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USMLE Pathophys

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Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Damaged in Guillian Barre
antibody against philadelphia chromosome
MofA Levothyroxine
dorsal motor nucleus
schwann cells

2. Endometrial glands inside myometrium
LT C4 D4 E4
UMN signs
found in hairless skin
adenomyosis

3. PPAR- gamma receptor agonist - which causes improved target cell response to insulin
TZD (glitazones) MofA
granulosa cell tumor secretes what?
brenner tumor
honey crusted lesions common around nose/lips

4. Metachromatic leukodystrophy
LT C4 D4 E4
Conn's syndrome
shown to slow progression of diabetic neuropathy
lysosomal storage disease - demyelinating disease

5. Complete
hydatidiform mole with crazy high hCG
SE: facial flushing
anti - platelet antibodies
beta glucocerebrosidase

6. Estrogen
VA/VL
cause of increased myometrial excitability
most common arrthymia
child with eczema - coarse facial features - cold abscesses

7. Auditory (Medial for Music)
medial geniculate nucleus
von Hippel Lindau disease
palisading nuclei - locally invasive
rabies

8. Placenta attached to myometrium
tram - track on microscope
plenta accreta
found in hairless skin
pacinian

9. HTN; masculinization
11 beta hydroxylase deficiency
defective tyrosine kinase
homer wright rosettes
Yolk sac tumor produces...

10. Chediak - Higashi
most common bacteria in GI tract
child with partial albinism - peripherial neuropathy - recurrent infections
leydig cell tumor
sarcoma botyroides

11. Gauchers
locus ceruleus
beta glucocerebrosidase
tumor with call - exner bodies
tumor composed of cytotrophoblasts and syncytiotrophoblasts

12. 0.6
raphe nucleus
rate limiting step in carb digestion
BCG PQRS
whats the V/Q at the base of the lung

13. Aplastic anemia - rash - agranulocytosis
astrocytes
dorsal motor nucleus
schwann cells
propylthiouracil side effects

14. Wiscott - Aldrich
3 tumors of MEN 1
MPTP exposure causes depletion of what NT?
eczema/recurrent infections/thrombocytopenia
hep B seropositivity in 30% of patients

15. Rhabdomyoma
PGI2 (prostacyclin))
most common primary cardiac tumor in kiddos
supraoptic nucleus of hypothalamus
H. flu

16. Astrocytoma & glioblastoma multiforme
cells destroyed in Guillain Barre
lysosomal storage disease - demyelinating disease
GFAP positive
21 hydroxylase deficiency

17. Causes vasoconstriction (use for acute migraines)
mitral valve prolapse - liver diseae - berry aneurysm
GM2 ganglioside accumulation
sumatriptan
tram - track on microscope

18. Alpha synuclein
sturge weber syndrome
ependymal cells
Lewy bodies composition
Conn's syndrome

19. Primary biliary cirrhosis
pseudopalisading necrosis
anti - mitochondrial antibodies
treatment for SIADH
thyroid cancer associtated with RET oncogene

20. Imabtinib
lead antidote
opioid withdrawal
antibody against philadelphia chromosome
cause of low pH vaginal discharge

21. Prevents incorporation into host DNA
hep B seropositivity in 30% of patients
chromosome 4
nucleoside reverse transcriptase inhibitors
Abciximab

22. H. Influenza
master clock for circadian rhythms
propylthiouracil side effects
crinkled paper cytoplasm
gram + bacteria that requires NAD and hemin for growth

23. Cant convert testosterone to DHT - ambiguous genitalia until puberty then penis at 12
antibody against philadelphia chromosome
hep B seropositivity in 30% of patients
ovarian tumor that resembles bladder epithelium
5 alpha reductase deficiency

24. Increased acini and intralobular fibrosis
sclerosing adenosis
vasculitis a/w Hep B
may lead to multiple personalities
PTU

25. Seminoma
most common testicular tumor
locus ceruleus
anti - mitochondrial antibodies
solitarius nucleus

26. Visual (Lateral for Light)
Lateral geniculate nucleus
vasculitis a/w Hep B
3 tumors of MEN 2a
plenta accreta

27. Legionella
hydatidiform mole with crazy high hCG
most common breast tumor in women under 25
silver stain of gram negative rods
what checkpoint is p53 involved with?

28. Rheumatic fever
probenecid
melanoma tumor marker
Aschoff bodies
first line for absence seizures

29. Premature detachment of placenta - painful bleeding in 3rd trimester
abruptio placentae
vasculitis of infants and children - involving coronary arteries
pt has extended expiratory phase
ventral posterior nucleus - lateral part

30. Neutrophil chemotactic agent 'neutrophils arrive B4 others'
locus ceruleus
basal nucleus of Meynert
I cells
LTB4

31. Glioblastoma multiforme
colchicine
brenner tumor
pseudopalisading necrosis
brain tumor a/w von hipple - linadu syndrome

32. Weakness - atrophy - fasiculations - decreased reflexes & tone
looks like fried eggs under histologic staining
LMN signs
child with partial albinism - peripherial neuropathy - recurrent infections
iduronidase sulfatase

33. Oligodendroglia
infliximab
found in hairless skin
looks like fried eggs under histologic staining
what meds treat malaria

34. I- cell disease
infliximab
treatment for SIADH
What oncogene is a/w MEN 2a/b
deficiency of mannose phosphorylation

35. Hairless skin - dynamic fine touch
meissners
defective tyrosine kinase
treatment of malignant hyperthermia
BCG PQRS

36. ADPKD
GABA - glutamine
mitral valve prolapse - liver diseae - berry aneurysm
which nerve lifts the eyelid?
beta glucocerebrosidase

37. Membranous GN
astrocytes
barbituates withdrawal
spike and dome on microscope
adenomyosis

38. Normal or candida
alpha L iduronidase
LT C4 D4 E4
what nerve innervates the muscles of mastication?
cause of low pH vaginal discharge

39. Alpha synuclein
blocks ADP receptors to inhibit platelet aggregation
bocks PRPP synthetase to block purine synthesis
lewy body composition
cough - conjunctivitis - coryza - fever

40. Kawasaki (treat with high dose aspirin)
best effect on HDL
PTU
strawberry tongue
precursor to GABA

41. Inhibits platelet aggregation - promotes vasodilation and decreases uterine tone
first line for cardiogenic shock
PGI2 (prostacyclin))
astrocytes
S cells

42. Inhibits viral assembly
keratin filled cysts
hippocampus
beta glucocerebrosidase
protease inhibitors MofA

43. Benign - contains Reinke crystals - usually androgen producing
shown to slow progression of diabetic neuropathy
leydig cell tumor
dorsal motor nucleus
Galactocerebrosidase deficiency

44. Antitoxin - penicillin - DPT vaccine
locus ceruleus
palisading nuclei - locally invasive
brain tumor with perivascular pseudorosettes
diphtheria treatment

45. Somatostatin
brain tumor a/w von hipple - linadu syndrome
3 tumors of MEN 2b
D cells
BCG PQRS

46. Visceral sensory
myelinates multiple CNS axons
solitarius nucleus
LT C4 D4 E4
x- linked recessive lysosomal storage diseases

47. Deficiency of aldosterone and cortisol

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48. Makes oxytocin
paraventricular nucleus of hypothalamus
whats the V/Q at the base of the lung
enzyme used to conjugate bilirubin
sturge weber syndrome

49. Oligodendrogila
von Hippel Lindau disease
low dose ASA effects - intermediate dose - high dose
cells destroyed in MS
thayer martin media

50. Intussception
parietal cells
currant jelly stool
barbituates withdrawal
most common arrthymia

Can you answer 50 questions in 15 minutes?

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USMLE Pathophys

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