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USMLE Pathophys

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Hemolysis - elevated LFTs - Low Platelets
HELLP syndrome
whats the V/Q at the apex of the lung
cause of LH surge
cancer arising from parafollicular C cells

2. Suspensory ligament of ovaries
eczema/recurrent infections/thrombocytopenia
VA/VL
contains ovarian vessels
Bisphosphonates MofA

3. Support - repair - potassium metabolism - remove excess NT - maintain BBB - marker is GFAP
myelinates on PNS
astrocytes
21 hydroxylase deficiency
lysosomal storage disease - demyelinating disease

4. Brenners tumor
ovarian tumor that resembles bladder epithelium
kawasaki
optically clear nuclei (orphan annie)
P450 inducers

5. Inner lining of ventricles - make CSF - originate from neuroectoderm
sulfonylureas MofA
Aschoff bodies
MPTP exposure causes depletion of what NT?
ependymal cells

6. Staph epidermidis - staph sapro
macrolides use (PUS)
oligodendrioglia
catalase positive coagulase negative
diphtheria treatment

7. ADPKD
Aschoff bodies
mitral valve prolapse - liver diseae - berry aneurysm
GABA - glutamine
pacinian

8. Actinomyces
what nerve innervates the muscles of mastication?
eczema/recurrent infections/thrombocytopenia
branching rods on oral infection
thayer martin media

9. Dobutamine
VA/VL
thromboxane A2
order of nerve blockade
first line for cardiogenic shock

10. Incomplete fusion of processus vaginalis
homer wright rosettes
leydig cell tumor
hydrocele
solitarius nucleus

11. Astrocytoma & glioblastoma multiforme
cause of LH surge
increased MCHC and hemolytic anemia
GFAP positive
hemangioblastomas of retina/cerebellum/medulla

12. Serous cystadenocarcinoma
von Hippel Lindau disease
form multinucleated giant cells in the CNS when infected with HIV
ovarian tumor with psammoma bodies
cancer associated with Hashimoto's thyroiditis

13. Gastrin
LTB4
G cells
silver stain of gram negative rods
SE: torsades de pointes

14. Hereditary spherocytosis
strawberry tongue
increased MCHC and hemolytic anemia
cause of malignant hyperthermia
oligodendrioglia

15. H. Influenza
hemosiderinurea and thrombosis
drug that blocks purine synthesis and is metabolized by xanthine oxidase
gram + bacteria that requires NAD and hemin for growth
palisading nuclei - locally invasive

16. Neurofibromatosis
branching rods on oral infection
lisch nodules
MofA Levothyroxine
sulfonylureas MofA

17. BCG PQRS
x- linked recessive lysosomal storage diseases
cause of LH surge
P450 inducers
antibiotic with SE of eosinophilia

18. Lactic acidosis
cause of low pH vaginal discharge
basal nucleus of Meynert
What are the hormone changes seen in menopause
metformin side effect

19. Sends autonomic fibers to heart
cause of increased myometrial excitability
master clock for circadian rhythms
dorsal motor nucleus
alpha L iduronidase

20. Homocystienuria - Marfans
5 alpha reductase deficiency
complete mole components
subluxation of lens
bocks PRPP synthetase to block purine synthesis

21. Papillary CA of thyroid - meningioma - mesothelioma - serous cystadenocarcinoma of ovary
lisch nodules
most common breast mass in postmenopausal women
deficiency of mannose phosphorylation
psammoma bodies

22. Dimercaprol
protease inhibitors MofA
Abciximab
lead antidote
tumor composed of cytotrophoblasts and syncytiotrophoblasts

23. Measles
tram - track on microscope
cough - conjunctivitis - coryza - fever
smoking emphysema
child with partial albinism - peripherial neuropathy - recurrent infections

24. Norepinephrine
17 alpha hydroxylase deficiency
3 tumors of MEN 2b
found in hairless skin
locus ceruleus

25. Dubin Johnson
grossly black liver
found in hairless skin
sarcoma botyroides
what inhibits prolactin secretion

26. Pacinian
resembles an onion in cross section
epithelial
cells destroyed in MS
sulfonylureas MofA

27. Decreased FEV/FVC ratio
ovarian tumor with elevate hCG
anti - epithelial antibodies
hallmark sign of COPD
smoking emphysema

28. Medullary thyroid - pheochromocytoma - oral/intestinal ganglionueromatosis
polyhydramnios
dorsal motor nucleus
TZD (glitazones) MofA
3 tumors of MEN 2b

29. Rheumatic fever
H. flu
basal nucleus of Meynert
Galactocerebrosidase deficiency
Aschoff bodies

30. Glutamate
precursor to GABA
most common breast mass in pre - menopausal women
colchicine
vasculitis a/w Hep B

31. Placenta attached to myometrium
optically clear nuclei (orphan annie)
treatment for SIADH
plenta accreta
follicular

32. Increases platelet aggregation and vasoconstriction
most common breast cancer
thromboxane A2
ovarian tumor with psammoma bodies
Conn's syndrome

33. Estrogen (causes precocious puberty)
PTU
granulosa cell tumor secretes what?
preeclampsia
supraoptic nucleus of hypothalamus

34. Sulfonamides - hydralazine - isonazid - procainamide - phenytoin
hemosiderinurea + thrombosis
drug induced lupus
treatment for SIADH
cause of LH surge

35. Second most common type of thyroid cancer
defective tyrosine kinase
dorsal motor nucleus
enzyme used to conjugate bilirubin
follicular

36. Visceral sensory
MPTP exposure causes depletion of what NT?
solitarius nucleus
whats the V/Q at the base of the lung
drug induced lupus

37. Fabry's & Hunters
solitarius nucleus
x- linked recessive lysosomal storage diseases
erythema nodosum
basal nucleus of Meynert

38. Niacin
first line for absence seizures
Yolk sac tumor produces...
SE: facial flushing
protease inhibitors MofA

39. Medullary
cancer arising from parafollicular C cells
meissners
ovarian tumor that resembles bladder epithelium
brenner tumor

40. Inhibits viral assembly
protease inhibitors MofA
astrocytes
treatment for SIADH
iduronidase sulfatase

41. Endometrial glands inside myometrium
contains ovarian vessels
adenomyosis
grossly black liver
3 tumors of MEN 2b

42. Visual (Lateral for Light)
Lateral geniculate nucleus
FGFR3 mutation
most common breast cancer
cells destroyed in MS

43. Vaginal carcinoma: spindle shaped tumor cells that are desmin positive
opioids antidote
sarcoma botyroides
pt has extended expiratory phase
G cells

44. Fibrates
blood supply for thalamus
best effect of triglycerides/VLDL
most common testicular tumor in infants and children up to 3 years of age
UMN signs

45. Schwann cells
myelinates on PNS
cause of LH surge
LMN signs
granulosa cell tumor secretes what?

46. Medulloblastoma
homer wright rosettes
LT C4 D4 E4
protease inhibitors MofA
cells destroyed in Guillain Barre

47. NE
catalase positive coagulase negative
dose response curve change with competitive antagonist
locus ceruleus
HELLP syndrome

48. Sotalol - quinidine - cisapride
21 hydroxylase deficiency
SE: torsades de pointes
SICK PEG
corneal clouding & MR

49. Inflammatory lesions of subq fat - usually on anterior shins. a/w infections
erythema nodosum
opioid withdrawal
cells destroyed in MS
most common first line agent for septic shock

50. Gonorrhea
thayer martin media
fusion inhibitors
subluxation of lens
first line for absence seizures