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USMLE Pathophys

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Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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1. Obstructive - COPD
hemosiderinurea + thrombosis
pt has extended expiratory phase
3 tumors of MEN 2b
most common first line agent for septic shock

2. Impetigo
order of nerve blockade
H. flu
hydrocele
honey crusted lesions common around nose/lips

3. Decreases conversion
Where does the spinothalamic decussate?
supraoptic nucleus of hypothalamus
grossly black liver
PTU

4. Fabry's
PGI2 (prostacyclin))
MofA of N- aceylcysteine
epithelial
lysosomal storage disease a/w renal disease

5. Cell type involved in most ovarian tumors
spike and dome on microscope
preeclampsia
epithelial
GABA - glutamine

6. Clopidogrel - ticoplidine
blocks ADP receptors to inhibit platelet aggregation
sulfonylureas MofA
pacinian
S cells

7. Kawasaki
vasculitis of infants and children - involving coronary arteries
schwann cells
what inhibits prolactin secretion
parietal cells

8. Bruton's agammaglobulinemia
myelinates on PNS
defective tyrosine kinase
lysosomal storage disease a/w renal disease
drug induced lupus

9. Cant convert testosterone to DHT - ambiguous genitalia until puberty then penis at 12
dermatin sulfate accumulation
first line for cardiogenic shock
alpha galacosidase A
5 alpha reductase deficiency

10. Schwann cells
cells destroyed in Guillain Barre
glycine
most common breast cancer
Where does the lateral corticospinal decussate?

11. Decreased follicles & estrogen with increased FSH & LH
heparin antidote
What are the hormone changes seen in menopause
hemosiderinurea and thrombosis
antibody against philadelphia chromosome

12. Niemann Pick
MofA Levothyroxine
brain tumor with psammona bodies
hemangioblastomas of retina/cerebellum/medulla
sphingomyelinase deficiency

13. Placenta attached to myometrium
etanercept
plenta accreta
bocks PRPP synthetase to block purine synthesis
dose response curve change with competitive antagonist

14. Trichomonas or bacterial vaginosis
etanercept
most common arrthymia
sarcoma botyroides
cause of high pH vaginal discharge

15. Posterior communicating - posterior cerebral - anterior choroidal arteries
catalase negative
whats the V/Q at the apex of the lung
midshaft break of humerus
blood supply for thalamus

16. Fabrys
inheritance pattern for all MENs
failure of endodermal development
hemosiderinurea + thrombosis
alpha galacosidase A

17. Benign - contains Reinke crystals - usually androgen producing
fusion inhibitors
most common bacteria in GI tract
leydig cell tumor
SE: facial flushing

18. Aminocaproic acid
hallmark sign of COPD
P450 Inhibitors
t - PA - streptokinase antidote
mitral valve prolapse - liver diseae - berry aneurysm

19. Marfans
absent UTPGT
treatment of malignant hyperthermia
TZD (glitazones) MofA
floppy mitral valve dissecting aortic aneurysm - berry aneurysm

20. Sulfonamides - Isonizid - Cimetidine - Ketoconazole - Erythromyicn - grapefruit juice - protease inhibitors
most common breast tumor in women under 25
SICK PEG
lead antidote
GFAP positive

21. Papillary CA of thyroid
optically clear nuclei (orphan annie)
erythema nodosum
ovarian tumor with elevate hCG
Where does the lateral corticospinal decussate?

22. Hemangioblastoma
thyroid cancer associtated with RET oncogene
brain tumor a/w von hipple - linadu syndrome
child with eczema - coarse facial features - cold abscesses
deficiency of mannose phosphorylation

23. Inhibitory in the SC
chromosome 4
glycine
cough - conjunctivitis - coryza - fever
follicular

24. Primary hyperaldosteronism (HTN - hypokalemia - metabolic alkalosis)

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25. Superchiasmic nucleus
solitarius nucleus
master clock for circadian rhythms
nucleoside reverse transcriptase inhibitors
order of nerve blockade

26. Small diameter > large diameter; myelinated > unmyelinated
best effect on HDL
brain tumor with fried egg appearance
order of nerve blockade
smoking emphysema

27. Makes ADH
supraoptic nucleus of hypothalamus
myelinates on PNS
ovarian tumor with psammoma bodies
abruptio placentae

28. Chronic gout. inhibits reabsorbtion of uric acid in PCT
cancer arising from parafollicular C cells
abruptio placentae
catalase negative
probenecid

29. Hurlers
epithelial
What anti - hypertensive drug has the side effect of first dose orthostatic hypotension
corneal clouding & MR
Yolk sac tumor produces...

30. Lymphoma

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31. Fibroadenoma
chief cells
most common breast tumor in women under 25
anti - platelet antibodies
treatment of malignant hyperthermia

32. Kawasaki (treat with high dose aspirin)
locus ceruleus
strawberry tongue
found in hairless skin
What hormones share a common alpha subunit

33. Astrocytoma & glioblastoma multiforme
solitarius nucleus
eczema/recurrent infections/thrombocytopenia
GFAP positive
dose response curve change with competitive antagonist

34. A few levels above the level of entry
dermatin sulfate accumulation
Where does the spinothalamic decussate?
hemangioblastomas of retina/cerebellum/medulla
cancer arising from parafollicular C cells

35. Leydig cell tumor
Where does the lateral corticospinal decussate?
kluver bucy
testicular tumor that can present with gynecomastia
papillary thyroid cancer

36. Criglar Najar
raphe nucleus
TZD (glitazones) MofA
absent UTPGT
what meds treat malaria

37. H. Influenza
currant jelly stool
pt has extended expiratory phase
H. flu
gram + bacteria that requires NAD and hemin for growth

38. Yolk sac
most common testicular tumor in infants and children up to 3 years of age
cells destroyed in Guillain Barre
leydig cell tumor
microglia

39. TNF receptor
D cells
crinkled paper cytoplasm
SE: facial flushing
etanercept

40. Thryroxine replacement
most common testicular tumor in infants and children up to 3 years of age
catalase negative
MofA Levothyroxine
what nerve innervates the muscles of mastication?

41. Naloxone/naltrexone
enzyme used to conjugate bilirubin
most common arrthymia
lysosomal storage disease - demyelinating disease
opioids antidote

42. Incomplete fusion of processus vaginalis
hydrocele
most common arrthymia
21 hydroxylase deficiency
abruptio placentae

43. D cells of pancreas and gut
drug that blocks purine synthesis and is metabolized by xanthine oxidase
UMN signs
what cells secrete somatostatin
brain tumor with foamy cells and high vascularity

44. Motor innervation of pharynx - larynx and upper esophagus
LMN signs
medial geniculate nucleus
probenecid
ambiguous nucleus

45. Ach
hep B seropositivity in 30% of patients
drug induced lupus
brain tumor with psammona bodies
basal nucleus of Meynert

46. Decreased FEV/FVC ratio
hallmark sign of COPD
benzos antidote
drug induced lupus
strawberry tongue

47. Intussception
currant jelly stool
sclerosing adenosis
lysosomal storage disease a/w renal disease
most common breast cancer

48. Brenners tumor
midshaft break of humerus
ovarian tumor that resembles bladder epithelium
Galactocerebrosidase deficiency
dose response curve with noncompetitive antagonist

49. Panacinar
alpha 1 anti - trypsin
iduronidase sulfatase
form multinucleated giant cells in the CNS when infected with HIV
most common first line agent for septic shock

50. Sotalol - quinidine - cisapride
locus ceruleus
partial mole components
colchicine
SE: torsades de pointes

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USMLE Pathophys

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