Test your basic knowledge |

USMLE Pathophys

Instructions:

Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can study here.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Causes vasoconstriction (use for acute migraines)
palisading nuclei - locally invasive
best effect on HDL
sumatriptan
oligodendrioglia

2. Damaged in multiple sclerosis
spike and dome on microscope
oligodendrioglia
HELLP syndrome
astrocytes

3. Niacin
treatment of malignant hyperthermia
SE: facial flushing
complete mole components
what meds treat malaria

4. Radial nerve - deep brachial artery
absent UTPGT
infliximab
papillary thyroid cancer
midshaft break of humerus

5. Hemangioblastoma
brain tumor with foamy cells and high vascularity
hydrocele
5 alpha reductase deficiency
hep B seropositivity in 30% of patients

6. Negri bodies
P450 inducers
rabies
BCG PQRS
brain tumor with perivascular pseudorosettes

7. Chronic gout. inhibits reabsorbtion of uric acid in PCT
probenecid
cause of high pH vaginal discharge
shown to slow progression of diabetic neuropathy
myelinates multiple CNS axons

8. Job's or LAD
brain tumor with psammona bodies
most common testicular tumor
deficiency of mannose phosphorylation
neutrophils fail to respond to chemotaxic stimuli

9. Dobutamine
first line for cardiogenic shock
solitarius nucleus
brain tumor with foamy cells and high vascularity
preeclampsia

10. Visual (Lateral for Light)
Where does the lateral corticospinal decussate?
Lateral geniculate nucleus
sulfonylureas
hemosiderinurea + thrombosis

11. Cocain and sumatriptan
fusion inhibitors
What causes coronary vasospasm as a SE?
leydig cell tumor
preeclampsia

12. Cells of BBB
raphe nucleus
lisch nodules
astrocytes
colchicine

13. NE
sturge weber syndrome
MofA Levothyroxine
most common first line agent for septic shock
etanercept

14. Dantrolene (prevents release of calcium from SR of muscle)
testicular tumor that can present with gynecomastia
cause of LH surge
treatment of malignant hyperthermia
precursor to GABA

15. Hunters
iduronidase sulfatase
contains ovarian vessels
hippocampus
most common lysosomal storage disease

16. Decreased efficacy - decreased Vmax
iduronidase sulfatase
sarcoma botyroides
honey crusted lesions common around nose/lips
dose response curve with noncompetitive antagonist

17. Motor innervation of pharynx - larynx and upper esophagus
hemangioblastomas of retina/cerebellum/medulla
contains ovarian vessels
ambiguous nucleus
Lewy bodies composition

18. Measles
subluxation of lens
erythema nodosum
solitarius nucleus
cough - conjunctivitis - coryza - fever

19. Oligodendrogila
cells destroyed in MS
most common gyno malignancy
VA/VL
gram + bacteria that requires NAD and hemin for growth

20. Glutamate
precursor to GABA
grossly black liver
cause of LH surge
sulfonylureas

21. Suspensory ligament of ovaries
eczema/recurrent infections/thrombocytopenia
contains ovarian vessels
UMN signs
first line for cardiogenic shock

22. Choriocarcinoma
tumor composed of cytotrophoblasts and syncytiotrophoblasts
D cells
copper - arsenic - gold antidote
Bisphosphonates MofA

23. Gauchers
crinkled paper cytoplasm
precursor to GABA
drug induced lupus
hydrocele

24. Glioblastoma multiforme
pseudopalisading necrosis
beta glucocerebrosidase
x- linked recessive lysosomal storage diseases
Aschoff bodies

25. 6- mecaptopurine (metabolized by xanthine oxidase)
bocks PRPP synthetase to block purine synthesis
lewy body composition
t - PA - streptokinase antidote
best effect of triglycerides/VLDL

26. Lactic acidosis
pacinian
alpha L iduronidase
lewy body composition
metformin side effect

27. Bromocriptine
3 tumors of MEN 1
first line for cardiogenic shock
fusion inhibitors
what inhibits prolactin secretion

28. Von Hippel Lindau
alpha galacosidase A
hemangioblastomas of retina/cerebellum/medulla
bocks PRPP synthetase to block purine synthesis
Where does the lateral corticospinal decussate?

29. Clopidogrel - ticoplidine
blocks ADP receptors to inhibit platelet aggregation
Where does the dorsal column decussate?
defective tyrosine kinase
corneal clouding & MR

30. Krabbe's
3 tumors of MEN 1
rate limiting step in carb digestion
vasculitis of infants and children - involving coronary arteries
Galactocerebrosidase deficiency

31. Superchiasmic nucleus
fusion inhibitors
master clock for circadian rhythms
order of nerve blockade
most common primary cardiac tumor in kiddos

32. D cells of pancreas and gut
what cells secrete somatostatin
cause of malignant hyperthermia
spike and dome on microscope
found in hairless skin

33. Hypoglycemia
sulfonylureas side effect
Schiller Duval bodies
thromboxane A2
beta glucocerebrosidase

34. Second most common type of thyroid cancer
most common protozoal infection in US
ovarian tumor with psammoma bodies
resembles an onion in cross section
follicular

35. Normal or candida
cause of low pH vaginal discharge
drug that blocks purine synthesis and is metabolized by xanthine oxidase
macrolides use (PUS)
What hormones share a common alpha subunit

36. Oligodendrioma
What anti - hypertensive drug has the side effect of first dose orthostatic hypotension
brain tumor with fried egg appearance
deficiency of mannose phosphorylation
cause of high pH vaginal discharge

37. Vibration - pressure
infliximab
chromosome 4
pacinian
5 alpha reductase deficiency

38. Somatostatin
D cells
hydatidiform mole with crazy high hCG
whats the V/Q at the apex of the lung
placenta previa

39. Bind viral gp41 subunit
fusion inhibitors
3 tumors of MEN 1
Abciximab
granulosa cell tumor secretes what?

40. Alpha synuclein
SE: facial flushing
nucleoside reverse transcriptase inhibitors
sulfonylureas side effect
Lewy bodies composition

41. Estrogen
blocks ADP receptors to inhibit platelet aggregation
master clock for circadian rhythms
G cells
cause of increased myometrial excitability

42. Incomplete fusion of processus vaginalis
GABA - glutamine
S cells
ependymal cells
hydrocele

43. Cant convert testosterone to DHT - ambiguous genitalia until puberty then penis at 12
5 alpha reductase deficiency
branching rods on oral infection
testicular tumor that can present with gynecomastia
vasculitis a/w Hep B

44. Macrophages of the CNS
treatment for SIADH
chief cells
microglia
abruptio placentae

45. Flumazenil
benzos antidote
P450 Inhibitors
3 tumors of MEN 1
hemangioblastomas of retina/cerebellum/medulla

46. Gauchers
most common breast tumor in women under 25
schwann cells
thyroid cancer associtated with RET oncogene
beta glucocerebrosidase

47. Subacute (De Quervain's) thyroiditis
What thyroid pathology has an extremely tender thyroid gland
crinkled paper cytoplasm
Abciximab
most common bacteria in GI tract

48. Regenerates glutathione
What anti - hypertensive drug has the side effect of first dose orthostatic hypotension
may lead to multiple personalities
hemosiderinurea and thrombosis
MofA of N- aceylcysteine

49. Ethosuximide
first line for absence seizures
treatment for SIADH
mildly decreased UDPGT
lysosomal storage disease - demyelinating disease

50. Inhibits platelet aggregation - promotes vasodilation and decreases uterine tone
erythema nodosum
first line for cardiogenic shock
PGI2 (prostacyclin))
most common breast cancer