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USMLE Pathophys

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Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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1. Invasive ductal
pacinian
UMN signs
chief cells
most common breast cancer

2. Alpha synuclein
raphe nucleus
most common testicular tumor
failure of endodermal development
lewy body composition

3. Fibroadenoma
t - PA - streptokinase antidote
most common breast tumor in women under 25
Yolk sac tumor produces...
UMN signs

4. I- cell disease
astrocytes
order of nerve blockade
deficiency of mannose phosphorylation
melanoma tumor marker

5. Chronic gout. inhibits reabsorbtion of uric acid in PCT
low dose ASA effects - intermediate dose - high dose
probenecid
diphtheria treatment
cause of malignant hyperthermia

6. Pacinian
paraventricular nucleus of hypothalamus
heXosaminidase
resembles an onion in cross section
11 beta hydroxylase deficiency

7. Yolk sac tumor
first line for absence seizures
Schiller Duval bodies
floppy mitral valve dissecting aortic aneurysm - berry aneurysm
papillary thyroid cancer

8. Ret
What oncogene is a/w MEN 2a/b
raphe nucleus
absent UTPGT
brain tumor a/w von hipple - linadu syndrome

9. Ach
3 tumors of MEN 1
ambiguous nucleus
basal nucleus of Meynert
may lead to multiple personalities

10. Benign - contains Reinke crystals - usually androgen producing
locus ceruleus
leydig cell tumor
cause of LH surge
blood supply for thalamus

11. Polyarteritis nodosa
subluxation of lens
hep B seropositivity in 30% of patients
UMN signs
What thyroid pathology has an extremely tender thyroid gland

12. Inhibits viral assembly
protease inhibitors MofA
microglia
iduronidase sulfatase
what inhibits prolactin secretion

13. Causes vasoconstriction (use for acute migraines)
sumatriptan
lisch nodules
whats the V/Q at the apex of the lung
contains ovarian vessels

14. Inhibits osteoclastic activity
partial mole components
Bisphosphonates MofA
paraventricular nucleus of hypothalamus
iduronidase sulfatase

15. Combo of inhaled anesthetics & succinylcholine
cause of malignant hyperthermia
treatment of malignant hyperthermia
follicular
most common gyno malignancy

16. Invasive ductal CA
anti - mitochondrial antibodies
branching rods on oral infection
erythema nodosum
most common breast mass in postmenopausal women

17. Ach
pseudopalisading necrosis
astrocytes
sulfonylureas
basal nucleus of Meynert

18. Macconkey's agar
lewy body composition
homer wright rosettes
cause of increased myometrial excitability
Shigella

19. Second most common type of thyroid cancer
MofA Levothyroxine
complete mole components
follicular
intranuclear inclusions seen in herpes simplex encephalitis

20. Meningioma
brain tumor with psammona bodies
beta glucocerebrosidase
paraventricular nucleus of hypothalamus
metformin side effect

21. Aminocaproic acid
found in hairless skin
t - PA - streptokinase antidote
bocks PRPP synthetase to block purine synthesis
von Hippel Lindau disease

22. Actinomyces
partial mole components
what cells secrete somatostatin
dermatin sulfate accumulation
branching rods on oral infection

23. Cant convert testosterone to DHT - ambiguous genitalia until puberty then penis at 12
11 beta hydroxylase deficiency
plenta accreta
5 alpha reductase deficiency
complete mole components

24. Makes ADH
glycine
supraoptic nucleus of hypothalamus
alpha galacosidase A
3 tumors of MEN 1

25. Hypoglycemia
alpha 1 anti - trypsin
glycine
sulfonylureas side effect
lysosomal storage disease - demyelinating disease

26. Masculinization - hypovolemic shock
most common breast tumor in women under 25
form multinucleated giant cells in the CNS when infected with HIV
low dose ASA effects - intermediate dose - high dose
21 hydroxylase deficiency

27. Medullary
sulfonylureas side effect
cancer arising from parafollicular C cells
ovarian tumor with elevate hCG
sarcoma botyroides

28. Homocystienuria - Marfans
what nerve innervates the muscles of mastication?
subluxation of lens
increased MCHC and hemolytic anemia
schwann cells

29. B. fragilis
ventral posterior nucleus - medial part
which nerve lifts the eyelid?
PTU
most common bacteria in GI tract

30. Lactic acidosis
metformin side effect
alpha galacosidase A
MofA of N- aceylcysteine
most common bacteria in GI tract

31. Increases platelet aggregation and vasoconstriction
neutrophils fail to respond to chemotaxic stimuli
contains ovarian vessels
hep B seropositivity in 30% of patients
thromboxane A2

32. Von Hippel Lindau
whats the V/Q at the apex of the lung
t - PA - streptokinase antidote
hallmark sign of COPD
hemangioblastomas of retina/cerebellum/medulla

33. Polyarteritis nodosa
most common breast mass in postmenopausal women
hemangioblastomas of retina/cerebellum/medulla
vasculitis a/w Hep B
x- linked recessive lysosomal storage diseases

34. ADPKD
mitral valve prolapse - liver diseae - berry aneurysm
inheritance pattern for all MENs
lewy body composition
kluver bucy

35. Panacinar
alpha 1 anti - trypsin
hep B seropositivity in 30% of patients
most common first line agent for septic shock
raphe nucleus

36. 2 sperm + empty egg (no fetal parts)
diphtheria treatment
palisading nuclei - locally invasive
rate limiting step in carb digestion
complete mole components

37. Trigeminal
lysosomal storage disease - demyelinating disease
mildly decreased UDPGT
testicular tumor that can present with gynecomastia
what nerve innervates the muscles of mastication?

38. D cells of pancreas and gut
what cells secrete somatostatin
SE: elevated LFTS - myositis
adenomyosis
melanoma tumor marker

39. Normal or candida
cause of low pH vaginal discharge
blocks ADP receptors to inhibit platelet aggregation
child with partial albinism - peripherial neuropathy - recurrent infections
most common primary cardiac tumor in kiddos

40. HTN - proteinuria - edema
branching rods on oral infection
what nerve innervates the muscles of mastication?
What are the hormone changes seen in menopause
preeclampsia

41. Closes K+ channel on B cells causing depolarization and thus calcium influx which causes insulin release
first line for cardiogenic shock
cause of high pH vaginal discharge
sulfonylureas MofA
what checkpoint is p53 involved with?

42. Subacute (De Quervain's) thyroiditis
What thyroid pathology has an extremely tender thyroid gland
inheritance pattern for all MENs
crinkled paper cytoplasm
most common primary cardiac tumor in kiddos

43. Decreases conversion
order of nerve blockade
lisch nodules
PTU
kluver bucy

44. Job's or LAD
MofA of N- aceylcysteine
LT C4 D4 E4
neutrophils fail to respond to chemotaxic stimuli
dorsal motor nucleus

45. Glutamate
hep B seropositivity in 30% of patients
spike and dome on microscope
tumor composed of cytotrophoblasts and syncytiotrophoblasts
precursor to GABA

46. Function as bronchoconstrictors - vasoconstrictors - sm mm contraction and increased vascular permability
LT C4 D4 E4
cells destroyed in MS
sclerosing adenosis
cells destroyed in Guillain Barre

47. Oculomotor
master clock for circadian rhythms
which nerve lifts the eyelid?
drug that blocks purine synthesis and is metabolized by xanthine oxidase
cancer associated with Hashimoto's thyroiditis

48. Metachromatic leukodystrophy
lysosomal storage disease - demyelinating disease
psammoma bodies
cancer associated with Hashimoto's thyroiditis
microglia

49. Criglar Najar
order of nerve blockade
protease inhibitors MofA
absent UTPGT
sturge weber syndrome

50. Medulla
etanercept
What anti - hypertensive drug has the side effect of first dose orthostatic hypotension
Where does the dorsal column decussate?
whats the V/Q at the apex of the lung

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USMLE Pathophys

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