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USMLE Pathophys

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Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Leydig cell tumor
which nerve lifts the eyelid?
SE: torsades de pointes
testicular tumor that can present with gynecomastia
abruptio placentae

2. Microglia
colchicine
form multinucleated giant cells in the CNS when infected with HIV
fusion inhibitors
thymidylate synthase

3. Streptococcus
adenomyosis
catalase negative
astrocytes
Where does the lateral corticospinal decussate?

4. Cavernous hemangiomas in skin - mucosa & organs; autosomal dominant - a/w renal CA - hemangioblastoma in retina - brainstem & cerebellum
t - PA - streptokinase antidote
kluver bucy
von Hippel Lindau disease
Addison's

5. Negri bodies
rabies
vasculitis of infants and children - involving coronary arteries
hydrocele
17 alpha hydroxylase deficiency

6. Decreased FEV/FVC ratio
vasculitis of infants and children - involving coronary arteries
hallmark sign of COPD
medial geniculate nucleus
hep B seropositivity in 30% of patients

7. Basal cell carcinoma
palisading nuclei - locally invasive
what checkpoint is p53 involved with?
vasculitis of infants and children - involving coronary arteries
S cells

8. Thryroxine replacement
intranuclear inclusions seen in herpes simplex encephalitis
MofA Levothyroxine
treatment of malignant hyperthermia
child with eczema - coarse facial features - cold abscesses

9. A few levels above the level of entry
crinkled paper cytoplasm
Where does the spinothalamic decussate?
brain tumor a/w von hipple - linadu syndrome
what checkpoint is p53 involved with?

10. Rhabdomyoma
colchicine
most common primary cardiac tumor in kiddos
astrocytes
21 hydroxylase deficiency

11. Motor innervation of pharynx - larynx and upper esophagus
ambiguous nucleus
von Hippel Lindau disease
oligohydramnios
contains ovarian vessels

12. Choriocarcinoma
antibody against philadelphia chromosome
tumor composed of cytotrophoblasts and syncytiotrophoblasts
What oncogene is a/w MEN 2a/b
pacinian

13. Aplastic anemia - rash - agranulocytosis
myelinates multiple CNS axons
propylthiouracil side effects
raphe nucleus
barbituates withdrawal

14. Amygdala
vasculitis a/w Hep B
most common breast tumor in women under 25
kluver bucy
3 tumors of MEN 2b

15. Combo of inhaled anesthetics & succinylcholine
brain tumor with perivascular pseudorosettes
rate limiting step in carb digestion
cause of malignant hyperthermia
antibody against philadelphia chromosome

16. Oligodendrogila
cells destroyed in MS
optically clear nuclei (orphan annie)
drug induced lupus
most common breast cancer

17. Medulla
inheritance pattern for all MENs
treatment for SIADH
alpha galacosidase A
Where does the lateral corticospinal decussate?

18. Membranoproliferative GN
schwann cells
hydrocele
thromboxane A2
tram - track on microscope

19. Anxiety - seizures - delirium - life threatening CV collapse
hemangioblastomas of retina/cerebellum/medulla
barbituates withdrawal
propylthiouracil side effects
diphtheria treatment

20. Endometrial CA
form multinucleated giant cells in the CNS when infected with HIV
meissners
Addison's
most common gyno malignancy

21. Kawasaki
dorsal motor nucleus
BCG PQRS
catalase positive coagulase negative
vasculitis of infants and children - involving coronary arteries

22. Alpha feto protein
child with eczema - coarse facial features - cold abscesses
sulfonylureas MofA
Yolk sac tumor produces...
Where does the lateral corticospinal decussate?

23. Penicillamine
tram - track on microscope
which nerve lifts the eyelid?
copper - arsenic - gold antidote
catalase positive coagulase negative

24. Damaged in multiple sclerosis
oligodendrioglia
lisch nodules
3 tumors of MEN 1
thromboxane A2

25. Hurlers
diphtheria treatment
MofA Levothyroxine
most common arrthymia
alpha L iduronidase

26. Gonorrhea
thayer martin media
brain tumor with foamy cells and high vascularity
MofA of N- aceylcysteine
found in hairless skin

27. PNH
What anti - hypertensive drug has the side effect of first dose orthostatic hypotension
sturge weber syndrome
GM2 ganglioside accumulation
hemosiderinurea + thrombosis

28. Protamine sulfate
heparin antidote
abruptio placentae
floppy mitral valve dissecting aortic aneurysm - berry aneurysm
cells destroyed in Guillain Barre

29. Flumazenil
benzos antidote
cancer arising from parafollicular C cells
3 tumors of MEN 2a
chromosome 4

30. Suspensory ligament of ovaries
What are the hormone changes seen in menopause
macrolides use (PUS)
contains ovarian vessels
oligodendrioglia

31. Niacins
best effect on HDL
locus ceruleus
intranuclear inclusions seen in herpes simplex encephalitis
ovarian tumor with psammoma bodies

32. Estrogen
most common breast tumor in women under 25
Galactocerebrosidase deficiency
cause of increased myometrial excitability
cause of malignant hyperthermia

33. Imabtinib
MofA Levothyroxine
What oncogene is a/w MEN 2a/b
antibody against philadelphia chromosome
branching rods on oral infection

34. Staph epidermidis - staph sapro
catalase positive coagulase negative
pacinian
11 beta hydroxylase deficiency
ventral posterior nucleus - lateral part

35. Tay Sachs
cause of LH surge
shown to slow progression of diabetic neuropathy
brain tumor a/w von hipple - linadu syndrome
GM2 ganglioside accumulation

36. Posterior communicating - posterior cerebral - anterior choroidal arteries
opioid withdrawal
blood supply for thalamus
What anti - hypertensive drug has the side effect of first dose orthostatic hypotension
contains ovarian vessels

37. Masculinization - hypovolemic shock
21 hydroxylase deficiency
5 alpha reductase deficiency
which nerve lifts the eyelid?
most common testicular tumor in infants and children up to 3 years of age

38. HTN - proteinuria - edema
preeclampsia
propylthiouracil side effects
what cells secrete somatostatin
cause of LH surge

39. Cause release of preformed insulin
most common first line agent for septic shock
propylthiouracil side effects
meissners
sulfonylureas

40. Decreased potency - increased Km
dose response curve change with competitive antagonist
iduronidase sulfatase
leydig cell tumor
lead antidote

41. Pepsin
chief cells
kluver bucy
strawberry tongue
anti - epithelial antibodies

42. Estrogen
cause of LH surge
11 beta hydroxylase deficiency
colchicine
eczema/recurrent infections/thrombocytopenia

43. Hereditary spherocytosis
glycine
PTU
increased MCHC and hemolytic anemia
currant jelly stool

44. Ethosuximide
first line for absence seizures
basal nucleus of Meynert
vasculitis a/w Hep B
BCG PQRS

45. Measles
brain tumor with fried egg appearance
most common lysosomal storage disease
most common testicular tumor
cough - conjunctivitis - coryza - fever

46. Gilberts
brain tumor with perivascular pseudorosettes
anti - platelet antibodies
mildly decreased UDPGT
most common gyno malignancy

47. Ret
GM2 ganglioside accumulation
What oncogene is a/w MEN 2a/b
partial mole components
grossly black liver

48. Visceral sensory
thromboxane A2
VA/VL
solitarius nucleus
What are the hormone changes seen in menopause

49. Actinomyces
chief cells
looks like fried eggs under histologic staining
smoking emphysema
branching rods on oral infection

50. Inhibits viral assembly
gram + bacteria that requires NAD and hemin for growth
what inhibits prolactin secretion
diphtheria treatment
protease inhibitors MofA

Can you answer 50 questions in 15 minutes?

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USMLE Pathophys

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