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USMLE Pathophys

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Niacin
ovarian tumor with elevate hCG
SE: facial flushing
first line for absence seizures
propylthiouracil side effects

2. Masculinization - hypovolemic shock
21 hydroxylase deficiency
currant jelly stool
polyhydramnios
rate limiting step in carb digestion

3. Anxiety - seizures - delirium - life threatening CV collapse
barbituates withdrawal
astrocytes
most common bacteria in GI tract
pseudopalisading necrosis

4. Bromocriptine
first line for cardiogenic shock
vasculitis a/w Hep B
macrolides use (PUS)
what inhibits prolactin secretion

5. Sulfonamides - Isonizid - Cimetidine - Ketoconazole - Erythromyicn - grapefruit juice - protease inhibitors
ventral posterior nucleus - lateral part
SICK PEG
treatment of malignant hyperthermia
sturge weber syndrome

6. Centriacinar
t - PA - streptokinase antidote
silver stain of gram negative rods
smoking emphysema
anti - platelet antibodies

7. Gauchers
crinkled paper cytoplasm
what nerve innervates the muscles of mastication?
t - PA - streptokinase antidote
sulfonylureas MofA

8. Obstructive - COPD
pigmented iris hamartomas - neural tumors
what cells secrete somatostatin
low dose ASA effects - intermediate dose - high dose
pt has extended expiratory phase

9. Anxiety - insomnia - sweating - dilated pupils - piloerection - rhinorrhea
most common first line agent for septic shock
What hormones share a common alpha subunit
What anti - hypertensive drug has the side effect of first dose orthostatic hypotension
opioid withdrawal

10. Amygdala
probenecid
kluver bucy
brain tumor with fried egg appearance
What anti - hypertensive drug has the side effect of first dose orthostatic hypotension

11. Prazosin
mildly decreased UDPGT
raphe nucleus
What anti - hypertensive drug has the side effect of first dose orthostatic hypotension
brain tumor with fried egg appearance

12. Fabry's & Hunters
thyroid cancer associtated with RET oncogene
x- linked recessive lysosomal storage diseases
hydrocele
MofA Levothyroxine

13. 2 sperm + empty egg (no fetal parts)
complete mole components
alpha galacosidase A
most common first line agent for septic shock
brain tumor with psammona bodies

14. Tay SaX
thromboxane A2
anti - epithelial antibodies
smoking emphysema
heXosaminidase

15. Inhibits osteoclastic activity
vasculitis of infants and children - involving coronary arteries
colchicine
Bisphosphonates MofA
most common testicular tumor in infants and children up to 3 years of age

16. Medulloblastoma
meissners
homer wright rosettes
catalase negative
most common bacteria in GI tract

17. Decreases conversion
what nerve innervates the muscles of mastication?
pt has extended expiratory phase
tumor composed of cytotrophoblasts and syncytiotrophoblasts
PTU

18. Ret
What oncogene is a/w MEN 2a/b
thymidylate synthase
myelinates on PNS
catalase positive coagulase negative

19. ADPKD
mitral valve prolapse - liver diseae - berry aneurysm
cough - conjunctivitis - coryza - fever
pseudopalisading necrosis
alpha L iduronidase

20. Oculomotor
precursor to GABA
ventral posterior nucleus - lateral part
cough - conjunctivitis - coryza - fever
which nerve lifts the eyelid?

21. Fabry's
lysosomal storage disease a/w renal disease
tumor composed of cytotrophoblasts and syncytiotrophoblasts
paraventricular nucleus of hypothalamus
grossly black liver

22. Serotonin
What hormones share a common alpha subunit
locus ceruleus
most common breast cancer
raphe nucleus

23. Kawasaki (treat with high dose aspirin)
PTU
SE: facial flushing
brain tumor with foamy cells and high vascularity
strawberry tongue

24. Pneumonia - URIs - STDS
ependymal cells
x- linked recessive lysosomal storage diseases
P450 inducers
macrolides use (PUS)

25. Facial sensation (Make up on your face)
schwann cells
ventral posterior nucleus - medial part
Bisphosphonates MofA
Schiller Duval bodies

26. Hurlers - Hunters
pigmented iris hamartomas - neural tumors
MofA of N- aceylcysteine
whats the V/Q at the base of the lung
dermatin sulfate accumulation

27. Intrinsic factor
drug induced lupus
resembles an onion in cross section
parietal cells
keratin filled cysts

28. Estrogen (causes precocious puberty)
granulosa cell tumor secretes what?
cancer associated with Hashimoto's thyroiditis
dorsal motor nucleus
partial mole components

29. 0.6
x- linked recessive lysosomal storage diseases
brain tumor with fried egg appearance
best effect on HDL
whats the V/Q at the base of the lung

30. Alpha synuclein
lewy body composition
cause of high pH vaginal discharge
may lead to multiple personalities
GFAP positive

31. Neutrophil chemotactic agent 'neutrophils arrive B4 others'
LTB4
heparin antidote
granulosa cell tumor secretes what?
partial mole components

32. Inner lining of ventricles - make CSF - originate from neuroectoderm
What thyroid pathology has an extremely tender thyroid gland
ependymal cells
macrolides use (PUS)
hippocampus

33. Body sensation
ventral posterior nucleus - lateral part
probenecid
what nerve innervates the muscles of mastication?
heXosaminidase

34. Macrolides
crinkled paper cytoplasm
antibiotic with SE of eosinophilia
hemosiderinurea + thrombosis
corneal clouding & MR

35. Lactic acidosis
GABA - glutamine
What anti - hypertensive drug has the side effect of first dose orthostatic hypotension
metformin side effect
anti - platelet antibodies

36. NF 1
deficiency of mannose phosphorylation
pigmented iris hamartomas - neural tumors
21 hydroxylase deficiency
GM2 ganglioside accumulation

37. Lymphoma

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38. Autosomal dominant
cells destroyed in Guillain Barre
anti - mitochondrial antibodies
inheritance pattern for all MENs
thyroid cancer associtated with RET oncogene

39. Sends autonomic fibers to heart
dorsal motor nucleus
ambiguous nucleus
What hormones share a common alpha subunit
enzyme used to conjugate bilirubin

40. Prevents incorporation into host DNA
thromboxane A2
sphingomyelinase deficiency
nucleoside reverse transcriptase inhibitors
failure of endodermal development

41. Niemann Pick
sphingomyelinase deficiency
macrolides use (PUS)
precursor to GABA
brain tumor with perivascular pseudorosettes

42. Naloxone/naltrexone
raphe nucleus
opioids antidote
solitarius nucleus
eczema/recurrent infections/thrombocytopenia

43. Norepinephrine
cancer arising from parafollicular C cells
master clock for circadian rhythms
most common first line agent for septic shock
locus ceruleus

44. Fibrates/statins
basal nucleus of Meynert
SE: elevated LFTS - myositis
cough - conjunctivitis - coryza - fever
sphingomyelinase deficiency

45. Port wine stains - ipsilateral leptomeningeal angioma; can cause glaucoma - seizures - hemipareis - and MR
which nerve lifts the eyelid?
sturge weber syndrome
colchicine
supraoptic nucleus of hypothalamus

46. BCG PQRS
what inhibits prolactin secretion
von Hippel Lindau disease
resembles an onion in cross section
P450 inducers

47. Alpha synuclein
currant jelly stool
Lewy bodies composition
nucleoside reverse transcriptase inhibitors
master clock for circadian rhythms

48. Damaged in multiple sclerosis
oligodendrioglia
UMN signs
thyroid cancer associtated with RET oncogene
heparin antidote

49. Glucuronyl transferase
may lead to multiple personalities
hemosiderinurea + thrombosis
iduronidase sulfatase
enzyme used to conjugate bilirubin

50. Endometrial glands inside myometrium
adenomyosis
sarcoma botyroides
anti - epithelial antibodies
opioids antidote