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USMLE Pathophys

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Granulosa cell tumor
tumor with call - exner bodies
most common breast mass in postmenopausal women
lewy body composition
drug that blocks purine synthesis and is metabolized by xanthine oxidase

2. Negri bodies
sulfonylureas side effect
rabies
sarcoma botyroides
vasculitis of infants and children - involving coronary arteries

3. Radial nerve - deep brachial artery
cause of low pH vaginal discharge
x- linked recessive lysosomal storage diseases
midshaft break of humerus
astrocytes

4. Gastrin
G cells
master clock for circadian rhythms
catalase positive coagulase negative
BCG PQRS

5. Depolymerizes microtubules - impairing leukocyte chemotaxis and degranulation
cells destroyed in Guillain Barre
colchicine
cause of malignant hyperthermia
heXosaminidase

6. Pepsin
chief cells
spike and dome on microscope
hydrocele
oligohydramnios

7. Achondroplasia
what cells secrete somatostatin
FGFR3 mutation
low dose ASA effects - intermediate dose - high dose
thyroid cancer associtated with RET oncogene

8. Intussception
first line for cardiogenic shock
hallmark sign of COPD
astrocytes
currant jelly stool

9. Niemann Pick
most common gyno malignancy
currant jelly stool
sphingomyelinase deficiency
blocks ADP receptors to inhibit platelet aggregation

10. Gonorrhea
branching rods on oral infection
supraoptic nucleus of hypothalamus
thayer martin media
probenecid

11. Hurlers - Hunters
ovarian tumor that resembles bladder epithelium
spike and dome on microscope
oligohydramnios
dermatin sulfate accumulation

12. PNH
What artery causes locked in syndrome
order of nerve blockade
hemosiderinurea + thrombosis
fusion inhibitors

13. Rhabdomyoma
locus ceruleus
hemosiderinurea + thrombosis
most common primary cardiac tumor in kiddos
deficiency of mannose phosphorylation

14. Metachromatic leukodystrophy
SICK PEG
colchicine
lysosomal storage disease - demyelinating disease
keratin filled cysts

15. A/w esophageal/duodenal atresia and anencephaly
what nerve innervates the muscles of mastication?
pigmented iris hamartomas - neural tumors
polyhydramnios
psammoma bodies

16. Demeclycocycline or water restriction
alpha L iduronidase
treatment for SIADH
alpha galacosidase A
most common arrthymia

17. B. fragilis
most common arrthymia
found in hairless skin
most common bacteria in GI tract
eczema/recurrent infections/thrombocytopenia

18. Attachment of placenta to lower uterine segment
What anti - hypertensive drug has the side effect of first dose orthostatic hypotension
placenta previa
most common lysosomal storage disease
pseudopalisading necrosis

19. Estrogen (causes precocious puberty)
basal nucleus of Meynert
brain tumor with perivascular pseudorosettes
granulosa cell tumor secretes what?
x- linked recessive lysosomal storage diseases

20. Prazosin
cancer associated with Hashimoto's thyroiditis
UMN signs
What anti - hypertensive drug has the side effect of first dose orthostatic hypotension
crinkled paper cytoplasm

21. Fibrates
oligohydramnios
pseudopalisading necrosis
best effect of triglycerides/VLDL
vasculitis of infants and children - involving coronary arteries

22. Bilateral renal agenesis or posterior urethral valves in males
oligohydramnios
What oncogene is a/w MEN 2a/b
midshaft break of humerus
opioid withdrawal

23. Incomplete fusion of processus vaginalis
vasculitis of infants and children - involving coronary arteries
MofA Levothyroxine
hydrocele
anti - mitochondrial antibodies

24. Fabry's
anti - epithelial antibodies
lysosomal storage disease a/w renal disease
catalase positive coagulase negative
opioid withdrawal

25. Centriacinar
locus ceruleus
sulfonylureas
smoking emphysema
UMN signs

26. Sulfonamides - Isonizid - Cimetidine - Ketoconazole - Erythromyicn - grapefruit juice - protease inhibitors
supraoptic nucleus of hypothalamus
dose response curve with noncompetitive antagonist
alpha galacosidase A
SICK PEG

27. Cause release of preformed insulin
Abciximab
sulfonylureas
neutrophils fail to respond to chemotaxic stimuli
propylthiouracil side effects

28. Basal cell carcinoma
H. flu
palisading nuclei - locally invasive
order of nerve blockade
MPTP exposure causes depletion of what NT?

29. Leydig cell tumor
thyroid cancer associtated with RET oncogene
testicular tumor that can present with gynecomastia
LMN signs
astrocytes

30. NF 1
Abciximab
pigmented iris hamartomas - neural tumors
pt has extended expiratory phase
colchicine

31. Impetigo
honey crusted lesions common around nose/lips
pt has extended expiratory phase
Bisphosphonates MofA
dose response curve change with competitive antagonist

32. Papillary CA of thyroid
tumor composed of cytotrophoblasts and syncytiotrophoblasts
astrocytes
optically clear nuclei (orphan annie)
SICK PEG

33. Inner lining of ventricles - make CSF - originate from neuroectoderm
ependymal cells
rate limiting step in carb digestion
what meds treat malaria
myelinates on PNS

34. Papillary
Galactocerebrosidase deficiency
rate limiting step in carb digestion
drug that blocks purine synthesis and is metabolized by xanthine oxidase
thyroid cancer associtated with RET oncogene

35. Oculomotor
which nerve lifts the eyelid?
ovarian tumor that resembles bladder epithelium
metformin side effect
testicular tumor that can present with gynecomastia

36. Fibroadenoma
catalase positive coagulase negative
most common breast tumor in women under 25
hydatidiform mole with crazy high hCG
locus ceruleus

37. 2 sperm + empty egg (no fetal parts)
Bisphosphonates MofA
complete mole components
pigmented iris hamartomas - neural tumors
sclerosing adenosis

38. Sulfonamides - hydralazine - isonazid - procainamide - phenytoin
drug induced lupus
lewy body composition
whats the V/Q at the base of the lung
most common protozoal infection in US

39. Ovarian bengin tumor...looks like bladder
brenner tumor
What causes coronary vasospasm as a SE?
MofA of N- aceylcysteine
kluver bucy

40. Alpha feto protein
complete mole components
cough - conjunctivitis - coryza - fever
Yolk sac tumor produces...
enzyme used to conjugate bilirubin

41. Anxiety - insomnia - sweating - dilated pupils - piloerection - rhinorrhea
opioid withdrawal
spike and dome on microscope
3 tumors of MEN 1
what meds treat malaria

42. ITP
sturge weber syndrome
nucleoside reverse transcriptase inhibitors
treatment for SIADH
anti - platelet antibodies

43. Medulla
Where does the dorsal column decussate?
cause of low pH vaginal discharge
absent UTPGT
hydrocele

44. 0.6
what inhibits prolactin secretion
hydrocele
whats the V/Q at the base of the lung
most common gyno malignancy

45. Macrolides
hemosiderinurea and thrombosis
child with eczema - coarse facial features - cold abscesses
What anti - hypertensive drug has the side effect of first dose orthostatic hypotension
antibiotic with SE of eosinophilia

46. Makes ADH
supraoptic nucleus of hypothalamus
silver stain of gram negative rods
5 alpha reductase deficiency
ventral posterior nucleus - medial part

47. Vaginal carcinoma: spindle shaped tumor cells that are desmin positive
precursor to GABA
sarcoma botyroides
paraventricular nucleus of hypothalamus
most common lysosomal storage disease

48. Ach
cough - conjunctivitis - coryza - fever
whats the V/Q at the apex of the lung
SE: torsades de pointes
basal nucleus of Meynert

49. Criglar Najar
catalase positive coagulase negative
treatment for SIADH
most common breast tumor in women under 25
absent UTPGT

50. Gauchers
infliximab
hemosiderinurea and thrombosis
beta glucocerebrosidase
x- linked recessive lysosomal storage diseases