Test your basic knowledge |

USMLE Pathophys

Instructions:

Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can study here.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Cavernous hemangiomas in skin - mucosa & organs; autosomal dominant - a/w renal CA - hemangioblastoma in retina - brainstem & cerebellum
thayer martin media
HELLP syndrome
absent UTPGT
von Hippel Lindau disease

2. ADPKD
thymidylate synthase
SE: elevated LFTS - myositis
tram - track on microscope
mitral valve prolapse - liver diseae - berry aneurysm

3. Invasive ductal CA
nucleoside reverse transcriptase inhibitors
cause of malignant hyperthermia
most common breast mass in postmenopausal women
branching rods on oral infection

4. Small diameter > large diameter; myelinated > unmyelinated
keratin filled cysts
catalase negative
order of nerve blockade
anti - platelet antibodies

5. Choriocarcinoma
sturge weber syndrome
most common gyno malignancy
tumor composed of cytotrophoblasts and syncytiotrophoblasts
MofA Levothyroxine

6. Intrinsic factor
lysosomal storage disease a/w renal disease
brain tumor with fried egg appearance
chief cells
parietal cells

7. Medulla
Where does the lateral corticospinal decussate?
lead antidote
preeclampsia
myelinates on PNS

8. Auditory (Medial for Music)
what inhibits prolactin secretion
most common testicular tumor
medial geniculate nucleus
meissners

9. Posterior communicating - posterior cerebral - anterior choroidal arteries
blood supply for thalamus
master clock for circadian rhythms
Bisphosphonates MofA
I cells

10. Estrogen
sphingomyelinase deficiency
cause of increased myometrial excitability
protease inhibitors MofA
What artery causes locked in syndrome

11. 6- mecaptopurine (metabolized by xanthine oxidase)
diphtheria treatment
lysosomal storage disease a/w renal disease
bocks PRPP synthetase to block purine synthesis
P450 Inhibitors

12. Support - repair - potassium metabolism - remove excess NT - maintain BBB - marker is GFAP
master clock for circadian rhythms
astrocytes
order of nerve blockade
brenner tumor

13. Fibrates/statins
17 alpha hydroxylase deficiency
P450 Inhibitors
most common breast cancer
SE: elevated LFTS - myositis

14. Benign - contains Reinke crystals - usually androgen producing
drug that blocks purine synthesis and is metabolized by xanthine oxidase
heXosaminidase
leydig cell tumor
treatment of malignant hyperthermia

15. Antibody binds to gp2b/3a - preventing aggregation
ovarian tumor with psammoma bodies
hep B seropositivity in 30% of patients
Abciximab
keratin filled cysts

16. Anti - TNF antibody - use for RA but watch out for latent TB!
BCG PQRS
astrocytes
infliximab
What causes coronary vasospasm as a SE?

17. Gonorrhea
benzos antidote
thayer martin media
brain tumor with foamy cells and high vascularity
parietal cells

18. Ethosuximide
increased MCHC and hemolytic anemia
lead antidote
hydrocele
first line for absence seizures

19. Prevents incorporation into host DNA
PTU
nucleoside reverse transcriptase inhibitors
glycine
PGI2 (prostacyclin))

20. Neurofibromatosis
lisch nodules
Schiller Duval bodies
diphtheria treatment
gram + bacteria that requires NAD and hemin for growth

21. Trichomonas - Giardia
best effect on HDL
dorsal motor nucleus
most common protozoal infection in US
brain tumor with perivascular pseudorosettes

22. Polyarteritis nodosa
lewy body composition
midshaft break of humerus
which nerve lifts the eyelid?
vasculitis a/w Hep B

23. HTN - proteinuria - edema
found in hairless skin
Schiller Duval bodies
child with partial albinism - peripherial neuropathy - recurrent infections
preeclampsia

24. Metachromatic leukodystrophy
lysosomal storage disease - demyelinating disease
treatment of malignant hyperthermia
treatment for SIADH
barbituates withdrawal

25. Visceral sensory
thayer martin media
solitarius nucleus
D cells
thyroid cancer associtated with RET oncogene

26. Chronic gout. inhibits reabsorbtion of uric acid in PCT
Addison's
granulosa cell tumor secretes what?
probenecid
strawberry tongue

27. Fibrates
propylthiouracil side effects
best effect of triglycerides/VLDL
dermatin sulfate accumulation
ventral posterior nucleus - lateral part

28. Von Hippel Lindau
protease inhibitors MofA
hemangioblastomas of retina/cerebellum/medulla
benzos antidote
treatment for SIADH

29. Atrial fibrillation
copper - arsenic - gold antidote
most common arrthymia
Where does the lateral corticospinal decussate?
placenta previa

30. Dimercaprol
macrolides use (PUS)
solitarius nucleus
thromboxane A2
lead antidote

31. Invasive ductal
what checkpoint is p53 involved with?
keratin filled cysts
drug that blocks purine synthesis and is metabolized by xanthine oxidase
most common breast cancer

32. Decreased potency - increased Km
MPTP exposure causes depletion of what NT?
most common primary cardiac tumor in kiddos
Addison's
dose response curve change with competitive antagonist

33. 2 sperm + 1 egg (fetal parts present)
treatment for SIADH
dose response curve with noncompetitive antagonist
brain tumor a/w von hipple - linadu syndrome
partial mole components

34. Alpha synuclein
what nerve innervates the muscles of mastication?
catalase positive coagulase negative
most common breast mass in postmenopausal women
lewy body composition

35. Ret
metformin side effect
GFAP positive
blood supply for thalamus
What oncogene is a/w MEN 2a/b

36. Gauchers
medial geniculate nucleus
Where does the dorsal column decussate?
beta glucocerebrosidase
bocks PRPP synthetase to block purine synthesis

37. Flumazenil
hemangioblastomas of retina/cerebellum/medulla
testicular tumor that can present with gynecomastia
pt has extended expiratory phase
benzos antidote

38. Seborric keratosis
microglia
anti - platelet antibodies
keratin filled cysts
tumor with call - exner bodies

39. Hypoglycemia
LMN signs
sulfonylureas side effect
catalase negative
follicular

40. Secretin
S cells
lewy body composition
heXosaminidase
sclerosing adenosis

41. Amygdala
locus ceruleus
tram - track on microscope
best effect of triglycerides/VLDL
kluver bucy

42. Macrophages of the CNS
17 alpha hydroxylase deficiency
pt has extended expiratory phase
form multinucleated giant cells in the CNS when infected with HIV
microglia

43. Trigeminal
Abciximab
what nerve innervates the muscles of mastication?
Where does the dorsal column decussate?
adenomyosis

44. Hurlers - Hunters
thayer martin media
dermatin sulfate accumulation
absent UTPGT
most common breast tumor in women under 25

45. Decreases platelet aggregation - anti - pyretic and analgesic - high dose is anti - inflammatory
best effect on HDL
low dose ASA effects - intermediate dose - high dose
colchicine
cause of increased myometrial excitability

46. Regenerates glutathione
mitral valve prolapse - liver diseae - berry aneurysm
Bisphosphonates MofA
SE: elevated LFTS - myositis
MofA of N- aceylcysteine

47. Bilateral renal agenesis or posterior urethral valves in males
testicular tumor that can present with gynecomastia
precursor to GABA
oligohydramnios
cells destroyed in MS

48. Sends autonomic fibers to heart
sturge weber syndrome
keratin filled cysts
defective tyrosine kinase
dorsal motor nucleus

49. Second most common type of thyroid cancer
most common testicular tumor in infants and children up to 3 years of age
whats the V/Q at the apex of the lung
metformin side effect
follicular

50. Wiscott - Aldrich
most common breast mass in pre - menopausal women
cause of malignant hyperthermia
eczema/recurrent infections/thrombocytopenia
what meds treat malaria