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USMLE Pathophys

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Ethosuximide
most common primary cardiac tumor in kiddos
erythema nodosum
first line for absence seizures
x- linked recessive lysosomal storage diseases

2. Hunters
copper - arsenic - gold antidote
child with partial albinism - peripherial neuropathy - recurrent infections
Lateral geniculate nucleus
iduronidase sulfatase

3. Trichomonas or bacterial vaginosis
most common protozoal infection in US
most common arrthymia
cause of high pH vaginal discharge
thayer martin media

4. Oligodendrioma
x- linked recessive lysosomal storage diseases
most common bacteria in GI tract
brain tumor with fried egg appearance
thromboxane A2

5. Babinski - weakness - increased reflexes & tone - spastic paralysis
UMN signs
eczema/recurrent infections/thrombocytopenia
silver stain of gram negative rods
Where does the lateral corticospinal decussate?

6. Imabtinib
antibody against philadelphia chromosome
fusion inhibitors
macrolides use (PUS)
silver stain of gram negative rods

7. 5- fluorouracil
most common primary cardiac tumor in kiddos
thymidylate synthase
SE: torsades de pointes
crinkled paper cytoplasm

8. Cause release of preformed insulin
follicular
sulfonylureas
FGFR3 mutation
palisading nuclei - locally invasive

9. Tay Sachs
GM2 ganglioside accumulation
benzos antidote
testicular tumor that can present with gynecomastia
mitral valve prolapse - liver diseae - berry aneurysm

10. Membranoproliferative GN
Where does the lateral corticospinal decussate?
HELLP syndrome
17 alpha hydroxylase deficiency
tram - track on microscope

11. Pacinian
resembles an onion in cross section
most common breast cancer
rate limiting step in carb digestion
cells destroyed in MS

12. Marfans
floppy mitral valve dissecting aortic aneurysm - berry aneurysm
sulfonylureas MofA
raphe nucleus
mitral valve prolapse - liver diseae - berry aneurysm

13. Decreased efficacy - decreased Vmax
neutrophils fail to respond to chemotaxic stimuli
dose response curve with noncompetitive antagonist
basal nucleus of Meynert
cells destroyed in MS

14. Medulla
low dose ASA effects - intermediate dose - high dose
contains ovarian vessels
Where does the dorsal column decussate?
VA/VL

15. Membranous GN
palisading nuclei - locally invasive
cough - conjunctivitis - coryza - fever
Conn's syndrome
spike and dome on microscope

16. Papillary CA of thyroid - meningioma - mesothelioma - serous cystadenocarcinoma of ovary
tram - track on microscope
anti - epithelial antibodies
psammoma bodies
Addison's

17. Sulfonamides - Isonizid - Cimetidine - Ketoconazole - Erythromyicn - grapefruit juice - protease inhibitors
SICK PEG
treatment of malignant hyperthermia
paraventricular nucleus of hypothalamus
lysosomal storage disease a/w renal disease

18. Rheumatic fever
hemosiderinurea and thrombosis
order of nerve blockade
testicular tumor that can present with gynecomastia
Aschoff bodies

19. Anxiety - insomnia - sweating - dilated pupils - piloerection - rhinorrhea
propylthiouracil side effects
opioid withdrawal
What are the hormone changes seen in menopause
Where does the lateral corticospinal decussate?

20. 3
LTB4
ovarian tumor that resembles bladder epithelium
drug induced lupus
whats the V/Q at the apex of the lung

21. Fibroadenoma
LT C4 D4 E4
most common breast tumor in women under 25
best effect on HDL
polyhydramnios

22. Hairless skin - dynamic fine touch
hydrocele
brain tumor with perivascular pseudorosettes
meissners
blood supply for thalamus

23. Penicillamine
polyhydramnios
silver stain of gram negative rods
copper - arsenic - gold antidote
partial mole components

24. Hemangioblastoma
follicular
Galactocerebrosidase deficiency
lead antidote
brain tumor a/w von hipple - linadu syndrome

25. Microglia
form multinucleated giant cells in the CNS when infected with HIV
corneal clouding & MR
drug induced lupus
What hormones share a common alpha subunit

26. Obstructive - COPD
testicular tumor that can present with gynecomastia
pt has extended expiratory phase
mildly decreased UDPGT
kluver bucy

27. DiGeorge
failure of endodermal development
HELLP syndrome
parietal cells
psammoma bodies

28. Anti - TNF antibody - use for RA but watch out for latent TB!
leydig cell tumor
increased MCHC and hemolytic anemia
midshaft break of humerus
infliximab

29. Alpha feto protein
Yolk sac tumor produces...
gram + bacteria that requires NAD and hemin for growth
3 tumors of MEN 2b
brain tumor with perivascular pseudorosettes

30. Panacinar
complete mole components
floppy mitral valve dissecting aortic aneurysm - berry aneurysm
SE: elevated LFTS - myositis
alpha 1 anti - trypsin

31. Increases platelet aggregation and vasoconstriction
most common testicular tumor in infants and children up to 3 years of age
oligohydramnios
thromboxane A2
iduronidase sulfatase

32. Hypoglycemia
sulfonylureas side effect
most common testicular tumor in infants and children up to 3 years of age
may lead to multiple personalities
heXosaminidase

33. Endometrial glands inside myometrium
locus ceruleus
first line for absence seizures
adenomyosis
benzos antidote

34. Medullary thyroid - pheochromocytoma - parathryoid
cancer arising from parafollicular C cells
3 tumors of MEN 2a
most common breast mass in pre - menopausal women
lysosomal storage disease a/w renal disease

35. HTN; XY will be a girl - XX will lack secondary sex char.
paraventricular nucleus of hypothalamus
17 alpha hydroxylase deficiency
ependymal cells
Aschoff bodies

36. Inhibits platelet aggregation - promotes vasodilation and decreases uterine tone
t - PA - streptokinase antidote
LT C4 D4 E4
VA/VL
PGI2 (prostacyclin))

37. Clopidogrel - ticoplidine
drug induced lupus
blocks ADP receptors to inhibit platelet aggregation
erythema nodosum
Shigella

38. S-100
Addison's
melanoma tumor marker
most common breast mass in pre - menopausal women
hemosiderinurea + thrombosis

39. 6- mecaptopurine (metabolized by xanthine oxidase)
what meds treat malaria
found in hairless skin
bocks PRPP synthetase to block purine synthesis
glycine

40. Cowdry type A inclusions
bocks PRPP synthetase to block purine synthesis
abruptio placentae
intranuclear inclusions seen in herpes simplex encephalitis
What hormones share a common alpha subunit

41. Fibrocystic
most common breast mass in pre - menopausal women
cancer arising from parafollicular C cells
kawasaki
first line for cardiogenic shock

42. Gastrin
found in hairless skin
G cells
whats the V/Q at the apex of the lung
tumor composed of cytotrophoblasts and syncytiotrophoblasts

43. Ependymoma
hemangioblastomas of retina/cerebellum/medulla
brain tumor with perivascular pseudorosettes
Conn's syndrome
sclerosing adenosis

44. Papillary CA of thyroid
optically clear nuclei (orphan annie)
sulfonylureas side effect
cells destroyed in MS
I cells

45. Amygdala
kluver bucy
most common primary cardiac tumor in kiddos
whats the V/Q at the base of the lung
most common testicular tumor in infants and children up to 3 years of age

46. Dissociative
inheritance pattern for all MENs
may lead to multiple personalities
glycine
most common primary cardiac tumor in kiddos

47. Memory
blocks ADP receptors to inhibit platelet aggregation
strawberry tongue
What oncogene is a/w MEN 2a/b
hippocampus

48. Ovarian bengin tumor...looks like bladder
PGI2 (prostacyclin))
t - PA - streptokinase antidote
brenner tumor
what nerve innervates the muscles of mastication?

49. Facial sensation (Make up on your face)
whats the V/Q at the base of the lung
thyroid cancer associtated with RET oncogene
ventral posterior nucleus - medial part
G cells

50. Choriocarcinoma
partial mole components
brain tumor a/w von hipple - linadu syndrome
tumor composed of cytotrophoblasts and syncytiotrophoblasts
dorsal motor nucleus