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USMLE Pathophys

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Oligosaccaride hydrolase
rate limiting step in carb digestion
what meds treat malaria
failure of endodermal development
tumor composed of cytotrophoblasts and syncytiotrophoblasts

2. Astrocytoma & glioblastoma multiforme
plenta accreta
astrocytes
GFAP positive
cause of low pH vaginal discharge

3. Hemolysis - elevated LFTs - Low Platelets
H. flu
TZD (glitazones) MofA
HELLP syndrome
brain tumor a/w von hipple - linadu syndrome

4. Basilar
What artery causes locked in syndrome
17 alpha hydroxylase deficiency
sclerosing adenosis
partial mole components

5. Invasive ductal
optically clear nuclei (orphan annie)
most common breast tumor in women under 25
most common breast cancer
catalase negative

6. Dissociative
treatment of malignant hyperthermia
intranuclear inclusions seen in herpes simplex encephalitis
may lead to multiple personalities
what cells secrete somatostatin

7. Makes ADH
supraoptic nucleus of hypothalamus
master clock for circadian rhythms
Lateral geniculate nucleus
defective tyrosine kinase

8. Placenta attached to myometrium
most common breast mass in postmenopausal women
cause of low pH vaginal discharge
order of nerve blockade
plenta accreta

9. Papillary CA of thyroid
papillary thyroid cancer
drug that blocks purine synthesis and is metabolized by xanthine oxidase
optically clear nuclei (orphan annie)
basal nucleus of Meynert

10. Polyarteritis nodosa
MofA of N- aceylcysteine
antibiotic with SE of eosinophilia
vasculitis a/w Hep B
anti - epithelial antibodies

11. Marfans
best effect on HDL
rate limiting step in carb digestion
intranuclear inclusions seen in herpes simplex encephalitis
floppy mitral valve dissecting aortic aneurysm - berry aneurysm

12. Tay SaX
heXosaminidase
cough - conjunctivitis - coryza - fever
pigmented iris hamartomas - neural tumors
sulfonylureas MofA

13. Cant convert testosterone to DHT - ambiguous genitalia until puberty then penis at 12
catalase positive coagulase negative
5 alpha reductase deficiency
tram - track on microscope
GM2 ganglioside accumulation

14. Alpha synuclein
cause of LH surge
What thyroid pathology has an extremely tender thyroid gland
hemosiderinurea and thrombosis
Lewy bodies composition

15. Panacinar
rate limiting step in carb digestion
alpha 1 anti - trypsin
SE: facial flushing
kawasaki

16. Motor innervation of pharynx - larynx and upper esophagus
alpha 1 anti - trypsin
deficiency of mannose phosphorylation
ambiguous nucleus
silver stain of gram negative rods

17. Trichomonas - Giardia
most common gyno malignancy
alpha L iduronidase
most common protozoal infection in US
sulfonylureas

18. Granulosa cell tumor
brain tumor with perivascular pseudorosettes
tumor with call - exner bodies
hippocampus
H. flu

19. Kawasaki
child with eczema - coarse facial features - cold abscesses
vasculitis of infants and children - involving coronary arteries
grossly black liver
found in hairless skin

20. Visual (Lateral for Light)
Lewy bodies composition
PTU
sumatriptan
Lateral geniculate nucleus

21. Negri bodies
ovarian tumor with elevate hCG
rabies
lisch nodules
thromboxane A2

22. 6- mecaptopurine (metabolized by xanthine oxidase)
cough - conjunctivitis - coryza - fever
bocks PRPP synthetase to block purine synthesis
first line for cardiogenic shock
most common breast mass in pre - menopausal women

23. Alpha feto protein
antibiotic with SE of eosinophilia
diphtheria treatment
Yolk sac tumor produces...
HELLP syndrome

24. Actinomyces
branching rods on oral infection
sulfonylureas
bocks PRPP synthetase to block purine synthesis
most common testicular tumor

25. Antibody binds to gp2b/3a - preventing aggregation
SE: torsades de pointes
infliximab
MPTP exposure causes depletion of what NT?
Abciximab

26. Increased acini and intralobular fibrosis
most common first line agent for septic shock
S cells
sclerosing adenosis
branching rods on oral infection

27. Combo of inhaled anesthetics & succinylcholine
cause of malignant hyperthermia
most common gyno malignancy
treatment of malignant hyperthermia
oligodendrioglia

28. A/w esophageal/duodenal atresia and anencephaly
erythema nodosum
rate limiting step in carb digestion
polyhydramnios
precursor to GABA

29. Dimercaprol
lead antidote
benzos antidote
G cells
MofA Levothyroxine

30. Oculomotor
anti - mitochondrial antibodies
which nerve lifts the eyelid?
cough - conjunctivitis - coryza - fever
diphtheria treatment

31. Thryroxine replacement
MofA Levothyroxine
best effect of triglycerides/VLDL
absent UTPGT
I cells

32. Hemangioblastoma
brain tumor a/w von hipple - linadu syndrome
ventral posterior nucleus - medial part
smoking emphysema
21 hydroxylase deficiency

33. Protamine sulfate
Where does the dorsal column decussate?
heparin antidote
LMN signs
dermatin sulfate accumulation

34. Hereditary spherocytosis
polyhydramnios
increased MCHC and hemolytic anemia
most common testicular tumor
What are the hormone changes seen in menopause

35. Penicillamine
copper - arsenic - gold antidote
brain tumor with fried egg appearance
deficiency of mannose phosphorylation
what cells secrete somatostatin

36. Microglia
branching rods on oral infection
form multinucleated giant cells in the CNS when infected with HIV
macrolides use (PUS)
branching rods on oral infection

37. Huntingtons chorea
chromosome 4
enzyme used to conjugate bilirubin
propylthiouracil side effects
catalase negative

38. Primary hyperaldosteronism (HTN - hypokalemia - metabolic alkalosis)

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39. HTN - proteinuria - edema
preeclampsia
pigmented iris hamartomas - neural tumors
hemosiderinurea + thrombosis
subluxation of lens

40. Medulloblastoma
Yolk sac tumor produces...
cause of high pH vaginal discharge
homer wright rosettes
D cells

41. Glioblastoma multiforme
PGI2 (prostacyclin))
sclerosing adenosis
most common breast mass in pre - menopausal women
pseudopalisading necrosis

42. Hemangioblastoma
brain tumor with foamy cells and high vascularity
propylthiouracil side effects
meissners
TZD (glitazones) MofA

43. Seminoma
What causes coronary vasospasm as a SE?
most common testicular tumor
sclerosing adenosis
looks like fried eggs under histologic staining

44. HTN; masculinization
precursor to GABA
microglia
most common primary cardiac tumor in kiddos
11 beta hydroxylase deficiency

45. Superchiasmic nucleus
plenta accreta
psammoma bodies
master clock for circadian rhythms
failure of endodermal development

46. Auditory (Medial for Music)
basal nucleus of Meynert
medial geniculate nucleus
antibody against philadelphia chromosome
protease inhibitors MofA

47. Cowdry type A inclusions
astrocytes
intranuclear inclusions seen in herpes simplex encephalitis
LT C4 D4 E4
treatment of malignant hyperthermia

48. Hurlers - Hunters
barbituates withdrawal
most common lysosomal storage disease
what cells secrete somatostatin
dermatin sulfate accumulation

49. ITP
heparin antidote
anti - platelet antibodies
silver stain of gram negative rods
dermatin sulfate accumulation

50. Brenners tumor
heXosaminidase
intranuclear inclusions seen in herpes simplex encephalitis
inheritance pattern for all MENs
ovarian tumor that resembles bladder epithelium