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USMLE Pathophys

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Sotalol - quinidine - cisapride
solitarius nucleus
SE: torsades de pointes
PTU
testicular tumor that can present with gynecomastia

2. Dimercaprol
form multinucleated giant cells in the CNS when infected with HIV
treatment for SIADH
lead antidote
Galactocerebrosidase deficiency

3. Pemphigus vulgaris
best effect on HDL
brain tumor a/w von hipple - linadu syndrome
5 alpha reductase deficiency
anti - epithelial antibodies

4. Port wine stains - ipsilateral leptomeningeal angioma; can cause glaucoma - seizures - hemipareis - and MR
LMN signs
HELLP syndrome
ventral posterior nucleus - medial part
sturge weber syndrome

5. Increases platelet aggregation and vasoconstriction
cancer arising from parafollicular C cells
thromboxane A2
chief cells
heparin antidote

6. Seminoma
may lead to multiple personalities
corneal clouding & MR
glycine
most common testicular tumor

7. Actinomyces
branching rods on oral infection
colchicine
brain tumor with perivascular pseudorosettes
crinkled paper cytoplasm

8. Primary hyperaldosteronism (HTN - hypokalemia - metabolic alkalosis)

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9. Oligodendrogila
oligodendrioglia
most common breast tumor in women under 25
cells destroyed in MS
FGFR3 mutation

10. Legionella
low dose ASA effects - intermediate dose - high dose
What are the hormone changes seen in menopause
silver stain of gram negative rods
cause of increased myometrial excitability

11. Causes vasoconstriction (use for acute migraines)
alpha galacosidase A
11 beta hydroxylase deficiency
sumatriptan
resembles an onion in cross section

12. Chloroquine and primaquine
may lead to multiple personalities
supraoptic nucleus of hypothalamus
thayer martin media
what meds treat malaria

13. 3
etanercept
chief cells
looks like fried eggs under histologic staining
whats the V/Q at the apex of the lung

14. Dobutamine
lead antidote
which nerve lifts the eyelid?
most common bacteria in GI tract
first line for cardiogenic shock

15. Cell type involved in most ovarian tumors
epithelial
polyhydramnios
kawasaki
most common primary cardiac tumor in kiddos

16. SCID
abruptio placentae
branching rods on oral infection
child with eczema - coarse facial features - cold abscesses
hydatidiform mole with crazy high hCG

17. Small diameter > large diameter; myelinated > unmyelinated
order of nerve blockade
what inhibits prolactin secretion
testicular tumor that can present with gynecomastia
strawberry tongue

18. Closes K+ channel on B cells causing depolarization and thus calcium influx which causes insulin release
sulfonylureas MofA
best effect on HDL
lysosomal storage disease - demyelinating disease
anti - platelet antibodies

19. Radial nerve - deep brachial artery
first line for cardiogenic shock
midshaft break of humerus
hallmark sign of COPD
erythema nodosum

20. Fibrocystic
most common breast mass in pre - menopausal women
defective tyrosine kinase
locus ceruleus
adenomyosis

21. Medullary
placenta previa
cancer arising from parafollicular C cells
chief cells
precursor to GABA

22. Serotonin
t - PA - streptokinase antidote
lysosomal storage disease a/w renal disease
sulfonylureas MofA
raphe nucleus

23. Macrophages of the CNS
thyroid cancer associtated with RET oncogene
Where does the dorsal column decussate?
microglia
ventral posterior nucleus - medial part

24. PPAR- gamma receptor agonist - which causes improved target cell response to insulin
most common breast mass in pre - menopausal women
t - PA - streptokinase antidote
TZD (glitazones) MofA
midshaft break of humerus

25. PNH
ependymal cells
plenta accreta
anti - platelet antibodies
hemosiderinurea and thrombosis

26. Schwann cells
lysosomal storage disease a/w renal disease
branching rods on oral infection
SE: facial flushing
cells destroyed in Guillain Barre

27. Visual (Lateral for Light)
whats the V/Q at the apex of the lung
low dose ASA effects - intermediate dose - high dose
Lateral geniculate nucleus
opioid withdrawal

28. Function as bronchoconstrictors - vasoconstrictors - sm mm contraction and increased vascular permability
LT C4 D4 E4
antibiotic with SE of eosinophilia
lead antidote
etanercept

29. Bromocriptine
what inhibits prolactin secretion
cause of malignant hyperthermia
catalase positive coagulase negative
I cells

30. Hurlers
corneal clouding & MR
master clock for circadian rhythms
branching rods on oral infection
blood supply for thalamus

31. Papillary CA of thyroid
dose response curve with noncompetitive antagonist
optically clear nuclei (orphan annie)
MofA of N- aceylcysteine
basal nucleus of Meynert

32. Dubin Johnson
first line for cardiogenic shock
grossly black liver
MPTP exposure causes depletion of what NT?
Lateral geniculate nucleus

33. Ethosuximide
first line for absence seizures
Yolk sac tumor produces...
spike and dome on microscope
absent UTPGT

34. Choriocarcinoma
child with eczema - coarse facial features - cold abscesses
tumor composed of cytotrophoblasts and syncytiotrophoblasts
I cells
pigmented iris hamartomas - neural tumors

35. Amygdala
vasculitis a/w Hep B
kluver bucy
keratin filled cysts
Lateral geniculate nucleus

36. Yolk sac
neutrophils fail to respond to chemotaxic stimuli
most common testicular tumor in infants and children up to 3 years of age
partial mole components
etanercept

37. Antibody binds to gp2b/3a - preventing aggregation
PTU
parietal cells
Abciximab
dorsal motor nucleus

38. Motor innervation of pharynx - larynx and upper esophagus
ambiguous nucleus
honey crusted lesions common around nose/lips
paraventricular nucleus of hypothalamus
lewy body composition

39. Metachromatic leukodystrophy
cause of LH surge
intranuclear inclusions seen in herpes simplex encephalitis
meissners
lysosomal storage disease - demyelinating disease

40. Krabbe's
psammoma bodies
Galactocerebrosidase deficiency
SICK PEG
opioids antidote

41. Papillary CA of thyroid - meningioma - mesothelioma - serous cystadenocarcinoma of ovary
alpha galacosidase A
hemosiderinurea and thrombosis
psammoma bodies
sclerosing adenosis

42. Inner lining of ventricles - make CSF - originate from neuroectoderm
MPTP exposure causes depletion of what NT?
sumatriptan
ependymal cells
G cells

43. Bruton's agammaglobulinemia
defective tyrosine kinase
locus ceruleus
Galactocerebrosidase deficiency
dorsal motor nucleus

44. Hemangioblastoma
pt has extended expiratory phase
drug that blocks purine synthesis and is metabolized by xanthine oxidase
brain tumor a/w von hipple - linadu syndrome
astrocytes

45. Sulfonamides - Isonizid - Cimetidine - Ketoconazole - Erythromyicn - grapefruit juice - protease inhibitors
absent UTPGT
what nerve innervates the muscles of mastication?
most common breast cancer
SICK PEG

46. A/w esophageal/duodenal atresia and anencephaly
Bisphosphonates MofA
polyhydramnios
strawberry tongue
subluxation of lens

47. Naloxone/naltrexone
astrocytes
what checkpoint is p53 involved with?
opioids antidote
honey crusted lesions common around nose/lips

48. Hurlers
Lewy bodies composition
best effect of triglycerides/VLDL
Shigella
alpha L iduronidase

49. Hemolysis - elevated LFTs - Low Platelets
HELLP syndrome
PTU
papillary thyroid cancer
ventral posterior nucleus - medial part

50. Body sensation
thyroid cancer associtated with RET oncogene
oligodendrioglia
ventral posterior nucleus - lateral part
most common primary cardiac tumor in kiddos