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USMLE Pathophys

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Pacinian
vasculitis a/w Hep B
follicular
nucleoside reverse transcriptase inhibitors
resembles an onion in cross section

2. PNH
Abciximab
hemosiderinurea and thrombosis
5 alpha reductase deficiency
most common breast mass in postmenopausal women

3. Fabry's & Hunters
MofA Levothyroxine
x- linked recessive lysosomal storage diseases
cells destroyed in MS
t - PA - streptokinase antidote

4. Memory
lewy body composition
mildly decreased UDPGT
myelinates on PNS
hippocampus

5. SCID
leydig cell tumor
child with eczema - coarse facial features - cold abscesses
dorsal motor nucleus
ambiguous nucleus

6. Hurlers - Hunters
brain tumor with foamy cells and high vascularity
most common lysosomal storage disease
dermatin sulfate accumulation
hydrocele

7. Second most common type of thyroid cancer
follicular
H. flu
first line for cardiogenic shock
What anti - hypertensive drug has the side effect of first dose orthostatic hypotension

8. Inflammatory lesions of subq fat - usually on anterior shins. a/w infections
erythema nodosum
most common bacteria in GI tract
dose response curve with noncompetitive antagonist
sulfonylureas side effect

9. Oligosaccaride hydrolase
What causes coronary vasospasm as a SE?
rate limiting step in carb digestion
keratin filled cysts
most common testicular tumor in infants and children up to 3 years of age

10. Atrial fibrillation
may lead to multiple personalities
child with eczema - coarse facial features - cold abscesses
epithelial
most common arrthymia

11. Prevents incorporation into host DNA
nucleoside reverse transcriptase inhibitors
macrolides use (PUS)
cause of LH surge
antibiotic with SE of eosinophilia

12. Estrogen (causes precocious puberty)
whats the V/Q at the apex of the lung
glycine
granulosa cell tumor secretes what?
G cells

13. Astrocytoma & glioblastoma multiforme
cause of LH surge
GFAP positive
brain tumor with perivascular pseudorosettes
looks like fried eggs under histologic staining

14. Babinski - weakness - increased reflexes & tone - spastic paralysis
FGFR3 mutation
found in hairless skin
ovarian tumor that resembles bladder epithelium
UMN signs

15. Anxiety - insomnia - sweating - dilated pupils - piloerection - rhinorrhea
shown to slow progression of diabetic neuropathy
medial geniculate nucleus
defective tyrosine kinase
opioid withdrawal

16. Intrinsic factor
kluver bucy
brain tumor with perivascular pseudorosettes
parietal cells
spike and dome on microscope

17. Cocain and sumatriptan
lysosomal storage disease - demyelinating disease
What causes coronary vasospasm as a SE?
chief cells
papillary thyroid cancer

18. Invasive ductal CA
Lewy bodies composition
most common breast mass in postmenopausal women
what checkpoint is p53 involved with?
infliximab

19. Hurlers
hallmark sign of COPD
What thyroid pathology has an extremely tender thyroid gland
form multinucleated giant cells in the CNS when infected with HIV
corneal clouding & MR

20. Bromocriptine
what inhibits prolactin secretion
placenta previa
diphtheria treatment
partial mole components

21. Gauchers
most common lysosomal storage disease
MofA Levothyroxine
rate limiting step in carb digestion
failure of endodermal development

22. Endometrial glands inside myometrium
adenomyosis
subluxation of lens
follicular
which nerve lifts the eyelid?

23. Combo of inhaled anesthetics & succinylcholine
Where does the dorsal column decussate?
myelinates multiple CNS axons
cause of malignant hyperthermia
increased MCHC and hemolytic anemia

24. Oligodendoglia
first line for absence seizures
parietal cells
myelinates multiple CNS axons
catalase positive coagulase negative

25. Bruton's agammaglobulinemia
PGI2 (prostacyclin))
cause of LH surge
ventral posterior nucleus - medial part
defective tyrosine kinase

26. Weakness - atrophy - fasiculations - decreased reflexes & tone
Addison's
LMN signs
SE: elevated LFTS - myositis
What causes coronary vasospasm as a SE?

27. Gauchers
GFAP positive
hydrocele
beta glucocerebrosidase
barbituates withdrawal

28. Macconkey's agar
Shigella
colchicine
anti - platelet antibodies
G cells

29. Body sensation
3 tumors of MEN 2b
hemosiderinurea + thrombosis
ventral posterior nucleus - lateral part
most common testicular tumor

30. G1/S & G2/M
psammoma bodies
Where does the spinothalamic decussate?
what checkpoint is p53 involved with?
opioids antidote

31. Ach
opioid withdrawal
locus ceruleus
11 beta hydroxylase deficiency
basal nucleus of Meynert

32. Tay SaX
cells destroyed in Guillain Barre
heXosaminidase
deficiency of mannose phosphorylation
meissners

33. Fibrates/statins
tumor with call - exner bodies
SE: elevated LFTS - myositis
increased MCHC and hemolytic anemia
sclerosing adenosis

34. Cant convert testosterone to DHT - ambiguous genitalia until puberty then penis at 12
17 alpha hydroxylase deficiency
5 alpha reductase deficiency
adenomyosis
rate limiting step in carb digestion

35. Primary hyperaldosteronism (HTN - hypokalemia - metabolic alkalosis)

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36. Krabbe's
hemosiderinurea and thrombosis
rate limiting step in carb digestion
locus ceruleus
Galactocerebrosidase deficiency

37. Motor innervation of pharynx - larynx and upper esophagus
copper - arsenic - gold antidote
ambiguous nucleus
cancer associated with Hashimoto's thyroiditis
GABA - glutamine

38. Bilateral renal agenesis or posterior urethral valves in males
propylthiouracil side effects
oligohydramnios
most common arrthymia
sphingomyelinase deficiency

39. Von Hippel Lindau
partial mole components
strawberry tongue
hemangioblastomas of retina/cerebellum/medulla
copper - arsenic - gold antidote

40. Staph epidermidis - staph sapro
hallmark sign of COPD
sulfonylureas side effect
adenomyosis
catalase positive coagulase negative

41. Damaged in Guillian Barre
Bisphosphonates MofA
sturge weber syndrome
schwann cells
catalase positive coagulase negative

42. Sends autonomic fibers to heart
Lewy bodies composition
dorsal motor nucleus
SE: torsades de pointes
lysosomal storage disease a/w renal disease

43. Cell type involved in most ovarian tumors
ventral posterior nucleus - medial part
anti - platelet antibodies
epithelial
Lateral geniculate nucleus

44. Bind viral gp41 subunit
TZD (glitazones) MofA
what nerve innervates the muscles of mastication?
Lewy bodies composition
fusion inhibitors

45. TSH - LH - FSH - hCG
PGI2 (prostacyclin))
branching rods on oral infection
What hormones share a common alpha subunit
most common protozoal infection in US

46. Fabrys
pseudopalisading necrosis
most common first line agent for septic shock
alpha galacosidase A
failure of endodermal development

47. Measles
cough - conjunctivitis - coryza - fever
astrocytes
cause of LH surge
kluver bucy

48. Masculinization - hypovolemic shock
most common testicular tumor in infants and children up to 3 years of age
21 hydroxylase deficiency
vasculitis of infants and children - involving coronary arteries
papillary thyroid cancer

49. Oligodendroglia
What are the hormone changes seen in menopause
looks like fried eggs under histologic staining
Where does the lateral corticospinal decussate?
rate limiting step in carb digestion

50. PNH
most common gyno malignancy
hemosiderinurea + thrombosis
brain tumor a/w von hipple - linadu syndrome
ovarian tumor that resembles bladder epithelium