Test your basic knowledge |

USMLE Step 1 Prep 2

Subjects : health-sciences, usmle-step-1

Instructions:

Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can study here.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.

This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.

1. Scarlet fever - Kawasaki disease - TSS
Hereditary nephritis - sensorineural hearing loss - cataracts
Child uses arms to stand up from squat
Abdominal pain - ascites - hepatomegaly - (also high D dimer - CHF without JVD)
Strawberry tongue

2. Alport's syndrome (type IV collagen)
Smooth - flat - moist white lesions on genitals
Indurated - ulcerated genital lesion
Antineutrophil cytoplasmic antibodies (ANCA)
Hereditary nephritis - sensorineural hearing loss - cataracts

3. Reed - Sternberg cells (Hodgkin's lymphoma)

Warning: Invalid argument supplied for foreach() in /var/www/html/basicversity.com/show_quiz.php on line 183

4. Bell's palsy (LMN CN VII)
Ptosis - miosis - anhidrosis
Triglyceride accumulation in liver cell vacuoles
Achilles tendon xanthoma
Unilateral facial drooping involving forehead

5. Codman's triangle on X- ray (osteosarcoma - Ewing's - pyogenic osteomyelitis)
Dog or cat bite resulting in infection
Strawberry tongue
Pink complexion - dypnea - hyperventilation
Periosteum raised from bone - creating triangular area

6. Horner's syndrome (usually with Pancoast tumor in apex of lung)
Deep - labored breathing / hyperventilation
Polyuria - acidosis - growth failure - electrolyte imbalances
Necrotizing vasculitis (lungs) and necrotizing GN
Ptosis - miosis - anhidrosis

7. MEN 2A (Sipple)
Thyroid (medullary) and parathyroid tumors - pheochromocytoma
Waxy casts with very low urine flow
Iron - containing nodules in alveolar septum
Hilar lymphadenopathy - peripheral granulomatous lesion in middle or lower lung lobes (can calcify)

8. Hemangioma (benign - associated with Sturge - Weber syndrome - in which case it's V1 distribution)
Thrombi made of white/red layers
Vascular birthmark (port - wine stain)
Hair - on - end (crewcut) appearance on X- ray
Extracellular amyloid deposition in gray matter of brain

9. Klebsiella pneumoniae

Warning: Invalid argument supplied for foreach() in /var/www/html/basicversity.com/show_quiz.php on line 183

10. Actinomyces israelii
Branching gram + rods with sulfur granules
Tram - track on LM
Intranuclear eosinophilic droplet - like bodies
Streak ovaries - congenital heart disease - horseshoe kidney

11. Lead poisoning or sideroblastic anemia
Basophilic stipplling of RBCs
Mucosal bleeding and prolonged bleeding time
Fever - chills - headache - myalgia following antibiotic treatment for syphillis
Sudden swollen/painful big toe joint - tophi

12. Aschoff bodies = focal myocardial inflammation with giant cells (rheumatic fever)
Heart nodules (inflammatory)
Chocolate cyst of ovary
Anti - topoisomerase antibodies
liver cysts (parasite)

13. Rapidly progressive crescentic glomerulonephritis

Warning: Invalid argument supplied for foreach() in /var/www/html/basicversity.com/show_quiz.php on line 183

14. Roth's spots (bacterial endocarditis)
Nystagmus - intention tremor - scanning speech - also bilateral internuclear ophthalmoplegia
Retinal hemorrhages with pale centers
Male child - recurrent infections - no mature B cells
Branching gram + rods with sulfur granules

15. Wilson's disease (hepatolenticular degeneration)
Heart nodules (inflammatory)
Low serum ceruloplasmin
Sudden swollen/painful big toe joint - tophi
Disarrayed granulosa cells in eosinophilic fluid

16. Gallstones
Fever - night sweats - weight loss
Athlete with polycythemia
Desquamated epithelium casts in sputum
Fat - female - fertile - forty

17. Cowdry type A bodies (HSV or CMV)
Intranuclear eosinophilic droplet - like bodies
HTN - hypoK - metabolic alkalosis
Sheets of medium - sized lymphoid cells (starry sky)
Vasculitis from exposure to endotoxin casuing glomerular thrombosis

18. Diffuse systemic scleroderma
Sudden swollen/painful big toe joint - tophi
Anti - topoisomerase antibodies
hCG elevated
Dark purple skin / mouth nodules

19. Erb - Duchenne palsy
Hypercoagulability leading to thrombophlebitis
Severe jaundice in neonate
Neonate with arm paralysis following difficult birth. Possible clavicle fx - probably large for gestational age
Current jelly stool

20. Fatty liver disease (alcoholic or metabolic syndrome)
Rash on palms and soles
Swollen gums - mucous bleeding - poor wound healing - spots on skin
Boot - shaped heart on X- ray
Triglyceride accumulation in liver cell vacuoles

21. Becker's muscular dystrophy
Wire loop glomerular appearance on LM
Bounding pulses - diastolic hear murmur - head bobbing
Tennis racket shaped cytoplasmic organelles (EM) in Langerhans cells
Slow progressive muscle weakness in boys

22. Gout/podagra (hyperuricemia)
Sudden swollen/painful big toe joint - tophi
Needle - shaped - negatively birefringent crystals
Yellow CSF
Anti - topoisomerase antibodies

23. Pancoast tumor (can cause Horner's)
Current jelly stool
Bronchogenic apical lung tumor
Stippled vaginal epithelial cells
Hereditary nephritis - sensorineural hearing loss - cataracts

24. Squamous cell carcinoma
Keratin pearls
Gout - MR - self - mutilating behavior in a boy
Lucid interval after TBI
Palpable purpura - joint pain - abdominal pain in a child

25. Glanzmann's thrombasthenia (defect in platelet aggregation due to lack of GpIIb/IIIa)
Mucosal bleeding and prolonged bleeding time
Fat - female - fertile - forty
Dermatitis - dementia - diarrhea
Neonate with arm paralysis following difficult birth. Possible clavicle fx - probably large for gestational age

26. Owl's eye appearance of CMV - Cowdry A bodies
Fat - female - fertile - forty
Brown tumor of bone
Enlarged cells with intranuclear inclusion bodies
Onion - skin periosteal reaction

27. Erythropoietin injection
Degeneration of dorsal column nerves
Severe RLQ pain with rebound tenderness
Dysphagia (esophageal webs) - glossitis (smooth tongue) - iron deficiency anemia
Athlete with polycythemia

28. Orphan Annie nuclei - or 'disbursed chromatin' (papillary carcinoma of the thyroid)
Bloody tap on LP
Adrenal hemorrhage - hypotension - DIC
WBCs that look smudged
Enlarged thyroid cells with ground - glass nuclei

29. MS (Charcot's)
Dog or cat bite resulting in infection
Antidesmoglein (epithelial) antibodies
Boot - shaped heart on X- ray
Nystagmus - intention tremor - scanning speech - also bilateral internuclear ophthalmoplegia

30. Pseudogout
Cold intolerance
WBCs that look smudged
Rhomboid crystals - positively birefringent
Painful blue fingers / toes - hemolytic anemia

31. Paget's
Bone pain - bone enlargement - arthritis - (also increased hat size - fracture - increased alk phos)
Antimitochondrial antibodies
Caf
Rhomboid crystals - positively birefringent

32. Minimal change disease (child - nephrotic)
Waxy casts with very low urine flow
Podocyte fusion on EM
Glomerulus - like structure surrounding vessel in germ cells
Spikes on basement membrane - dome - like endothelial deposits

33. Hypothyroidism
Unilateral facial drooping involving forehead
Cold intolerance
Infant with hypoglycemia - failure to thrive - and hepatomegaly
Rusty sputum

34. Lines of Zahn (arterial thrombus - layers of platelets/RBCs)
Thrombi made of white/red layers
Painful blue fingers / toes - hemolytic anemia
Red 'current jelly' sputum in alcoholic or diabetic patients
Chest pain - pericardial effusion/friction rub - persistent fever following MI

35. Gout - Lesch - Nyhan syndrome - tumor lysis syndrome - loop and thiazide diuretics
Rash on palms and soles
Adrenal hemorrhage - hypotension - DIC
Increased uric acid levels
Mammary gland (blue - domed) cyst

36. Rabies virus - negri bodies (Lyssavirus)
biliary tract disease - cholangiocarcinoma (parasite)
Eosinophilic inclusion bodies in cytoplasm of hippocampal nerve cells
Tennis racket shaped cytoplasmic organelles (EM) in Langerhans cells
Anti - topoisomerase antibodies

37. Chagas disease (Trypanosoma cruzi)
Rash on palms and soles
Bone pain - bone enlargement - arthritis - (also increased hat size - fracture - increased alk phos)
Cardiomegaly with apical atrophy
Antidesmoglein (epithelial) antibodies

38. Henoch - Schonlein purpura (IgA vasculitis)
Single palm crease
Palpable purpura - joint pain - abdominal pain in a child
Short stature - increased incidence of tumors / leukemia - aplastic anemia
biliary tract disease - cholangiocarcinoma (parasite)

39. Job's syndrome
Basophilic nuclear remnants in RBCs
Systolic ejection murmur (crescendo - decrescendo)
Recurrent colds - unusual eczema - high serum IgE
Boot - shaped heart on X- ray

40. Chronic ESRD
Jaundice - RUQ pain - fever
Waxy casts with very low urine flow
Short stature - increased incidence of tumors / leukemia - aplastic anemia
Calf pseudohypertrophy

41. RA (systemic inflammation - joint pannus - boutonniere deformity) - IgM anti IgG
Severe jaundice in neonate
Anti - IgG antibodies
Hyperphagia - hypersexuality - hyperorality - hyperdocility
Dysplastic squamous cervical cells with nuclear enlargement and hyperchromasia

42. Babinski (UMN lesion)
Triglyceride accumulation in liver cell vacuoles
Toe extension / fanning upon plantar scrape
WBC casts in urine
brain cysts - seizures (parasite)

43. Cold agglutinin disease (autoimmune from Mp or mono - from IgM)
Branching gram + rods with sulfur granules
Facial muscle spasm upon tapping
Painful blue fingers / toes - hemolytic anemia
Elastic skin - hypermobility of joints

44. Cancer at head of pancreas obstructing bile duct
Painless jaundice
Swollen gums - mucous bleeding - poor wound healing - spots on skin
Polished - ivory- like appearance of bone at cartilage erosion
Needle - shaped - negatively birefringent crystals

45. Curschmann's spirals (bronchial asthma - can result in whorled mucous plugs)
High level of D dimers
portal hypertension (parasite)
Desquamated epithelium casts in sputum
Urethritis - conjunctivitis - arthritis in a male

46. B symptoms or TB
Palpable purpura - joint pain - abdominal pain in a child
Anti - transglutaminase/antigliadin/anti - endomysial antibodies
Fever - night sweats - weight loss
Swollen - hard - painful finger joints

47. Dressler's (autoimmune post - MI)
hCG elevated
Chest pain - pericardial effusion/friction rub - persistent fever following MI
Honeycomb lung on X- ray
Rectangular - crystal - like - cytoplasmic inclusions in Leydig cells

48. Wegner's (c - ANCA) and Goodpasture's (anti - GBM). Wegner's can also have upper airway involvement
Necrotizing vasculitis (lungs) and necrotizing GN
Desquamated epithelium casts in sputum
Male child - recurrent infections - no mature B cells
Urethritis - conjunctivitis - arthritis in a male

49. MEN 1 (Wermer's)
Renal epithelial casts in urine
Eosinophilic cytoplasmic inclusion in liver cell
Bloody tap on LP
Pancreatic - pituitary - parathyroid tumors

50. Simian crease (Down's)
Enlarged. hard left supraclavicular node
Male child - recurrent infections - no mature B cells
Painless jaundice
Single palm crease