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USMLE Pathophys

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Panacinar
Yolk sac tumor produces...
locus ceruleus
supraoptic nucleus of hypothalamus
alpha 1 anti - trypsin

2. Memory
which nerve lifts the eyelid?
Galactocerebrosidase deficiency
hippocampus
erythema nodosum

3. Hunters
spike and dome on microscope
P450 Inhibitors
iduronidase sulfatase
blood supply for thalamus

4. DiGeorge
grossly black liver
most common primary cardiac tumor in kiddos
opioids antidote
failure of endodermal development

5. Membranoproliferative GN
treatment for SIADH
dorsal motor nucleus
tram - track on microscope
dose response curve change with competitive antagonist

6. Decreased follicles & estrogen with increased FSH & LH
epithelial
increased MCHC and hemolytic anemia
What are the hormone changes seen in menopause
hydatidiform mole with crazy high hCG

7. Gauchers
LTB4
most common lysosomal storage disease
kawasaki
papillary thyroid cancer

8. Sotalol - quinidine - cisapride
tumor with call - exner bodies
SE: torsades de pointes
SE: elevated LFTS - myositis
G cells

9. Amygdala
cause of LH surge
metformin side effect
infliximab
kluver bucy

10. Fibrates
tram - track on microscope
best effect of triglycerides/VLDL
anti - mitochondrial antibodies
currant jelly stool

11. BCG PQRS
P450 inducers
tram - track on microscope
propylthiouracil side effects
What causes coronary vasospasm as a SE?

12. Dubin Johnson
tumor with call - exner bodies
hemosiderinurea + thrombosis
heXosaminidase
grossly black liver

13. Increases platelet aggregation and vasoconstriction
contains ovarian vessels
thromboxane A2
most common protozoal infection in US
Lateral geniculate nucleus

14. Alpha synuclein
Lewy bodies composition
what checkpoint is p53 involved with?
anti - mitochondrial antibodies
sulfonylureas MofA

15. Oligodendrioma
MofA of N- aceylcysteine
hippocampus
most common breast mass in postmenopausal women
brain tumor with fried egg appearance

16. Benign - contains Reinke crystals - usually androgen producing
oligohydramnios
leydig cell tumor
tumor with call - exner bodies
tumor composed of cytotrophoblasts and syncytiotrophoblasts

17. NE
deficiency of mannose phosphorylation
locus ceruleus
catalase negative
precursor to GABA

18. Incomplete fusion of processus vaginalis
alpha galacosidase A
dose response curve change with competitive antagonist
hydrocele
parietal cells

19. Decreased FEV/FVC ratio
SE: facial flushing
hallmark sign of COPD
astrocytes
optically clear nuclei (orphan annie)

20. H. Influenza
lisch nodules
sturge weber syndrome
basal nucleus of Meynert
gram + bacteria that requires NAD and hemin for growth

21. Decreases conversion
PTU
What anti - hypertensive drug has the side effect of first dose orthostatic hypotension
neutrophils fail to respond to chemotaxic stimuli
mitral valve prolapse - liver diseae - berry aneurysm

22. Suspensory ligament of ovaries
ventral posterior nucleus - lateral part
floppy mitral valve dissecting aortic aneurysm - berry aneurysm
Lateral geniculate nucleus
contains ovarian vessels

23. D cells of pancreas and gut
GFAP positive
macrolides use (PUS)
blood supply for thalamus
what cells secrete somatostatin

24. Actinomyces
brenner tumor
GM2 ganglioside accumulation
which nerve lifts the eyelid?
branching rods on oral infection

25. Serotonin
oligohydramnios
neutrophils fail to respond to chemotaxic stimuli
raphe nucleus
MPTP exposure causes depletion of what NT?

26. Bromocriptine
kluver bucy
pacinian
pt has extended expiratory phase
what inhibits prolactin secretion

27. Ethosuximide
branching rods on oral infection
ventral posterior nucleus - lateral part
first line for absence seizures
lysosomal storage disease - demyelinating disease

28. Flumazenil
benzos antidote
honey crusted lesions common around nose/lips
pigmented iris hamartomas - neural tumors
ventral posterior nucleus - medial part

29. Streptococcus
P450 Inhibitors
G cells
myelinates multiple CNS axons
catalase negative

30. Atrial fibrillation
UMN signs
grossly black liver
most common arrthymia
dermatin sulfate accumulation

31. Protamine sulfate
child with partial albinism - peripherial neuropathy - recurrent infections
heparin antidote
infliximab
Abciximab

32. 6- mecaptopurine (metabolized by xanthine oxidase)
what meds treat malaria
thyroid cancer associtated with RET oncogene
probenecid
bocks PRPP synthetase to block purine synthesis

33. Inhibits platelet aggregation - promotes vasodilation and decreases uterine tone
what cells secrete somatostatin
PGI2 (prostacyclin))
brenner tumor
cancer associated with Hashimoto's thyroiditis

34. Motor innervation of pharynx - larynx and upper esophagus
alpha galacosidase A
most common gyno malignancy
ambiguous nucleus
homer wright rosettes

35. Bind viral gp41 subunit
fusion inhibitors
iduronidase sulfatase
alpha galacosidase A
most common breast cancer

36. Prevents incorporation into host DNA
sumatriptan
beta glucocerebrosidase
nucleoside reverse transcriptase inhibitors
catalase positive coagulase negative

37. B. fragilis
tumor with call - exner bodies
Galactocerebrosidase deficiency
eczema/recurrent infections/thrombocytopenia
most common bacteria in GI tract

38. Homocystienuria - Marfans
Where does the dorsal column decussate?
subluxation of lens
keratin filled cysts
blocks ADP receptors to inhibit platelet aggregation

39. Actinomyces
dose response curve with noncompetitive antagonist
granulosa cell tumor secretes what?
branching rods on oral infection
kluver bucy

40. Babinski - weakness - increased reflexes & tone - spastic paralysis
Shigella
UMN signs
MPTP exposure causes depletion of what NT?
3 tumors of MEN 2a

41. Meningioma
blood supply for thalamus
ventral posterior nucleus - lateral part
brain tumor with psammona bodies
benzos antidote

42. Glioblastoma multiforme
pseudopalisading necrosis
what inhibits prolactin secretion
VA/VL
resembles an onion in cross section

43. Imabtinib
oligodendrioglia
antibody against philadelphia chromosome
kluver bucy
FGFR3 mutation

44. Marfans
What hormones share a common alpha subunit
paraventricular nucleus of hypothalamus
ovarian tumor that resembles bladder epithelium
floppy mitral valve dissecting aortic aneurysm - berry aneurysm

45. Combo of inhaled anesthetics & succinylcholine
cause of malignant hyperthermia
pigmented iris hamartomas - neural tumors
currant jelly stool
ventral posterior nucleus - lateral part

46. A few levels above the level of entry
Where does the spinothalamic decussate?
contains ovarian vessels
lewy body composition
diphtheria treatment

47. Fibrocystic
Lateral geniculate nucleus
most common breast mass in pre - menopausal women
brain tumor with fried egg appearance
hydatidiform mole with crazy high hCG

48. Antibody binds to gp2b/3a - preventing aggregation
VA/VL
plenta accreta
Abciximab
most common testicular tumor in infants and children up to 3 years of age

49. Criglar Najar
absent UTPGT
cause of malignant hyperthermia
benzos antidote
thayer martin media

50. TSH - LH - FSH - hCG
21 hydroxylase deficiency
GABA - glutamine
ambiguous nucleus
What hormones share a common alpha subunit