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USMLE Pathophys

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. TNF receptor
Abciximab
etanercept
What artery causes locked in syndrome
tumor composed of cytotrophoblasts and syncytiotrophoblasts

2. Pepsin
ventral posterior nucleus - lateral part
catalase positive coagulase negative
chief cells
solitarius nucleus

3. Fabry's
lysosomal storage disease a/w renal disease
LMN signs
P450 Inhibitors
eczema/recurrent infections/thrombocytopenia

4. PNH
hemosiderinurea and thrombosis
blocks ADP receptors to inhibit platelet aggregation
branching rods on oral infection
cause of increased myometrial excitability

5. Hemangioblastoma
brain tumor with foamy cells and high vascularity
locus ceruleus
3 tumors of MEN 2a
von Hippel Lindau disease

6. Hunters
mitral valve prolapse - liver diseae - berry aneurysm
myelinates multiple CNS axons
SE: facial flushing
iduronidase sulfatase

7. Tay Sachs
GM2 ganglioside accumulation
Where does the lateral corticospinal decussate?
What are the hormone changes seen in menopause
cause of high pH vaginal discharge

8. Schwann cells
cells destroyed in Guillain Barre
crinkled paper cytoplasm
ovarian tumor that resembles bladder epithelium
parietal cells

9. Choriocarcinoma
tumor composed of cytotrophoblasts and syncytiotrophoblasts
sturge weber syndrome
sulfonylureas MofA
most common breast mass in pre - menopausal women

10. Macconkey's agar
lisch nodules
eczema/recurrent infections/thrombocytopenia
Shigella
most common arrthymia

11. Neurofibromatosis
nucleoside reverse transcriptase inhibitors
dose response curve change with competitive antagonist
brain tumor with psammona bodies
lisch nodules

12. Ependymoma
blocks ADP receptors to inhibit platelet aggregation
granulosa cell tumor secretes what?
brain tumor with perivascular pseudorosettes
paraventricular nucleus of hypothalamus

13. Support - repair - potassium metabolism - remove excess NT - maintain BBB - marker is GFAP
drug that blocks purine synthesis and is metabolized by xanthine oxidase
thymidylate synthase
cause of malignant hyperthermia
astrocytes

14. Deficiency of aldosterone and cortisol

15. Estrogen
ovarian tumor that resembles bladder epithelium
meissners
cause of increased myometrial excitability
anti - platelet antibodies

16. Imabtinib
antibody against philadelphia chromosome
homer wright rosettes
enzyme used to conjugate bilirubin
LTB4

17. Panacinar
cause of high pH vaginal discharge
blocks ADP receptors to inhibit platelet aggregation
alpha 1 anti - trypsin
basal nucleus of Meynert

18. Marfans
floppy mitral valve dissecting aortic aneurysm - berry aneurysm
crinkled paper cytoplasm
What anti - hypertensive drug has the side effect of first dose orthostatic hypotension
branching rods on oral infection

19. Estrogen (causes precocious puberty)
granulosa cell tumor secretes what?
I cells
heparin antidote
What oncogene is a/w MEN 2a/b

20. Sends autonomic fibers to heart
strawberry tongue
dorsal motor nucleus
tram - track on microscope
may lead to multiple personalities

21. Endometrial glands inside myometrium
thayer martin media
What causes coronary vasospasm as a SE?
x- linked recessive lysosomal storage diseases
adenomyosis

22. Small diameter > large diameter; myelinated > unmyelinated
order of nerve blockade
most common bacteria in GI tract
Lateral geniculate nucleus
GABA - glutamine

23. Niemann Pick
sphingomyelinase deficiency
blocks ADP receptors to inhibit platelet aggregation
cause of high pH vaginal discharge
alpha galacosidase A

24. Kawasaki (treat with high dose aspirin)
ventral posterior nucleus - lateral part
hep B seropositivity in 30% of patients
strawberry tongue
What oncogene is a/w MEN 2a/b

25. Chloroquine and primaquine
subluxation of lens
master clock for circadian rhythms
I cells
what meds treat malaria

26. Benign - contains Reinke crystals - usually androgen producing
dose response curve with noncompetitive antagonist
leydig cell tumor
child with partial albinism - peripherial neuropathy - recurrent infections
benzos antidote

27. Ethosuximide
17 alpha hydroxylase deficiency
first line for absence seizures
tram - track on microscope
most common bacteria in GI tract

28. G1/S & G2/M
cancer arising from parafollicular C cells
opioid withdrawal
what checkpoint is p53 involved with?
What oncogene is a/w MEN 2a/b

29. Niacin
iduronidase sulfatase
SE: facial flushing
TZD (glitazones) MofA
resembles an onion in cross section

30. Pacinian
resembles an onion in cross section
What oncogene is a/w MEN 2a/b
smoking emphysema
SE: torsades de pointes

31. Motor
antibody against philadelphia chromosome
VA/VL
follicular
hydatidiform mole with crazy high hCG

32. Serous cystadenocarcinoma
basal nucleus of Meynert
dorsal motor nucleus
ovarian tumor with psammoma bodies
anti - epithelial antibodies

33. Inhibitory in the brain - stimulatory in the brain
master clock for circadian rhythms
GABA - glutamine
t - PA - streptokinase antidote
hydatidiform mole with crazy high hCG

34. Visual (Lateral for Light)
most common breast cancer
Lateral geniculate nucleus
SE: torsades de pointes
GFAP positive

35. D cells of pancreas and gut
what cells secrete somatostatin
3 tumors of MEN 2b
astrocytes
most common breast cancer

36. Protamine sulfate
Bisphosphonates MofA
cancer associated with Hashimoto's thyroiditis
grossly black liver
heparin antidote

37. Gauchers
melanoma tumor marker
G cells
crinkled paper cytoplasm
Shigella

38. Decreased FEV/FVC ratio
P450 inducers
hallmark sign of COPD
most common breast mass in pre - menopausal women
LTB4

39. Primary hyperaldosteronism (HTN - hypokalemia - metabolic alkalosis)

40. Antitoxin - penicillin - DPT vaccine
parietal cells
I cells
diphtheria treatment
supraoptic nucleus of hypothalamus

41. Meningioma
defective tyrosine kinase
brain tumor with psammona bodies
midshaft break of humerus
opioid withdrawal

42. PNH
adenomyosis
hemosiderinurea + thrombosis
locus ceruleus
Addison's

43. Wiscott - Aldrich
eczema/recurrent infections/thrombocytopenia
most common lysosomal storage disease
what meds treat malaria
Aschoff bodies

44. Von Hippel Lindau
smoking emphysema
tram - track on microscope
lewy body composition
hemangioblastomas of retina/cerebellum/medulla

45. Homocystienuria - Marfans
diphtheria treatment
most common lysosomal storage disease
leydig cell tumor
subluxation of lens

46. CCK
ependymal cells
lysosomal storage disease a/w renal disease
cause of increased myometrial excitability
I cells

47. Suspensory ligament of ovaries
contains ovarian vessels
antibody against philadelphia chromosome
meissners
Where does the lateral corticospinal decussate?

48. Pemphigus vulgaris
low dose ASA effects - intermediate dose - high dose
anti - epithelial antibodies
deficiency of mannose phosphorylation
Where does the lateral corticospinal decussate?

49. Second most common type of thyroid cancer
follicular
MofA Levothyroxine
ovarian tumor with psammoma bodies
solitarius nucleus

50. Membranous GN
corneal clouding & MR
spike and dome on microscope
brain tumor with perivascular pseudorosettes
Addison's