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USMLE Pathophys

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Answer 50 questions in 15 minutes.
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Match each statement with the correct term.
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1. Mucocutaneous lymph node syndrome - necrotizing vasculitis - coronary aneurysms - strawberry tongue
cough - conjunctivitis - coryza - fever
kawasaki
intranuclear inclusions seen in herpes simplex encephalitis
beta glucocerebrosidase

2. Regenerates glutathione
MofA of N- aceylcysteine
papillary thyroid cancer
opioid withdrawal
psammoma bodies

3. Hemolysis - elevated LFTs - Low Platelets
lysosomal storage disease - demyelinating disease
hemosiderinurea + thrombosis
HELLP syndrome
astrocytes

4. Dubin Johnson
myelinates multiple CNS axons
grossly black liver
Where does the spinothalamic decussate?
neutrophils fail to respond to chemotaxic stimuli

5. Astrocytoma & glioblastoma multiforme
hydatidiform mole with crazy high hCG
sarcoma botyroides
GFAP positive
what inhibits prolactin secretion

6. Actinomyces
antibody against philadelphia chromosome
branching rods on oral infection
propylthiouracil side effects
catalase positive coagulase negative

7. Yolk sac
cancer arising from parafollicular C cells
ventral posterior nucleus - lateral part
brain tumor a/w von hipple - linadu syndrome
most common testicular tumor in infants and children up to 3 years of age

8. HTN; XY will be a girl - XX will lack secondary sex char.
17 alpha hydroxylase deficiency
most common first line agent for septic shock
TZD (glitazones) MofA
t - PA - streptokinase antidote

9. Atrial fibrillation
dose response curve with noncompetitive antagonist
best effect on HDL
most common arrthymia
order of nerve blockade

10. Amygdala
sulfonylureas MofA
LTB4
kluver bucy
sumatriptan

11. NF 1
locus ceruleus
polyhydramnios
most common gyno malignancy
pigmented iris hamartomas - neural tumors

12. Dantrolene (prevents release of calcium from SR of muscle)
kluver bucy
inheritance pattern for all MENs
looks like fried eggs under histologic staining
treatment of malignant hyperthermia

13. 2 sperm + 1 egg (fetal parts present)
polyhydramnios
Galactocerebrosidase deficiency
sulfonylureas side effect
partial mole components

14. S-100
melanoma tumor marker
cough - conjunctivitis - coryza - fever
17 alpha hydroxylase deficiency
thyroid cancer associtated with RET oncogene

15. DiGeorge
kawasaki
hep B seropositivity in 30% of patients
VA/VL
failure of endodermal development

16. Clopidogrel - ticoplidine
alpha galacosidase A
thayer martin media
gram + bacteria that requires NAD and hemin for growth
blocks ADP receptors to inhibit platelet aggregation

17. HTN - proteinuria - edema
copper - arsenic - gold antidote
cells destroyed in MS
preeclampsia
found in hairless skin

18. Lymphoma

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19. Membranoproliferative GN
paraventricular nucleus of hypothalamus
cough - conjunctivitis - coryza - fever
melanoma tumor marker
tram - track on microscope

20. 0.6
whats the V/Q at the base of the lung
von Hippel Lindau disease
most common breast mass in pre - menopausal women
best effect on HDL

21. Von Hippel Lindau
hemangioblastomas of retina/cerebellum/medulla
most common breast cancer
antibody against philadelphia chromosome
What oncogene is a/w MEN 2a/b

22. Niemann Pick
adenomyosis
leydig cell tumor
sphingomyelinase deficiency
mitral valve prolapse - liver diseae - berry aneurysm

23. Masculinization - hypovolemic shock
5 alpha reductase deficiency
21 hydroxylase deficiency
locus ceruleus
astrocytes

24. Anxiety - insomnia - sweating - dilated pupils - piloerection - rhinorrhea
opioid withdrawal
cancer associated with Hashimoto's thyroiditis
anti - mitochondrial antibodies
pacinian

25. Fibrates
best effect of triglycerides/VLDL
TZD (glitazones) MofA
precursor to GABA
VA/VL

26. Oligodendoglia
supraoptic nucleus of hypothalamus
PTU
benzos antidote
myelinates multiple CNS axons

27. Panacinar
alpha 1 anti - trypsin
smoking emphysema
ovarian tumor with elevate hCG
alpha galacosidase A

28. Hurlers
lewy body composition
Where does the spinothalamic decussate?
ovarian tumor that resembles bladder epithelium
alpha L iduronidase

29. Facial sensation (Make up on your face)
drug that blocks purine synthesis and is metabolized by xanthine oxidase
ventral posterior nucleus - medial part
3 tumors of MEN 2b
Yolk sac tumor produces...

30. Microglia
thromboxane A2
LT C4 D4 E4
form multinucleated giant cells in the CNS when infected with HIV
palisading nuclei - locally invasive

31. Hurlers - Hunters
supraoptic nucleus of hypothalamus
subluxation of lens
dermatin sulfate accumulation
dose response curve change with competitive antagonist

32. Lactic acidosis
metformin side effect
cells destroyed in Guillain Barre
D cells
ependymal cells

33. Schwann cells
psammoma bodies
3 tumors of MEN 2a
cancer arising from parafollicular C cells
myelinates on PNS

34. Measles
order of nerve blockade
erythema nodosum
cough - conjunctivitis - coryza - fever
most common breast cancer

35. Meningioma
G cells
brain tumor with psammona bodies
brenner tumor
defective tyrosine kinase

36. H. Influenza
cancer arising from parafollicular C cells
gram + bacteria that requires NAD and hemin for growth
LTB4
neutrophils fail to respond to chemotaxic stimuli

37. Incomplete fusion of processus vaginalis
blocks ADP receptors to inhibit platelet aggregation
whats the V/Q at the base of the lung
best effect on HDL
hydrocele

38. Premature detachment of placenta - painful bleeding in 3rd trimester
palisading nuclei - locally invasive
shown to slow progression of diabetic neuropathy
abruptio placentae
t - PA - streptokinase antidote

39. Fabry's & Hunters
ovarian tumor with elevate hCG
x- linked recessive lysosomal storage diseases
antibody against philadelphia chromosome
myelinates multiple CNS axons

40. Suspensory ligament of ovaries
I cells
gram + bacteria that requires NAD and hemin for growth
contains ovarian vessels
leydig cell tumor

41. Medullary
etanercept
tumor composed of cytotrophoblasts and syncytiotrophoblasts
UMN signs
cancer arising from parafollicular C cells

42. Imabtinib
antibody against philadelphia chromosome
astrocytes
H. flu
x- linked recessive lysosomal storage diseases

43. NE
dose response curve with noncompetitive antagonist
eczema/recurrent infections/thrombocytopenia
Where does the spinothalamic decussate?
most common first line agent for septic shock

44. Rhabdomyoma
Where does the spinothalamic decussate?
most common primary cardiac tumor in kiddos
smoking emphysema
fusion inhibitors

45. Damaged in Guillian Barre
schwann cells
most common arrthymia
hep B seropositivity in 30% of patients
catalase negative

46. Penicillamine
lysosomal storage disease a/w renal disease
brain tumor with foamy cells and high vascularity
copper - arsenic - gold antidote
midshaft break of humerus

47. Macconkey's agar
Shigella
basal nucleus of Meynert
PTU
mitral valve prolapse - liver diseae - berry aneurysm

48. 6- MP
cells destroyed in Guillain Barre
oligohydramnios
failure of endodermal development
drug that blocks purine synthesis and is metabolized by xanthine oxidase

49. Huntingtons chorea
chromosome 4
pacinian
SICK PEG
tumor with call - exner bodies

50. Aminocaproic acid
t - PA - streptokinase antidote
mildly decreased UDPGT
alpha galacosidase A
form multinucleated giant cells in the CNS when infected with HIV

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USMLE Pathophys

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