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USMLE Pathophys

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Oligodendroglia
VA/VL
cause of high pH vaginal discharge
floppy mitral valve dissecting aortic aneurysm - berry aneurysm
looks like fried eggs under histologic staining

2. Oligodendoglia
Lateral geniculate nucleus
Abciximab
most common breast tumor in women under 25
myelinates multiple CNS axons

3. Decreases conversion
best effect of triglycerides/VLDL
cells destroyed in MS
PTU
What thyroid pathology has an extremely tender thyroid gland

4. Ependymoma
alpha 1 anti - trypsin
probenecid
barbituates withdrawal
brain tumor with perivascular pseudorosettes

5. Criglar Najar
hydrocele
dorsal motor nucleus
absent UTPGT
FGFR3 mutation

6. Facial sensation (Make up on your face)
ventral posterior nucleus - medial part
leydig cell tumor
What anti - hypertensive drug has the side effect of first dose orthostatic hypotension
precursor to GABA

7. Damaged in Guillian Barre
schwann cells
most common lysosomal storage disease
HELLP syndrome
myelinates multiple CNS axons

8. Kawasaki (treat with high dose aspirin)
anti - platelet antibodies
ventral posterior nucleus - lateral part
lewy body composition
strawberry tongue

9. Lactic acidosis
kawasaki
21 hydroxylase deficiency
corneal clouding & MR
metformin side effect

10. Closes K+ channel on B cells causing depolarization and thus calcium influx which causes insulin release
most common breast mass in postmenopausal women
sulfonylureas MofA
adenomyosis
lead antidote

11. Hurlers - Hunters
rate limiting step in carb digestion
Schiller Duval bodies
dermatin sulfate accumulation
barbituates withdrawal

12. Invasive ductal CA
sturge weber syndrome
3 tumors of MEN 1
most common breast mass in postmenopausal women
midshaft break of humerus

13. Incomplete fusion of processus vaginalis
hydrocele
lysosomal storage disease a/w renal disease
ambiguous nucleus
smoking emphysema

14. 3
abruptio placentae
tram - track on microscope
whats the V/Q at the apex of the lung
What oncogene is a/w MEN 2a/b

15. Aplastic anemia - rash - agranulocytosis
sturge weber syndrome
most common bacteria in GI tract
infliximab
propylthiouracil side effects

16. Seborric keratosis
keratin filled cysts
looks like fried eggs under histologic staining
5 alpha reductase deficiency
best effect on HDL

17. 5- fluorouracil
parietal cells
child with eczema - coarse facial features - cold abscesses
thymidylate synthase
dermatin sulfate accumulation

18. Hemolysis - elevated LFTs - Low Platelets
HELLP syndrome
cancer associated with Hashimoto's thyroiditis
honey crusted lesions common around nose/lips
SE: facial flushing

19. Vibration - pressure
glycine
floppy mitral valve dissecting aortic aneurysm - berry aneurysm
pacinian
MofA of N- aceylcysteine

20. Aminocaproic acid
lysosomal storage disease a/w renal disease
t - PA - streptokinase antidote
dermatin sulfate accumulation
tumor with call - exner bodies

21. Metachromatic leukodystrophy
myelinates on PNS
lysosomal storage disease - demyelinating disease
astrocytes
hydatidiform mole with crazy high hCG

22. Meissner
treatment of malignant hyperthermia
found in hairless skin
myelinates on PNS
silver stain of gram negative rods

23. Rhabdomyoma
sulfonylureas
SE: elevated LFTS - myositis
most common primary cardiac tumor in kiddos
GABA - glutamine

24. Medullary thyroid - pheochromocytoma - parathryoid
3 tumors of MEN 2a
mitral valve prolapse - liver diseae - berry aneurysm
fusion inhibitors
optically clear nuclei (orphan annie)

25. Prevents incorporation into host DNA
vasculitis of infants and children - involving coronary arteries
subluxation of lens
nucleoside reverse transcriptase inhibitors
Addison's

26. Amygdala
kluver bucy
Where does the spinothalamic decussate?
papillary thyroid cancer
most common protozoal infection in US

27. Estrogen
Lateral geniculate nucleus
whats the V/Q at the apex of the lung
cause of LH surge
brain tumor with perivascular pseudorosettes

28. Deficiency of aldosterone and cortisol

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29. S-100
melanoma tumor marker
lysosomal storage disease a/w renal disease
cause of LH surge
keratin filled cysts

30. Huntingtons chorea
chromosome 4
cause of low pH vaginal discharge
testicular tumor that can present with gynecomastia
SICK PEG

31. Hereditary spherocytosis
most common testicular tumor
increased MCHC and hemolytic anemia
hallmark sign of COPD
silver stain of gram negative rods

32. Tay Sachs
catalase positive coagulase negative
GM2 ganglioside accumulation
tumor composed of cytotrophoblasts and syncytiotrophoblasts
basal nucleus of Meynert

33. Glucuronyl transferase
enzyme used to conjugate bilirubin
intranuclear inclusions seen in herpes simplex encephalitis
branching rods on oral infection
tumor with call - exner bodies

34. Hurlers
hemangioblastomas of retina/cerebellum/medulla
smoking emphysema
brain tumor with fried egg appearance
corneal clouding & MR

35. Increases platelet aggregation and vasoconstriction
opioid withdrawal
vasculitis of infants and children - involving coronary arteries
thromboxane A2
H. flu

36. Auditory (Medial for Music)
hydrocele
medial geniculate nucleus
copper - arsenic - gold antidote
antibody against philadelphia chromosome

37. Anxiety - insomnia - sweating - dilated pupils - piloerection - rhinorrhea
most common primary cardiac tumor in kiddos
opioid withdrawal
11 beta hydroxylase deficiency
follicular

38. Granulosa cell tumor
What causes coronary vasospasm as a SE?
anti - mitochondrial antibodies
tumor with call - exner bodies
anti - platelet antibodies

39. Cell type involved in most ovarian tumors
whats the V/Q at the base of the lung
21 hydroxylase deficiency
ambiguous nucleus
epithelial

40. Inhibits platelet aggregation - promotes vasodilation and decreases uterine tone
rate limiting step in carb digestion
von Hippel Lindau disease
treatment of malignant hyperthermia
PGI2 (prostacyclin))

41. NE
hallmark sign of COPD
midshaft break of humerus
most common first line agent for septic shock
What thyroid pathology has an extremely tender thyroid gland

42. ITP
optically clear nuclei (orphan annie)
SE: torsades de pointes
anti - platelet antibodies
VA/VL

43. Clopidogrel - ticoplidine
SE: elevated LFTS - myositis
failure of endodermal development
locus ceruleus
blocks ADP receptors to inhibit platelet aggregation

44. Gastrin
MPTP exposure causes depletion of what NT?
vasculitis a/w Hep B
most common primary cardiac tumor in kiddos
G cells

45. Schwann cells
dose response curve with noncompetitive antagonist
PGI2 (prostacyclin))
myelinates on PNS
What hormones share a common alpha subunit

46. Most common type of thyroid cancer
What anti - hypertensive drug has the side effect of first dose orthostatic hypotension
thymidylate synthase
heXosaminidase
papillary thyroid cancer

47. Bruton's agammaglobulinemia
looks like fried eggs under histologic staining
most common testicular tumor in infants and children up to 3 years of age
treatment for SIADH
defective tyrosine kinase

48. Ret
chromosome 4
most common testicular tumor in infants and children up to 3 years of age
What oncogene is a/w MEN 2a/b
may lead to multiple personalities

49. Inhibits osteoclastic activity
Abciximab
epithelial
Bisphosphonates MofA
x- linked recessive lysosomal storage diseases

50. Ach
abruptio placentae
supraoptic nucleus of hypothalamus
basal nucleus of Meynert
schwann cells