Test your basic knowledge |

USMLE Step 1 First Aid Pathology

Instructions:
  • Answer 50 questions in 15 minutes.
  • If you are not ready to take this test, you can study here.
  • Match each statement with the correct term.
  • Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. tumor: Follicular and undifferentiated lymphomas (inhibits apoptosis) What is the associated oncogene?






2. Paraneoplastic effects of tumors: Thymoma - small cell lung carcinoma Causes...? Effect?


3. Neoplasm: Hepatocellular carcinoma With what dz is this associated?






4. Causes: ACTH or ACTH- like peptide Effect: Cushing's syndrome What neoplasm would create this paraneoplastic effect?






5. Dz: Paget's dz of bone What is the associated neoplasm?






6. Tumor suppressor gene: BRCA1 chromosome? Associated tumor?






7. Chemical carcinogens: Arsenic What is the affected organ?






8. Tumor markers: alpha - fetoprotein






9. Neoplasm: Secondary osteosarcoma and fibrosarcoma With what dz is this associated?


10. Neoplastic progression: normal state - before anything goes wrong


11. Chronic inflammation






12. Granulomatous dz's


13. Characteristics of reversible cell injury






14. Hepatocellular carcinoma What is the assocciated oncogenic virus?






15. Malignant






16. Tumor suppressor gene: p 16 chromosome? Associated tumor?


17. Oncogenic viruses: HBV - HCV What is the associated cancer?






18. Tumor suppressor gene: DCC chromosome? Associated tumor?






19. Causes: Erythropoietin Effect: Polycythemia What neoplasm would create this paraneoplastic effect?






20. Metastasis to bone






21. tumor: N euroblastoma What is the associated oncogene?






22. Tumor nomenclature: Smooth muscle What do you call a benign tumor of this tissue? .. a malignant one?






23. Tumor markers: S-100






24. Adult T- cell leukemia What is the assocciated oncogenic virus?






25. Chemical carcinogens: Nitrosamines (e.g. - in smoked foods) What is the affected organ?






26. Neoplasm: Melanoma - basal cell carcinoma - and esp. squamous cell carcinomas of the skin With what dz is this associated?






27. Oncogenic viruses: EBV What is the associated cancer?


28. Resolution of inflammation






29. Paraneoplastic effects of tumors: Renal cell carcinoma - hemangioblastoma Causes...? Effect?






30. Neoplastic progression: step 2 In situ carcinoma


31. Oncogene: erb - B2 Associated tumor?






32. Paraneoplastic effects of tumors: Leukemias and lymphomas Causes...? Effect?






33. Characteristics of irreversible cell injury






34. Dz: Ulcerative colitis What is the associated neoplasm?






35. Breast and ovarian cancer What is the tumor suppressor gene?






36. Type of amyloid protein: Primary Protein? Derived from...?






37. Paraneoplastic effects of tumors: Small cell lung carcinoma and intracranial neoplasms Causes...? Effect?






38. Tumor suppressor gene: WT1 chromosome? Associated tumor?


39. Tight binding (step 2 of leukocyte extravasation)


40. Dz: Immunodeficiency states What is the associated neoplasm?






41. Necrosis (definition)






42. Neoplasia






43. Melanoma - What is the tumor suppressor gene?






44. Causes: PTH- related peptide - TGF- beat - TNF - IL-1 Effect: Hypercalcemia What neoplasm would create this paraneoplastic effect?






45. Causes: Hyperuricemia due to excess nucleic acid (e.g. - cytotoxic therapy) Effect: Gout - urate nephropathy What neoplasm would create this paraneoplastic effect?






46. tumor: Gastrointestinal stromal tumor (GIST) What is the associated oncogene?






47. Chemical carcinogens: Cigarette smoke What is the affected organ?






48. Hypovolemic/cardiogenic shock






49. Dz: AIDS What is the associated neoplasm?


50. Tumor suppressor gene: NF1 chromosome? Associated tumor?