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USMLE Pathophys

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Hairless skin - dynamic fine touch
meissners
sulfonylureas MofA
kluver bucy
crinkled paper cytoplasm

2. Staph epidermidis - staph sapro
cause of high pH vaginal discharge
whats the V/Q at the base of the lung
catalase positive coagulase negative
hep B seropositivity in 30% of patients

3. NF 1
bocks PRPP synthetase to block purine synthesis
most common gyno malignancy
pigmented iris hamartomas - neural tumors
thromboxane A2

4. Secretin
blocks ADP receptors to inhibit platelet aggregation
S cells
opioids antidote
silver stain of gram negative rods

5. Kawasaki
vasculitis of infants and children - involving coronary arteries
cause of low pH vaginal discharge
myelinates multiple CNS axons
most common testicular tumor in infants and children up to 3 years of age

6. TNF receptor
rabies
catalase positive coagulase negative
etanercept
strawberry tongue

7. Bilateral renal agenesis or posterior urethral valves in males
alpha 1 anti - trypsin
oligohydramnios
anti - mitochondrial antibodies
Conn's syndrome

8. Niacin
SE: facial flushing
enzyme used to conjugate bilirubin
child with eczema - coarse facial features - cold abscesses
basal nucleus of Meynert

9. Von Hippel Lindau
plenta accreta
eczema/recurrent infections/thrombocytopenia
hemangioblastomas of retina/cerebellum/medulla
currant jelly stool

10. Bromocriptine
3 tumors of MEN 2b
optically clear nuclei (orphan annie)
what inhibits prolactin secretion
looks like fried eggs under histologic staining

11. Alpha synuclein
Lewy bodies composition
form multinucleated giant cells in the CNS when infected with HIV
order of nerve blockade
etanercept

12. Inflammatory lesions of subq fat - usually on anterior shins. a/w infections
partial mole components
iduronidase sulfatase
erythema nodosum
glycine

13. H. Influenza
Lateral geniculate nucleus
hydrocele
gram + bacteria that requires NAD and hemin for growth
kawasaki

14. Rheumatic fever
5 alpha reductase deficiency
Aschoff bodies
preeclampsia
inheritance pattern for all MENs

15. Ethosuximide
first line for absence seizures
child with eczema - coarse facial features - cold abscesses
iduronidase sulfatase
currant jelly stool

16. ITP
what meds treat malaria
contains ovarian vessels
Conn's syndrome
anti - platelet antibodies

17. Prazosin
What anti - hypertensive drug has the side effect of first dose orthostatic hypotension
ependymal cells
brain tumor with foamy cells and high vascularity
hydrocele

18. Wiscott - Aldrich
honey crusted lesions common around nose/lips
subluxation of lens
eczema/recurrent infections/thrombocytopenia
thymidylate synthase

19. Incomplete fusion of processus vaginalis
basal nucleus of Meynert
iduronidase sulfatase
copper - arsenic - gold antidote
hydrocele

20. NE
diphtheria treatment
most common first line agent for septic shock
papillary thyroid cancer
cause of malignant hyperthermia

21. Closes K+ channel on B cells causing depolarization and thus calcium influx which causes insulin release
spike and dome on microscope
hippocampus
LT C4 D4 E4
sulfonylureas MofA

22. Suspensory ligament of ovaries
bocks PRPP synthetase to block purine synthesis
contains ovarian vessels
ambiguous nucleus
LTB4

23. Estrogen
branching rods on oral infection
cause of increased myometrial excitability
pacinian
thromboxane A2

24. Negri bodies
rabies
order of nerve blockade
most common breast mass in pre - menopausal women
MofA Levothyroxine

25. Astrocytoma & glioblastoma multiforme
GFAP positive
Where does the spinothalamic decussate?
dermatin sulfate accumulation
cause of malignant hyperthermia

26. Alpha feto protein
antibody against philadelphia chromosome
most common primary cardiac tumor in kiddos
5 alpha reductase deficiency
Yolk sac tumor produces...

27. DiGeorge
failure of endodermal development
ventral posterior nucleus - medial part
mitral valve prolapse - liver diseae - berry aneurysm
BCG PQRS

28. Fibrocystic
most common breast mass in pre - menopausal women
found in hairless skin
MPTP exposure causes depletion of what NT?
leydig cell tumor

29. Actinomyces
currant jelly stool
microglia
branching rods on oral infection
PTU

30. Membranoproliferative GN
hydatidiform mole with crazy high hCG
sulfonylureas
tram - track on microscope
iduronidase sulfatase

31. Trigeminal
what nerve innervates the muscles of mastication?
von Hippel Lindau disease
iduronidase sulfatase
ovarian tumor with psammoma bodies

32. Oculomotor
brain tumor with foamy cells and high vascularity
dorsal motor nucleus
inheritance pattern for all MENs
which nerve lifts the eyelid?

33. Cavernous hemangiomas in skin - mucosa & organs; autosomal dominant - a/w renal CA - hemangioblastoma in retina - brainstem & cerebellum
von Hippel Lindau disease
vasculitis of infants and children - involving coronary arteries
treatment of malignant hyperthermia
placenta previa

34. Meissner
What are the hormone changes seen in menopause
thyroid cancer associtated with RET oncogene
sulfonylureas side effect
found in hairless skin

35. Endometrial CA
Bisphosphonates MofA
treatment of malignant hyperthermia
SE: torsades de pointes
most common gyno malignancy

36. ACE inhibitors
subluxation of lens
GABA - glutamine
pt has extended expiratory phase
shown to slow progression of diabetic neuropathy

37. Prevents incorporation into host DNA
heXosaminidase
nucleoside reverse transcriptase inhibitors
Lewy bodies composition
absent UTPGT

38. Kawasaki (treat with high dose aspirin)
myelinates multiple CNS axons
strawberry tongue
propylthiouracil side effects
lead antidote

39. Inner lining of ventricles - make CSF - originate from neuroectoderm
shown to slow progression of diabetic neuropathy
optically clear nuclei (orphan annie)
ependymal cells
5 alpha reductase deficiency

40. Cowdry type A inclusions
intranuclear inclusions seen in herpes simplex encephalitis
dermatin sulfate accumulation
MofA Levothyroxine
shown to slow progression of diabetic neuropathy

41. CCK
thyroid cancer associtated with RET oncogene
I cells
blocks ADP receptors to inhibit platelet aggregation
3 tumors of MEN 1

42. Neutrophil chemotactic agent 'neutrophils arrive B4 others'
LTB4
What thyroid pathology has an extremely tender thyroid gland
diphtheria treatment
thromboxane A2

43. Macrolides
antibiotic with SE of eosinophilia
What thyroid pathology has an extremely tender thyroid gland
whats the V/Q at the base of the lung
cause of high pH vaginal discharge

44. Fibrates
best effect of triglycerides/VLDL
epithelial
subluxation of lens
child with eczema - coarse facial features - cold abscesses

45. Choriocarcinoma
tumor composed of cytotrophoblasts and syncytiotrophoblasts
What oncogene is a/w MEN 2a/b
thyroid cancer associtated with RET oncogene
Galactocerebrosidase deficiency

46. Dimercaprol
Conn's syndrome
lead antidote
sclerosing adenosis
ventral posterior nucleus - medial part

47. Dobutamine
alpha L iduronidase
myelinates multiple CNS axons
anti - platelet antibodies
first line for cardiogenic shock

48. Macconkey's agar
P450 Inhibitors
ovarian tumor with elevate hCG
Shigella
cause of increased myometrial excitability

49. G1/S & G2/M
what checkpoint is p53 involved with?
astrocytes
abruptio placentae
tumor composed of cytotrophoblasts and syncytiotrophoblasts

50. Decreased FEV/FVC ratio
hallmark sign of COPD
best effect on HDL
3 tumors of MEN 1
psammoma bodies