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Test your basic knowledge |
USMLE Step 1 Prep 2
Start Test
Study First
Subjects
:
health-sciences
,
usmle-step-1
Instructions:
Answer 50 questions in 15 minutes.
If you are not ready to take this test, you can
study here
.
Match each statement with the correct term.
Don't refresh. All questions and answers are randomly picked and ordered every time you load a test.
This is a study tool. The 3 wrong answers for each question are randomly chosen from answers to other questions. So, you might find at times the answers obvious, but you will see it re-enforces your understanding as you take the test each time.
1. Acute toxic/viral nephrosis
Renal epithelial casts in urine
Tram - track on LM
Pseudopalisading tumor cells on brain biopsy
Swollen - hard - painful finger joints
2. MS (Charcot's)
Nystagmus - intention tremor - scanning speech - also bilateral internuclear ophthalmoplegia
Boot - shaped heart on X- ray
No lactation postpartum - absent menstruation - cold intolerance
Pink complexion - dypnea - hyperventilation
3. Owl's eye appearance of CMV - Cowdry A bodies
Enlarged cells with intranuclear inclusion bodies
Dog or cat bite resulting in infection
Antinuclear antibodies
Pancreatic - pituitary - parathyroid tumors
4. Interstitial fibrosis
Heterophile antibodies
Anti - transglutaminase/antigliadin/anti - endomysial antibodies
AntiGBM antibodies
Honeycomb lung on X- ray
5. Eburnation (OA resulting in bony sclerosis)
Hyperphagia - hypersexuality - hyperorality - hyperdocility
Glomerulus - like structure surrounding vessel in germ cells
Polished - ivory- like appearance of bone at cartilage erosion
Silver - staining spherical aggregation of tau proteins in neurons
6. Fibrocystic change of the breast
hCG elevated
Mammary gland (blue - domed) cyst
Large lysosomal vesicles in phagocytes - immunodeficiency
Lytic (punched - out) bone lesions on X- ray
7. Parkinson's
Mammary gland (blue - domed) cyst
Stacks of RBCs
Onion - skin periosteal reaction
Resting tremor - rigidity - akinesia - postural instability
8. Babinski (UMN lesion)
Hexagonal - double - pointed - needle - like crystals in bronchial secretions
Erythroderma - lymphadenopathy - hepatosplenomegaly - atypical T cells
Toe extension / fanning upon plantar scrape
Abdominal pain - ascites - hepatomegaly - (also high D dimer - CHF without JVD)
9. RA (systemic inflammation - joint pannus - boutonniere deformity) - IgM anti IgG
Hilar lymphadenopathy - peripheral granulomatous lesion in middle or lower lung lobes (can calcify)
Mucin - filled cell with peripheral nucleus
Anti - IgG antibodies
Erythroderma - lymphadenopathy - hepatosplenomegaly - atypical T cells
10. Auer rods (AML - esp promyelocytic type)
High level of D dimers
Azurophilic granular needles in leukemic blasts
Yellow CSF
Antidesmoglein (epithelial) antibodies
11. Becker's muscular dystrophy
Weight loss - diarrhea - arthritis - fever - adenopathy
Slow progressive muscle weakness in boys
portal hypertension (parasite)
hCG elevated
12. Lead poisoning or sideroblastic anemia
Nutmeg liver
Anti - topoisomerase antibodies
Basophilic stipplling of RBCs
Painful - pale - cold fingers / toes
13. Niemann - Pick disease (genetic sphingomyelinase deficiency)
Smooth - flat - moist white lesions on genitals
Increased a - fetoprotein in amniotic fluid / maternal serum
Infant with failure to thrive - hepatosplenomegaly - neurodegeneration
Cold intolerance
14. Councilman body (toxic or viral hepatitis - often yellow fever)
Lumpy- bumpy appearance of glomeruli on immunofluorescence
Soap bubble in femur or tibia on X- ray
Anti - transglutaminase/antigliadin/anti - endomysial antibodies
Eosinophilic globule in liver
15. OA (osteophytes on PIP (Bouchard) and DIP (Heberden)
Bounding pulses - diastolic hear murmur - head bobbing
Pink complexion - dypnea - hyperventilation
Weight loss - diarrhea - arthritis - fever - adenopathy
Swollen - hard - painful finger joints
16. B symptoms or TB
Renal epithelial casts in urine
Vascular birthmark (port - wine stain)
Infant with hypoglycemia - failure to thrive - and hepatomegaly
Fever - night sweats - weight loss
17. Aortic regurg
Renal epithelial casts in urine
Bounding pulses - diastolic hear murmur - head bobbing
Anticentromere antibodies
Sheets of medium - sized lymphoid cells (starry sky)
18. Pemphigus vulgaris (blistering)
Swollen - hard - painful finger joints
Eosinophilic cytoplasmic inclusion in nerve cell
Antidesmoglein (epithelial) antibodies
Bilateral hilar adenopathy - uveitis
19. Pancoast tumor (can cause Horner's)
Bronchogenic apical lung tumor
Degeneration of dorsal column nerves
Thyroid - like appearance of kidney
Fat - female - fertile - forty
20. Trousseau's sign (adenocarcinoma of pancreas or lung)
HTN - hypoK - metabolic alkalosis
Needle - shaped - negatively birefringent crystals
Arachnodactyly - lens dislocation - aortic dissection - hyperflexible joints
Hypercoagulability leading to thrombophlebitis
21. Conn's (1* hyperaldosterone)
Pink complexion - dypnea - hyperventilation
HTN - hypoK - metabolic alkalosis
Systolic ejection murmur (crescendo - decrescendo)
Heterophile antibodies
22. Fanconi's anemia (esp AML)
Palpable purpura - joint pain - abdominal pain in a child
Sudden swollen/painful big toe joint - tophi
microcytic anemia (parasite)
Short stature - increased incidence of tumors / leukemia - aplastic anemia
23. Koplick spots (measles)
Small - irregular red spots on buccal mucosa with blue - white centers
Hyperphagia - hypersexuality - hyperorality - hyperdocility
Azurophilic granular needles in leukemic blasts
Anticentromere antibodies
24. Choriocarcinoma - hydatidiform mole
Unilateral facial drooping involving forehead
Dilated cardiomyopathy - edema - polyneuropathy
hCG elevated
Short stature - increased incidence of tumors / leukemia - aplastic anemia
25. Rouleax formation (high ESR - multiple myeloma)
Bluish line on gingiva
Triglyceride accumulation in liver cell vacuoles
Ptosis - miosis - anhidrosis
Stacks of RBCs
26. MEN 1 (Wermer's)
Infant with microcephaly - rocker - bottom feet - clenched hands - and structural heart defect
B12 deficiency (parasite)
Pancreatic - pituitary - parathyroid tumors
Dysphagia (esophageal webs) - glossitis (smooth tongue) - iron deficiency anemia
27. Actinomyces israelii
Thyroid - like appearance of kidney
Smooth - flat - moist white lesions on genitals
Branching gram + rods with sulfur granules
Large lysosomal vesicles in phagocytes - immunodeficiency
28. SLE nephropathy
portal hypertension (parasite)
Wire loop glomerular appearance on LM
Anti - topoisomerase antibodies
Toe extension / fanning upon plantar scrape
29. Hemorrhage (hemosiderin) causes brown color of osteolytic cysts. Due to hyperparathyroidism or osteitis fibrosa cystica
Urethritis - conjunctivitis - arthritis in a male
Stippled vaginal epithelial cells
Brown tumor of bone
Dilated cardiomyopathy - edema - polyneuropathy
30. Paragonimus westermani
Situs inversus - chronic sinusitis - bronchiectasis - infertility
Bloody tap on LP
Branching gram + rods with sulfur granules
hemoptysis (parasite)
31. Ferruginous bodies (asbestosis: risk of mesothelioma)
Thrombi made of white/red layers
Iron - containing nodules in alveolar septum
Pseudopalisading tumor cells on brain biopsy
Chorea - dementia - caudate degeneration
32. Parkinson's
Red 'current jelly' sputum in alcoholic or diabetic patients
Dysphagia (esophageal webs) - glossitis (smooth tongue) - iron deficiency anemia
Nodular hyaline deposits in glomeruli
Depigmentation of neurons in substantia nigra
33. Tetralogy of Fallot - RVH
Boot - shaped heart on X- ray
Antimitochondrial antibodies
Ptosis - miosis - anhidrosis
Calf pseudohypertrophy
34. Ancylostoma - Necator (hook worms)
Chorea - dementia - caudate degeneration
Fever - night sweats - weight loss
microcytic anemia (parasite)
Antiplatelet antibodies
35. Kussmaul breathing - DKA
Deep - labored breathing / hyperventilation
Pink complexion - dypnea - hyperventilation
Streak ovaries - congenital heart disease - horseshoe kidney
Glomerulus - like structure surrounding vessel in germ cells
36. Sezary syndrome (cutaneous T cell lymphoma)
Erythroderma - lymphadenopathy - hepatosplenomegaly - atypical T cells
Thyroid - like appearance of kidney
HTN - hypoK - metabolic alkalosis
Colonies of mucoid Pseudomonas in lungs
37. Anencephaly - spina bifida (neural tube defects) - gastrocesis - omphalmocele
Neonate with arm paralysis following difficult birth. Possible clavicle fx - probably large for gestational age
Increased a - fetoprotein in amniotic fluid / maternal serum
Sheets of medium - sized lymphoid cells (starry sky)
Systolic ejection murmur (crescendo - decrescendo)
38. Megaloblastic anemia (B12 - folate deficiency)
Dermatitis - dementia - diarrhea
Hypersegmented neutrophils
Infant with hypoglycemia - failure to thrive - and hepatomegaly
Cutaneous/dermal edema due to CT expansion
39. McBurney's sign
Neonate with arm paralysis following difficult birth. Possible clavicle fx - probably large for gestational age
Renal cell carcinoma - hemangioblastomas - angiomatosis - pheochromocytoma
Severe RLQ pain with rebound tenderness
Vasculitis from exposure to endotoxin casuing glomerular thrombosis
40. Giant cell tumor of bone (generally benign)
Soap bubble in femur or tibia on X- ray
Renal cell carcinoma - hemangioblastomas - angiomatosis - pheochromocytoma
Weight loss - diarrhea - arthritis - fever - adenopathy
Cardiomegaly with apical atrophy
41. Gout
Needle - shaped - negatively birefringent crystals
Red urine in the morning - fragile RBCs
Infant with microcephaly - rocker - bottom feet - clenched hands - and structural heart defect
Restrictive cardiomyopathy (juvenile = cardiomegaly) - exercise intolerance
42. DVT - PE - DIC - Budd - Chiari (D dimer is fibrin breakdown products)
No lactation postpartum - absent menstruation - cold intolerance
Dilated cardiomyopathy - edema - polyneuropathy
HTN - hypoK - metabolic alkalosis
High level of D dimers
43. Reinke crystals (Leydig cell tumor)
Onion - skin periosteal reaction
Waxy casts with very low urine flow
Rectangular - crystal - like - cytoplasmic inclusions in Leydig cells
Hexagonal - double - pointed - needle - like crystals in bronchial secretions
44. Bronchial asthma (Charcot - Leyden crystals: eosinophilic granules)
Hexagonal - double - pointed - needle - like crystals in bronchial secretions
portal hypertension (parasite)
Tennis racket shaped cytoplasmic organelles (EM) in Langerhans cells
Cardiomegaly with apical atrophy
45. Sarcoid
Anti - topoisomerase antibodies
Bilateral hilar adenopathy - uveitis
WBC casts in urine
Pupil accommodates but doesn't react
46. Job's syndrome
RBC casts in urine
liver cysts (parasite)
Heart nodules (inflammatory)
Recurrent colds - unusual eczema - high serum IgE
47. Erythema chronicum migrans from Ixodes tick bite (Lyme)
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48. Gardner's syndrome
Multiple colon polyps - osteomas / soft tissue tumors - impacted / supernumary teeth
Polished - ivory- like appearance of bone at cartilage erosion
Dry eyes - dry mouth - arthritis
Strawberry tongue
49. 2* syphilis - Rocky Mountain spotted fever - coxsackie A
Disarrayed granulosa cells in eosinophilic fluid
Rash on palms and soles
Painful - raised red lesions on palms and soles
Low serum ceruloplasmin
50. Tabes dorsalis - lose proprioception (3* syphilis)
Extracellular amyloid deposition in gray matter of brain
Degeneration of dorsal column nerves
Chorea - dementia - caudate degeneration
Dilated cardiomyopathy - edema - polyneuropathy