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USMLE Pathophys

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. G1/S & G2/M
most common breast tumor in women under 25
Addison's
hydatidiform mole with crazy high hCG
what checkpoint is p53 involved with?

2. Criglar Najar
absent UTPGT
gram + bacteria that requires NAD and hemin for growth
lead antidote
most common breast mass in pre - menopausal women

3. Pemphigus vulgaris
What artery causes locked in syndrome
What hormones share a common alpha subunit
anti - epithelial antibodies
Lewy bodies composition

4. Decreased FEV/FVC ratio
sulfonylureas MofA
hallmark sign of COPD
11 beta hydroxylase deficiency
LMN signs

5. Cause release of preformed insulin
alpha 1 anti - trypsin
hydatidiform mole with crazy high hCG
sulfonylureas
t - PA - streptokinase antidote

6. Metachromatic leukodystrophy
lysosomal storage disease - demyelinating disease
etanercept
hemosiderinurea and thrombosis
sclerosing adenosis

7. Oligodendrogila
partial mole components
locus ceruleus
cells destroyed in MS
GFAP positive

8. Glioblastoma multiforme
pseudopalisading necrosis
antibiotic with SE of eosinophilia
SE: elevated LFTS - myositis
sulfonylureas

9. Inner lining of ventricles - make CSF - originate from neuroectoderm
Shigella
ependymal cells
most common breast mass in postmenopausal women
found in hairless skin

10. Choriocarcinoma
tumor composed of cytotrophoblasts and syncytiotrophoblasts
11 beta hydroxylase deficiency
pseudopalisading necrosis
glycine

11. Hereditary spherocytosis
oligohydramnios
most common breast mass in postmenopausal women
increased MCHC and hemolytic anemia
Yolk sac tumor produces...

12. Premature detachment of placenta - painful bleeding in 3rd trimester
abruptio placentae
dorsal motor nucleus
UMN signs
vasculitis a/w Hep B

13. Serous cystadenocarcinoma
most common gyno malignancy
first line for cardiogenic shock
ovarian tumor with psammoma bodies
which nerve lifts the eyelid?

14. Inhibitory in the brain - stimulatory in the brain
pseudopalisading necrosis
GABA - glutamine
corneal clouding & MR
keratin filled cysts

15. Gauchers
3 tumors of MEN 1
crinkled paper cytoplasm
kawasaki
pt has extended expiratory phase

16. A few levels above the level of entry
treatment for SIADH
eczema/recurrent infections/thrombocytopenia
tumor with call - exner bodies
Where does the spinothalamic decussate?

17. Decreased efficacy - decreased Vmax
Schiller Duval bodies
GABA - glutamine
dose response curve with noncompetitive antagonist
BCG PQRS

18. Centriacinar
smoking emphysema
diphtheria treatment
anti - epithelial antibodies
most common primary cardiac tumor in kiddos

19. Autosomal dominant
inheritance pattern for all MENs
sumatriptan
most common lysosomal storage disease
thyroid cancer associtated with RET oncogene

20. Gauchers
beta glucocerebrosidase
myelinates multiple CNS axons
x- linked recessive lysosomal storage diseases
best effect of triglycerides/VLDL

21. Damaged in multiple sclerosis
locus ceruleus
etanercept
oligodendrioglia
pt has extended expiratory phase

22. Macrophages of the CNS
placenta previa
microglia
dermatin sulfate accumulation
beta glucocerebrosidase

23. Papillary
cancer associated with Hashimoto's thyroiditis
thyroid cancer associtated with RET oncogene
tram - track on microscope
medial geniculate nucleus

24. Increases platelet aggregation and vasoconstriction
blood supply for thalamus
inheritance pattern for all MENs
mildly decreased UDPGT
thromboxane A2

25. Incomplete fusion of processus vaginalis
What oncogene is a/w MEN 2a/b
hydatidiform mole with crazy high hCG
hydrocele
eczema/recurrent infections/thrombocytopenia

26. Antibody binds to gp2b/3a - preventing aggregation
silver stain of gram negative rods
Abciximab
supraoptic nucleus of hypothalamus
What are the hormone changes seen in menopause

27. Bruton's agammaglobulinemia
sphingomyelinase deficiency
nucleoside reverse transcriptase inhibitors
defective tyrosine kinase
ventral posterior nucleus - lateral part

28. Oligodendoglia
dermatin sulfate accumulation
sumatriptan
myelinates multiple CNS axons
3 tumors of MEN 1

29. SCID
child with eczema - coarse facial features - cold abscesses
What artery causes locked in syndrome
Abciximab
nucleoside reverse transcriptase inhibitors

30. Somatostatin
D cells
myelinates multiple CNS axons
cells destroyed in MS
sumatriptan

31. 5- fluorouracil
oligodendrioglia
contains ovarian vessels
nucleoside reverse transcriptase inhibitors
thymidylate synthase

32. Kawasaki (treat with high dose aspirin)
catalase negative
Lewy bodies composition
strawberry tongue
meissners

33. Hurlers - Hunters
epithelial
ventral posterior nucleus - medial part
alpha 1 anti - trypsin
dermatin sulfate accumulation

34. Prazosin
What anti - hypertensive drug has the side effect of first dose orthostatic hypotension
gram + bacteria that requires NAD and hemin for growth
chief cells
homer wright rosettes

35. Motor innervation of pharynx - larynx and upper esophagus
colchicine
hep B seropositivity in 30% of patients
order of nerve blockade
ambiguous nucleus

36. Hemangioblastoma
brain tumor a/w von hipple - linadu syndrome
thyroid cancer associtated with RET oncogene
SE: elevated LFTS - myositis
blood supply for thalamus

37. Second most common type of thyroid cancer
alpha galacosidase A
cough - conjunctivitis - coryza - fever
follicular
pacinian

38. Most common type of thyroid cancer
keratin filled cysts
most common lysosomal storage disease
adenomyosis
papillary thyroid cancer

39. Hairless skin - dynamic fine touch
meissners
GFAP positive
LTB4
honey crusted lesions common around nose/lips

40. Complete
parietal cells
x- linked recessive lysosomal storage diseases
hydatidiform mole with crazy high hCG
LMN signs

41. Anxiety - seizures - delirium - life threatening CV collapse
thromboxane A2
opioid withdrawal
barbituates withdrawal
ovarian tumor with psammoma bodies

42. Motor
astrocytes
hallmark sign of COPD
VA/VL
thayer martin media

43. BCG PQRS
P450 inducers
rabies
most common arrthymia
oligohydramnios

44. Makes ADH
basal nucleus of Meynert
supraoptic nucleus of hypothalamus
medial geniculate nucleus
rabies

45. Superchiasmic nucleus
dermatin sulfate accumulation
lisch nodules
master clock for circadian rhythms
D cells

46. Sulfonamides - hydralazine - isonazid - procainamide - phenytoin
What artery causes locked in syndrome
drug induced lupus
anti - platelet antibodies
heparin antidote

47. Combo of inhaled anesthetics & succinylcholine
metformin side effect
cause of malignant hyperthermia
which nerve lifts the eyelid?
low dose ASA effects - intermediate dose - high dose

48. Trichomonas or bacterial vaginosis
SE: facial flushing
treatment for SIADH
cause of high pH vaginal discharge
What oncogene is a/w MEN 2a/b

49. Neurofibromatosis
pt has extended expiratory phase
rate limiting step in carb digestion
lisch nodules
most common arrthymia

50. Decreases platelet aggregation - anti - pyretic and analgesic - high dose is anti - inflammatory
kawasaki
low dose ASA effects - intermediate dose - high dose
dermatin sulfate accumulation
myelinates multiple CNS axons