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USMLE Pathophys

Instructions:

Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Ach
basal nucleus of Meynert
cause of high pH vaginal discharge
most common first line agent for septic shock
mitral valve prolapse - liver diseae - berry aneurysm

2. Fibrocystic
testicular tumor that can present with gynecomastia
brain tumor with perivascular pseudorosettes
hippocampus
most common breast mass in pre - menopausal women

3. Anxiety - seizures - delirium - life threatening CV collapse
glycine
Lateral geniculate nucleus
best effect on HDL
barbituates withdrawal

4. Increases platelet aggregation and vasoconstriction
adenomyosis
copper - arsenic - gold antidote
whats the V/Q at the apex of the lung
thromboxane A2

5. Polyarteritis nodosa
hep B seropositivity in 30% of patients
etanercept
looks like fried eggs under histologic staining
rate limiting step in carb digestion

6. Estrogen
MofA Levothyroxine
whats the V/Q at the base of the lung
fusion inhibitors
cause of increased myometrial excitability

7. Hemangioblastoma
form multinucleated giant cells in the CNS when infected with HIV
brain tumor with foamy cells and high vascularity
low dose ASA effects - intermediate dose - high dose
heXosaminidase

8. Alpha synuclein
which nerve lifts the eyelid?
erythema nodosum
cells destroyed in MS
Lewy bodies composition

9. Medulla
hippocampus
hep B seropositivity in 30% of patients
Where does the lateral corticospinal decussate?
What are the hormone changes seen in menopause

10. Bruton's agammaglobulinemia
sclerosing adenosis
defective tyrosine kinase
SICK PEG
crinkled paper cytoplasm

11. Measles
lisch nodules
Shigella
cough - conjunctivitis - coryza - fever
locus ceruleus

12. Serous cystadenocarcinoma
What oncogene is a/w MEN 2a/b
first line for absence seizures
What thyroid pathology has an extremely tender thyroid gland
ovarian tumor with psammoma bodies

13. Macrophages of the CNS
neutrophils fail to respond to chemotaxic stimuli
locus ceruleus
nucleoside reverse transcriptase inhibitors
microglia

14. Sends autonomic fibers to heart
ovarian tumor with elevate hCG
sarcoma botyroides
lysosomal storage disease - demyelinating disease
dorsal motor nucleus

15. Premature detachment of placenta - painful bleeding in 3rd trimester
floppy mitral valve dissecting aortic aneurysm - berry aneurysm
ventral posterior nucleus - lateral part
H. flu
abruptio placentae

16. Hairless skin - dynamic fine touch
LMN signs
3 tumors of MEN 2a
meissners
opioid withdrawal

17. Posterior communicating - posterior cerebral - anterior choroidal arteries
palisading nuclei - locally invasive
MofA of N- aceylcysteine
thyroid cancer associtated with RET oncogene
blood supply for thalamus

18. Ret
vasculitis a/w Hep B
gram + bacteria that requires NAD and hemin for growth
What oncogene is a/w MEN 2a/b
kluver bucy

19. Rheumatic fever
opioids antidote
Aschoff bodies
found in hairless skin
most common breast mass in postmenopausal women

20. Cocain and sumatriptan
looks like fried eggs under histologic staining
What causes coronary vasospasm as a SE?
leydig cell tumor
vasculitis of infants and children - involving coronary arteries

21. NF 1
brain tumor with foamy cells and high vascularity
pigmented iris hamartomas - neural tumors
granulosa cell tumor secretes what?
what meds treat malaria

22. Somatostatin
enzyme used to conjugate bilirubin
best effect on HDL
D cells
optically clear nuclei (orphan annie)

23. Decreased follicles & estrogen with increased FSH & LH
hydatidiform mole with crazy high hCG
erythema nodosum
What are the hormone changes seen in menopause
drug that blocks purine synthesis and is metabolized by xanthine oxidase

24. Sulfonamides - Isonizid - Cimetidine - Ketoconazole - Erythromyicn - grapefruit juice - protease inhibitors
inheritance pattern for all MENs
copper - arsenic - gold antidote
brain tumor with foamy cells and high vascularity
SICK PEG

25. Niacin
Bisphosphonates MofA
hemosiderinurea and thrombosis
H. flu
SE: facial flushing

26. Ethosuximide
branching rods on oral infection
palisading nuclei - locally invasive
dose response curve with noncompetitive antagonist
first line for absence seizures

27. Niemann Pick
grossly black liver
basal nucleus of Meynert
sphingomyelinase deficiency
floppy mitral valve dissecting aortic aneurysm - berry aneurysm

28. Kawasaki (treat with high dose aspirin)
which nerve lifts the eyelid?
What hormones share a common alpha subunit
sarcoma botyroides
strawberry tongue

29. Papillary
adenomyosis
precursor to GABA
alpha 1 anti - trypsin
thyroid cancer associtated with RET oncogene

30. Most common type of thyroid cancer
papillary thyroid cancer
dose response curve change with competitive antagonist
SE: elevated LFTS - myositis
dorsal motor nucleus

31. Ovarian bengin tumor...looks like bladder
low dose ASA effects - intermediate dose - high dose
brenner tumor
kluver bucy
MofA of N- aceylcysteine

32. Wiscott - Aldrich
polyhydramnios
eczema/recurrent infections/thrombocytopenia
cause of malignant hyperthermia
dose response curve change with competitive antagonist

33. Invasive ductal CA
benzos antidote
hemosiderinurea and thrombosis
most common breast mass in postmenopausal women
increased MCHC and hemolytic anemia

34. Job's or LAD
neutrophils fail to respond to chemotaxic stimuli
21 hydroxylase deficiency
strawberry tongue
eczema/recurrent infections/thrombocytopenia

35. Decreased potency - increased Km
paraventricular nucleus of hypothalamus
dose response curve change with competitive antagonist
rate limiting step in carb digestion
Where does the dorsal column decussate?

36. B. fragilis
most common bacteria in GI tract
FGFR3 mutation
what nerve innervates the muscles of mastication?
chromosome 4

37. Glucuronyl transferase
PTU
metformin side effect
enzyme used to conjugate bilirubin
ovarian tumor with elevate hCG

38. Motor
LMN signs
VA/VL
solitarius nucleus
Where does the lateral corticospinal decussate?

39. Medulloblastoma
cause of malignant hyperthermia
what meds treat malaria
GM2 ganglioside accumulation
homer wright rosettes

40. Actinomyces
macrolides use (PUS)
branching rods on oral infection
catalase negative
MPTP exposure causes depletion of what NT?

41. Neurofibromatosis
hemangioblastomas of retina/cerebellum/medulla
P450 Inhibitors
cancer arising from parafollicular C cells
lisch nodules

42. Sotalol - quinidine - cisapride
most common primary cardiac tumor in kiddos
Conn's syndrome
optically clear nuclei (orphan annie)
SE: torsades de pointes

43. Cells of BBB
astrocytes
optically clear nuclei (orphan annie)
plenta accreta
most common lysosomal storage disease

44. A few levels above the level of entry
Where does the spinothalamic decussate?
hippocampus
most common primary cardiac tumor in kiddos
follicular

45. HTN - proteinuria - edema
parietal cells
preeclampsia
opioid withdrawal
Yolk sac tumor produces...

46. Dobutamine
Yolk sac tumor produces...
subluxation of lens
UMN signs
first line for cardiogenic shock

47. Seborric keratosis
keratin filled cysts
von Hippel Lindau disease
GM2 ganglioside accumulation
lysosomal storage disease - demyelinating disease

48. Gauchers
Aschoff bodies
placenta previa
D cells
beta glucocerebrosidase

49. Polyarteritis nodosa
treatment of malignant hyperthermia
vasculitis a/w Hep B
What artery causes locked in syndrome
may lead to multiple personalities

50. Oligodendroglia
looks like fried eggs under histologic staining
sturge weber syndrome
3 tumors of MEN 2b
precursor to GABA