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Test your basic knowledge |
USMLE Pathophys
Start Test
Study First
Subjects
:
health-sciences
,
usmle
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Lactic acidosis
branching rods on oral infection
metformin side effect
subluxation of lens
UMN signs
2. Antibody binds to gp2b/3a - preventing aggregation
catalase positive coagulase negative
Abciximab
parietal cells
resembles an onion in cross section
3. Motor innervation of pharynx - larynx and upper esophagus
BCG PQRS
pacinian
x- linked recessive lysosomal storage diseases
ambiguous nucleus
4. Actinomyces
branching rods on oral infection
H. flu
thyroid cancer associtated with RET oncogene
homer wright rosettes
5. Ependymoma
brain tumor with perivascular pseudorosettes
brenner tumor
basal nucleus of Meynert
Where does the dorsal column decussate?
6. A few levels above the level of entry
Where does the spinothalamic decussate?
bocks PRPP synthetase to block purine synthesis
copper - arsenic - gold antidote
SE: facial flushing
7. Sulfonamides - Isonizid - Cimetidine - Ketoconazole - Erythromyicn - grapefruit juice - protease inhibitors
MPTP exposure causes depletion of what NT?
SICK PEG
defective tyrosine kinase
drug induced lupus
8. Trichomonas - Giardia
most common protozoal infection in US
heparin antidote
benzos antidote
t - PA - streptokinase antidote
9. Hypoglycemia
oligohydramnios
sulfonylureas side effect
most common bacteria in GI tract
neutrophils fail to respond to chemotaxic stimuli
10. BCG PQRS
P450 inducers
cause of increased myometrial excitability
what checkpoint is p53 involved with?
palisading nuclei - locally invasive
11. Inhibitory in the brain - stimulatory in the brain
GABA - glutamine
abruptio placentae
keratin filled cysts
SE: facial flushing
12. SCID
child with eczema - coarse facial features - cold abscesses
defective tyrosine kinase
form multinucleated giant cells in the CNS when infected with HIV
most common protozoal infection in US
13. Secretin
3 tumors of MEN 2a
first line for cardiogenic shock
S cells
D cells
14. Glucuronyl transferase
meissners
midshaft break of humerus
enzyme used to conjugate bilirubin
basal nucleus of Meynert
15. I- cell disease
pt has extended expiratory phase
deficiency of mannose phosphorylation
shown to slow progression of diabetic neuropathy
SICK PEG
16. Chediak - Higashi
cells destroyed in MS
catalase negative
first line for cardiogenic shock
child with partial albinism - peripherial neuropathy - recurrent infections
17. Fabry's & Hunters
macrolides use (PUS)
antibody against philadelphia chromosome
x- linked recessive lysosomal storage diseases
pt has extended expiratory phase
18. Yolk sac tumor
abruptio placentae
Schiller Duval bodies
meissners
antibody against philadelphia chromosome
19. Fibrates
glycine
first line for absence seizures
What causes coronary vasospasm as a SE?
best effect of triglycerides/VLDL
20. NF 1
SICK PEG
follicular
ovarian tumor with psammoma bodies
pigmented iris hamartomas - neural tumors
21. Basilar
What artery causes locked in syndrome
barbituates withdrawal
polyhydramnios
PGI2 (prostacyclin))
22. Anxiety - insomnia - sweating - dilated pupils - piloerection - rhinorrhea
opioid withdrawal
5 alpha reductase deficiency
most common breast tumor in women under 25
floppy mitral valve dissecting aortic aneurysm - berry aneurysm
23. 3
pseudopalisading necrosis
whats the V/Q at the apex of the lung
increased MCHC and hemolytic anemia
most common breast cancer
24. Dantrolene (prevents release of calcium from SR of muscle)
treatment of malignant hyperthermia
fusion inhibitors
may lead to multiple personalities
locus ceruleus
25. Tay SaX
cause of high pH vaginal discharge
heXosaminidase
Lateral geniculate nucleus
supraoptic nucleus of hypothalamus
26. Decreased potency - increased Km
dose response curve change with competitive antagonist
hemosiderinurea and thrombosis
sulfonylureas MofA
papillary thyroid cancer
27. Anti - TNF antibody - use for RA but watch out for latent TB!
shown to slow progression of diabetic neuropathy
infliximab
drug that blocks purine synthesis and is metabolized by xanthine oxidase
neutrophils fail to respond to chemotaxic stimuli
28. Posterior communicating - posterior cerebral - anterior choroidal arteries
blood supply for thalamus
treatment for SIADH
vasculitis of infants and children - involving coronary arteries
heXosaminidase
29. TNF receptor
etanercept
sphingomyelinase deficiency
strawberry tongue
what checkpoint is p53 involved with?
30. DiGeorge
midshaft break of humerus
failure of endodermal development
low dose ASA effects - intermediate dose - high dose
brain tumor a/w von hipple - linadu syndrome
31. ITP
blood supply for thalamus
HELLP syndrome
anti - platelet antibodies
treatment of malignant hyperthermia
32. Barbituates - carbamazapine - griseofulvin - phenytoin - quinidine - rifampin - St. John's wort
child with eczema - coarse facial features - cold abscesses
BCG PQRS
raphe nucleus
most common breast tumor in women under 25
33. 6- mecaptopurine (metabolized by xanthine oxidase)
BCG PQRS
beta glucocerebrosidase
hallmark sign of COPD
bocks PRPP synthetase to block purine synthesis
34. Deficiency of aldosterone and cortisol
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35. Gilberts
alpha L iduronidase
macrolides use (PUS)
mildly decreased UDPGT
Where does the spinothalamic decussate?
36. Pneumonia - URIs - STDS
macrolides use (PUS)
SE: torsades de pointes
contains ovarian vessels
cause of high pH vaginal discharge
37. Inflammatory lesions of subq fat - usually on anterior shins. a/w infections
hemangioblastomas of retina/cerebellum/medulla
ambiguous nucleus
psammoma bodies
erythema nodosum
38. Premature detachment of placenta - painful bleeding in 3rd trimester
etanercept
parietal cells
probenecid
abruptio placentae
39. Closes K+ channel on B cells causing depolarization and thus calcium influx which causes insulin release
chromosome 4
paraventricular nucleus of hypothalamus
BCG PQRS
sulfonylureas MofA
40. Chronic gout. inhibits reabsorbtion of uric acid in PCT
hydrocele
probenecid
thayer martin media
defective tyrosine kinase
41. 2 sperm + empty egg (no fetal parts)
whats the V/Q at the apex of the lung
complete mole components
SE: facial flushing
opioids antidote
42. Function as bronchoconstrictors - vasoconstrictors - sm mm contraction and increased vascular permability
LT C4 D4 E4
most common testicular tumor in infants and children up to 3 years of age
most common primary cardiac tumor in kiddos
form multinucleated giant cells in the CNS when infected with HIV
43. Primary biliary cirrhosis
LMN signs
lysosomal storage disease - demyelinating disease
GM2 ganglioside accumulation
anti - mitochondrial antibodies
44. Makes oxytocin
paraventricular nucleus of hypothalamus
GABA - glutamine
Yolk sac tumor produces...
epithelial
45. Von Hippel Lindau
D cells
hemangioblastomas of retina/cerebellum/medulla
defective tyrosine kinase
sphingomyelinase deficiency
46. Medulla
brain tumor with psammona bodies
Where does the dorsal column decussate?
FGFR3 mutation
whats the V/Q at the base of the lung
47. Endometrial glands inside myometrium
treatment of malignant hyperthermia
adenomyosis
thymidylate synthase
GFAP positive
48. Papillary CA of thyroid
which nerve lifts the eyelid?
iduronidase sulfatase
lewy body composition
optically clear nuclei (orphan annie)
49. Inner lining of ventricles - make CSF - originate from neuroectoderm
spike and dome on microscope
ependymal cells
absent UTPGT
kluver bucy
50. Prazosin
catalase negative
chromosome 4
nucleoside reverse transcriptase inhibitors
What anti - hypertensive drug has the side effect of first dose orthostatic hypotension