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USMLE Pathophys

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Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. 5- fluorouracil
VA/VL
brain tumor with psammona bodies
thymidylate synthase
21 hydroxylase deficiency

2. Choriocarcinoma or dysgerminoma
increased MCHC and hemolytic anemia
MofA of N- aceylcysteine
ovarian tumor with elevate hCG
heparin antidote

3. I- cell disease
vasculitis of infants and children - involving coronary arteries
MPTP exposure causes depletion of what NT?
oligohydramnios
deficiency of mannose phosphorylation

4. Port wine stains - ipsilateral leptomeningeal angioma; can cause glaucoma - seizures - hemipareis - and MR
PTU
enzyme used to conjugate bilirubin
sturge weber syndrome
found in hairless skin

5. Seminoma
PGI2 (prostacyclin))
I cells
most common testicular tumor
homer wright rosettes

6. Inhibits viral assembly
which nerve lifts the eyelid?
protease inhibitors MofA
what cells secrete somatostatin
precursor to GABA

7. Serous cystadenocarcinoma
ovarian tumor with psammoma bodies
oligodendrioglia
beta glucocerebrosidase
Where does the lateral corticospinal decussate?

8. Decreased FEV/FVC ratio
beta glucocerebrosidase
hallmark sign of COPD
treatment of malignant hyperthermia
Aschoff bodies

9. Alpha synuclein
locus ceruleus
Where does the dorsal column decussate?
lewy body composition
palisading nuclei - locally invasive

10. Auditory (Medial for Music)
What thyroid pathology has an extremely tender thyroid gland
most common protozoal infection in US
what meds treat malaria
medial geniculate nucleus

11. Medulla
basal nucleus of Meynert
Where does the lateral corticospinal decussate?
most common first line agent for septic shock
5 alpha reductase deficiency

12. Actinomyces
copper - arsenic - gold antidote
branching rods on oral infection
palisading nuclei - locally invasive
ambiguous nucleus

13. Schwann cells
x- linked recessive lysosomal storage diseases
rate limiting step in carb digestion
myelinates on PNS
heXosaminidase

14. Decreases conversion
homer wright rosettes
cancer associated with Hashimoto's thyroiditis
PTU
Where does the spinothalamic decussate?

15. Inflammatory lesions of subq fat - usually on anterior shins. a/w infections
schwann cells
GFAP positive
erythema nodosum
S cells

16. Chocolate agar
corneal clouding & MR
parietal cells
LMN signs
H. flu

17. Trichomonas or bacterial vaginosis
cause of high pH vaginal discharge
hippocampus
sclerosing adenosis
lysosomal storage disease - demyelinating disease

18. Oligosaccaride hydrolase
rate limiting step in carb digestion
D cells
What thyroid pathology has an extremely tender thyroid gland
thayer martin media

19. Oligodendrogila
copper - arsenic - gold antidote
contains ovarian vessels
MPTP exposure causes depletion of what NT?
cells destroyed in MS

20. Body sensation
ventral posterior nucleus - lateral part
most common arrthymia
raphe nucleus
sulfonylureas MofA

21. Invasive ductal CA
most common breast mass in postmenopausal women
epithelial
11 beta hydroxylase deficiency
GM2 ganglioside accumulation

22. Macrolides
oligohydramnios
PGI2 (prostacyclin))
antibiotic with SE of eosinophilia
astrocytes

23. Glioblastoma multiforme
H. flu
SE: elevated LFTS - myositis
alpha galacosidase A
pseudopalisading necrosis

24. Increased acini and intralobular fibrosis
granulosa cell tumor secretes what?
found in hairless skin
form multinucleated giant cells in the CNS when infected with HIV
sclerosing adenosis

25. BCG PQRS
antibiotic with SE of eosinophilia
strawberry tongue
P450 inducers
most common breast mass in postmenopausal women

26. Papillary
increased MCHC and hemolytic anemia
treatment of malignant hyperthermia
parietal cells
thyroid cancer associtated with RET oncogene

27. Schwann cells
Conn's syndrome
cells destroyed in Guillain Barre
brain tumor a/w von hipple - linadu syndrome
heparin antidote

28. NE
chromosome 4
ovarian tumor with elevate hCG
PGI2 (prostacyclin))
locus ceruleus

29. Streptococcus
failure of endodermal development
catalase negative
3 tumors of MEN 1
complete mole components

30. Normal or candida
barbituates withdrawal
ovarian tumor with elevate hCG
dermatin sulfate accumulation
cause of low pH vaginal discharge

31. Granulosa cell tumor
21 hydroxylase deficiency
tumor with call - exner bodies
increased MCHC and hemolytic anemia
antibiotic with SE of eosinophilia

32. Yolk sac tumor
P450 inducers
Schiller Duval bodies
mitral valve prolapse - liver diseae - berry aneurysm
LT C4 D4 E4

33. HTN - proteinuria - edema
raphe nucleus
brain tumor with perivascular pseudorosettes
preeclampsia
meissners

34. Combo of inhaled anesthetics & succinylcholine
Galactocerebrosidase deficiency
alpha 1 anti - trypsin
cause of malignant hyperthermia
smoking emphysema

35. PNH
partial mole components
hemosiderinurea and thrombosis
anti - platelet antibodies
brain tumor with fried egg appearance

36. Fibrates
rabies
partial mole components
vasculitis of infants and children - involving coronary arteries
best effect of triglycerides/VLDL

37. Norepinephrine
child with eczema - coarse facial features - cold abscesses
What anti - hypertensive drug has the side effect of first dose orthostatic hypotension
locus ceruleus
grossly black liver

38. Atrial fibrillation
What anti - hypertensive drug has the side effect of first dose orthostatic hypotension
P450 Inhibitors
most common arrthymia
Schiller Duval bodies

39. Suspensory ligament of ovaries
dose response curve change with competitive antagonist
paraventricular nucleus of hypothalamus
bocks PRPP synthetase to block purine synthesis
contains ovarian vessels

40. Trichomonas - Giardia
child with eczema - coarse facial features - cold abscesses
most common protozoal infection in US
5 alpha reductase deficiency
catalase positive coagulase negative

41. Attachment of placenta to lower uterine segment
D cells
locus ceruleus
cause of increased myometrial excitability
placenta previa

42. Krabbe's
Bisphosphonates MofA
Galactocerebrosidase deficiency
Where does the spinothalamic decussate?
raphe nucleus

43. Inhibitory in the SC
most common first line agent for septic shock
MofA of N- aceylcysteine
glycine
medial geniculate nucleus

44. Marfans
what cells secrete somatostatin
paraventricular nucleus of hypothalamus
spike and dome on microscope
floppy mitral valve dissecting aortic aneurysm - berry aneurysm

45. Fabrys
form multinucleated giant cells in the CNS when infected with HIV
sphingomyelinase deficiency
alpha galacosidase A
GABA - glutamine

46. Anti - TNF antibody - use for RA but watch out for latent TB!
most common testicular tumor
cause of malignant hyperthermia
hep B seropositivity in 30% of patients
infliximab

47. Estrogen
solitarius nucleus
silver stain of gram negative rods
cause of increased myometrial excitability
complete mole components

48. Parathyroid - pituitary - pancreatic
psammoma bodies
pseudopalisading necrosis
intranuclear inclusions seen in herpes simplex encephalitis
3 tumors of MEN 1

49. G1/S & G2/M
chief cells
placenta previa
what checkpoint is p53 involved with?
MofA Levothyroxine

50. Centriacinar
What anti - hypertensive drug has the side effect of first dose orthostatic hypotension
smoking emphysema
treatment of malignant hyperthermia
most common breast cancer

Can you answer 50 questions in 15 minutes?

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USMLE Pathophys

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