrophil chemotactic agent 'neutrophils arrive B4 others'
UMN signs
sulfonylureas
LTB4
D cells

6. Seborric keratosis
keratin filled cysts
papillary thyroid cancer
solitarius nucleus
bocks PRPP synthetase to block purine synthesis

7. Chocolate agar
metformin side effect
antibody against philadelphia chromosome
H. flu
vasculitis a/w Hep B

8. Dantrolene (prevents release of calcium from SR of muscle)
sarcoma botyroides
treatment of malignant hyperthermia
most common lysosomal storage disease
lewy body composition

9. Mucocutaneous lymph node syndrome - necrotizing vasculitis - coronary aneurysms - strawberry tongue
kawasaki
sulfonylureas
blood supply for thalamus
lewy body composition

10. Decreased follicles & estrogen with increased FSH & LH
thyroid cancer associtated with RET oncogene
infliximab
3 tumors of MEN 2b
What are the hormone changes seen in menopause

11. Flumazenil
tram - track on microscope
benzos antidote
rabies
What artery causes locked in syndrome

12. Medullary
cancer arising from parafollicular C cells
Yolk sac tumor produces...
probenecid
neutrophils fail to respond to chemotaxic stimuli

13. Negri bodies
heparin antidote
rabies
propylthiouracil side effects
honey crusted lesions common around nose/lips

14. Hemolysis - elevated LFTs - Low Platelets
copper - arsenic - gold antidote
palisading nuclei - locally invasive
HELLP syndrome
cancer arising from parafollicular C cells

15. Gilberts
alpha galacosidase A
P450 Inhibitors
most common bacteria in GI tract
mildly decreased UDPGT

16. Ret
abruptio placentae
What oncogene is a/w MEN 2a/b
heXosaminidase
alpha L iduronidase

17. Visual (Lateral for Light)
copper - arsenic - gold antidote
Lateral geniculate nucleus
anti - platelet antibodies
What are the hormone changes seen in menopause

18. HTN; masculinization
solitarius nucleus
11 beta hydroxylase deficiency
ventral posterior nucleus - medial part
Lewy bodies composition

19. Measles
cough - conjunctivitis - coryza - fever
resembles an onion in cross section
cells destroyed in MS
keratin filled cysts

20. Hurlers - Hunters
dermatin sulfate accumulation
most common testicular tumor
contains ovarian vessels
most common bacteria in GI tract

21. Hemangioblastoma
What are the hormone changes seen in menopause
Abciximab
brain tumor a/w von hipple - linadu syndrome
dose response curve with noncompetitive antagonist

22. Dopamine
ventral posterior nucleus - lateral part
brain tumor with psammona bodies
MPTP exposure causes depletion of what NT?
tumor with call - exner bodies

23. 2 sperm + empty egg (no fetal parts)
most common breast cancer
LT C4 D4 E4
lisch nodules
complete mole components

24. DiGeorge
blocks ADP receptors to inhibit platelet aggregation
failure of endodermal development
opioids antidote
most common breast tumor in women under 25

25. Premature detachment of placenta - painful bleeding in 3rd trimester
shown to slow progression of diabetic neuropathy
abruptio placentae
raphe nucleus
metformin side effect

26. Macconkey's agar
first line for absence seizures
What oncogene is a/w MEN 2a/b
what checkpoint is p53 involved with?
Shigella

27. Parathyroid - pituitary - pancreatic
von Hippel Lindau disease
3 tumors of MEN 1
H. flu
microglia

28. Decreased FEV/FVC ratio
mitral valve prolapse - liver diseae - berry aneurysm
hallmark sign of COPD
copper - arsenic - gold antidote
dorsal motor nucleus

29. Trichomonas or bacterial vaginosis
alpha 1 anti - trypsin
cause of high pH vaginal discharge
fusion inhibitors
heparin antidote

30. Small diameter > large diameter; myelinated > unmyelinated
cause of malignant hyperthermia
antibody against philadelphia chromosome
order of nerve blockade
thromboxane A2

31. Macrophages of the CNS
optically clear nuclei (orphan annie)
G cells
Shigella
microglia

32. Complete
What causes coronary vasospasm as a SE?
hydatidiform mole with crazy high hCG
cause of malignant hyperthermia
which nerve lifts the eyelid?

33. Superchiasmic nucleus
epithelial
probenecid
master clock for circadian rhythms
floppy mitral valve dissecting aortic aneurysm - berry aneurysm

34. Serotonin
P450 inducers
raphe nucleus
first line for cardiogenic shock
smoking emphysema

35. Polyarteritis nodosa
hep B seropositivity in 30% of patients
keratin filled cysts
sulfonylureas
first line for cardiogenic shock

36. Inhibits viral assembly
protease inhibitors MofA
Conn's syndrome
21 hydroxylase deficiency
FGFR3 mutation

37. Glioblastoma multiforme
pseudopalisading necrosis
Shigella
child with partial albinism - peripherial neuropathy - recurrent infections
hep B seropositivity in 30% of patients

38. Antitoxin - penicillin - DPT vaccine
diphtheria treatment
most common primary cardiac tumor in kiddos
fusion inhibitors
melanoma tumor marker

39. Masculinization - hypovolemic shock
most common breast mass in pre - menopausal women
21 hydroxylase deficiency
blood supply for thalamus
most common gyno malignancy

40. Cocain and sumatriptan
optically clear nuclei (orphan annie)
lysosomal storage disease - demyelinating disease
FGFR3 mutation
What causes coronary vasospasm as a SE?

41. Niacin
SE: facial flushing
placenta previa
follicular
alpha 1 anti - trypsin

42. Penicillamine
vasculitis a/w Hep B
copper - arsenic - gold antidote
blocks ADP receptors to inhibit platelet aggregation
keratin filled cysts

43. Aplastic anemia - rash - agranulocytosis
thyroid cancer associtated with RET oncogene
myelinates multiple CNS axons
propylthiouracil side effects
H. flu

44. Choriocarcinoma
paraventricular nucleus of hypothalamus
sulfonylureas MofA
tumor composed of cytotrophoblasts and syncytiotrophoblasts
pseudopalisading necrosis

45. Gastrin
rabies
lead antidote
G cells
leydig cell tumor

46. Vibration - pressure
H. flu
Where does the spinothalamic decussate?
pacinian
GFAP positive

47. Motor
VA/VL
S cells
whats the V/Q at the apex of the lung
TZD (glitazones) MofA

48. 5- fluorouracil
pacinian
basal nucleus of Meynert
thymidylate synthase
metformin side effect

49. Decreases conversion
Conn's syndrome
PTU
sclerosing adenosis
thymidylate synthase

50. Ach
order of nerve blockade
rabies
basal nucleus of Meynert
alpha 1 anti - trypsin