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USMLE Pathophys

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Facial sensation (Make up on your face)
ventral posterior nucleus - medial part
macrolides use (PUS)
gram + bacteria that requires NAD and hemin for growth
complete mole components

2. Ret
What oncogene is a/w MEN 2a/b
most common breast cancer
What causes coronary vasospasm as a SE?
SICK PEG

3. Serous cystadenocarcinoma
etanercept
ovarian tumor with psammoma bodies
cancer arising from parafollicular C cells
ependymal cells

4. Chloroquine and primaquine
what meds treat malaria
best effect of triglycerides/VLDL
LT C4 D4 E4
hemosiderinurea + thrombosis

5. Alpha feto protein
Yolk sac tumor produces...
erythema nodosum
cancer arising from parafollicular C cells
currant jelly stool

6. Thryroxine replacement
antibody against philadelphia chromosome
corneal clouding & MR
most common gyno malignancy
MofA Levothyroxine

7. Ethosuximide
first line for absence seizures
heparin antidote
macrolides use (PUS)
propylthiouracil side effects

8. Auditory (Medial for Music)
medial geniculate nucleus
sulfonylureas
testicular tumor that can present with gynecomastia
ovarian tumor that resembles bladder epithelium

9. Cocain and sumatriptan
What causes coronary vasospasm as a SE?
child with partial albinism - peripherial neuropathy - recurrent infections
GABA - glutamine
sulfonylureas

10. Estrogen
most common breast tumor in women under 25
cause of increased myometrial excitability
ventral posterior nucleus - medial part
Bisphosphonates MofA

11. Secretin
S cells
astrocytes
21 hydroxylase deficiency
Where does the lateral corticospinal decussate?

12. Radial nerve - deep brachial artery
microglia
basal nucleus of Meynert
catalase positive coagulase negative
midshaft break of humerus

13. Subacute (De Quervain's) thyroiditis
cells destroyed in Guillain Barre
optically clear nuclei (orphan annie)
astrocytes
What thyroid pathology has an extremely tender thyroid gland

14. Support - repair - potassium metabolism - remove excess NT - maintain BBB - marker is GFAP
which nerve lifts the eyelid?
paraventricular nucleus of hypothalamus
astrocytes
best effect on HDL

15. PNH
hemosiderinurea and thrombosis
first line for absence seizures
Galactocerebrosidase deficiency
What hormones share a common alpha subunit

16. Dantrolene (prevents release of calcium from SR of muscle)
What causes coronary vasospasm as a SE?
oligodendrioglia
most common testicular tumor
treatment of malignant hyperthermia

17. 2 sperm + empty egg (no fetal parts)
hemosiderinurea and thrombosis
lewy body composition
complete mole components
What are the hormone changes seen in menopause

18. Oligodendroglia
looks like fried eggs under histologic staining
astrocytes
plenta accreta
blocks ADP receptors to inhibit platelet aggregation

19. Tay SaX
heXosaminidase
sulfonylureas side effect
diphtheria treatment
lysosomal storage disease a/w renal disease

20. Astrocytoma & glioblastoma multiforme
adenomyosis
pt has extended expiratory phase
GFAP positive
shown to slow progression of diabetic neuropathy

21. Seborric keratosis
Addison's
honey crusted lesions common around nose/lips
anti - mitochondrial antibodies
keratin filled cysts

22. TNF receptor
etanercept
D cells
Where does the dorsal column decussate?
whats the V/Q at the apex of the lung

23. Glucuronyl transferase
most common arrthymia
enzyme used to conjugate bilirubin
basal nucleus of Meynert
PGI2 (prostacyclin))

24. Decreased FEV/FVC ratio
smoking emphysema
hallmark sign of COPD
hep B seropositivity in 30% of patients
basal nucleus of Meynert

25. Antitoxin - penicillin - DPT vaccine
vasculitis of infants and children - involving coronary arteries
diphtheria treatment
opioid withdrawal
What thyroid pathology has an extremely tender thyroid gland

26. Brenners tumor
ovarian tumor that resembles bladder epithelium
brain tumor with fried egg appearance
keratin filled cysts
best effect on HDL

27. Decreased efficacy - decreased Vmax
dose response curve with noncompetitive antagonist
D cells
hydrocele
ambiguous nucleus

28. Fibrocystic
raphe nucleus
dose response curve change with competitive antagonist
most common breast mass in pre - menopausal women
preeclampsia

29. Medulla
Where does the dorsal column decussate?
cause of malignant hyperthermia
x- linked recessive lysosomal storage diseases
deficiency of mannose phosphorylation

30. Gilberts
most common lysosomal storage disease
mildly decreased UDPGT
palisading nuclei - locally invasive
What hormones share a common alpha subunit

31. CCK
metformin side effect
nucleoside reverse transcriptase inhibitors
D cells
I cells

32. Motor innervation of pharynx - larynx and upper esophagus
absent UTPGT
raphe nucleus
ambiguous nucleus
opioid withdrawal

33. Normal or candida
cause of low pH vaginal discharge
floppy mitral valve dissecting aortic aneurysm - berry aneurysm
colchicine
child with eczema - coarse facial features - cold abscesses

34. Vibration - pressure
anti - platelet antibodies
BCG PQRS
pacinian
sturge weber syndrome

35. Glioblastoma multiforme
pseudopalisading necrosis
What are the hormone changes seen in menopause
currant jelly stool
iduronidase sulfatase

36. Dopamine
GM2 ganglioside accumulation
MPTP exposure causes depletion of what NT?
increased MCHC and hemolytic anemia
LTB4

37. ACE inhibitors
thromboxane A2
what inhibits prolactin secretion
cause of increased myometrial excitability
shown to slow progression of diabetic neuropathy

38. Hereditary spherocytosis
anti - platelet antibodies
heparin antidote
increased MCHC and hemolytic anemia
what nerve innervates the muscles of mastication?

39. Ach
supraoptic nucleus of hypothalamus
brain tumor with perivascular pseudorosettes
sphingomyelinase deficiency
basal nucleus of Meynert

40. Staph epidermidis - staph sapro
catalase positive coagulase negative
3 tumors of MEN 2a
alpha galacosidase A
diphtheria treatment

41. Clopidogrel - ticoplidine
alpha L iduronidase
sulfonylureas MofA
blocks ADP receptors to inhibit platelet aggregation
most common testicular tumor

42. 5- fluorouracil
SE: elevated LFTS - myositis
colchicine
brain tumor with foamy cells and high vascularity
thymidylate synthase

43. Lactic acidosis
etanercept
cancer arising from parafollicular C cells
metformin side effect
infliximab

44. Prevents incorporation into host DNA
order of nerve blockade
nucleoside reverse transcriptase inhibitors
placenta previa
basal nucleus of Meynert

45. Actinomyces
hallmark sign of COPD
branching rods on oral infection
sumatriptan
propylthiouracil side effects

46. Inflammatory lesions of subq fat - usually on anterior shins. a/w infections
currant jelly stool
astrocytes
order of nerve blockade
erythema nodosum

47. SCID
form multinucleated giant cells in the CNS when infected with HIV
etanercept
deficiency of mannose phosphorylation
child with eczema - coarse facial features - cold abscesses

48. Rheumatic fever
grossly black liver
Aschoff bodies
basal nucleus of Meynert
parietal cells

49. Dubin Johnson
palisading nuclei - locally invasive
grossly black liver
keratin filled cysts
medial geniculate nucleus

50. Makes ADH
most common breast cancer
supraoptic nucleus of hypothalamus
most common breast tumor in women under 25
most common protozoal infection in US